Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000624-TA|BGIBMGA000624-PA|IPR001452|Src homology-3,
IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2,
IPR003961|Fibronectin, type III, IPR003962|Fibronectin, type III
subdomain, IPR007110|Immunoglobulin-like, IPR013098|Immunoglobulin
I-set, IPR008957|Fibronectin, type III-like fold
(2130 letters)
Database: celegans
27,539 sequences; 12,573,161 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z73899-13|CAM35841.1| 6629|Caenorhabditis elegans Hypothetical p... 318 2e-86
Z73899-11|CAA98082.2| 7158|Caenorhabditis elegans Hypothetical p... 318 2e-86
Z73899-10|CAA98081.2| 6839|Caenorhabditis elegans Hypothetical p... 318 2e-86
Z73897-6|CAM35838.1| 6629|Caenorhabditis elegans Hypothetical pr... 318 2e-86
Z73897-5|CAA98065.2| 7158|Caenorhabditis elegans Hypothetical pr... 318 2e-86
Z73897-4|CAA98064.2| 6839|Caenorhabditis elegans Hypothetical pr... 318 2e-86
X15423-1|CAA33463.1| 6048|Caenorhabditis elegans twitchin protein. 318 2e-86
AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated... 270 5e-72
AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated... 270 5e-72
AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated... 266 1e-70
AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated... 266 1e-70
AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated... 266 1e-70
U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein. 261 3e-69
Z47070-8|CAA87345.1| 5198|Caenorhabditis elegans Hypothetical pr... 213 1e-54
Z47070-7|CAA87344.1| 5175|Caenorhabditis elegans Hypothetical pr... 213 1e-54
Z47068-9|CAA87336.1| 5198|Caenorhabditis elegans Hypothetical pr... 213 1e-54
Z47068-8|CAA87335.1| 5175|Caenorhabditis elegans Hypothetical pr... 213 1e-54
AF074901-1|AAC26792.1| 5198|Caenorhabditis elegans hemicentin pr... 213 1e-54
AY130758-5|AAN61521.1| 2693|Caenorhabditis elegans 301KDa_2 prot... 140 8e-33
AY130758-4|AAN61520.1| 2708|Caenorhabditis elegans 301KDa_1 prot... 140 8e-33
AY130758-2|AAN61518.1| 18519|Caenorhabditis elegans 2MDa_2 prote... 140 8e-33
AY130758-1|AAN61517.1| 18534|Caenorhabditis elegans 2MDa_1 prote... 140 8e-33
U55364-6|AAA97973.1| 2541|Caenorhabditis elegans Hypothetical pr... 133 2e-30
U80438-4|AAB37634.2| 1415|Caenorhabditis elegans Uncoordinated p... 115 3e-25
U70618-1|AAB17088.1| 1415|Caenorhabditis elegans unc-40 protein. 115 3e-25
AF106579-2|AAM45363.1| 4447|Caenorhabditis elegans Kettin (droso... 113 1e-24
AY819766-1|AAV69856.1| 4250|Caenorhabditis elegans kettin protein. 113 2e-24
AF106579-4|AAK82895.1| 4203|Caenorhabditis elegans Kettin (droso... 113 2e-24
AF106579-1|AAC78200.4| 4889|Caenorhabditis elegans Kettin (droso... 113 2e-24
AB026846-1|BAA90302.2| 4219|Caenorhabditis elegans kettin protein. 113 2e-24
U88183-2|AAM69080.1| 1273|Caenorhabditis elegans Sensory axon gu... 100 2e-20
U88183-1|AAB52657.2| 1269|Caenorhabditis elegans Sensory axon gu... 100 2e-20
AF041053-1|AAC38848.1| 1273|Caenorhabditis elegans SAX-3 protein. 100 2e-20
AY724774-1|AAU21474.1| 750|Caenorhabditis elegans UNC-89-B prot... 98 7e-20
Z49938-4|CAA90189.3| 2180|Caenorhabditis elegans Hypothetical pr... 96 2e-19
Z46811-1|CAA86842.3| 2180|Caenorhabditis elegans Hypothetical pr... 96 2e-19
AF316539-1|AAK01632.1| 2200|Caenorhabditis elegans PTP-3A protein. 96 2e-19
AC024778-2|AAF60566.2| 2325|Caenorhabditis elegans Neuronal igca... 96 2e-19
AY753200-1|AAV31408.1| 402|Caenorhabditis elegans UNC-89 protein. 93 3e-18
AY130758-3|AAN61519.1| 10578|Caenorhabditis elegans 1MDa_1 prote... 90 2e-17
AF106579-3|AAM45364.1| 4369|Caenorhabditis elegans Kettin (droso... 87 1e-16
U58729-3|AAM54204.1| 955|Caenorhabditis elegans Hypothetical pr... 81 1e-14
U58729-2|AAM54203.1| 913|Caenorhabditis elegans Hypothetical pr... 81 1e-14
U58729-1|AAM54202.1| 928|Caenorhabditis elegans Hypothetical pr... 81 1e-14
AF456360-1|AAL60231.1| 928|Caenorhabditis elegans immunoglobuli... 81 1e-14
AF022977-1|ABF71715.1| 1285|Caenorhabditis elegans Peroxidasin (... 79 3e-14
AL110479-24|CAJ76966.1| 1084|Caenorhabditis elegans Hypothetical... 79 5e-14
AL110479-23|CAB60320.2| 1254|Caenorhabditis elegans Hypothetical... 79 5e-14
U39667-7|AAP31442.1| 324|Caenorhabditis elegans Disorganized mu... 74 1e-12
U39667-6|AAC69011.2| 640|Caenorhabditis elegans Disorganized mu... 74 1e-12
AY095447-1|AAM23316.1| 640|Caenorhabditis elegans DIM-1(L) prot... 74 1e-12
AF500489-1|AAM21705.1| 324|Caenorhabditis elegans DIM-1 short p... 74 1e-12
Z54236-7|CAA90982.1| 1471|Caenorhabditis elegans Hypothetical pr... 71 7e-12
U67954-5|AAM54179.1| 444|Caenorhabditis elegans Wrapper/rega-1/... 71 1e-11
AF456363-1|AAL60234.1| 443|Caenorhabditis elegans immunoglobuli... 71 1e-11
U67954-6|AAV28344.1| 452|Caenorhabditis elegans Wrapper/rega-1/... 68 8e-11
AY714779-1|AAU14146.1| 1338|Caenorhabditis elegans UNC-89 protein. 65 6e-10
AF003131-8|AAP68959.1| 1393|Caenorhabditis elegans Uncoordinated... 65 6e-10
AF003131-7|AAV34798.1| 1396|Caenorhabditis elegans Uncoordinated... 65 6e-10
U41530-1|AAA83273.3| 636|Caenorhabditis elegans Hypothetical pr... 64 8e-10
AC006695-2|AAM48553.1| 724|Caenorhabditis elegans Temporarily a... 64 8e-10
AC006695-1|AAU45229.1| 703|Caenorhabditis elegans Temporarily a... 64 8e-10
U00054-3|AAM48546.1| 12268|Caenorhabditis elegans Hypothetical p... 63 2e-09
U00054-2|AAA50715.2| 13100|Caenorhabditis elegans Hypothetical p... 63 2e-09
AY117398-1|AAM78593.1| 13100|Caenorhabditis elegans mesocentin p... 63 2e-09
AF456361-1|AAL60232.1| 1187|Caenorhabditis elegans immunoglobuli... 62 3e-09
AC024817-51|AAP68914.1| 496|Caenorhabditis elegans L1 cam adhes... 62 3e-09
AC024817-49|AAF59572.3| 1187|Caenorhabditis elegans L1 cam adhes... 62 3e-09
Z68006-8|CAA91999.1| 1328|Caenorhabditis elegans Hypothetical pr... 62 4e-09
Z68005-6|CAA91994.1| 1328|Caenorhabditis elegans Hypothetical pr... 62 4e-09
U49830-6|AAK31481.1| 964|Caenorhabditis elegans Neuronal igcam ... 61 7e-09
U49830-5|AAK31482.1| 1227|Caenorhabditis elegans Neuronal igcam ... 61 7e-09
U49830-4|AAU20850.1| 1196|Caenorhabditis elegans Neuronal igcam ... 61 7e-09
U67954-3|AAM54178.1| 436|Caenorhabditis elegans Wrapper/rega-1/... 61 1e-08
AF456362-1|AAL60233.1| 435|Caenorhabditis elegans immunoglobuli... 61 1e-08
U42847-4|AAF23186.1| 1073|Caenorhabditis elegans Immunoglobulin-... 60 1e-08
U50067-4|AAA93439.3| 1144|Caenorhabditis elegans Sensory axon gu... 60 2e-08
U50067-3|AAZ32801.1| 1147|Caenorhabditis elegans Sensory axon gu... 60 2e-08
U50067-2|AAY86218.1| 1328|Caenorhabditis elegans Sensory axon gu... 60 2e-08
U50067-1|AAZ32800.1| 1331|Caenorhabditis elegans Sensory axon gu... 60 2e-08
AB206670-1|BAD97389.1| 1147|Caenorhabditis elegans SAX-7 SHORTFO... 60 2e-08
AB206669-1|BAD97388.1| 1331|Caenorhabditis elegans SAX-7 LONGFOR... 60 2e-08
Z93395-6|CAB07708.1| 3375|Caenorhabditis elegans Hypothetical pr... 57 2e-07
Z93375-8|CAB07569.1| 3375|Caenorhabditis elegans Hypothetical pr... 57 2e-07
U67954-4|AAM54180.1| 345|Caenorhabditis elegans Wrapper/rega-1/... 56 3e-07
AF456364-1|AAL60235.1| 344|Caenorhabditis elegans immunoglobuli... 56 3e-07
Z69664-7|CAA93513.2| 1159|Caenorhabditis elegans Hypothetical pr... 56 4e-07
Z93395-4|CAB07707.1| 2295|Caenorhabditis elegans Hypothetical pr... 55 5e-07
Z93375-7|CAB07568.1| 2295|Caenorhabditis elegans Hypothetical pr... 55 5e-07
U49956-4|AAK77620.1| 1117|Caenorhabditis elegans Variable abnorm... 54 8e-07
U49956-3|AAK77621.1| 1122|Caenorhabditis elegans Variable abnorm... 54 8e-07
AF040269-1|AAC38970.1| 1122|Caenorhabditis elegans Eph receptor ... 54 8e-07
AF475094-1|AAL84635.1| 533|Caenorhabditis elegans SRC-1 protein. 54 1e-06
AF419171-1|AAN31394.1| 533|Caenorhabditis elegans protein tyros... 54 1e-06
AF148954-1|AAD37411.1| 4280|Caenorhabditis elegans myotactin for... 54 1e-06
AF148953-1|AAD37410.1| 4450|Caenorhabditis elegans myotactin for... 54 1e-06
AF040648-5|AAK21413.1| 4450|Caenorhabditis elegans Lethal protei... 54 1e-06
AF040648-4|AAK21414.2| 4280|Caenorhabditis elegans Lethal protei... 54 1e-06
AC084161-5|AAK29735.4| 533|Caenorhabditis elegans Src oncogene ... 54 1e-06
U80436-2|AAC71110.1| 928|Caenorhabditis elegans Uncoordinated p... 52 6e-06
U80436-1|AAC71108.1| 2488|Caenorhabditis elegans Uncoordinated p... 52 6e-06
AF048834-1|AAC12931.1| 2488|Caenorhabditis elegans guanine nucle... 52 6e-06
AF016687-8|AAK72065.1| 737|Caenorhabditis elegans Hypothetical ... 52 6e-06
AF016687-7|AAK72063.1| 881|Caenorhabditis elegans Hypothetical ... 52 6e-06
Z93395-7|CAH04744.1| 2389|Caenorhabditis elegans Hypothetical pr... 51 8e-06
Z93395-3|CAB07706.1| 2482|Caenorhabditis elegans Hypothetical pr... 51 8e-06
Z93375-9|CAH04704.1| 2389|Caenorhabditis elegans Hypothetical pr... 51 8e-06
Z93375-6|CAB07567.1| 2482|Caenorhabditis elegans Hypothetical pr... 51 8e-06
L13458-1|AAA28156.1| 2481|Caenorhabditis elegans basement membra... 51 8e-06
Z83123-13|CAB05615.2| 1208|Caenorhabditis elegans Hypothetical p... 51 1e-05
Z83123-2|CAB05606.1| 1014|Caenorhabditis elegans Hypothetical pr... 51 1e-05
Z81017-11|CAE47468.1| 1051|Caenorhabditis elegans Hypothetical p... 51 1e-05
Z81017-10|CAD44136.1| 1096|Caenorhabditis elegans Hypothetical p... 51 1e-05
Z81017-9|CAC70095.1| 1128|Caenorhabditis elegans Hypothetical pr... 51 1e-05
Z81017-8|CAC70094.2| 988|Caenorhabditis elegans Hypothetical pr... 51 1e-05
Z81017-7|CAB02673.2| 1040|Caenorhabditis elegans Hypothetical pr... 51 1e-05
Z70680-10|CAA94577.2| 1208|Caenorhabditis elegans Hypothetical p... 51 1e-05
U39761-1|AAC46934.1| 1040|Caenorhabditis elegans EGL-15 protein. 51 1e-05
AY288941-1|AAP44084.1| 987|Caenorhabditis elegans EGL-15 protein. 51 1e-05
U49941-8|AAB53876.1| 2427|Caenorhabditis elegans Spectrin protei... 50 2e-05
AL032639-10|CAA21634.1| 108|Caenorhabditis elegans Hypothetical... 50 2e-05
Z81479-9|CAB03937.1| 1117|Caenorhabditis elegans Hypothetical pr... 49 4e-05
AC084152-8|AAK39317.1| 541|Caenorhabditis elegans Hypothetical ... 48 7e-05
AL022270-1|CAB63432.1| 1270|Caenorhabditis elegans Hypothetical ... 48 1e-04
AC024791-20|AAO12400.1| 574|Caenorhabditis elegans Hypothetical... 47 1e-04
AC024791-19|AAF60657.2| 618|Caenorhabditis elegans Hypothetical... 47 1e-04
Z47808-12|CAB61003.1| 902|Caenorhabditis elegans Hypothetical p... 47 2e-04
Z47808-11|CAD36487.1| 928|Caenorhabditis elegans Hypothetical p... 47 2e-04
Z35595-13|CAA84639.2| 902|Caenorhabditis elegans Hypothetical p... 47 2e-04
Z35595-12|CAD36478.1| 928|Caenorhabditis elegans Hypothetical p... 47 2e-04
AJ132947-1|CAC29085.1| 902|Caenorhabditis elegans receptor tyro... 47 2e-04
AJ132946-1|CAC29084.1| 928|Caenorhabditis elegans receptor tyro... 47 2e-04
U49830-7|AAM98046.1| 774|Caenorhabditis elegans Neuronal igcam ... 46 2e-04
Z68005-3|CAA91990.1| 1227|Caenorhabditis elegans Hypothetical pr... 46 3e-04
Z49911-9|CAA90133.1| 682|Caenorhabditis elegans Hypothetical pr... 45 5e-04
Z81045-4|CAB54202.2| 402|Caenorhabditis elegans Hypothetical pr... 45 7e-04
Z81045-3|CAB02817.3| 280|Caenorhabditis elegans Hypothetical pr... 45 7e-04
Z83235-2|CAB05773.2| 265|Caenorhabditis elegans Hypothetical pr... 44 0.001
AL023843-1|CAA19522.2| 260|Caenorhabditis elegans Hypothetical ... 44 0.001
AF456248-1|AAL59606.1| 265|Caenorhabditis elegans secreted 2-im... 44 0.001
Z93395-1|CAB07704.1| 1160|Caenorhabditis elegans Hypothetical pr... 44 0.001
AF456252-1|AAL59610.1| 259|Caenorhabditis elegans secreted 2-im... 44 0.002
Z81543-5|CAB04427.2| 507|Caenorhabditis elegans Hypothetical pr... 43 0.002
Z68005-1|CAA91991.1| 1199|Caenorhabditis elegans Hypothetical pr... 43 0.002
U29487-1|AAA68768.1| 253|Caenorhabditis elegans 2 (zwei) ig-dom... 43 0.003
AL117200-10|CAB55046.1| 151|Caenorhabditis elegans Hypothetical... 43 0.003
AF456251-1|AAL59609.1| 253|Caenorhabditis elegans secreted 2-im... 43 0.003
Z49938-5|CAD31752.1| 1467|Caenorhabditis elegans Hypothetical pr... 42 0.004
Z46811-2|CAD31753.1| 1467|Caenorhabditis elegans Hypothetical pr... 42 0.004
AF316540-1|AAK01633.1| 1487|Caenorhabditis elegans PTP-3B protein. 42 0.004
U40942-9|AAC47074.6| 703|Caenorhabditis elegans Synaptogenesis ... 42 0.006
U80437-19|AAB37630.2| 580|Caenorhabditis elegans Conserved olig... 41 0.008
S47168-2|AAB23866.2| 919|Caenorhabditis elegans UNC-5 protein. 41 0.008
S47168-1|AAB23867.2| 947|Caenorhabditis elegans UNC-5 protein. 41 0.008
AF226866-1|AAF33845.1| 279|Caenorhabditis elegans cell-corpse e... 41 0.008
AF036698-5|AAB88356.2| 567|Caenorhabditis elegans Uncoordinated... 41 0.008
AF036698-4|AAB88355.1| 919|Caenorhabditis elegans Uncoordinated... 41 0.008
AC024776-8|AAK68463.1| 279|Caenorhabditis elegans Cell death ab... 41 0.008
U64858-2|AAN84866.1| 1310|Caenorhabditis elegans Roller: helical... 41 0.011
U64858-1|AAN84864.1| 2456|Caenorhabditis elegans Roller: helical... 41 0.011
U39651-5|AAL11482.2| 395|Caenorhabditis elegans Temporarily ass... 41 0.011
AF188751-1|AAF00548.1| 1083|Caenorhabditis elegans tyrosine kina... 41 0.011
AF078787-11|AAC26948.2| 1083|Caenorhabditis elegans Vegf (vascul... 41 0.011
AC006607-2|AAF60372.1| 137|Caenorhabditis elegans One ig domain... 41 0.011
Z81568-14|CAB04591.2| 608|Caenorhabditis elegans Hypothetical p... 40 0.015
AL032631-14|CAA21577.2| 220|Caenorhabditis elegans Hypothetical... 40 0.015
U23452-9|AAU87820.1| 155|Caenorhabditis elegans Hypothetical pr... 40 0.019
AF039712-1|AAK21402.2| 239|Caenorhabditis elegans 2 (zwei) ig-d... 40 0.019
Z81568-15|CAB04595.2| 610|Caenorhabditis elegans Hypothetical p... 38 0.059
Z81085-3|CAB03115.1| 769|Caenorhabditis elegans Hypothetical pr... 38 0.078
U28409-1|AAC46592.3| 231|Caenorhabditis elegans Hypothetical pr... 38 0.078
AF134186-1|AAD55361.1| 1359|Caenorhabditis elegans XNP-1 protein. 38 0.078
AF000196-11|AAC24256.1| 1359|Caenorhabditis elegans Human xnp ge... 38 0.078
U39651-6|AAL11483.1| 286|Caenorhabditis elegans Temporarily ass... 38 0.10
AF026215-7|AAB71317.1| 415|Caenorhabditis elegans Hypothetical ... 38 0.10
Z72518-2|CAA96700.1| 613|Caenorhabditis elegans Hypothetical pr... 37 0.14
AC087794-1|AAG53701.2| 304|Caenorhabditis elegans Hypothetical ... 37 0.14
AL110485-5|CAB60375.1| 1002|Caenorhabditis elegans Hypothetical ... 37 0.18
Z49131-3|CAA88976.1| 1211|Caenorhabditis elegans Hypothetical pr... 36 0.24
AL110484-6|CAE46683.1| 1345|Caenorhabditis elegans Hypothetical ... 36 0.24
AL110484-5|CAB60334.3| 1343|Caenorhabditis elegans Hypothetical ... 36 0.24
Z81077-4|CAB03071.3| 618|Caenorhabditis elegans Hypothetical pr... 36 0.32
U41110-3|AAA82418.1| 170|Caenorhabditis elegans Helix loop heli... 36 0.32
AF101310-1|AAC69216.2| 765|Caenorhabditis elegans Hypothetical ... 36 0.32
Z69646-2|CAA93475.1| 1087|Caenorhabditis elegans Hypothetical pr... 35 0.55
Z69646-1|CAA93473.3| 1209|Caenorhabditis elegans Hypothetical pr... 35 0.55
U64834-2|AAB04823.2| 1145|Caenorhabditis elegans Hypothetical pr... 35 0.55
Z79756-4|CAB02119.1| 550|Caenorhabditis elegans Hypothetical pr... 35 0.73
Z78066-6|CAB51467.1| 2484|Caenorhabditis elegans Hypothetical pr... 35 0.73
Z78066-4|CAB01522.2| 2607|Caenorhabditis elegans Hypothetical pr... 35 0.73
Z70286-5|CAB61016.1| 3704|Caenorhabditis elegans Hypothetical pr... 35 0.73
U50071-2|AAA93447.2| 6994|Caenorhabditis elegans Uncoordinated p... 35 0.73
U39847-1|AAB41827.1| 6994|Caenorhabditis elegans AO13 ankyrin pr... 35 0.73
D83173-1|BAA11828.1| 1518|Caenorhabditis elegans laminin A protein. 35 0.73
AL110487-14|CAB54429.2| 268|Caenorhabditis elegans Hypothetical... 35 0.73
AF456253-1|AAL59611.1| 268|Caenorhabditis elegans secreted 2-im... 35 0.73
AC024824-1|AAK85503.1| 679|Caenorhabditis elegans Hypothetical ... 35 0.73
AB016806-1|BAA32347.1| 3704|Caenorhabditis elegans laminin alpha... 35 0.73
AB001074-1|BAA19229.1| 3704|Caenorhabditis elegans laminin alpha... 35 0.73
Z81137-2|CAB03465.1| 386|Caenorhabditis elegans Hypothetical pr... 34 0.97
Z70286-6|CAA94293.1| 3672|Caenorhabditis elegans Hypothetical pr... 34 0.97
AL033509-1|CAA22059.1| 1494|Caenorhabditis elegans Hypothetical ... 34 0.97
Z68107-1|CAA92132.1| 264|Caenorhabditis elegans Hypothetical pr... 34 1.3
Z46267-4|CAD45594.1| 517|Caenorhabditis elegans Hypothetical pr... 34 1.3
Z46267-3|CAA86421.3| 522|Caenorhabditis elegans Hypothetical pr... 34 1.3
U41270-3|ABC71846.1| 254|Caenorhabditis elegans Hypothetical pr... 34 1.3
U41034-9|AAA82383.1| 197|Caenorhabditis elegans Hypothetical pr... 34 1.3
U40797-14|AAB37544.2| 200|Caenorhabditis elegans Hypothetical p... 34 1.3
AF067608-1|AAC17654.2| 544|Caenorhabditis elegans Hypothetical ... 34 1.3
AF039047-14|AAM15588.1| 1040|Caenorhabditis elegans Human mlk (m... 34 1.3
AF039047-13|AAM15589.1| 978|Caenorhabditis elegans Human mlk (m... 34 1.3
Z81525-1|CAB04256.1| 897|Caenorhabditis elegans Hypothetical pr... 33 1.7
Z81114-2|CAB03286.1| 604|Caenorhabditis elegans Hypothetical pr... 33 1.7
U41992-7|AAA83358.1| 374|Caenorhabditis elegans Hypothetical pr... 33 1.7
U19615-1|AAB51351.1| 897|Caenorhabditis elegans Nucampholin pro... 33 1.7
Z72503-6|CAA96594.4| 273|Caenorhabditis elegans Hypothetical pr... 33 2.2
X56213-1|CAA39670.1| 1651|Caenorhabditis elegans vitellogenin pr... 33 2.2
U43282-1|AAA83613.2| 547|Caenorhabditis elegans Hypothetical pr... 33 2.2
M11499-1|AAA28165.1| 259|Caenorhabditis elegans protein ( C.ele... 33 2.2
AF047659-3|AAC04423.2| 1650|Caenorhabditis elegans Vitellogenin ... 33 2.2
AF047659-2|AAQ91901.1| 1651|Caenorhabditis elegans Vitellogenin ... 33 2.2
AC006742-1|AAF60499.2| 1393|Caenorhabditis elegans Hypothetical ... 33 2.2
Z81086-3|CAD56586.1| 711|Caenorhabditis elegans Hypothetical pr... 33 3.0
Z81086-2|CAB03121.3| 1045|Caenorhabditis elegans Hypothetical pr... 33 3.0
Z66495-4|CAA91271.1| 954|Caenorhabditis elegans Hypothetical pr... 33 3.0
Z22179-12|CAA80165.1| 144|Caenorhabditis elegans Hypothetical p... 33 3.0
U70850-3|AAB09122.3| 596|Caenorhabditis elegans Zinc finger plu... 33 3.0
U64857-1|AAC25868.1| 2167|Caenorhabditis elegans Hypothetical pr... 33 3.0
U39997-6|AAN60517.1| 942|Caenorhabditis elegans Clear protein 1... 33 3.0
U39997-5|AAN60515.1| 1409|Caenorhabditis elegans Clear protein 1... 33 3.0
U39997-4|AAN60516.1| 1444|Caenorhabditis elegans Clear protein 1... 33 3.0
AY289599-1|AAP43944.1| 596|Caenorhabditis elegans ZAG-1 protein. 33 3.0
AY224511-1|AAP37457.1| 596|Caenorhabditis elegans ZAG-1 protein. 33 3.0
AF047881-1|AAC27552.1| 942|Caenorhabditis elegans truncated CLR... 33 3.0
AF047880-1|AAC27551.1| 1409|Caenorhabditis elegans CLR-1 protein. 33 3.0
AF047661-6|AAC04438.2| 577|Caenorhabditis elegans Hypothetical ... 33 3.0
AC006810-1|AAF59633.1| 182|Caenorhabditis elegans Hypothetical ... 33 3.0
Z68116-7|CAA92170.1| 238|Caenorhabditis elegans Hypothetical pr... 32 3.9
Z29117-5|CAC42271.1| 1704|Caenorhabditis elegans Hypothetical pr... 32 3.9
Z29117-4|CAA82384.2| 1691|Caenorhabditis elegans Hypothetical pr... 32 3.9
AL117204-30|CAB55138.1| 1097|Caenorhabditis elegans Hypothetical... 32 3.9
AF456249-1|AAL59607.1| 238|Caenorhabditis elegans secreted 2-im... 32 3.9
AF357877-1|AAK27715.1| 835|Caenorhabditis elegans receptor-medi... 32 3.9
AF078790-14|AAC26930.1| 335|Caenorhabditis elegans Hypothetical... 32 3.9
AF049142-1|AAC24116.1| 1704|Caenorhabditis elegans ATP-binding c... 32 3.9
AC006835-1|AAF40015.2| 903|Caenorhabditis elegans Hypothetical ... 32 3.9
AC006695-8|AAF39978.1| 786|Caenorhabditis elegans Receptor medi... 32 3.9
AC006695-6|AAF39979.1| 835|Caenorhabditis elegans Receptor medi... 32 3.9
Z95559-8|CAB54437.1| 720|Caenorhabditis elegans Hypothetical pr... 32 5.2
Z81053-1|CAB02877.1| 385|Caenorhabditis elegans Hypothetical pr... 32 5.2
U97407-8|AAN84851.1| 397|Caenorhabditis elegans Prion-like-(q/n... 32 5.2
U97407-7|AAB52480.2| 457|Caenorhabditis elegans Prion-like-(q/n... 32 5.2
U42830-4|AAC48277.1| 487|Caenorhabditis elegans Neuronal igcam ... 32 5.2
U29082-1|AAA68401.1| 251|Caenorhabditis elegans 2 (zwei) ig-dom... 32 5.2
AF456250-1|AAL59608.1| 251|Caenorhabditis elegans secreted 2-im... 32 5.2
AC087079-12|AAK27874.2| 472|Caenorhabditis elegans Hypothetical... 32 5.2
Z81068-8|CAB02988.1| 490|Caenorhabditis elegans Hypothetical pr... 31 6.8
Z81038-15|CAI79153.1| 696|Caenorhabditis elegans Hypothetical p... 31 6.8
Z81038-14|CAB02755.1| 971|Caenorhabditis elegans Hypothetical p... 31 6.8
U80452-6|AAB37858.1| 592|Caenorhabditis elegans Hypothetical pr... 31 6.8
U41556-2|AAM51519.1| 378|Caenorhabditis elegans Cysteine protea... 31 6.8
U41556-1|AAK39189.1| 379|Caenorhabditis elegans Cysteine protea... 31 6.8
U23527-1|AAC46575.2| 1147|Caenorhabditis elegans Neuronal igcam ... 31 6.8
L39939-1|AAA98789.1| 379|Caenorhabditis elegans cathepsin B-lik... 31 6.8
L39894-1|AAA98787.1| 379|Caenorhabditis elegans cathepsin B-lik... 31 6.8
AF047659-10|AAC04430.1| 798|Caenorhabditis elegans Hypothetical... 31 6.8
AC024812-1|AAF59552.2| 364|Caenorhabditis elegans Hypothetical ... 31 6.8
AC006833-6|AAF60950.1| 491|Caenorhabditis elegans Hypothetical ... 31 6.8
Z93385-5|CAB07640.1| 806|Caenorhabditis elegans Hypothetical pr... 31 9.0
Z84712-1|CAB06545.1| 297|Caenorhabditis elegans Hypothetical pr... 31 9.0
Z78419-8|CAB01706.1| 297|Caenorhabditis elegans Hypothetical pr... 31 9.0
Z75952-2|CAB00095.1| 1100|Caenorhabditis elegans Hypothetical pr... 31 9.0
U52515-1|AAA97925.1| 1036|Caenorhabditis elegans hum-1 protein. 31 9.0
U46675-7|AAB52641.1| 1274|Caenorhabditis elegans Hypothetical pr... 31 9.0
U28993-6|AAK31498.2| 639|Caenorhabditis elegans Hypothetical pr... 31 9.0
L13200-3|AAA28192.1| 304|Caenorhabditis elegans C.elegans chrom... 31 9.0
L08403-3|AAT92076.1| 335|Caenorhabditis elegans Hypothetical pr... 31 9.0
AF316599-1|AAG38591.1| 639|Caenorhabditis elegans paracaspase p... 31 9.0
AF040652-4|AAB95021.2| 736|Caenorhabditis elegans Hypothetical ... 31 9.0
AF003137-6|AAB93644.1| 497|Caenorhabditis elegans Hypothetical ... 31 9.0
AC090999-25|AAK26157.2| 921|Caenorhabditis elegans Hypothetical... 31 9.0
>Z73899-13|CAM35841.1| 6629|Caenorhabditis elegans Hypothetical
protein ZK617.1c protein.
Length = 6629
Score = 318 bits (782), Expect = 2e-86
Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)
Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
+K+ + + K +C S +WY ++KEI SG +I+ E
Sbjct: 606 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 665
Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
D G C T L V E + F+ L + E+ A+L ++N+ A +VW
Sbjct: 666 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 725
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
R + I+ ++ EK R L I+ D+ E++ I +D +V V E
Sbjct: 726 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 785
Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
+ +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I
Sbjct: 786 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 845
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
++D GEY C + + A L V+ + F + L + ++ + D L + D
Sbjct: 846 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 903
Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
W++ I KF S TL I K ++ Y + + + V
Sbjct: 904 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 963
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
E P + ++ K G + V +Q P + + N K I + K + I
Sbjct: 964 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 1023
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
A + K + D G + L L N+ G A + + DKP PP P + + +
Sbjct: 1024 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 1083
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N
Sbjct: 1084 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 1143
Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
E +SD E+ Y K + + V+K + EP E+ I G +
Sbjct: 1144 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 1203
Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
+ + W++ G+ T K E++ C DHG+
Sbjct: 1204 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 1256
Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
+ +K + IK + KVG+ I G P PE +W NG L+ +
Sbjct: 1257 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 1315
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
+++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ +
Sbjct: 1316 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 1375
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR
Sbjct: 1376 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 1435
Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
V A N G SE L ++ IK D P D + + I W P K+GG+PI
Sbjct: 1436 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 1494
Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
+Y VE++ + K+WK A I L YQFR+ A N+ G P +K
Sbjct: 1495 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 1554
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
P + + S + T++W GG PI E K KG +
Sbjct: 1555 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 1608
Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
+T+ +EH CI + D +R++ +N+ G + +V L++ PS P P
Sbjct: 1609 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 1663
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L
Sbjct: 1664 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 1721
Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+ TY R+ A N+ G S+ L +D+ K
Sbjct: 1722 KGQTYQFRVKAVNKEGASDALSTDKDTK 1749
Score = 253 bits (619), Expect = 1e-66
Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)
Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
P ++D +E ++K G D +L + P P W ++ K + +
Sbjct: 2739 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 2798
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
+K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP
Sbjct: 2799 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 2858
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD
Sbjct: 2859 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 2918
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
E E + K+ ++ P + + D++ T GG P V
Sbjct: 2919 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2977
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
A ++ A N GE + S + + + + N
Sbjct: 2978 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3037
Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K
Sbjct: 3038 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3097
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG
Sbjct: 3098 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 3157
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L
Sbjct: 3158 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 3214
Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
S+ IV K D P D + V + W P +GG+PI Y VE K + W
Sbjct: 3215 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 3273
Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
A L+ TYQFR+ A N+ G P + P
Sbjct: 3274 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 3333
Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ +K +P+ + T+ + + S H ++
Sbjct: 3334 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 3393
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
D +++I EN G + +V VP P PL+I + +W P
Sbjct: 3394 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 3447
Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
+GG +L Y + D ++ W EVG T K N L Y R+ A N G S+
Sbjct: 3448 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 3505
Query: 2052 PLESDEP 2058
PLE++EP
Sbjct: 3506 PLEAEEP 3512
Score = 251 bits (614), Expect = 5e-66
Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
PKI+ R+ +IK G L VD+ P P W V S + S+
Sbjct: 3621 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 3680
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
+ D+G YKL+++N G + V + D+PS P P + ++ S + W P++
Sbjct: 3681 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 3740
Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+
Sbjct: 3741 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 3800
Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
T E V+ + +P KP + I N+ I++ GG P R D
Sbjct: 3801 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 3856
Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
K + K Y+ +A N G + S + + P
Sbjct: 3857 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 3916
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
+ + + + K G+ ++T P P++ W K G K E TT +T ++
Sbjct: 3917 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 3972
Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
I +RS S I+A N G + + + V DKP PE + +SR + T+ W P
Sbjct: 3973 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 4031
Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+
Sbjct: 4032 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 4090
Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
+ P+VIK D P D V + W P +GGSPI+ Y VE K+
Sbjct: 4091 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 4149
Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
G W + L N TYQFR+ A N G P + +T + P
Sbjct: 4150 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 4209
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
P V + T S L W P +GG+PI YI+E K + WT+ +
Sbjct: 4210 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 4269
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
+N+ EK+E FR+ A N+ G P++ S V +E+ P
Sbjct: 4270 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 4309
Score = 250 bits (612), Expect = 8e-66
Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y
Sbjct: 1870 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 1928
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
L N G + V +L KPS P G + + ++ W PE+ G + I +Y +
Sbjct: 1929 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 1988
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ +
Sbjct: 1989 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 2046
Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
+ P V+KP + + D+ GG P + K + + A ++
Sbjct: 2047 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 2106
Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
++ A N G + S VV + I ED+ KVG
Sbjct: 2107 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 2166
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
I+G P P+V W NG + K I + S + + R S KYTI A+
Sbjct: 2167 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 2225
Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK
Sbjct: 2226 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 2285
Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
+ W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D
Sbjct: 2286 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 2342
Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
P D++ V + W P +GG+PI +Y++E + + +W+ A
Sbjct: 2343 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 2401
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
+ L+ N Y+FR+ A N+ G S P + + P R+ + + + ++
Sbjct: 2402 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 2461
Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
+ P S +P +T + + + ++ K+ + ++ ++ D F I A
Sbjct: 2462 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 2520
Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I
Sbjct: 2521 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 2575
Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
D W+ KV + + L H Y R+ A N G S+PLE+
Sbjct: 2576 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 2627
Score = 243 bits (595), Expect = 1e-63
Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
R+K G + V+ + P P EW +N + +T ++ + LT K D+G
Sbjct: 3045 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 3104
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y
Sbjct: 3105 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 3164
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
VVE QE D W+ + T + L Y+FR AVN S + T + ++
Sbjct: 3165 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 3221
Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
+ P + + + + D+E GG P + +D G ++ A+
Sbjct: 3222 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 3281
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
+ ++ A N G + S G + KP ++ +
Sbjct: 3282 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 3340
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
K G + EG P P W N ++ ++T +S I I R + Y
Sbjct: 3341 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 3400
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E
Sbjct: 3401 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 3460
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K
Sbjct: 3461 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 3518
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
DVP D + + I W P+ NGG+P+ Y VE K++G W
Sbjct: 3519 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 3577
Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
L Y+FR+ A N G S P +D +IT + L P + R + +
Sbjct: 3578 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 3637
Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
++ + + P + + + + +V S + K D ++
Sbjct: 3638 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 3692
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
+ +N +G E +++ PS P PLE+ V + + +W P+ DGGA +
Sbjct: 3693 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 3747
Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP
Sbjct: 3748 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 3805
Score = 242 bits (593), Expect = 2e-63
Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+K G+ + +V P P+ W N K I + K + + + + K +G Y
Sbjct: 2162 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 2220
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+ N G V +N+ + KP+ P P + ++ + W PE+ G I +Y +
Sbjct: 2221 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 2280
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E W+ T ++ +L Y+FR AVN SD ET ++ +
Sbjct: 2281 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 2338
Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
P ++P + T+ + D ++L GG P + + K + + A
Sbjct: 2339 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 2396
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
+ ++ +A N G + S V+ + I + +K K
Sbjct: 2397 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 2456
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + G P P V W+ N+ + N + E S + +K+++R S +T
Sbjct: 2457 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 2516
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE
Sbjct: 2517 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 2576
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K
Sbjct: 2577 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 2636
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
D P D + V + W P +GG+PI +Y VE+K E W
Sbjct: 2637 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 2695
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A + L + Y+FRI A+N+ G P S + + + PP RN +
Sbjct: 2696 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 2754
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
P S +P + E V+ K+ G H ++ D + I
Sbjct: 2755 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 2813
Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
AEN G T V + H PS P PL++ + + +W PE DGGA +
Sbjct: 2814 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 2868
Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E
Sbjct: 2869 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 2923
Score = 235 bits (575), Expect = 3e-61
Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)
Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
+ RIK G+ + L + ++ P P +W N I + S+++ I D
Sbjct: 3337 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 3396
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++
Sbjct: 3397 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 3456
Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
Y+VE + W V + L Y FR AVN S E E
Sbjct: 3457 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 3516
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
+ + P V+KP + DI+ T GG P VT Y KK K + E
Sbjct: 3517 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 3572
Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
++ IA N G + S Q KP I ++ IK
Sbjct: 3573 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 3632
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
K V + G P P W + E + K T+ I KR+ S
Sbjct: 3633 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 3690
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y
Sbjct: 3691 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 3750
Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
+EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K
Sbjct: 3751 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 3809
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
P DN+ + I W P NGGSP+ Y +E K + G+ K
Sbjct: 3810 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 3868
Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
A R+QK TY++R+ A N+ G P S T P +
Sbjct: 3869 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 3925
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
F V +T+ +T SP + I + GK + T S + I +
Sbjct: 3926 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 3976
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
+ D +I A N G + ++++ TV P AP I V + +W
Sbjct: 3977 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 4028
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G
Sbjct: 4029 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 4087
Query: 2049 LSE 2051
LS+
Sbjct: 4088 LSD 4090
Score = 234 bits (572), Expect = 6e-61
Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + +K G+ V V P P +W N ++ + T + ++ L I
Sbjct: 1567 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 1626
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
+D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G
Sbjct: 1627 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 1686
Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T
Sbjct: 1687 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 1745
Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
K+TK ++P ++P K T + + D + + P+ +T Y KK K
Sbjct: 1746 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 1799
Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
+ E ++ ++ A N G E S VV +
Sbjct: 1800 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 1859
Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++
Sbjct: 1860 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 1918
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD
Sbjct: 1919 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 1978
Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
GG + Y IEK + RW+ + T + L EY FRV A N G S+ L
Sbjct: 1979 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 2036
Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
+ I+ K +VP D + V + W + +GG+PI + +E K + +
Sbjct: 2037 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 2094
Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
W+ A + L YQFRI ARN+ GT P D++ P R
Sbjct: 2095 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 2154
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+ + TLK+ +P + K + G+S +I + +
Sbjct: 2155 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 2212
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
K + I+A N G T+S ++ + K + P+ P P+E+ V + W P
Sbjct: 2213 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 2267
Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S
Sbjct: 2268 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 2325
Query: 2051 EPLESD 2056
+PLE++
Sbjct: 2326 DPLETE 2331
Score = 223 bits (545), Expect = 1e-57
Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + IK G ++ V P P W +++ I+ K + L +K++
Sbjct: 2448 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 2507
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G
Sbjct: 2508 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 2567
Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
I YV+E + + W+ + KT + L Y+FR V V+ S+
Sbjct: 2568 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 2624
Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
E + T + +KP K IT + ++L GG P + V +D
Sbjct: 2625 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 2680
Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
+ ++ A N G S V + P
Sbjct: 2681 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 2740
Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
+ N + K K G ++ + + G P P + W G +E+D + ++ + +
Sbjct: 2741 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 2800
Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D
Sbjct: 2801 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 2860
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+
Sbjct: 2861 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 2918
Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
LE+ E I+ K D + D + + W P +GG+PI Y VE++
Sbjct: 2919 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2977
Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
W A + L TYQFR+ A N+ G S P + P
Sbjct: 2978 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3037
Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
R+ V++ TL + +P + + + T I + + ++
Sbjct: 3038 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3097
Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
D ++I A N G + V + +P P PL + + V+ W
Sbjct: 3098 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 3152
Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G
Sbjct: 3153 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 3209
Query: 2050 SEPLESD 2056
S PL SD
Sbjct: 3210 SAPLTSD 3216
Score = 209 bits (510), Expect = 2e-53
Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)
Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
++ ++ G + + + Y P+P + + I + + T ++ +T + +
Sbjct: 4317 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 4376
Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I
Sbjct: 4377 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 4436
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET +
Sbjct: 4437 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 4493
Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
++ + +P +P T+E ++ T GG P Q V R+ + KA
Sbjct: 4494 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 4553
Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
+ N Y + A+N G+ E S + P N + +
Sbjct: 4554 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 4613
Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
+ G+ + P P+V + K NK+ D + + + + I++ + +
Sbjct: 4614 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 4673
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T
Sbjct: 4674 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 4732
Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++
Sbjct: 4733 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 4791
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
+V K +VP+ D+ + W P ++GGS II Y+V+ + +W
Sbjct: 4792 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 4849
Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
AR+ L N ++FRI A+N G S P ++ + PP P +
Sbjct: 4850 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 4909
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
T+ W P +GGS IT Y +E + WT E ++ ++E
Sbjct: 4910 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 4969
Query: 1934 DEIIFRISAENTVGVSLPT 1952
++ FR+ A N G +P+
Sbjct: 4970 NDYEFRVVAINAAGKGIPS 4988
Score = 199 bits (485), Expect = 2e-50
Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
+D + +L + + N ++++ NN G ++ + I D +P PG+P I +
Sbjct: 1414 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 1473
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F
Sbjct: 1474 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 1533
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
R AVN+ SE +E ++ K I + LK+IT + + GG P P
Sbjct: 1534 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 1592
Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
+V W++ ++L+ + T + R Y+ N HG E +
Sbjct: 1593 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 1652
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
+ +P + N ++ D ++ E I Y KL+ + K
Sbjct: 1653 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 1710
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
K + I LK+ + ++ ++A N G S T K YD+P K P ++ +
Sbjct: 1711 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 1769
Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
+ V++EW+PP DGG +T+Y IEK W + V D I L E EY F
Sbjct: 1770 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 1829
Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
RV A N G EA + S +V K P ID E++ + K G
Sbjct: 1830 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 1876
Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
D V + KK W RI+ T + R R G T+ +
Sbjct: 1877 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1936
Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
DK ++ L PS P VS L+W PE +GG+PI +Y IE +
Sbjct: 1937 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 1996
Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
W V G S + + N++ E FR+ A N G S P + + L K+ VP
Sbjct: 1997 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 2053
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
P E+ + V +W P+ DGGAP+ + I +D W E V + +
Sbjct: 2054 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 2110
Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+L E Y RI ARN+ G +P + +
Sbjct: 2111 PNLKEGEEYQFRISARNKAGTGDPSDPSD 2139
Score = 191 bits (465), Expect = 5e-48
Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)
Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
W + ++D +K + S+ K ++R T YT +A + K VEV+
Sbjct: 1892 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 1950
Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
P ++ Y + +D+ V P D + + + + P S++
Sbjct: 1951 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 2007
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
T+ ++ +++R N G +D + N IL K P KP +++ D +
Sbjct: 2008 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 2067
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A
Sbjct: 2068 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 2125
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT
Sbjct: 2126 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 2183
Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
W +GK + +KA EN Y A N +G + + ++ KP
Sbjct: 2184 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 2243
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
K +V D + A ++ PP + + +Y+ D + +
Sbjct: 2244 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 2297
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
+ + L + K+ ++A N+ G S ++ K +D+P +P P +
Sbjct: 2298 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 2356
Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
+ V ++W PPL DGG + +Y IEK RW V T + L N EY FR
Sbjct: 2357 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 2415
Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
V+A N G S+ ++ VI ++ I++ +P +
Sbjct: 2416 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 2475
Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
+ +E G + K ++++ + F I A N G + KI
Sbjct: 2476 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 2532
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
+ T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W
Sbjct: 2533 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 2589
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
V G ++ + E FR++A N G S P E+ L K P AP EI
Sbjct: 2590 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 2648
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ V W P DGGAP+ Y + ++D W +V V + +L E
Sbjct: 2649 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 2708
Query: 2036 TYMIRIYARNEIGLSEPLES 2055
Y RI A+N+ GL +P +S
Sbjct: 2709 KYEFRIRAKNKAGLGDPSDS 2728
Score = 190 bits (463), Expect = 9e-48
Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI
Sbjct: 4057 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 4115
Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N
Sbjct: 4116 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 4175
Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+Y+FR AVN + S +E V K +P V K KN + E + L
Sbjct: 4176 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 4234
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
GG P + + KKL T N ++ IA N GE
Sbjct: 4235 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 4290
Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
E S +V I++ +P+ I+N +DI + G+ + G P +I NGN
Sbjct: 4291 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 4348
Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
EN++ + VI KRS + Y I A+N G + ++ + V D P KP
Sbjct: 4349 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 4407
Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++
Sbjct: 4408 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 4464
Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
L+ N Y FRV A+N G E LE+ + IV K D P E++ + W
Sbjct: 4465 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 4523
Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
+GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N
Sbjct: 4524 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 4583
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
G + IT T P + + + K P + +P +
Sbjct: 4584 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 4643
Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ V + IE + D ++ + EN+ G ++S S+RL+
Sbjct: 4644 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 4695
Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
V P +P IR+ + + W P DGG+P+ Y + D+ + W +V
Sbjct: 4696 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 4754
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
V L + + L +++ Y R+ A + G+SEP E
Sbjct: 4755 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 4788
Score = 183 bits (445), Expect = 1e-45
Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I
Sbjct: 3772 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 3831
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
+I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A
Sbjct: 3832 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 3891
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
VN+ S+++ + ++P + L K + E + +T F PQP +
Sbjct: 3892 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 3949
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
+W ++G K T +++ K A N +GE E + + + KP
Sbjct: 3950 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 4009
Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
+ +H W G E+ YK + + ++ + +
Sbjct: 4010 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 4066
Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
++ L+ ++ I A N G S V V +K +D P P P I + + V++
Sbjct: 4067 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 4125
Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A
Sbjct: 4126 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 4184
Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
N G E SEP+ + ++ P N S +TW ++GG+PI Y
Sbjct: 4185 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 4243
Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
VE K+ G W ++ L Y+FR+ A N G P D + I
Sbjct: 4244 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 4303
Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
+ P N + + T++ P + G PI + + T +V V
Sbjct: 4304 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 4362
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
K D ++ISA N G + V P PT P+ +
Sbjct: 4363 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 4417
Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y
Sbjct: 4418 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 4474
Query: 2040 RIYARNEIGLSEPLESDE 2057
R+ A N+ G+ EPLE+D+
Sbjct: 4475 RVRAENQYGVGEPLETDD 4492
Score = 178 bits (434), Expect = 3e-44
Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D P P KP + + D I+I W+ N G + + Y+VE +E + W T
Sbjct: 3520 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 3579
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S NLK Y FR AVN SD S+ T+ I + + P + + I +
Sbjct: 3580 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 3637
Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
L F G P P TW D + + + YK N
Sbjct: 3638 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 3697
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ GE E V +Q +P + +V D + V+ PP + + N +
Sbjct: 3698 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 3751
Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
++ T S I + +L H ++ + A NT G S S+ V K
Sbjct: 3752 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 3811
Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV
Sbjct: 3812 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 3870
Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
+ ++ + Y +RV+A N G + +S K + P
Sbjct: 3871 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 3930
Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
E + IT P SP D + +EG K + I + +
Sbjct: 3931 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 3984
Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
+I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I
Sbjct: 3985 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 4038
Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S +
Sbjct: 4039 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 4096
Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
V ++ P P+ P EI +N V +W P DGG+P+LGY + W
Sbjct: 4097 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 4155
Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
V V + + L EN TY R+ A N G EP EP P
Sbjct: 4156 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 4203
Score = 176 bits (428), Expect = 2e-43
Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+I+ + ++ +A F E + + RW ++G E+ S+ + K I
Sbjct: 5004 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 5063
Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
+ DAGEY+ EV G+ TA L V+ P + +P IL + Y +
Sbjct: 5064 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 5122
Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
P V ++ + T + D T+ E + EYT ++TT
Sbjct: 5123 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 5182
Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ V P + I T + ++ P + + S +++K +K
Sbjct: 5183 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 5236
Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
+ + + +K + G+ Y+ R+ EN G V + I P PP P
Sbjct: 5237 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 5296
Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
I+++ + + W P + G + Y+VE QE + EW + + NL
Sbjct: 5297 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 5356
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
YR+R +AVN+ +SD +E + + + P + PL ++ E + C
Sbjct: 5357 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 5415
Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
G P+P+ W++ K+L T+K T N+ Y C A N G
Sbjct: 5416 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 5475
Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
T + I+ KP + I + + + G+ + + P E W K+G K+EN+ +
Sbjct: 5476 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 5535
Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I
Sbjct: 5536 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 5594
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y
Sbjct: 5595 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 5651
Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
FR+IA+N G S+ E + P++I
Sbjct: 5652 EFRIIAENKHGQSKPCEPTAPVLI 5675
Score = 171 bits (416), Expect = 5e-42
Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)
Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+++R N GH + VT ++KP P P + +I +S + W+ P G +
Sbjct: 4179 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 4238
Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++
Sbjct: 4239 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 4298
Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
V+ E + P + LK+IT E I++ + GG P+P + + + +
Sbjct: 4299 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 4356
Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
T YK A N +G+ V+ KP I DI
Sbjct: 4357 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 4416
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
Q + W G + I K ++ + +R++ L +
Sbjct: 4417 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 4471
Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
++ + A N G T V +D P P P + E S E++T++W P DG
Sbjct: 4472 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 4530
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
G + Y IEK E + W K A + + + L Y FRV A N G E ++
Sbjct: 4531 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 4590
Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
S PI A P + +P + + +I
Sbjct: 4591 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 4650
Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
+ K I+K + + + N G SD K + P+ P+
Sbjct: 4651 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 4704
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
+ V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + +
Sbjct: 4705 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 4763
Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
+ + + FR+ AE GVS P E V + K+ VP+ P AP +R S W
Sbjct: 4764 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 4822
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N
Sbjct: 4823 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 4880
Query: 2047 IGLSEPLESDE 2057
G S+P E
Sbjct: 4881 AGFSKPSPPSE 4891
Score = 163 bits (396), Expect = 1e-39
Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++
Sbjct: 1118 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 1175
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
+D + W+ PE G + I Y++E +E +W V + + K + Y
Sbjct: 1176 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 1235
Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
+R AVN+ D + + K+ K K +K++ + E I+ G P
Sbjct: 1236 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 1294
Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
P+ W +GK LK ++ + + N G +++ V
Sbjct: 1295 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 1354
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
+ +P DI G + P + ++N +Y K
Sbjct: 1355 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 1414
Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I +
Sbjct: 1415 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 1473
Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
+ + I W+PP DGG + +Y +E +PD W +V V D I L E EY
Sbjct: 1474 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 1531
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
FRV A N G + E + +P+ + W K GG
Sbjct: 1532 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 1589
Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
PI + K +++ + I + ++R+ +N G
Sbjct: 1590 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 1645
Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+
Sbjct: 1646 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 1703
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
W V + H I+ +K+ FR+ A N G S + K+ T
Sbjct: 1704 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 1760
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
++ ++ V W P+ DGGAP+ Y I + W E GKV + I
Sbjct: 1761 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 1820
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
L E Y R+ A N+ G E SD KV+
Sbjct: 1821 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 1850
Score = 142 bits (343), Expect = 3e-33
Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
P PP I + I W P G S I Y VE +E +T W S N+ + +
Sbjct: 4902 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 4961
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
++ L+ + Y FR A+N S + K+ + + V KP T +P N
Sbjct: 4962 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 5019
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
TC G P+P W R+G++L ++++ +E Y
Sbjct: 5020 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 5079
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
N +G + + +Q PVI +D+ GD + G P N +
Sbjct: 5080 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 5136
Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
++ D I + +I I L + +Y SN +G ++ L V P P+G
Sbjct: 5137 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 5196
Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L
Sbjct: 5197 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 5255
Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
EN EY FRV AQN G L SE PI+ + D P + + V ++W
Sbjct: 5256 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 5314
Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
+GG + Y VE ++E +W + L Y++R++A N+ G
Sbjct: 5315 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 5374
Query: 1848 S 1848
S
Sbjct: 5375 S 5375
Score = 132 bits (320), Expect = 2e-30
Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)
Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
K T KL V V++ P K R I+ + + + ++ P+ N + + +++K
Sbjct: 4391 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 4446
Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
+ T +V N DA +++R EN G + +E + I+ D P P
Sbjct: 4447 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 4506
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ +
Sbjct: 4507 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 4566
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
L +Y FR A N + S + + + P + + ++I E +
Sbjct: 4567 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 4624
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
+ F P PKVT+ + K+ K Y + Y N
Sbjct: 4625 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 4684
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
G S + + KP S + I+ + D W+ + G P I K
Sbjct: 4685 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 4741
Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
+ + K +++ + + L + + ++ + A G S V V ++
Sbjct: 4742 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 4801
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D +
Sbjct: 4802 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 4858
Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
+ + L +N E+ FR+IA+N GFS+ + SE +K+ P I
Sbjct: 4859 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 4917
Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
ITW ++GGS I Y VEI++ G W + KL Y+FR+
Sbjct: 4918 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 4977
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A N G +P I I + + S+P+ V E T++
Sbjct: 4978 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 5015
Score = 129 bits (311), Expect = 2e-29
Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ +
Sbjct: 4787 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 4845
Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
WI+ K Q + L+ N + FR A N S S +E ++ P
Sbjct: 4846 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 4905
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
+ K+I + + G K+T Y R+ G L T + Y R
Sbjct: 4906 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 4963
Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
++ +A N G+ S G IQ+ +P I + ED Q + +
Sbjct: 4964 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 5023
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
AV G P P W +NG +L Y + IKE+ + +YT+E SN
Sbjct: 5024 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 5081
Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
G+ + L V P PVI +++ TI L G L K P
Sbjct: 5082 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 5127
Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
+ + ++D D T I + +++ ++ G E S T L+V
Sbjct: 5128 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 5187
Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
P I + ++W P +GGS I Y VE + K +W
Sbjct: 5188 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 5247
Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
I L N Y+FR+ A+NE G P S+ I PP+ P N + +
Sbjct: 5248 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 5307
Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
VTL W P S+GG + YI+E + + W + + + + N+ + + +R+
Sbjct: 5308 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 5367
Query: 1942 AENTVGVS 1949
A N G+S
Sbjct: 5368 AVNDAGLS 5375
Score = 124 bits (299), Expect = 7e-28
Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)
Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
W P +GGSPI +Y K++++ KW K + L + Y+FR+ A
Sbjct: 4720 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 4779
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
+ G S P D + P+QP V + S L+W +P +GGS I Y ++
Sbjct: 4780 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 4838
Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
++ W + + E C + +++ E FRI A+N G S P+ S+ +L
Sbjct: 4839 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 4895
Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
+ P PP + + +G N +W P DGG+ + GYN+ IR+ T+W
Sbjct: 4896 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 4954
Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
+V +F + L E + Y R+ A N G P P K+ GS
Sbjct: 4955 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5002
Score = 99 bits (238), Expect = 2e-20
Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)
Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P I WY++ + I + +N+ +I N D+G Y C A+ G +H
Sbjct: 626 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 682
Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
++ K +F+ L + E K +L C+ + WY K I D R II+
Sbjct: 683 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 742
Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
+ GR I +D + + V+E F+ ++ +V E D+A
Sbjct: 743 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 802
Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+
Sbjct: 803 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 862
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
A++ +V+ + I L++ +V + + T + WF++G +I
Sbjct: 863 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 921
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+ LKI ++++A Y + + + +TV E
Sbjct: 922 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 962
Score = 99.1 bits (236), Expect = 3e-20
Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)
Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ +
Sbjct: 1066 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 1123
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
++++KE E FR+ A N G+S P +SV + VP P ++ V +
Sbjct: 1124 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 1182
Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
+W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A
Sbjct: 1183 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 1242
Query: 2045 NEIGLSEPLESDEPFKV 2061
N+ G +P + +P K+
Sbjct: 1243 NKAGPGDPCDHGKPIKM 1259
Score = 98.3 bits (234), Expect = 5e-20
Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
+S + TL W P ++GGS IT+Y++E + + W VTV +V + + + +
Sbjct: 5200 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 5256
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW
Sbjct: 5257 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 5313
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P DGG L GY + ++ W + +N+ +L + Y R++A N+ G
Sbjct: 5314 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 5373
Query: 2049 LSEPLESDEPFKVIPGEG 2066
LS+ E D+ G G
Sbjct: 5374 LSDLAELDQTLFQASGSG 5391
Score = 94.3 bits (224), Expect = 9e-19
Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)
Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
L D+ +T+ K + L +H ++ + A N G S + ++ +D P
Sbjct: 5233 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 5292
Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
+ P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y
Sbjct: 5293 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 5351
Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
+ L + +Y +RV A N G S+ E + + + A ++ E
Sbjct: 5352 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 5410
Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
F E + GSP +Y+ + + K+ I L+ + ++ A
Sbjct: 5411 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 5469
Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
N GT + T + PP + + T++ P +
Sbjct: 5470 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 5525
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + ++ S I T I N +D +R+ EN+VG T + +V
Sbjct: 5526 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 5579
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K
Sbjct: 5580 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 5638
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
I L Y RI A N+ G S+P E P +IPG+
Sbjct: 5639 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 5678
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
T LDVP I E + W P NGG+ ++ Y VE + W+
Sbjct: 3417 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 3476
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A++ KL Y FR+ A N G S P +++ I P V++
Sbjct: 3477 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 3536
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
+ +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+
Sbjct: 3537 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 3594
Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
A N G S P++ ++ K + P TA +I++ N+ + G P+
Sbjct: 3595 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 3649
Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
P + + + V K ++ F +++ Y +++ +NE+G E
Sbjct: 3650 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 3702
Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
+ F+VI + A E P E ++V
Sbjct: 3703 EAIFEVIVQDRPSAPEGPLEVSDV 3726
Score = 88.6 bits (210), Expect = 4e-17
Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ +
Sbjct: 6053 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 6111
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
+TI + K D+G YT++A+NS G E + V +E PL E K
Sbjct: 6112 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 6164
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
++ R P T++ N +I + +T + G + D D
Sbjct: 6165 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 6224
Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
V+ S S +D + T+ + + V+ TV TK
Sbjct: 6225 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 6276
Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
+S R + + G +I+ + D + + L K T +P F
Sbjct: 6277 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 6336
Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
+L D E + A ++ + ++ W +GE I +++ L I +
Sbjct: 6337 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 6396
Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
DEG+Y C + E A +TV VE + L + VN
Sbjct: 6397 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 6456
Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV
Sbjct: 6457 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 6516
Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
+ +++ V E + RLP + P T+E + E L V W++
Sbjct: 6517 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 6576
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
IE E+ + L I+ +DD Y ++ K
Sbjct: 6577 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 6616
Score = 87.8 bits (208), Expect = 7e-17
Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S
Sbjct: 5417 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 5476
Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
L++ KP P +++ TIE K P ++ + + +NN
Sbjct: 5477 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5536
Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
+ D+ T I + +RV+ +N VG V T DVP
Sbjct: 5537 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 5590
Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
+D E+V ++W P +GGS + +Y +E ++ G W I+ L
Sbjct: 5591 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 5649
Query: 1834 TYQFRIYARNEIGTSLP 1850
Y+FRI A N+ G S P
Sbjct: 5650 QYEFRIIAENKHGQSKP 5666
Score = 70.5 bits (165), Expect = 1e-11
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
+P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V +
Sbjct: 5190 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 5248
Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
+ + L ENH Y R+ A+NE G+ PL S+ P
Sbjct: 5249 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 5282
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP
Sbjct: 5364 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5423
Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
W CK + GD + I+ D YT +A NS G T A +
Sbjct: 5424 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 5482
Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
++ +P +FI ++ +KG TI+L P W ++ E I +
Sbjct: 5483 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5536
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ D + L I+N E D G+Y+ V NS G S VT+
Sbjct: 5537 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 5579
Score = 66.9 bits (156), Expect = 1e-10
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ K +G + F C+V P +TW + +K S + Y+ ++ L
Sbjct: 6056 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 6114
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I V +D G +T AKN+ G T E IV ++ H + +
Sbjct: 6115 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 6170
Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
E P F+ + + + + L C L P P I W+ G V ++ + V+
Sbjct: 6171 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 6229
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
S + CS L+I N + GTYTV A N G VL ++T EP P+V
Sbjct: 6230 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 6278
Score = 66.5 bits (155), Expect = 2e-10
Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P+F+ + + G + PEP I WL GE I ++ + +
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 6390
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
L+I++ KK EG Y A N G+ L +K + + +V + L
Sbjct: 6391 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 6450
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
IV GESV A+V G P + W +N + + DG+T S TI D
Sbjct: 6451 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 6508
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
G Y L+ S+G S V E A+PP + R ++ G+
Sbjct: 6509 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 6563
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
++ W+R +E I +E + G +L I NV+ + D G Y
Sbjct: 6564 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 6608
Score = 62.9 bits (146), Expect = 2e-09
Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
E P L G S SA V G P P I W N + + ++ T
Sbjct: 6332 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 6391
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
+ + K DEG Y +A NS G +T A +TV ++P + E L + +
Sbjct: 6392 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 6451
Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
+ G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+
Sbjct: 6452 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 6509
Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
G Y+ V S S + V + + V L S G + +E + ++
Sbjct: 6510 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 6569
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
+W+ ++I + + ++ G D G+ + +VK+++
Sbjct: 6570 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 6617
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
P F +L T G + +F V G P P I W I S F+ Y ATL
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 6392
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
I + D G + C A N+AG + L V + PL + + V
Sbjct: 6393 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 6443
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
+K + V+ G + E R+ PE ++ W+ G+E+ + S++ +
Sbjct: 6444 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 6494
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ + I + G Y + V +G + + + GEK P V S+
Sbjct: 6495 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 6549
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
G S + + T+ W + ++ + + + + G+T + I K + D+G+Y
Sbjct: 6550 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 6608
Query: 804 TLK-AENSEGIAETSAVI 820
K + + IA+ +A +
Sbjct: 6609 VAKVVKEKKAIAKYAAAL 6626
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
VE E D W R + P N Y+ RK R +V+D G D++
Sbjct: 5328 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 5385
Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
E P+I++ L + G TFE E++ RWFK E+ ++ L
Sbjct: 5386 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 5444
Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
G KQ L I D DDA EY+C NS T N ++ + +P
Sbjct: 5445 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 5499
Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
A + ++IP + + W K IE+ KF++ +D K TL I + +D E
Sbjct: 5500 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 5559
Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
Y V+ ++ T + V V PP+
Sbjct: 5560 YRVVVENSVGSDSGTVNVTVADVPEPPR 5587
Score = 54.8 bits (126), Expect = 6e-07
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V
Sbjct: 2410 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 2467
Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E
Sbjct: 2468 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 2527
Query: 816 TSAVITV-EEPTEEN 829
+ I V ++PT N
Sbjct: 2528 ATVKINVIDKPTSPN 2542
Score = 53.6 bits (123), Expect = 1e-06
Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y + A N G+++ + + + E P ++ ++ + + ++ +P P
Sbjct: 5364 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5423
Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A +
Sbjct: 5424 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 5481
Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
I + F+ YE ++G+T+ L+ + +W + ++I I +
Sbjct: 5482 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 5541
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
+ D G + +V++ ++ T+ V +PE
Sbjct: 5542 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 5584
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
C L V + +E Y V AVN+ G P +K+K + P +K + ++
Sbjct: 1221 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 1279
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
GE++ + G P P W N KP+KA+ I+K + D G +T+
Sbjct: 1280 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1339
Query: 806 KAENSEGIAETSAVITV 822
+NS G +++A +TV
Sbjct: 1340 TLKNSSGSCDSTATVTV 1356
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P V L + G V FEC++ G PRP+ WF+ + + + + D L+
Sbjct: 5394 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 5452
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
I ++ +DA +TC A N++G S+ L ++
Sbjct: 5453 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 5484
Score = 51.6 bits (118), Expect = 6e-06
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
+ S P+V +G P+++E +++ V + E+ IL+ +V G+P PT W K ++ V +
Sbjct: 436 KTSTPLVPSGASGSA--PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVIS 493
Query: 778 ---LPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEG 812
+DG H++ + K + +DEG YTL EN G
Sbjct: 494 GGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHG 532
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
+I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V
Sbjct: 1817 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 1876
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
V G P P W N KPV + + + + +L+ K G+YTL A N+
Sbjct: 1877 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1936
Query: 812 GIAETSA-VITVEEPT 826
G + S VI + +P+
Sbjct: 1937 GSDKHSVEVIVLGKPS 1952
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
I LP E P V K P F C+ G P P W R +
Sbjct: 4986 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 5045
Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
S ++ + D V I+EV+ DAG +T N G ++T L+V+AP
Sbjct: 5046 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 5096
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V
Sbjct: 1522 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 1581
Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P P + W K N+ ++ L + + H+I + D G Y L +NS
Sbjct: 1582 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 1641
Query: 811 EGIAETSAVITV-EEPTEEN 829
G E A +TV + P++ N
Sbjct: 1642 HGADEEKANLTVLDRPSKPN 1661
Score = 49.6 bits (113), Expect = 2e-05
Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
+TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y
Sbjct: 6326 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 6385
Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
+ Y C A N G+ +T + ++ +P++ + +E
Sbjct: 6386 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 6445
Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
KH G+ A ++G P EV+W +NG +L N + +I+ +T I
Sbjct: 6446 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 6504
Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
S + Y +E + GT+ V V +L V + + P
Sbjct: 6505 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 6538
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
P +L + + G A F ++ + + L+ W +G I S+ + + K L+
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6393
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
I D D G+Y C NS + A LTV ++P +N LR+ + + +
Sbjct: 6394 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 6453
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
V + +V W + + + +K ++ D + + I D Y
Sbjct: 6454 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 6513
Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
+ + S L V + P + G ++++ +W
Sbjct: 6514 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 6573
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
S+ I+K + K + L IK VE D GIY
Sbjct: 6574 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 6608
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
+ SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++
Sbjct: 4950 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 5009
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
+ + + + VG P PT W +N + + SDG + TI +
Sbjct: 5010 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 5068
Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825
+ D G YT++ N G +A + V+ P
Sbjct: 5069 I-DAGEYTVEVSNPYGSDTATANLVVQAP 5096
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/121 (26%), Positives = 48/121 (39%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +KA N G + S + P + + F VK T+ V P P
Sbjct: 3005 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 3064
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
I W+ N +S + + +N + T + DSG YK VA+N +GK H V
Sbjct: 3065 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 3124
Query: 923 I 923
I
Sbjct: 3125 I 3125
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
T V+K Y VVAVN+ G T + E P+ L K V+ GE ++
Sbjct: 3877 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 3936
Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G
Sbjct: 3937 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 3993
Query: 813 IAETSAVITV 822
AE + ITV
Sbjct: 3994 EAEANIKITV 4003
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+
Sbjct: 1507 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 1552
Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
P FI + + ITVK T++ ++ P+P + W++ N+ + +T
Sbjct: 1553 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 1610
Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
D E I + S + D G+Y+ NS G A +T+
Sbjct: 1611 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 1653
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
G + EC + P P+ W FKG +E+V ++ + D VL I ++
Sbjct: 5408 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 5462
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
YT A N G S L+IKT P+V P K ++GE++ L P+
Sbjct: 5463 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 5518
Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
W K+ + ++ +D ++ I + +D G Y + ENS G + +
Sbjct: 5519 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 5577
Query: 821 TVEEPTEENAEPPLF 835
TV + EPP F
Sbjct: 5578 TVADV----PEPPRF 5588
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
+ N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L
Sbjct: 2701 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 2760
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
+ V G P PTITW PV++ + T K+ D G Y +KAEN G
Sbjct: 2761 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 2820
Query: 813 IAETSAVITV 822
+TV
Sbjct: 2821 TDTAEVKVTV 2830
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
K+E + + A NS G E S + E+ P IN ++ITV+ TI++ +
Sbjct: 4275 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 4334
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
NP P I + N I +E D E+VIT S+ D+G YK A+N GK
Sbjct: 4335 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 4392
Query: 916 S 916
+
Sbjct: 4393 T 4393
Score = 45.2 bits (102), Expect = 5e-04
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)
Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S
Sbjct: 2178 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 2232
Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
+ I +K+K+ +P IE R G P K N K +P
Sbjct: 2233 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 2292
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
GDTH T+ K D + +KA NSEG + ET I + P + P
Sbjct: 2293 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 2346
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
+ N+K+ +E + + A N+ G + S P + P++ E L V+ G ++
Sbjct: 2110 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 2169
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
+ G P P +TW N K + + + + + PK + K G YT+ A N G
Sbjct: 2170 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 2229
Query: 813 IAETSAVITVE-EPTE 827
+ I V+ +PT+
Sbjct: 2230 TDSVTINIKVKSKPTK 2245
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
N+K E + V+AVN G + S P +I P+++ + + ++ G + L
Sbjct: 3583 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 3642
Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
+G P PT TW + P D + + +I P K D G Y LK +N G
Sbjct: 3643 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 3702
Query: 815 ETSAVITVEE 824
E + V++
Sbjct: 3703 EAIFEVIVQD 3712
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G
Sbjct: 4265 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 4324
Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
E++ I GNP+P I N P+ + T D + I I K D G Y +
Sbjct: 4325 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 4384
Query: 807 AENSEG 812
A N G
Sbjct: 4385 ATNKYG 4390
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P
Sbjct: 3004 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 3063
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
P+I WF + + + + + DN L + D+G + VA N +G
Sbjct: 3064 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 3115
Score = 41.9 bits (94), Expect = 0.005
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ ++A+N G+ + S + N P + N QEI VK L V+ P P
Sbjct: 2712 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 2770
Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ITW + + S N DG+ V + S D+G Y A N G + +V
Sbjct: 2771 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 2828
Query: 922 TI 923
T+
Sbjct: 2829 TV 2830
Score = 41.5 bits (93), Expect = 0.006
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
KN + +AL D T ++ LK +E + + A N G + S N
Sbjct: 2091 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 2147
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
P + + TVK T+K + + P P +TW N + I S+ +N I
Sbjct: 2148 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 2205
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
SG Y A+N G S VTI+++
Sbjct: 2206 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 2238
Score = 41.1 bits (92), Expect = 0.008
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT
Sbjct: 2458 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 2516
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A NA G +T ++ +++ P S +G
Sbjct: 2517 IKAVNANGEDEATVKINVIDKPTSPNG 2543
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++ + + YP+ + W + I+ + F + DD ATL I ED G +
Sbjct: 5504 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 5562
Query: 584 VAKNAAGFASSTTELIV 600
V +N+ G S T + V
Sbjct: 5563 VVENSVGSDSGTVNVTV 5579
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP F LR + + C ++G P P I W + + +D
Sbjct: 6173 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 6230
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V +L I +DAGT+T A N G S L V+
Sbjct: 6231 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 6268
Score = 39.9 bits (89), Expect = 0.019
Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P KP+ + C V PEP WL G E+ E+ E+ +
Sbjct: 5001 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 5058
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
Y +K V G YTV N G + L ++ PP + + + + I+ G+
Sbjct: 5059 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 5112
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
V L G + N + + PT + D H + + V++ G Y
Sbjct: 5113 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 5172
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G A T + V E + PL I+ T T+ VT ++
Sbjct: 5173 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 5227
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+S E +T + +++ ++T + E +++ A N G
Sbjct: 5228 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 5272
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
++ E+ + I E ++ V P+ + P + + +TV E T L +V+ +P P+
Sbjct: 425 MRRESVQEILEKTSTPLV--PSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTF 482
Query: 865 TWYRNNEIISPSETITQNFDGE--NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
W++ + + DG+ + L + S+ D G Y N G S ++
Sbjct: 483 RWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQ-DEGPYTLTIENVHGTDSADVKLL 541
Query: 923 IDVEKVTFVKHLQKSYETEEG 943
+ + + + K E++ G
Sbjct: 542 VTSDNGLDFRAMLKHRESQAG 562
Score = 39.1 bits (87), Expect = 0.034
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T
Sbjct: 1873 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 1929
Query: 583 CVAKNAAGFASSTTELIV 600
A NA+G + E+IV
Sbjct: 1930 LTATNASGSDKHSVEVIV 1947
Score = 39.1 bits (87), Expect = 0.034
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N
Sbjct: 6198 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 6256
Query: 1652 GTSSVEVTLKVYDKPSKP 1669
G E L V K +P
Sbjct: 6257 GVDVSECVLTVQTKGGEP 6274
Score = 38.7 bits (86), Expect = 0.045
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
++ + E ++K P+ S AP VE + T C+V G P P WF
Sbjct: 427 RESVQEILEKTSTPLVPSGASGS-APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWF 485
Query: 545 RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + + F+ D ++ L + + +D G +T +N G S+ +L+V
Sbjct: 486 KGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV--- 542
Query: 604 LSDHG 608
SD+G
Sbjct: 543 TSDNG 547
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 4/126 (3%)
Query: 1255 IRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
IR+ + D + E +L+ ST + PKIV+ + L
Sbjct: 418 IRRSSIDMRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGS 477
Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCG--HAD 1370
P P W S+ + K D K + +L + K + D G Y L +EN G AD
Sbjct: 478 PAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSAD 537
Query: 1371 VEMNVT 1376
V++ VT
Sbjct: 538 VKLLVT 543
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
+ +K Q + V A+N+ GE+ S P + P++ + + V+ G+++
Sbjct: 2994 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 3053
Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
V G P P I W N P+ + T D +T + T L K D G Y + A N
Sbjct: 3054 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 3113
Query: 811 EGIAETSAVITV 822
G E + +
Sbjct: 3114 SGKDEHEVDVNI 3125
Score = 37.5 bits (83), Expect = 0.10
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
KS+ D H + KP K V+D E +Y +KA N G + + + A
Sbjct: 1206 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 1265
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P +++ +K TIK ++ P+P W N + + + + + +
Sbjct: 1266 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 1325
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I N DSG + NS+G A VT+
Sbjct: 1326 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 1356
Score = 37.1 bits (82), Expect = 0.14
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT--KEKTSVIRIKELKRSHSSKYTIEAS 1648
++T + G P P W+K ++ + + T KE T + + + + YT+
Sbjct: 469 ILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIE 528
Query: 1649 NTAGTSSVEVTLKV 1662
N GT S +V L V
Sbjct: 529 NVHGTDSADVKLLV 542
Score = 37.1 bits (82), Expect = 0.14
Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y
Sbjct: 6454 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 6512
Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+L + + V V + +K PP + + SS P G ST + +
Sbjct: 6513 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 6559
Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
E++ ++ T +W + ++++KT ++++ V + D + KV+K
Sbjct: 6560 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 6614
Query: 1476 ETK 1478
E K
Sbjct: 6615 EKK 6617
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+E + + A N G ++ S N +P + + + +T+K +I V+
Sbjct: 2410 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 2469
Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+
Sbjct: 2470 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 2527
Query: 917 HGARVTIDVEKVT 929
++ + ++K T
Sbjct: 2528 ATVKINV-IDKPT 2539
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
L+N + N +LTC G P P + W +DG + + R
Sbjct: 6185 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 6244
Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
Y A ND G + CV+ +Q K
Sbjct: 6245 AGTYTVTATNDLGVDVSECVLTVQTK 6270
Score = 36.3 bits (80), Expect = 0.24
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++
Sbjct: 1550 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 1609
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
+ + L I D G + KN+ G L +++ P +G
Sbjct: 1610 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 1662
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PP V W+K+ +L+ +Y + I +K +YT+ A N+ GT V L
Sbjct: 6084 PPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 6143
Query: 1661 KV--YDKPSKPE 1670
V + +P K E
Sbjct: 6144 NVTRHSEPLKFE 6155
Score = 35.5 bits (78), Expect = 0.42
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVK 845
H +T L PKK + V A + S IT + PT + ++I
Sbjct: 4562 HRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLT---RDILAY 4618
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDY 904
K++ +P P +T+ + ISP++ + + + +T SE+ D G Y
Sbjct: 4619 AGERAKILVPFAASPAPKVTFSKGENKISPTDPRVK-VEYSDFLATLTIEKSELTDGGLY 4677
Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
NS G S R+ + V+K +H++
Sbjct: 4678 FVELENSQGSDSASIRLKV-VDKPASPQHIR 4707
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++++ + G P P+ W +K +M + + I D+G FT
Sbjct: 1281 GETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMS-SERGKHIMKIENAVRADSGKFTI 1339
Query: 584 VAKNAAGFASST-TELIVEAPLSDHG 608
KN++G ST T +V P G
Sbjct: 1340 TLKNSSGSCDSTATVTVVGRPTPPKG 1365
Score = 34.7 bits (76), Expect = 0.73
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 499 EKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDF 556
++ ++ +++AP I E L G+T++F ++G P P +TW F I +
Sbjct: 2139 DRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQI 2198
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
+ ++ ++ + + + +G +T A N G S T + V++
Sbjct: 2199 E---NEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKS 2241
Score = 33.5 bits (73), Expect = 1.7
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G V G P P ITW F T + S D ++D ++ D GT+
Sbjct: 2755 GQDFSLNIPVSGEPTPTITWTFEGTPV--ESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 2812
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A+N G ++ ++ +++ P S G
Sbjct: 2813 IKAENENGTDTAEVKVTVLDHPSSPRG 2839
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/97 (21%), Positives = 34/97 (35%), Gaps = 2/97 (2%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P + P+ V E +L C++ P P W E++ + H
Sbjct: 448 GSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHT 507
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
L + + EG YT+ N G S + L +
Sbjct: 508 V--ALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 542
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+PP + + V G D L + P P I W F+G + D+ + + E
Sbjct: 2738 VPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTK 2797
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
+ + + GTY + A N G + + + + P
Sbjct: 2798 F----HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSP 2837
Score = 31.9 bits (69), Expect = 5.2
Identities = 12/42 (28%), Positives = 22/42 (52%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
+P + + +N+T NE LTC G P P W++ +++
Sbjct: 450 APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREV 491
>Z73899-11|CAA98082.2| 7158|Caenorhabditis elegans Hypothetical
protein ZK617.1b protein.
Length = 7158
Score = 318 bits (782), Expect = 2e-86
Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)
Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
+K+ + + K +C S +WY ++KEI SG +I+ E
Sbjct: 1135 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 1194
Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
D G C T L V E + F+ L + E+ A+L ++N+ A +VW
Sbjct: 1195 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 1254
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
R + I+ ++ EK R L I+ D+ E++ I +D +V V E
Sbjct: 1255 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 1314
Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
+ +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I
Sbjct: 1315 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 1374
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
++D GEY C + + A L V+ + F + L + ++ + D L + D
Sbjct: 1375 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 1432
Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
W++ I KF S TL I K ++ Y + + + V
Sbjct: 1433 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 1492
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
E P + ++ K G + V +Q P + + N K I + K + I
Sbjct: 1493 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 1552
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
A + K + D G + L L N+ G A + + DKP PP P + + +
Sbjct: 1553 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 1612
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N
Sbjct: 1613 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 1672
Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
E +SD E+ Y K + + V+K + EP E+ I G +
Sbjct: 1673 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 1732
Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
+ + W++ G+ T K E++ C DHG+
Sbjct: 1733 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 1785
Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
+ +K + IK + KVG+ I G P PE +W NG L+ +
Sbjct: 1786 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 1844
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
+++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ +
Sbjct: 1845 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 1904
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR
Sbjct: 1905 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 1964
Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
V A N G SE L ++ IK D P D + + I W P K+GG+PI
Sbjct: 1965 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 2023
Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
+Y VE++ + K+WK A I L YQFR+ A N+ G P +K
Sbjct: 2024 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 2083
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
P + + S + T++W GG PI E K KG +
Sbjct: 2084 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 2137
Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
+T+ +EH CI + D +R++ +N+ G + +V L++ PS P P
Sbjct: 2138 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 2192
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L
Sbjct: 2193 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 2250
Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+ TY R+ A N+ G S+ L +D+ K
Sbjct: 2251 KGQTYQFRVKAVNKEGASDALSTDKDTK 2278
Score = 253 bits (619), Expect = 1e-66
Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)
Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
P ++D +E ++K G D +L + P P W ++ K + +
Sbjct: 3268 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 3327
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
+K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP
Sbjct: 3328 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 3387
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD
Sbjct: 3388 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 3447
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
E E + K+ ++ P + + D++ T GG P V
Sbjct: 3448 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3506
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
A ++ A N GE + S + + + + N
Sbjct: 3507 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3566
Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K
Sbjct: 3567 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3626
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG
Sbjct: 3627 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 3686
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L
Sbjct: 3687 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 3743
Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
S+ IV K D P D + V + W P +GG+PI Y VE K + W
Sbjct: 3744 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 3802
Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
A L+ TYQFR+ A N+ G P + P
Sbjct: 3803 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 3862
Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ +K +P+ + T+ + + S H ++
Sbjct: 3863 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 3922
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
D +++I EN G + +V VP P PL+I + +W P
Sbjct: 3923 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 3976
Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
+GG +L Y + D ++ W EVG T K N L Y R+ A N G S+
Sbjct: 3977 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 4034
Query: 2052 PLESDEP 2058
PLE++EP
Sbjct: 4035 PLEAEEP 4041
Score = 251 bits (614), Expect = 5e-66
Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
PKI+ R+ +IK G L VD+ P P W V S + S+
Sbjct: 4150 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 4209
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
+ D+G YKL+++N G + V + D+PS P P + ++ S + W P++
Sbjct: 4210 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 4269
Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+
Sbjct: 4270 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 4329
Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
T E V+ + +P KP + I N+ I++ GG P R D
Sbjct: 4330 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 4385
Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
K + K Y+ +A N G + S + + P
Sbjct: 4386 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 4445
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
+ + + + K G+ ++T P P++ W K G K E TT +T ++
Sbjct: 4446 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 4501
Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
I +RS S I+A N G + + + V DKP PE + +SR + T+ W P
Sbjct: 4502 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 4560
Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+
Sbjct: 4561 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 4619
Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
+ P+VIK D P D V + W P +GGSPI+ Y VE K+
Sbjct: 4620 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 4678
Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
G W + L N TYQFR+ A N G P + +T + P
Sbjct: 4679 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 4738
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
P V + T S L W P +GG+PI YI+E K + WT+ +
Sbjct: 4739 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 4798
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
+N+ EK+E FR+ A N+ G P++ S V +E+ P
Sbjct: 4799 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 4838
Score = 250 bits (612), Expect = 8e-66
Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y
Sbjct: 2399 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 2457
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
L N G + V +L KPS P G + + ++ W PE+ G + I +Y +
Sbjct: 2458 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 2517
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ +
Sbjct: 2518 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 2575
Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
+ P V+KP + + D+ GG P + K + + A ++
Sbjct: 2576 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 2635
Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
++ A N G + S VV + I ED+ KVG
Sbjct: 2636 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 2695
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
I+G P P+V W NG + K I + S + + R S KYTI A+
Sbjct: 2696 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 2754
Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK
Sbjct: 2755 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 2814
Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
+ W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D
Sbjct: 2815 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 2871
Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
P D++ V + W P +GG+PI +Y++E + + +W+ A
Sbjct: 2872 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 2930
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
+ L+ N Y+FR+ A N+ G S P + + P R+ + + + ++
Sbjct: 2931 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 2990
Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
+ P S +P +T + + + ++ K+ + ++ ++ D F I A
Sbjct: 2991 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 3049
Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I
Sbjct: 3050 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 3104
Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
D W+ KV + + L H Y R+ A N G S+PLE+
Sbjct: 3105 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 3156
Score = 243 bits (595), Expect = 1e-63
Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
R+K G + V+ + P P EW +N + +T ++ + LT K D+G
Sbjct: 3574 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 3633
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y
Sbjct: 3634 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 3693
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
VVE QE D W+ + T + L Y+FR AVN S + T + ++
Sbjct: 3694 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 3750
Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
+ P + + + + D+E GG P + +D G ++ A+
Sbjct: 3751 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 3810
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
+ ++ A N G + S G + KP ++ +
Sbjct: 3811 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 3869
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
K G + EG P P W N ++ ++T +S I I R + Y
Sbjct: 3870 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 3929
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E
Sbjct: 3930 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 3989
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K
Sbjct: 3990 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 4047
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
DVP D + + I W P+ NGG+P+ Y VE K++G W
Sbjct: 4048 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 4106
Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
L Y+FR+ A N G S P +D +IT + L P + R + +
Sbjct: 4107 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 4166
Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
++ + + P + + + + +V S + K D ++
Sbjct: 4167 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 4221
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
+ +N +G E +++ PS P PLE+ V + + +W P+ DGGA +
Sbjct: 4222 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 4276
Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP
Sbjct: 4277 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 4334
Score = 242 bits (593), Expect = 2e-63
Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+K G+ + +V P P+ W N K I + K + + + + K +G Y
Sbjct: 2691 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 2749
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+ N G V +N+ + KP+ P P + ++ + W PE+ G I +Y +
Sbjct: 2750 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 2809
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E W+ T ++ +L Y+FR AVN SD ET ++ +
Sbjct: 2810 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 2867
Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
P ++P + T+ + D ++L GG P + + K + + A
Sbjct: 2868 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 2925
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
+ ++ +A N G + S V+ + I + +K K
Sbjct: 2926 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 2985
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + G P P V W+ N+ + N + E S + +K+++R S +T
Sbjct: 2986 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 3045
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE
Sbjct: 3046 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 3105
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K
Sbjct: 3106 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 3165
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
D P D + V + W P +GG+PI +Y VE+K E W
Sbjct: 3166 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 3224
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A + L + Y+FRI A+N+ G P S + + + PP RN +
Sbjct: 3225 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 3283
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
P S +P + E V+ K+ G H ++ D + I
Sbjct: 3284 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 3342
Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
AEN G T V + H PS P PL++ + + +W PE DGGA +
Sbjct: 3343 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 3397
Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E
Sbjct: 3398 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 3452
Score = 235 bits (575), Expect = 3e-61
Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)
Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
+ RIK G+ + L + ++ P P +W N I + S+++ I D
Sbjct: 3866 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 3925
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++
Sbjct: 3926 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 3985
Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
Y+VE + W V + L Y FR AVN S E E
Sbjct: 3986 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 4045
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
+ + P V+KP + DI+ T GG P VT Y KK K + E
Sbjct: 4046 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 4101
Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
++ IA N G + S Q KP I ++ IK
Sbjct: 4102 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 4161
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
K V + G P P W + E + K T+ I KR+ S
Sbjct: 4162 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 4219
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y
Sbjct: 4220 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 4279
Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
+EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K
Sbjct: 4280 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 4338
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
P DN+ + I W P NGGSP+ Y +E K + G+ K
Sbjct: 4339 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 4397
Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
A R+QK TY++R+ A N+ G P S T P +
Sbjct: 4398 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 4454
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
F V +T+ +T SP + I + GK + T S + I +
Sbjct: 4455 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 4505
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
+ D +I A N G + ++++ TV P AP I V + +W
Sbjct: 4506 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 4557
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G
Sbjct: 4558 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 4616
Query: 2049 LSE 2051
LS+
Sbjct: 4617 LSD 4619
Score = 234 bits (572), Expect = 6e-61
Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + +K G+ V V P P +W N ++ + T + ++ L I
Sbjct: 2096 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 2155
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
+D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G
Sbjct: 2156 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 2215
Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T
Sbjct: 2216 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 2274
Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
K+TK ++P ++P K T + + D + + P+ +T Y KK K
Sbjct: 2275 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 2328
Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
+ E ++ ++ A N G E S VV +
Sbjct: 2329 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 2388
Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++
Sbjct: 2389 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 2447
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD
Sbjct: 2448 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 2507
Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
GG + Y IEK + RW+ + T + L EY FRV A N G S+ L
Sbjct: 2508 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 2565
Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
+ I+ K +VP D + V + W + +GG+PI + +E K + +
Sbjct: 2566 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 2623
Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
W+ A + L YQFRI ARN+ GT P D++ P R
Sbjct: 2624 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 2683
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+ + TLK+ +P + K + G+S +I + +
Sbjct: 2684 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 2741
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
K + I+A N G T+S ++ + K + P+ P P+E+ V + W P
Sbjct: 2742 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 2796
Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S
Sbjct: 2797 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 2854
Query: 2051 EPLESD 2056
+PLE++
Sbjct: 2855 DPLETE 2860
Score = 223 bits (545), Expect = 1e-57
Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + IK G ++ V P P W +++ I+ K + L +K++
Sbjct: 2977 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 3036
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G
Sbjct: 3037 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 3096
Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
I YV+E + + W+ + KT + L Y+FR V V+ S+
Sbjct: 3097 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 3153
Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
E + T + +KP K IT + ++L GG P + V +D
Sbjct: 3154 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 3209
Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
+ ++ A N G S V + P
Sbjct: 3210 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 3269
Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
+ N + K K G ++ + + G P P + W G +E+D + ++ + +
Sbjct: 3270 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 3329
Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D
Sbjct: 3330 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 3389
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+
Sbjct: 3390 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 3447
Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
LE+ E I+ K D + D + + W P +GG+PI Y VE++
Sbjct: 3448 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3506
Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
W A + L TYQFR+ A N+ G S P + P
Sbjct: 3507 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3566
Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
R+ V++ TL + +P + + + T I + + ++
Sbjct: 3567 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3626
Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
D ++I A N G + V + +P P PL + + V+ W
Sbjct: 3627 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 3681
Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G
Sbjct: 3682 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 3738
Query: 2050 SEPLESD 2056
S PL SD
Sbjct: 3739 SAPLTSD 3745
Score = 209 bits (510), Expect = 2e-53
Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)
Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
++ ++ G + + + Y P+P + + I + + T ++ +T + +
Sbjct: 4846 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 4905
Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I
Sbjct: 4906 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 4965
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET +
Sbjct: 4966 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 5022
Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
++ + +P +P T+E ++ T GG P Q V R+ + KA
Sbjct: 5023 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 5082
Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
+ N Y + A+N G+ E S + P N + +
Sbjct: 5083 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 5142
Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
+ G+ + P P+V + K NK+ D + + + + I++ + +
Sbjct: 5143 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 5202
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T
Sbjct: 5203 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 5261
Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++
Sbjct: 5262 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 5320
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
+V K +VP+ D+ + W P ++GGS II Y+V+ + +W
Sbjct: 5321 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 5378
Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
AR+ L N ++FRI A+N G S P ++ + PP P +
Sbjct: 5379 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 5438
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
T+ W P +GGS IT Y +E + WT E ++ ++E
Sbjct: 5439 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 5498
Query: 1934 DEIIFRISAENTVGVSLPT 1952
++ FR+ A N G +P+
Sbjct: 5499 NDYEFRVVAINAAGKGIPS 5517
Score = 199 bits (485), Expect = 2e-50
Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
+D + +L + + N ++++ NN G ++ + I D +P PG+P I +
Sbjct: 1943 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 2002
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F
Sbjct: 2003 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 2062
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
R AVN+ SE +E ++ K I + LK+IT + + GG P P
Sbjct: 2063 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 2121
Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
+V W++ ++L+ + T + R Y+ N HG E +
Sbjct: 2122 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 2181
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
+ +P + N ++ D ++ E I Y KL+ + K
Sbjct: 2182 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 2239
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
K + I LK+ + ++ ++A N G S T K YD+P K P ++ +
Sbjct: 2240 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 2298
Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
+ V++EW+PP DGG +T+Y IEK W + V D I L E EY F
Sbjct: 2299 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 2358
Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
RV A N G EA + S +V K P ID E++ + K G
Sbjct: 2359 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 2405
Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
D V + KK W RI+ T + R R G T+ +
Sbjct: 2406 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2465
Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
DK ++ L PS P VS L+W PE +GG+PI +Y IE +
Sbjct: 2466 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 2525
Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
W V G S + + N++ E FR+ A N G S P + + L K+ VP
Sbjct: 2526 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 2582
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
P E+ + V +W P+ DGGAP+ + I +D W E V + +
Sbjct: 2583 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 2639
Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+L E Y RI ARN+ G +P + +
Sbjct: 2640 PNLKEGEEYQFRISARNKAGTGDPSDPSD 2668
Score = 191 bits (465), Expect = 5e-48
Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)
Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
W + ++D +K + S+ K ++R T YT +A + K VEV+
Sbjct: 2421 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 2479
Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
P ++ Y + +D+ V P D + + + + P S++
Sbjct: 2480 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 2536
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
T+ ++ +++R N G +D + N IL K P KP +++ D +
Sbjct: 2537 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 2596
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A
Sbjct: 2597 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 2654
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT
Sbjct: 2655 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 2712
Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
W +GK + +KA EN Y A N +G + + ++ KP
Sbjct: 2713 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 2772
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
K +V D + A ++ PP + + +Y+ D + +
Sbjct: 2773 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 2826
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
+ + L + K+ ++A N+ G S ++ K +D+P +P P +
Sbjct: 2827 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 2885
Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
+ V ++W PPL DGG + +Y IEK RW V T + L N EY FR
Sbjct: 2886 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 2944
Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
V+A N G S+ ++ VI ++ I++ +P +
Sbjct: 2945 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 3004
Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
+ +E G + K ++++ + F I A N G + KI
Sbjct: 3005 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 3061
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
+ T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W
Sbjct: 3062 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 3118
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
V G ++ + E FR++A N G S P E+ L K P AP EI
Sbjct: 3119 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 3177
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ V W P DGGAP+ Y + ++D W +V V + +L E
Sbjct: 3178 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 3237
Query: 2036 TYMIRIYARNEIGLSEPLES 2055
Y RI A+N+ GL +P +S
Sbjct: 3238 KYEFRIRAKNKAGLGDPSDS 3257
Score = 190 bits (463), Expect = 9e-48
Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI
Sbjct: 4586 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 4644
Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N
Sbjct: 4645 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 4704
Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+Y+FR AVN + S +E V K +P V K KN + E + L
Sbjct: 4705 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 4763
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
GG P + + KKL T N ++ IA N GE
Sbjct: 4764 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 4819
Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
E S +V I++ +P+ I+N +DI + G+ + G P +I NGN
Sbjct: 4820 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 4877
Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
EN++ + VI KRS + Y I A+N G + ++ + V D P KP
Sbjct: 4878 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 4936
Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++
Sbjct: 4937 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 4993
Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
L+ N Y FRV A+N G E LE+ + IV K D P E++ + W
Sbjct: 4994 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 5052
Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
+GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N
Sbjct: 5053 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 5112
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
G + IT T P + + + K P + +P +
Sbjct: 5113 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 5172
Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ V + IE + D ++ + EN+ G ++S S+RL+
Sbjct: 5173 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 5224
Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
V P +P IR+ + + W P DGG+P+ Y + D+ + W +V
Sbjct: 5225 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 5283
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
V L + + L +++ Y R+ A + G+SEP E
Sbjct: 5284 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 5317
Score = 183 bits (445), Expect = 1e-45
Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I
Sbjct: 4301 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 4360
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
+I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A
Sbjct: 4361 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 4420
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
VN+ S+++ + ++P + L K + E + +T F PQP +
Sbjct: 4421 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 4478
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
+W ++G K T +++ K A N +GE E + + + KP
Sbjct: 4479 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 4538
Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
+ +H W G E+ YK + + ++ + +
Sbjct: 4539 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 4595
Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
++ L+ ++ I A N G S V V +K +D P P P I + + V++
Sbjct: 4596 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 4654
Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A
Sbjct: 4655 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 4713
Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
N G E SEP+ + ++ P N S +TW ++GG+PI Y
Sbjct: 4714 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 4772
Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
VE K+ G W ++ L Y+FR+ A N G P D + I
Sbjct: 4773 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 4832
Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
+ P N + + T++ P + G PI + + T +V V
Sbjct: 4833 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 4891
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
K D ++ISA N G + V P PT P+ +
Sbjct: 4892 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 4946
Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y
Sbjct: 4947 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 5003
Query: 2040 RIYARNEIGLSEPLESDE 2057
R+ A N+ G+ EPLE+D+
Sbjct: 5004 RVRAENQYGVGEPLETDD 5021
Score = 178 bits (434), Expect = 3e-44
Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D P P KP + + D I+I W+ N G + + Y+VE +E + W T
Sbjct: 4049 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 4108
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S NLK Y FR AVN SD S+ T+ I + + P + + I +
Sbjct: 4109 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 4166
Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
L F G P P TW D + + + YK N
Sbjct: 4167 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 4226
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ GE E V +Q +P + +V D + V+ PP + + N +
Sbjct: 4227 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 4280
Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
++ T S I + +L H ++ + A NT G S S+ V K
Sbjct: 4281 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 4340
Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV
Sbjct: 4341 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 4399
Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
+ ++ + Y +RV+A N G + +S K + P
Sbjct: 4400 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 4459
Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
E + IT P SP D + +EG K + I + +
Sbjct: 4460 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 4513
Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
+I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I
Sbjct: 4514 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 4567
Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S +
Sbjct: 4568 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 4625
Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
V ++ P P+ P EI +N V +W P DGG+P+LGY + W
Sbjct: 4626 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 4684
Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
V V + + L EN TY R+ A N G EP EP P
Sbjct: 4685 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 4732
Score = 176 bits (428), Expect = 2e-43
Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+I+ + ++ +A F E + + RW ++G E+ S+ + K I
Sbjct: 5533 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 5592
Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
+ DAGEY+ EV G+ TA L V+ P + +P IL + Y +
Sbjct: 5593 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 5651
Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
P V ++ + T + D T+ E + EYT ++TT
Sbjct: 5652 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 5711
Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ V P + I T + ++ P + + S +++K +K
Sbjct: 5712 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 5765
Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
+ + + +K + G+ Y+ R+ EN G V + I P PP P
Sbjct: 5766 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 5825
Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
I+++ + + W P + G + Y+VE QE + EW + + NL
Sbjct: 5826 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 5885
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
YR+R +AVN+ +SD +E + + + P + PL ++ E + C
Sbjct: 5886 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 5944
Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
G P+P+ W++ K+L T+K T N+ Y C A N G
Sbjct: 5945 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 6004
Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
T + I+ KP + I + + + G+ + + P E W K+G K+EN+ +
Sbjct: 6005 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 6064
Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I
Sbjct: 6065 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 6123
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y
Sbjct: 6124 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 6180
Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
FR+IA+N G S+ E + P++I
Sbjct: 6181 EFRIIAENKHGQSKPCEPTAPVLI 6204
Score = 171 bits (416), Expect = 5e-42
Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)
Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+++R N GH + VT ++KP P P + +I +S + W+ P G +
Sbjct: 4708 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 4767
Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++
Sbjct: 4768 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 4827
Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
V+ E + P + LK+IT E I++ + GG P+P + + + +
Sbjct: 4828 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 4885
Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
T YK A N +G+ V+ KP I DI
Sbjct: 4886 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 4945
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
Q + W G + I K ++ + +R++ L +
Sbjct: 4946 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 5000
Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
++ + A N G T V +D P P P + E S E++T++W P DG
Sbjct: 5001 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 5059
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
G + Y IEK E + W K A + + + L Y FRV A N G E ++
Sbjct: 5060 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 5119
Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
S PI A P + +P + + +I
Sbjct: 5120 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 5179
Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
+ K I+K + + + N G SD K + P+ P+
Sbjct: 5180 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 5233
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
+ V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + +
Sbjct: 5234 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 5292
Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
+ + + FR+ AE GVS P E V + K+ VP+ P AP +R S W
Sbjct: 5293 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 5351
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N
Sbjct: 5352 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 5409
Query: 2047 IGLSEPLESDE 2057
G S+P E
Sbjct: 5410 AGFSKPSPPSE 5420
Score = 163 bits (396), Expect = 1e-39
Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++
Sbjct: 1647 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 1704
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
+D + W+ PE G + I Y++E +E +W V + + K + Y
Sbjct: 1705 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 1764
Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
+R AVN+ D + + K+ K K +K++ + E I+ G P
Sbjct: 1765 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 1823
Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
P+ W +GK LK ++ + + N G +++ V
Sbjct: 1824 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 1883
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
+ +P DI G + P + ++N +Y K
Sbjct: 1884 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 1943
Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I +
Sbjct: 1944 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 2002
Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
+ + I W+PP DGG + +Y +E +PD W +V V D I L E EY
Sbjct: 2003 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 2060
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
FRV A N G + E + +P+ + W K GG
Sbjct: 2061 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 2118
Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
PI + K +++ + I + ++R+ +N G
Sbjct: 2119 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 2174
Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+
Sbjct: 2175 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 2232
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
W V + H I+ +K+ FR+ A N G S + K+ T
Sbjct: 2233 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 2289
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
++ ++ V W P+ DGGAP+ Y I + W E GKV + I
Sbjct: 2290 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 2349
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
L E Y R+ A N+ G E SD KV+
Sbjct: 2350 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 2379
Score = 142 bits (343), Expect = 3e-33
Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
P PP I + I W P G S I Y VE +E +T W S N+ + +
Sbjct: 5431 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 5490
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
++ L+ + Y FR A+N S + K+ + + V KP T +P N
Sbjct: 5491 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 5548
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
TC G P+P W R+G++L ++++ +E Y
Sbjct: 5549 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 5608
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
N +G + + +Q PVI +D+ GD + G P N +
Sbjct: 5609 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 5665
Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
++ D I + +I I L + +Y SN +G ++ L V P P+G
Sbjct: 5666 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 5725
Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L
Sbjct: 5726 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 5784
Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
EN EY FRV AQN G L SE PI+ + D P + + V ++W
Sbjct: 5785 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 5843
Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
+GG + Y VE ++E +W + L Y++R++A N+ G
Sbjct: 5844 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 5903
Query: 1848 S 1848
S
Sbjct: 5904 S 5904
Score = 132 bits (320), Expect = 2e-30
Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)
Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
K T KL V V++ P K R I+ + + + ++ P+ N + + +++K
Sbjct: 4920 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 4975
Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
+ T +V N DA +++R EN G + +E + I+ D P P
Sbjct: 4976 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 5035
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ +
Sbjct: 5036 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 5095
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
L +Y FR A N + S + + + P + + ++I E +
Sbjct: 5096 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 5153
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
+ F P PKVT+ + K+ K Y + Y N
Sbjct: 5154 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 5213
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
G S + + KP S + I+ + D W+ + G P I K
Sbjct: 5214 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 5270
Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
+ + K +++ + + L + + ++ + A G S V V ++
Sbjct: 5271 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 5330
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D +
Sbjct: 5331 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 5387
Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
+ + L +N E+ FR+IA+N GFS+ + SE +K+ P I
Sbjct: 5388 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 5446
Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
ITW ++GGS I Y VEI++ G W + KL Y+FR+
Sbjct: 5447 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 5506
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A N G +P I I + + S+P+ V E T++
Sbjct: 5507 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 5544
Score = 129 bits (311), Expect = 2e-29
Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ +
Sbjct: 5316 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 5374
Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
WI+ K Q + L+ N + FR A N S S +E ++ P
Sbjct: 5375 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 5434
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
+ K+I + + G K+T Y R+ G L T + Y R
Sbjct: 5435 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 5492
Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
++ +A N G+ S G IQ+ +P I + ED Q + +
Sbjct: 5493 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 5552
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
AV G P P W +NG +L Y + IKE+ + +YT+E SN
Sbjct: 5553 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 5610
Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
G+ + L V P PVI +++ TI L G L K P
Sbjct: 5611 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 5656
Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
+ + ++D D T I + +++ ++ G E S T L+V
Sbjct: 5657 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 5716
Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
P I + ++W P +GGS I Y VE + K +W
Sbjct: 5717 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 5776
Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
I L N Y+FR+ A+NE G P S+ I PP+ P N + +
Sbjct: 5777 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 5836
Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
VTL W P S+GG + YI+E + + W + + + + N+ + + +R+
Sbjct: 5837 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 5896
Query: 1942 AENTVGVS 1949
A N G+S
Sbjct: 5897 AVNDAGLS 5904
Score = 124 bits (299), Expect = 7e-28
Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)
Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
W P +GGSPI +Y K++++ KW K + L + Y+FR+ A
Sbjct: 5249 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 5308
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
+ G S P D + P+QP V + S L+W +P +GGS I Y ++
Sbjct: 5309 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 5367
Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
++ W + + E C + +++ E FRI A+N G S P+ S+ +L
Sbjct: 5368 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 5424
Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
+ P PP + + +G N +W P DGG+ + GYN+ IR+ T+W
Sbjct: 5425 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 5483
Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
+V +F + L E + Y R+ A N G P P K+ GS
Sbjct: 5484 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5531
Score = 99 bits (238), Expect = 2e-20
Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)
Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P I WY++ + I + +N+ +I N D+G Y C A+ G +H
Sbjct: 1155 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 1211
Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
++ K +F+ L + E K +L C+ + WY K I D R II+
Sbjct: 1212 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 1271
Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
+ GR I +D + + V+E F+ ++ +V E D+A
Sbjct: 1272 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 1331
Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+
Sbjct: 1332 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 1391
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
A++ +V+ + I L++ +V + + T + WF++G +I
Sbjct: 1392 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 1450
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+ LKI ++++A Y + + + +TV E
Sbjct: 1451 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 1491
Score = 99.1 bits (236), Expect = 3e-20
Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)
Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ +
Sbjct: 1595 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 1652
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
++++KE E FR+ A N G+S P +SV + VP P ++ V +
Sbjct: 1653 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 1711
Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
+W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A
Sbjct: 1712 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 1771
Query: 2045 NEIGLSEPLESDEPFKV 2061
N+ G +P + +P K+
Sbjct: 1772 NKAGPGDPCDHGKPIKM 1788
Score = 98.3 bits (234), Expect = 5e-20
Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
+S + TL W P ++GGS IT+Y++E + + W VTV +V + + + +
Sbjct: 5729 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 5785
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW
Sbjct: 5786 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 5842
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P DGG L GY + ++ W + +N+ +L + Y R++A N+ G
Sbjct: 5843 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 5902
Query: 2049 LSEPLESDEPFKVIPGEG 2066
LS+ E D+ G G
Sbjct: 5903 LSDLAELDQTLFQASGSG 5920
Score = 94.3 bits (224), Expect = 9e-19
Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)
Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
L D+ +T+ K + L +H ++ + A N G S + ++ +D P
Sbjct: 5762 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 5821
Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
+ P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y
Sbjct: 5822 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 5880
Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
+ L + +Y +RV A N G S+ E + + + A ++ E
Sbjct: 5881 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 5939
Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
F E + GSP +Y+ + + K+ I L+ + ++ A
Sbjct: 5940 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 5998
Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
N GT + T + PP + + T++ P +
Sbjct: 5999 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 6054
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + ++ S I T I N +D +R+ EN+VG T + +V
Sbjct: 6055 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 6108
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K
Sbjct: 6109 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 6167
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
I L Y RI A N+ G S+P E P +IPG+
Sbjct: 6168 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 6207
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
T LDVP I E + W P NGG+ ++ Y VE + W+
Sbjct: 3946 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 4005
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A++ KL Y FR+ A N G S P +++ I P V++
Sbjct: 4006 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 4065
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
+ +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+
Sbjct: 4066 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 4123
Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
A N G S P++ ++ K + P TA +I++ N+ + G P+
Sbjct: 4124 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 4178
Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
P + + + V K ++ F +++ Y +++ +NE+G E
Sbjct: 4179 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 4231
Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
+ F+VI + A E P E ++V
Sbjct: 4232 EAIFEVIVQDRPSAPEGPLEVSDV 4255
Score = 88.6 bits (210), Expect = 4e-17
Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ +
Sbjct: 6582 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 6640
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
+TI + K D+G YT++A+NS G E + V +E PL E K
Sbjct: 6641 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 6693
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
++ R P T++ N +I + +T + G + D D
Sbjct: 6694 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 6753
Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
V+ S S +D + T+ + + V+ TV TK
Sbjct: 6754 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 6805
Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
+S R + + G +I+ + D + + L K T +P F
Sbjct: 6806 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 6865
Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
+L D E + A ++ + ++ W +GE I +++ L I +
Sbjct: 6866 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 6925
Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
DEG+Y C + E A +TV VE + L + VN
Sbjct: 6926 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 6985
Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV
Sbjct: 6986 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 7045
Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
+ +++ V E + RLP + P T+E + E L V W++
Sbjct: 7046 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 7105
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
IE E+ + L I+ +DD Y ++ K
Sbjct: 7106 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 7145
Score = 87.8 bits (208), Expect = 7e-17
Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S
Sbjct: 5946 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 6005
Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
L++ KP P +++ TIE K P ++ + + +NN
Sbjct: 6006 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 6065
Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
+ D+ T I + +RV+ +N VG V T DVP
Sbjct: 6066 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 6119
Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
+D E+V ++W P +GGS + +Y +E ++ G W I+ L
Sbjct: 6120 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 6178
Query: 1834 TYQFRIYARNEIGTSLP 1850
Y+FRI A N+ G S P
Sbjct: 6179 QYEFRIIAENKHGQSKP 6195
Score = 70.5 bits (165), Expect = 1e-11
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
+P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V +
Sbjct: 5719 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 5777
Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
+ + L ENH Y R+ A+NE G+ PL S+ P
Sbjct: 5778 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 5811
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP
Sbjct: 5893 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5952
Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
W CK + GD + I+ D YT +A NS G T A +
Sbjct: 5953 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 6011
Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
++ +P +FI ++ +KG TI+L P W ++ E I +
Sbjct: 6012 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 6065
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ D + L I+N E D G+Y+ V NS G S VT+
Sbjct: 6066 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 6108
Score = 66.9 bits (156), Expect = 1e-10
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ K +G + F C+V P +TW + +K S + Y+ ++ L
Sbjct: 6585 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 6643
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I V +D G +T AKN+ G T E IV ++ H + +
Sbjct: 6644 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 6699
Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
E P F+ + + + + L C L P P I W+ G V ++ + V+
Sbjct: 6700 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 6758
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
S + CS L+I N + GTYTV A N G VL ++T EP P+V
Sbjct: 6759 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 6807
Score = 66.5 bits (155), Expect = 2e-10
Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P+F+ + + G + PEP I WL GE I ++ + +
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 6919
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
L+I++ KK EG Y A N G+ L +K + + +V + L
Sbjct: 6920 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 6979
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
IV GESV A+V G P + W +N + + DG+T S TI D
Sbjct: 6980 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 7037
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
G Y L+ S+G S V E A+PP + R ++ G+
Sbjct: 7038 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 7092
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
++ W+R +E I +E + G +L I NV+ + D G Y
Sbjct: 7093 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 7137
Score = 62.9 bits (146), Expect = 2e-09
Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
E P L G S SA V G P P I W N + + ++ T
Sbjct: 6861 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 6920
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
+ + K DEG Y +A NS G +T A +TV ++P + E L + +
Sbjct: 6921 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 6980
Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
+ G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+
Sbjct: 6981 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 7038
Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
G Y+ V S S + V + + V L S G + +E + ++
Sbjct: 7039 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 7098
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
+W+ ++I + + ++ G D G+ + +VK+++
Sbjct: 7099 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 7146
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
P F +L T G + +F V G P P I W I S F+ Y ATL
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 6921
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
I + D G + C A N+AG + L V + PL + + V
Sbjct: 6922 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 6972
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
+K + V+ G + E R+ PE ++ W+ G+E+ + S++ +
Sbjct: 6973 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 7023
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ + I + G Y + V +G + + + GEK P V S+
Sbjct: 7024 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 7078
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
G S + + T+ W + ++ + + + + G+T + I K + D+G+Y
Sbjct: 7079 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 7137
Query: 804 TLK-AENSEGIAETSAVI 820
K + + IA+ +A +
Sbjct: 7138 VAKVVKEKKAIAKYAAAL 7155
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
VE E D W R + P N Y+ RK R +V+D G D++
Sbjct: 5857 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 5914
Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
E P+I++ L + G TFE E++ RWFK E+ ++ L
Sbjct: 5915 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 5973
Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
G KQ L I D DDA EY+C NS T N ++ + +P
Sbjct: 5974 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 6028
Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
A + ++IP + + W K IE+ KF++ +D K TL I + +D E
Sbjct: 6029 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 6088
Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
Y V+ ++ T + V V PP+
Sbjct: 6089 YRVVVENSVGSDSGTVNVTVADVPEPPR 6116
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/205 (22%), Positives = 79/205 (38%), Gaps = 14/205 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYC 692
P F++KP Q G D+L+EC L A P+P IAW G + P + + +Y
Sbjct: 5 PRFTQKPSIQQTPTG-DLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-----KTGEKEPPQVIEPLKSMIVR 747
+ L I G Y A N+ GE++ I L + P + + +
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKD 123
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK------ALPTKSDGDTHSITI-LKPKKVKDE 800
G +++ +V P W K+ P+ A+ + T+ + ++ D
Sbjct: 124 GGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDA 183
Query: 801 GVYTLKAENSEGIAETSAVITVEEP 825
G Y N +G + + EEP
Sbjct: 184 GQYRCNIRNDQGETNANLALNFEEP 208
Score = 55.2 bits (127), Expect = 5e-07
Identities = 60/241 (24%), Positives = 95/241 (39%), Gaps = 31/241 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS----QDFQMYYDDDN 564
AP F +K + TP G + EC +E P+P I W +++PS Q
Sbjct: 4 APRFTQKPSIQQTPTGDLLM-ECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLY 62
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
ATLVI+E D G + C A+N G +++ L
Sbjct: 63 KATLVIKEPNAGDGGAYKCTARNQLGESNANINL---------------------NFAGA 101
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
D + P+F KP+ D G+ I++EC++ + P W+ G + + AI
Sbjct: 102 GGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMG-GLYHAI 160
Query: 685 ESDM--HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
SD+ Y L+I G Y N +GE + + L + E +P + E +
Sbjct: 161 FSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFE--EPDPSERQERKR 218
Query: 743 S 743
S
Sbjct: 219 S 219
Score = 54.8 bits (126), Expect = 6e-07
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V
Sbjct: 2939 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 2996
Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E
Sbjct: 2997 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 3056
Query: 816 TSAVITV-EEPTEEN 829
+ I V ++PT N
Sbjct: 3057 ATVKINVIDKPTSPN 3071
Score = 53.6 bits (123), Expect = 1e-06
Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y + A N G+++ + + + E P ++ ++ + + ++ +P P
Sbjct: 5893 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5952
Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A +
Sbjct: 5953 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 6010
Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
I + F+ YE ++G+T+ L+ + +W + ++I I +
Sbjct: 6011 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 6070
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
+ D G + +V++ ++ T+ V +PE
Sbjct: 6071 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 6113
Score = 52.8 bits (121), Expect = 3e-06
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
T A S A + + + ++ PP+ + + T + G++ L + +
Sbjct: 349 TTGASASATSATSGGSASSDASRDKYTRPPIVLEASRSQTGRIGGSVVLEVQWQCHSSTI 408
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++ S +Q+F+G +L + + E SG YKC A G+ A V I
Sbjct: 409 IEWYRDGTLVRNSSEYSQSFNGSIAKLQVNKLTEE-KSGLYKCHAKCDYGEGQSSAMVKI 467
Query: 924 ---DVEK--VTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959
DVE+ + K + Y+ EE K+ L+ +T V+ +
Sbjct: 468 EQSDVEEELMKHRKDAEDEYQKEEQKSQTLQAETKKRVARR 508
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
C L V + +E Y V AVN+ G P +K+K + P +K + ++
Sbjct: 1750 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 1808
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
GE++ + G P P W N KP+KA+ I+K + D G +T+
Sbjct: 1809 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1868
Query: 806 KAENSEGIAETSAVITV 822
+NS G +++A +TV
Sbjct: 1869 TLKNSSGSCDSTATVTV 1885
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P V L + G V FEC++ G PRP+ WF+ + + + + D L+
Sbjct: 5923 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 5981
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
I ++ +DA +TC A N++G S+ L ++
Sbjct: 5982 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 6013
Score = 51.6 bits (118), Expect = 6e-06
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
+ S P+V +G P+++E +++ V + E+ IL+ +V G+P PT W K ++ V +
Sbjct: 965 KTSTPLVPSGASGSA--PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVIS 1022
Query: 778 ---LPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEG 812
+DG H++ + K + +DEG YTL EN G
Sbjct: 1023 GGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHG 1061
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
+I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V
Sbjct: 2346 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 2405
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
V G P P W N KPV + + + + +L+ K G+YTL A N+
Sbjct: 2406 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2465
Query: 812 GIAETSA-VITVEEPT 826
G + S VI + +P+
Sbjct: 2466 GSDKHSVEVIVLGKPS 2481
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
I LP E P V K P F C+ G P P W R +
Sbjct: 5515 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 5574
Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
S ++ + D V I+EV+ DAG +T N G ++T L+V+AP
Sbjct: 5575 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 5625
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V
Sbjct: 2051 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 2110
Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P P + W K N+ ++ L + + H+I + D G Y L +NS
Sbjct: 2111 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 2170
Query: 811 EGIAETSAVITV-EEPTEEN 829
G E A +TV + P++ N
Sbjct: 2171 HGADEEKANLTVLDRPSKPN 2190
Score = 49.6 bits (113), Expect = 2e-05
Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
+TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y
Sbjct: 6855 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 6914
Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
+ Y C A N G+ +T + ++ +P++ + +E
Sbjct: 6915 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 6974
Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
KH G+ A ++G P EV+W +NG +L N + +I+ +T I
Sbjct: 6975 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 7033
Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
S + Y +E + GT+ V V +L V + + P
Sbjct: 7034 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 7067
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
P +L + + G A F ++ + + L+ W +G I S+ + + K L+
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6922
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
I D D G+Y C NS + A LTV ++P +N LR+ + + +
Sbjct: 6923 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 6982
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
V + +V W + + + +K ++ D + + I D Y
Sbjct: 6983 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 7042
Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
+ + S L V + P + G ++++ +W
Sbjct: 7043 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 7102
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
S+ I+K + K + L IK VE D GIY
Sbjct: 7103 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 7137
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
+ SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++
Sbjct: 5479 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 5538
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
+ + + + VG P PT W +N + + SDG + TI +
Sbjct: 5539 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 5597
Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825
+ D G YT++ N G +A + V+ P
Sbjct: 5598 I-DAGEYTVEVSNPYGSDTATANLVVQAP 5625
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/121 (26%), Positives = 48/121 (39%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +KA N G + S + P + + F VK T+ V P P
Sbjct: 3534 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 3593
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
I W+ N +S + + +N + T + DSG YK VA+N +GK H V
Sbjct: 3594 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 3653
Query: 923 I 923
I
Sbjct: 3654 I 3654
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
T V+K Y VVAVN+ G T + E P+ L K V+ GE ++
Sbjct: 4406 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 4465
Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G
Sbjct: 4466 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 4522
Query: 813 IAETSAVITV 822
AE + ITV
Sbjct: 4523 EAEANIKITV 4532
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+
Sbjct: 2036 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 2081
Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
P FI + + ITVK T++ ++ P+P + W++ N+ + +T
Sbjct: 2082 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 2139
Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
D E I + S + D G+Y+ NS G A +T+
Sbjct: 2140 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 2182
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
G + EC + P P+ W FKG +E+V ++ + D VL I ++
Sbjct: 5937 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 5991
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
YT A N G S L+IKT P+V P K ++GE++ L P+
Sbjct: 5992 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 6047
Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
W K+ + ++ +D ++ I + +D G Y + ENS G + +
Sbjct: 6048 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 6106
Query: 821 TVEEPTEENAEPPLF 835
TV + EPP F
Sbjct: 6107 TVADV----PEPPRF 6117
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
+ N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L
Sbjct: 3230 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 3289
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
+ V G P PTITW PV++ + T K+ D G Y +KAEN G
Sbjct: 3290 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 3349
Query: 813 IAETSAVITV 822
+TV
Sbjct: 3350 TDTAEVKVTV 3359
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
K+E + + A NS G E S + E+ P IN ++ITV+ TI++ +
Sbjct: 4804 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 4863
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
NP P I + N I +E D E+VIT S+ D+G YK A+N GK
Sbjct: 4864 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 4921
Query: 916 S 916
+
Sbjct: 4922 T 4922
Score = 45.2 bits (102), Expect = 5e-04
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)
Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S
Sbjct: 2707 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 2761
Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
+ I +K+K+ +P IE R G P K N K +P
Sbjct: 2762 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 2821
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
GDTH T+ K D + +KA NSEG + ET I + P + P
Sbjct: 2822 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 2875
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
+ N+K+ +E + + A N+ G + S P + P++ E L V+ G ++
Sbjct: 2639 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 2698
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
+ G P P +TW N K + + + + + PK + K G YT+ A N G
Sbjct: 2699 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 2758
Query: 813 IAETSAVITVE-EPTE 827
+ I V+ +PT+
Sbjct: 2759 TDSVTINIKVKSKPTK 2774
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
N+K E + V+AVN G + S P +I P+++ + + ++ G + L
Sbjct: 4112 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 4171
Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
+G P PT TW + P D + + +I P K D G Y LK +N G
Sbjct: 4172 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 4231
Query: 815 ETSAVITVEE 824
E + V++
Sbjct: 4232 EAIFEVIVQD 4241
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G
Sbjct: 4794 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 4853
Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
E++ I GNP+P I N P+ + T D + I I K D G Y +
Sbjct: 4854 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 4913
Query: 807 AENSEG 812
A N G
Sbjct: 4914 ATNKYG 4919
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P
Sbjct: 3533 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 3592
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
P+I WF + + + + + DN L + D+G + VA N +G
Sbjct: 3593 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 3644
Score = 41.9 bits (94), Expect = 0.005
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ ++A+N G+ + S + N P + N QEI VK L V+ P P
Sbjct: 3241 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 3299
Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ITW + + S N DG+ V + S D+G Y A N G + +V
Sbjct: 3300 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 3357
Query: 922 TI 923
T+
Sbjct: 3358 TV 3359
Score = 41.5 bits (93), Expect = 0.006
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
KN + +AL D T ++ LK +E + + A N G + S N
Sbjct: 2620 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 2676
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
P + + TVK T+K + + P P +TW N + I S+ +N I
Sbjct: 2677 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 2734
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
SG Y A+N G S VTI+++
Sbjct: 2735 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 2767
Score = 41.1 bits (92), Expect = 0.008
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT
Sbjct: 2987 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 3045
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A NA G +T ++ +++ P S +G
Sbjct: 3046 IKAVNANGEDEATVKINVIDKPTSPNG 3072
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++ + + YP+ + W + I+ + F + DD ATL I ED G +
Sbjct: 6033 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 6091
Query: 584 VAKNAAGFASSTTELIV 600
V +N+ G S T + V
Sbjct: 6092 VVENSVGSDSGTVNVTV 6108
Score = 40.3 bits (90), Expect = 0.015
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP V+E +S R G SV+L Q + I W ++ V+ S SI L+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 794 PKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEE 828
K+ +E G+Y A+ G ++SA++ +E+ E
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDVE 473
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP F LR + + C ++G P P I W + + +D
Sbjct: 6702 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 6759
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V +L I +DAGT+T A N G S L V+
Sbjct: 6760 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 6797
Score = 39.9 bits (89), Expect = 0.019
Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P KP+ + C V PEP WL G E+ E+ E+ +
Sbjct: 5530 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 5587
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
Y +K V G YTV N G + L ++ PP + + + + I+ G+
Sbjct: 5588 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 5641
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
V L G + N + + PT + D H + + V++ G Y
Sbjct: 5642 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 5701
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G A T + V E + PL I+ T T+ VT ++
Sbjct: 5702 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 5756
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+S E +T + +++ ++T + E +++ A N G
Sbjct: 5757 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 5801
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
++ E+ + I E ++ V P+ + P + + +TV E T L +V+ +P P+
Sbjct: 954 MRRESVQEILEKTSTPLV--PSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTF 1011
Query: 865 TWYRNNEIISPSETITQNFDGE--NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
W++ + + DG+ + L + S+ D G Y N G S ++
Sbjct: 1012 RWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQ-DEGPYTLTIENVHGTDSADVKLL 1070
Query: 923 IDVEKVTFVKHLQKSYETEEG 943
+ + + + K E++ G
Sbjct: 1071 VTSDNGLDFRAMLKHRESQAG 1091
Score = 39.1 bits (87), Expect = 0.034
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T
Sbjct: 2402 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 2458
Query: 583 CVAKNAAGFASSTTELIV 600
A NA+G + E+IV
Sbjct: 2459 LTATNASGSDKHSVEVIV 2476
Score = 39.1 bits (87), Expect = 0.034
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N
Sbjct: 6727 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 6785
Query: 1652 GTSSVEVTLKVYDKPSKP 1669
G E L V K +P
Sbjct: 6786 GVDVSECVLTVQTKGGEP 6803
Score = 38.7 bits (86), Expect = 0.045
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
++ + E ++K P+ S AP VE + T C+V G P P WF
Sbjct: 956 RESVQEILEKTSTPLVPSGASGS-APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWF 1014
Query: 545 RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + + F+ D ++ L + + +D G +T +N G S+ +L+V
Sbjct: 1015 KGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV--- 1071
Query: 604 LSDHG 608
SD+G
Sbjct: 1072 TSDNG 1076
Score = 38.3 bits (85), Expect = 0.059
Identities = 18/96 (18%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
PP ++ ++Q G E++ ++ W++DG+ ++ S+ + +G KL+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1165 IYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSI 1196
+ + +G Y C+ G + +A++ +E+ +
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDV 472
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 4/126 (3%)
Query: 1255 IRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
IR+ + D + E +L+ ST + PKIV+ + L
Sbjct: 947 IRRSSIDMRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGS 1006
Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCG--HAD 1370
P P W S+ + K D K + +L + K + D G Y L +EN G AD
Sbjct: 1007 PAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSAD 1066
Query: 1371 VEMNVT 1376
V++ VT
Sbjct: 1067 VKLLVT 1072
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
+ +K Q + V A+N+ GE+ S P + P++ + + V+ G+++
Sbjct: 3523 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 3582
Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
V G P P I W N P+ + T D +T + T L K D G Y + A N
Sbjct: 3583 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 3642
Query: 811 EGIAETSAVITV 822
G E + +
Sbjct: 3643 SGKDEHEVDVNI 3654
Score = 37.5 bits (83), Expect = 0.10
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
KS+ D H + KP K V+D E +Y +KA N G + + + A
Sbjct: 1735 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 1794
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P +++ +K TIK ++ P+P W N + + + + + +
Sbjct: 1795 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 1854
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I N DSG + NS+G A VT+
Sbjct: 1855 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 1885
Score = 37.1 bits (82), Expect = 0.14
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT--KEKTSVIRIKELKRSHSSKYTIEAS 1648
++T + G P P W+K ++ + + T KE T + + + + YT+
Sbjct: 998 ILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIE 1057
Query: 1649 NTAGTSSVEVTLKV 1662
N GT S +V L V
Sbjct: 1058 NVHGTDSADVKLLV 1071
Score = 37.1 bits (82), Expect = 0.14
Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y
Sbjct: 6983 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 7041
Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+L + + V V + +K PP + + SS P G ST + +
Sbjct: 7042 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 7088
Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
E++ ++ T +W + ++++KT ++++ V + D + KV+K
Sbjct: 7089 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 7143
Query: 1476 ETK 1478
E K
Sbjct: 7144 EKK 7146
Score = 36.7 bits (81), Expect = 0.18
Identities = 20/91 (21%), Positives = 36/91 (39%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PP +++ R + G V L V +Q EW + +++ S + A L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ K+ +G+YK + + G V I
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKI 467
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+E + + A N G ++ S N +P + + + +T+K +I V+
Sbjct: 2939 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 2998
Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+
Sbjct: 2999 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 3056
Query: 917 HGARVTIDVEKVT 929
++ + ++K T
Sbjct: 3057 ATVKINV-IDKPT 3068
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
L+N + N +LTC G P P + W +DG + + R
Sbjct: 6714 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 6773
Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
Y A ND G + CV+ +Q K
Sbjct: 6774 AGTYTVTATNDLGVDVSECVLTVQTK 6799
Score = 36.3 bits (80), Expect = 0.24
Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 4/104 (3%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY--- 560
E +S P FV K R G+ + EC+V+ P W + + + +
Sbjct: 105 EAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDL 164
Query: 561 -DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
D + L IR DAG + C +N G ++ L E P
Sbjct: 165 GDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFEEP 208
Score = 36.3 bits (80), Expect = 0.24
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++
Sbjct: 2079 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 2138
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
+ + L I D G + KN+ G L +++ P +G
Sbjct: 2139 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 2191
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENI---ELVITNVDSEIDSG 902
G + + + +P P+I W + ++ PS + Q G ++ LVI ++ D G
Sbjct: 19 GDLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAG-DGG 77
Query: 903 DYKCVASNSAGKSS 916
YKC A N G+S+
Sbjct: 78 AYKCTARNQLGESN 91
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PP V W+K+ +L+ +Y + I +K +YT+ A N+ GT V L
Sbjct: 6613 PPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 6672
Query: 1661 KV--YDKPSKPE 1670
V + +P K E
Sbjct: 6673 NVTRHSEPLKFE 6684
Score = 35.5 bits (78), Expect = 0.42
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVK 845
H +T L PKK + V A + S IT + PT + ++I
Sbjct: 5091 HRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLT---RDILAY 5147
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDY 904
K++ +P P +T+ + ISP++ + + + +T SE+ D G Y
Sbjct: 5148 AGERAKILVPFAASPAPKVTFSKGENKISPTDPRVK-VEYSDFLATLTIEKSELTDGGLY 5206
Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
NS G S R+ + V+K +H++
Sbjct: 5207 FVELENSQGSDSASIRLKV-VDKPASPQHIR 5236
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++++ + G P P+ W +K +M + + I D+G FT
Sbjct: 1810 GETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMS-SERGKHIMKIENAVRADSGKFTI 1868
Query: 584 VAKNAAGFASST-TELIVEAPLSDHG 608
KN++G ST T +V P G
Sbjct: 1869 TLKNSSGSCDSTATVTVVGRPTPPKG 1894
Score = 34.7 bits (76), Expect = 0.73
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 499 EKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDF 556
++ ++ +++AP I E L G+T++F ++G P P +TW F I +
Sbjct: 2668 DRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQI 2727
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
+ ++ ++ + + + +G +T A N G S T + V++
Sbjct: 2728 E---NEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKS 2770
Score = 33.5 bits (73), Expect = 1.7
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G V G P P ITW F T + S D ++D ++ D GT+
Sbjct: 3284 GQDFSLNIPVSGEPTPTITWTFEGTPV--ESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3341
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A+N G ++ ++ +++ P S G
Sbjct: 3342 IKAENENGTDTAEVKVTVLDHPSSPRG 3368
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/97 (21%), Positives = 34/97 (35%), Gaps = 2/97 (2%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P + P+ V E +L C++ P P W E++ + H
Sbjct: 977 GSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHT 1036
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
L + + EG YT+ N G S + L +
Sbjct: 1037 V--ALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 1071
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+PP + + V G D L + P P I W F+G + D+ + + E
Sbjct: 3267 VPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTK 3326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
+ + + GTY + A N G + + + + P
Sbjct: 3327 F----HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSP 3366
Score = 31.9 bits (69), Expect = 5.2
Identities = 12/42 (28%), Positives = 22/42 (52%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
+P + + +N+T NE LTC G P P W++ +++
Sbjct: 979 APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREV 1020
Score = 31.5 bits (68), Expect = 6.8
Identities = 34/179 (18%), Positives = 68/179 (37%), Gaps = 15/179 (8%)
Query: 752 VILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGDTHSIT-ILKPKKVKDEGVY 803
+++ + +P+PTI W + + V+ L T G + T ++K D G Y
Sbjct: 21 LLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTL-TPLGGSLYKATLVIKEPNAGDGGAY 79
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPV 861
A N G + + + + A+ P F+ + + I I + +V
Sbjct: 80 KCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSAST 139
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVD----SEIDSGDYKCVASNSAGKSS 916
P W ++ +S F + + ++ S D+G Y+C N G+++
Sbjct: 140 PVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETN 198
>Z73899-10|CAA98081.2| 6839|Caenorhabditis elegans Hypothetical
protein ZK617.1a protein.
Length = 6839
Score = 318 bits (782), Expect = 2e-86
Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)
Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
+K+ + + K +C S +WY ++KEI SG +I+ E
Sbjct: 816 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 875
Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
D G C T L V E + F+ L + E+ A+L ++N+ A +VW
Sbjct: 876 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 935
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
R + I+ ++ EK R L I+ D+ E++ I +D +V V E
Sbjct: 936 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 995
Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
+ +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I
Sbjct: 996 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 1055
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
++D GEY C + + A L V+ + F + L + ++ + D L + D
Sbjct: 1056 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 1113
Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
W++ I KF S TL I K ++ Y + + + V
Sbjct: 1114 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 1173
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
E P + ++ K G + V +Q P + + N K I + K + I
Sbjct: 1174 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 1233
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
A + K + D G + L L N+ G A + + DKP PP P + + +
Sbjct: 1234 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 1293
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N
Sbjct: 1294 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 1353
Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
E +SD E+ Y K + + V+K + EP E+ I G +
Sbjct: 1354 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 1413
Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
+ + W++ G+ T K E++ C DHG+
Sbjct: 1414 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 1466
Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
+ +K + IK + KVG+ I G P PE +W NG L+ +
Sbjct: 1467 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 1525
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
+++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ +
Sbjct: 1526 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 1585
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR
Sbjct: 1586 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 1645
Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
V A N G SE L ++ IK D P D + + I W P K+GG+PI
Sbjct: 1646 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 1704
Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
+Y VE++ + K+WK A I L YQFR+ A N+ G P +K
Sbjct: 1705 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 1764
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
P + + S + T++W GG PI E K KG +
Sbjct: 1765 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 1818
Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
+T+ +EH CI + D +R++ +N+ G + +V L++ PS P P
Sbjct: 1819 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 1873
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L
Sbjct: 1874 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 1931
Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+ TY R+ A N+ G S+ L +D+ K
Sbjct: 1932 KGQTYQFRVKAVNKEGASDALSTDKDTK 1959
Score = 253 bits (619), Expect = 1e-66
Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)
Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
P ++D +E ++K G D +L + P P W ++ K + +
Sbjct: 2949 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 3008
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
+K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP
Sbjct: 3009 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 3068
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD
Sbjct: 3069 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 3128
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
E E + K+ ++ P + + D++ T GG P V
Sbjct: 3129 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3187
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
A ++ A N GE + S + + + + N
Sbjct: 3188 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3247
Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K
Sbjct: 3248 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3307
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG
Sbjct: 3308 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 3367
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L
Sbjct: 3368 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 3424
Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
S+ IV K D P D + V + W P +GG+PI Y VE K + W
Sbjct: 3425 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 3483
Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
A L+ TYQFR+ A N+ G P + P
Sbjct: 3484 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 3543
Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ +K +P+ + T+ + + S H ++
Sbjct: 3544 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 3603
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
D +++I EN G + +V VP P PL+I + +W P
Sbjct: 3604 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 3657
Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
+GG +L Y + D ++ W EVG T K N L Y R+ A N G S+
Sbjct: 3658 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 3715
Query: 2052 PLESDEP 2058
PLE++EP
Sbjct: 3716 PLEAEEP 3722
Score = 251 bits (614), Expect = 5e-66
Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
PKI+ R+ +IK G L VD+ P P W V S + S+
Sbjct: 3831 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 3890
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
+ D+G YKL+++N G + V + D+PS P P + ++ S + W P++
Sbjct: 3891 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 3950
Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+
Sbjct: 3951 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 4010
Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
T E V+ + +P KP + I N+ I++ GG P R D
Sbjct: 4011 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 4066
Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
K + K Y+ +A N G + S + + P
Sbjct: 4067 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 4126
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
+ + + + K G+ ++T P P++ W K G K E TT +T ++
Sbjct: 4127 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 4182
Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
I +RS S I+A N G + + + V DKP PE + +SR + T+ W P
Sbjct: 4183 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 4241
Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+
Sbjct: 4242 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 4300
Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
+ P+VIK D P D V + W P +GGSPI+ Y VE K+
Sbjct: 4301 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 4359
Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
G W + L N TYQFR+ A N G P + +T + P
Sbjct: 4360 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 4419
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
P V + T S L W P +GG+PI YI+E K + WT+ +
Sbjct: 4420 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 4479
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
+N+ EK+E FR+ A N+ G P++ S V +E+ P
Sbjct: 4480 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 4519
Score = 250 bits (612), Expect = 8e-66
Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y
Sbjct: 2080 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 2138
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
L N G + V +L KPS P G + + ++ W PE+ G + I +Y +
Sbjct: 2139 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 2198
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ +
Sbjct: 2199 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 2256
Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
+ P V+KP + + D+ GG P + K + + A ++
Sbjct: 2257 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 2316
Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
++ A N G + S VV + I ED+ KVG
Sbjct: 2317 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 2376
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
I+G P P+V W NG + K I + S + + R S KYTI A+
Sbjct: 2377 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 2435
Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK
Sbjct: 2436 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 2495
Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
+ W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D
Sbjct: 2496 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 2552
Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
P D++ V + W P +GG+PI +Y++E + + +W+ A
Sbjct: 2553 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 2611
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
+ L+ N Y+FR+ A N+ G S P + + P R+ + + + ++
Sbjct: 2612 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 2671
Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
+ P S +P +T + + + ++ K+ + ++ ++ D F I A
Sbjct: 2672 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 2730
Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I
Sbjct: 2731 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 2785
Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
D W+ KV + + L H Y R+ A N G S+PLE+
Sbjct: 2786 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 2837
Score = 243 bits (595), Expect = 1e-63
Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
R+K G + V+ + P P EW +N + +T ++ + LT K D+G
Sbjct: 3255 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 3314
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y
Sbjct: 3315 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 3374
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
VVE QE D W+ + T + L Y+FR AVN S + T + ++
Sbjct: 3375 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 3431
Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
+ P + + + + D+E GG P + +D G ++ A+
Sbjct: 3432 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 3491
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
+ ++ A N G + S G + KP ++ +
Sbjct: 3492 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 3550
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
K G + EG P P W N ++ ++T +S I I R + Y
Sbjct: 3551 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 3610
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E
Sbjct: 3611 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 3670
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K
Sbjct: 3671 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 3728
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
DVP D + + I W P+ NGG+P+ Y VE K++G W
Sbjct: 3729 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 3787
Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
L Y+FR+ A N G S P +D +IT + L P + R + +
Sbjct: 3788 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 3847
Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
++ + + P + + + + +V S + K D ++
Sbjct: 3848 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 3902
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
+ +N +G E +++ PS P PLE+ V + + +W P+ DGGA +
Sbjct: 3903 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 3957
Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP
Sbjct: 3958 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 4015
Score = 242 bits (593), Expect = 2e-63
Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+K G+ + +V P P+ W N K I + K + + + + K +G Y
Sbjct: 2372 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 2430
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+ N G V +N+ + KP+ P P + ++ + W PE+ G I +Y +
Sbjct: 2431 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 2490
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E W+ T ++ +L Y+FR AVN SD ET ++ +
Sbjct: 2491 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 2548
Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
P ++P + T+ + D ++L GG P + + K + + A
Sbjct: 2549 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 2606
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
+ ++ +A N G + S V+ + I + +K K
Sbjct: 2607 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 2666
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + G P P V W+ N+ + N + E S + +K+++R S +T
Sbjct: 2667 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 2726
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE
Sbjct: 2727 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 2786
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K
Sbjct: 2787 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 2846
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
D P D + V + W P +GG+PI +Y VE+K E W
Sbjct: 2847 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 2905
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A + L + Y+FRI A+N+ G P S + + + PP RN +
Sbjct: 2906 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 2964
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
P S +P + E V+ K+ G H ++ D + I
Sbjct: 2965 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 3023
Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
AEN G T V + H PS P PL++ + + +W PE DGGA +
Sbjct: 3024 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 3078
Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E
Sbjct: 3079 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 3133
Score = 235 bits (575), Expect = 3e-61
Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)
Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
+ RIK G+ + L + ++ P P +W N I + S+++ I D
Sbjct: 3547 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 3606
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++
Sbjct: 3607 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 3666
Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
Y+VE + W V + L Y FR AVN S E E
Sbjct: 3667 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 3726
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
+ + P V+KP + DI+ T GG P VT Y KK K + E
Sbjct: 3727 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 3782
Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
++ IA N G + S Q KP I ++ IK
Sbjct: 3783 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 3842
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
K V + G P P W + E + K T+ I KR+ S
Sbjct: 3843 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 3900
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y
Sbjct: 3901 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 3960
Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
+EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K
Sbjct: 3961 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 4019
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
P DN+ + I W P NGGSP+ Y +E K + G+ K
Sbjct: 4020 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 4078
Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
A R+QK TY++R+ A N+ G P S T P +
Sbjct: 4079 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 4135
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
F V +T+ +T SP + I + GK + T S + I +
Sbjct: 4136 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 4186
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
+ D +I A N G + ++++ TV P AP I V + +W
Sbjct: 4187 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 4238
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G
Sbjct: 4239 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 4297
Query: 2049 LSE 2051
LS+
Sbjct: 4298 LSD 4300
Score = 234 bits (572), Expect = 6e-61
Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + +K G+ V V P P +W N ++ + T + ++ L I
Sbjct: 1777 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 1836
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
+D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G
Sbjct: 1837 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 1896
Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T
Sbjct: 1897 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 1955
Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
K+TK ++P ++P K T + + D + + P+ +T Y KK K
Sbjct: 1956 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 2009
Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
+ E ++ ++ A N G E S VV +
Sbjct: 2010 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 2069
Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++
Sbjct: 2070 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 2128
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD
Sbjct: 2129 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 2188
Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
GG + Y IEK + RW+ + T + L EY FRV A N G S+ L
Sbjct: 2189 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 2246
Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
+ I+ K +VP D + V + W + +GG+PI + +E K + +
Sbjct: 2247 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 2304
Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
W+ A + L YQFRI ARN+ GT P D++ P R
Sbjct: 2305 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 2364
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+ + TLK+ +P + K + G+S +I + +
Sbjct: 2365 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 2422
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
K + I+A N G T+S ++ + K + P+ P P+E+ V + W P
Sbjct: 2423 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 2477
Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S
Sbjct: 2478 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 2535
Query: 2051 EPLESD 2056
+PLE++
Sbjct: 2536 DPLETE 2541
Score = 223 bits (545), Expect = 1e-57
Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + IK G ++ V P P W +++ I+ K + L +K++
Sbjct: 2658 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 2717
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G
Sbjct: 2718 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 2777
Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
I YV+E + + W+ + KT + L Y+FR V V+ S+
Sbjct: 2778 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 2834
Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
E + T + +KP K IT + ++L GG P + V +D
Sbjct: 2835 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 2890
Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
+ ++ A N G S V + P
Sbjct: 2891 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 2950
Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
+ N + K K G ++ + + G P P + W G +E+D + ++ + +
Sbjct: 2951 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 3010
Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D
Sbjct: 3011 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 3070
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+
Sbjct: 3071 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 3128
Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
LE+ E I+ K D + D + + W P +GG+PI Y VE++
Sbjct: 3129 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3187
Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
W A + L TYQFR+ A N+ G S P + P
Sbjct: 3188 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3247
Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
R+ V++ TL + +P + + + T I + + ++
Sbjct: 3248 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3307
Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
D ++I A N G + V + +P P PL + + V+ W
Sbjct: 3308 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 3362
Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G
Sbjct: 3363 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 3419
Query: 2050 SEPLESD 2056
S PL SD
Sbjct: 3420 SAPLTSD 3426
Score = 209 bits (510), Expect = 2e-53
Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)
Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
++ ++ G + + + Y P+P + + I + + T ++ +T + +
Sbjct: 4527 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 4586
Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I
Sbjct: 4587 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 4646
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET +
Sbjct: 4647 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 4703
Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
++ + +P +P T+E ++ T GG P Q V R+ + KA
Sbjct: 4704 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 4763
Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
+ N Y + A+N G+ E S + P N + +
Sbjct: 4764 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 4823
Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
+ G+ + P P+V + K NK+ D + + + + I++ + +
Sbjct: 4824 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 4883
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T
Sbjct: 4884 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 4942
Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++
Sbjct: 4943 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 5001
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
+V K +VP+ D+ + W P ++GGS II Y+V+ + +W
Sbjct: 5002 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 5059
Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
AR+ L N ++FRI A+N G S P ++ + PP P +
Sbjct: 5060 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 5119
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
T+ W P +GGS IT Y +E + WT E ++ ++E
Sbjct: 5120 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 5179
Query: 1934 DEIIFRISAENTVGVSLPT 1952
++ FR+ A N G +P+
Sbjct: 5180 NDYEFRVVAINAAGKGIPS 5198
Score = 199 bits (485), Expect = 2e-50
Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
+D + +L + + N ++++ NN G ++ + I D +P PG+P I +
Sbjct: 1624 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 1683
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F
Sbjct: 1684 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 1743
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
R AVN+ SE +E ++ K I + LK+IT + + GG P P
Sbjct: 1744 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 1802
Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
+V W++ ++L+ + T + R Y+ N HG E +
Sbjct: 1803 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 1862
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
+ +P + N ++ D ++ E I Y KL+ + K
Sbjct: 1863 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 1920
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
K + I LK+ + ++ ++A N G S T K YD+P K P ++ +
Sbjct: 1921 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 1979
Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
+ V++EW+PP DGG +T+Y IEK W + V D I L E EY F
Sbjct: 1980 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 2039
Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
RV A N G EA + S +V K P ID E++ + K G
Sbjct: 2040 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 2086
Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
D V + KK W RI+ T + R R G T+ +
Sbjct: 2087 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2146
Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
DK ++ L PS P VS L+W PE +GG+PI +Y IE +
Sbjct: 2147 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 2206
Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
W V G S + + N++ E FR+ A N G S P + + L K+ VP
Sbjct: 2207 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 2263
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
P E+ + V +W P+ DGGAP+ + I +D W E V + +
Sbjct: 2264 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 2320
Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+L E Y RI ARN+ G +P + +
Sbjct: 2321 PNLKEGEEYQFRISARNKAGTGDPSDPSD 2349
Score = 191 bits (465), Expect = 5e-48
Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)
Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
W + ++D +K + S+ K ++R T YT +A + K VEV+
Sbjct: 2102 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 2160
Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
P ++ Y + +D+ V P D + + + + P S++
Sbjct: 2161 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 2217
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
T+ ++ +++R N G +D + N IL K P KP +++ D +
Sbjct: 2218 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 2277
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A
Sbjct: 2278 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 2335
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT
Sbjct: 2336 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 2393
Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
W +GK + +KA EN Y A N +G + + ++ KP
Sbjct: 2394 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 2453
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
K +V D + A ++ PP + + +Y+ D + +
Sbjct: 2454 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 2507
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
+ + L + K+ ++A N+ G S ++ K +D+P +P P +
Sbjct: 2508 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 2566
Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
+ V ++W PPL DGG + +Y IEK RW V T + L N EY FR
Sbjct: 2567 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 2625
Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
V+A N G S+ ++ VI ++ I++ +P +
Sbjct: 2626 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 2685
Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
+ +E G + K ++++ + F I A N G + KI
Sbjct: 2686 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 2742
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
+ T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W
Sbjct: 2743 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 2799
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
V G ++ + E FR++A N G S P E+ L K P AP EI
Sbjct: 2800 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 2858
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ V W P DGGAP+ Y + ++D W +V V + +L E
Sbjct: 2859 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 2918
Query: 2036 TYMIRIYARNEIGLSEPLES 2055
Y RI A+N+ GL +P +S
Sbjct: 2919 KYEFRIRAKNKAGLGDPSDS 2938
Score = 190 bits (463), Expect = 9e-48
Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI
Sbjct: 4267 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 4325
Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N
Sbjct: 4326 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 4385
Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+Y+FR AVN + S +E V K +P V K KN + E + L
Sbjct: 4386 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 4444
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
GG P + + KKL T N ++ IA N GE
Sbjct: 4445 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 4500
Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
E S +V I++ +P+ I+N +DI + G+ + G P +I NGN
Sbjct: 4501 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 4558
Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
EN++ + VI KRS + Y I A+N G + ++ + V D P KP
Sbjct: 4559 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 4617
Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++
Sbjct: 4618 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 4674
Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
L+ N Y FRV A+N G E LE+ + IV K D P E++ + W
Sbjct: 4675 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 4733
Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
+GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N
Sbjct: 4734 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 4793
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
G + IT T P + + + K P + +P +
Sbjct: 4794 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 4853
Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ V + IE + D ++ + EN+ G ++S S+RL+
Sbjct: 4854 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 4905
Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
V P +P IR+ + + W P DGG+P+ Y + D+ + W +V
Sbjct: 4906 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 4964
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
V L + + L +++ Y R+ A + G+SEP E
Sbjct: 4965 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 4998
Score = 183 bits (445), Expect = 1e-45
Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I
Sbjct: 3982 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 4041
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
+I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A
Sbjct: 4042 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 4101
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
VN+ S+++ + ++P + L K + E + +T F PQP +
Sbjct: 4102 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 4159
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
+W ++G K T +++ K A N +GE E + + + KP
Sbjct: 4160 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 4219
Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
+ +H W G E+ YK + + ++ + +
Sbjct: 4220 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 4276
Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
++ L+ ++ I A N G S V V +K +D P P P I + + V++
Sbjct: 4277 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 4335
Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A
Sbjct: 4336 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 4394
Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
N G E SEP+ + ++ P N S +TW ++GG+PI Y
Sbjct: 4395 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 4453
Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
VE K+ G W ++ L Y+FR+ A N G P D + I
Sbjct: 4454 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 4513
Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
+ P N + + T++ P + G PI + + T +V V
Sbjct: 4514 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 4572
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
K D ++ISA N G + V P PT P+ +
Sbjct: 4573 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 4627
Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y
Sbjct: 4628 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 4684
Query: 2040 RIYARNEIGLSEPLESDE 2057
R+ A N+ G+ EPLE+D+
Sbjct: 4685 RVRAENQYGVGEPLETDD 4702
Score = 178 bits (434), Expect = 3e-44
Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D P P KP + + D I+I W+ N G + + Y+VE +E + W T
Sbjct: 3730 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 3789
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S NLK Y FR AVN SD S+ T+ I + + P + + I +
Sbjct: 3790 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 3847
Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
L F G P P TW D + + + YK N
Sbjct: 3848 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 3907
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ GE E V +Q +P + +V D + V+ PP + + N +
Sbjct: 3908 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 3961
Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
++ T S I + +L H ++ + A NT G S S+ V K
Sbjct: 3962 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 4021
Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV
Sbjct: 4022 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 4080
Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
+ ++ + Y +RV+A N G + +S K + P
Sbjct: 4081 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 4140
Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
E + IT P SP D + +EG K + I + +
Sbjct: 4141 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 4194
Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
+I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I
Sbjct: 4195 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 4248
Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S +
Sbjct: 4249 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 4306
Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
V ++ P P+ P EI +N V +W P DGG+P+LGY + W
Sbjct: 4307 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 4365
Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
V V + + L EN TY R+ A N G EP EP P
Sbjct: 4366 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 4413
Score = 176 bits (428), Expect = 2e-43
Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+I+ + ++ +A F E + + RW ++G E+ S+ + K I
Sbjct: 5214 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 5273
Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
+ DAGEY+ EV G+ TA L V+ P + +P IL + Y +
Sbjct: 5274 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 5332
Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
P V ++ + T + D T+ E + EYT ++TT
Sbjct: 5333 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 5392
Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ V P + I T + ++ P + + S +++K +K
Sbjct: 5393 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 5446
Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
+ + + +K + G+ Y+ R+ EN G V + I P PP P
Sbjct: 5447 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 5506
Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
I+++ + + W P + G + Y+VE QE + EW + + NL
Sbjct: 5507 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 5566
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
YR+R +AVN+ +SD +E + + + P + PL ++ E + C
Sbjct: 5567 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 5625
Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
G P+P+ W++ K+L T+K T N+ Y C A N G
Sbjct: 5626 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 5685
Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
T + I+ KP + I + + + G+ + + P E W K+G K+EN+ +
Sbjct: 5686 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 5745
Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I
Sbjct: 5746 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 5804
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y
Sbjct: 5805 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 5861
Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
FR+IA+N G S+ E + P++I
Sbjct: 5862 EFRIIAENKHGQSKPCEPTAPVLI 5885
Score = 171 bits (416), Expect = 5e-42
Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)
Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+++R N GH + VT ++KP P P + +I +S + W+ P G +
Sbjct: 4389 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 4448
Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++
Sbjct: 4449 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 4508
Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
V+ E + P + LK+IT E I++ + GG P+P + + + +
Sbjct: 4509 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 4566
Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
T YK A N +G+ V+ KP I DI
Sbjct: 4567 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 4626
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
Q + W G + I K ++ + +R++ L +
Sbjct: 4627 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 4681
Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
++ + A N G T V +D P P P + E S E++T++W P DG
Sbjct: 4682 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 4740
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
G + Y IEK E + W K A + + + L Y FRV A N G E ++
Sbjct: 4741 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 4800
Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
S PI A P + +P + + +I
Sbjct: 4801 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 4860
Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
+ K I+K + + + N G SD K + P+ P+
Sbjct: 4861 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 4914
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
+ V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + +
Sbjct: 4915 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 4973
Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
+ + + FR+ AE GVS P E V + K+ VP+ P AP +R S W
Sbjct: 4974 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 5032
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N
Sbjct: 5033 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 5090
Query: 2047 IGLSEPLESDE 2057
G S+P E
Sbjct: 5091 AGFSKPSPPSE 5101
Score = 163 bits (396), Expect = 1e-39
Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++
Sbjct: 1328 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 1385
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
+D + W+ PE G + I Y++E +E +W V + + K + Y
Sbjct: 1386 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 1445
Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
+R AVN+ D + + K+ K K +K++ + E I+ G P
Sbjct: 1446 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 1504
Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
P+ W +GK LK ++ + + N G +++ V
Sbjct: 1505 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 1564
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
+ +P DI G + P + ++N +Y K
Sbjct: 1565 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 1624
Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I +
Sbjct: 1625 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 1683
Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
+ + I W+PP DGG + +Y +E +PD W +V V D I L E EY
Sbjct: 1684 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 1741
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
FRV A N G + E + +P+ + W K GG
Sbjct: 1742 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 1799
Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
PI + K +++ + I + ++R+ +N G
Sbjct: 1800 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 1855
Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+
Sbjct: 1856 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 1913
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
W V + H I+ +K+ FR+ A N G S + K+ T
Sbjct: 1914 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 1970
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
++ ++ V W P+ DGGAP+ Y I + W E GKV + I
Sbjct: 1971 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 2030
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
L E Y R+ A N+ G E SD KV+
Sbjct: 2031 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 2060
Score = 142 bits (343), Expect = 3e-33
Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
P PP I + I W P G S I Y VE +E +T W S N+ + +
Sbjct: 5112 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 5171
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
++ L+ + Y FR A+N S + K+ + + V KP T +P N
Sbjct: 5172 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 5229
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
TC G P+P W R+G++L ++++ +E Y
Sbjct: 5230 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 5289
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
N +G + + +Q PVI +D+ GD + G P N +
Sbjct: 5290 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 5346
Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
++ D I + +I I L + +Y SN +G ++ L V P P+G
Sbjct: 5347 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 5406
Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L
Sbjct: 5407 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 5465
Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
EN EY FRV AQN G L SE PI+ + D P + + V ++W
Sbjct: 5466 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 5524
Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
+GG + Y VE ++E +W + L Y++R++A N+ G
Sbjct: 5525 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 5584
Query: 1848 S 1848
S
Sbjct: 5585 S 5585
Score = 132 bits (320), Expect = 2e-30
Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)
Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
K T KL V V++ P K R I+ + + + ++ P+ N + + +++K
Sbjct: 4601 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 4656
Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
+ T +V N DA +++R EN G + +E + I+ D P P
Sbjct: 4657 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 4716
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ +
Sbjct: 4717 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 4776
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
L +Y FR A N + S + + + P + + ++I E +
Sbjct: 4777 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 4834
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
+ F P PKVT+ + K+ K Y + Y N
Sbjct: 4835 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 4894
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
G S + + KP S + I+ + D W+ + G P I K
Sbjct: 4895 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 4951
Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
+ + K +++ + + L + + ++ + A G S V V ++
Sbjct: 4952 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 5011
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D +
Sbjct: 5012 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 5068
Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
+ + L +N E+ FR+IA+N GFS+ + SE +K+ P I
Sbjct: 5069 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 5127
Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
ITW ++GGS I Y VEI++ G W + KL Y+FR+
Sbjct: 5128 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 5187
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A N G +P I I + + S+P+ V E T++
Sbjct: 5188 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 5225
Score = 129 bits (311), Expect = 2e-29
Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ +
Sbjct: 4997 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 5055
Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
WI+ K Q + L+ N + FR A N S S +E ++ P
Sbjct: 5056 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 5115
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
+ K+I + + G K+T Y R+ G L T + Y R
Sbjct: 5116 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 5173
Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
++ +A N G+ S G IQ+ +P I + ED Q + +
Sbjct: 5174 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 5233
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
AV G P P W +NG +L Y + IKE+ + +YT+E SN
Sbjct: 5234 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 5291
Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
G+ + L V P PVI +++ TI L G L K P
Sbjct: 5292 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 5337
Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
+ + ++D D T I + +++ ++ G E S T L+V
Sbjct: 5338 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 5397
Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
P I + ++W P +GGS I Y VE + K +W
Sbjct: 5398 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 5457
Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
I L N Y+FR+ A+NE G P S+ I PP+ P N + +
Sbjct: 5458 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 5517
Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
VTL W P S+GG + YI+E + + W + + + + N+ + + +R+
Sbjct: 5518 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 5577
Query: 1942 AENTVGVS 1949
A N G+S
Sbjct: 5578 AVNDAGLS 5585
Score = 124 bits (299), Expect = 7e-28
Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)
Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
W P +GGSPI +Y K++++ KW K + L + Y+FR+ A
Sbjct: 4930 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 4989
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
+ G S P D + P+QP V + S L+W +P +GGS I Y ++
Sbjct: 4990 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 5048
Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
++ W + + E C + +++ E FRI A+N G S P+ S+ +L
Sbjct: 5049 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 5105
Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
+ P PP + + +G N +W P DGG+ + GYN+ IR+ T+W
Sbjct: 5106 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 5164
Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
+V +F + L E + Y R+ A N G P P K+ GS
Sbjct: 5165 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5212
Score = 99 bits (238), Expect = 2e-20
Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)
Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P I WY++ + I + +N+ +I N D+G Y C A+ G +H
Sbjct: 836 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 892
Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
++ K +F+ L + E K +L C+ + WY K I D R II+
Sbjct: 893 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 952
Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
+ GR I +D + + V+E F+ ++ +V E D+A
Sbjct: 953 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 1012
Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+
Sbjct: 1013 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 1072
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
A++ +V+ + I L++ +V + + T + WF++G +I
Sbjct: 1073 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 1131
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+ LKI ++++A Y + + + +TV E
Sbjct: 1132 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 1172
Score = 99.1 bits (236), Expect = 3e-20
Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)
Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ +
Sbjct: 1276 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 1333
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
++++KE E FR+ A N G+S P +SV + VP P ++ V +
Sbjct: 1334 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 1392
Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
+W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A
Sbjct: 1393 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 1452
Query: 2045 NEIGLSEPLESDEPFKV 2061
N+ G +P + +P K+
Sbjct: 1453 NKAGPGDPCDHGKPIKM 1469
Score = 98.3 bits (234), Expect = 5e-20
Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
+S + TL W P ++GGS IT+Y++E + + W VTV +V + + + +
Sbjct: 5410 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 5466
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW
Sbjct: 5467 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 5523
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P DGG L GY + ++ W + +N+ +L + Y R++A N+ G
Sbjct: 5524 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 5583
Query: 2049 LSEPLESDEPFKVIPGEG 2066
LS+ E D+ G G
Sbjct: 5584 LSDLAELDQTLFQASGSG 5601
Score = 94.3 bits (224), Expect = 9e-19
Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)
Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
L D+ +T+ K + L +H ++ + A N G S + ++ +D P
Sbjct: 5443 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 5502
Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
+ P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y
Sbjct: 5503 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 5561
Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
+ L + +Y +RV A N G S+ E + + + A ++ E
Sbjct: 5562 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 5620
Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
F E + GSP +Y+ + + K+ I L+ + ++ A
Sbjct: 5621 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 5679
Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
N GT + T + PP + + T++ P +
Sbjct: 5680 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 5735
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + ++ S I T I N +D +R+ EN+VG T + +V
Sbjct: 5736 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 5789
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K
Sbjct: 5790 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 5848
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
I L Y RI A N+ G S+P E P +IPG+
Sbjct: 5849 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 5888
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
T LDVP I E + W P NGG+ ++ Y VE + W+
Sbjct: 3627 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 3686
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A++ KL Y FR+ A N G S P +++ I P V++
Sbjct: 3687 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 3746
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
+ +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+
Sbjct: 3747 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 3804
Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
A N G S P++ ++ K + P TA +I++ N+ + G P+
Sbjct: 3805 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 3859
Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
P + + + V K ++ F +++ Y +++ +NE+G E
Sbjct: 3860 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 3912
Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
+ F+VI + A E P E ++V
Sbjct: 3913 EAIFEVIVQDRPSAPEGPLEVSDV 3936
Score = 88.6 bits (210), Expect = 4e-17
Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ +
Sbjct: 6263 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 6321
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
+TI + K D+G YT++A+NS G E + V +E PL E K
Sbjct: 6322 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 6374
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
++ R P T++ N +I + +T + G + D D
Sbjct: 6375 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 6434
Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
V+ S S +D + T+ + + V+ TV TK
Sbjct: 6435 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 6486
Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
+S R + + G +I+ + D + + L K T +P F
Sbjct: 6487 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 6546
Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
+L D E + A ++ + ++ W +GE I +++ L I +
Sbjct: 6547 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 6606
Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
DEG+Y C + E A +TV VE + L + VN
Sbjct: 6607 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 6666
Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV
Sbjct: 6667 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 6726
Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
+ +++ V E + RLP + P T+E + E L V W++
Sbjct: 6727 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 6786
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
IE E+ + L I+ +DD Y ++ K
Sbjct: 6787 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 6826
Score = 87.8 bits (208), Expect = 7e-17
Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S
Sbjct: 5627 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 5686
Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
L++ KP P +++ TIE K P ++ + + +NN
Sbjct: 5687 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5746
Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
+ D+ T I + +RV+ +N VG V T DVP
Sbjct: 5747 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 5800
Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
+D E+V ++W P +GGS + +Y +E ++ G W I+ L
Sbjct: 5801 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 5859
Query: 1834 TYQFRIYARNEIGTSLP 1850
Y+FRI A N+ G S P
Sbjct: 5860 QYEFRIIAENKHGQSKP 5876
Score = 70.5 bits (165), Expect = 1e-11
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
+P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V +
Sbjct: 5400 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 5458
Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
+ + L ENH Y R+ A+NE G+ PL S+ P
Sbjct: 5459 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 5492
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP
Sbjct: 5574 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5633
Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
W CK + GD + I+ D YT +A NS G T A +
Sbjct: 5634 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 5692
Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
++ +P +FI ++ +KG TI+L P W ++ E I +
Sbjct: 5693 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5746
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ D + L I+N E D G+Y+ V NS G S VT+
Sbjct: 5747 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 5789
Score = 66.9 bits (156), Expect = 1e-10
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ K +G + F C+V P +TW + +K S + Y+ ++ L
Sbjct: 6266 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 6324
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I V +D G +T AKN+ G T E IV ++ H + +
Sbjct: 6325 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 6380
Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
E P F+ + + + + L C L P P I W+ G V ++ + V+
Sbjct: 6381 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 6439
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
S + CS L+I N + GTYTV A N G VL ++T EP P+V
Sbjct: 6440 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 6488
Score = 66.5 bits (155), Expect = 2e-10
Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P+F+ + + G + PEP I WL GE I ++ + +
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 6600
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
L+I++ KK EG Y A N G+ L +K + + +V + L
Sbjct: 6601 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 6660
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
IV GESV A+V G P + W +N + + DG+T S TI D
Sbjct: 6661 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 6718
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
G Y L+ S+G S V E A+PP + R ++ G+
Sbjct: 6719 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 6773
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
++ W+R +E I +E + G +L I NV+ + D G Y
Sbjct: 6774 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 6818
Score = 62.9 bits (146), Expect = 2e-09
Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
E P L G S SA V G P P I W N + + ++ T
Sbjct: 6542 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 6601
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
+ + K DEG Y +A NS G +T A +TV ++P + E L + +
Sbjct: 6602 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 6661
Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
+ G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+
Sbjct: 6662 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 6719
Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
G Y+ V S S + V + + V L S G + +E + ++
Sbjct: 6720 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 6779
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
+W+ ++I + + ++ G D G+ + +VK+++
Sbjct: 6780 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 6827
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
P F +L T G + +F V G P P I W I S F+ Y ATL
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 6602
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
I + D G + C A N+AG + L V + PL + + V
Sbjct: 6603 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 6653
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
+K + V+ G + E R+ PE ++ W+ G+E+ + S++ +
Sbjct: 6654 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 6704
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ + I + G Y + V +G + + + GEK P V S+
Sbjct: 6705 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 6759
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
G S + + T+ W + ++ + + + + G+T + I K + D+G+Y
Sbjct: 6760 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 6818
Query: 804 TLK-AENSEGIAETSAVI 820
K + + IA+ +A +
Sbjct: 6819 VAKVVKEKKAIAKYAAAL 6836
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
VE E D W R + P N Y+ RK R +V+D G D++
Sbjct: 5538 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 5595
Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
E P+I++ L + G TFE E++ RWFK E+ ++ L
Sbjct: 5596 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 5654
Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
G KQ L I D DDA EY+C NS T N ++ + +P
Sbjct: 5655 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 5709
Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
A + ++IP + + W K IE+ KF++ +D K TL I + +D E
Sbjct: 5710 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 5769
Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
Y V+ ++ T + V V PP+
Sbjct: 5770 YRVVVENSVGSDSGTVNVTVADVPEPPR 5797
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/205 (22%), Positives = 79/205 (38%), Gaps = 14/205 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYC 692
P F++KP Q G D+L+EC L A P+P IAW G + P + + +Y
Sbjct: 5 PRFTQKPSIQQTPTG-DLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-----KTGEKEPPQVIEPLKSMIVR 747
+ L I G Y A N+ GE++ I L + P + + +
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKD 123
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK------ALPTKSDGDTHSITI-LKPKKVKDE 800
G +++ +V P W K+ P+ A+ + T+ + ++ D
Sbjct: 124 GGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDA 183
Query: 801 GVYTLKAENSEGIAETSAVITVEEP 825
G Y N +G + + EEP
Sbjct: 184 GQYRCNIRNDQGETNANLALNFEEP 208
Score = 55.6 bits (128), Expect = 4e-07
Identities = 91/405 (22%), Positives = 154/405 (38%), Gaps = 40/405 (9%)
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
T A S A + + + ++ PP+ + + T + G++ L + +
Sbjct: 349 TTGASASATSATSGGSASSDASRDKYTRPPIVLEASRSQTGRIGGSVVLEVQWQCHSSTI 408
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++ S +Q+F+G +L + + E SG YKC A G+ A V I
Sbjct: 409 IEWYRDGTLVRNSSEYSQSFNGSIAKLQVNKLTEE-KSGLYKCHAKCDYGEGQSSAMVKI 467
Query: 924 ---DVEK--VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE 978
DVE+ + K + Y+ EE K+ L+ +T V+ + K + + E
Sbjct: 468 EQSDVEEELMKHRKDAEDEYQKEEQKSQTLQAETKKRVARRSKSKSKSPAPQAKKSTTSE 527
Query: 979 -GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAI 1035
GR V D+E+ + TIPE R+ +V E D
Sbjct: 528 SGRQEASEVEHKRSSSVRP----DPDEESQLDEIPSSGLTIPEERRRELLGQVGESD--- 580
Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE-----GEYSCI 1090
E++ +++ G KP++ D K+ I + N S DE S
Sbjct: 581 --DEVSESISELPSFAGG---KPRRKTDDKPKKVSIAPV-STNKSSDDEPSTPRRRSSID 634
Query: 1091 LRDESCTAEVTVVELP----------PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRW 1139
+R ES + P P+I+ +N V + A +++ A RW
Sbjct: 635 MRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRW 694
Query: 1140 FKDGSEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGN 1182
FK E+ + DGK+ L + C D G Y+ + N
Sbjct: 695 FKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIEN 739
Score = 55.2 bits (127), Expect = 5e-07
Identities = 60/241 (24%), Positives = 95/241 (39%), Gaps = 31/241 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS----QDFQMYYDDDN 564
AP F +K + TP G + EC +E P+P I W +++PS Q
Sbjct: 4 APRFTQKPSIQQTPTGDLLM-ECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLY 62
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
ATLVI+E D G + C A+N G +++ L
Sbjct: 63 KATLVIKEPNAGDGGAYKCTARNQLGESNANINL---------------------NFAGA 101
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
D + P+F KP+ D G+ I++EC++ + P W+ G + + AI
Sbjct: 102 GGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMG-GLYHAI 160
Query: 685 ESDM--HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
SD+ Y L+I G Y N +GE + + L + E +P + E +
Sbjct: 161 FSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFE--EPDPSERQERKR 218
Query: 743 S 743
S
Sbjct: 219 S 219
Score = 54.8 bits (126), Expect = 6e-07
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V
Sbjct: 2620 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 2677
Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E
Sbjct: 2678 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 2737
Query: 816 TSAVITV-EEPTEEN 829
+ I V ++PT N
Sbjct: 2738 ATVKINVIDKPTSPN 2752
Score = 53.6 bits (123), Expect = 1e-06
Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y + A N G+++ + + + E P ++ ++ + + ++ +P P
Sbjct: 5574 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5633
Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A +
Sbjct: 5634 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 5691
Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
I + F+ YE ++G+T+ L+ + +W + ++I I +
Sbjct: 5692 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 5751
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
+ D G + +V++ ++ T+ V +PE
Sbjct: 5752 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 5794
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
C L V + +E Y V AVN+ G P +K+K + P +K + ++
Sbjct: 1431 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 1489
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
GE++ + G P P W N KP+KA+ I+K + D G +T+
Sbjct: 1490 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1549
Query: 806 KAENSEGIAETSAVITV 822
+NS G +++A +TV
Sbjct: 1550 TLKNSSGSCDSTATVTV 1566
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P V L + G V FEC++ G PRP+ WF+ + + + + D L+
Sbjct: 5604 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 5662
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
I ++ +DA +TC A N++G S+ L ++
Sbjct: 5663 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 5694
Score = 51.6 bits (118), Expect = 6e-06
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
+ S P+V +G P+++E +++ V + E+ IL+ +V G+P PT W K ++ V +
Sbjct: 646 KTSTPLVPSGASGSA--PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVIS 703
Query: 778 ---LPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEG 812
+DG H++ + K + +DEG YTL EN G
Sbjct: 704 GGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHG 742
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
+I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V
Sbjct: 2027 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 2086
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
V G P P W N KPV + + + + +L+ K G+YTL A N+
Sbjct: 2087 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2146
Query: 812 GIAETSA-VITVEEPT 826
G + S VI + +P+
Sbjct: 2147 GSDKHSVEVIVLGKPS 2162
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
I LP E P V K P F C+ G P P W R +
Sbjct: 5196 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 5255
Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
S ++ + D V I+EV+ DAG +T N G ++T L+V+AP
Sbjct: 5256 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 5306
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V
Sbjct: 1732 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 1791
Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P P + W K N+ ++ L + + H+I + D G Y L +NS
Sbjct: 1792 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 1851
Query: 811 EGIAETSAVITV-EEPTEEN 829
G E A +TV + P++ N
Sbjct: 1852 HGADEEKANLTVLDRPSKPN 1871
Score = 49.6 bits (113), Expect = 2e-05
Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
+TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y
Sbjct: 6536 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 6595
Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
+ Y C A N G+ +T + ++ +P++ + +E
Sbjct: 6596 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 6655
Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
KH G+ A ++G P EV+W +NG +L N + +I+ +T I
Sbjct: 6656 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 6714
Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
S + Y +E + GT+ V V +L V + + P
Sbjct: 6715 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 6748
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
P +L + + G A F ++ + + L+ W +G I S+ + + K L+
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6603
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
I D D G+Y C NS + A LTV ++P +N LR+ + + +
Sbjct: 6604 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 6663
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
V + +V W + + + +K ++ D + + I D Y
Sbjct: 6664 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 6723
Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
+ + S L V + P + G ++++ +W
Sbjct: 6724 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 6783
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
S+ I+K + K + L IK VE D GIY
Sbjct: 6784 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 6818
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
+ SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++
Sbjct: 5160 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 5219
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
+ + + + VG P PT W +N + + SDG + TI +
Sbjct: 5220 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 5278
Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825
+ D G YT++ N G +A + V+ P
Sbjct: 5279 I-DAGEYTVEVSNPYGSDTATANLVVQAP 5306
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/121 (26%), Positives = 48/121 (39%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +KA N G + S + P + + F VK T+ V P P
Sbjct: 3215 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 3274
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
I W+ N +S + + +N + T + DSG YK VA+N +GK H V
Sbjct: 3275 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 3334
Query: 923 I 923
I
Sbjct: 3335 I 3335
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
T V+K Y VVAVN+ G T + E P+ L K V+ GE ++
Sbjct: 4087 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 4146
Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G
Sbjct: 4147 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 4203
Query: 813 IAETSAVITV 822
AE + ITV
Sbjct: 4204 EAEANIKITV 4213
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+
Sbjct: 1717 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 1762
Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
P FI + + ITVK T++ ++ P+P + W++ N+ + +T
Sbjct: 1763 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 1820
Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
D E I + S + D G+Y+ NS G A +T+
Sbjct: 1821 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 1863
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
G + EC + P P+ W FKG +E+V ++ + D VL I ++
Sbjct: 5618 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 5672
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
YT A N G S L+IKT P+V P K ++GE++ L P+
Sbjct: 5673 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 5728
Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
W K+ + ++ +D ++ I + +D G Y + ENS G + +
Sbjct: 5729 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 5787
Query: 821 TVEEPTEENAEPPLF 835
TV + EPP F
Sbjct: 5788 TVADV----PEPPRF 5798
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
+ N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L
Sbjct: 2911 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 2970
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
+ V G P PTITW PV++ + T K+ D G Y +KAEN G
Sbjct: 2971 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 3030
Query: 813 IAETSAVITV 822
+TV
Sbjct: 3031 TDTAEVKVTV 3040
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
K+E + + A NS G E S + E+ P IN ++ITV+ TI++ +
Sbjct: 4485 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 4544
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
NP P I + N I +E D E+VIT S+ D+G YK A+N GK
Sbjct: 4545 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 4602
Query: 916 S 916
+
Sbjct: 4603 T 4603
Score = 45.2 bits (102), Expect = 5e-04
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)
Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S
Sbjct: 2388 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 2442
Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
+ I +K+K+ +P IE R G P K N K +P
Sbjct: 2443 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 2502
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
GDTH T+ K D + +KA NSEG + ET I + P + P
Sbjct: 2503 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 2556
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
+ N+K+ +E + + A N+ G + S P + P++ E L V+ G ++
Sbjct: 2320 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 2379
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
+ G P P +TW N K + + + + + PK + K G YT+ A N G
Sbjct: 2380 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 2439
Query: 813 IAETSAVITVE-EPTE 827
+ I V+ +PT+
Sbjct: 2440 TDSVTINIKVKSKPTK 2455
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
N+K E + V+AVN G + S P +I P+++ + + ++ G + L
Sbjct: 3793 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 3852
Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
+G P PT TW + P D + + +I P K D G Y LK +N G
Sbjct: 3853 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 3912
Query: 815 ETSAVITVEE 824
E + V++
Sbjct: 3913 EAIFEVIVQD 3922
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G
Sbjct: 4475 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 4534
Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
E++ I GNP+P I N P+ + T D + I I K D G Y +
Sbjct: 4535 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 4594
Query: 807 AENSEG 812
A N G
Sbjct: 4595 ATNKYG 4600
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P
Sbjct: 3214 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 3273
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
P+I WF + + + + + DN L + D+G + VA N +G
Sbjct: 3274 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 3325
Score = 41.9 bits (94), Expect = 0.005
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ ++A+N G+ + S + N P + N QEI VK L V+ P P
Sbjct: 2922 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 2980
Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ITW + + S N DG+ V + S D+G Y A N G + +V
Sbjct: 2981 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 3038
Query: 922 TI 923
T+
Sbjct: 3039 TV 3040
Score = 41.5 bits (93), Expect = 0.006
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
KN + +AL D T ++ LK +E + + A N G + S N
Sbjct: 2301 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 2357
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
P + + TVK T+K + + P P +TW N + I S+ +N I
Sbjct: 2358 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 2415
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
SG Y A+N G S VTI+++
Sbjct: 2416 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 2448
Score = 41.1 bits (92), Expect = 0.008
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT
Sbjct: 2668 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 2726
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A NA G +T ++ +++ P S +G
Sbjct: 2727 IKAVNANGEDEATVKINVIDKPTSPNG 2753
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++ + + YP+ + W + I+ + F + DD ATL I ED G +
Sbjct: 5714 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 5772
Query: 584 VAKNAAGFASSTTELIV 600
V +N+ G S T + V
Sbjct: 5773 VVENSVGSDSGTVNVTV 5789
Score = 40.3 bits (90), Expect = 0.015
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP V+E +S R G SV+L Q + I W ++ V+ S SI L+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 794 PKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEE 828
K+ +E G+Y A+ G ++SA++ +E+ E
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDVE 473
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP F LR + + C ++G P P I W + + +D
Sbjct: 6383 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 6440
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V +L I +DAGT+T A N G S L V+
Sbjct: 6441 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 6478
Score = 39.9 bits (89), Expect = 0.019
Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P KP+ + C V PEP WL G E+ E+ E+ +
Sbjct: 5211 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 5268
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
Y +K V G YTV N G + L ++ PP + + + + I+ G+
Sbjct: 5269 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 5322
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
V L G + N + + PT + D H + + V++ G Y
Sbjct: 5323 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 5382
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G A T + V E + PL I+ T T+ VT ++
Sbjct: 5383 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 5437
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+S E +T + +++ ++T + E +++ A N G
Sbjct: 5438 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 5482
Score = 39.5 bits (88), Expect = 0.026
Identities = 29/153 (18%), Positives = 62/153 (40%), Gaps = 5/153 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+P + ++ E+ + I E ++ V P+ + P + + +TV E T L
Sbjct: 623 EPSTPRRRSSIDMRRESVQEILEKTSTPLV--PSGASGSAPKIVEVPENVTVVENETAIL 680
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIELVITNVDSEIDSGDYKCVASN 910
+V+ +P P+ W++ + + DG+ + L + S+ D G Y N
Sbjct: 681 TCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQ-DEGPYTLTIEN 739
Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
G S ++ + + + + K E++ G
Sbjct: 740 VHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 772
Score = 39.1 bits (87), Expect = 0.034
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T
Sbjct: 2083 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 2139
Query: 583 CVAKNAAGFASSTTELIV 600
A NA+G + E+IV
Sbjct: 2140 LTATNASGSDKHSVEVIV 2157
Score = 39.1 bits (87), Expect = 0.034
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N
Sbjct: 6408 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 6466
Query: 1652 GTSSVEVTLKVYDKPSKP 1669
G E L V K +P
Sbjct: 6467 GVDVSECVLTVQTKGGEP 6484
Score = 38.7 bits (86), Expect = 0.045
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
++ + E ++K P+ S AP VE + T C+V G P P WF
Sbjct: 637 RESVQEILEKTSTPLVPSGASGS-APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWF 695
Query: 545 RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + + F+ D ++ L + + +D G +T +N G S+ +L+V
Sbjct: 696 KGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV--- 752
Query: 604 LSDHG 608
SD+G
Sbjct: 753 TSDNG 757
Score = 38.3 bits (85), Expect = 0.059
Identities = 18/96 (18%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
PP ++ ++Q G E++ ++ W++DG+ ++ S+ + +G KL+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1165 IYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSI 1196
+ + +G Y C+ G + +A++ +E+ +
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDV 472
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
+ +K Q + V A+N+ GE+ S P + P++ + + V+ G+++
Sbjct: 3204 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 3263
Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
V G P P I W N P+ + T D +T + T L K D G Y + A N
Sbjct: 3264 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 3323
Query: 811 EGIAETSAVITV 822
G E + +
Sbjct: 3324 SGKDEHEVDVNI 3335
Score = 37.5 bits (83), Expect = 0.10
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
KS+ D H + KP K V+D E +Y +KA N G + + + A
Sbjct: 1416 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 1475
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P +++ +K TIK ++ P+P W N + + + + + +
Sbjct: 1476 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 1535
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I N DSG + NS+G A VT+
Sbjct: 1536 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 1566
Score = 37.1 bits (82), Expect = 0.14
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT--KEKTSVIRIKELKRSHSSKYTIEAS 1648
++T + G P P W+K ++ + + T KE T + + + + YT+
Sbjct: 679 ILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIE 738
Query: 1649 NTAGTSSVEVTLKV 1662
N GT S +V L V
Sbjct: 739 NVHGTDSADVKLLV 752
Score = 37.1 bits (82), Expect = 0.14
Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y
Sbjct: 6664 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 6722
Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+L + + V V + +K PP + + SS P G ST + +
Sbjct: 6723 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 6769
Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
E++ ++ T +W + ++++KT ++++ V + D + KV+K
Sbjct: 6770 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 6824
Query: 1476 ETK 1478
E K
Sbjct: 6825 EKK 6827
Score = 36.7 bits (81), Expect = 0.18
Identities = 20/91 (21%), Positives = 36/91 (39%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PP +++ R + G V L V +Q EW + +++ S + A L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ K+ +G+YK + + G V I
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKI 467
Score = 36.7 bits (81), Expect = 0.18
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 4/125 (3%)
Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
R+ + D + E +L+ ST + PKIV+ + L P
Sbjct: 629 RRSSIDMRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGSP 688
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCG--HADV 1371
P W S+ + K D K + +L + K + D G Y L +EN G ADV
Sbjct: 689 APTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADV 748
Query: 1372 EMNVT 1376
++ VT
Sbjct: 749 KLLVT 753
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+E + + A N G ++ S N +P + + + +T+K +I V+
Sbjct: 2620 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 2679
Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+
Sbjct: 2680 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 2737
Query: 917 HGARVTIDVEKVT 929
++ + ++K T
Sbjct: 2738 ATVKINV-IDKPT 2749
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
L+N + N +LTC G P P + W +DG + + R
Sbjct: 6395 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 6454
Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
Y A ND G + CV+ +Q K
Sbjct: 6455 AGTYTVTATNDLGVDVSECVLTVQTK 6480
Score = 36.3 bits (80), Expect = 0.24
Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 4/104 (3%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY--- 560
E +S P FV K R G+ + EC+V+ P W + + + +
Sbjct: 105 EAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDL 164
Query: 561 -DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
D + L IR DAG + C +N G ++ L E P
Sbjct: 165 GDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFEEP 208
Score = 36.3 bits (80), Expect = 0.24
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++
Sbjct: 1760 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 1819
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
+ + L I D G + KN+ G L +++ P +G
Sbjct: 1820 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 1872
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENI---ELVITNVDSEIDSG 902
G + + + +P P+I W + ++ PS + Q G ++ LVI ++ D G
Sbjct: 19 GDLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAG-DGG 77
Query: 903 DYKCVASNSAGKSS 916
YKC A N G+S+
Sbjct: 78 AYKCTARNQLGESN 91
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PP V W+K+ +L+ +Y + I +K +YT+ A N+ GT V L
Sbjct: 6294 PPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 6353
Query: 1661 KV--YDKPSKPE 1670
V + +P K E
Sbjct: 6354 NVTRHSEPLKFE 6365
Score = 35.5 bits (78), Expect = 0.42
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVK 845
H +T L PKK + V A + S IT + PT + ++I
Sbjct: 4772 HRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLT---RDILAY 4828
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDY 904
K++ +P P +T+ + ISP++ + + + +T SE+ D G Y
Sbjct: 4829 AGERAKILVPFAASPAPKVTFSKGENKISPTDPRVK-VEYSDFLATLTIEKSELTDGGLY 4887
Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
NS G S R+ + V+K +H++
Sbjct: 4888 FVELENSQGSDSASIRLKV-VDKPASPQHIR 4917
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++++ + G P P+ W +K +M + + I D+G FT
Sbjct: 1491 GETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMS-SERGKHIMKIENAVRADSGKFTI 1549
Query: 584 VAKNAAGFASST-TELIVEAPLSDHG 608
KN++G ST T +V P G
Sbjct: 1550 TLKNSSGSCDSTATVTVVGRPTPPKG 1575
Score = 34.7 bits (76), Expect = 0.73
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 499 EKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDF 556
++ ++ +++AP I E L G+T++F ++G P P +TW F I +
Sbjct: 2349 DRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQI 2408
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
+ ++ ++ + + + +G +T A N G S T + V++
Sbjct: 2409 E---NEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKS 2451
Score = 33.5 bits (73), Expect = 1.7
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G V G P P ITW F T + S D ++D ++ D GT+
Sbjct: 2965 GQDFSLNIPVSGEPTPTITWTFEGTPV--ESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3022
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A+N G ++ ++ +++ P S G
Sbjct: 3023 IKAENENGTDTAEVKVTVLDHPSSPRG 3049
Score = 33.1 bits (72), Expect = 2.2
Identities = 53/305 (17%), Positives = 115/305 (37%), Gaps = 21/305 (6%)
Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVE 1282
+ WY+ +++ ++ +++ + L + K TE+ +C C + +S+ +K+E
Sbjct: 409 IEWYRDGTLVRNSSEYSQSFNGSIAKLQVNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIE 468
Query: 1283 VVEFPPKIV----DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ +++ D E EY+ + TL QA + SK K S
Sbjct: 469 QSDVEEELMKHRKDAEDEYQKEEQKSQTL----QAETKKRVARRSKSKSKSPAPQAKKST 524
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPSPPGKPNILEIDSSSI 1397
S+S +VE+ + + + ++ + +TI ++ + E D
Sbjct: 525 TSESGRQEASEVEHKRSSSVRPDPDEESQLDEIPSSGLTIPEERRRELLGQVGESDDEVS 584
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
+ P G + D + +S+ ++ ++S T R + +
Sbjct: 585 ESISELPSFAGGKP------RRKTDDKPKKVSIAPVSTNKSSDDEPSTPR--RRSSIDMR 636
Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
+ + E T V +P + + +N+T NE LTC G P P W++
Sbjct: 637 RESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFK 696
Query: 1518 DGKKL 1522
+++
Sbjct: 697 GSREV 701
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/97 (21%), Positives = 34/97 (35%), Gaps = 2/97 (2%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P + P+ V E +L C++ P P W E++ + H
Sbjct: 658 GSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHT 717
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
L + + EG YT+ N G S + L +
Sbjct: 718 V--ALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 752
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+PP + + V G D L + P P I W F+G + D+ + + E
Sbjct: 2948 VPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTK 3007
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
+ + + GTY + A N G + + + + P
Sbjct: 3008 F----HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSP 3047
Score = 31.5 bits (68), Expect = 6.8
Identities = 34/179 (18%), Positives = 68/179 (37%), Gaps = 15/179 (8%)
Query: 752 VILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGDTHSIT-ILKPKKVKDEGVY 803
+++ + +P+PTI W + + V+ L T G + T ++K D G Y
Sbjct: 21 LLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTL-TPLGGSLYKATLVIKEPNAGDGGAY 79
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPV 861
A N G + + + + A+ P F+ + + I I + +V
Sbjct: 80 KCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSAST 139
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVD----SEIDSGDYKCVASNSAGKSS 916
P W ++ +S F + + ++ S D+G Y+C N G+++
Sbjct: 140 PVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETN 198
>Z73897-6|CAM35838.1| 6629|Caenorhabditis elegans Hypothetical protein
ZK617.1c protein.
Length = 6629
Score = 318 bits (782), Expect = 2e-86
Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)
Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
+K+ + + K +C S +WY ++KEI SG +I+ E
Sbjct: 606 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 665
Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
D G C T L V E + F+ L + E+ A+L ++N+ A +VW
Sbjct: 666 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 725
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
R + I+ ++ EK R L I+ D+ E++ I +D +V V E
Sbjct: 726 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 785
Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
+ +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I
Sbjct: 786 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 845
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
++D GEY C + + A L V+ + F + L + ++ + D L + D
Sbjct: 846 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 903
Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
W++ I KF S TL I K ++ Y + + + V
Sbjct: 904 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 963
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
E P + ++ K G + V +Q P + + N K I + K + I
Sbjct: 964 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 1023
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
A + K + D G + L L N+ G A + + DKP PP P + + +
Sbjct: 1024 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 1083
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N
Sbjct: 1084 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 1143
Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
E +SD E+ Y K + + V+K + EP E+ I G +
Sbjct: 1144 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 1203
Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
+ + W++ G+ T K E++ C DHG+
Sbjct: 1204 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 1256
Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
+ +K + IK + KVG+ I G P PE +W NG L+ +
Sbjct: 1257 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 1315
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
+++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ +
Sbjct: 1316 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 1375
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR
Sbjct: 1376 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 1435
Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
V A N G SE L ++ IK D P D + + I W P K+GG+PI
Sbjct: 1436 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 1494
Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
+Y VE++ + K+WK A I L YQFR+ A N+ G P +K
Sbjct: 1495 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 1554
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
P + + S + T++W GG PI E K KG +
Sbjct: 1555 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 1608
Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
+T+ +EH CI + D +R++ +N+ G + +V L++ PS P P
Sbjct: 1609 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 1663
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L
Sbjct: 1664 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 1721
Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+ TY R+ A N+ G S+ L +D+ K
Sbjct: 1722 KGQTYQFRVKAVNKEGASDALSTDKDTK 1749
Score = 253 bits (619), Expect = 1e-66
Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)
Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
P ++D +E ++K G D +L + P P W ++ K + +
Sbjct: 2739 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 2798
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
+K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP
Sbjct: 2799 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 2858
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD
Sbjct: 2859 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 2918
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
E E + K+ ++ P + + D++ T GG P V
Sbjct: 2919 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2977
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
A ++ A N GE + S + + + + N
Sbjct: 2978 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3037
Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K
Sbjct: 3038 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3097
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG
Sbjct: 3098 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 3157
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L
Sbjct: 3158 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 3214
Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
S+ IV K D P D + V + W P +GG+PI Y VE K + W
Sbjct: 3215 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 3273
Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
A L+ TYQFR+ A N+ G P + P
Sbjct: 3274 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 3333
Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ +K +P+ + T+ + + S H ++
Sbjct: 3334 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 3393
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
D +++I EN G + +V VP P PL+I + +W P
Sbjct: 3394 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 3447
Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
+GG +L Y + D ++ W EVG T K N L Y R+ A N G S+
Sbjct: 3448 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 3505
Query: 2052 PLESDEP 2058
PLE++EP
Sbjct: 3506 PLEAEEP 3512
Score = 251 bits (614), Expect = 5e-66
Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
PKI+ R+ +IK G L VD+ P P W V S + S+
Sbjct: 3621 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 3680
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
+ D+G YKL+++N G + V + D+PS P P + ++ S + W P++
Sbjct: 3681 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 3740
Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+
Sbjct: 3741 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 3800
Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
T E V+ + +P KP + I N+ I++ GG P R D
Sbjct: 3801 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 3856
Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
K + K Y+ +A N G + S + + P
Sbjct: 3857 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 3916
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
+ + + + K G+ ++T P P++ W K G K E TT +T ++
Sbjct: 3917 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 3972
Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
I +RS S I+A N G + + + V DKP PE + +SR + T+ W P
Sbjct: 3973 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 4031
Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+
Sbjct: 4032 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 4090
Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
+ P+VIK D P D V + W P +GGSPI+ Y VE K+
Sbjct: 4091 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 4149
Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
G W + L N TYQFR+ A N G P + +T + P
Sbjct: 4150 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 4209
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
P V + T S L W P +GG+PI YI+E K + WT+ +
Sbjct: 4210 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 4269
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
+N+ EK+E FR+ A N+ G P++ S V +E+ P
Sbjct: 4270 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 4309
Score = 250 bits (612), Expect = 8e-66
Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y
Sbjct: 1870 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 1928
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
L N G + V +L KPS P G + + ++ W PE+ G + I +Y +
Sbjct: 1929 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 1988
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ +
Sbjct: 1989 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 2046
Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
+ P V+KP + + D+ GG P + K + + A ++
Sbjct: 2047 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 2106
Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
++ A N G + S VV + I ED+ KVG
Sbjct: 2107 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 2166
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
I+G P P+V W NG + K I + S + + R S KYTI A+
Sbjct: 2167 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 2225
Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK
Sbjct: 2226 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 2285
Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
+ W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D
Sbjct: 2286 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 2342
Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
P D++ V + W P +GG+PI +Y++E + + +W+ A
Sbjct: 2343 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 2401
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
+ L+ N Y+FR+ A N+ G S P + + P R+ + + + ++
Sbjct: 2402 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 2461
Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
+ P S +P +T + + + ++ K+ + ++ ++ D F I A
Sbjct: 2462 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 2520
Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I
Sbjct: 2521 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 2575
Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
D W+ KV + + L H Y R+ A N G S+PLE+
Sbjct: 2576 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 2627
Score = 243 bits (595), Expect = 1e-63
Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
R+K G + V+ + P P EW +N + +T ++ + LT K D+G
Sbjct: 3045 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 3104
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y
Sbjct: 3105 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 3164
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
VVE QE D W+ + T + L Y+FR AVN S + T + ++
Sbjct: 3165 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 3221
Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
+ P + + + + D+E GG P + +D G ++ A+
Sbjct: 3222 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 3281
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
+ ++ A N G + S G + KP ++ +
Sbjct: 3282 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 3340
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
K G + EG P P W N ++ ++T +S I I R + Y
Sbjct: 3341 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 3400
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E
Sbjct: 3401 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 3460
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K
Sbjct: 3461 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 3518
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
DVP D + + I W P+ NGG+P+ Y VE K++G W
Sbjct: 3519 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 3577
Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
L Y+FR+ A N G S P +D +IT + L P + R + +
Sbjct: 3578 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 3637
Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
++ + + P + + + + +V S + K D ++
Sbjct: 3638 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 3692
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
+ +N +G E +++ PS P PLE+ V + + +W P+ DGGA +
Sbjct: 3693 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 3747
Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP
Sbjct: 3748 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 3805
Score = 242 bits (593), Expect = 2e-63
Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+K G+ + +V P P+ W N K I + K + + + + K +G Y
Sbjct: 2162 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 2220
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+ N G V +N+ + KP+ P P + ++ + W PE+ G I +Y +
Sbjct: 2221 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 2280
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E W+ T ++ +L Y+FR AVN SD ET ++ +
Sbjct: 2281 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 2338
Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
P ++P + T+ + D ++L GG P + + K + + A
Sbjct: 2339 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 2396
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
+ ++ +A N G + S V+ + I + +K K
Sbjct: 2397 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 2456
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + G P P V W+ N+ + N + E S + +K+++R S +T
Sbjct: 2457 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 2516
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE
Sbjct: 2517 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 2576
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K
Sbjct: 2577 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 2636
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
D P D + V + W P +GG+PI +Y VE+K E W
Sbjct: 2637 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 2695
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A + L + Y+FRI A+N+ G P S + + + PP RN +
Sbjct: 2696 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 2754
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
P S +P + E V+ K+ G H ++ D + I
Sbjct: 2755 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 2813
Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
AEN G T V + H PS P PL++ + + +W PE DGGA +
Sbjct: 2814 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 2868
Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E
Sbjct: 2869 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 2923
Score = 235 bits (575), Expect = 3e-61
Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)
Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
+ RIK G+ + L + ++ P P +W N I + S+++ I D
Sbjct: 3337 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 3396
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++
Sbjct: 3397 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 3456
Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
Y+VE + W V + L Y FR AVN S E E
Sbjct: 3457 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 3516
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
+ + P V+KP + DI+ T GG P VT Y KK K + E
Sbjct: 3517 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 3572
Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
++ IA N G + S Q KP I ++ IK
Sbjct: 3573 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 3632
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
K V + G P P W + E + K T+ I KR+ S
Sbjct: 3633 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 3690
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y
Sbjct: 3691 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 3750
Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
+EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K
Sbjct: 3751 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 3809
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
P DN+ + I W P NGGSP+ Y +E K + G+ K
Sbjct: 3810 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 3868
Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
A R+QK TY++R+ A N+ G P S T P +
Sbjct: 3869 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 3925
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
F V +T+ +T SP + I + GK + T S + I +
Sbjct: 3926 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 3976
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
+ D +I A N G + ++++ TV P AP I V + +W
Sbjct: 3977 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 4028
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G
Sbjct: 4029 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 4087
Query: 2049 LSE 2051
LS+
Sbjct: 4088 LSD 4090
Score = 234 bits (572), Expect = 6e-61
Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + +K G+ V V P P +W N ++ + T + ++ L I
Sbjct: 1567 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 1626
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
+D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G
Sbjct: 1627 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 1686
Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T
Sbjct: 1687 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 1745
Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
K+TK ++P ++P K T + + D + + P+ +T Y KK K
Sbjct: 1746 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 1799
Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
+ E ++ ++ A N G E S VV +
Sbjct: 1800 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 1859
Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++
Sbjct: 1860 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 1918
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD
Sbjct: 1919 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 1978
Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
GG + Y IEK + RW+ + T + L EY FRV A N G S+ L
Sbjct: 1979 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 2036
Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
+ I+ K +VP D + V + W + +GG+PI + +E K + +
Sbjct: 2037 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 2094
Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
W+ A + L YQFRI ARN+ GT P D++ P R
Sbjct: 2095 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 2154
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+ + TLK+ +P + K + G+S +I + +
Sbjct: 2155 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 2212
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
K + I+A N G T+S ++ + K + P+ P P+E+ V + W P
Sbjct: 2213 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 2267
Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S
Sbjct: 2268 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 2325
Query: 2051 EPLESD 2056
+PLE++
Sbjct: 2326 DPLETE 2331
Score = 223 bits (545), Expect = 1e-57
Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + IK G ++ V P P W +++ I+ K + L +K++
Sbjct: 2448 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 2507
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G
Sbjct: 2508 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 2567
Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
I YV+E + + W+ + KT + L Y+FR V V+ S+
Sbjct: 2568 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 2624
Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
E + T + +KP K IT + ++L GG P + V +D
Sbjct: 2625 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 2680
Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
+ ++ A N G S V + P
Sbjct: 2681 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 2740
Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
+ N + K K G ++ + + G P P + W G +E+D + ++ + +
Sbjct: 2741 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 2800
Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D
Sbjct: 2801 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 2860
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+
Sbjct: 2861 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 2918
Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
LE+ E I+ K D + D + + W P +GG+PI Y VE++
Sbjct: 2919 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2977
Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
W A + L TYQFR+ A N+ G S P + P
Sbjct: 2978 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3037
Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
R+ V++ TL + +P + + + T I + + ++
Sbjct: 3038 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3097
Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
D ++I A N G + V + +P P PL + + V+ W
Sbjct: 3098 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 3152
Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G
Sbjct: 3153 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 3209
Query: 2050 SEPLESD 2056
S PL SD
Sbjct: 3210 SAPLTSD 3216
Score = 209 bits (510), Expect = 2e-53
Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)
Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
++ ++ G + + + Y P+P + + I + + T ++ +T + +
Sbjct: 4317 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 4376
Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I
Sbjct: 4377 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 4436
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET +
Sbjct: 4437 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 4493
Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
++ + +P +P T+E ++ T GG P Q V R+ + KA
Sbjct: 4494 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 4553
Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
+ N Y + A+N G+ E S + P N + +
Sbjct: 4554 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 4613
Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
+ G+ + P P+V + K NK+ D + + + + I++ + +
Sbjct: 4614 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 4673
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T
Sbjct: 4674 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 4732
Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++
Sbjct: 4733 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 4791
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
+V K +VP+ D+ + W P ++GGS II Y+V+ + +W
Sbjct: 4792 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 4849
Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
AR+ L N ++FRI A+N G S P ++ + PP P +
Sbjct: 4850 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 4909
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
T+ W P +GGS IT Y +E + WT E ++ ++E
Sbjct: 4910 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 4969
Query: 1934 DEIIFRISAENTVGVSLPT 1952
++ FR+ A N G +P+
Sbjct: 4970 NDYEFRVVAINAAGKGIPS 4988
Score = 199 bits (485), Expect = 2e-50
Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
+D + +L + + N ++++ NN G ++ + I D +P PG+P I +
Sbjct: 1414 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 1473
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F
Sbjct: 1474 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 1533
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
R AVN+ SE +E ++ K I + LK+IT + + GG P P
Sbjct: 1534 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 1592
Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
+V W++ ++L+ + T + R Y+ N HG E +
Sbjct: 1593 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 1652
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
+ +P + N ++ D ++ E I Y KL+ + K
Sbjct: 1653 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 1710
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
K + I LK+ + ++ ++A N G S T K YD+P K P ++ +
Sbjct: 1711 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 1769
Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
+ V++EW+PP DGG +T+Y IEK W + V D I L E EY F
Sbjct: 1770 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 1829
Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
RV A N G EA + S +V K P ID E++ + K G
Sbjct: 1830 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 1876
Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
D V + KK W RI+ T + R R G T+ +
Sbjct: 1877 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1936
Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
DK ++ L PS P VS L+W PE +GG+PI +Y IE +
Sbjct: 1937 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 1996
Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
W V G S + + N++ E FR+ A N G S P + + L K+ VP
Sbjct: 1997 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 2053
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
P E+ + V +W P+ DGGAP+ + I +D W E V + +
Sbjct: 2054 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 2110
Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+L E Y RI ARN+ G +P + +
Sbjct: 2111 PNLKEGEEYQFRISARNKAGTGDPSDPSD 2139
Score = 191 bits (465), Expect = 5e-48
Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)
Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
W + ++D +K + S+ K ++R T YT +A + K VEV+
Sbjct: 1892 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 1950
Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
P ++ Y + +D+ V P D + + + + P S++
Sbjct: 1951 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 2007
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
T+ ++ +++R N G +D + N IL K P KP +++ D +
Sbjct: 2008 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 2067
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A
Sbjct: 2068 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 2125
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT
Sbjct: 2126 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 2183
Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
W +GK + +KA EN Y A N +G + + ++ KP
Sbjct: 2184 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 2243
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
K +V D + A ++ PP + + +Y+ D + +
Sbjct: 2244 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 2297
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
+ + L + K+ ++A N+ G S ++ K +D+P +P P +
Sbjct: 2298 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 2356
Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
+ V ++W PPL DGG + +Y IEK RW V T + L N EY FR
Sbjct: 2357 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 2415
Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
V+A N G S+ ++ VI ++ I++ +P +
Sbjct: 2416 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 2475
Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
+ +E G + K ++++ + F I A N G + KI
Sbjct: 2476 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 2532
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
+ T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W
Sbjct: 2533 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 2589
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
V G ++ + E FR++A N G S P E+ L K P AP EI
Sbjct: 2590 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 2648
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ V W P DGGAP+ Y + ++D W +V V + +L E
Sbjct: 2649 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 2708
Query: 2036 TYMIRIYARNEIGLSEPLES 2055
Y RI A+N+ GL +P +S
Sbjct: 2709 KYEFRIRAKNKAGLGDPSDS 2728
Score = 190 bits (463), Expect = 9e-48
Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI
Sbjct: 4057 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 4115
Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N
Sbjct: 4116 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 4175
Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+Y+FR AVN + S +E V K +P V K KN + E + L
Sbjct: 4176 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 4234
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
GG P + + KKL T N ++ IA N GE
Sbjct: 4235 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 4290
Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
E S +V I++ +P+ I+N +DI + G+ + G P +I NGN
Sbjct: 4291 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 4348
Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
EN++ + VI KRS + Y I A+N G + ++ + V D P KP
Sbjct: 4349 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 4407
Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++
Sbjct: 4408 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 4464
Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
L+ N Y FRV A+N G E LE+ + IV K D P E++ + W
Sbjct: 4465 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 4523
Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
+GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N
Sbjct: 4524 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 4583
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
G + IT T P + + + K P + +P +
Sbjct: 4584 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 4643
Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ V + IE + D ++ + EN+ G ++S S+RL+
Sbjct: 4644 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 4695
Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
V P +P IR+ + + W P DGG+P+ Y + D+ + W +V
Sbjct: 4696 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 4754
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
V L + + L +++ Y R+ A + G+SEP E
Sbjct: 4755 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 4788
Score = 183 bits (445), Expect = 1e-45
Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I
Sbjct: 3772 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 3831
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
+I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A
Sbjct: 3832 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 3891
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
VN+ S+++ + ++P + L K + E + +T F PQP +
Sbjct: 3892 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 3949
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
+W ++G K T +++ K A N +GE E + + + KP
Sbjct: 3950 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 4009
Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
+ +H W G E+ YK + + ++ + +
Sbjct: 4010 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 4066
Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
++ L+ ++ I A N G S V V +K +D P P P I + + V++
Sbjct: 4067 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 4125
Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A
Sbjct: 4126 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 4184
Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
N G E SEP+ + ++ P N S +TW ++GG+PI Y
Sbjct: 4185 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 4243
Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
VE K+ G W ++ L Y+FR+ A N G P D + I
Sbjct: 4244 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 4303
Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
+ P N + + T++ P + G PI + + T +V V
Sbjct: 4304 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 4362
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
K D ++ISA N G + V P PT P+ +
Sbjct: 4363 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 4417
Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y
Sbjct: 4418 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 4474
Query: 2040 RIYARNEIGLSEPLESDE 2057
R+ A N+ G+ EPLE+D+
Sbjct: 4475 RVRAENQYGVGEPLETDD 4492
Score = 178 bits (434), Expect = 3e-44
Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D P P KP + + D I+I W+ N G + + Y+VE +E + W T
Sbjct: 3520 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 3579
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S NLK Y FR AVN SD S+ T+ I + + P + + I +
Sbjct: 3580 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 3637
Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
L F G P P TW D + + + YK N
Sbjct: 3638 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 3697
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ GE E V +Q +P + +V D + V+ PP + + N +
Sbjct: 3698 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 3751
Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
++ T S I + +L H ++ + A NT G S S+ V K
Sbjct: 3752 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 3811
Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV
Sbjct: 3812 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 3870
Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
+ ++ + Y +RV+A N G + +S K + P
Sbjct: 3871 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 3930
Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
E + IT P SP D + +EG K + I + +
Sbjct: 3931 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 3984
Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
+I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I
Sbjct: 3985 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 4038
Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S +
Sbjct: 4039 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 4096
Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
V ++ P P+ P EI +N V +W P DGG+P+LGY + W
Sbjct: 4097 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 4155
Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
V V + + L EN TY R+ A N G EP EP P
Sbjct: 4156 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 4203
Score = 176 bits (428), Expect = 2e-43
Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+I+ + ++ +A F E + + RW ++G E+ S+ + K I
Sbjct: 5004 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 5063
Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
+ DAGEY+ EV G+ TA L V+ P + +P IL + Y +
Sbjct: 5064 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 5122
Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
P V ++ + T + D T+ E + EYT ++TT
Sbjct: 5123 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 5182
Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ V P + I T + ++ P + + S +++K +K
Sbjct: 5183 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 5236
Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
+ + + +K + G+ Y+ R+ EN G V + I P PP P
Sbjct: 5237 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 5296
Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
I+++ + + W P + G + Y+VE QE + EW + + NL
Sbjct: 5297 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 5356
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
YR+R +AVN+ +SD +E + + + P + PL ++ E + C
Sbjct: 5357 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 5415
Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
G P+P+ W++ K+L T+K T N+ Y C A N G
Sbjct: 5416 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 5475
Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
T + I+ KP + I + + + G+ + + P E W K+G K+EN+ +
Sbjct: 5476 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 5535
Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I
Sbjct: 5536 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 5594
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y
Sbjct: 5595 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 5651
Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
FR+IA+N G S+ E + P++I
Sbjct: 5652 EFRIIAENKHGQSKPCEPTAPVLI 5675
Score = 171 bits (416), Expect = 5e-42
Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)
Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+++R N GH + VT ++KP P P + +I +S + W+ P G +
Sbjct: 4179 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 4238
Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++
Sbjct: 4239 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 4298
Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
V+ E + P + LK+IT E I++ + GG P+P + + + +
Sbjct: 4299 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 4356
Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
T YK A N +G+ V+ KP I DI
Sbjct: 4357 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 4416
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
Q + W G + I K ++ + +R++ L +
Sbjct: 4417 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 4471
Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
++ + A N G T V +D P P P + E S E++T++W P DG
Sbjct: 4472 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 4530
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
G + Y IEK E + W K A + + + L Y FRV A N G E ++
Sbjct: 4531 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 4590
Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
S PI A P + +P + + +I
Sbjct: 4591 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 4650
Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
+ K I+K + + + N G SD K + P+ P+
Sbjct: 4651 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 4704
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
+ V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + +
Sbjct: 4705 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 4763
Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
+ + + FR+ AE GVS P E V + K+ VP+ P AP +R S W
Sbjct: 4764 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 4822
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N
Sbjct: 4823 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 4880
Query: 2047 IGLSEPLESDE 2057
G S+P E
Sbjct: 4881 AGFSKPSPPSE 4891
Score = 163 bits (396), Expect = 1e-39
Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++
Sbjct: 1118 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 1175
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
+D + W+ PE G + I Y++E +E +W V + + K + Y
Sbjct: 1176 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 1235
Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
+R AVN+ D + + K+ K K +K++ + E I+ G P
Sbjct: 1236 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 1294
Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
P+ W +GK LK ++ + + N G +++ V
Sbjct: 1295 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 1354
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
+ +P DI G + P + ++N +Y K
Sbjct: 1355 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 1414
Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I +
Sbjct: 1415 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 1473
Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
+ + I W+PP DGG + +Y +E +PD W +V V D I L E EY
Sbjct: 1474 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 1531
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
FRV A N G + E + +P+ + W K GG
Sbjct: 1532 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 1589
Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
PI + K +++ + I + ++R+ +N G
Sbjct: 1590 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 1645
Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+
Sbjct: 1646 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 1703
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
W V + H I+ +K+ FR+ A N G S + K+ T
Sbjct: 1704 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 1760
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
++ ++ V W P+ DGGAP+ Y I + W E GKV + I
Sbjct: 1761 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 1820
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
L E Y R+ A N+ G E SD KV+
Sbjct: 1821 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 1850
Score = 142 bits (343), Expect = 3e-33
Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
P PP I + I W P G S I Y VE +E +T W S N+ + +
Sbjct: 4902 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 4961
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
++ L+ + Y FR A+N S + K+ + + V KP T +P N
Sbjct: 4962 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 5019
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
TC G P+P W R+G++L ++++ +E Y
Sbjct: 5020 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 5079
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
N +G + + +Q PVI +D+ GD + G P N +
Sbjct: 5080 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 5136
Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
++ D I + +I I L + +Y SN +G ++ L V P P+G
Sbjct: 5137 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 5196
Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L
Sbjct: 5197 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 5255
Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
EN EY FRV AQN G L SE PI+ + D P + + V ++W
Sbjct: 5256 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 5314
Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
+GG + Y VE ++E +W + L Y++R++A N+ G
Sbjct: 5315 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 5374
Query: 1848 S 1848
S
Sbjct: 5375 S 5375
Score = 132 bits (320), Expect = 2e-30
Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)
Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
K T KL V V++ P K R I+ + + + ++ P+ N + + +++K
Sbjct: 4391 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 4446
Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
+ T +V N DA +++R EN G + +E + I+ D P P
Sbjct: 4447 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 4506
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ +
Sbjct: 4507 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 4566
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
L +Y FR A N + S + + + P + + ++I E +
Sbjct: 4567 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 4624
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
+ F P PKVT+ + K+ K Y + Y N
Sbjct: 4625 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 4684
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
G S + + KP S + I+ + D W+ + G P I K
Sbjct: 4685 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 4741
Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
+ + K +++ + + L + + ++ + A G S V V ++
Sbjct: 4742 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 4801
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D +
Sbjct: 4802 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 4858
Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
+ + L +N E+ FR+IA+N GFS+ + SE +K+ P I
Sbjct: 4859 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 4917
Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
ITW ++GGS I Y VEI++ G W + KL Y+FR+
Sbjct: 4918 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 4977
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A N G +P I I + + S+P+ V E T++
Sbjct: 4978 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 5015
Score = 129 bits (311), Expect = 2e-29
Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ +
Sbjct: 4787 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 4845
Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
WI+ K Q + L+ N + FR A N S S +E ++ P
Sbjct: 4846 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 4905
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
+ K+I + + G K+T Y R+ G L T + Y R
Sbjct: 4906 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 4963
Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
++ +A N G+ S G IQ+ +P I + ED Q + +
Sbjct: 4964 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 5023
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
AV G P P W +NG +L Y + IKE+ + +YT+E SN
Sbjct: 5024 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 5081
Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
G+ + L V P PVI +++ TI L G L K P
Sbjct: 5082 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 5127
Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
+ + ++D D T I + +++ ++ G E S T L+V
Sbjct: 5128 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 5187
Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
P I + ++W P +GGS I Y VE + K +W
Sbjct: 5188 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 5247
Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
I L N Y+FR+ A+NE G P S+ I PP+ P N + +
Sbjct: 5248 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 5307
Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
VTL W P S+GG + YI+E + + W + + + + N+ + + +R+
Sbjct: 5308 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 5367
Query: 1942 AENTVGVS 1949
A N G+S
Sbjct: 5368 AVNDAGLS 5375
Score = 124 bits (299), Expect = 7e-28
Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)
Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
W P +GGSPI +Y K++++ KW K + L + Y+FR+ A
Sbjct: 4720 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 4779
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
+ G S P D + P+QP V + S L+W +P +GGS I Y ++
Sbjct: 4780 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 4838
Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
++ W + + E C + +++ E FRI A+N G S P+ S+ +L
Sbjct: 4839 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 4895
Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
+ P PP + + +G N +W P DGG+ + GYN+ IR+ T+W
Sbjct: 4896 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 4954
Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
+V +F + L E + Y R+ A N G P P K+ GS
Sbjct: 4955 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5002
Score = 99 bits (238), Expect = 2e-20
Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)
Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P I WY++ + I + +N+ +I N D+G Y C A+ G +H
Sbjct: 626 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 682
Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
++ K +F+ L + E K +L C+ + WY K I D R II+
Sbjct: 683 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 742
Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
+ GR I +D + + V+E F+ ++ +V E D+A
Sbjct: 743 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 802
Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+
Sbjct: 803 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 862
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
A++ +V+ + I L++ +V + + T + WF++G +I
Sbjct: 863 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 921
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+ LKI ++++A Y + + + +TV E
Sbjct: 922 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 962
Score = 99.1 bits (236), Expect = 3e-20
Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)
Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ +
Sbjct: 1066 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 1123
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
++++KE E FR+ A N G+S P +SV + VP P ++ V +
Sbjct: 1124 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 1182
Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
+W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A
Sbjct: 1183 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 1242
Query: 2045 NEIGLSEPLESDEPFKV 2061
N+ G +P + +P K+
Sbjct: 1243 NKAGPGDPCDHGKPIKM 1259
Score = 98.3 bits (234), Expect = 5e-20
Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
+S + TL W P ++GGS IT+Y++E + + W VTV +V + + + +
Sbjct: 5200 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 5256
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW
Sbjct: 5257 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 5313
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P DGG L GY + ++ W + +N+ +L + Y R++A N+ G
Sbjct: 5314 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 5373
Query: 2049 LSEPLESDEPFKVIPGEG 2066
LS+ E D+ G G
Sbjct: 5374 LSDLAELDQTLFQASGSG 5391
Score = 94.3 bits (224), Expect = 9e-19
Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)
Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
L D+ +T+ K + L +H ++ + A N G S + ++ +D P
Sbjct: 5233 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 5292
Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
+ P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y
Sbjct: 5293 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 5351
Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
+ L + +Y +RV A N G S+ E + + + A ++ E
Sbjct: 5352 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 5410
Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
F E + GSP +Y+ + + K+ I L+ + ++ A
Sbjct: 5411 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 5469
Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
N GT + T + PP + + T++ P +
Sbjct: 5470 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 5525
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + ++ S I T I N +D +R+ EN+VG T + +V
Sbjct: 5526 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 5579
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K
Sbjct: 5580 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 5638
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
I L Y RI A N+ G S+P E P +IPG+
Sbjct: 5639 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 5678
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
T LDVP I E + W P NGG+ ++ Y VE + W+
Sbjct: 3417 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 3476
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A++ KL Y FR+ A N G S P +++ I P V++
Sbjct: 3477 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 3536
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
+ +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+
Sbjct: 3537 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 3594
Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
A N G S P++ ++ K + P TA +I++ N+ + G P+
Sbjct: 3595 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 3649
Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
P + + + V K ++ F +++ Y +++ +NE+G E
Sbjct: 3650 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 3702
Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
+ F+VI + A E P E ++V
Sbjct: 3703 EAIFEVIVQDRPSAPEGPLEVSDV 3726
Score = 88.6 bits (210), Expect = 4e-17
Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ +
Sbjct: 6053 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 6111
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
+TI + K D+G YT++A+NS G E + V +E PL E K
Sbjct: 6112 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 6164
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
++ R P T++ N +I + +T + G + D D
Sbjct: 6165 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 6224
Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
V+ S S +D + T+ + + V+ TV TK
Sbjct: 6225 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 6276
Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
+S R + + G +I+ + D + + L K T +P F
Sbjct: 6277 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 6336
Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
+L D E + A ++ + ++ W +GE I +++ L I +
Sbjct: 6337 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 6396
Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
DEG+Y C + E A +TV VE + L + VN
Sbjct: 6397 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 6456
Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV
Sbjct: 6457 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 6516
Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
+ +++ V E + RLP + P T+E + E L V W++
Sbjct: 6517 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 6576
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
IE E+ + L I+ +DD Y ++ K
Sbjct: 6577 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 6616
Score = 87.8 bits (208), Expect = 7e-17
Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S
Sbjct: 5417 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 5476
Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
L++ KP P +++ TIE K P ++ + + +NN
Sbjct: 5477 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5536
Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
+ D+ T I + +RV+ +N VG V T DVP
Sbjct: 5537 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 5590
Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
+D E+V ++W P +GGS + +Y +E ++ G W I+ L
Sbjct: 5591 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 5649
Query: 1834 TYQFRIYARNEIGTSLP 1850
Y+FRI A N+ G S P
Sbjct: 5650 QYEFRIIAENKHGQSKP 5666
Score = 70.5 bits (165), Expect = 1e-11
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
+P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V +
Sbjct: 5190 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 5248
Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
+ + L ENH Y R+ A+NE G+ PL S+ P
Sbjct: 5249 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 5282
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP
Sbjct: 5364 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5423
Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
W CK + GD + I+ D YT +A NS G T A +
Sbjct: 5424 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 5482
Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
++ +P +FI ++ +KG TI+L P W ++ E I +
Sbjct: 5483 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5536
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ D + L I+N E D G+Y+ V NS G S VT+
Sbjct: 5537 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 5579
Score = 66.9 bits (156), Expect = 1e-10
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ K +G + F C+V P +TW + +K S + Y+ ++ L
Sbjct: 6056 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 6114
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I V +D G +T AKN+ G T E IV ++ H + +
Sbjct: 6115 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 6170
Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
E P F+ + + + + L C L P P I W+ G V ++ + V+
Sbjct: 6171 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 6229
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
S + CS L+I N + GTYTV A N G VL ++T EP P+V
Sbjct: 6230 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 6278
Score = 66.5 bits (155), Expect = 2e-10
Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P+F+ + + G + PEP I WL GE I ++ + +
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 6390
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
L+I++ KK EG Y A N G+ L +K + + +V + L
Sbjct: 6391 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 6450
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
IV GESV A+V G P + W +N + + DG+T S TI D
Sbjct: 6451 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 6508
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
G Y L+ S+G S V E A+PP + R ++ G+
Sbjct: 6509 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 6563
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
++ W+R +E I +E + G +L I NV+ + D G Y
Sbjct: 6564 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 6608
Score = 62.9 bits (146), Expect = 2e-09
Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
E P L G S SA V G P P I W N + + ++ T
Sbjct: 6332 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 6391
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
+ + K DEG Y +A NS G +T A +TV ++P + E L + +
Sbjct: 6392 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 6451
Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
+ G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+
Sbjct: 6452 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 6509
Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
G Y+ V S S + V + + V L S G + +E + ++
Sbjct: 6510 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 6569
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
+W+ ++I + + ++ G D G+ + +VK+++
Sbjct: 6570 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 6617
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
P F +L T G + +F V G P P I W I S F+ Y ATL
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 6392
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
I + D G + C A N+AG + L V + PL + + V
Sbjct: 6393 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 6443
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
+K + V+ G + E R+ PE ++ W+ G+E+ + S++ +
Sbjct: 6444 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 6494
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ + I + G Y + V +G + + + GEK P V S+
Sbjct: 6495 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 6549
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
G S + + T+ W + ++ + + + + G+T + I K + D+G+Y
Sbjct: 6550 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 6608
Query: 804 TLK-AENSEGIAETSAVI 820
K + + IA+ +A +
Sbjct: 6609 VAKVVKEKKAIAKYAAAL 6626
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
VE E D W R + P N Y+ RK R +V+D G D++
Sbjct: 5328 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 5385
Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
E P+I++ L + G TFE E++ RWFK E+ ++ L
Sbjct: 5386 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 5444
Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
G KQ L I D DDA EY+C NS T N ++ + +P
Sbjct: 5445 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 5499
Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
A + ++IP + + W K IE+ KF++ +D K TL I + +D E
Sbjct: 5500 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 5559
Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
Y V+ ++ T + V V PP+
Sbjct: 5560 YRVVVENSVGSDSGTVNVTVADVPEPPR 5587
Score = 54.8 bits (126), Expect = 6e-07
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V
Sbjct: 2410 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 2467
Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E
Sbjct: 2468 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 2527
Query: 816 TSAVITV-EEPTEEN 829
+ I V ++PT N
Sbjct: 2528 ATVKINVIDKPTSPN 2542
Score = 53.6 bits (123), Expect = 1e-06
Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y + A N G+++ + + + E P ++ ++ + + ++ +P P
Sbjct: 5364 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5423
Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A +
Sbjct: 5424 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 5481
Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
I + F+ YE ++G+T+ L+ + +W + ++I I +
Sbjct: 5482 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 5541
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
+ D G + +V++ ++ T+ V +PE
Sbjct: 5542 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 5584
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
C L V + +E Y V AVN+ G P +K+K + P +K + ++
Sbjct: 1221 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 1279
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
GE++ + G P P W N KP+KA+ I+K + D G +T+
Sbjct: 1280 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1339
Query: 806 KAENSEGIAETSAVITV 822
+NS G +++A +TV
Sbjct: 1340 TLKNSSGSCDSTATVTV 1356
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P V L + G V FEC++ G PRP+ WF+ + + + + D L+
Sbjct: 5394 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 5452
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
I ++ +DA +TC A N++G S+ L ++
Sbjct: 5453 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 5484
Score = 51.6 bits (118), Expect = 6e-06
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
+ S P+V +G P+++E +++ V + E+ IL+ +V G+P PT W K ++ V +
Sbjct: 436 KTSTPLVPSGASGSA--PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVIS 493
Query: 778 ---LPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEG 812
+DG H++ + K + +DEG YTL EN G
Sbjct: 494 GGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHG 532
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
+I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V
Sbjct: 1817 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 1876
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
V G P P W N KPV + + + + +L+ K G+YTL A N+
Sbjct: 1877 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1936
Query: 812 GIAETSA-VITVEEPT 826
G + S VI + +P+
Sbjct: 1937 GSDKHSVEVIVLGKPS 1952
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
I LP E P V K P F C+ G P P W R +
Sbjct: 4986 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 5045
Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
S ++ + D V I+EV+ DAG +T N G ++T L+V+AP
Sbjct: 5046 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 5096
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V
Sbjct: 1522 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 1581
Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P P + W K N+ ++ L + + H+I + D G Y L +NS
Sbjct: 1582 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 1641
Query: 811 EGIAETSAVITV-EEPTEEN 829
G E A +TV + P++ N
Sbjct: 1642 HGADEEKANLTVLDRPSKPN 1661
Score = 49.6 bits (113), Expect = 2e-05
Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
+TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y
Sbjct: 6326 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 6385
Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
+ Y C A N G+ +T + ++ +P++ + +E
Sbjct: 6386 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 6445
Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
KH G+ A ++G P EV+W +NG +L N + +I+ +T I
Sbjct: 6446 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 6504
Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
S + Y +E + GT+ V V +L V + + P
Sbjct: 6505 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 6538
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
P +L + + G A F ++ + + L+ W +G I S+ + + K L+
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6393
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
I D D G+Y C NS + A LTV ++P +N LR+ + + +
Sbjct: 6394 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 6453
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
V + +V W + + + +K ++ D + + I D Y
Sbjct: 6454 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 6513
Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
+ + S L V + P + G ++++ +W
Sbjct: 6514 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 6573
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
S+ I+K + K + L IK VE D GIY
Sbjct: 6574 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 6608
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
+ SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++
Sbjct: 4950 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 5009
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
+ + + + VG P PT W +N + + SDG + TI +
Sbjct: 5010 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 5068
Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825
+ D G YT++ N G +A + V+ P
Sbjct: 5069 I-DAGEYTVEVSNPYGSDTATANLVVQAP 5096
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/121 (26%), Positives = 48/121 (39%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +KA N G + S + P + + F VK T+ V P P
Sbjct: 3005 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 3064
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
I W+ N +S + + +N + T + DSG YK VA+N +GK H V
Sbjct: 3065 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 3124
Query: 923 I 923
I
Sbjct: 3125 I 3125
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
T V+K Y VVAVN+ G T + E P+ L K V+ GE ++
Sbjct: 3877 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 3936
Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G
Sbjct: 3937 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 3993
Query: 813 IAETSAVITV 822
AE + ITV
Sbjct: 3994 EAEANIKITV 4003
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+
Sbjct: 1507 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 1552
Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
P FI + + ITVK T++ ++ P+P + W++ N+ + +T
Sbjct: 1553 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 1610
Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
D E I + S + D G+Y+ NS G A +T+
Sbjct: 1611 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 1653
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
G + EC + P P+ W FKG +E+V ++ + D VL I ++
Sbjct: 5408 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 5462
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
YT A N G S L+IKT P+V P K ++GE++ L P+
Sbjct: 5463 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 5518
Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
W K+ + ++ +D ++ I + +D G Y + ENS G + +
Sbjct: 5519 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 5577
Query: 821 TVEEPTEENAEPPLF 835
TV + EPP F
Sbjct: 5578 TVADV----PEPPRF 5588
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
+ N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L
Sbjct: 2701 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 2760
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
+ V G P PTITW PV++ + T K+ D G Y +KAEN G
Sbjct: 2761 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 2820
Query: 813 IAETSAVITV 822
+TV
Sbjct: 2821 TDTAEVKVTV 2830
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
K+E + + A NS G E S + E+ P IN ++ITV+ TI++ +
Sbjct: 4275 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 4334
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
NP P I + N I +E D E+VIT S+ D+G YK A+N GK
Sbjct: 4335 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 4392
Query: 916 S 916
+
Sbjct: 4393 T 4393
Score = 45.2 bits (102), Expect = 5e-04
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)
Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S
Sbjct: 2178 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 2232
Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
+ I +K+K+ +P IE R G P K N K +P
Sbjct: 2233 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 2292
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
GDTH T+ K D + +KA NSEG + ET I + P + P
Sbjct: 2293 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 2346
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
+ N+K+ +E + + A N+ G + S P + P++ E L V+ G ++
Sbjct: 2110 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 2169
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
+ G P P +TW N K + + + + + PK + K G YT+ A N G
Sbjct: 2170 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 2229
Query: 813 IAETSAVITVE-EPTE 827
+ I V+ +PT+
Sbjct: 2230 TDSVTINIKVKSKPTK 2245
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
N+K E + V+AVN G + S P +I P+++ + + ++ G + L
Sbjct: 3583 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 3642
Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
+G P PT TW + P D + + +I P K D G Y LK +N G
Sbjct: 3643 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 3702
Query: 815 ETSAVITVEE 824
E + V++
Sbjct: 3703 EAIFEVIVQD 3712
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G
Sbjct: 4265 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 4324
Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
E++ I GNP+P I N P+ + T D + I I K D G Y +
Sbjct: 4325 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 4384
Query: 807 AENSEG 812
A N G
Sbjct: 4385 ATNKYG 4390
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P
Sbjct: 3004 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 3063
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
P+I WF + + + + + DN L + D+G + VA N +G
Sbjct: 3064 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 3115
Score = 41.9 bits (94), Expect = 0.005
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ ++A+N G+ + S + N P + N QEI VK L V+ P P
Sbjct: 2712 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 2770
Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ITW + + S N DG+ V + S D+G Y A N G + +V
Sbjct: 2771 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 2828
Query: 922 TI 923
T+
Sbjct: 2829 TV 2830
Score = 41.5 bits (93), Expect = 0.006
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
KN + +AL D T ++ LK +E + + A N G + S N
Sbjct: 2091 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 2147
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
P + + TVK T+K + + P P +TW N + I S+ +N I
Sbjct: 2148 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 2205
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
SG Y A+N G S VTI+++
Sbjct: 2206 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 2238
Score = 41.1 bits (92), Expect = 0.008
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT
Sbjct: 2458 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 2516
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A NA G +T ++ +++ P S +G
Sbjct: 2517 IKAVNANGEDEATVKINVIDKPTSPNG 2543
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++ + + YP+ + W + I+ + F + DD ATL I ED G +
Sbjct: 5504 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 5562
Query: 584 VAKNAAGFASSTTELIV 600
V +N+ G S T + V
Sbjct: 5563 VVENSVGSDSGTVNVTV 5579
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP F LR + + C ++G P P I W + + +D
Sbjct: 6173 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 6230
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V +L I +DAGT+T A N G S L V+
Sbjct: 6231 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 6268
Score = 39.9 bits (89), Expect = 0.019
Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P KP+ + C V PEP WL G E+ E+ E+ +
Sbjct: 5001 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 5058
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
Y +K V G YTV N G + L ++ PP + + + + I+ G+
Sbjct: 5059 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 5112
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
V L G + N + + PT + D H + + V++ G Y
Sbjct: 5113 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 5172
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G A T + V E + PL I+ T T+ VT ++
Sbjct: 5173 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 5227
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+S E +T + +++ ++T + E +++ A N G
Sbjct: 5228 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 5272
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
++ E+ + I E ++ V P+ + P + + +TV E T L +V+ +P P+
Sbjct: 425 MRRESVQEILEKTSTPLV--PSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTF 482
Query: 865 TWYRNNEIISPSETITQNFDGE--NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
W++ + + DG+ + L + S+ D G Y N G S ++
Sbjct: 483 RWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQ-DEGPYTLTIENVHGTDSADVKLL 541
Query: 923 IDVEKVTFVKHLQKSYETEEG 943
+ + + + K E++ G
Sbjct: 542 VTSDNGLDFRAMLKHRESQAG 562
Score = 39.1 bits (87), Expect = 0.034
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T
Sbjct: 1873 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 1929
Query: 583 CVAKNAAGFASSTTELIV 600
A NA+G + E+IV
Sbjct: 1930 LTATNASGSDKHSVEVIV 1947
Score = 39.1 bits (87), Expect = 0.034
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N
Sbjct: 6198 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 6256
Query: 1652 GTSSVEVTLKVYDKPSKP 1669
G E L V K +P
Sbjct: 6257 GVDVSECVLTVQTKGGEP 6274
Score = 38.7 bits (86), Expect = 0.045
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
++ + E ++K P+ S AP VE + T C+V G P P WF
Sbjct: 427 RESVQEILEKTSTPLVPSGASGS-APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWF 485
Query: 545 RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + + F+ D ++ L + + +D G +T +N G S+ +L+V
Sbjct: 486 KGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV--- 542
Query: 604 LSDHG 608
SD+G
Sbjct: 543 TSDNG 547
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 4/126 (3%)
Query: 1255 IRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
IR+ + D + E +L+ ST + PKIV+ + L
Sbjct: 418 IRRSSIDMRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGS 477
Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCG--HAD 1370
P P W S+ + K D K + +L + K + D G Y L +EN G AD
Sbjct: 478 PAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSAD 537
Query: 1371 VEMNVT 1376
V++ VT
Sbjct: 538 VKLLVT 543
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
+ +K Q + V A+N+ GE+ S P + P++ + + V+ G+++
Sbjct: 2994 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 3053
Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
V G P P I W N P+ + T D +T + T L K D G Y + A N
Sbjct: 3054 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 3113
Query: 811 EGIAETSAVITV 822
G E + +
Sbjct: 3114 SGKDEHEVDVNI 3125
Score = 37.5 bits (83), Expect = 0.10
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
KS+ D H + KP K V+D E +Y +KA N G + + + A
Sbjct: 1206 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 1265
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P +++ +K TIK ++ P+P W N + + + + + +
Sbjct: 1266 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 1325
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I N DSG + NS+G A VT+
Sbjct: 1326 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 1356
Score = 37.1 bits (82), Expect = 0.14
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT--KEKTSVIRIKELKRSHSSKYTIEAS 1648
++T + G P P W+K ++ + + T KE T + + + + YT+
Sbjct: 469 ILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIE 528
Query: 1649 NTAGTSSVEVTLKV 1662
N GT S +V L V
Sbjct: 529 NVHGTDSADVKLLV 542
Score = 37.1 bits (82), Expect = 0.14
Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y
Sbjct: 6454 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 6512
Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+L + + V V + +K PP + + SS P G ST + +
Sbjct: 6513 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 6559
Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
E++ ++ T +W + ++++KT ++++ V + D + KV+K
Sbjct: 6560 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 6614
Query: 1476 ETK 1478
E K
Sbjct: 6615 EKK 6617
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+E + + A N G ++ S N +P + + + +T+K +I V+
Sbjct: 2410 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 2469
Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+
Sbjct: 2470 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 2527
Query: 917 HGARVTIDVEKVT 929
++ + ++K T
Sbjct: 2528 ATVKINV-IDKPT 2539
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
L+N + N +LTC G P P + W +DG + + R
Sbjct: 6185 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 6244
Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
Y A ND G + CV+ +Q K
Sbjct: 6245 AGTYTVTATNDLGVDVSECVLTVQTK 6270
Score = 36.3 bits (80), Expect = 0.24
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++
Sbjct: 1550 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 1609
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
+ + L I D G + KN+ G L +++ P +G
Sbjct: 1610 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 1662
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PP V W+K+ +L+ +Y + I +K +YT+ A N+ GT V L
Sbjct: 6084 PPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 6143
Query: 1661 KV--YDKPSKPE 1670
V + +P K E
Sbjct: 6144 NVTRHSEPLKFE 6155
Score = 35.5 bits (78), Expect = 0.42
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVK 845
H +T L PKK + V A + S IT + PT + ++I
Sbjct: 4562 HRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLT---RDILAY 4618
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDY 904
K++ +P P +T+ + ISP++ + + + +T SE+ D G Y
Sbjct: 4619 AGERAKILVPFAASPAPKVTFSKGENKISPTDPRVK-VEYSDFLATLTIEKSELTDGGLY 4677
Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
NS G S R+ + V+K +H++
Sbjct: 4678 FVELENSQGSDSASIRLKV-VDKPASPQHIR 4707
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++++ + G P P+ W +K +M + + I D+G FT
Sbjct: 1281 GETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMS-SERGKHIMKIENAVRADSGKFTI 1339
Query: 584 VAKNAAGFASST-TELIVEAPLSDHG 608
KN++G ST T +V P G
Sbjct: 1340 TLKNSSGSCDSTATVTVVGRPTPPKG 1365
Score = 34.7 bits (76), Expect = 0.73
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 499 EKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDF 556
++ ++ +++AP I E L G+T++F ++G P P +TW F I +
Sbjct: 2139 DRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQI 2198
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
+ ++ ++ + + + +G +T A N G S T + V++
Sbjct: 2199 E---NEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKS 2241
Score = 33.5 bits (73), Expect = 1.7
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G V G P P ITW F T + S D ++D ++ D GT+
Sbjct: 2755 GQDFSLNIPVSGEPTPTITWTFEGTPV--ESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 2812
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A+N G ++ ++ +++ P S G
Sbjct: 2813 IKAENENGTDTAEVKVTVLDHPSSPRG 2839
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/97 (21%), Positives = 34/97 (35%), Gaps = 2/97 (2%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P + P+ V E +L C++ P P W E++ + H
Sbjct: 448 GSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHT 507
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
L + + EG YT+ N G S + L +
Sbjct: 508 V--ALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 542
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+PP + + V G D L + P P I W F+G + D+ + + E
Sbjct: 2738 VPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTK 2797
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
+ + + GTY + A N G + + + + P
Sbjct: 2798 F----HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSP 2837
Score = 31.9 bits (69), Expect = 5.2
Identities = 12/42 (28%), Positives = 22/42 (52%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
+P + + +N+T NE LTC G P P W++ +++
Sbjct: 450 APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREV 491
>Z73897-5|CAA98065.2| 7158|Caenorhabditis elegans Hypothetical protein
ZK617.1b protein.
Length = 7158
Score = 318 bits (782), Expect = 2e-86
Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)
Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
+K+ + + K +C S +WY ++KEI SG +I+ E
Sbjct: 1135 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 1194
Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
D G C T L V E + F+ L + E+ A+L ++N+ A +VW
Sbjct: 1195 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 1254
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
R + I+ ++ EK R L I+ D+ E++ I +D +V V E
Sbjct: 1255 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 1314
Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
+ +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I
Sbjct: 1315 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 1374
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
++D GEY C + + A L V+ + F + L + ++ + D L + D
Sbjct: 1375 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 1432
Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
W++ I KF S TL I K ++ Y + + + V
Sbjct: 1433 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 1492
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
E P + ++ K G + V +Q P + + N K I + K + I
Sbjct: 1493 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 1552
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
A + K + D G + L L N+ G A + + DKP PP P + + +
Sbjct: 1553 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 1612
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N
Sbjct: 1613 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 1672
Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
E +SD E+ Y K + + V+K + EP E+ I G +
Sbjct: 1673 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 1732
Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
+ + W++ G+ T K E++ C DHG+
Sbjct: 1733 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 1785
Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
+ +K + IK + KVG+ I G P PE +W NG L+ +
Sbjct: 1786 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 1844
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
+++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ +
Sbjct: 1845 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 1904
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR
Sbjct: 1905 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 1964
Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
V A N G SE L ++ IK D P D + + I W P K+GG+PI
Sbjct: 1965 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 2023
Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
+Y VE++ + K+WK A I L YQFR+ A N+ G P +K
Sbjct: 2024 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 2083
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
P + + S + T++W GG PI E K KG +
Sbjct: 2084 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 2137
Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
+T+ +EH CI + D +R++ +N+ G + +V L++ PS P P
Sbjct: 2138 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 2192
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L
Sbjct: 2193 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 2250
Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+ TY R+ A N+ G S+ L +D+ K
Sbjct: 2251 KGQTYQFRVKAVNKEGASDALSTDKDTK 2278
Score = 253 bits (619), Expect = 1e-66
Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)
Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
P ++D +E ++K G D +L + P P W ++ K + +
Sbjct: 3268 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 3327
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
+K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP
Sbjct: 3328 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 3387
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD
Sbjct: 3388 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 3447
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
E E + K+ ++ P + + D++ T GG P V
Sbjct: 3448 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3506
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
A ++ A N GE + S + + + + N
Sbjct: 3507 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3566
Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K
Sbjct: 3567 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3626
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG
Sbjct: 3627 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 3686
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L
Sbjct: 3687 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 3743
Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
S+ IV K D P D + V + W P +GG+PI Y VE K + W
Sbjct: 3744 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 3802
Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
A L+ TYQFR+ A N+ G P + P
Sbjct: 3803 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 3862
Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ +K +P+ + T+ + + S H ++
Sbjct: 3863 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 3922
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
D +++I EN G + +V VP P PL+I + +W P
Sbjct: 3923 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 3976
Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
+GG +L Y + D ++ W EVG T K N L Y R+ A N G S+
Sbjct: 3977 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 4034
Query: 2052 PLESDEP 2058
PLE++EP
Sbjct: 4035 PLEAEEP 4041
Score = 251 bits (614), Expect = 5e-66
Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
PKI+ R+ +IK G L VD+ P P W V S + S+
Sbjct: 4150 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 4209
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
+ D+G YKL+++N G + V + D+PS P P + ++ S + W P++
Sbjct: 4210 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 4269
Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+
Sbjct: 4270 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 4329
Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
T E V+ + +P KP + I N+ I++ GG P R D
Sbjct: 4330 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 4385
Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
K + K Y+ +A N G + S + + P
Sbjct: 4386 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 4445
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
+ + + + K G+ ++T P P++ W K G K E TT +T ++
Sbjct: 4446 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 4501
Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
I +RS S I+A N G + + + V DKP PE + +SR + T+ W P
Sbjct: 4502 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 4560
Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+
Sbjct: 4561 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 4619
Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
+ P+VIK D P D V + W P +GGSPI+ Y VE K+
Sbjct: 4620 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 4678
Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
G W + L N TYQFR+ A N G P + +T + P
Sbjct: 4679 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 4738
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
P V + T S L W P +GG+PI YI+E K + WT+ +
Sbjct: 4739 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 4798
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
+N+ EK+E FR+ A N+ G P++ S V +E+ P
Sbjct: 4799 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 4838
Score = 250 bits (612), Expect = 8e-66
Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y
Sbjct: 2399 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 2457
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
L N G + V +L KPS P G + + ++ W PE+ G + I +Y +
Sbjct: 2458 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 2517
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ +
Sbjct: 2518 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 2575
Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
+ P V+KP + + D+ GG P + K + + A ++
Sbjct: 2576 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 2635
Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
++ A N G + S VV + I ED+ KVG
Sbjct: 2636 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 2695
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
I+G P P+V W NG + K I + S + + R S KYTI A+
Sbjct: 2696 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 2754
Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK
Sbjct: 2755 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 2814
Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
+ W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D
Sbjct: 2815 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 2871
Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
P D++ V + W P +GG+PI +Y++E + + +W+ A
Sbjct: 2872 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 2930
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
+ L+ N Y+FR+ A N+ G S P + + P R+ + + + ++
Sbjct: 2931 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 2990
Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
+ P S +P +T + + + ++ K+ + ++ ++ D F I A
Sbjct: 2991 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 3049
Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I
Sbjct: 3050 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 3104
Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
D W+ KV + + L H Y R+ A N G S+PLE+
Sbjct: 3105 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 3156
Score = 243 bits (595), Expect = 1e-63
Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
R+K G + V+ + P P EW +N + +T ++ + LT K D+G
Sbjct: 3574 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 3633
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y
Sbjct: 3634 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 3693
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
VVE QE D W+ + T + L Y+FR AVN S + T + ++
Sbjct: 3694 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 3750
Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
+ P + + + + D+E GG P + +D G ++ A+
Sbjct: 3751 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 3810
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
+ ++ A N G + S G + KP ++ +
Sbjct: 3811 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 3869
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
K G + EG P P W N ++ ++T +S I I R + Y
Sbjct: 3870 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 3929
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E
Sbjct: 3930 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 3989
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K
Sbjct: 3990 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 4047
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
DVP D + + I W P+ NGG+P+ Y VE K++G W
Sbjct: 4048 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 4106
Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
L Y+FR+ A N G S P +D +IT + L P + R + +
Sbjct: 4107 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 4166
Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
++ + + P + + + + +V S + K D ++
Sbjct: 4167 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 4221
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
+ +N +G E +++ PS P PLE+ V + + +W P+ DGGA +
Sbjct: 4222 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 4276
Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP
Sbjct: 4277 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 4334
Score = 242 bits (593), Expect = 2e-63
Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+K G+ + +V P P+ W N K I + K + + + + K +G Y
Sbjct: 2691 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 2749
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+ N G V +N+ + KP+ P P + ++ + W PE+ G I +Y +
Sbjct: 2750 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 2809
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E W+ T ++ +L Y+FR AVN SD ET ++ +
Sbjct: 2810 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 2867
Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
P ++P + T+ + D ++L GG P + + K + + A
Sbjct: 2868 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 2925
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
+ ++ +A N G + S V+ + I + +K K
Sbjct: 2926 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 2985
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + G P P V W+ N+ + N + E S + +K+++R S +T
Sbjct: 2986 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 3045
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE
Sbjct: 3046 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 3105
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K
Sbjct: 3106 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 3165
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
D P D + V + W P +GG+PI +Y VE+K E W
Sbjct: 3166 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 3224
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A + L + Y+FRI A+N+ G P S + + + PP RN +
Sbjct: 3225 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 3283
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
P S +P + E V+ K+ G H ++ D + I
Sbjct: 3284 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 3342
Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
AEN G T V + H PS P PL++ + + +W PE DGGA +
Sbjct: 3343 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 3397
Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E
Sbjct: 3398 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 3452
Score = 235 bits (575), Expect = 3e-61
Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)
Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
+ RIK G+ + L + ++ P P +W N I + S+++ I D
Sbjct: 3866 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 3925
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++
Sbjct: 3926 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 3985
Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
Y+VE + W V + L Y FR AVN S E E
Sbjct: 3986 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 4045
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
+ + P V+KP + DI+ T GG P VT Y KK K + E
Sbjct: 4046 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 4101
Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
++ IA N G + S Q KP I ++ IK
Sbjct: 4102 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 4161
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
K V + G P P W + E + K T+ I KR+ S
Sbjct: 4162 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 4219
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y
Sbjct: 4220 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 4279
Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
+EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K
Sbjct: 4280 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 4338
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
P DN+ + I W P NGGSP+ Y +E K + G+ K
Sbjct: 4339 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 4397
Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
A R+QK TY++R+ A N+ G P S T P +
Sbjct: 4398 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 4454
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
F V +T+ +T SP + I + GK + T S + I +
Sbjct: 4455 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 4505
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
+ D +I A N G + ++++ TV P AP I V + +W
Sbjct: 4506 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 4557
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G
Sbjct: 4558 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 4616
Query: 2049 LSE 2051
LS+
Sbjct: 4617 LSD 4619
Score = 234 bits (572), Expect = 6e-61
Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + +K G+ V V P P +W N ++ + T + ++ L I
Sbjct: 2096 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 2155
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
+D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G
Sbjct: 2156 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 2215
Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T
Sbjct: 2216 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 2274
Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
K+TK ++P ++P K T + + D + + P+ +T Y KK K
Sbjct: 2275 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 2328
Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
+ E ++ ++ A N G E S VV +
Sbjct: 2329 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 2388
Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++
Sbjct: 2389 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 2447
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD
Sbjct: 2448 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 2507
Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
GG + Y IEK + RW+ + T + L EY FRV A N G S+ L
Sbjct: 2508 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 2565
Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
+ I+ K +VP D + V + W + +GG+PI + +E K + +
Sbjct: 2566 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 2623
Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
W+ A + L YQFRI ARN+ GT P D++ P R
Sbjct: 2624 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 2683
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+ + TLK+ +P + K + G+S +I + +
Sbjct: 2684 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 2741
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
K + I+A N G T+S ++ + K + P+ P P+E+ V + W P
Sbjct: 2742 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 2796
Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S
Sbjct: 2797 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 2854
Query: 2051 EPLESD 2056
+PLE++
Sbjct: 2855 DPLETE 2860
Score = 223 bits (545), Expect = 1e-57
Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + IK G ++ V P P W +++ I+ K + L +K++
Sbjct: 2977 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 3036
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G
Sbjct: 3037 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 3096
Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
I YV+E + + W+ + KT + L Y+FR V V+ S+
Sbjct: 3097 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 3153
Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
E + T + +KP K IT + ++L GG P + V +D
Sbjct: 3154 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 3209
Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
+ ++ A N G S V + P
Sbjct: 3210 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 3269
Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
+ N + K K G ++ + + G P P + W G +E+D + ++ + +
Sbjct: 3270 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 3329
Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D
Sbjct: 3330 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 3389
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+
Sbjct: 3390 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 3447
Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
LE+ E I+ K D + D + + W P +GG+PI Y VE++
Sbjct: 3448 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3506
Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
W A + L TYQFR+ A N+ G S P + P
Sbjct: 3507 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3566
Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
R+ V++ TL + +P + + + T I + + ++
Sbjct: 3567 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3626
Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
D ++I A N G + V + +P P PL + + V+ W
Sbjct: 3627 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 3681
Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G
Sbjct: 3682 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 3738
Query: 2050 SEPLESD 2056
S PL SD
Sbjct: 3739 SAPLTSD 3745
Score = 209 bits (510), Expect = 2e-53
Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)
Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
++ ++ G + + + Y P+P + + I + + T ++ +T + +
Sbjct: 4846 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 4905
Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I
Sbjct: 4906 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 4965
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET +
Sbjct: 4966 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 5022
Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
++ + +P +P T+E ++ T GG P Q V R+ + KA
Sbjct: 5023 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 5082
Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
+ N Y + A+N G+ E S + P N + +
Sbjct: 5083 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 5142
Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
+ G+ + P P+V + K NK+ D + + + + I++ + +
Sbjct: 5143 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 5202
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T
Sbjct: 5203 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 5261
Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++
Sbjct: 5262 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 5320
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
+V K +VP+ D+ + W P ++GGS II Y+V+ + +W
Sbjct: 5321 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 5378
Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
AR+ L N ++FRI A+N G S P ++ + PP P +
Sbjct: 5379 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 5438
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
T+ W P +GGS IT Y +E + WT E ++ ++E
Sbjct: 5439 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 5498
Query: 1934 DEIIFRISAENTVGVSLPT 1952
++ FR+ A N G +P+
Sbjct: 5499 NDYEFRVVAINAAGKGIPS 5517
Score = 199 bits (485), Expect = 2e-50
Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
+D + +L + + N ++++ NN G ++ + I D +P PG+P I +
Sbjct: 1943 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 2002
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F
Sbjct: 2003 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 2062
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
R AVN+ SE +E ++ K I + LK+IT + + GG P P
Sbjct: 2063 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 2121
Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
+V W++ ++L+ + T + R Y+ N HG E +
Sbjct: 2122 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 2181
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
+ +P + N ++ D ++ E I Y KL+ + K
Sbjct: 2182 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 2239
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
K + I LK+ + ++ ++A N G S T K YD+P K P ++ +
Sbjct: 2240 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 2298
Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
+ V++EW+PP DGG +T+Y IEK W + V D I L E EY F
Sbjct: 2299 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 2358
Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
RV A N G EA + S +V K P ID E++ + K G
Sbjct: 2359 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 2405
Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
D V + KK W RI+ T + R R G T+ +
Sbjct: 2406 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2465
Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
DK ++ L PS P VS L+W PE +GG+PI +Y IE +
Sbjct: 2466 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 2525
Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
W V G S + + N++ E FR+ A N G S P + + L K+ VP
Sbjct: 2526 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 2582
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
P E+ + V +W P+ DGGAP+ + I +D W E V + +
Sbjct: 2583 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 2639
Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+L E Y RI ARN+ G +P + +
Sbjct: 2640 PNLKEGEEYQFRISARNKAGTGDPSDPSD 2668
Score = 191 bits (465), Expect = 5e-48
Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)
Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
W + ++D +K + S+ K ++R T YT +A + K VEV+
Sbjct: 2421 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 2479
Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
P ++ Y + +D+ V P D + + + + P S++
Sbjct: 2480 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 2536
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
T+ ++ +++R N G +D + N IL K P KP +++ D +
Sbjct: 2537 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 2596
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A
Sbjct: 2597 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 2654
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT
Sbjct: 2655 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 2712
Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
W +GK + +KA EN Y A N +G + + ++ KP
Sbjct: 2713 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 2772
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
K +V D + A ++ PP + + +Y+ D + +
Sbjct: 2773 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 2826
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
+ + L + K+ ++A N+ G S ++ K +D+P +P P +
Sbjct: 2827 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 2885
Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
+ V ++W PPL DGG + +Y IEK RW V T + L N EY FR
Sbjct: 2886 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 2944
Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
V+A N G S+ ++ VI ++ I++ +P +
Sbjct: 2945 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 3004
Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
+ +E G + K ++++ + F I A N G + KI
Sbjct: 3005 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 3061
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
+ T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W
Sbjct: 3062 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 3118
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
V G ++ + E FR++A N G S P E+ L K P AP EI
Sbjct: 3119 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 3177
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ V W P DGGAP+ Y + ++D W +V V + +L E
Sbjct: 3178 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 3237
Query: 2036 TYMIRIYARNEIGLSEPLES 2055
Y RI A+N+ GL +P +S
Sbjct: 3238 KYEFRIRAKNKAGLGDPSDS 3257
Score = 190 bits (463), Expect = 9e-48
Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI
Sbjct: 4586 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 4644
Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N
Sbjct: 4645 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 4704
Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+Y+FR AVN + S +E V K +P V K KN + E + L
Sbjct: 4705 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 4763
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
GG P + + KKL T N ++ IA N GE
Sbjct: 4764 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 4819
Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
E S +V I++ +P+ I+N +DI + G+ + G P +I NGN
Sbjct: 4820 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 4877
Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
EN++ + VI KRS + Y I A+N G + ++ + V D P KP
Sbjct: 4878 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 4936
Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++
Sbjct: 4937 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 4993
Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
L+ N Y FRV A+N G E LE+ + IV K D P E++ + W
Sbjct: 4994 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 5052
Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
+GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N
Sbjct: 5053 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 5112
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
G + IT T P + + + K P + +P +
Sbjct: 5113 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 5172
Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ V + IE + D ++ + EN+ G ++S S+RL+
Sbjct: 5173 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 5224
Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
V P +P IR+ + + W P DGG+P+ Y + D+ + W +V
Sbjct: 5225 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 5283
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
V L + + L +++ Y R+ A + G+SEP E
Sbjct: 5284 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 5317
Score = 183 bits (445), Expect = 1e-45
Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I
Sbjct: 4301 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 4360
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
+I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A
Sbjct: 4361 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 4420
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
VN+ S+++ + ++P + L K + E + +T F PQP +
Sbjct: 4421 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 4478
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
+W ++G K T +++ K A N +GE E + + + KP
Sbjct: 4479 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 4538
Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
+ +H W G E+ YK + + ++ + +
Sbjct: 4539 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 4595
Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
++ L+ ++ I A N G S V V +K +D P P P I + + V++
Sbjct: 4596 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 4654
Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A
Sbjct: 4655 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 4713
Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
N G E SEP+ + ++ P N S +TW ++GG+PI Y
Sbjct: 4714 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 4772
Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
VE K+ G W ++ L Y+FR+ A N G P D + I
Sbjct: 4773 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 4832
Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
+ P N + + T++ P + G PI + + T +V V
Sbjct: 4833 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 4891
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
K D ++ISA N G + V P PT P+ +
Sbjct: 4892 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 4946
Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y
Sbjct: 4947 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 5003
Query: 2040 RIYARNEIGLSEPLESDE 2057
R+ A N+ G+ EPLE+D+
Sbjct: 5004 RVRAENQYGVGEPLETDD 5021
Score = 178 bits (434), Expect = 3e-44
Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D P P KP + + D I+I W+ N G + + Y+VE +E + W T
Sbjct: 4049 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 4108
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S NLK Y FR AVN SD S+ T+ I + + P + + I +
Sbjct: 4109 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 4166
Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
L F G P P TW D + + + YK N
Sbjct: 4167 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 4226
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ GE E V +Q +P + +V D + V+ PP + + N +
Sbjct: 4227 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 4280
Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
++ T S I + +L H ++ + A NT G S S+ V K
Sbjct: 4281 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 4340
Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV
Sbjct: 4341 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 4399
Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
+ ++ + Y +RV+A N G + +S K + P
Sbjct: 4400 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 4459
Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
E + IT P SP D + +EG K + I + +
Sbjct: 4460 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 4513
Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
+I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I
Sbjct: 4514 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 4567
Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S +
Sbjct: 4568 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 4625
Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
V ++ P P+ P EI +N V +W P DGG+P+LGY + W
Sbjct: 4626 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 4684
Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
V V + + L EN TY R+ A N G EP EP P
Sbjct: 4685 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 4732
Score = 176 bits (428), Expect = 2e-43
Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+I+ + ++ +A F E + + RW ++G E+ S+ + K I
Sbjct: 5533 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 5592
Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
+ DAGEY+ EV G+ TA L V+ P + +P IL + Y +
Sbjct: 5593 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 5651
Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
P V ++ + T + D T+ E + EYT ++TT
Sbjct: 5652 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 5711
Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ V P + I T + ++ P + + S +++K +K
Sbjct: 5712 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 5765
Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
+ + + +K + G+ Y+ R+ EN G V + I P PP P
Sbjct: 5766 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 5825
Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
I+++ + + W P + G + Y+VE QE + EW + + NL
Sbjct: 5826 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 5885
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
YR+R +AVN+ +SD +E + + + P + PL ++ E + C
Sbjct: 5886 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 5944
Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
G P+P+ W++ K+L T+K T N+ Y C A N G
Sbjct: 5945 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 6004
Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
T + I+ KP + I + + + G+ + + P E W K+G K+EN+ +
Sbjct: 6005 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 6064
Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I
Sbjct: 6065 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 6123
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y
Sbjct: 6124 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 6180
Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
FR+IA+N G S+ E + P++I
Sbjct: 6181 EFRIIAENKHGQSKPCEPTAPVLI 6204
Score = 171 bits (416), Expect = 5e-42
Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)
Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+++R N GH + VT ++KP P P + +I +S + W+ P G +
Sbjct: 4708 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 4767
Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++
Sbjct: 4768 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 4827
Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
V+ E + P + LK+IT E I++ + GG P+P + + + +
Sbjct: 4828 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 4885
Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
T YK A N +G+ V+ KP I DI
Sbjct: 4886 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 4945
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
Q + W G + I K ++ + +R++ L +
Sbjct: 4946 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 5000
Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
++ + A N G T V +D P P P + E S E++T++W P DG
Sbjct: 5001 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 5059
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
G + Y IEK E + W K A + + + L Y FRV A N G E ++
Sbjct: 5060 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 5119
Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
S PI A P + +P + + +I
Sbjct: 5120 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 5179
Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
+ K I+K + + + N G SD K + P+ P+
Sbjct: 5180 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 5233
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
+ V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + +
Sbjct: 5234 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 5292
Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
+ + + FR+ AE GVS P E V + K+ VP+ P AP +R S W
Sbjct: 5293 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 5351
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N
Sbjct: 5352 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 5409
Query: 2047 IGLSEPLESDE 2057
G S+P E
Sbjct: 5410 AGFSKPSPPSE 5420
Score = 163 bits (396), Expect = 1e-39
Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++
Sbjct: 1647 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 1704
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
+D + W+ PE G + I Y++E +E +W V + + K + Y
Sbjct: 1705 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 1764
Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
+R AVN+ D + + K+ K K +K++ + E I+ G P
Sbjct: 1765 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 1823
Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
P+ W +GK LK ++ + + N G +++ V
Sbjct: 1824 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 1883
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
+ +P DI G + P + ++N +Y K
Sbjct: 1884 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 1943
Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I +
Sbjct: 1944 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 2002
Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
+ + I W+PP DGG + +Y +E +PD W +V V D I L E EY
Sbjct: 2003 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 2060
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
FRV A N G + E + +P+ + W K GG
Sbjct: 2061 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 2118
Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
PI + K +++ + I + ++R+ +N G
Sbjct: 2119 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 2174
Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+
Sbjct: 2175 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 2232
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
W V + H I+ +K+ FR+ A N G S + K+ T
Sbjct: 2233 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 2289
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
++ ++ V W P+ DGGAP+ Y I + W E GKV + I
Sbjct: 2290 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 2349
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
L E Y R+ A N+ G E SD KV+
Sbjct: 2350 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 2379
Score = 142 bits (343), Expect = 3e-33
Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
P PP I + I W P G S I Y VE +E +T W S N+ + +
Sbjct: 5431 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 5490
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
++ L+ + Y FR A+N S + K+ + + V KP T +P N
Sbjct: 5491 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 5548
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
TC G P+P W R+G++L ++++ +E Y
Sbjct: 5549 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 5608
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
N +G + + +Q PVI +D+ GD + G P N +
Sbjct: 5609 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 5665
Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
++ D I + +I I L + +Y SN +G ++ L V P P+G
Sbjct: 5666 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 5725
Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L
Sbjct: 5726 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 5784
Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
EN EY FRV AQN G L SE PI+ + D P + + V ++W
Sbjct: 5785 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 5843
Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
+GG + Y VE ++E +W + L Y++R++A N+ G
Sbjct: 5844 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 5903
Query: 1848 S 1848
S
Sbjct: 5904 S 5904
Score = 132 bits (320), Expect = 2e-30
Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)
Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
K T KL V V++ P K R I+ + + + ++ P+ N + + +++K
Sbjct: 4920 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 4975
Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
+ T +V N DA +++R EN G + +E + I+ D P P
Sbjct: 4976 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 5035
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ +
Sbjct: 5036 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 5095
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
L +Y FR A N + S + + + P + + ++I E +
Sbjct: 5096 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 5153
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
+ F P PKVT+ + K+ K Y + Y N
Sbjct: 5154 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 5213
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
G S + + KP S + I+ + D W+ + G P I K
Sbjct: 5214 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 5270
Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
+ + K +++ + + L + + ++ + A G S V V ++
Sbjct: 5271 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 5330
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D +
Sbjct: 5331 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 5387
Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
+ + L +N E+ FR+IA+N GFS+ + SE +K+ P I
Sbjct: 5388 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 5446
Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
ITW ++GGS I Y VEI++ G W + KL Y+FR+
Sbjct: 5447 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 5506
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A N G +P I I + + S+P+ V E T++
Sbjct: 5507 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 5544
Score = 129 bits (311), Expect = 2e-29
Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ +
Sbjct: 5316 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 5374
Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
WI+ K Q + L+ N + FR A N S S +E ++ P
Sbjct: 5375 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 5434
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
+ K+I + + G K+T Y R+ G L T + Y R
Sbjct: 5435 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 5492
Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
++ +A N G+ S G IQ+ +P I + ED Q + +
Sbjct: 5493 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 5552
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
AV G P P W +NG +L Y + IKE+ + +YT+E SN
Sbjct: 5553 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 5610
Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
G+ + L V P PVI +++ TI L G L K P
Sbjct: 5611 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 5656
Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
+ + ++D D T I + +++ ++ G E S T L+V
Sbjct: 5657 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 5716
Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
P I + ++W P +GGS I Y VE + K +W
Sbjct: 5717 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 5776
Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
I L N Y+FR+ A+NE G P S+ I PP+ P N + +
Sbjct: 5777 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 5836
Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
VTL W P S+GG + YI+E + + W + + + + N+ + + +R+
Sbjct: 5837 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 5896
Query: 1942 AENTVGVS 1949
A N G+S
Sbjct: 5897 AVNDAGLS 5904
Score = 124 bits (299), Expect = 7e-28
Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)
Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
W P +GGSPI +Y K++++ KW K + L + Y+FR+ A
Sbjct: 5249 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 5308
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
+ G S P D + P+QP V + S L+W +P +GGS I Y ++
Sbjct: 5309 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 5367
Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
++ W + + E C + +++ E FRI A+N G S P+ S+ +L
Sbjct: 5368 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 5424
Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
+ P PP + + +G N +W P DGG+ + GYN+ IR+ T+W
Sbjct: 5425 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 5483
Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
+V +F + L E + Y R+ A N G P P K+ GS
Sbjct: 5484 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5531
Score = 99 bits (238), Expect = 2e-20
Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)
Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P I WY++ + I + +N+ +I N D+G Y C A+ G +H
Sbjct: 1155 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 1211
Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
++ K +F+ L + E K +L C+ + WY K I D R II+
Sbjct: 1212 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 1271
Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
+ GR I +D + + V+E F+ ++ +V E D+A
Sbjct: 1272 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 1331
Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+
Sbjct: 1332 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 1391
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
A++ +V+ + I L++ +V + + T + WF++G +I
Sbjct: 1392 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 1450
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+ LKI ++++A Y + + + +TV E
Sbjct: 1451 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 1491
Score = 99.1 bits (236), Expect = 3e-20
Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)
Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ +
Sbjct: 1595 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 1652
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
++++KE E FR+ A N G+S P +SV + VP P ++ V +
Sbjct: 1653 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 1711
Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
+W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A
Sbjct: 1712 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 1771
Query: 2045 NEIGLSEPLESDEPFKV 2061
N+ G +P + +P K+
Sbjct: 1772 NKAGPGDPCDHGKPIKM 1788
Score = 98.3 bits (234), Expect = 5e-20
Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
+S + TL W P ++GGS IT+Y++E + + W VTV +V + + + +
Sbjct: 5729 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 5785
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW
Sbjct: 5786 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 5842
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P DGG L GY + ++ W + +N+ +L + Y R++A N+ G
Sbjct: 5843 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 5902
Query: 2049 LSEPLESDEPFKVIPGEG 2066
LS+ E D+ G G
Sbjct: 5903 LSDLAELDQTLFQASGSG 5920
Score = 94.3 bits (224), Expect = 9e-19
Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)
Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
L D+ +T+ K + L +H ++ + A N G S + ++ +D P
Sbjct: 5762 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 5821
Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
+ P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y
Sbjct: 5822 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 5880
Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
+ L + +Y +RV A N G S+ E + + + A ++ E
Sbjct: 5881 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 5939
Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
F E + GSP +Y+ + + K+ I L+ + ++ A
Sbjct: 5940 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 5998
Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
N GT + T + PP + + T++ P +
Sbjct: 5999 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 6054
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + ++ S I T I N +D +R+ EN+VG T + +V
Sbjct: 6055 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 6108
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K
Sbjct: 6109 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 6167
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
I L Y RI A N+ G S+P E P +IPG+
Sbjct: 6168 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 6207
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
T LDVP I E + W P NGG+ ++ Y VE + W+
Sbjct: 3946 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 4005
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A++ KL Y FR+ A N G S P +++ I P V++
Sbjct: 4006 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 4065
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
+ +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+
Sbjct: 4066 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 4123
Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
A N G S P++ ++ K + P TA +I++ N+ + G P+
Sbjct: 4124 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 4178
Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
P + + + V K ++ F +++ Y +++ +NE+G E
Sbjct: 4179 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 4231
Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
+ F+VI + A E P E ++V
Sbjct: 4232 EAIFEVIVQDRPSAPEGPLEVSDV 4255
Score = 88.6 bits (210), Expect = 4e-17
Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ +
Sbjct: 6582 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 6640
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
+TI + K D+G YT++A+NS G E + V +E PL E K
Sbjct: 6641 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 6693
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
++ R P T++ N +I + +T + G + D D
Sbjct: 6694 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 6753
Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
V+ S S +D + T+ + + V+ TV TK
Sbjct: 6754 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 6805
Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
+S R + + G +I+ + D + + L K T +P F
Sbjct: 6806 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 6865
Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
+L D E + A ++ + ++ W +GE I +++ L I +
Sbjct: 6866 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 6925
Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
DEG+Y C + E A +TV VE + L + VN
Sbjct: 6926 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 6985
Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV
Sbjct: 6986 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 7045
Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
+ +++ V E + RLP + P T+E + E L V W++
Sbjct: 7046 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 7105
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
IE E+ + L I+ +DD Y ++ K
Sbjct: 7106 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 7145
Score = 87.8 bits (208), Expect = 7e-17
Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S
Sbjct: 5946 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 6005
Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
L++ KP P +++ TIE K P ++ + + +NN
Sbjct: 6006 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 6065
Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
+ D+ T I + +RV+ +N VG V T DVP
Sbjct: 6066 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 6119
Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
+D E+V ++W P +GGS + +Y +E ++ G W I+ L
Sbjct: 6120 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 6178
Query: 1834 TYQFRIYARNEIGTSLP 1850
Y+FRI A N+ G S P
Sbjct: 6179 QYEFRIIAENKHGQSKP 6195
Score = 70.5 bits (165), Expect = 1e-11
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
+P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V +
Sbjct: 5719 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 5777
Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
+ + L ENH Y R+ A+NE G+ PL S+ P
Sbjct: 5778 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 5811
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP
Sbjct: 5893 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5952
Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
W CK + GD + I+ D YT +A NS G T A +
Sbjct: 5953 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 6011
Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
++ +P +FI ++ +KG TI+L P W ++ E I +
Sbjct: 6012 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 6065
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ D + L I+N E D G+Y+ V NS G S VT+
Sbjct: 6066 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 6108
Score = 66.9 bits (156), Expect = 1e-10
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ K +G + F C+V P +TW + +K S + Y+ ++ L
Sbjct: 6585 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 6643
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I V +D G +T AKN+ G T E IV ++ H + +
Sbjct: 6644 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 6699
Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
E P F+ + + + + L C L P P I W+ G V ++ + V+
Sbjct: 6700 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 6758
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
S + CS L+I N + GTYTV A N G VL ++T EP P+V
Sbjct: 6759 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 6807
Score = 66.5 bits (155), Expect = 2e-10
Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P+F+ + + G + PEP I WL GE I ++ + +
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 6919
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
L+I++ KK EG Y A N G+ L +K + + +V + L
Sbjct: 6920 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 6979
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
IV GESV A+V G P + W +N + + DG+T S TI D
Sbjct: 6980 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 7037
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
G Y L+ S+G S V E A+PP + R ++ G+
Sbjct: 7038 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 7092
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
++ W+R +E I +E + G +L I NV+ + D G Y
Sbjct: 7093 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 7137
Score = 62.9 bits (146), Expect = 2e-09
Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
E P L G S SA V G P P I W N + + ++ T
Sbjct: 6861 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 6920
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
+ + K DEG Y +A NS G +T A +TV ++P + E L + +
Sbjct: 6921 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 6980
Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
+ G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+
Sbjct: 6981 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 7038
Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
G Y+ V S S + V + + V L S G + +E + ++
Sbjct: 7039 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 7098
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
+W+ ++I + + ++ G D G+ + +VK+++
Sbjct: 7099 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 7146
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
P F +L T G + +F V G P P I W I S F+ Y ATL
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 6921
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
I + D G + C A N+AG + L V + PL + + V
Sbjct: 6922 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 6972
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
+K + V+ G + E R+ PE ++ W+ G+E+ + S++ +
Sbjct: 6973 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 7023
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ + I + G Y + V +G + + + GEK P V S+
Sbjct: 7024 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 7078
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
G S + + T+ W + ++ + + + + G+T + I K + D+G+Y
Sbjct: 7079 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 7137
Query: 804 TLK-AENSEGIAETSAVI 820
K + + IA+ +A +
Sbjct: 7138 VAKVVKEKKAIAKYAAAL 7155
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
VE E D W R + P N Y+ RK R +V+D G D++
Sbjct: 5857 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 5914
Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
E P+I++ L + G TFE E++ RWFK E+ ++ L
Sbjct: 5915 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 5973
Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
G KQ L I D DDA EY+C NS T N ++ + +P
Sbjct: 5974 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 6028
Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
A + ++IP + + W K IE+ KF++ +D K TL I + +D E
Sbjct: 6029 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 6088
Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
Y V+ ++ T + V V PP+
Sbjct: 6089 YRVVVENSVGSDSGTVNVTVADVPEPPR 6116
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/205 (22%), Positives = 79/205 (38%), Gaps = 14/205 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYC 692
P F++KP Q G D+L+EC L A P+P IAW G + P + + +Y
Sbjct: 5 PRFTQKPSIQQTPTG-DLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-----KTGEKEPPQVIEPLKSMIVR 747
+ L I G Y A N+ GE++ I L + P + + +
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKD 123
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK------ALPTKSDGDTHSITI-LKPKKVKDE 800
G +++ +V P W K+ P+ A+ + T+ + ++ D
Sbjct: 124 GGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDA 183
Query: 801 GVYTLKAENSEGIAETSAVITVEEP 825
G Y N +G + + EEP
Sbjct: 184 GQYRCNIRNDQGETNANLALNFEEP 208
Score = 55.2 bits (127), Expect = 5e-07
Identities = 60/241 (24%), Positives = 95/241 (39%), Gaps = 31/241 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS----QDFQMYYDDDN 564
AP F +K + TP G + EC +E P+P I W +++PS Q
Sbjct: 4 APRFTQKPSIQQTPTGDLLM-ECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLY 62
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
ATLVI+E D G + C A+N G +++ L
Sbjct: 63 KATLVIKEPNAGDGGAYKCTARNQLGESNANINL---------------------NFAGA 101
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
D + P+F KP+ D G+ I++EC++ + P W+ G + + AI
Sbjct: 102 GGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMG-GLYHAI 160
Query: 685 ESDM--HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
SD+ Y L+I G Y N +GE + + L + E +P + E +
Sbjct: 161 FSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFE--EPDPSERQERKR 218
Query: 743 S 743
S
Sbjct: 219 S 219
Score = 54.8 bits (126), Expect = 6e-07
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V
Sbjct: 2939 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 2996
Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E
Sbjct: 2997 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 3056
Query: 816 TSAVITV-EEPTEEN 829
+ I V ++PT N
Sbjct: 3057 ATVKINVIDKPTSPN 3071
Score = 53.6 bits (123), Expect = 1e-06
Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y + A N G+++ + + + E P ++ ++ + + ++ +P P
Sbjct: 5893 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5952
Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A +
Sbjct: 5953 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 6010
Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
I + F+ YE ++G+T+ L+ + +W + ++I I +
Sbjct: 6011 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 6070
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
+ D G + +V++ ++ T+ V +PE
Sbjct: 6071 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 6113
Score = 52.8 bits (121), Expect = 3e-06
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
T A S A + + + ++ PP+ + + T + G++ L + +
Sbjct: 349 TTGASASATSATSGGSASSDASRDKYTRPPIVLEASRSQTGRIGGSVVLEVQWQCHSSTI 408
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++ S +Q+F+G +L + + E SG YKC A G+ A V I
Sbjct: 409 IEWYRDGTLVRNSSEYSQSFNGSIAKLQVNKLTEE-KSGLYKCHAKCDYGEGQSSAMVKI 467
Query: 924 ---DVEK--VTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959
DVE+ + K + Y+ EE K+ L+ +T V+ +
Sbjct: 468 EQSDVEEELMKHRKDAEDEYQKEEQKSQTLQAETKKRVARR 508
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
C L V + +E Y V AVN+ G P +K+K + P +K + ++
Sbjct: 1750 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 1808
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
GE++ + G P P W N KP+KA+ I+K + D G +T+
Sbjct: 1809 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1868
Query: 806 KAENSEGIAETSAVITV 822
+NS G +++A +TV
Sbjct: 1869 TLKNSSGSCDSTATVTV 1885
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P V L + G V FEC++ G PRP+ WF+ + + + + D L+
Sbjct: 5923 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 5981
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
I ++ +DA +TC A N++G S+ L ++
Sbjct: 5982 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 6013
Score = 51.6 bits (118), Expect = 6e-06
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
+ S P+V +G P+++E +++ V + E+ IL+ +V G+P PT W K ++ V +
Sbjct: 965 KTSTPLVPSGASGSA--PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVIS 1022
Query: 778 ---LPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEG 812
+DG H++ + K + +DEG YTL EN G
Sbjct: 1023 GGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHG 1061
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
+I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V
Sbjct: 2346 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 2405
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
V G P P W N KPV + + + + +L+ K G+YTL A N+
Sbjct: 2406 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2465
Query: 812 GIAETSA-VITVEEPT 826
G + S VI + +P+
Sbjct: 2466 GSDKHSVEVIVLGKPS 2481
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
I LP E P V K P F C+ G P P W R +
Sbjct: 5515 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 5574
Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
S ++ + D V I+EV+ DAG +T N G ++T L+V+AP
Sbjct: 5575 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 5625
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V
Sbjct: 2051 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 2110
Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P P + W K N+ ++ L + + H+I + D G Y L +NS
Sbjct: 2111 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 2170
Query: 811 EGIAETSAVITV-EEPTEEN 829
G E A +TV + P++ N
Sbjct: 2171 HGADEEKANLTVLDRPSKPN 2190
Score = 49.6 bits (113), Expect = 2e-05
Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
+TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y
Sbjct: 6855 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 6914
Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
+ Y C A N G+ +T + ++ +P++ + +E
Sbjct: 6915 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 6974
Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
KH G+ A ++G P EV+W +NG +L N + +I+ +T I
Sbjct: 6975 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 7033
Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
S + Y +E + GT+ V V +L V + + P
Sbjct: 7034 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 7067
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
P +L + + G A F ++ + + L+ W +G I S+ + + K L+
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6922
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
I D D G+Y C NS + A LTV ++P +N LR+ + + +
Sbjct: 6923 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 6982
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
V + +V W + + + +K ++ D + + I D Y
Sbjct: 6983 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 7042
Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
+ + S L V + P + G ++++ +W
Sbjct: 7043 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 7102
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
S+ I+K + K + L IK VE D GIY
Sbjct: 7103 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 7137
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
+ SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++
Sbjct: 5479 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 5538
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
+ + + + VG P PT W +N + + SDG + TI +
Sbjct: 5539 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 5597
Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825
+ D G YT++ N G +A + V+ P
Sbjct: 5598 I-DAGEYTVEVSNPYGSDTATANLVVQAP 5625
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/121 (26%), Positives = 48/121 (39%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +KA N G + S + P + + F VK T+ V P P
Sbjct: 3534 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 3593
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
I W+ N +S + + +N + T + DSG YK VA+N +GK H V
Sbjct: 3594 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 3653
Query: 923 I 923
I
Sbjct: 3654 I 3654
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
T V+K Y VVAVN+ G T + E P+ L K V+ GE ++
Sbjct: 4406 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 4465
Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G
Sbjct: 4466 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 4522
Query: 813 IAETSAVITV 822
AE + ITV
Sbjct: 4523 EAEANIKITV 4532
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+
Sbjct: 2036 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 2081
Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
P FI + + ITVK T++ ++ P+P + W++ N+ + +T
Sbjct: 2082 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 2139
Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
D E I + S + D G+Y+ NS G A +T+
Sbjct: 2140 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 2182
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
G + EC + P P+ W FKG +E+V ++ + D VL I ++
Sbjct: 5937 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 5991
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
YT A N G S L+IKT P+V P K ++GE++ L P+
Sbjct: 5992 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 6047
Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
W K+ + ++ +D ++ I + +D G Y + ENS G + +
Sbjct: 6048 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 6106
Query: 821 TVEEPTEENAEPPLF 835
TV + EPP F
Sbjct: 6107 TVADV----PEPPRF 6117
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
+ N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L
Sbjct: 3230 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 3289
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
+ V G P PTITW PV++ + T K+ D G Y +KAEN G
Sbjct: 3290 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 3349
Query: 813 IAETSAVITV 822
+TV
Sbjct: 3350 TDTAEVKVTV 3359
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
K+E + + A NS G E S + E+ P IN ++ITV+ TI++ +
Sbjct: 4804 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 4863
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
NP P I + N I +E D E+VIT S+ D+G YK A+N GK
Sbjct: 4864 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 4921
Query: 916 S 916
+
Sbjct: 4922 T 4922
Score = 45.2 bits (102), Expect = 5e-04
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)
Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S
Sbjct: 2707 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 2761
Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
+ I +K+K+ +P IE R G P K N K +P
Sbjct: 2762 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 2821
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
GDTH T+ K D + +KA NSEG + ET I + P + P
Sbjct: 2822 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 2875
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
+ N+K+ +E + + A N+ G + S P + P++ E L V+ G ++
Sbjct: 2639 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 2698
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
+ G P P +TW N K + + + + + PK + K G YT+ A N G
Sbjct: 2699 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 2758
Query: 813 IAETSAVITVE-EPTE 827
+ I V+ +PT+
Sbjct: 2759 TDSVTINIKVKSKPTK 2774
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
N+K E + V+AVN G + S P +I P+++ + + ++ G + L
Sbjct: 4112 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 4171
Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
+G P PT TW + P D + + +I P K D G Y LK +N G
Sbjct: 4172 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 4231
Query: 815 ETSAVITVEE 824
E + V++
Sbjct: 4232 EAIFEVIVQD 4241
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G
Sbjct: 4794 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 4853
Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
E++ I GNP+P I N P+ + T D + I I K D G Y +
Sbjct: 4854 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 4913
Query: 807 AENSEG 812
A N G
Sbjct: 4914 ATNKYG 4919
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P
Sbjct: 3533 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 3592
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
P+I WF + + + + + DN L + D+G + VA N +G
Sbjct: 3593 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 3644
Score = 41.9 bits (94), Expect = 0.005
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ ++A+N G+ + S + N P + N QEI VK L V+ P P
Sbjct: 3241 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 3299
Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ITW + + S N DG+ V + S D+G Y A N G + +V
Sbjct: 3300 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 3357
Query: 922 TI 923
T+
Sbjct: 3358 TV 3359
Score = 41.5 bits (93), Expect = 0.006
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
KN + +AL D T ++ LK +E + + A N G + S N
Sbjct: 2620 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 2676
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
P + + TVK T+K + + P P +TW N + I S+ +N I
Sbjct: 2677 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 2734
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
SG Y A+N G S VTI+++
Sbjct: 2735 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 2767
Score = 41.1 bits (92), Expect = 0.008
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT
Sbjct: 2987 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 3045
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A NA G +T ++ +++ P S +G
Sbjct: 3046 IKAVNANGEDEATVKINVIDKPTSPNG 3072
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++ + + YP+ + W + I+ + F + DD ATL I ED G +
Sbjct: 6033 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 6091
Query: 584 VAKNAAGFASSTTELIV 600
V +N+ G S T + V
Sbjct: 6092 VVENSVGSDSGTVNVTV 6108
Score = 40.3 bits (90), Expect = 0.015
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP V+E +S R G SV+L Q + I W ++ V+ S SI L+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 794 PKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEE 828
K+ +E G+Y A+ G ++SA++ +E+ E
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDVE 473
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP F LR + + C ++G P P I W + + +D
Sbjct: 6702 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 6759
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V +L I +DAGT+T A N G S L V+
Sbjct: 6760 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 6797
Score = 39.9 bits (89), Expect = 0.019
Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P KP+ + C V PEP WL G E+ E+ E+ +
Sbjct: 5530 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 5587
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
Y +K V G YTV N G + L ++ PP + + + + I+ G+
Sbjct: 5588 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 5641
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
V L G + N + + PT + D H + + V++ G Y
Sbjct: 5642 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 5701
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G A T + V E + PL I+ T T+ VT ++
Sbjct: 5702 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 5756
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+S E +T + +++ ++T + E +++ A N G
Sbjct: 5757 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 5801
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/141 (19%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
++ E+ + I E ++ V P+ + P + + +TV E T L +V+ +P P+
Sbjct: 954 MRRESVQEILEKTSTPLV--PSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTF 1011
Query: 865 TWYRNNEIISPSETITQNFDGE--NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
W++ + + DG+ + L + S+ D G Y N G S ++
Sbjct: 1012 RWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQ-DEGPYTLTIENVHGTDSADVKLL 1070
Query: 923 IDVEKVTFVKHLQKSYETEEG 943
+ + + + K E++ G
Sbjct: 1071 VTSDNGLDFRAMLKHRESQAG 1091
Score = 39.1 bits (87), Expect = 0.034
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T
Sbjct: 2402 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 2458
Query: 583 CVAKNAAGFASSTTELIV 600
A NA+G + E+IV
Sbjct: 2459 LTATNASGSDKHSVEVIV 2476
Score = 39.1 bits (87), Expect = 0.034
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N
Sbjct: 6727 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 6785
Query: 1652 GTSSVEVTLKVYDKPSKP 1669
G E L V K +P
Sbjct: 6786 GVDVSECVLTVQTKGGEP 6803
Score = 38.7 bits (86), Expect = 0.045
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
++ + E ++K P+ S AP VE + T C+V G P P WF
Sbjct: 956 RESVQEILEKTSTPLVPSGASGS-APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWF 1014
Query: 545 RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + + F+ D ++ L + + +D G +T +N G S+ +L+V
Sbjct: 1015 KGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV--- 1071
Query: 604 LSDHG 608
SD+G
Sbjct: 1072 TSDNG 1076
Score = 38.3 bits (85), Expect = 0.059
Identities = 18/96 (18%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
PP ++ ++Q G E++ ++ W++DG+ ++ S+ + +G KL+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1165 IYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSI 1196
+ + +G Y C+ G + +A++ +E+ +
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDV 472
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/126 (26%), Positives = 50/126 (39%), Gaps = 4/126 (3%)
Query: 1255 IRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
IR+ + D + E +L+ ST + PKIV+ + L
Sbjct: 947 IRRSSIDMRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGS 1006
Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCG--HAD 1370
P P W S+ + K D K + +L + K + D G Y L +EN G AD
Sbjct: 1007 PAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSAD 1066
Query: 1371 VEMNVT 1376
V++ VT
Sbjct: 1067 VKLLVT 1072
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
+ +K Q + V A+N+ GE+ S P + P++ + + V+ G+++
Sbjct: 3523 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 3582
Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
V G P P I W N P+ + T D +T + T L K D G Y + A N
Sbjct: 3583 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 3642
Query: 811 EGIAETSAVITV 822
G E + +
Sbjct: 3643 SGKDEHEVDVNI 3654
Score = 37.5 bits (83), Expect = 0.10
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
KS+ D H + KP K V+D E +Y +KA N G + + + A
Sbjct: 1735 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 1794
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P +++ +K TIK ++ P+P W N + + + + + +
Sbjct: 1795 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 1854
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I N DSG + NS+G A VT+
Sbjct: 1855 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 1885
Score = 37.1 bits (82), Expect = 0.14
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT--KEKTSVIRIKELKRSHSSKYTIEAS 1648
++T + G P P W+K ++ + + T KE T + + + + YT+
Sbjct: 998 ILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIE 1057
Query: 1649 NTAGTSSVEVTLKV 1662
N GT S +V L V
Sbjct: 1058 NVHGTDSADVKLLV 1071
Score = 37.1 bits (82), Expect = 0.14
Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y
Sbjct: 6983 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 7041
Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+L + + V V + +K PP + + SS P G ST + +
Sbjct: 7042 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 7088
Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
E++ ++ T +W + ++++KT ++++ V + D + KV+K
Sbjct: 7089 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 7143
Query: 1476 ETK 1478
E K
Sbjct: 7144 EKK 7146
Score = 36.7 bits (81), Expect = 0.18
Identities = 20/91 (21%), Positives = 36/91 (39%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PP +++ R + G V L V +Q EW + +++ S + A L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ K+ +G+YK + + G V I
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKI 467
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+E + + A N G ++ S N +P + + + +T+K +I V+
Sbjct: 2939 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 2998
Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+
Sbjct: 2999 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 3056
Query: 917 HGARVTIDVEKVT 929
++ + ++K T
Sbjct: 3057 ATVKINV-IDKPT 3068
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
L+N + N +LTC G P P + W +DG + + R
Sbjct: 6714 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 6773
Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
Y A ND G + CV+ +Q K
Sbjct: 6774 AGTYTVTATNDLGVDVSECVLTVQTK 6799
Score = 36.3 bits (80), Expect = 0.24
Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 4/104 (3%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY--- 560
E +S P FV K R G+ + EC+V+ P W + + + +
Sbjct: 105 EAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDL 164
Query: 561 -DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
D + L IR DAG + C +N G ++ L E P
Sbjct: 165 GDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFEEP 208
Score = 36.3 bits (80), Expect = 0.24
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++
Sbjct: 2079 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 2138
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
+ + L I D G + KN+ G L +++ P +G
Sbjct: 2139 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 2191
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENI---ELVITNVDSEIDSG 902
G + + + +P P+I W + ++ PS + Q G ++ LVI ++ D G
Sbjct: 19 GDLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAG-DGG 77
Query: 903 DYKCVASNSAGKSS 916
YKC A N G+S+
Sbjct: 78 AYKCTARNQLGESN 91
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PP V W+K+ +L+ +Y + I +K +YT+ A N+ GT V L
Sbjct: 6613 PPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 6672
Query: 1661 KV--YDKPSKPE 1670
V + +P K E
Sbjct: 6673 NVTRHSEPLKFE 6684
Score = 35.5 bits (78), Expect = 0.42
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVK 845
H +T L PKK + V A + S IT + PT + ++I
Sbjct: 5091 HRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLT---RDILAY 5147
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDY 904
K++ +P P +T+ + ISP++ + + + +T SE+ D G Y
Sbjct: 5148 AGERAKILVPFAASPAPKVTFSKGENKISPTDPRVK-VEYSDFLATLTIEKSELTDGGLY 5206
Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
NS G S R+ + V+K +H++
Sbjct: 5207 FVELENSQGSDSASIRLKV-VDKPASPQHIR 5236
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++++ + G P P+ W +K +M + + I D+G FT
Sbjct: 1810 GETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMS-SERGKHIMKIENAVRADSGKFTI 1868
Query: 584 VAKNAAGFASST-TELIVEAPLSDHG 608
KN++G ST T +V P G
Sbjct: 1869 TLKNSSGSCDSTATVTVVGRPTPPKG 1894
Score = 34.7 bits (76), Expect = 0.73
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 499 EKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDF 556
++ ++ +++AP I E L G+T++F ++G P P +TW F I +
Sbjct: 2668 DRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQI 2727
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
+ ++ ++ + + + +G +T A N G S T + V++
Sbjct: 2728 E---NEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKS 2770
Score = 33.5 bits (73), Expect = 1.7
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G V G P P ITW F T + S D ++D ++ D GT+
Sbjct: 3284 GQDFSLNIPVSGEPTPTITWTFEGTPV--ESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3341
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A+N G ++ ++ +++ P S G
Sbjct: 3342 IKAENENGTDTAEVKVTVLDHPSSPRG 3368
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/97 (21%), Positives = 34/97 (35%), Gaps = 2/97 (2%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P + P+ V E +L C++ P P W E++ + H
Sbjct: 977 GSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHT 1036
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
L + + EG YT+ N G S + L +
Sbjct: 1037 V--ALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 1071
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+PP + + V G D L + P P I W F+G + D+ + + E
Sbjct: 3267 VPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTK 3326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
+ + + GTY + A N G + + + + P
Sbjct: 3327 F----HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSP 3366
Score = 31.9 bits (69), Expect = 5.2
Identities = 12/42 (28%), Positives = 22/42 (52%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
+P + + +N+T NE LTC G P P W++ +++
Sbjct: 979 APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREV 1020
Score = 31.5 bits (68), Expect = 6.8
Identities = 34/179 (18%), Positives = 68/179 (37%), Gaps = 15/179 (8%)
Query: 752 VILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGDTHSIT-ILKPKKVKDEGVY 803
+++ + +P+PTI W + + V+ L T G + T ++K D G Y
Sbjct: 21 LLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTL-TPLGGSLYKATLVIKEPNAGDGGAY 79
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPV 861
A N G + + + + A+ P F+ + + I I + +V
Sbjct: 80 KCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSAST 139
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVD----SEIDSGDYKCVASNSAGKSS 916
P W ++ +S F + + ++ S D+G Y+C N G+++
Sbjct: 140 PVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETN 198
>Z73897-4|CAA98064.2| 6839|Caenorhabditis elegans Hypothetical protein
ZK617.1a protein.
Length = 6839
Score = 318 bits (782), Expect = 2e-86
Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)
Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
+K+ + + K +C S +WY ++KEI SG +I+ E
Sbjct: 816 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 875
Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
D G C T L V E + F+ L + E+ A+L ++N+ A +VW
Sbjct: 876 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 935
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
R + I+ ++ EK R L I+ D+ E++ I +D +V V E
Sbjct: 936 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 995
Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
+ +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I
Sbjct: 996 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 1055
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
++D GEY C + + A L V+ + F + L + ++ + D L + D
Sbjct: 1056 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 1113
Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
W++ I KF S TL I K ++ Y + + + V
Sbjct: 1114 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 1173
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
E P + ++ K G + V +Q P + + N K I + K + I
Sbjct: 1174 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 1233
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
A + K + D G + L L N+ G A + + DKP PP P + + +
Sbjct: 1234 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 1293
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N
Sbjct: 1294 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 1353
Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
E +SD E+ Y K + + V+K + EP E+ I G +
Sbjct: 1354 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 1413
Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
+ + W++ G+ T K E++ C DHG+
Sbjct: 1414 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 1466
Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
+ +K + IK + KVG+ I G P PE +W NG L+ +
Sbjct: 1467 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 1525
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
+++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ +
Sbjct: 1526 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 1585
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR
Sbjct: 1586 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 1645
Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
V A N G SE L ++ IK D P D + + I W P K+GG+PI
Sbjct: 1646 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 1704
Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
+Y VE++ + K+WK A I L YQFR+ A N+ G P +K
Sbjct: 1705 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 1764
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
P + + S + T++W GG PI E K KG +
Sbjct: 1765 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 1818
Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
+T+ +EH CI + D +R++ +N+ G + +V L++ PS P P
Sbjct: 1819 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 1873
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L
Sbjct: 1874 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 1931
Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+ TY R+ A N+ G S+ L +D+ K
Sbjct: 1932 KGQTYQFRVKAVNKEGASDALSTDKDTK 1959
Score = 253 bits (619), Expect = 1e-66
Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)
Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
P ++D +E ++K G D +L + P P W ++ K + +
Sbjct: 2949 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 3008
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
+K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP
Sbjct: 3009 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 3068
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD
Sbjct: 3069 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 3128
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
E E + K+ ++ P + + D++ T GG P V
Sbjct: 3129 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3187
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
A ++ A N GE + S + + + + N
Sbjct: 3188 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3247
Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K
Sbjct: 3248 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3307
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG
Sbjct: 3308 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 3367
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L
Sbjct: 3368 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 3424
Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
S+ IV K D P D + V + W P +GG+PI Y VE K + W
Sbjct: 3425 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 3483
Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
A L+ TYQFR+ A N+ G P + P
Sbjct: 3484 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 3543
Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ +K +P+ + T+ + + S H ++
Sbjct: 3544 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 3603
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
D +++I EN G + +V VP P PL+I + +W P
Sbjct: 3604 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 3657
Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
+GG +L Y + D ++ W EVG T K N L Y R+ A N G S+
Sbjct: 3658 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 3715
Query: 2052 PLESDEP 2058
PLE++EP
Sbjct: 3716 PLEAEEP 3722
Score = 251 bits (614), Expect = 5e-66
Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
PKI+ R+ +IK G L VD+ P P W V S + S+
Sbjct: 3831 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 3890
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
+ D+G YKL+++N G + V + D+PS P P + ++ S + W P++
Sbjct: 3891 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 3950
Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+
Sbjct: 3951 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 4010
Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
T E V+ + +P KP + I N+ I++ GG P R D
Sbjct: 4011 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 4066
Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
K + K Y+ +A N G + S + + P
Sbjct: 4067 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 4126
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
+ + + + K G+ ++T P P++ W K G K E TT +T ++
Sbjct: 4127 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 4182
Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
I +RS S I+A N G + + + V DKP PE + +SR + T+ W P
Sbjct: 4183 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 4241
Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+
Sbjct: 4242 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 4300
Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
+ P+VIK D P D V + W P +GGSPI+ Y VE K+
Sbjct: 4301 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 4359
Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
G W + L N TYQFR+ A N G P + +T + P
Sbjct: 4360 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 4419
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
P V + T S L W P +GG+PI YI+E K + WT+ +
Sbjct: 4420 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 4479
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
+N+ EK+E FR+ A N+ G P++ S V +E+ P
Sbjct: 4480 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 4519
Score = 250 bits (612), Expect = 8e-66
Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y
Sbjct: 2080 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 2138
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
L N G + V +L KPS P G + + ++ W PE+ G + I +Y +
Sbjct: 2139 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 2198
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ +
Sbjct: 2199 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 2256
Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
+ P V+KP + + D+ GG P + K + + A ++
Sbjct: 2257 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 2316
Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
++ A N G + S VV + I ED+ KVG
Sbjct: 2317 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 2376
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
I+G P P+V W NG + K I + S + + R S KYTI A+
Sbjct: 2377 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 2435
Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK
Sbjct: 2436 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 2495
Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
+ W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D
Sbjct: 2496 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 2552
Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
P D++ V + W P +GG+PI +Y++E + + +W+ A
Sbjct: 2553 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 2611
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
+ L+ N Y+FR+ A N+ G S P + + P R+ + + + ++
Sbjct: 2612 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 2671
Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
+ P S +P +T + + + ++ K+ + ++ ++ D F I A
Sbjct: 2672 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 2730
Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I
Sbjct: 2731 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 2785
Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
D W+ KV + + L H Y R+ A N G S+PLE+
Sbjct: 2786 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 2837
Score = 243 bits (595), Expect = 1e-63
Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
R+K G + V+ + P P EW +N + +T ++ + LT K D+G
Sbjct: 3255 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 3314
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y
Sbjct: 3315 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 3374
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
VVE QE D W+ + T + L Y+FR AVN S + T + ++
Sbjct: 3375 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 3431
Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
+ P + + + + D+E GG P + +D G ++ A+
Sbjct: 3432 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 3491
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
+ ++ A N G + S G + KP ++ +
Sbjct: 3492 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 3550
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
K G + EG P P W N ++ ++T +S I I R + Y
Sbjct: 3551 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 3610
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E
Sbjct: 3611 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 3670
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K
Sbjct: 3671 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 3728
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
DVP D + + I W P+ NGG+P+ Y VE K++G W
Sbjct: 3729 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 3787
Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
L Y+FR+ A N G S P +D +IT + L P + R + +
Sbjct: 3788 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 3847
Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
++ + + P + + + + +V S + K D ++
Sbjct: 3848 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 3902
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
+ +N +G E +++ PS P PLE+ V + + +W P+ DGGA +
Sbjct: 3903 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 3957
Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP
Sbjct: 3958 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 4015
Score = 242 bits (593), Expect = 2e-63
Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+K G+ + +V P P+ W N K I + K + + + + K +G Y
Sbjct: 2372 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 2430
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+ N G V +N+ + KP+ P P + ++ + W PE+ G I +Y +
Sbjct: 2431 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 2490
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E W+ T ++ +L Y+FR AVN SD ET ++ +
Sbjct: 2491 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 2548
Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
P ++P + T+ + D ++L GG P + + K + + A
Sbjct: 2549 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 2606
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
+ ++ +A N G + S V+ + I + +K K
Sbjct: 2607 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 2666
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + G P P V W+ N+ + N + E S + +K+++R S +T
Sbjct: 2667 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 2726
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE
Sbjct: 2727 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 2786
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K
Sbjct: 2787 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 2846
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
D P D + V + W P +GG+PI +Y VE+K E W
Sbjct: 2847 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 2905
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A + L + Y+FRI A+N+ G P S + + + PP RN +
Sbjct: 2906 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 2964
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
P S +P + E V+ K+ G H ++ D + I
Sbjct: 2965 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 3023
Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
AEN G T V + H PS P PL++ + + +W PE DGGA +
Sbjct: 3024 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 3078
Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E
Sbjct: 3079 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 3133
Score = 235 bits (575), Expect = 3e-61
Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)
Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
+ RIK G+ + L + ++ P P +W N I + S+++ I D
Sbjct: 3547 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 3606
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++
Sbjct: 3607 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 3666
Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
Y+VE + W V + L Y FR AVN S E E
Sbjct: 3667 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 3726
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
+ + P V+KP + DI+ T GG P VT Y KK K + E
Sbjct: 3727 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 3782
Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
++ IA N G + S Q KP I ++ IK
Sbjct: 3783 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 3842
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
K V + G P P W + E + K T+ I KR+ S
Sbjct: 3843 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 3900
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y
Sbjct: 3901 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 3960
Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
+EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K
Sbjct: 3961 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 4019
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
P DN+ + I W P NGGSP+ Y +E K + G+ K
Sbjct: 4020 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 4078
Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
A R+QK TY++R+ A N+ G P S T P +
Sbjct: 4079 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 4135
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
F V +T+ +T SP + I + GK + T S + I +
Sbjct: 4136 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 4186
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
+ D +I A N G + ++++ TV P AP I V + +W
Sbjct: 4187 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 4238
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G
Sbjct: 4239 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 4297
Query: 2049 LSE 2051
LS+
Sbjct: 4298 LSD 4300
Score = 234 bits (572), Expect = 6e-61
Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + +K G+ V V P P +W N ++ + T + ++ L I
Sbjct: 1777 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 1836
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
+D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G
Sbjct: 1837 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 1896
Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T
Sbjct: 1897 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 1955
Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
K+TK ++P ++P K T + + D + + P+ +T Y KK K
Sbjct: 1956 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 2009
Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
+ E ++ ++ A N G E S VV +
Sbjct: 2010 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 2069
Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++
Sbjct: 2070 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 2128
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD
Sbjct: 2129 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 2188
Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
GG + Y IEK + RW+ + T + L EY FRV A N G S+ L
Sbjct: 2189 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 2246
Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
+ I+ K +VP D + V + W + +GG+PI + +E K + +
Sbjct: 2247 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 2304
Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
W+ A + L YQFRI ARN+ GT P D++ P R
Sbjct: 2305 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 2364
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+ + TLK+ +P + K + G+S +I + +
Sbjct: 2365 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 2422
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
K + I+A N G T+S ++ + K + P+ P P+E+ V + W P
Sbjct: 2423 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 2477
Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S
Sbjct: 2478 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 2535
Query: 2051 EPLESD 2056
+PLE++
Sbjct: 2536 DPLETE 2541
Score = 223 bits (545), Expect = 1e-57
Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + IK G ++ V P P W +++ I+ K + L +K++
Sbjct: 2658 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 2717
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G
Sbjct: 2718 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 2777
Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
I YV+E + + W+ + KT + L Y+FR V V+ S+
Sbjct: 2778 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 2834
Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
E + T + +KP K IT + ++L GG P + V +D
Sbjct: 2835 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 2890
Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
+ ++ A N G S V + P
Sbjct: 2891 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 2950
Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
+ N + K K G ++ + + G P P + W G +E+D + ++ + +
Sbjct: 2951 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 3010
Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D
Sbjct: 3011 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 3070
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+
Sbjct: 3071 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 3128
Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
LE+ E I+ K D + D + + W P +GG+PI Y VE++
Sbjct: 3129 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 3187
Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
W A + L TYQFR+ A N+ G S P + P
Sbjct: 3188 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 3247
Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
R+ V++ TL + +P + + + T I + + ++
Sbjct: 3248 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 3307
Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
D ++I A N G + V + +P P PL + + V+ W
Sbjct: 3308 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 3362
Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G
Sbjct: 3363 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 3419
Query: 2050 SEPLESD 2056
S PL SD
Sbjct: 3420 SAPLTSD 3426
Score = 209 bits (510), Expect = 2e-53
Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)
Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
++ ++ G + + + Y P+P + + I + + T ++ +T + +
Sbjct: 4527 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 4586
Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I
Sbjct: 4587 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 4646
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET +
Sbjct: 4647 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 4703
Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
++ + +P +P T+E ++ T GG P Q V R+ + KA
Sbjct: 4704 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 4763
Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
+ N Y + A+N G+ E S + P N + +
Sbjct: 4764 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 4823
Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
+ G+ + P P+V + K NK+ D + + + + I++ + +
Sbjct: 4824 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 4883
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T
Sbjct: 4884 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 4942
Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++
Sbjct: 4943 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 5001
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
+V K +VP+ D+ + W P ++GGS II Y+V+ + +W
Sbjct: 5002 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 5059
Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
AR+ L N ++FRI A+N G S P ++ + PP P +
Sbjct: 5060 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 5119
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
T+ W P +GGS IT Y +E + WT E ++ ++E
Sbjct: 5120 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 5179
Query: 1934 DEIIFRISAENTVGVSLPT 1952
++ FR+ A N G +P+
Sbjct: 5180 NDYEFRVVAINAAGKGIPS 5198
Score = 199 bits (485), Expect = 2e-50
Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
+D + +L + + N ++++ NN G ++ + I D +P PG+P I +
Sbjct: 1624 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 1683
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F
Sbjct: 1684 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 1743
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
R AVN+ SE +E ++ K I + LK+IT + + GG P P
Sbjct: 1744 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 1802
Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
+V W++ ++L+ + T + R Y+ N HG E +
Sbjct: 1803 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 1862
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
+ +P + N ++ D ++ E I Y KL+ + K
Sbjct: 1863 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 1920
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
K + I LK+ + ++ ++A N G S T K YD+P K P ++ +
Sbjct: 1921 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 1979
Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
+ V++EW+PP DGG +T+Y IEK W + V D I L E EY F
Sbjct: 1980 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 2039
Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
RV A N G EA + S +V K P ID E++ + K G
Sbjct: 2040 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 2086
Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
D V + KK W RI+ T + R R G T+ +
Sbjct: 2087 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2146
Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
DK ++ L PS P VS L+W PE +GG+PI +Y IE +
Sbjct: 2147 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 2206
Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
W V G S + + N++ E FR+ A N G S P + + L K+ VP
Sbjct: 2207 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 2263
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
P E+ + V +W P+ DGGAP+ + I +D W E V + +
Sbjct: 2264 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 2320
Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+L E Y RI ARN+ G +P + +
Sbjct: 2321 PNLKEGEEYQFRISARNKAGTGDPSDPSD 2349
Score = 191 bits (465), Expect = 5e-48
Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)
Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
W + ++D +K + S+ K ++R T YT +A + K VEV+
Sbjct: 2102 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 2160
Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
P ++ Y + +D+ V P D + + + + P S++
Sbjct: 2161 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 2217
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
T+ ++ +++R N G +D + N IL K P KP +++ D +
Sbjct: 2218 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 2277
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A
Sbjct: 2278 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 2335
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT
Sbjct: 2336 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 2393
Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
W +GK + +KA EN Y A N +G + + ++ KP
Sbjct: 2394 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 2453
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
K +V D + A ++ PP + + +Y+ D + +
Sbjct: 2454 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 2507
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
+ + L + K+ ++A N+ G S ++ K +D+P +P P +
Sbjct: 2508 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 2566
Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
+ V ++W PPL DGG + +Y IEK RW V T + L N EY FR
Sbjct: 2567 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 2625
Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
V+A N G S+ ++ VI ++ I++ +P +
Sbjct: 2626 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 2685
Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
+ +E G + K ++++ + F I A N G + KI
Sbjct: 2686 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 2742
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
+ T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W
Sbjct: 2743 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 2799
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
V G ++ + E FR++A N G S P E+ L K P AP EI
Sbjct: 2800 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 2858
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ V W P DGGAP+ Y + ++D W +V V + +L E
Sbjct: 2859 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 2918
Query: 2036 TYMIRIYARNEIGLSEPLES 2055
Y RI A+N+ GL +P +S
Sbjct: 2919 KYEFRIRAKNKAGLGDPSDS 2938
Score = 190 bits (463), Expect = 9e-48
Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI
Sbjct: 4267 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 4325
Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N
Sbjct: 4326 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 4385
Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+Y+FR AVN + S +E V K +P V K KN + E + L
Sbjct: 4386 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 4444
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
GG P + + KKL T N ++ IA N GE
Sbjct: 4445 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 4500
Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
E S +V I++ +P+ I+N +DI + G+ + G P +I NGN
Sbjct: 4501 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 4558
Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
EN++ + VI KRS + Y I A+N G + ++ + V D P KP
Sbjct: 4559 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 4617
Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++
Sbjct: 4618 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 4674
Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
L+ N Y FRV A+N G E LE+ + IV K D P E++ + W
Sbjct: 4675 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 4733
Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
+GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N
Sbjct: 4734 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 4793
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
G + IT T P + + + K P + +P +
Sbjct: 4794 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 4853
Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ V + IE + D ++ + EN+ G ++S S+RL+
Sbjct: 4854 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 4905
Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
V P +P IR+ + + W P DGG+P+ Y + D+ + W +V
Sbjct: 4906 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 4964
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
V L + + L +++ Y R+ A + G+SEP E
Sbjct: 4965 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 4998
Score = 183 bits (445), Expect = 1e-45
Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I
Sbjct: 3982 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 4041
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
+I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A
Sbjct: 4042 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 4101
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
VN+ S+++ + ++P + L K + E + +T F PQP +
Sbjct: 4102 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 4159
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
+W ++G K T +++ K A N +GE E + + + KP
Sbjct: 4160 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 4219
Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
+ +H W G E+ YK + + ++ + +
Sbjct: 4220 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 4276
Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
++ L+ ++ I A N G S V V +K +D P P P I + + V++
Sbjct: 4277 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 4335
Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A
Sbjct: 4336 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 4394
Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
N G E SEP+ + ++ P N S +TW ++GG+PI Y
Sbjct: 4395 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 4453
Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
VE K+ G W ++ L Y+FR+ A N G P D + I
Sbjct: 4454 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 4513
Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
+ P N + + T++ P + G PI + + T +V V
Sbjct: 4514 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 4572
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
K D ++ISA N G + V P PT P+ +
Sbjct: 4573 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 4627
Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y
Sbjct: 4628 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 4684
Query: 2040 RIYARNEIGLSEPLESDE 2057
R+ A N+ G+ EPLE+D+
Sbjct: 4685 RVRAENQYGVGEPLETDD 4702
Score = 178 bits (434), Expect = 3e-44
Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D P P KP + + D I+I W+ N G + + Y+VE +E + W T
Sbjct: 3730 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 3789
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S NLK Y FR AVN SD S+ T+ I + + P + + I +
Sbjct: 3790 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 3847
Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
L F G P P TW D + + + YK N
Sbjct: 3848 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 3907
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ GE E V +Q +P + +V D + V+ PP + + N +
Sbjct: 3908 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 3961
Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
++ T S I + +L H ++ + A NT G S S+ V K
Sbjct: 3962 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 4021
Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV
Sbjct: 4022 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 4080
Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
+ ++ + Y +RV+A N G + +S K + P
Sbjct: 4081 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 4140
Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
E + IT P SP D + +EG K + I + +
Sbjct: 4141 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 4194
Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
+I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I
Sbjct: 4195 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 4248
Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S +
Sbjct: 4249 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 4306
Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
V ++ P P+ P EI +N V +W P DGG+P+LGY + W
Sbjct: 4307 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 4365
Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
V V + + L EN TY R+ A N G EP EP P
Sbjct: 4366 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 4413
Score = 176 bits (428), Expect = 2e-43
Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+I+ + ++ +A F E + + RW ++G E+ S+ + K I
Sbjct: 5214 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 5273
Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
+ DAGEY+ EV G+ TA L V+ P + +P IL + Y +
Sbjct: 5274 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 5332
Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
P V ++ + T + D T+ E + EYT ++TT
Sbjct: 5333 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 5392
Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ V P + I T + ++ P + + S +++K +K
Sbjct: 5393 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 5446
Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
+ + + +K + G+ Y+ R+ EN G V + I P PP P
Sbjct: 5447 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 5506
Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
I+++ + + W P + G + Y+VE QE + EW + + NL
Sbjct: 5507 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 5566
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
YR+R +AVN+ +SD +E + + + P + PL ++ E + C
Sbjct: 5567 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 5625
Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
G P+P+ W++ K+L T+K T N+ Y C A N G
Sbjct: 5626 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 5685
Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
T + I+ KP + I + + + G+ + + P E W K+G K+EN+ +
Sbjct: 5686 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 5745
Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I
Sbjct: 5746 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 5804
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y
Sbjct: 5805 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 5861
Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
FR+IA+N G S+ E + P++I
Sbjct: 5862 EFRIIAENKHGQSKPCEPTAPVLI 5885
Score = 171 bits (416), Expect = 5e-42
Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)
Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+++R N GH + VT ++KP P P + +I +S + W+ P G +
Sbjct: 4389 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 4448
Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++
Sbjct: 4449 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 4508
Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
V+ E + P + LK+IT E I++ + GG P+P + + + +
Sbjct: 4509 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 4566
Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
T YK A N +G+ V+ KP I DI
Sbjct: 4567 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 4626
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
Q + W G + I K ++ + +R++ L +
Sbjct: 4627 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 4681
Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
++ + A N G T V +D P P P + E S E++T++W P DG
Sbjct: 4682 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 4740
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
G + Y IEK E + W K A + + + L Y FRV A N G E ++
Sbjct: 4741 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 4800
Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
S PI A P + +P + + +I
Sbjct: 4801 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 4860
Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
+ K I+K + + + N G SD K + P+ P+
Sbjct: 4861 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 4914
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
+ V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + +
Sbjct: 4915 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 4973
Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
+ + + FR+ AE GVS P E V + K+ VP+ P AP +R S W
Sbjct: 4974 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 5032
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N
Sbjct: 5033 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 5090
Query: 2047 IGLSEPLESDE 2057
G S+P E
Sbjct: 5091 AGFSKPSPPSE 5101
Score = 163 bits (396), Expect = 1e-39
Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++
Sbjct: 1328 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 1385
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
+D + W+ PE G + I Y++E +E +W V + + K + Y
Sbjct: 1386 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 1445
Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
+R AVN+ D + + K+ K K +K++ + E I+ G P
Sbjct: 1446 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 1504
Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
P+ W +GK LK ++ + + N G +++ V
Sbjct: 1505 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 1564
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
+ +P DI G + P + ++N +Y K
Sbjct: 1565 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 1624
Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I +
Sbjct: 1625 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 1683
Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
+ + I W+PP DGG + +Y +E +PD W +V V D I L E EY
Sbjct: 1684 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 1741
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
FRV A N G + E + +P+ + W K GG
Sbjct: 1742 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 1799
Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
PI + K +++ + I + ++R+ +N G
Sbjct: 1800 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 1855
Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+
Sbjct: 1856 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 1913
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
W V + H I+ +K+ FR+ A N G S + K+ T
Sbjct: 1914 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 1970
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
++ ++ V W P+ DGGAP+ Y I + W E GKV + I
Sbjct: 1971 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 2030
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
L E Y R+ A N+ G E SD KV+
Sbjct: 2031 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 2060
Score = 142 bits (343), Expect = 3e-33
Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
P PP I + I W P G S I Y VE +E +T W S N+ + +
Sbjct: 5112 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 5171
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
++ L+ + Y FR A+N S + K+ + + V KP T +P N
Sbjct: 5172 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 5229
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
TC G P+P W R+G++L ++++ +E Y
Sbjct: 5230 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 5289
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
N +G + + +Q PVI +D+ GD + G P N +
Sbjct: 5290 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 5346
Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
++ D I + +I I L + +Y SN +G ++ L V P P+G
Sbjct: 5347 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 5406
Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L
Sbjct: 5407 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 5465
Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
EN EY FRV AQN G L SE PI+ + D P + + V ++W
Sbjct: 5466 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 5524
Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
+GG + Y VE ++E +W + L Y++R++A N+ G
Sbjct: 5525 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 5584
Query: 1848 S 1848
S
Sbjct: 5585 S 5585
Score = 132 bits (320), Expect = 2e-30
Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)
Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
K T KL V V++ P K R I+ + + + ++ P+ N + + +++K
Sbjct: 4601 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 4656
Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
+ T +V N DA +++R EN G + +E + I+ D P P
Sbjct: 4657 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 4716
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ +
Sbjct: 4717 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 4776
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
L +Y FR A N + S + + + P + + ++I E +
Sbjct: 4777 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 4834
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
+ F P PKVT+ + K+ K Y + Y N
Sbjct: 4835 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 4894
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
G S + + KP S + I+ + D W+ + G P I K
Sbjct: 4895 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 4951
Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
+ + K +++ + + L + + ++ + A G S V V ++
Sbjct: 4952 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 5011
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D +
Sbjct: 5012 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 5068
Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
+ + L +N E+ FR+IA+N GFS+ + SE +K+ P I
Sbjct: 5069 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 5127
Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
ITW ++GGS I Y VEI++ G W + KL Y+FR+
Sbjct: 5128 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 5187
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A N G +P I I + + S+P+ V E T++
Sbjct: 5188 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 5225
Score = 129 bits (311), Expect = 2e-29
Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ +
Sbjct: 4997 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 5055
Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
WI+ K Q + L+ N + FR A N S S +E ++ P
Sbjct: 5056 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 5115
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
+ K+I + + G K+T Y R+ G L T + Y R
Sbjct: 5116 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 5173
Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
++ +A N G+ S G IQ+ +P I + ED Q + +
Sbjct: 5174 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 5233
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
AV G P P W +NG +L Y + IKE+ + +YT+E SN
Sbjct: 5234 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 5291
Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
G+ + L V P PVI +++ TI L G L K P
Sbjct: 5292 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 5337
Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
+ + ++D D T I + +++ ++ G E S T L+V
Sbjct: 5338 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 5397
Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
P I + ++W P +GGS I Y VE + K +W
Sbjct: 5398 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 5457
Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
I L N Y+FR+ A+NE G P S+ I PP+ P N + +
Sbjct: 5458 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 5517
Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
VTL W P S+GG + YI+E + + W + + + + N+ + + +R+
Sbjct: 5518 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 5577
Query: 1942 AENTVGVS 1949
A N G+S
Sbjct: 5578 AVNDAGLS 5585
Score = 124 bits (299), Expect = 7e-28
Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)
Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
W P +GGSPI +Y K++++ KW K + L + Y+FR+ A
Sbjct: 4930 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 4989
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
+ G S P D + P+QP V + S L+W +P +GGS I Y ++
Sbjct: 4990 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 5048
Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
++ W + + E C + +++ E FRI A+N G S P+ S+ +L
Sbjct: 5049 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 5105
Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
+ P PP + + +G N +W P DGG+ + GYN+ IR+ T+W
Sbjct: 5106 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 5164
Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
+V +F + L E + Y R+ A N G P P K+ GS
Sbjct: 5165 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5212
Score = 99 bits (238), Expect = 2e-20
Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)
Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P I WY++ + I + +N+ +I N D+G Y C A+ G +H
Sbjct: 836 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 892
Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
++ K +F+ L + E K +L C+ + WY K I D R II+
Sbjct: 893 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 952
Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
+ GR I +D + + V+E F+ ++ +V E D+A
Sbjct: 953 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 1012
Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+
Sbjct: 1013 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 1072
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
A++ +V+ + I L++ +V + + T + WF++G +I
Sbjct: 1073 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 1131
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+ LKI ++++A Y + + + +TV E
Sbjct: 1132 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 1172
Score = 99.1 bits (236), Expect = 3e-20
Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)
Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ +
Sbjct: 1276 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 1333
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
++++KE E FR+ A N G+S P +SV + VP P ++ V +
Sbjct: 1334 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 1392
Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
+W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A
Sbjct: 1393 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 1452
Query: 2045 NEIGLSEPLESDEPFKV 2061
N+ G +P + +P K+
Sbjct: 1453 NKAGPGDPCDHGKPIKM 1469
Score = 98.3 bits (234), Expect = 5e-20
Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
+S + TL W P ++GGS IT+Y++E + + W VTV +V + + + +
Sbjct: 5410 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 5466
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW
Sbjct: 5467 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 5523
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P DGG L GY + ++ W + +N+ +L + Y R++A N+ G
Sbjct: 5524 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 5583
Query: 2049 LSEPLESDEPFKVIPGEG 2066
LS+ E D+ G G
Sbjct: 5584 LSDLAELDQTLFQASGSG 5601
Score = 94.3 bits (224), Expect = 9e-19
Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)
Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
L D+ +T+ K + L +H ++ + A N G S + ++ +D P
Sbjct: 5443 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 5502
Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
+ P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y
Sbjct: 5503 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 5561
Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
+ L + +Y +RV A N G S+ E + + + A ++ E
Sbjct: 5562 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 5620
Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
F E + GSP +Y+ + + K+ I L+ + ++ A
Sbjct: 5621 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 5679
Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
N GT + T + PP + + T++ P +
Sbjct: 5680 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 5735
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + ++ S I T I N +D +R+ EN+VG T + +V
Sbjct: 5736 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 5789
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K
Sbjct: 5790 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 5848
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
I L Y RI A N+ G S+P E P +IPG+
Sbjct: 5849 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 5888
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
T LDVP I E + W P NGG+ ++ Y VE + W+
Sbjct: 3627 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 3686
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A++ KL Y FR+ A N G S P +++ I P V++
Sbjct: 3687 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 3746
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
+ +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+
Sbjct: 3747 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 3804
Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
A N G S P++ ++ K + P TA +I++ N+ + G P+
Sbjct: 3805 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 3859
Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
P + + + V K ++ F +++ Y +++ +NE+G E
Sbjct: 3860 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 3912
Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
+ F+VI + A E P E ++V
Sbjct: 3913 EAIFEVIVQDRPSAPEGPLEVSDV 3936
Score = 88.6 bits (210), Expect = 4e-17
Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ +
Sbjct: 6263 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 6321
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
+TI + K D+G YT++A+NS G E + V +E PL E K
Sbjct: 6322 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 6374
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
++ R P T++ N +I + +T + G + D D
Sbjct: 6375 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 6434
Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
V+ S S +D + T+ + + V+ TV TK
Sbjct: 6435 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 6486
Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
+S R + + G +I+ + D + + L K T +P F
Sbjct: 6487 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 6546
Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
+L D E + A ++ + ++ W +GE I +++ L I +
Sbjct: 6547 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 6606
Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
DEG+Y C + E A +TV VE + L + VN
Sbjct: 6607 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 6666
Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV
Sbjct: 6667 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 6726
Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
+ +++ V E + RLP + P T+E + E L V W++
Sbjct: 6727 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 6786
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
IE E+ + L I+ +DD Y ++ K
Sbjct: 6787 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 6826
Score = 87.8 bits (208), Expect = 7e-17
Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S
Sbjct: 5627 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 5686
Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
L++ KP P +++ TIE K P ++ + + +NN
Sbjct: 5687 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5746
Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
+ D+ T I + +RV+ +N VG V T DVP
Sbjct: 5747 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 5800
Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
+D E+V ++W P +GGS + +Y +E ++ G W I+ L
Sbjct: 5801 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 5859
Query: 1834 TYQFRIYARNEIGTSLP 1850
Y+FRI A N+ G S P
Sbjct: 5860 QYEFRIIAENKHGQSKP 5876
Score = 70.5 bits (165), Expect = 1e-11
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
+P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V +
Sbjct: 5400 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 5458
Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
+ + L ENH Y R+ A+NE G+ PL S+ P
Sbjct: 5459 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 5492
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP
Sbjct: 5574 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5633
Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
W CK + GD + I+ D YT +A NS G T A +
Sbjct: 5634 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 5692
Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
++ +P +FI ++ +KG TI+L P W ++ E I +
Sbjct: 5693 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 5746
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ D + L I+N E D G+Y+ V NS G S VT+
Sbjct: 5747 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 5789
Score = 66.9 bits (156), Expect = 1e-10
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ K +G + F C+V P +TW + +K S + Y+ ++ L
Sbjct: 6266 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 6324
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I V +D G +T AKN+ G T E IV ++ H + +
Sbjct: 6325 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 6380
Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
E P F+ + + + + L C L P P I W+ G V ++ + V+
Sbjct: 6381 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 6439
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
S + CS L+I N + GTYTV A N G VL ++T EP P+V
Sbjct: 6440 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 6488
Score = 66.5 bits (155), Expect = 2e-10
Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P+F+ + + G + PEP I WL GE I ++ + +
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 6600
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
L+I++ KK EG Y A N G+ L +K + + +V + L
Sbjct: 6601 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 6660
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
IV GESV A+V G P + W +N + + DG+T S TI D
Sbjct: 6661 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 6718
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
G Y L+ S+G S V E A+PP + R ++ G+
Sbjct: 6719 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 6773
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
++ W+R +E I +E + G +L I NV+ + D G Y
Sbjct: 6774 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 6818
Score = 62.9 bits (146), Expect = 2e-09
Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
E P L G S SA V G P P I W N + + ++ T
Sbjct: 6542 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 6601
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
+ + K DEG Y +A NS G +T A +TV ++P + E L + +
Sbjct: 6602 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 6661
Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
+ G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+
Sbjct: 6662 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 6719
Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
G Y+ V S S + V + + V L S G + +E + ++
Sbjct: 6720 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 6779
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
+W+ ++I + + ++ G D G+ + +VK+++
Sbjct: 6780 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 6827
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
P F +L T G + +F V G P P I W I S F+ Y ATL
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 6602
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
I + D G + C A N+AG + L V + PL + + V
Sbjct: 6603 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 6653
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
+K + V+ G + E R+ PE ++ W+ G+E+ + S++ +
Sbjct: 6654 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 6704
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ + I + G Y + V +G + + + GEK P V S+
Sbjct: 6705 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 6759
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
G S + + T+ W + ++ + + + + G+T + I K + D+G+Y
Sbjct: 6760 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 6818
Query: 804 TLK-AENSEGIAETSAVI 820
K + + IA+ +A +
Sbjct: 6819 VAKVVKEKKAIAKYAAAL 6836
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
VE E D W R + P N Y+ RK R +V+D G D++
Sbjct: 5538 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 5595
Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
E P+I++ L + G TFE E++ RWFK E+ ++ L
Sbjct: 5596 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 5654
Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
G KQ L I D DDA EY+C NS T N ++ + +P
Sbjct: 5655 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 5709
Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
A + ++IP + + W K IE+ KF++ +D K TL I + +D E
Sbjct: 5710 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 5769
Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
Y V+ ++ T + V V PP+
Sbjct: 5770 YRVVVENSVGSDSGTVNVTVADVPEPPR 5797
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/205 (22%), Positives = 79/205 (38%), Gaps = 14/205 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYC 692
P F++KP Q G D+L+EC L A P+P IAW G + P + + +Y
Sbjct: 5 PRFTQKPSIQQTPTG-DLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-----KTGEKEPPQVIEPLKSMIVR 747
+ L I G Y A N+ GE++ I L + P + + +
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKD 123
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK------ALPTKSDGDTHSITI-LKPKKVKDE 800
G +++ +V P W K+ P+ A+ + T+ + ++ D
Sbjct: 124 GGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDA 183
Query: 801 GVYTLKAENSEGIAETSAVITVEEP 825
G Y N +G + + EEP
Sbjct: 184 GQYRCNIRNDQGETNANLALNFEEP 208
Score = 55.6 bits (128), Expect = 4e-07
Identities = 91/405 (22%), Positives = 154/405 (38%), Gaps = 40/405 (9%)
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
T A S A + + + ++ PP+ + + T + G++ L + +
Sbjct: 349 TTGASASATSATSGGSASSDASRDKYTRPPIVLEASRSQTGRIGGSVVLEVQWQCHSSTI 408
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++ S +Q+F+G +L + + E SG YKC A G+ A V I
Sbjct: 409 IEWYRDGTLVRNSSEYSQSFNGSIAKLQVNKLTEE-KSGLYKCHAKCDYGEGQSSAMVKI 467
Query: 924 ---DVEK--VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE 978
DVE+ + K + Y+ EE K+ L+ +T V+ + K + + E
Sbjct: 468 EQSDVEEELMKHRKDAEDEYQKEEQKSQTLQAETKKRVARRSKSKSKSPAPQAKKSTTSE 527
Query: 979 -GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAI 1035
GR V D+E+ + TIPE R+ +V E D
Sbjct: 528 SGRQEASEVEHKRSSSVRP----DPDEESQLDEIPSSGLTIPEERRRELLGQVGESD--- 580
Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE-----GEYSCI 1090
E++ +++ G KP++ D K+ I + N S DE S
Sbjct: 581 --DEVSESISELPSFAGG---KPRRKTDDKPKKVSIAPV-STNKSSDDEPSTPRRRSSID 634
Query: 1091 LRDESCTAEVTVVELP----------PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRW 1139
+R ES + P P+I+ +N V + A +++ A RW
Sbjct: 635 MRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRW 694
Query: 1140 FKDGSEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGN 1182
FK E+ + DGK+ L + C D G Y+ + N
Sbjct: 695 FKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIEN 739
Score = 55.2 bits (127), Expect = 5e-07
Identities = 60/241 (24%), Positives = 95/241 (39%), Gaps = 31/241 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS----QDFQMYYDDDN 564
AP F +K + TP G + EC +E P+P I W +++PS Q
Sbjct: 4 APRFTQKPSIQQTPTGDLLM-ECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLY 62
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
ATLVI+E D G + C A+N G +++ L
Sbjct: 63 KATLVIKEPNAGDGGAYKCTARNQLGESNANINL---------------------NFAGA 101
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
D + P+F KP+ D G+ I++EC++ + P W+ G + + AI
Sbjct: 102 GGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMG-GLYHAI 160
Query: 685 ESDM--HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
SD+ Y L+I G Y N +GE + + L + E +P + E +
Sbjct: 161 FSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFE--EPDPSERQERKR 218
Query: 743 S 743
S
Sbjct: 219 S 219
Score = 54.8 bits (126), Expect = 6e-07
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V
Sbjct: 2620 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 2677
Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E
Sbjct: 2678 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 2737
Query: 816 TSAVITV-EEPTEEN 829
+ I V ++PT N
Sbjct: 2738 ATVKINVIDKPTSPN 2752
Score = 53.6 bits (123), Expect = 1e-06
Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y + A N G+++ + + + E P ++ ++ + + ++ +P P
Sbjct: 5574 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 5633
Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A +
Sbjct: 5634 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 5691
Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
I + F+ YE ++G+T+ L+ + +W + ++I I +
Sbjct: 5692 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 5751
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
+ D G + +V++ ++ T+ V +PE
Sbjct: 5752 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 5794
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
C L V + +E Y V AVN+ G P +K+K + P +K + ++
Sbjct: 1431 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 1489
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
GE++ + G P P W N KP+KA+ I+K + D G +T+
Sbjct: 1490 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1549
Query: 806 KAENSEGIAETSAVITV 822
+NS G +++A +TV
Sbjct: 1550 TLKNSSGSCDSTATVTV 1566
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P V L + G V FEC++ G PRP+ WF+ + + + + D L+
Sbjct: 5604 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 5662
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
I ++ +DA +TC A N++G S+ L ++
Sbjct: 5663 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 5694
Score = 51.6 bits (118), Expect = 6e-06
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
+ S P+V +G P+++E +++ V + E+ IL+ +V G+P PT W K ++ V +
Sbjct: 646 KTSTPLVPSGASGSA--PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVIS 703
Query: 778 ---LPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEG 812
+DG H++ + K + +DEG YTL EN G
Sbjct: 704 GGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHG 742
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
+I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V
Sbjct: 2027 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 2086
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
V G P P W N KPV + + + + +L+ K G+YTL A N+
Sbjct: 2087 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 2146
Query: 812 GIAETSA-VITVEEPT 826
G + S VI + +P+
Sbjct: 2147 GSDKHSVEVIVLGKPS 2162
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
I LP E P V K P F C+ G P P W R +
Sbjct: 5196 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 5255
Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
S ++ + D V I+EV+ DAG +T N G ++T L+V+AP
Sbjct: 5256 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 5306
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V
Sbjct: 1732 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 1791
Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P P + W K N+ ++ L + + H+I + D G Y L +NS
Sbjct: 1792 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 1851
Query: 811 EGIAETSAVITV-EEPTEEN 829
G E A +TV + P++ N
Sbjct: 1852 HGADEEKANLTVLDRPSKPN 1871
Score = 49.6 bits (113), Expect = 2e-05
Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
+TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y
Sbjct: 6536 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 6595
Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
+ Y C A N G+ +T + ++ +P++ + +E
Sbjct: 6596 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 6655
Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
KH G+ A ++G P EV+W +NG +L N + +I+ +T I
Sbjct: 6656 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 6714
Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
S + Y +E + GT+ V V +L V + + P
Sbjct: 6715 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 6748
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
P +L + + G A F ++ + + L+ W +G I S+ + + K L+
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6603
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
I D D G+Y C NS + A LTV ++P +N LR+ + + +
Sbjct: 6604 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 6663
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
V + +V W + + + +K ++ D + + I D Y
Sbjct: 6664 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 6723
Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
+ + S L V + P + G ++++ +W
Sbjct: 6724 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 6783
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
S+ I+K + K + L IK VE D GIY
Sbjct: 6784 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 6818
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
+ SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++
Sbjct: 5160 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 5219
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
+ + + + VG P PT W +N + + SDG + TI +
Sbjct: 5220 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 5278
Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825
+ D G YT++ N G +A + V+ P
Sbjct: 5279 I-DAGEYTVEVSNPYGSDTATANLVVQAP 5306
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/121 (26%), Positives = 48/121 (39%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +KA N G + S + P + + F VK T+ V P P
Sbjct: 3215 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 3274
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
I W+ N +S + + +N + T + DSG YK VA+N +GK H V
Sbjct: 3275 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 3334
Query: 923 I 923
I
Sbjct: 3335 I 3335
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
T V+K Y VVAVN+ G T + E P+ L K V+ GE ++
Sbjct: 4087 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 4146
Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G
Sbjct: 4147 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 4203
Query: 813 IAETSAVITV 822
AE + ITV
Sbjct: 4204 EAEANIKITV 4213
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+
Sbjct: 1717 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 1762
Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
P FI + + ITVK T++ ++ P+P + W++ N+ + +T
Sbjct: 1763 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 1820
Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
D E I + S + D G+Y+ NS G A +T+
Sbjct: 1821 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 1863
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
G + EC + P P+ W FKG +E+V ++ + D VL I ++
Sbjct: 5618 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 5672
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
YT A N G S L+IKT P+V P K ++GE++ L P+
Sbjct: 5673 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 5728
Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
W K+ + ++ +D ++ I + +D G Y + ENS G + +
Sbjct: 5729 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 5787
Query: 821 TVEEPTEENAEPPLF 835
TV + EPP F
Sbjct: 5788 TVADV----PEPPRF 5798
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
+ N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L
Sbjct: 2911 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 2970
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
+ V G P PTITW PV++ + T K+ D G Y +KAEN G
Sbjct: 2971 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 3030
Query: 813 IAETSAVITV 822
+TV
Sbjct: 3031 TDTAEVKVTV 3040
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
K+E + + A NS G E S + E+ P IN ++ITV+ TI++ +
Sbjct: 4485 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 4544
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
NP P I + N I +E D E+VIT S+ D+G YK A+N GK
Sbjct: 4545 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 4602
Query: 916 S 916
+
Sbjct: 4603 T 4603
Score = 45.2 bits (102), Expect = 5e-04
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)
Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S
Sbjct: 2388 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 2442
Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
+ I +K+K+ +P IE R G P K N K +P
Sbjct: 2443 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 2502
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
GDTH T+ K D + +KA NSEG + ET I + P + P
Sbjct: 2503 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 2556
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
+ N+K+ +E + + A N+ G + S P + P++ E L V+ G ++
Sbjct: 2320 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 2379
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
+ G P P +TW N K + + + + + PK + K G YT+ A N G
Sbjct: 2380 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 2439
Query: 813 IAETSAVITVE-EPTE 827
+ I V+ +PT+
Sbjct: 2440 TDSVTINIKVKSKPTK 2455
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
N+K E + V+AVN G + S P +I P+++ + + ++ G + L
Sbjct: 3793 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 3852
Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
+G P PT TW + P D + + +I P K D G Y LK +N G
Sbjct: 3853 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 3912
Query: 815 ETSAVITVEE 824
E + V++
Sbjct: 3913 EAIFEVIVQD 3922
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G
Sbjct: 4475 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 4534
Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
E++ I GNP+P I N P+ + T D + I I K D G Y +
Sbjct: 4535 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 4594
Query: 807 AENSEG 812
A N G
Sbjct: 4595 ATNKYG 4600
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P
Sbjct: 3214 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 3273
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
P+I WF + + + + + DN L + D+G + VA N +G
Sbjct: 3274 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 3325
Score = 41.9 bits (94), Expect = 0.005
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ ++A+N G+ + S + N P + N QEI VK L V+ P P
Sbjct: 2922 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 2980
Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ITW + + S N DG+ V + S D+G Y A N G + +V
Sbjct: 2981 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 3038
Query: 922 TI 923
T+
Sbjct: 3039 TV 3040
Score = 41.5 bits (93), Expect = 0.006
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
KN + +AL D T ++ LK +E + + A N G + S N
Sbjct: 2301 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 2357
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
P + + TVK T+K + + P P +TW N + I S+ +N I
Sbjct: 2358 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 2415
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
SG Y A+N G S VTI+++
Sbjct: 2416 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 2448
Score = 41.1 bits (92), Expect = 0.008
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT
Sbjct: 2668 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 2726
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A NA G +T ++ +++ P S +G
Sbjct: 2727 IKAVNANGEDEATVKINVIDKPTSPNG 2753
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++ + + YP+ + W + I+ + F + DD ATL I ED G +
Sbjct: 5714 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 5772
Query: 584 VAKNAAGFASSTTELIV 600
V +N+ G S T + V
Sbjct: 5773 VVENSVGSDSGTVNVTV 5789
Score = 40.3 bits (90), Expect = 0.015
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP V+E +S R G SV+L Q + I W ++ V+ S SI L+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 794 PKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEE 828
K+ +E G+Y A+ G ++SA++ +E+ E
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDVE 473
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP F LR + + C ++G P P I W + + +D
Sbjct: 6383 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 6440
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V +L I +DAGT+T A N G S L V+
Sbjct: 6441 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 6478
Score = 39.9 bits (89), Expect = 0.019
Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P KP+ + C V PEP WL G E+ E+ E+ +
Sbjct: 5211 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 5268
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
Y +K V G YTV N G + L ++ PP + + + + I+ G+
Sbjct: 5269 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 5322
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
V L G + N + + PT + D H + + V++ G Y
Sbjct: 5323 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 5382
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G A T + V E + PL I+ T T+ VT ++
Sbjct: 5383 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 5437
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+S E +T + +++ ++T + E +++ A N G
Sbjct: 5438 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 5482
Score = 39.5 bits (88), Expect = 0.026
Identities = 29/153 (18%), Positives = 62/153 (40%), Gaps = 5/153 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+P + ++ E+ + I E ++ V P+ + P + + +TV E T L
Sbjct: 623 EPSTPRRRSSIDMRRESVQEILEKTSTPLV--PSGASGSAPKIVEVPENVTVVENETAIL 680
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIELVITNVDSEIDSGDYKCVASN 910
+V+ +P P+ W++ + + DG+ + L + S+ D G Y N
Sbjct: 681 TCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQ-DEGPYTLTIEN 739
Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
G S ++ + + + + K E++ G
Sbjct: 740 VHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 772
Score = 39.1 bits (87), Expect = 0.034
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T
Sbjct: 2083 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 2139
Query: 583 CVAKNAAGFASSTTELIV 600
A NA+G + E+IV
Sbjct: 2140 LTATNASGSDKHSVEVIV 2157
Score = 39.1 bits (87), Expect = 0.034
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N
Sbjct: 6408 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 6466
Query: 1652 GTSSVEVTLKVYDKPSKP 1669
G E L V K +P
Sbjct: 6467 GVDVSECVLTVQTKGGEP 6484
Score = 38.7 bits (86), Expect = 0.045
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
++ + E ++K P+ S AP VE + T C+V G P P WF
Sbjct: 637 RESVQEILEKTSTPLVPSGASGS-APKIVEVPENVTVVENETAILTCKVSGSPAPTFRWF 695
Query: 545 RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + + F+ D ++ L + + +D G +T +N G S+ +L+V
Sbjct: 696 KGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV--- 752
Query: 604 LSDHG 608
SD+G
Sbjct: 753 TSDNG 757
Score = 38.3 bits (85), Expect = 0.059
Identities = 18/96 (18%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
PP ++ ++Q G E++ ++ W++DG+ ++ S+ + +G KL+
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1165 IYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSI 1196
+ + +G Y C+ G + +A++ +E+ +
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDV 472
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
+ +K Q + V A+N+ GE+ S P + P++ + + V+ G+++
Sbjct: 3204 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 3263
Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
V G P P I W N P+ + T D +T + T L K D G Y + A N
Sbjct: 3264 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 3323
Query: 811 EGIAETSAVITV 822
G E + +
Sbjct: 3324 SGKDEHEVDVNI 3335
Score = 37.5 bits (83), Expect = 0.10
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
KS+ D H + KP K V+D E +Y +KA N G + + + A
Sbjct: 1416 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 1475
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P +++ +K TIK ++ P+P W N + + + + + +
Sbjct: 1476 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 1535
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I N DSG + NS+G A VT+
Sbjct: 1536 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 1566
Score = 37.1 bits (82), Expect = 0.14
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT--KEKTSVIRIKELKRSHSSKYTIEAS 1648
++T + G P P W+K ++ + + T KE T + + + + YT+
Sbjct: 679 ILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIE 738
Query: 1649 NTAGTSSVEVTLKV 1662
N GT S +V L V
Sbjct: 739 NVHGTDSADVKLLV 752
Score = 37.1 bits (82), Expect = 0.14
Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y
Sbjct: 6664 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 6722
Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+L + + V V + +K PP + + SS P G ST + +
Sbjct: 6723 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 6769
Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
E++ ++ T +W + ++++KT ++++ V + D + KV+K
Sbjct: 6770 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 6824
Query: 1476 ETK 1478
E K
Sbjct: 6825 EKK 6827
Score = 36.7 bits (81), Expect = 0.18
Identities = 20/91 (21%), Positives = 36/91 (39%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PP +++ R + G V L V +Q EW + +++ S + A L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ K+ +G+YK + + G V I
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGEGQSSAMVKI 467
Score = 36.7 bits (81), Expect = 0.18
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 4/125 (3%)
Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
R+ + D + E +L+ ST + PKIV+ + L P
Sbjct: 629 RRSSIDMRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGSP 688
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCG--HADV 1371
P W S+ + K D K + +L + K + D G Y L +EN G ADV
Sbjct: 689 APTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADV 748
Query: 1372 EMNVT 1376
++ VT
Sbjct: 749 KLLVT 753
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+E + + A N G ++ S N +P + + + +T+K +I V+
Sbjct: 2620 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 2679
Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+
Sbjct: 2680 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 2737
Query: 917 HGARVTIDVEKVT 929
++ + ++K T
Sbjct: 2738 ATVKINV-IDKPT 2749
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
L+N + N +LTC G P P + W +DG + + R
Sbjct: 6395 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 6454
Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
Y A ND G + CV+ +Q K
Sbjct: 6455 AGTYTVTATNDLGVDVSECVLTVQTK 6480
Score = 36.3 bits (80), Expect = 0.24
Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 4/104 (3%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY--- 560
E +S P FV K R G+ + EC+V+ P W + + + +
Sbjct: 105 EAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDL 164
Query: 561 -DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
D + L IR DAG + C +N G ++ L E P
Sbjct: 165 GDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFEEP 208
Score = 36.3 bits (80), Expect = 0.24
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++
Sbjct: 1760 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 1819
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
+ + L I D G + KN+ G L +++ P +G
Sbjct: 1820 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 1872
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENI---ELVITNVDSEIDSG 902
G + + + +P P+I W + ++ PS + Q G ++ LVI ++ D G
Sbjct: 19 GDLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAG-DGG 77
Query: 903 DYKCVASNSAGKSS 916
YKC A N G+S+
Sbjct: 78 AYKCTARNQLGESN 91
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PP V W+K+ +L+ +Y + I +K +YT+ A N+ GT V L
Sbjct: 6294 PPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 6353
Query: 1661 KV--YDKPSKPE 1670
V + +P K E
Sbjct: 6354 NVTRHSEPLKFE 6365
Score = 35.5 bits (78), Expect = 0.42
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVK 845
H +T L PKK + V A + S IT + PT + ++I
Sbjct: 4772 HRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLT---RDILAY 4828
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDY 904
K++ +P P +T+ + ISP++ + + + +T SE+ D G Y
Sbjct: 4829 AGERAKILVPFAASPAPKVTFSKGENKISPTDPRVK-VEYSDFLATLTIEKSELTDGGLY 4887
Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
NS G S R+ + V+K +H++
Sbjct: 4888 FVELENSQGSDSASIRLKV-VDKPASPQHIR 4917
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++++ + G P P+ W +K +M + + I D+G FT
Sbjct: 1491 GETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMS-SERGKHIMKIENAVRADSGKFTI 1549
Query: 584 VAKNAAGFASST-TELIVEAPLSDHG 608
KN++G ST T +V P G
Sbjct: 1550 TLKNSSGSCDSTATVTVVGRPTPPKG 1575
Score = 34.7 bits (76), Expect = 0.73
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 499 EKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDF 556
++ ++ +++AP I E L G+T++F ++G P P +TW F I +
Sbjct: 2349 DRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQI 2408
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
+ ++ ++ + + + +G +T A N G S T + V++
Sbjct: 2409 E---NEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKS 2451
Score = 33.5 bits (73), Expect = 1.7
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G V G P P ITW F T + S D ++D ++ D GT+
Sbjct: 2965 GQDFSLNIPVSGEPTPTITWTFEGTPV--ESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3022
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A+N G ++ ++ +++ P S G
Sbjct: 3023 IKAENENGTDTAEVKVTVLDHPSSPRG 3049
Score = 33.1 bits (72), Expect = 2.2
Identities = 53/305 (17%), Positives = 115/305 (37%), Gaps = 21/305 (6%)
Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVE 1282
+ WY+ +++ ++ +++ + L + K TE+ +C C + +S+ +K+E
Sbjct: 409 IEWYRDGTLVRNSSEYSQSFNGSIAKLQVNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIE 468
Query: 1283 VVEFPPKIV----DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ +++ D E EY+ + TL QA + SK K S
Sbjct: 469 QSDVEEELMKHRKDAEDEYQKEEQKSQTL----QAETKKRVARRSKSKSKSPAPQAKKST 524
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPSPPGKPNILEIDSSSI 1397
S+S +VE+ + + + ++ + +TI ++ + E D
Sbjct: 525 TSESGRQEASEVEHKRSSSVRPDPDEESQLDEIPSSGLTIPEERRRELLGQVGESDDEVS 584
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
+ P G + D + +S+ ++ ++S T R + +
Sbjct: 585 ESISELPSFAGGKP------RRKTDDKPKKVSIAPVSTNKSSDDEPSTPR--RRSSIDMR 636
Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
+ + E T V +P + + +N+T NE LTC G P P W++
Sbjct: 637 RESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFK 696
Query: 1518 DGKKL 1522
+++
Sbjct: 697 GSREV 701
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/97 (21%), Positives = 34/97 (35%), Gaps = 2/97 (2%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P + P+ V E +L C++ P P W E++ + H
Sbjct: 658 GSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHT 717
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
L + + EG YT+ N G S + L +
Sbjct: 718 V--ALALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 752
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+PP + + V G D L + P P I W F+G + D+ + + E
Sbjct: 2948 VPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTK 3007
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
+ + + GTY + A N G + + + + P
Sbjct: 3008 F----HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSP 3047
Score = 31.5 bits (68), Expect = 6.8
Identities = 34/179 (18%), Positives = 68/179 (37%), Gaps = 15/179 (8%)
Query: 752 VILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGDTHSIT-ILKPKKVKDEGVY 803
+++ + +P+PTI W + + V+ L T G + T ++K D G Y
Sbjct: 21 LLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTL-TPLGGSLYKATLVIKEPNAGDGGAY 79
Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPV 861
A N G + + + + A+ P F+ + + I I + +V
Sbjct: 80 KCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSAST 139
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVD----SEIDSGDYKCVASNSAGKSS 916
P W ++ +S F + + ++ S D+G Y+C N G+++
Sbjct: 140 PVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETN 198
>X15423-1|CAA33463.1| 6048|Caenorhabditis elegans twitchin protein.
Length = 6048
Score = 318 bits (782), Expect = 2e-86
Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)
Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
+K+ + + K +C S +WY ++KEI SG +I+ E
Sbjct: 25 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 84
Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
D G C T L V E + F+ L + E+ A+L ++N+ A +VW
Sbjct: 85 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 144
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
R + I+ ++ EK R L I+ D+ E++ I +D +V V E
Sbjct: 145 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 204
Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
+ +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I
Sbjct: 205 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 264
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
++D GEY C + + A L V+ + F + L + ++ + D L + D
Sbjct: 265 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 322
Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
W++ I KF S TL I K ++ Y + + + V
Sbjct: 323 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 382
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
E P + ++ K G + V +Q P + + N K I + K + I
Sbjct: 383 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 442
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
A + K + D G + L L N+ G A + + DKP PP P + + +
Sbjct: 443 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 502
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N
Sbjct: 503 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 562
Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
E +SD E+ Y K + + V+K + EP E+ I G +
Sbjct: 563 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 622
Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
+ + W++ G+ T K E++ C DHG+
Sbjct: 623 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 675
Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
+ +K + IK + KVG+ I G P PE +W NG L+ +
Sbjct: 676 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 734
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
+++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ +
Sbjct: 735 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 794
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR
Sbjct: 795 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 854
Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
V A N G SE L ++ IK D P D + + I W P K+GG+PI
Sbjct: 855 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 913
Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
+Y VE++ + K+WK A I L YQFR+ A N+ G P +K
Sbjct: 914 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 973
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
P + + S + T++W GG PI E K KG +
Sbjct: 974 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 1027
Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
+T+ +EH CI + D +R++ +N+ G + +V L++ PS P P
Sbjct: 1028 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 1082
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L
Sbjct: 1083 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 1140
Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+ TY R+ A N+ G S+ L +D+ K
Sbjct: 1141 KGQTYQFRVKAVNKEGASDALSTDKDTK 1168
Score = 253 bits (619), Expect = 1e-66
Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)
Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
P ++D +E ++K G D +L + P P W ++ K + +
Sbjct: 2158 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 2217
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
+K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP
Sbjct: 2218 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 2277
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD
Sbjct: 2278 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 2337
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
E E + K+ ++ P + + D++ T GG P V
Sbjct: 2338 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2396
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
A ++ A N GE + S + + + + N
Sbjct: 2397 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 2456
Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K
Sbjct: 2457 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 2516
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG
Sbjct: 2517 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 2576
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L
Sbjct: 2577 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 2633
Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
S+ IV K D P D + V + W P +GG+PI Y VE K + W
Sbjct: 2634 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 2692
Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
A L+ TYQFR+ A N+ G P + P
Sbjct: 2693 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 2752
Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ +K +P+ + T+ + + S H ++
Sbjct: 2753 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 2812
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
D +++I EN G + +V VP P PL+I + +W P
Sbjct: 2813 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 2866
Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
+GG +L Y + D ++ W EVG T K N L Y R+ A N G S+
Sbjct: 2867 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 2924
Query: 2052 PLESDEP 2058
PLE++EP
Sbjct: 2925 PLEAEEP 2931
Score = 251 bits (614), Expect = 5e-66
Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
PKI+ R+ +IK G L VD+ P P W V S + S+
Sbjct: 3040 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 3099
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
+ D+G YKL+++N G + V + D+PS P P + ++ S + W P++
Sbjct: 3100 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 3159
Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+
Sbjct: 3160 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 3219
Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
T E V+ + +P KP + I N+ I++ GG P R D
Sbjct: 3220 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 3275
Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
K + K Y+ +A N G + S + + P
Sbjct: 3276 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 3335
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
+ + + + K G+ ++T P P++ W K G K E TT +T ++
Sbjct: 3336 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 3391
Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
I +RS S I+A N G + + + V DKP PE + +SR + T+ W P
Sbjct: 3392 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 3450
Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+
Sbjct: 3451 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 3509
Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
+ P+VIK D P D V + W P +GGSPI+ Y VE K+
Sbjct: 3510 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 3568
Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
G W + L N TYQFR+ A N G P + +T + P
Sbjct: 3569 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 3628
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
P V + T S L W P +GG+PI YI+E K + WT+ +
Sbjct: 3629 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 3688
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
+N+ EK+E FR+ A N+ G P++ S V +E+ P
Sbjct: 3689 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 3728
Score = 250 bits (612), Expect = 8e-66
Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y
Sbjct: 1289 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 1347
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
L N G + V +L KPS P G + + ++ W PE+ G + I +Y +
Sbjct: 1348 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 1407
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ +
Sbjct: 1408 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 1465
Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
+ P V+KP + + D+ GG P + K + + A ++
Sbjct: 1466 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 1525
Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
++ A N G + S VV + I ED+ KVG
Sbjct: 1526 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 1585
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
I+G P P+V W NG + K I + S + + R S KYTI A+
Sbjct: 1586 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 1644
Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK
Sbjct: 1645 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 1704
Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
+ W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D
Sbjct: 1705 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 1761
Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
P D++ V + W P +GG+PI +Y++E + + +W+ A
Sbjct: 1762 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 1820
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
+ L+ N Y+FR+ A N+ G S P + + P R+ + + + ++
Sbjct: 1821 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 1880
Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
+ P S +P +T + + + ++ K+ + ++ ++ D F I A
Sbjct: 1881 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 1939
Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I
Sbjct: 1940 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 1994
Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
D W+ KV + + L H Y R+ A N G S+PLE+
Sbjct: 1995 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 2046
Score = 243 bits (595), Expect = 1e-63
Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
R+K G + V+ + P P EW +N + +T ++ + LT K D+G
Sbjct: 2464 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 2523
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y
Sbjct: 2524 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 2583
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
VVE QE D W+ + T + L Y+FR AVN S + T + ++
Sbjct: 2584 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 2640
Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
+ P + + + + D+E GG P + +D G ++ A+
Sbjct: 2641 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 2700
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
+ ++ A N G + S G + KP ++ +
Sbjct: 2701 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 2759
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
K G + EG P P W N ++ ++T +S I I R + Y
Sbjct: 2760 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 2819
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E
Sbjct: 2820 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 2879
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K
Sbjct: 2880 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 2937
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
DVP D + + I W P+ NGG+P+ Y VE K++G W
Sbjct: 2938 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 2996
Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
L Y+FR+ A N G S P +D +IT + L P + R + +
Sbjct: 2997 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 3056
Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
++ + + P + + + + +V S + K D ++
Sbjct: 3057 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 3111
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
+ +N +G E +++ PS P PLE+ V + + +W P+ DGGA +
Sbjct: 3112 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 3166
Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP
Sbjct: 3167 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 3224
Score = 242 bits (593), Expect = 2e-63
Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+K G+ + +V P P+ W N K I + K + + + + K +G Y
Sbjct: 1581 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 1639
Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+ N G V +N+ + KP+ P P + ++ + W PE+ G I +Y +
Sbjct: 1640 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 1699
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
E W+ T ++ +L Y+FR AVN SD ET ++ +
Sbjct: 1700 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 1757
Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
P ++P + T+ + D ++L GG P + + K + + A
Sbjct: 1758 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 1815
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
+ ++ +A N G + S V+ + I + +K K
Sbjct: 1816 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 1875
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + G P P V W+ N+ + N + E S + +K+++R S +T
Sbjct: 1876 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 1935
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE
Sbjct: 1936 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 1995
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K
Sbjct: 1996 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 2055
Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
D P D + V + W P +GG+PI +Y VE+K E W
Sbjct: 2056 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 2114
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A + L + Y+FRI A+N+ G P S + + + PP RN +
Sbjct: 2115 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 2173
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
P S +P + E V+ K+ G H ++ D + I
Sbjct: 2174 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 2232
Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
AEN G T V + H PS P PL++ + + +W PE DGGA +
Sbjct: 2233 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 2287
Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E
Sbjct: 2288 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 2342
Score = 235 bits (575), Expect = 3e-61
Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)
Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
+ RIK G+ + L + ++ P P +W N I + S+++ I D
Sbjct: 2756 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 2815
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++
Sbjct: 2816 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 2875
Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
Y+VE + W V + L Y FR AVN S E E
Sbjct: 2876 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 2935
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
+ + P V+KP + DI+ T GG P VT Y KK K + E
Sbjct: 2936 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 2991
Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
++ IA N G + S Q KP I ++ IK
Sbjct: 2992 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 3051
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
K V + G P P W + E + K T+ I KR+ S
Sbjct: 3052 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 3109
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y
Sbjct: 3110 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 3169
Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
+EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K
Sbjct: 3170 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 3228
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
P DN+ + I W P NGGSP+ Y +E K + G+ K
Sbjct: 3229 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 3287
Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
A R+QK TY++R+ A N+ G P S T P +
Sbjct: 3288 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 3344
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
F V +T+ +T SP + I + GK + T S + I +
Sbjct: 3345 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 3395
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
+ D +I A N G + ++++ TV P AP I V + +W
Sbjct: 3396 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 3447
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G
Sbjct: 3448 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 3506
Query: 2049 LSE 2051
LS+
Sbjct: 3507 LSD 3509
Score = 234 bits (572), Expect = 6e-61
Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + +K G+ V V P P +W N ++ + T + ++ L I
Sbjct: 986 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 1045
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
+D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G
Sbjct: 1046 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 1105
Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T
Sbjct: 1106 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 1164
Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
K+TK ++P ++P K T + + D + + P+ +T Y KK K
Sbjct: 1165 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 1218
Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
+ E ++ ++ A N G E S VV +
Sbjct: 1219 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 1278
Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++
Sbjct: 1279 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 1337
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD
Sbjct: 1338 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 1397
Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
GG + Y IEK + RW+ + T + L EY FRV A N G S+ L
Sbjct: 1398 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 1455
Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
+ I+ K +VP D + V + W + +GG+PI + +E K + +
Sbjct: 1456 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 1513
Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
W+ A + L YQFRI ARN+ GT P D++ P R
Sbjct: 1514 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 1573
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+ + TLK+ +P + K + G+S +I + +
Sbjct: 1574 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 1631
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
K + I+A N G T+S ++ + K + P+ P P+E+ V + W P
Sbjct: 1632 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 1686
Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S
Sbjct: 1687 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 1744
Query: 2051 EPLESD 2056
+PLE++
Sbjct: 1745 DPLETE 1750
Score = 223 bits (545), Expect = 1e-57
Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
D + IK G ++ V P P W +++ I+ K + L +K++
Sbjct: 1867 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 1926
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G
Sbjct: 1927 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 1986
Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
I YV+E + + W+ + KT + L Y+FR V V+ S+
Sbjct: 1987 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 2043
Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
E + T + +KP K IT + ++L GG P + V +D
Sbjct: 2044 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 2099
Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
+ ++ A N G S V + P
Sbjct: 2100 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 2159
Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
+ N + K K G ++ + + G P P + W G +E+D + ++ + +
Sbjct: 2160 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 2219
Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D
Sbjct: 2220 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 2279
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+
Sbjct: 2280 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 2337
Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
LE+ E I+ K D + D + + W P +GG+PI Y VE++
Sbjct: 2338 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2396
Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
W A + L TYQFR+ A N+ G S P + P
Sbjct: 2397 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 2456
Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
R+ V++ TL + +P + + + T I + + ++
Sbjct: 2457 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 2516
Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
D ++I A N G + V + +P P PL + + V+ W
Sbjct: 2517 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 2571
Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G
Sbjct: 2572 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 2628
Query: 2050 SEPLESD 2056
S PL SD
Sbjct: 2629 SAPLTSD 2635
Score = 209 bits (510), Expect = 2e-53
Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)
Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
++ ++ G + + + Y P+P + + I + + T ++ +T + +
Sbjct: 3736 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 3795
Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I
Sbjct: 3796 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 3855
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET +
Sbjct: 3856 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 3912
Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
++ + +P +P T+E ++ T GG P Q V R+ + KA
Sbjct: 3913 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 3972
Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
+ N Y + A+N G+ E S + P N + +
Sbjct: 3973 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 4032
Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
+ G+ + P P+V + K NK+ D + + + + I++ + +
Sbjct: 4033 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 4092
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T
Sbjct: 4093 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 4151
Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++
Sbjct: 4152 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 4210
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
+V K +VP+ D+ + W P ++GGS II Y+V+ + +W
Sbjct: 4211 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 4268
Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
AR+ L N ++FRI A+N G S P ++ + PP P +
Sbjct: 4269 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 4328
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
T+ W P +GGS IT Y +E + WT E ++ ++E
Sbjct: 4329 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 4388
Query: 1934 DEIIFRISAENTVGVSLPT 1952
++ FR+ A N G +P+
Sbjct: 4389 NDYEFRVVAINAAGKGIPS 4407
Score = 199 bits (485), Expect = 2e-50
Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
+D + +L + + N ++++ NN G ++ + I D +P PG+P I +
Sbjct: 833 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 892
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F
Sbjct: 893 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 952
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
R AVN+ SE +E ++ K I + LK+IT + + GG P P
Sbjct: 953 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 1011
Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
+V W++ ++L+ + T + R Y+ N HG E +
Sbjct: 1012 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 1071
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
+ +P + N ++ D ++ E I Y KL+ + K
Sbjct: 1072 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 1129
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
K + I LK+ + ++ ++A N G S T K YD+P K P ++ +
Sbjct: 1130 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 1188
Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
+ V++EW+PP DGG +T+Y IEK W + V D I L E EY F
Sbjct: 1189 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 1248
Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
RV A N G EA + S +V K P ID E++ + K G
Sbjct: 1249 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 1295
Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
D V + KK W RI+ T + R R G T+ +
Sbjct: 1296 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1355
Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
DK ++ L PS P VS L+W PE +GG+PI +Y IE +
Sbjct: 1356 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 1415
Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
W V G S + + N++ E FR+ A N G S P + + L K+ VP
Sbjct: 1416 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 1472
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
P E+ + V +W P+ DGGAP+ + I +D W E V + +
Sbjct: 1473 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 1529
Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+L E Y RI ARN+ G +P + +
Sbjct: 1530 PNLKEGEEYQFRISARNKAGTGDPSDPSD 1558
Score = 191 bits (465), Expect = 5e-48
Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)
Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
W + ++D +K + S+ K ++R T YT +A + K VEV+
Sbjct: 1311 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 1369
Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
P ++ Y + +D+ V P D + + + + P S++
Sbjct: 1370 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 1426
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
T+ ++ +++R N G +D + N IL K P KP +++ D +
Sbjct: 1427 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 1486
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A
Sbjct: 1487 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 1544
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT
Sbjct: 1545 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 1602
Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
W +GK + +KA EN Y A N +G + + ++ KP
Sbjct: 1603 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 1662
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
K +V D + A ++ PP + + +Y+ D + +
Sbjct: 1663 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 1716
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
+ + L + K+ ++A N+ G S ++ K +D+P +P P +
Sbjct: 1717 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 1775
Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
+ V ++W PPL DGG + +Y IEK RW V T + L N EY FR
Sbjct: 1776 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 1834
Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
V+A N G S+ ++ VI ++ I++ +P +
Sbjct: 1835 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 1894
Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
+ +E G + K ++++ + F I A N G + KI
Sbjct: 1895 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 1951
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
+ T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W
Sbjct: 1952 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 2008
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
V G ++ + E FR++A N G S P E+ L K P AP EI
Sbjct: 2009 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 2067
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ V W P DGGAP+ Y + ++D W +V V + +L E
Sbjct: 2068 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 2127
Query: 2036 TYMIRIYARNEIGLSEPLES 2055
Y RI A+N+ GL +P +S
Sbjct: 2128 KYEFRIRAKNKAGLGDPSDS 2147
Score = 190 bits (463), Expect = 9e-48
Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI
Sbjct: 3476 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 3534
Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N
Sbjct: 3535 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 3594
Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+Y+FR AVN + S +E V K +P V K KN + E + L
Sbjct: 3595 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 3653
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
GG P + + KKL T N ++ IA N GE
Sbjct: 3654 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 3709
Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
E S +V I++ +P+ I+N +DI + G+ + G P +I NGN
Sbjct: 3710 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 3767
Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
EN++ + VI KRS + Y I A+N G + ++ + V D P KP
Sbjct: 3768 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 3826
Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++
Sbjct: 3827 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 3883
Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
L+ N Y FRV A+N G E LE+ + IV K D P E++ + W
Sbjct: 3884 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 3942
Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
+GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N
Sbjct: 3943 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 4002
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
G + IT T P + + + K P + +P +
Sbjct: 4003 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 4062
Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ V + IE + D ++ + EN+ G ++S S+RL+
Sbjct: 4063 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 4114
Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
V P +P IR+ + + W P DGG+P+ Y + D+ + W +V
Sbjct: 4115 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 4173
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
V L + + L +++ Y R+ A + G+SEP E
Sbjct: 4174 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 4207
Score = 183 bits (445), Expect = 1e-45
Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I
Sbjct: 3191 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 3250
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
+I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A
Sbjct: 3251 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 3310
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
VN+ S+++ + ++P + L K + E + +T F PQP +
Sbjct: 3311 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 3368
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
+W ++G K T +++ K A N +GE E + + + KP
Sbjct: 3369 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 3428
Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
+ +H W G E+ YK + + ++ + +
Sbjct: 3429 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 3485
Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
++ L+ ++ I A N G S V V +K +D P P P I + + V++
Sbjct: 3486 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 3544
Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A
Sbjct: 3545 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 3603
Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
N G E SEP+ + ++ P N S +TW ++GG+PI Y
Sbjct: 3604 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 3662
Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
VE K+ G W ++ L Y+FR+ A N G P D + I
Sbjct: 3663 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 3722
Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
+ P N + + T++ P + G PI + + T +V V
Sbjct: 3723 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 3781
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
K D ++ISA N G + V P PT P+ +
Sbjct: 3782 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 3836
Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y
Sbjct: 3837 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 3893
Query: 2040 RIYARNEIGLSEPLESDE 2057
R+ A N+ G+ EPLE+D+
Sbjct: 3894 RVRAENQYGVGEPLETDD 3911
Score = 178 bits (434), Expect = 3e-44
Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D P P KP + + D I+I W+ N G + + Y+VE +E + W T
Sbjct: 2939 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 2998
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S NLK Y FR AVN SD S+ T+ I + + P + + I +
Sbjct: 2999 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 3056
Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
L F G P P TW D + + + YK N
Sbjct: 3057 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 3116
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ GE E V +Q +P + +V D + V+ PP + + N +
Sbjct: 3117 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 3170
Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
++ T S I + +L H ++ + A NT G S S+ V K
Sbjct: 3171 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 3230
Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV
Sbjct: 3231 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 3289
Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
+ ++ + Y +RV+A N G + +S K + P
Sbjct: 3290 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 3349
Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
E + IT P SP D + +EG K + I + +
Sbjct: 3350 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 3403
Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
+I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I
Sbjct: 3404 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 3457
Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S +
Sbjct: 3458 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 3515
Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
V ++ P P+ P EI +N V +W P DGG+P+LGY + W
Sbjct: 3516 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 3574
Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
V V + + L EN TY R+ A N G EP EP P
Sbjct: 3575 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 3622
Score = 176 bits (428), Expect = 2e-43
Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+I+ + ++ +A F E + + RW ++G E+ S+ + K I
Sbjct: 4423 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 4482
Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
+ DAGEY+ EV G+ TA L V+ P + +P IL + Y +
Sbjct: 4483 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 4541
Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
P V ++ + T + D T+ E + EYT ++TT
Sbjct: 4542 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 4601
Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
+ V P + I T + ++ P + + S +++K +K
Sbjct: 4602 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 4655
Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
+ + + +K + G+ Y+ R+ EN G V + I P PP P
Sbjct: 4656 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 4715
Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
I+++ + + W P + G + Y+VE QE + EW + + NL
Sbjct: 4716 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 4775
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
YR+R +AVN+ +SD +E + + + P + PL ++ E + C
Sbjct: 4776 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 4834
Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
G P+P+ W++ K+L T+K T N+ Y C A N G
Sbjct: 4835 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 4894
Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
T + I+ KP + I + + + G+ + + P E W K+G K+EN+ +
Sbjct: 4895 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 4954
Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I
Sbjct: 4955 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 5013
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y
Sbjct: 5014 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 5070
Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
FR+IA+N G S+ E + P++I
Sbjct: 5071 EFRIIAENKHGQSKPCEPTAPVLI 5094
Score = 171 bits (416), Expect = 5e-42
Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)
Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+++R N GH + VT ++KP P P + +I +S + W+ P G +
Sbjct: 3598 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 3657
Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++
Sbjct: 3658 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 3717
Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
V+ E + P + LK+IT E I++ + GG P+P + + + +
Sbjct: 3718 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 3775
Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
T YK A N +G+ V+ KP I DI
Sbjct: 3776 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 3835
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
Q + W G + I K ++ + +R++ L +
Sbjct: 3836 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 3890
Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
++ + A N G T V +D P P P + E S E++T++W P DG
Sbjct: 3891 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 3949
Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
G + Y IEK E + W K A + + + L Y FRV A N G E ++
Sbjct: 3950 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 4009
Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
S PI A P + +P + + +I
Sbjct: 4010 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 4069
Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
+ K I+K + + + N G SD K + P+ P+
Sbjct: 4070 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 4123
Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
+ V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + +
Sbjct: 4124 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 4182
Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
+ + + FR+ AE GVS P E V + K+ VP+ P AP +R S W
Sbjct: 4183 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 4241
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N
Sbjct: 4242 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 4299
Query: 2047 IGLSEPLESDE 2057
G S+P E
Sbjct: 4300 AGFSKPSPPSE 4310
Score = 163 bits (396), Expect = 1e-39
Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++
Sbjct: 537 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 594
Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
+D + W+ PE G + I Y++E +E +W V + + K + Y
Sbjct: 595 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 654
Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
+R AVN+ D + + K+ K K +K++ + E I+ G P
Sbjct: 655 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 713
Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
P+ W +GK LK ++ + + N G +++ V
Sbjct: 714 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 773
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
+ +P DI G + P + ++N +Y K
Sbjct: 774 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 833
Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I +
Sbjct: 834 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 892
Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
+ + I W+PP DGG + +Y +E +PD W +V V D I L E EY
Sbjct: 893 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 950
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
FRV A N G + E + +P+ + W K GG
Sbjct: 951 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 1008
Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
PI + K +++ + I + ++R+ +N G
Sbjct: 1009 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 1064
Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+
Sbjct: 1065 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 1122
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
W V + H I+ +K+ FR+ A N G S + K+ T
Sbjct: 1123 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 1179
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
++ ++ V W P+ DGGAP+ Y I + W E GKV + I
Sbjct: 1180 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 1239
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
L E Y R+ A N+ G E SD KV+
Sbjct: 1240 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 1269
Score = 142 bits (343), Expect = 3e-33
Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
P PP I + I W P G S I Y VE +E +T W S N+ + +
Sbjct: 4321 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 4380
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
++ L+ + Y FR A+N S + K+ + + V KP T +P N
Sbjct: 4381 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 4438
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
TC G P+P W R+G++L ++++ +E Y
Sbjct: 4439 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 4498
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
N +G + + +Q PVI +D+ GD + G P N +
Sbjct: 4499 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 4555
Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
++ D I + +I I L + +Y SN +G ++ L V P P+G
Sbjct: 4556 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 4615
Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L
Sbjct: 4616 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 4674
Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
EN EY FRV AQN G L SE PI+ + D P + + V ++W
Sbjct: 4675 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 4733
Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
+GG + Y VE ++E +W + L Y++R++A N+ G
Sbjct: 4734 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 4793
Query: 1848 S 1848
S
Sbjct: 4794 S 4794
Score = 132 bits (320), Expect = 2e-30
Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)
Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
K T KL V V++ P K R I+ + + + ++ P+ N + + +++K
Sbjct: 3810 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 3865
Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
+ T +V N DA +++R EN G + +E + I+ D P P
Sbjct: 3866 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 3925
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ +
Sbjct: 3926 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 3985
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
L +Y FR A N + S + + + P + + ++I E +
Sbjct: 3986 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 4043
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
+ F P PKVT+ + K+ K Y + Y N
Sbjct: 4044 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 4103
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
G S + + KP S + I+ + D W+ + G P I K
Sbjct: 4104 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 4160
Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
+ + K +++ + + L + + ++ + A G S V V ++
Sbjct: 4161 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 4220
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D +
Sbjct: 4221 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 4277
Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
+ + L +N E+ FR+IA+N GFS+ + SE +K+ P I
Sbjct: 4278 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 4336
Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
ITW ++GGS I Y VEI++ G W + KL Y+FR+
Sbjct: 4337 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 4396
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A N G +P I I + + S+P+ V E T++
Sbjct: 4397 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 4434
Score = 129 bits (311), Expect = 2e-29
Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ +
Sbjct: 4206 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 4264
Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
WI+ K Q + L+ N + FR A N S S +E ++ P
Sbjct: 4265 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 4324
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
+ K+I + + G K+T Y R+ G L T + Y R
Sbjct: 4325 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 4382
Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
++ +A N G+ S G IQ+ +P I + ED Q + +
Sbjct: 4383 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 4442
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
AV G P P W +NG +L Y + IKE+ + +YT+E SN
Sbjct: 4443 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 4500
Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
G+ + L V P PVI +++ TI L G L K P
Sbjct: 4501 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 4546
Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
+ + ++D D T I + +++ ++ G E S T L+V
Sbjct: 4547 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 4606
Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
P I + ++W P +GGS I Y VE + K +W
Sbjct: 4607 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 4666
Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
I L N Y+FR+ A+NE G P S+ I PP+ P N + +
Sbjct: 4667 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 4726
Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
VTL W P S+GG + YI+E + + W + + + + N+ + + +R+
Sbjct: 4727 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 4786
Query: 1942 AENTVGVS 1949
A N G+S
Sbjct: 4787 AVNDAGLS 4794
Score = 124 bits (299), Expect = 7e-28
Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)
Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
W P +GGSPI +Y K++++ KW K + L + Y+FR+ A
Sbjct: 4139 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 4198
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
+ G S P D + P+QP V + S L+W +P +GGS I Y ++
Sbjct: 4199 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 4257
Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
++ W + + E C + +++ E FRI A+N G S P+ S+ +L
Sbjct: 4258 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 4314
Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
+ P PP + + +G N +W P DGG+ + GYN+ IR+ T+W
Sbjct: 4315 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 4373
Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
+V +F + L E + Y R+ A N G P P K+ GS
Sbjct: 4374 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 4421
Score = 99 bits (238), Expect = 2e-20
Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)
Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P I WY++ + I + +N+ +I N D+G Y C A+ G +H
Sbjct: 45 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 101
Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
++ K +F+ L + E K +L C+ + WY K I D R II+
Sbjct: 102 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 161
Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
+ GR I +D + + V+E F+ ++ +V E D+A
Sbjct: 162 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 221
Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+
Sbjct: 222 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 281
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
A++ +V+ + I L++ +V + + T + WF++G +I
Sbjct: 282 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 340
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+ LKI ++++A Y + + + +TV E
Sbjct: 341 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 381
Score = 99.1 bits (236), Expect = 3e-20
Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)
Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ +
Sbjct: 485 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 542
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
++++KE E FR+ A N G+S P +SV + VP P ++ V +
Sbjct: 543 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 601
Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
+W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A
Sbjct: 602 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 661
Query: 2045 NEIGLSEPLESDEPFKV 2061
N+ G +P + +P K+
Sbjct: 662 NKAGPGDPCDHGKPIKM 678
Score = 98.3 bits (234), Expect = 5e-20
Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
+S + TL W P ++GGS IT+Y++E + + W VTV +V + + + +
Sbjct: 4619 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 4675
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW
Sbjct: 4676 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 4732
Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P DGG L GY + ++ W + +N+ +L + Y R++A N+ G
Sbjct: 4733 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 4792
Query: 2049 LSEPLESDEPFKVIPGEG 2066
LS+ E D+ G G
Sbjct: 4793 LSDLAELDQTLFQASGSG 4810
Score = 94.3 bits (224), Expect = 9e-19
Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)
Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
L D+ +T+ K + L +H ++ + A N G S + ++ +D P
Sbjct: 4652 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 4711
Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
+ P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y
Sbjct: 4712 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 4770
Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
+ L + +Y +RV A N G S+ E + + + A ++ E
Sbjct: 4771 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 4829
Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
F E + GSP +Y+ + + K+ I L+ + ++ A
Sbjct: 4830 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 4888
Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
N GT + T + PP + + T++ P +
Sbjct: 4889 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 4944
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + ++ S I T I N +D +R+ EN+VG T + +V
Sbjct: 4945 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 4998
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K
Sbjct: 4999 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 5057
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
I L Y RI A N+ G S+P E P +IPG+
Sbjct: 5058 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 5097
Score = 89.8 bits (213), Expect = 2e-17
Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
T LDVP I E + W P NGG+ ++ Y VE + W+
Sbjct: 2836 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 2895
Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
A++ KL Y FR+ A N G S P +++ I P V++
Sbjct: 2896 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 2955
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
+ +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+
Sbjct: 2956 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 3013
Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
A N G S P++ ++ K + P TA +I++ N+ + G P+
Sbjct: 3014 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 3068
Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
P + + + V K ++ F +++ Y +++ +NE+G E
Sbjct: 3069 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 3121
Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
+ F+VI + A E P E ++V
Sbjct: 3122 EAIFEVIVQDRPSAPEGPLEVSDV 3145
Score = 88.6 bits (210), Expect = 4e-17
Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ +
Sbjct: 5472 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 5530
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
+TI + K D+G YT++A+NS G E + V +E PL E K
Sbjct: 5531 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 5583
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
++ R P T++ N +I + +T + G + D D
Sbjct: 5584 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 5643
Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
V+ S S +D + T+ + + V+ TV TK
Sbjct: 5644 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 5695
Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
+S R + + G +I+ + D + + L K T +P F
Sbjct: 5696 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 5755
Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
+L D E + A ++ + ++ W +GE I +++ L I +
Sbjct: 5756 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 5815
Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
DEG+Y C + E A +TV VE + L + VN
Sbjct: 5816 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 5875
Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV
Sbjct: 5876 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 5935
Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
+ +++ V E + RLP + P T+E + E L V W++
Sbjct: 5936 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 5995
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
IE E+ + L I+ +DD Y ++ K
Sbjct: 5996 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 6035
Score = 87.8 bits (208), Expect = 7e-17
Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S
Sbjct: 4836 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 4895
Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
L++ KP P +++ TIE K P ++ + + +NN
Sbjct: 4896 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 4955
Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
+ D+ T I + +RV+ +N VG V T DVP
Sbjct: 4956 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 5009
Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
+D E+V ++W P +GGS + +Y +E ++ G W I+ L
Sbjct: 5010 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 5068
Query: 1834 TYQFRIYARNEIGTSLP 1850
Y+FRI A N+ G S P
Sbjct: 5069 QYEFRIIAENKHGQSKP 5085
Score = 70.5 bits (165), Expect = 1e-11
Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
+P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V +
Sbjct: 4609 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 4667
Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
+ + L ENH Y R+ A+NE G+ PL S+ P
Sbjct: 4668 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 4701
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP
Sbjct: 4783 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 4842
Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
W CK + GD + I+ D YT +A NS G T A +
Sbjct: 4843 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 4901
Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
++ +P +FI ++ +KG TI+L P W ++ E I +
Sbjct: 4902 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 4955
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ D + L I+N E D G+Y+ V NS G S VT+
Sbjct: 4956 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 4998
Score = 66.9 bits (156), Expect = 1e-10
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ K +G + F C+V P +TW + +K S + Y+ ++ L
Sbjct: 5475 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 5533
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I V +D G +T AKN+ G T E IV ++ H + +
Sbjct: 5534 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 5589
Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
E P F+ + + + + L C L P P I W+ G V ++ + V+
Sbjct: 5590 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 5648
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
S + CS L+I N + GTYTV A N G VL ++T EP P+V
Sbjct: 5649 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 5697
Score = 66.5 bits (155), Expect = 2e-10
Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P+F+ + + G + PEP I WL GE I ++ + +
Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 5809
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
L+I++ KK EG Y A N G+ L +K + + +V + L
Sbjct: 5810 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 5869
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
IV GESV A+V G P + W +N + + DG+T S TI D
Sbjct: 5870 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 5927
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
G Y L+ S+G S V E A+PP + R ++ G+
Sbjct: 5928 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 5982
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
++ W+R +E I +E + G +L I NV+ + D G Y
Sbjct: 5983 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 6027
Score = 62.9 bits (146), Expect = 2e-09
Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
E P L G S SA V G P P I W N + + ++ T
Sbjct: 5751 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 5810
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
+ + K DEG Y +A NS G +T A +TV ++P + E L + +
Sbjct: 5811 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 5870
Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
+ G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+
Sbjct: 5871 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 5928
Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
G Y+ V S S + V + + V L S G + +E + ++
Sbjct: 5929 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 5988
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
+W+ ++I + + ++ G D G+ + +VK+++
Sbjct: 5989 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 6036
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
P F +L T G + +F V G P P I W I S F+ Y ATL
Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 5811
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
I + D G + C A N+AG + L V + PL + + V
Sbjct: 5812 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 5862
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
+K + V+ G + E R+ PE ++ W+ G+E+ + S++ +
Sbjct: 5863 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 5913
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ + I + G Y + V +G + + + GEK P V S+
Sbjct: 5914 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 5968
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
G S + + T+ W + ++ + + + + G+T + I K + D+G+Y
Sbjct: 5969 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 6027
Query: 804 TLK-AENSEGIAETSAVI 820
K + + IA+ +A +
Sbjct: 6028 VAKVVKEKKAIAKYAAAL 6045
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
VE E D W R + P N Y+ RK R +V+D G D++
Sbjct: 4747 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 4804
Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
E P+I++ L + G TFE E++ RWFK E+ ++ L
Sbjct: 4805 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 4863
Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
G KQ L I D DDA EY+C NS T N ++ + +P
Sbjct: 4864 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 4918
Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
A + ++IP + + W K IE+ KF++ +D K TL I + +D E
Sbjct: 4919 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 4978
Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
Y V+ ++ T + V V PP+
Sbjct: 4979 YRVVVENSVGSDSGTVNVTVADVPEPPR 5006
Score = 54.8 bits (126), Expect = 6e-07
Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V
Sbjct: 1829 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 1886
Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E
Sbjct: 1887 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 1946
Query: 816 TSAVITV-EEPTEEN 829
+ I V ++PT N
Sbjct: 1947 ATVKINVIDKPTSPN 1961
Score = 53.6 bits (123), Expect = 1e-06
Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y + A N G+++ + + + E P ++ ++ + + ++ +P P
Sbjct: 4783 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 4842
Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A +
Sbjct: 4843 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 4900
Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
I + F+ YE ++G+T+ L+ + +W + ++I I +
Sbjct: 4901 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 4960
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
+ D G + +V++ ++ T+ V +PE
Sbjct: 4961 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 5003
Score = 52.8 bits (121), Expect = 3e-06
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
C L V + +E Y V AVN+ G P +K+K + P +K + ++
Sbjct: 640 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 698
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
GE++ + G P P W N KP+KA+ I+K + D G +T+
Sbjct: 699 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 758
Query: 806 KAENSEGIAETSAVITV 822
+NS G +++A +TV
Sbjct: 759 TLKNSSGSCDSTATVTV 775
Score = 52.4 bits (120), Expect = 3e-06
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P V L + G V FEC++ G PRP+ WF+ + + + + D L+
Sbjct: 4813 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 4871
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
I ++ +DA +TC A N++G S+ L ++
Sbjct: 4872 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 4903
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
+I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V
Sbjct: 1236 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 1295
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
V G P P W N KPV + + + + +L+ K G+YTL A N+
Sbjct: 1296 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1355
Query: 812 GIAETSA-VITVEEPT 826
G + S VI + +P+
Sbjct: 1356 GSDKHSVEVIVLGKPS 1371
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
I LP E P V K P F C+ G P P W R +
Sbjct: 4405 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 4464
Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
S ++ + D V I+EV+ DAG +T N G ++T L+V+AP
Sbjct: 4465 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 4515
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V
Sbjct: 941 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 1000
Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P P + W K N+ ++ L + + H+I + D G Y L +NS
Sbjct: 1001 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 1060
Query: 811 EGIAETSAVITV-EEPTEEN 829
G E A +TV + P++ N
Sbjct: 1061 HGADEEKANLTVLDRPSKPN 1080
Score = 49.6 bits (113), Expect = 2e-05
Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)
Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
+TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y
Sbjct: 5745 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 5804
Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
+ Y C A N G+ +T + ++ +P++ + +E
Sbjct: 5805 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 5864
Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
KH G+ A ++G P EV+W +NG +L N + +I+ +T I
Sbjct: 5865 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 5923
Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
S + Y +E + GT+ V V +L V + + P
Sbjct: 5924 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 5957
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
P +L + + G A F ++ + + L+ W +G I S+ + + K L+
Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 5812
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
I D D G+Y C NS + A LTV ++P +N LR+ + + +
Sbjct: 5813 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 5872
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
V + +V W + + + +K ++ D + + I D Y
Sbjct: 5873 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 5932
Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
+ + S L V + P + G ++++ +W
Sbjct: 5933 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 5992
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
S+ I+K + K + L IK VE D GIY
Sbjct: 5993 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 6027
Score = 48.8 bits (111), Expect = 4e-05
Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
+ SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++
Sbjct: 4369 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 4428
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
+ + + + VG P PT W +N + + SDG + TI +
Sbjct: 4429 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 4487
Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825
+ D G YT++ N G +A + V+ P
Sbjct: 4488 I-DAGEYTVEVSNPYGSDTATANLVVQAP 4515
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/121 (26%), Positives = 48/121 (39%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +KA N G + S + P + + F VK T+ V P P
Sbjct: 2424 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 2483
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
I W+ N +S + + +N + T + DSG YK VA+N +GK H V
Sbjct: 2484 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 2543
Query: 923 I 923
I
Sbjct: 2544 I 2544
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
T V+K Y VVAVN+ G T + E P+ L K V+ GE ++
Sbjct: 3296 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 3355
Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G
Sbjct: 3356 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 3412
Query: 813 IAETSAVITV 822
AE + ITV
Sbjct: 3413 EAEANIKITV 3422
Score = 47.2 bits (107), Expect = 1e-04
Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)
Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+
Sbjct: 926 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 971
Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
P FI + + ITVK T++ ++ P+P + W++ N+ + +T
Sbjct: 972 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 1029
Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
D E I + S + D G+Y+ NS G A +T+
Sbjct: 1030 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 1072
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
G + EC + P P+ W FKG +E+V ++ + D VL I ++
Sbjct: 4827 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 4881
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
YT A N G S L+IKT P+V P K ++GE++ L P+
Sbjct: 4882 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 4937
Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
W K+ + ++ +D ++ I + +D G Y + ENS G + +
Sbjct: 4938 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 4996
Query: 821 TVEEPTEENAEPPLF 835
TV + EPP F
Sbjct: 4997 TVADV----PEPPRF 5007
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
+ N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L
Sbjct: 2120 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 2179
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
+ V G P PTITW PV++ + T K+ D G Y +KAEN G
Sbjct: 2180 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 2239
Query: 813 IAETSAVITV 822
+TV
Sbjct: 2240 TDTAEVKVTV 2249
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
K+E + + A NS G E S + E+ P IN ++ITV+ TI++ +
Sbjct: 3694 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 3753
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
NP P I + N I +E D E+VIT S+ D+G YK A+N GK
Sbjct: 3754 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 3811
Query: 916 S 916
+
Sbjct: 3812 T 3812
Score = 45.2 bits (102), Expect = 5e-04
Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)
Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S
Sbjct: 1597 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 1651
Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
+ I +K+K+ +P IE R G P K N K +P
Sbjct: 1652 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 1711
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
GDTH T+ K D + +KA NSEG + ET I + P + P
Sbjct: 1712 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 1765
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)
Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
+ N+K+ +E + + A N+ G + S P + P++ E L V+ G ++
Sbjct: 1529 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 1588
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
+ G P P +TW N K + + + + + PK + K G YT+ A N G
Sbjct: 1589 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 1648
Query: 813 IAETSAVITVE-EPTE 827
+ I V+ +PT+
Sbjct: 1649 TDSVTINIKVKSKPTK 1664
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
N+K E + V+AVN G + S P +I P+++ + + ++ G + L
Sbjct: 3002 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 3061
Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
+G P PT TW + P D + + +I P K D G Y LK +N G
Sbjct: 3062 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 3121
Query: 815 ETSAVITVEE 824
E + V++
Sbjct: 3122 EAIFEVIVQD 3131
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G
Sbjct: 3684 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 3743
Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
E++ I GNP+P I N P+ + T D + I I K D G Y +
Sbjct: 3744 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 3803
Query: 807 AENSEG 812
A N G
Sbjct: 3804 ATNKYG 3809
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)
Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P
Sbjct: 2423 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 2482
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
P+I WF + + + + + DN L + D+G + VA N +G
Sbjct: 2483 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 2534
Score = 41.9 bits (94), Expect = 0.005
Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ ++A+N G+ + S + N P + N QEI VK L V+ P P
Sbjct: 2131 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 2189
Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ITW + + S N DG+ V + S D+G Y A N G + +V
Sbjct: 2190 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 2247
Query: 922 TI 923
T+
Sbjct: 2248 TV 2249
Score = 41.5 bits (93), Expect = 0.006
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
KN + +AL D T ++ LK +E + + A N G + S N
Sbjct: 1510 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 1566
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
P + + TVK T+K + + P P +TW N + I S+ +N I
Sbjct: 1567 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 1624
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
SG Y A+N G S VTI+++
Sbjct: 1625 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 1657
Score = 41.1 bits (92), Expect = 0.008
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT
Sbjct: 1877 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 1935
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A NA G +T ++ +++ P S +G
Sbjct: 1936 IKAVNANGEDEATVKINVIDKPTSPNG 1962
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++ + + YP+ + W + I+ + F + DD ATL I ED G +
Sbjct: 4923 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 4981
Query: 584 VAKNAAGFASSTTELIV 600
V +N+ G S T + V
Sbjct: 4982 VVENSVGSDSGTVNVTV 4998
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP F LR + + C ++G P P I W + + +D
Sbjct: 5592 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 5649
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V +L I +DAGT+T A N G S L V+
Sbjct: 5650 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 5687
Score = 39.9 bits (89), Expect = 0.019
Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P KP+ + C V PEP WL G E+ E+ E+ +
Sbjct: 4420 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 4477
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
Y +K V G YTV N G + L ++ PP + + + + I+ G+
Sbjct: 4478 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 4531
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
V L G + N + + PT + D H + + V++ G Y
Sbjct: 4532 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 4591
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G A T + V E + PL I+ T T+ VT ++
Sbjct: 4592 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 4646
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+S E +T + +++ ++T + E +++ A N G
Sbjct: 4647 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 4691
Score = 39.1 bits (87), Expect = 0.034
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T
Sbjct: 1292 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 1348
Query: 583 CVAKNAAGFASSTTELIV 600
A NA+G + E+IV
Sbjct: 1349 LTATNASGSDKHSVEVIV 1366
Score = 39.1 bits (87), Expect = 0.034
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N
Sbjct: 5617 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 5675
Query: 1652 GTSSVEVTLKVYDKPSKP 1669
G E L V K +P
Sbjct: 5676 GVDVSECVLTVQTKGGEP 5693
Score = 38.3 bits (85), Expect = 0.059
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
+ +K Q + V A+N+ GE+ S P + P++ + + V+ G+++
Sbjct: 2413 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 2472
Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
V G P P I W N P+ + T D +T + T L K D G Y + A N
Sbjct: 2473 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 2532
Query: 811 EGIAETSAVITV 822
G E + +
Sbjct: 2533 SGKDEHEVDVNI 2544
Score = 37.5 bits (83), Expect = 0.10
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
KS+ D H + KP K V+D E +Y +KA N G + + + A
Sbjct: 625 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 684
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P +++ +K TIK ++ P+P W N + + + + + +
Sbjct: 685 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 744
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I N DSG + NS+G A VT+
Sbjct: 745 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 775
Score = 37.1 bits (82), Expect = 0.14
Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y
Sbjct: 5873 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 5931
Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
+L + + V V + +K PP + + SS P G ST + +
Sbjct: 5932 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 5978
Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
E++ ++ T +W + ++++KT ++++ V + D + KV+K
Sbjct: 5979 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 6033
Query: 1476 ETK 1478
E K
Sbjct: 6034 EKK 6036
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+E + + A N G ++ S N +P + + + +T+K +I V+
Sbjct: 1829 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 1888
Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+
Sbjct: 1889 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 1946
Query: 917 HGARVTIDVEKVT 929
++ + ++K T
Sbjct: 1947 ATVKINV-IDKPT 1958
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
L+N + N +LTC G P P + W +DG + + R
Sbjct: 5604 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 5663
Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
Y A ND G + CV+ +Q K
Sbjct: 5664 AGTYTVTATNDLGVDVSECVLTVQTK 5689
Score = 36.3 bits (80), Expect = 0.24
Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++
Sbjct: 969 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 1028
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
+ + L I D G + KN+ G L +++ P +G
Sbjct: 1029 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 1081
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PP V W+K+ +L+ +Y + I +K +YT+ A N+ GT V L
Sbjct: 5503 PPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFL 5562
Query: 1661 KV--YDKPSKPE 1670
V + +P K E
Sbjct: 5563 NVTRHSEPLKFE 5574
Score = 35.5 bits (78), Expect = 0.42
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVK 845
H +T L PKK + V A + S IT + PT + ++I
Sbjct: 3981 HRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLT---RDILAY 4037
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDY 904
K++ +P P +T+ + ISP++ + + + +T SE+ D G Y
Sbjct: 4038 AGERAKILVPFAASPAPKVTFSKGENKISPTDPRVK-VEYSDFLATLTIEKSELTDGGLY 4096
Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
NS G S R+ + V+K +H++
Sbjct: 4097 FVELENSQGSDSASIRLKV-VDKPASPQHIR 4126
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G T++++ + G P P+ W +K +M + + I D+G FT
Sbjct: 700 GETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMS-SERGKHIMKIENAVRADSGKFTI 758
Query: 584 VAKNAAGFASST-TELIVEAPLSDHG 608
KN++G ST T +V P G
Sbjct: 759 TLKNSSGSCDSTATVTVVGRPTPPKG 784
Score = 34.7 bits (76), Expect = 0.73
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 499 EKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDF 556
++ ++ +++AP I E L G+T++F ++G P P +TW F I +
Sbjct: 1558 DRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQI 1617
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
+ ++ ++ + + + +G +T A N G S T + V++
Sbjct: 1618 E---NEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKS 1660
Score = 33.5 bits (73), Expect = 1.7
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G V G P P ITW F T + S D ++D ++ D GT+
Sbjct: 2174 GQDFSLNIPVSGEPTPTITWTFEGTPV--ESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 2231
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
A+N G ++ ++ +++ P S G
Sbjct: 2232 IKAENENGTDTAEVKVTVLDHPSSPRG 2258
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/104 (20%), Positives = 38/104 (36%), Gaps = 5/104 (4%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+PP + + V G D L + P P I W F+G + D+ + + E
Sbjct: 2157 VPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTK 2216
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
+ + + GTY + A N G + + + + P
Sbjct: 2217 F----HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSP 2256
>AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated
protein 89, isoform e protein.
Length = 5992
Score = 270 bits (663), Expect = 5e-72
Identities = 292/1229 (23%), Positives = 497/1229 (40%), Gaps = 111/1229 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+++ P FV KLR K +G + FEC+VEG+P P++ W ++PS DF++ YD
Sbjct: 642 EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622
A L IR+ P+D G +T +N G S EL V+A P +H
Sbjct: 702 T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
+ P F + DEG ++ + + P P+I W G+ + E +
Sbjct: 746 ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
E + C +L I +V + +G T NR G AS LK++ PP +PL+
Sbjct: 797 ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798
V++ +V+ V G P PT+T+ K +K + + I+I K
Sbjct: 852 DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+G KA+N G AE+ A +TVE+ EE+ P F+ ++ TVK V
Sbjct: 912 HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
NP P +TW+ N + + + N + +T +DS +G C A N+ G+
Sbjct: 972 NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029
Query: 919 AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
AR V + EK FV+ L ET + TV+ E + + WY +E+ D
Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI------PEFIRKLQD 1025
EI + D G I+ + + E S K T+ PEF +
Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVS 1148
Query: 1026 FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKN----KYDFEKRGHIRKLYIRNTS 1080
V++ A+ W +G ++ + D L I +
Sbjct: 1149 LTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTAT 1208
Query: 1081 VHDEGEYSCI--LRDESCTAEVTVVEL--------PPEIITRLQNQKVNKGNKATFEIEL 1130
+ E + I + + + AE T +L P++ L+ Q VNK + A FE+ +
Sbjct: 1209 YYSEVNHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEV-V 1267
Query: 1131 TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+ +WF DG EI + + ++ D + + + C +D S V A +
Sbjct: 1268 VEHATECKWFLDGKEITTAQGVTVSKDDQFE----FRCSIDTTMFGSGTVSVVASNAAGS 1323
Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEI-PDET--LDV--------TWYKKKSVIEDT 1239
VE + L P+ P TD +E+ +T +DV WY+ +++ED
Sbjct: 1324 VETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVIALHSPLYKWYQNGNLLEDG 1383
Query: 1240 EK-FTLISDVKKRTLIIRKCTEDDQ--CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
+ T+ ++ K +LII + + E + + ++S+ +L V P +VD +
Sbjct: 1384 KNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKS 1443
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDA 1355
IK FP P +W +N KI+++ + T +I ++ +L I +
Sbjct: 1444 VTIKETETAEFKATISGFPAPTVKWTINEKIVEESR-TITTIKTEDVYTLKISNAKIEQT 1502
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICWD-EPENTGNSTI 1412
G K+ +N+ G + ++ + P + L ++ + W+ E + T
Sbjct: 1503 GTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTE 1562
Query: 1413 IYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
+ +++ Q + ++ + V +I K S A A N A E
Sbjct: 1563 VSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA-----AGECETS 1617
Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKA 1527
KV + P + +N T E ++ + I G P P VTWY + KKL + K
Sbjct: 1618 AKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKV 1677
Query: 1528 TY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVITISNEDIK 1581
Y + + A N G+V+ + + + +K P T + +D
Sbjct: 1678 KYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDD-- 1735
Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
++ K G++ TA +EG P P V W NG + +T K+ I I + +
Sbjct: 1736 RQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAG 1795
Query: 1642 KYTIEASNTAGTSSVEVTL---KVYDKPS 1667
+ + EA+N G+ +V L KV D P+
Sbjct: 1796 ELSCEATNPVGSKKRDVQLAVKKVGDAPT 1824
Score = 266 bits (652), Expect = 1e-70
Identities = 306/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%)
Query: 460 KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506
+H+ E+KG + L+ D NN YT K +E + +L + FEK T+EE
Sbjct: 2985 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3043
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
+ P+F+E L+ +G TV EC+V PQI +F+ ++ Q Q+ +D
Sbjct: 3044 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3102
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620
L I+ ED G + C A N AG A++ +L VE ++D ++
Sbjct: 3103 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3162
Query: 621 XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ G P F + ++ V E +L+C++ P P I W +G+E+
Sbjct: 3163 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3222
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734
+ + D + L NV + G Y A N G A PI++ ++ K E
Sbjct: 3223 VRAEHKDDGTL---TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3279
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790
P ++P+K +V GE+ +L ++ G P+P++ W KN KP + ++ D T +T
Sbjct: 3280 PDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3339
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+ K+ D Y +A N G + +TV+EP + P F I VKE T
Sbjct: 3340 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 3395
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
K +V+ P + W+++ + + + ++ D LVI + ++ D G+Y+ S
Sbjct: 3396 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 3453
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968
N AG ++ +T+ + +K +G ++L + T KWY + ++
Sbjct: 3454 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 3513
Query: 969 GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018
+I+Q D G + ++ + ++T+ V K ++P
Sbjct: 3514 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 3573
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077
F + L D V + +LEVEI + DV W ++G+ IK K E G+ + +L I
Sbjct: 3574 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 3629
Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ D GEYS +E+ E V PEI++ L V +G ATF +++
Sbjct: 3630 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 3689
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190
V+W+K+G EI + + DG L+I + ++DA +Y S + G++ +A LT
Sbjct: 3690 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 3747
Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
V+ PE + L+P A V++ V WYK I + +
Sbjct: 3748 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 3805
Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302
+ +L I DD +Y V+ DA V+ P IV + + +G
Sbjct: 3806 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 3865
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361
L V+ P+ +W N K I +P D L I + DA YK+
Sbjct: 3866 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 3924
Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416
L + G+ AD +T+ P +P I++ ++ ++I E E +G+ + +
Sbjct: 3925 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 3981
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+E+ ++K I K + L+ SS ++A K+ E
Sbjct: 3982 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4040
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531
KI T KPLK+ + E+ E + P+ V WY++G+++K + +
Sbjct: 4041 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4096
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587
+ YK + N GE E+S + +++ I ED Q G
Sbjct: 4097 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4154
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+ + I+G P +V W ++ N + I + T+ + I + +YT+E
Sbjct: 4155 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4213
Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671
N +G + + +V +KP G
Sbjct: 4214 VINESGKAKSDAKGEVDEKPEIVRG 4238
Score = 248 bits (607), Expect = 3e-65
Identities = 294/1183 (24%), Positives = 489/1183 (41%), Gaps = 110/1183 (9%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G+ + +VEG P+ + W++ T + SQ ++ ++ L I D G +
Sbjct: 3487 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 3545
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
V ST VE+ + +TV P+F K Q
Sbjct: 3546 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 3581
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V +G+ ++LE + P+ D+ W G+EI D + D+ L I + ++
Sbjct: 3582 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 3634
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y+V A N GE I K K P+++ L V+QGE+ + +V G P
Sbjct: 3635 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 3689
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
+ W KN K + TK +GD + +V+D Y + N G A++SA +TV+
Sbjct: 3690 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 3749
Query: 824 EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+ ++ P ++ TVK+ T +V + PV + WY+N + I P+ N
Sbjct: 3750 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 3807
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
DG + L I N + D+ DYK V SN AG + A +T+ + + VK L+ + E +
Sbjct: 3808 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 3864
Query: 943 GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000
GK +L+ +T+ KWY N KEI+ D + +G D K +
Sbjct: 3865 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 3924
Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
+ D++ +T L VK P+ I+ L+D V LE+E + V W ++G
Sbjct: 3925 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 3984
Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109
+ + K ++ K L I ++ V D G+Y + +E+ +A + + + P+I
Sbjct: 3985 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4044
Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166
+ L++Q + +G A F +E +V+W+K+G EI+ ++ I+ D K Q L I
Sbjct: 4045 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4103
Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220
+ DDA Y + G ++ +A LTV++ ++ E +V V+I
Sbjct: 4104 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4163
Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
E DV W + +VI + I D R LII D EYT +++ K+
Sbjct: 4164 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4222
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
+ K EV E P+IV I G D V+ A P +W N + IK H +
Sbjct: 4223 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4280
Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I K L I + + D YK+ L N G D +T++ KPN+L+I
Sbjct: 4281 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4333
Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
++ +EP+ G +I + QE+ + K K ++ +L SS
Sbjct: 4334 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 4392
Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503
+ A V +D E V +K K PT PLK+ E + + L C
Sbjct: 4393 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 4452
Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
G P P+V W +DG L+ T + + Y+ A N+ G
Sbjct: 4453 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGS 4512
Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611
+ C V + + KP I +K + GD+ + G+P P + W+ NG
Sbjct: 4513 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGI 4569
Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
++ D + + + I++++ A N GT
Sbjct: 4570 PIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 4612
Score = 246 bits (603), Expect = 1e-64
Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G+ ILL + P+ + W +KG E V + ++ Y L+I + +
Sbjct: 3484 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 3539
Query: 705 EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y VV + + S V K EK P + L V +G ++L ++ G P
Sbjct: 3540 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 3599
Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+ + W KN +K + G+ + + KD G Y++ A N G E+ A + V
Sbjct: 3600 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 3658
Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+A+P + ++ TVK+ T +V + PV + WY+N + I ++T N
Sbjct: 3659 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 3709
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935
DG + L I N E D+ DYK V SN AG + A +T+ D K V L
Sbjct: 3710 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 3767
Query: 936 KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
+ ++G+T + V KWY N KEI ++ D
Sbjct: 3768 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 3824
Query: 995 GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
K +V D ++S L VK ++ L+D EV + A+L+VE N + ++ W
Sbjct: 3825 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 3884
Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103
++G+ I P + +L I + D EY +L DE SC V +
Sbjct: 3885 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 3944
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160
P+II L++Q V+ G+ EIE + V+W+K+G E+ + I++ ID K
Sbjct: 3945 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4004
Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
L+I ++D G+Y EV G++ + +TVE P I F L + + +A
Sbjct: 4005 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4062
Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271
+VE + V WYK I+ +F + K L+I+ DD Y VL
Sbjct: 4063 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4122
Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+A+S+ +L V+ + KIV + + +G+ + V Q P+ + W+ ++ +I
Sbjct: 4123 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4181
Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
+ ID + L I + DAG Y + + N G A + + +KP
Sbjct: 4182 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4241
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447
+EI ++ + E + + + QEI + K I K + +I + +
Sbjct: 4242 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4299
Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
++ N D+S V+K ++ + LK++ E + +EL G
Sbjct: 4300 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4353
Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
+P+ + WY++G++LK ++ Y+ + ND GEV
Sbjct: 4354 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 4412
Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ VV ++ K S + K GD + I G P PEVIW K+G L+
Sbjct: 4413 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 4472
Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670
D + + T+ +RI+ K+S +Y + A N AG TS +VT+ + ++PSKP+
Sbjct: 4473 KDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPK 4532
Score = 218 bits (533), Expect = 3e-56
Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+E L G+ V + G P+P +TW+ I S D DD +TL
Sbjct: 2114 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2172
Query: 570 IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626
I P+ G C A+N AG S T +I S+ SE +
Sbjct: 2173 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2232
Query: 627 --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ + P P F K K +G + EC + WL G+EI
Sbjct: 2233 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2292
Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733
I V + + + L + NV G YT + N G EA+L ++ + K EK+
Sbjct: 2293 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2352
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791
P+ I L+ + E V+L +V+G P+P ++W +NK + +++ +S +TI
Sbjct: 2353 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 2412
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849
++ +G YT AEN+EG ++T A +TV+ E P+F Q E+++ EK
Sbjct: 2413 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 2463
Query: 850 IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901
+ L V +P P + +Y +E I+ S I D N +VI+ + E D
Sbjct: 2464 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 2522
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960
YK +A+NS G ++ +++T VE F + L+K+ +E + + +E + + +W
Sbjct: 2523 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 2581
Query: 961 YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014
+ + K +S + E+ + E D G + E+S V +
Sbjct: 2582 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 2641
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070
++ P F+R+L EVK + A L V + V W +DG+ ++ + + G
Sbjct: 2642 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 2701
Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124
+ I++ + D G+Y+C + E+ T A VV+ +PPE + +L +V +
Sbjct: 2702 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 2761
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
T +++ + V WFKD + I N H IQ L I D D G YSC
Sbjct: 2762 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 2821
Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232
E G + TA + SI FT +L P + D +TV I +V W+K K
Sbjct: 2822 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 2880
Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
I+++ F TL I++ +D YTC +AK+T + V+ P
Sbjct: 2881 PINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 2940
Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346
V + Y +++G L+V + P+P +W + I +H + ++ S +L
Sbjct: 2941 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3000
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
IK N D G Y + N G
Sbjct: 3001 IKDTNNADFGKYTCQATNKAG 3021
Score = 209 bits (511), Expect = 1e-53
Identities = 292/1248 (23%), Positives = 486/1248 (38%), Gaps = 138/1248 (11%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP+FV+ L+P G + +VEG P P++ WF+ I + +
Sbjct: 2934 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 2993
Query: 564 NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
N + TLVI++ D G +TC A N AG E + E + + E
Sbjct: 2994 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3041
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
E + P F + K + EG ++LEC++ P I + + + +++ +
Sbjct: 3042 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3094
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
+ D ++ L I N KK G Y AVN G+A+ LKI+ K V +
Sbjct: 3095 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3151
Query: 743 SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781
+ + Q E+V +L + V + I CK +P +
Sbjct: 3152 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3211
Query: 782 SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824
+G ++ + KD+G TL +AEN G A T ++T+E
Sbjct: 3212 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEG 3271
Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883
+ + E P F+ + V T L +++ P PS+ WY+N E + PS+ + +N
Sbjct: 3272 APKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3331
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940
D L +TN + D +Y+C ASN G +T+ + +V F K L + +
Sbjct: 3332 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 3389
Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
+E +T EC+ S T KW+ + + H E +G D G
Sbjct: 3390 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 3448
Query: 998 KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052
+ + D + V +P K L D V + +L VE+ + V W +
Sbjct: 3449 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 3508
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106
E + + + KL I + + D G Y +L +S + E VTV +
Sbjct: 3509 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 3568
Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P L +Q V KG E+E+ V+W+K+G EI+ ++ + K +L
Sbjct: 3569 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 3626
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217
I D D GEYS N A + +N + + PE + LVP A
Sbjct: 3627 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 3682
Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273
V++ V WYK I D + T + +L I +D +Y V+ DA
Sbjct: 3683 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 3740
Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
S+ L V++ + P+IV +K+G T V + P +W N K I
Sbjct: 3741 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 3799
Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
K K + D S SL I + D YK+ + N+ G AD +T+ PG
Sbjct: 3800 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 3853
Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443
+ ++ + + + E I + +EI ++ K Q I +
Sbjct: 3854 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 3913
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+ + ++ +E D + + + + P + K L++ I+L
Sbjct: 3914 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 3969
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
G P+ V WY++GK+L A A +N+ YK N+
Sbjct: 3970 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4028
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G +S + ++ P IT + +K + E +V P V WYKNG +++ +
Sbjct: 4029 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4085
Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
+ I K T + IK R + Y I NTAG SS ++T+K
Sbjct: 4086 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4133
Score = 202 bits (494), Expect = 2e-51
Identities = 265/1127 (23%), Positives = 450/1127 (39%), Gaps = 106/1127 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G +L+ P+ +I W G+EI P + + D L I +
Sbjct: 3862 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 3917
Query: 705 EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
Y VV + +G A L +K KEP ++I+ L+ +V G + L + G+P+
Sbjct: 3918 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 3976
Query: 764 PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
T+ W KN K + K + + D + + V+D G Y ++ N G A +S
Sbjct: 3977 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4035
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876
ITVE P +P + Q IT E V N P I WY+N + I P S
Sbjct: 4036 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4086
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
I + +LVI N + D+ YK V N+AG++ A++T+ K K + K
Sbjct: 4087 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4144
Query: 937 SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991
E + +G ++ E + +W + IS + I + +
Sbjct: 4145 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4204
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D G V ++ K + PE +R L++ E+ E D + +VE+++ V
Sbjct: 4205 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4264
Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105
W ++ + IKP + + +K G + +L I + D +Y +L + + C + + +
Sbjct: 4265 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4323
Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159
P +I+ L++ V + ++++ +++W+K+G E++ + +
Sbjct: 4324 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 4383
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214
+ L I D G Y +GN K +++ V+ + F+ +T+
Sbjct: 4384 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 4443
Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267
LT++ I E +V W K V++ ++ T+ ++ TL IR + D +Y
Sbjct: 4444 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYR 4503
Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ +T+ KV V E PK V + G V + P+P +
Sbjct: 4504 VTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ 4563
Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
W +N IK + T + + LTI+ V D G K +N G D +
Sbjct: 4564 WFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 4622
Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437
G + L WD G+ I V+ EW K I T
Sbjct: 4623 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 4682
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480
T I+N + + R + E DI +ET Y+V ++E K +
Sbjct: 4683 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 4741
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535
+P + PL++ T + I L+C +P+ V WY+DG L+ T YE
Sbjct: 4742 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 4801
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587
Y+C+A N HG + TSC V ++ ++ V E K V G
Sbjct: 4802 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 4861
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646
D + + + G P PE+ WY+NG L N I T+ + + + + E S Y E
Sbjct: 4862 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 4921
Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685
A N T T+ V++ L +KP EG P + E+S SV++
Sbjct: 4922 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 4968
Score = 177 bits (430), Expect = 9e-44
Identities = 287/1251 (22%), Positives = 485/1251 (38%), Gaps = 155/1251 (12%)
Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
V+ L P G + + P+ +I W++ I PS Q D DN LVI +
Sbjct: 3854 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 3912
Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
+DA + V + G + D +TV L
Sbjct: 3913 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 3946
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691
P K + Q V GS I LE P+ + W G+E+ ++ I+ D + Y
Sbjct: 3947 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4005
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750
VL+I + G Y V N G A+ + + EP ++PLK + +GE
Sbjct: 4006 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4058
Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ S + PR + W KN KP + DT ++K D Y +
Sbjct: 4059 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4117
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866
EN+ G AE+SA +TV++ + I + E V KG K+V V P + W
Sbjct: 4118 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4172
Query: 867 YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
R+ +IS + I + D L+I + D + D+G+Y N +GK+ A+ +D
Sbjct: 4173 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4230
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984
EK V+ L+ + E EG + + + S V KWY N +EI H E + G
Sbjct: 4231 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4289
Query: 985 XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
D G V+ D ++S L VVK + + + L+D +V+E L+V
Sbjct: 4290 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4349
Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095
++ + W ++G+ +KP + + FE++ + L I ++ D G Y +L D+
Sbjct: 4350 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 4409
Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143
+VV + ++ L++ +V +G+ T + + G+ V W KDG
Sbjct: 4410 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 4468
Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193
+Q + I ++ +DG L+I D G+Y N S C +T E+
Sbjct: 4469 VVLQKDDRITMRVALDGTAT-LRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQ 4527
Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244
PS F + L +P + + + V +P TL W+ I+ ++ TL
Sbjct: 4528 PSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ--WFLNGIPIKFDDRITLDDMADG 4585
Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
I DV++ KC E+ E C + + +PP+ +
Sbjct: 4586 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 4645
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354
RI G + + A P EW + K I+ HT + ++D + + I E +D
Sbjct: 4646 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 4704
Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
G+Y N G A+ + V IL+ + + + D+ N G
Sbjct: 4705 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 4761
Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458
+ V+ + W + ++TSIQ L N S +R A N
Sbjct: 4762 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 4821
Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
+ S + +E K + P K L ++ + + L C G P P++ WY
Sbjct: 4822 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 4881
Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
R+G+ L+ T + Y+C A N HG+ +T +Q
Sbjct: 4882 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 4941
Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+KP ++ +S+ + + + E VT G+P P V W K+G L
Sbjct: 4942 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 4997
Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
D + + + V +RIK Y A+N G+++ + +++ D
Sbjct: 4998 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5048
Score = 176 bits (429), Expect = 1e-43
Identities = 260/1229 (21%), Positives = 496/1229 (40%), Gaps = 133/1229 (10%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VAT 567
AP+F + L+ + ++ E +V G P + WF+ + + +M + + V T
Sbjct: 2548 APVFEQGLKKTSVKEKEEIKMEVKVGG-SAPDVEWFKDDKPVSEDGNHEMKKNPETGVFT 2606
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
LV+++ DAG +T A N AG T E EA ++
Sbjct: 2607 LVVKQAATTDAGKYTAKASNPAG----TAESSAEAEVTQS-------------------- 2642
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
LE PTF ++ V L + +P+P + WL G+ + D + +A
Sbjct: 2643 -LE--KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEG 2699
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
Y +K ++ G Y A N GEA + PP+ +E L + V+
Sbjct: 2700 SGSYSITIKDARLE--DSGKYACRATNPAGEAKTEANFAV-VKNLVPPEFVEKLSPLEVK 2756
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGV 802
+ ES LS +VVG P P++ W K++ P+ + ++ + S+TI ++ D G+
Sbjct: 2757 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQ-GDVGI 2815
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y+ +A N G A T+A + ++ PP F + + + V+E+ T+ L V PVP
Sbjct: 2816 YSCRARNEAGEALTTANFGIIR----DSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVP 2871
Query: 863 SITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
++ W+++++ I+ S ++ + L I E D G Y C A+N AG++ A
Sbjct: 2872 NVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGE-DVGVYTCKATNEAGEAKTTAN 2930
Query: 921 VTI--DVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ + ++E FV+ L K YE E+GK +++ + KW+ + I+ +D++ +I
Sbjct: 2931 MAVQEEIEAPLFVQGL-KPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIA-IDNQHVI 2988
Query: 977 Q---EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
+ E D G C ++ V + IP++ + Q E +V
Sbjct: 2989 EKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAE----EV 3044
Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
L +E ET V E D +++ K NK H + + +N + G++ +
Sbjct: 3045 KPLFIEPLKETFAV--EGDTVVLECKVNK-----ESHPQIKFFKNDQPVEIGQHMQLEVL 3097
Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
E ++T+ E + + + VN KA +L +IQF+ ++
Sbjct: 3098 EDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADL--------------KIQFAAKVE 3143
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
+ + +L ++ G++ VG++ + T + F + L V
Sbjct: 3144 EHVTDESGQL-------EEIGQFET-VGDTASSKTDT-GRGAPEF-VELLRSCTVTEKQQ 3193
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL 1271
A L ++ E + W K+ +E + + D TL T+ D EY C
Sbjct: 3194 AILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAE 3253
Query: 1272 DAKSTTKLKVEVV---EFPPKI----VDYEREYR---IKRGSDVTLLVDYQAFPQPNDEW 1321
+ + + ++ E PKI D+ + + + G L P+P+ +W
Sbjct: 3254 NEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKW 3313
Query: 1322 IVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADVEMNVTIL 1378
N + +K K ++D + LT+ + D Y+ N G +DV + V
Sbjct: 3314 YKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEP 3373
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQ 1437
+ +P + I E + +G + + + + + + ++ TQ
Sbjct: 3374 AQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQ 3433
Query: 1438 TS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTE 1494
I++ KT+ +R N+ ++++ + T + S T ++K L ++
Sbjct: 3434 RLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKGLTDVNVT 3485
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYK 1549
I L+ G P+ V WY+ + + +++ T E+ Y+
Sbjct: 3486 QGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYR 3544
Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIEGIPPPEV 1604
+ D VE+S V + K IS K Q G ++ IEG P +V
Sbjct: 3545 VVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEG-KPKDV 3602
Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYKNG+++++ K ++ + + I + + +Y++ A+N AG + + V
Sbjct: 3603 KWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSA 3660
Query: 1665 KPSKPEG--PVIMREISRESVTIEWKPPL 1691
KP G P +++ + ++ K P+
Sbjct: 3661 KPEIVSGLVPTTVKQGETATFNVKVKGPV 3689
Score = 171 bits (417), Expect = 4e-42
Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%)
Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563
MAP F+ K++ G + FEC V W + I+ ++ +
Sbjct: 2245 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2304
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
LV+ V PEDAG +TC+ +N AG + L V L +
Sbjct: 2305 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2353
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
P F + + ++LEC+++ P+P ++WL + I + S+
Sbjct: 2354 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 2400
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
+ES + + IT+ + +G YT +A N EG + L T + E P + L++
Sbjct: 2401 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 2455
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792
+ GE ++LS V G+P+P + + ++ K + TK +TH ++
Sbjct: 2456 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 2514
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+D Y A NS G A +++ IT + E P+F ++ +VKEK IK+
Sbjct: 2515 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 2568
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911
+V P + W+++++ +S + E + ++ + D+G Y ASN
Sbjct: 2569 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 2627
Query: 912 AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
AG +SS A VT +EK TFV+ L + E T+ + + S +W + + +
Sbjct: 2628 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 2687
Query: 969 GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020
I ++ D G C + + + VVK + PEF+
Sbjct: 2688 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 2747
Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077
KL EVKEK+ L V+ + + V W +D I N + +K+ + L I
Sbjct: 2748 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 2806
Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131
+ D G YSC R+E+ TA ++ +PPE +L+ +V + + T ++++T
Sbjct: 2807 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 2864
Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182
G + V WFKD I N HI +G L I +D G Y+C E G
Sbjct: 2865 VIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 2924
Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237
+K TA + V+E + F L + V A L V + + +V W+K I+
Sbjct: 2925 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 2983
Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286
+ + TL+I+ D +YTC + K T +LK+ F
Sbjct: 2984 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3043
Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344
P ++ +E G V L P ++ N + ++ +H + + + +
Sbjct: 3044 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3103
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
LTI+ + D G Y+ N G A+ ++ I
Sbjct: 3104 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3136
Score = 171 bits (415), Expect = 6e-42
Identities = 215/924 (23%), Positives = 354/924 (38%), Gaps = 76/924 (8%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G T++ + G P P ++W+ ++ SQ+ ++ + + T+ I+++ + +G
Sbjct: 2031 EGDTLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKI-HSEKGTYTVTIKDITCDYSGQVV 2089
Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
C A N G A+S L+V G ++ + T KP
Sbjct: 2090 CEAINEYGKATSEATLLV----LPRGEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSL 2145
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDM-HMYCSVLKIT 698
+ +I L L I D PD ++ I E+D + C+ IT
Sbjct: 2146 TWYINNKEI-LNSDLYTIVTDDKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMIT 2204
Query: 699 NVK-KFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
F E A G + SL + P+ I +K ++G S
Sbjct: 2205 YTSDMFSESESEAQAEEFVGDDLTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSA 2264
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALP-------TKSDGDTHSITILKPKKVKDEGVYTL 805
+ V W K+ K ++ + T +G +L +D G YT
Sbjct: 2265 VFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTC 2324
Query: 806 KAENSEGIAETSAVITVEEPTEENAE--PPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
EN+ G A +TV E E+ +E P FI Q+ T K + L +V P P
Sbjct: 2325 IVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPK 2384
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEID-SGDYKCVASNSAGKSSHGARVT 922
++W +N+ I+ ++ +G +E V T SE+ G Y C+A N+ G S A +T
Sbjct: 2385 VSWLHDNKTITQESITVESVEG--VERV-TITSSELSHQGKYTCIAENTEGTSKTEAFLT 2441
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQT-----------SHTVSTKWYHNKKEISGMD 971
+ E F K LQ E G+ ++L C S + +TK K S
Sbjct: 2442 VQGEAPVFTKELQNK-ELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRI 2499
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETST-MLVVKETIPEFIRKLQDFE 1027
E Q D+ K I + TST + K P F + L+
Sbjct: 2500 AIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKTS 2559
Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH--IRKLYIRNTSVHDEG 1085
VKEK+ +EV++ DV W +D + + N ++ +K + L ++ + D G
Sbjct: 2560 VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGN-HEMKKNPETGVFTLVVKQAATTDAG 2618
Query: 1086 EYSCI------LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG--DALV 1137
+Y+ + S AEVT P + L +V AT + + KG D V
Sbjct: 2619 KYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTV-KGVPDPSV 2677
Query: 1138 RWFKDGSEIQF-SNHIQLTIDGK-KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195
W KDG +Q S+H+ ++G + I D L+D+G+Y+C N A T +
Sbjct: 2678 EWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEA-KTEANFA 2736
Query: 1196 INFTLRLPEFI--LVPANT----DAYLTVE-IPDETLDVTWYKKKS--VIEDTEKFTLIS 1246
+ L PEF+ L P L+V+ + V W+K + I++ +
Sbjct: 2737 VVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQT 2796
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
V +L I + D Y+C +A +T + PP+ R ++
Sbjct: 2797 AVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQ 2856
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKL 1360
+ L V P PN EW + K I + D S +LTIK+ D G+Y
Sbjct: 2857 ETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTC 2916
Query: 1361 RLENNCGHADVEMNVTILDKPSPP 1384
+ N G A N+ + ++ P
Sbjct: 2917 KATNEAGEAKTTANMAVQEEIEAP 2940
Score = 169 bits (412), Expect = 1e-41
Identities = 255/1135 (22%), Positives = 433/1135 (38%), Gaps = 126/1135 (11%)
Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
TF K K Q + EG + P + W G+EI P+ + ++D Y V
Sbjct: 4044 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4101
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
+K N + TY +V N GEA L +K + ++++ L+ +V +G ++
Sbjct: 4102 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4159
Query: 755 SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P + W ++ + A + K D T+ + I+ +KD G YT++ N
Sbjct: 4160 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4217
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
G A++ A V+E E + + I + E V+ PV + WY+N+
Sbjct: 4218 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4269
Query: 871 EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
+ I P+ + G + EL I + D DYK V SN+AG A +T+ V
Sbjct: 4270 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4328
Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984
+ K + EE + V L+ + KWY N +E+ G E + G
Sbjct: 4329 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 4388
Query: 985 XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033
D G + ++ K + S +V K + P F+ L+D EV+E D+
Sbjct: 4389 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 4447
Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
L+ I E +V+WE+DG +++ L IR+ D G+Y +
Sbjct: 4448 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAK 4507
Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142
+E+ +A +VTV E P+ + L+ G+K F +++ ++WF +
Sbjct: 4508 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLN 4567
Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193
G I+F + I L DG L I D +D G C N T E +
Sbjct: 4568 GIPIKFDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 4626
Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244
LR P VP D + V P + T +V W+K IE T +
Sbjct: 4627 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 4685
Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290
+ V I I E D Y CV ++ A++ +VE++E + PKI
Sbjct: 4686 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 4745
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349
+ + G + L A P+ + W + ++ T + +A+L I
Sbjct: 4746 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 4805
Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
D G Y+ N G + +V + K + + W + G+
Sbjct: 4806 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 4862
Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455
S + V +W ++N +T +TS +L N S +R A
Sbjct: 4863 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 4922
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509
N + T + +T+ KP L +++ I+L C G+P
Sbjct: 4923 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 4982
Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561
P V W +DG L + ++ + N Y+C+A N++G T
Sbjct: 4983 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5042
Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
S VV Q P T+ D++ G + ++ P PE++WYK+G
Sbjct: 5043 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5100
Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I+ + + + + I Y + A+N +GT+ + T V P
Sbjct: 5101 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5155
Score = 156 bits (379), Expect = 1e-37
Identities = 258/1109 (23%), Positives = 438/1109 (39%), Gaps = 156/1109 (14%)
Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
F++ L+ + +G +F + PR + W++ IKP+ F + D LVI+
Sbjct: 4045 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4103
Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
+DA T+ V +N AG A S+ +L V+ I++G
Sbjct: 4104 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4145
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+ + Q V +G+ ++ E ++ PE D+ WL I N ++ + D Y
Sbjct: 4146 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4195
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
++ ++K G YTV +N G+A K E P+++ L+++ + +G+
Sbjct: 4196 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4249
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
+ +V P + W KN++ +K L K G + ++ D Y +
Sbjct: 4250 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4308
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N+ G ++SA +TV +P ++ +++ V+E ++L +V P I WY+
Sbjct: 4309 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 4362
Query: 869 NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926
N + + P ++ E+ E +T S+ D G Y+ V N G+ G+ V +
Sbjct: 4363 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 4422
Query: 927 K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975
K F+ L K E EEG + L+C + + W + + D +
Sbjct: 4423 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 4481
Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026
+G D+G + K++ S K T+ P+F+ L+
Sbjct: 4482 ALDG-TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 4540
Query: 1027 EVKEKDVAILEVEINSETADVV-WERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
D V++ + W +G IK + D G+ L IR+ D
Sbjct: 4541 AALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYC-LTIRDVREEDF 4599
Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128
G CI ++E+ T E TV E PP L ++++ G+ E
Sbjct: 4600 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 4658
Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
+ A V WFKDG +I+ + H ++ T+DG ++KI + D G Y C E+G
Sbjct: 4659 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 4717
Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
++ A VE P IN L E V L+ ++ V
Sbjct: 4718 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 4774
Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
WYK + D+ + TL I TE+D Y CV +A T V V+
Sbjct: 4775 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 4834
Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334
P + V E E RG TL P P +W N ++++ T
Sbjct: 4835 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 4894
Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386
+ S D S SLT+ + +D GIY+ EN G A V+M + +KP GK
Sbjct: 4895 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 4953
Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437
P ILE+ S+ N+ E + TG N ++ + I+ + EW + + Q
Sbjct: 4954 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5013
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490
I+N + +R A NE + S TT+ + + + T Q P + +
Sbjct: 5014 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5069
Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+ T + ++L C P P++ WY+DG
Sbjct: 5070 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5098
Score = 149 bits (361), Expect = 2e-35
Identities = 173/749 (23%), Positives = 292/749 (38%), Gaps = 93/749 (12%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S E + F+ L+ +G + +C + G P P++ W + +++ M
Sbjct: 4424 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 4483
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
D ATL IR D G + AKN AG A+S ++ V ++ G + +
Sbjct: 4484 DGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTV----TEQGEQPS---------- 4529
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
P F K G ++ +P+P + W G I D+ I++
Sbjct: 4530 ----------KPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITL 4579
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734
+D + YC L I +V++ GT +A N G + G + P
Sbjct: 4580 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 4636
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
P+ PL + G+ + + V NP + W K+ K ++ T+ +K
Sbjct: 4637 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 4696
Query: 794 --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846
P + D GVY A N G AET A VE E EE P ++ TV
Sbjct: 4697 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 4756
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
I+L +V P S+ WY++ + + ++ + + N +E D G Y+C
Sbjct: 4757 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 4816
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956
VA+N+ G + V + V K K ++ + T + G + L+C +
Sbjct: 4817 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 4876
Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007
KWY N + + R +I+ D G+ +C K Q T+
Sbjct: 4877 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 4935
Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055
+ + +T P+FI +L D V +V LE ++ V W +DG +
Sbjct: 4936 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 4995
Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101
I+ + ++ E + +L I+N +VHDEG Y C+ +E+ +A V
Sbjct: 4996 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5055
Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158
PP ++ + + +G E ++ + W+KDG+ + S+ IQ+++ DG
Sbjct: 5056 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5115
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
L I C DD G Y N TA
Sbjct: 5116 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5143
Score = 147 bits (355), Expect = 1e-34
Identities = 229/1083 (21%), Positives = 415/1083 (38%), Gaps = 90/1083 (8%)
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P PDI W ++ DE + + D + I V+ G YT +A N
Sbjct: 570 KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626
Query: 716 EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
G+AS ++ EKE PP + L+ ++G+ + +V G P P + W +++
Sbjct: 627 YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686
Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
P++ + DG T + I + + D GVYT+K +N G E+ A + V+ ++N
Sbjct: 687 PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
P F + + E ++ + +T +P P I W+ N + +S SE + + L
Sbjct: 746 VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948
I +V D G C SN G +S R+ + V TF K L+ +E TV+
Sbjct: 806 TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863
Query: 949 ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
E S T K+ +G + EI+ +G G I +++
Sbjct: 864 EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923
Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
E+ L V++ + P F++ ++D VK + A+ E + + +V W +G
Sbjct: 924 HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104
+ E H KL I S G C + R E+ V + +
Sbjct: 984 HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+
Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101
Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLT 1217
I + ++DAGE NS + A LTV++ F LR P + V ++A +
Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLR-PVSLTVEKGSEAVFS 1160
Query: 1218 VE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT-----LIIRKCTEDDQCEYTCV 1269
IP T + W + D ++ ++ + L I T + + +
Sbjct: 1161 AHAFGIPLPTYE--WSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTI 1218
Query: 1270 LLDAKST-----TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WI 1322
+ A++T T ++ + P R+ +++ + T L ++ + E W
Sbjct: 1219 SVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQT-VNKTDLAHFEVVVEHATECKWF 1277
Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
++ K I + S D + +G + N G + + + +L+ P
Sbjct: 1278 LDGKEITTAQGVTVSKDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPK 1337
Query: 1383 PPGKPNILE--IDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQT 1438
KP + D + + + +Y + + D +++KN + ++
Sbjct: 1338 ETKKPEFTDKLRDMEVTKGDTVQMDVIALHSPLYKWYQNGNLLEDGKNGVTIKN-EENKS 1396
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S+ S + A NEV S++S ++ +P V K++T + E
Sbjct: 1397 SLIIPNAQDSGKITVEASNEVGSSESSA-----QLTVNPPSTTPIVVDGPKSVTIKETET 1451
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFN 1554
E G P P V W + K ++ ++ E+ K A N
Sbjct: 1452 AEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQN 1511
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE-----WLVTAVIEG-IPPPEVIWYK 1608
G + S ++ +P + + KV DE W ++G P EV W
Sbjct: 1512 SAG--QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRW--NLELDGPSPGTEVSWLL 1567
Query: 1609 NGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
NG L ++D + + T + I E K S T +A N AG + V
Sbjct: 1568 NGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNK 1627
Query: 1668 KPE 1670
KPE
Sbjct: 1628 KPE 1630
Score = 143 bits (347), Expect = 1e-33
Identities = 214/1008 (21%), Positives = 387/1008 (38%), Gaps = 76/1008 (7%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
Q S + +V G P P ITW K++ + + SD D + P +V D G YT
Sbjct: 561 QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N G A TSA V + E+ A PP F+ + ++ KE I V P P +
Sbjct: 621 CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
W +++ + PS +DG+ +L I + + D+G Y N G A + +
Sbjct: 680 VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738
Query: 924 -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
D +K Q + E +EG+ V + + + + W+ N K +S + + I
Sbjct: 739 ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798
Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031
E G++ C ++ S + V P F + L+D V+EK
Sbjct: 799 EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858
Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088
+ EV+++ + + G+ +K + + ++ I NTS+ HD GE
Sbjct: 859 STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917
Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137
++E TAE +TV + P + +++Q V G A FE + + V
Sbjct: 918 AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977
Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
WF +G ++ Q S +++ KL I AG C VG + A L V
Sbjct: 978 TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035
Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
P + P+F+ + + D + E+ E VTWY K ++ +++ +
Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301
+ I+ +D E V +++ + KL V+ F P+ +++
Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKK----CKHTKPSIDSKSASLTIKKVENTDAGI 1357
GS+ P P EW VN + ++ + T+ AS+ + +
Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEV 1213
Query: 1358 YKLRL----ENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNSTI 1412
L + EN G + +TI K P P L++ + + ++T
Sbjct: 1214 NHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATE 1273
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
+ ++ +EI T + ++V Q + + + +V + + + ET K
Sbjct: 1274 CKWFLDGKEITTAQGVTVSK--DDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELK 1331
Query: 1473 VIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY 1529
V++ K + P L+++ + +++ I + P WY++G L+ K T
Sbjct: 1332 VLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLEDGKNGVTI 1389
Query: 1530 ENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHK 1585
+N + A N+ G E+S + + P++ + + K
Sbjct: 1390 KNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKET 1449
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
E+ T I G P P V W N +E + E ++I K + +
Sbjct: 1450 ETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKV 1507
Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692
A N+AG S + LKV P+ + +++ E + W LD
Sbjct: 1508 TAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 1555
Score = 143 bits (346), Expect = 1e-33
Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+ + AP L K G ++ C+V+ PR + W++ ++ + Y++D
Sbjct: 4737 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 4796
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
ATL I + ED G + CVA NA G +++ + V+ P + E
Sbjct: 4797 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 4843
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
G P F+K + D G L+C + P P+I W G+ +
Sbjct: 4844 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 4894
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733
IE+ CS L + EG Y A N G+A +L K K E +
Sbjct: 4895 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 4953
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
PP+ I L M V G + L +V G P P++ W K+ P+ ++
Sbjct: 4954 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5013
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845
+ +K V DEG Y A N G A T + + +++ ++PP F + ++
Sbjct: 5014 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5073
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
E +KL +V +P+P + WY++ I++PS+ I + + + ++ D G Y+
Sbjct: 5074 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5133
Query: 906 CVASNSAGKSSHGARVTI 923
+A+N +G + T+
Sbjct: 5134 VIATNPSGTAQDKGTATV 5151
Score = 139 bits (337), Expect = 2e-32
Identities = 180/762 (23%), Positives = 288/762 (37%), Gaps = 105/762 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F L + P G + EC V+ P ++ WF+ I+ + ++ D +
Sbjct: 4637 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 4696
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I D G + CVA N G A T+ + + +H E +
Sbjct: 4697 IIPFEESDIGVYMCVAVNELGQAE--TQATYQVEILEHVEE------------EKRREYA 4742
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
I P K V+ G I L C++ AIP + W G + D S+ E D
Sbjct: 4743 PKINPPLEDKT----VNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG- 4797
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQVIEPLKS 743
+ L I + + G Y VA N G + + +K E E P + L
Sbjct: 4798 --TATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVD 4855
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKALPTKSDGDTHSITILKPKKVK 798
+ +G+S L V G+P P I W +N N P + T DG S+T+ +
Sbjct: 4856 LWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC-SLTV-NESTMS 4913
Query: 799 DEGVYTLKAENSEGIAETSAVITV-------EEPTEENAEPPLFINRFQEITVKEKGTIK 851
DEG+Y +AEN+ G A+T A V E+P + +PP FI +++V I
Sbjct: 4914 DEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVID 4973
Query: 852 LVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVAS 909
L +VT P PS+ W ++ +I S N + + +L I N D G Y+CVA+
Sbjct: 4974 LECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVH-DEGTYRCVAT 5032
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQT--SHTVST 958
N G ++ + V +D + V + T EG+ + LEC+ S
Sbjct: 5033 NENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEM 5092
Query: 959 KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVV 1012
WY + ++ D +I + D G+ + I + Q+ T V
Sbjct: 5093 VWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVK 5152
Query: 1013 K------------------ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
K P+ + L++ + EK L + + + + W +DG
Sbjct: 5153 KLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDG 5212
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVTVVELPP 1107
E + P E + +L + + + D G Y C+ + SC V + P
Sbjct: 5213 ERVFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKP 5272
Query: 1108 EII-------------TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152
I T L ++ G+ TFE L G+ ++W KDG E+ I
Sbjct: 5273 RDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFEC-LPFGNPFPSIKWLKDGLELFSDEKI 5331
Query: 1153 QL--TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
++ DG Q+L + D G + C N TA E
Sbjct: 5332 KMEAAADG-TQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 5372
Score = 135 bits (327), Expect = 3e-31
Identities = 178/787 (22%), Positives = 309/787 (39%), Gaps = 50/787 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ K + V +G + ++ ++A+ P W G ++ D V I+++ + S
Sbjct: 1342 PEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGN-LLEDGKNGVTIKNEENK--S 1396
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I N + G TV A N G + L + P V++ KS+ +++ E+
Sbjct: 1397 SLIIPNAQ--DSGKITVEASNEVGSSESSAQLTVNP-PSTTPIVVDGPKSVTIKETETAE 1453
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK--AENSE 811
A + G P PT+ W N K V+ T + T + LK K E T+K A+NS
Sbjct: 1454 FKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSA 1513
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITWYRNN 870
G A + V E N + P F ++ + E ++ + +P ++W N
Sbjct: 1514 GQDSKQADLKV----EPNVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNG 1569
Query: 871 EIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID--VEK 927
+ ++ S+T+ G+ + I E+ SG A N+AG+ A+VT++ +K
Sbjct: 1570 QPLTKSDTVQVVDHGDGTYHVTIAEAKPEM-SGTLTAKAKNAAGECETSAKVTVNGGNKK 1628
Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREI--IQEGRXXXX 984
FV+ Q T E T + + WY N K++ + ++ + E
Sbjct: 1629 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 1688
Query: 985 XXXXXXXXDVGVIKCIV-----KDQETSTMLVVKET-IPEFIRKLQDFEVKE-KDVAILE 1037
G I+ K Q T+ + V K+T +P+F + D +VKE +DV
Sbjct: 1689 RIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKFTA 1748
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL------ 1091
V W +GE + N +K G + I + GE SC
Sbjct: 1749 NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGE-HTIEISAVTPEQAGELSCEATNPVGS 1807
Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE--IELTKGDALVRWFKDGSEIQFS 1149
+ V V P L+++ + +G + + + K + W KDG EI
Sbjct: 1808 KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSD 1867
Query: 1150 NHIQLT-IDGKKQKLKIYDCDLDDAGEYS----CEVGNSKCTAILTVEE--PSIN--FTL 1200
H ++ + KL I L+D G + E G ++C+A L V + P F
Sbjct: 1868 GHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQS 1927
Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
+ L +T + D T V WY ++ TE + + T+ I T
Sbjct: 1928 DIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTA 1987
Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQP 1317
D + CV + + + P V++E + + G + L P+P
Sbjct: 1988 DMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEP 2047
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W VN K +++ ++ K + + ++TIK + +G N G A E + +
Sbjct: 2048 VVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLV 2107
Query: 1378 LDKPSPP 1384
L + PP
Sbjct: 2108 LPRGEPP 2114
Score = 134 bits (323), Expect = 9e-31
Identities = 227/1107 (20%), Positives = 414/1107 (37%), Gaps = 74/1107 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYC 692
P F +P + V++GS+ + IP P W G ++ E V +
Sbjct: 1140 PEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGA 1199
Query: 693 SVLKITNVKKFQEG---TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
S+L I + E T +VVA N G L I+ + P++ LK V +
Sbjct: 1200 SILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKT 1259
Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ + +VV W + K + T S D + G ++ A
Sbjct: 1260 D--LAHFEVVVEHATECKWFLDGKEITTAQGVTVSKDDQFEFRCSIDTTMFGSGTVSVVA 1317
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N+ G ET + V E +E +P F ++ +++ V + T+++ +P+ WY
Sbjct: 1318 SNAAGSVETKTELKVLETPKETKKPE-FTDKLRDMEVTKGDTVQMDVIALHSPL--YKWY 1374
Query: 868 RNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+N ++ + +T + L+I N DSG ASN G S A++T++
Sbjct: 1375 QNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DSGKITVEASNEVGSSESSAQLTVNPP 1431
Query: 927 KVT-FVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXX 983
T V KS +E +T + S + KW N+K + I+
Sbjct: 1432 STTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYT 1491
Query: 984 XXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKETI--PEFIRKLQDFEVKEKDVAILE 1037
G +K ++ Q++ L V+ + P+F +L D E +
Sbjct: 1492 LKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWN 1551
Query: 1038 VEIN--SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
+E++ S +V W +G+ + + + I G + ++ +
Sbjct: 1552 LELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAA 1611
Query: 1096 --C--TAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQF 1148
C +A+VTV PE + QN + F +T K V W+ + ++
Sbjct: 1612 GECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQ 1671
Query: 1149 SNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTL 1200
S +++ + K ++I ++ G E G + TA L V++ + FT
Sbjct: 1672 SEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTT 1731
Query: 1201 RLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
+ + V D T + V W + T+ + T+ I T
Sbjct: 1732 NMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVT 1790
Query: 1260 EDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF- 1314
+ CE T + K +L V+ V P + I G ++TL+
Sbjct: 1791 PEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKNLEDRLITEG-ELTLMDAKLNIV 1849
Query: 1315 -PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
P+P W+ + I H K + S L+I + + D G ++ E+ G A+
Sbjct: 1850 KPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECS 1909
Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPEN-----TGNST-IIYYVVEYQEIDTTE 1426
++ ++ K P KP + D + IN+ + TG+ T + + + Q + TE
Sbjct: 1910 ASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATE 1967
Query: 1427 WISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
+ N T I + + + + + A N+ + S T KV+ ++ E
Sbjct: 1968 DTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA--GEVS-TEGPLKVVAPIPVE---FE 2021
Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545
L + T + ++L + G P+P V+WY +GKKL+ ++ +
Sbjct: 2022 TSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDIT 2081
Query: 1546 XXYK----CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIP 1600
Y C A N++G+ + + + + E + + + G + + V G P
Sbjct: 2082 CDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTGTKVVHKVVFTGDP 2141
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS-HSSKYTIEASNTAGTSSVEVT 1659
P + WY N ++ N Y I T +KTS + I H + +A N AG S
Sbjct: 2142 KPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTAN 2201
Query: 1660 LKVY--DKPSKPEGPVIMREISRESVT 1684
+ Y D S+ E E + +T
Sbjct: 2202 MITYTSDMFSESESEAQAEEFVGDDLT 2228
Score = 133 bits (321), Expect = 2e-30
Identities = 185/819 (22%), Positives = 326/819 (39%), Gaps = 81/819 (9%)
Query: 936 KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989
K + ++G + + EC T V KW + KEI + + EG
Sbjct: 2254 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2313
Query: 990 XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036
D G CIV KD +T+ V++ + PEFI LQD K + +L
Sbjct: 2314 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 2373
Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
E ++ E V W D + I + E + ++ I ++ + +G+Y+CI +
Sbjct: 2374 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 2431
Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143
T++ +TV P LQN++++ G K + KG + K
Sbjct: 2432 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 2490
Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195
++I S+ I + D ++ I +D Y NS TA T VE P
Sbjct: 2491 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 2550
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253
L+ V + + V++ DV W+K K V ED + + TL
Sbjct: 2551 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 2607
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309
++++ D +YT + T + + EV + P V +K TL V
Sbjct: 2608 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 2667
Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P+ EW+ + + ++ H ++ S S S+TIK D+G Y R N G
Sbjct: 2668 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 2727
Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
A E N ++ PP K + LE+ + T + VE+ + DT
Sbjct: 2728 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 2782
Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
I ++ + QT++ +L N + + Y+ + + + TT + +I+++
Sbjct: 2783 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 2840
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534
P + L+ + E ++L G P P V W++D K + AK
Sbjct: 2841 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT 2900
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593
Y C A N+ GE +T+ + +Q++ + + +K + + G +
Sbjct: 2901 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 2960
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651
+EG P PEV W+K+G + D ++ I K + + + IK+ + KYT +A+N A
Sbjct: 2961 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3020
Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686
G LK+ ++K + E + E +E+ +E
Sbjct: 3021 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3059
Score = 130 bits (313), Expect = 1e-29
Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K +++ P F + L G + +C V G P P+I W+R +++ +
Sbjct: 4837 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 4896
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
D +L + E D G + C A+NA G A + V+ L
Sbjct: 4897 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 4942
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ EG PP F + V G+ I LEC++ +P P + W G ++ D
Sbjct: 4943 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5000
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732
+ E+ +Y L+I N EGTY VA N G A+ +++ G
Sbjct: 5001 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5058
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789
+PP+ + + +G+ + L +V +P P + W K+ A+ T SD S+
Sbjct: 5059 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5114
Query: 790 ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832
T+L P V D+G+Y + A N G A+ TV++ P + A +
Sbjct: 5115 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5174
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890
P + + I + EK + +L + + +P P+I W+++ E + P + ++ DG EL
Sbjct: 5175 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5233
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
V+ + + D+G Y+CVA N+ G + V +
Sbjct: 5234 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5265
Score = 127 bits (306), Expect = 1e-28
Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+ + AP +E L P+ + + C+ G P+P I WF+ + P Q+ D
Sbjct: 5170 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5229
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
V LV+ +DAG + CVA+N G S+ T V D
Sbjct: 5230 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5275
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
+ I EG P F+ + G + EC P P I WL G E+ DE I +
Sbjct: 5276 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5335
Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731
+D L +++V EG + VA N G AS L I+ GE
Sbjct: 5336 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 5392
Query: 732 KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782
E P++ L +M + +G V + G P PT+ W K+ + + K +
Sbjct: 5393 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 5452
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834
+ H + I+ DEG Y+L+A N G A+T + + P +A+ PP
Sbjct: 5453 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 5511
Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893
F+ + + V V +P P + W+ N + I P I Q+ G + L+I
Sbjct: 5512 FVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 5571
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ E D+G+Y A NS G +S A + + V + +K
Sbjct: 5572 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 5609
Score = 121 bits (292), Expect = 5e-27
Identities = 224/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
+P+ L D YT E I++ + E P V L P+G
Sbjct: 4199 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4251
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
F+ +V P Q+ W++ IKP+ + L I +D + V NA
Sbjct: 4252 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4310
Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
AG S+ L V P I++G+ ++P+
Sbjct: 4311 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4343
Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
+ L+ ++ IP+ I W G+E+ PD + E L I + KK G Y
Sbjct: 4344 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 4400
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764
VV N +GE V+ +K+ + P + PLK V +G+ + L + G P P
Sbjct: 4401 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 4460
Query: 765 TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
+ W K+ ++ + DG T ++ I KK D G Y + A+N G A +
Sbjct: 4461 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSAKK-SDIGQYRVTAKNEAGSATSDCK 4518
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+TV E E+ ++P F+ + + +V P P++ W+ N I + I
Sbjct: 4519 VTVTEQGEQPSKPK-FVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRI 4577
Query: 880 T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928
T + N L I +V E D G KC+A N G + H D+
Sbjct: 4578 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 4636
Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985
G + +EC + T +W+ + K+I H EI
Sbjct: 4637 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 4696
Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030
D+GV C+ ++ ET V +E P+ L+D V
Sbjct: 4697 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 4756
Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
L ++++ A VVW +DG ++ + +E+ G L I +++ D G Y
Sbjct: 4757 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 4815
Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
C+ + SC+ V V + P L + ++G+ T + +T GD
Sbjct: 4816 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 4874
Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
++W+++G ++ I+ + DG L + + + D G Y CE G +K A
Sbjct: 4875 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 4933
Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233
V E+P ++ + P+FIL ++ L I E V W K
Sbjct: 4934 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 4992
Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283
+ + +F ++ K L I+ T D+ Y CV + +TTK V +
Sbjct: 4993 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5052
Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
PP+ + R G + L A P P W + I+ + S+
Sbjct: 5053 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5112
Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
A+L I D GIY++ N G A + T+ P G
Sbjct: 5113 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5159
Score = 116 bits (278), Expect = 2e-25
Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
EKP +E P F+ +L G+ + EC+V G P P + W + + F+
Sbjct: 4945 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5003
Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ V L I+ D GT+ CVA N G S+TT+ V D G V
Sbjct: 5004 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5058
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
PP F+ K EG + LEC++ A P P++ W G + P
Sbjct: 5059 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5104
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
+ I +++ D + L I + +G Y V+A N G A +K +G +
Sbjct: 5105 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5161
Query: 733 -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778
+ P+++EPL+++ + + +S L + G+P+PTI W K+ + P L
Sbjct: 5162 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5221
Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829
D ++ +D G Y AEN+ G A TS + V +P +
Sbjct: 5222 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5281
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+ P F K ++ NP PSI W ++ + E I + +
Sbjct: 5282 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5341
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944
+I + + + G ++CVA+N G +S A + I+ ++ + L + + E EE K
Sbjct: 5342 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 5397
Score = 102 bits (244), Expect = 3e-21
Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%)
Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144
+ DES E+ P P+ IT++++ K KG+ A FE + TKG +W KDG
Sbjct: 2227 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2285
Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194
EI+ I++ T G + Q+L + + +DAG+Y+C V G C A LTV E
Sbjct: 2286 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2345
Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246
+ PEFI+ T + +E I + V+W + K++ +++ +
Sbjct: 2346 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 2405
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304
V++ T+ + + Q +YTC+ + + T+K + + V P + + G
Sbjct: 2406 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 2463
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356
+ L + PQP+ ++ S+ K + K T S I+ + + I ++ D
Sbjct: 2464 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 2523
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
YK N+ G A +T + +P + + + E + G++ + +
Sbjct: 2524 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 2582
Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
+ + + +K +T ++ T + ++ A A N +++S E +
Sbjct: 2583 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 2641
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527
++ PT + L + NE L+ GVP P V W +DG+ ++T AK
Sbjct: 2642 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 2697
Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586
Y C A N GE +T + + V E + + K
Sbjct: 2698 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 2757
Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644
+ ++ + G P P V W+K+ + D + I T + + I + ++ Y+
Sbjct: 2758 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 2817
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688
A N AG + + PE +R + RE T++ K
Sbjct: 2818 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 2862
Score = 90.6 bits (215), Expect = 1e-17
Identities = 86/357 (24%), Positives = 146/357 (40%), Gaps = 16/357 (4%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G PTF+K + + + EG L++ +L + P+P I WL G EI D + + E D
Sbjct: 1820 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 1879
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQ 748
+ S+L+ K +G T+ A + G A L + G P + + + +
Sbjct: 1880 LKLSILQ---TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTE 1936
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-- 806
G+++ + G+P P + W + V A + + + +K V + +K
Sbjct: 1937 GDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCV 1996
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G T + V P P F + T +E T+KL A + P P ++W
Sbjct: 1997 AYNKAGEVSTEGPLKVVAPI-----PVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSW 2051
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--D 924
Y N + + S+ I + + + I ++ + SG C A N GK++ A + +
Sbjct: 2052 YVNGKKLEESQNIKIHSEKGTYTVTIKDITCDY-SGQVVCEAINEYGKATSEATLLVLPR 2110
Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGR 980
E F++ L K V T S WY N KEI D I+ + +
Sbjct: 2111 GEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDK 2167
Score = 70.9 bits (166), Expect = 9e-12
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
+Y E + + + P+PDI W F+G +I S + L IT K
Sbjct: 5779 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 5838
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y A N G+A I++ + T P I+PL + + + + +V G P
Sbjct: 5839 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 5894
Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
P + W K +P+ + DG I+ +D G+Y+ A N G A TS
Sbjct: 5895 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 5954
Query: 820 ITVEEPTEEN 829
+TVE + N
Sbjct: 5955 VTVEAEGDYN 5964
Score = 60.5 bits (140), Expect = 1e-08
Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531
K+++ ++P L++ TT+ +E + L C G P+PKV+W D K + T E+
Sbjct: 2347 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 2406
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589
Y CIA N G +T + +Q + PV T ++++ K +G++
Sbjct: 2407 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 2463
Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641
+++ ++G P P V +Y K K+ + I + + R I ++ +
Sbjct: 2464 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 2523
Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y A+N+ G TS+ ++T KV + P +G +E + +E K +E
Sbjct: 2524 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 2582
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
K E N+ K + + V T +++ + A NP G +E+
Sbjct: 2583 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 2633
Score = 57.6 bits (133), Expect = 9e-08
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565
S+ P F +KLRP + T+ + V G P P + WF+ I D+
Sbjct: 2839 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGH 2898
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608
TL I++ ED G +TC A N AG A +T + V EAPL G
Sbjct: 2899 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 2945
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
++P + +PL+NI + L C F G P+P + W++DG+++ + +
Sbjct: 5173 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5232
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581
Y+C+A N +G TSC V + +KP I S + K
Sbjct: 5233 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5292
Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639
++ K GD + G P P + W K+G +L +D++ + + T + + ++
Sbjct: 5293 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5352
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ A+N GT+S + L +
Sbjct: 5353 EGYFRCVATNEHGTASTKAELVI 5375
Score = 55.6 bits (128), Expect = 4e-07
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
D YT +Q + K +F + ++ +AP F + +G V+F+ + G
Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773
Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
P P+I WF + S+ + + +D + L I++V G TC N G AS
Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832
Query: 596 TELIVEAP 603
L V P
Sbjct: 833 GRLKVRVP 840
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
++P PL +P + + C+ G P P + W +DG +L + +A +
Sbjct: 5283 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5342
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
++C+A N+HG T +G + P + E+ K + +
Sbjct: 5343 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 5402
Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
G E V +I GIP P V WYK+G ++ D K T + + I
Sbjct: 5403 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 5462
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+Y++EA+N G++ E +L +
Sbjct: 5463 NASPDDEGEYSLEATNKLGSAKTEGSLNI 5491
Score = 53.6 bits (123), Expect = 1e-06
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
+ +++ + V G P P I W + P + G + + + ++ G
Sbjct: 5783 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 5842
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
Y A+N G A+ + I V+ T N PL +N+ T +++ RV P
Sbjct: 5843 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 5895
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
P + W + I S I DG + +I N DSG Y CVA N AG+++ V
Sbjct: 5896 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 5955
Query: 922 TIDVE 926
T++ E
Sbjct: 5956 TVEAE 5960
Score = 53.2 bits (122), Expect = 2e-06
Identities = 26/93 (27%), Positives = 49/93 (52%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+
Sbjct: 5867 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 5926
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
I + D+G ++CVA N AG A+++ + VEA
Sbjct: 5927 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 5959
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559
Q AP+F ++L+ K G + C V+G P+P + + F +T ++ S +
Sbjct: 2443 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 2502
Query: 560 YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612
+D N +VI ++ ED ++ +A N+ G A+ST+++ VEAP+ + G + T
Sbjct: 2503 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 2558
Score = 51.6 bits (118), Expect = 6e-06
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
L V E + + AP F+ L+ K T V EC+V G P+P+++W I +Q
Sbjct: 2339 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 2396
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604
+ + V + I G +TC+A+N G + + L V EAP+
Sbjct: 2397 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 2448
Score = 50.0 bits (114), Expect = 2e-05
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
S+ + +V GYP P ITW++ + + Y D+D + I V D G +TC+
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 585 AKNAAGFASST 595
A N G AS++
Sbjct: 623 ATNEYGQASTS 633
Score = 48.4 bits (110), Expect = 6e-05
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F + P + +G T++ + + G P P + W+ T ++ ++D ++ + + V T+
Sbjct: 1923 PAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEI-SNANGVYTMK 1981
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
I V + G CVA N AG S+ L V AP+
Sbjct: 1982 IHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPI 2016
Score = 48.0 bits (109), Expect = 7e-05
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
+E P R L + + E +V + V T V W +DG+ I P + F
Sbjct: 5394 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 5453
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
I L I N S DEGEYS ++ +A+ + ++ PP +
Sbjct: 5454 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 5513
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
+L+N+ V F+ + A V WF +G +I I++ + G L I D
Sbjct: 5514 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 5573
Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
L+DAGEY G++ +A+L V P ++ E + P T+ Y
Sbjct: 5574 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 5624
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T S PI V+ + + T +F+ + G+P P + W I++ S+
Sbjct: 1427 TVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKT 1486
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
+D V TL I E GT A+N+AG S +L VE
Sbjct: 1487 ED-VYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVE 1525
Score = 45.2 bits (102), Expect = 5e-04
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
+L V E P +++ P F +KLR G TVQ + V P W++ +++
Sbjct: 1329 ELKVLETP---KETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGNLLEDG 1383
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
++ +++N ++L+I +D+G T A N G + S+ +L V P
Sbjct: 1384 KNGVTIKNEENKSSLIIPNA--QDSGKITVEASNEVGSSESSAQLTVNPP 1431
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437
P+PP + P I E+ + + W + + YV+E +E+ +W ++ NI +
Sbjct: 5635 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 5694
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
++NL+ SY+FR A N ISD S
Sbjct: 5695 CKVRNLELGKSYQFRVRAENIYGISDPS 5722
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K T + P FV+ + T +V+F V G P P +TW+ + S++ ++
Sbjct: 1619 KVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVK 1678
Query: 560 YDDDNVATLV-IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
Y + T + I++ E GT A+N +G +T +L V+
Sbjct: 1679 YVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVD 1721
Score = 39.9 bits (89), Expect = 0.019
Identities = 45/203 (22%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXX 1534
P + + L N++ +E+ G+P P V WY+DG+++ K T E
Sbjct: 5398 PRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIH 5457
Query: 1535 XXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE------------DIK 1581
Y A N G +T + I + I ++E +K
Sbjct: 5458 HLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 5517
Query: 1582 QKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSH 1639
KH + ++ G P PEV W+ NG K+ I + S + I +
Sbjct: 5518 NKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLED 5577
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ +Y A N+ G++S L V
Sbjct: 5578 AGEYVATAKNSHGSASSSAVLDV 5600
Score = 39.1 bits (87), Expect = 0.034
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++
Sbjct: 5762 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 5821
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
Y + TL I E+ G + C AKN G A
Sbjct: 5822 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 5855
Score = 37.9 bits (84), Expect = 0.078
Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGY-PRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
AP F + L + +G + ++ P+P+ITW + I +++ ++D
Sbjct: 1822 APTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLK 1881
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
L I + ED G T A++ G A + L
Sbjct: 1882 LSILQTKLEDKGRITIKAESEFGVAECSASL 1912
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472
E R A+ Y + + EAI L +G+ + +LD N W V+ K GWVP
Sbjct: 61 ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120
Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500
Y + Y Q++ +I+ + + ++
Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146
Score = 35.9 bits (79), Expect = 0.32
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 11/130 (8%)
Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDD----KITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
L + + I EI + PY +++ K+ TPP R + E T +TL
Sbjct: 5598 LDVTVPFLDSIKFNGEIDVT-PYLTEEYGFKKLNTASLPTPPD--RGPFIKEVTGHYLTL 5654
Query: 1885 KWTEPE-SNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA 1942
W + + P Y+IE + + K W+ + + V + + N++ FR+ A
Sbjct: 5655 SWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCK--VRNLELGKSYQFRVRA 5712
Query: 1943 ENTVGVSLPT 1952
EN G+S P+
Sbjct: 5713 ENIYGISDPS 5722
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1786 ITWFPSEKNGGS-PIIDYKVEIKQ-EGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYAR 1842
++W P+++ P + Y +EI++ K+W +++ L + +YQFR+ A
Sbjct: 5654 LSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAE 5713
Query: 1843 NEIGTSLP 1850
N G S P
Sbjct: 5714 NIYGISDP 5721
>AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated
protein 89, isoform f protein.
Length = 7441
Score = 270 bits (663), Expect = 5e-72
Identities = 292/1229 (23%), Positives = 497/1229 (40%), Gaps = 111/1229 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+++ P FV KLR K +G + FEC+VEG+P P++ W ++PS DF++ YD
Sbjct: 642 EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622
A L IR+ P+D G +T +N G S EL V+A P +H
Sbjct: 702 T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
+ P F + DEG ++ + + P P+I W G+ + E +
Sbjct: 746 ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
E + C +L I +V + +G T NR G AS LK++ PP +PL+
Sbjct: 797 ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798
V++ +V+ V G P PT+T+ K +K + + I+I K
Sbjct: 852 DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+G KA+N G AE+ A +TVE+ EE+ P F+ ++ TVK V
Sbjct: 912 HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
NP P +TW+ N + + + N + +T +DS +G C A N+ G+
Sbjct: 972 NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029
Query: 919 AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
AR V + EK FV+ L ET + TV+ E + + WY +E+ D
Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI------PEFIRKLQD 1025
EI + D G I+ + + E S K T+ PEF +
Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVS 1148
Query: 1026 FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKN----KYDFEKRGHIRKLYIRNTS 1080
V++ A+ W +G ++ + D L I +
Sbjct: 1149 LTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTAT 1208
Query: 1081 VHDEGEYSCI--LRDESCTAEVTVVEL--------PPEIITRLQNQKVNKGNKATFEIEL 1130
+ E + I + + + AE T +L P++ L+ Q VNK + A FE+ +
Sbjct: 1209 YYSEVNHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEV-V 1267
Query: 1131 TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+ +WF DG EI + + ++ D + + + C +D S V A +
Sbjct: 1268 VEHATECKWFLDGKEITTAQGVTVSKDDQFE----FRCSIDTTMFGSGTVSVVASNAAGS 1323
Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEI-PDET--LDV--------TWYKKKSVIEDT 1239
VE + L P+ P TD +E+ +T +DV WY+ +++ED
Sbjct: 1324 VETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVIALHSPLYKWYQNGNLLEDG 1383
Query: 1240 EK-FTLISDVKKRTLIIRKCTEDDQ--CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
+ T+ ++ K +LII + + E + + ++S+ +L V P +VD +
Sbjct: 1384 KNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKS 1443
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDA 1355
IK FP P +W +N KI+++ + T +I ++ +L I +
Sbjct: 1444 VTIKETETAEFKATISGFPAPTVKWTINEKIVEESR-TITTIKTEDVYTLKISNAKIEQT 1502
Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICWD-EPENTGNSTI 1412
G K+ +N+ G + ++ + P + L ++ + W+ E + T
Sbjct: 1503 GTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTE 1562
Query: 1413 IYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
+ +++ Q + ++ + V +I K S A A N A E
Sbjct: 1563 VSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA-----AGECETS 1617
Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKA 1527
KV + P + +N T E ++ + I G P P VTWY + KKL + K
Sbjct: 1618 AKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKV 1677
Query: 1528 TY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVITISNEDIK 1581
Y + + A N G+V+ + + + +K P T + +D
Sbjct: 1678 KYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDD-- 1735
Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
++ K G++ TA +EG P P V W NG + +T K+ I I + +
Sbjct: 1736 RQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAG 1795
Query: 1642 KYTIEASNTAGTSSVEVTL---KVYDKPS 1667
+ + EA+N G+ +V L KV D P+
Sbjct: 1796 ELSCEATNPVGSKKRDVQLAVKKVGDAPT 1824
Score = 266 bits (652), Expect = 1e-70
Identities = 306/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%)
Query: 460 KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506
+H+ E+KG + L+ D NN YT K +E + +L + FEK T+EE
Sbjct: 2985 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3043
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
+ P+F+E L+ +G TV EC+V PQI +F+ ++ Q Q+ +D
Sbjct: 3044 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3102
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620
L I+ ED G + C A N AG A++ +L VE ++D ++
Sbjct: 3103 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3162
Query: 621 XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ G P F + ++ V E +L+C++ P P I W +G+E+
Sbjct: 3163 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3222
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734
+ + D + L NV + G Y A N G A PI++ ++ K E
Sbjct: 3223 VRAEHKDDGTL---TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3279
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790
P ++P+K +V GE+ +L ++ G P+P++ W KN KP + ++ D T +T
Sbjct: 3280 PDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3339
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+ K+ D Y +A N G + +TV+EP + P F I VKE T
Sbjct: 3340 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 3395
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
K +V+ P + W+++ + + + ++ D LVI + ++ D G+Y+ S
Sbjct: 3396 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 3453
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968
N AG ++ +T+ + +K +G ++L + T KWY + ++
Sbjct: 3454 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 3513
Query: 969 GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018
+I+Q D G + ++ + ++T+ V K ++P
Sbjct: 3514 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 3573
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077
F + L D V + +LEVEI + DV W ++G+ IK K E G+ + +L I
Sbjct: 3574 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 3629
Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ D GEYS +E+ E V PEI++ L V +G ATF +++
Sbjct: 3630 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 3689
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190
V+W+K+G EI + + DG L+I + ++DA +Y S + G++ +A LT
Sbjct: 3690 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 3747
Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
V+ PE + L+P A V++ V WYK I + +
Sbjct: 3748 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 3805
Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302
+ +L I DD +Y V+ DA V+ P IV + + +G
Sbjct: 3806 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 3865
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361
L V+ P+ +W N K I +P D L I + DA YK+
Sbjct: 3866 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 3924
Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416
L + G+ AD +T+ P +P I++ ++ ++I E E +G+ + +
Sbjct: 3925 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 3981
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+E+ ++K I K + L+ SS ++A K+ E
Sbjct: 3982 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4040
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531
KI T KPLK+ + E+ E + P+ V WY++G+++K + +
Sbjct: 4041 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4096
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587
+ YK + N GE E+S + +++ I ED Q G
Sbjct: 4097 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4154
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+ + I+G P +V W ++ N + I + T+ + I + +YT+E
Sbjct: 4155 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4213
Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671
N +G + + +V +KP G
Sbjct: 4214 VINESGKAKSDAKGEVDEKPEIVRG 4238
Score = 248 bits (607), Expect = 3e-65
Identities = 294/1183 (24%), Positives = 489/1183 (41%), Gaps = 110/1183 (9%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G+ + +VEG P+ + W++ T + SQ ++ ++ L I D G +
Sbjct: 3487 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 3545
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
V ST VE+ + +TV P+F K Q
Sbjct: 3546 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 3581
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V +G+ ++LE + P+ D+ W G+EI D + D+ L I + ++
Sbjct: 3582 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 3634
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y+V A N GE I K K P+++ L V+QGE+ + +V G P
Sbjct: 3635 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 3689
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
+ W KN K + TK +GD + +V+D Y + N G A++SA +TV+
Sbjct: 3690 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 3749
Query: 824 EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+ ++ P ++ TVK+ T +V + PV + WY+N + I P+ N
Sbjct: 3750 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 3807
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
DG + L I N + D+ DYK V SN AG + A +T+ + + VK L+ + E +
Sbjct: 3808 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 3864
Query: 943 GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000
GK +L+ +T+ KWY N KEI+ D + +G D K +
Sbjct: 3865 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 3924
Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
+ D++ +T L VK P+ I+ L+D V LE+E + V W ++G
Sbjct: 3925 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 3984
Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109
+ + K ++ K L I ++ V D G+Y + +E+ +A + + + P+I
Sbjct: 3985 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4044
Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166
+ L++Q + +G A F +E +V+W+K+G EI+ ++ I+ D K Q L I
Sbjct: 4045 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4103
Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220
+ DDA Y + G ++ +A LTV++ ++ E +V V+I
Sbjct: 4104 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4163
Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
E DV W + +VI + I D R LII D EYT +++ K+
Sbjct: 4164 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4222
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
+ K EV E P+IV I G D V+ A P +W N + IK H +
Sbjct: 4223 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4280
Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I K L I + + D YK+ L N G D +T++ KPN+L+I
Sbjct: 4281 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4333
Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
++ +EP+ G +I + QE+ + K K ++ +L SS
Sbjct: 4334 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 4392
Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503
+ A V +D E V +K K PT PLK+ E + + L C
Sbjct: 4393 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 4452
Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
G P P+V W +DG L+ T + + Y+ A N+ G
Sbjct: 4453 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGS 4512
Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611
+ C V + + KP I +K + GD+ + G+P P + W+ NG
Sbjct: 4513 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGI 4569
Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
++ D + + + I++++ A N GT
Sbjct: 4570 PIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 4612
Score = 246 bits (603), Expect = 1e-64
Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G+ ILL + P+ + W +KG E V + ++ Y L+I + +
Sbjct: 3484 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 3539
Query: 705 EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y VV + + S V K EK P + L V +G ++L ++ G P
Sbjct: 3540 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 3599
Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+ + W KN +K + G+ + + KD G Y++ A N G E+ A + V
Sbjct: 3600 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 3658
Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+A+P + ++ TVK+ T +V + PV + WY+N + I ++T N
Sbjct: 3659 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 3709
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935
DG + L I N E D+ DYK V SN AG + A +T+ D K V L
Sbjct: 3710 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 3767
Query: 936 KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
+ ++G+T + V KWY N KEI ++ D
Sbjct: 3768 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 3824
Query: 995 GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
K +V D ++S L VK ++ L+D EV + A+L+VE N + ++ W
Sbjct: 3825 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 3884
Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103
++G+ I P + +L I + D EY +L DE SC V +
Sbjct: 3885 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 3944
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160
P+II L++Q V+ G+ EIE + V+W+K+G E+ + I++ ID K
Sbjct: 3945 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4004
Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
L+I ++D G+Y EV G++ + +TVE P I F L + + +A
Sbjct: 4005 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4062
Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271
+VE + V WYK I+ +F + K L+I+ DD Y VL
Sbjct: 4063 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4122
Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+A+S+ +L V+ + KIV + + +G+ + V Q P+ + W+ ++ +I
Sbjct: 4123 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4181
Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
+ ID + L I + DAG Y + + N G A + + +KP
Sbjct: 4182 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4241
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447
+EI ++ + E + + + QEI + K I K + +I + +
Sbjct: 4242 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4299
Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
++ N D+S V+K ++ + LK++ E + +EL G
Sbjct: 4300 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4353
Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
+P+ + WY++G++LK ++ Y+ + ND GEV
Sbjct: 4354 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 4412
Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ VV ++ K S + K GD + I G P PEVIW K+G L+
Sbjct: 4413 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 4472
Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670
D + + T+ +RI+ K+S +Y + A N AG TS +VT+ + ++PSKP+
Sbjct: 4473 KDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPK 4532
Score = 218 bits (533), Expect = 3e-56
Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+E L G+ V + G P+P +TW+ I S D DD +TL
Sbjct: 2114 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2172
Query: 570 IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626
I P+ G C A+N AG S T +I S+ SE +
Sbjct: 2173 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2232
Query: 627 --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ + P P F K K +G + EC + WL G+EI
Sbjct: 2233 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2292
Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733
I V + + + L + NV G YT + N G EA+L ++ + K EK+
Sbjct: 2293 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2352
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791
P+ I L+ + E V+L +V+G P+P ++W +NK + +++ +S +TI
Sbjct: 2353 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 2412
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849
++ +G YT AEN+EG ++T A +TV+ E P+F Q E+++ EK
Sbjct: 2413 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 2463
Query: 850 IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901
+ L V +P P + +Y +E I+ S I D N +VI+ + E D
Sbjct: 2464 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 2522
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960
YK +A+NS G ++ +++T VE F + L+K+ +E + + +E + + +W
Sbjct: 2523 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 2581
Query: 961 YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014
+ + K +S + E+ + E D G + E+S V +
Sbjct: 2582 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 2641
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070
++ P F+R+L EVK + A L V + V W +DG+ ++ + + G
Sbjct: 2642 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 2701
Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124
+ I++ + D G+Y+C + E+ T A VV+ +PPE + +L +V +
Sbjct: 2702 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 2761
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
T +++ + V WFKD + I N H IQ L I D D G YSC
Sbjct: 2762 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 2821
Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232
E G + TA + SI FT +L P + D +TV I +V W+K K
Sbjct: 2822 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 2880
Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
I+++ F TL I++ +D YTC +AK+T + V+ P
Sbjct: 2881 PINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 2940
Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346
V + Y +++G L+V + P+P +W + I +H + ++ S +L
Sbjct: 2941 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3000
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
IK N D G Y + N G
Sbjct: 3001 IKDTNNADFGKYTCQATNKAG 3021
Score = 209 bits (511), Expect = 1e-53
Identities = 292/1248 (23%), Positives = 486/1248 (38%), Gaps = 138/1248 (11%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP+FV+ L+P G + +VEG P P++ WF+ I + +
Sbjct: 2934 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 2993
Query: 564 NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
N + TLVI++ D G +TC A N AG E + E + + E
Sbjct: 2994 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3041
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
E + P F + K + EG ++LEC++ P I + + + +++ +
Sbjct: 3042 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3094
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
+ D ++ L I N KK G Y AVN G+A+ LKI+ K V +
Sbjct: 3095 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3151
Query: 743 SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781
+ + Q E+V +L + V + I CK +P +
Sbjct: 3152 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3211
Query: 782 SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824
+G ++ + KD+G TL +AEN G A T ++T+E
Sbjct: 3212 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEG 3271
Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883
+ + E P F+ + V T L +++ P PS+ WY+N E + PS+ + +N
Sbjct: 3272 APKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3331
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940
D L +TN + D +Y+C ASN G +T+ + +V F K L + +
Sbjct: 3332 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 3389
Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
+E +T EC+ S T KW+ + + H E +G D G
Sbjct: 3390 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 3448
Query: 998 KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052
+ + D + V +P K L D V + +L VE+ + V W +
Sbjct: 3449 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 3508
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106
E + + + KL I + + D G Y +L +S + E VTV +
Sbjct: 3509 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 3568
Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P L +Q V KG E+E+ V+W+K+G EI+ ++ + K +L
Sbjct: 3569 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 3626
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217
I D D GEYS N A + +N + + PE + LVP A
Sbjct: 3627 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 3682
Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273
V++ V WYK I D + T + +L I +D +Y V+ DA
Sbjct: 3683 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 3740
Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
S+ L V++ + P+IV +K+G T V + P +W N K I
Sbjct: 3741 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 3799
Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
K K + D S SL I + D YK+ + N+ G AD +T+ PG
Sbjct: 3800 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 3853
Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443
+ ++ + + + E I + +EI ++ K Q I +
Sbjct: 3854 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 3913
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+ + ++ +E D + + + + P + K L++ I+L
Sbjct: 3914 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 3969
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
G P+ V WY++GK+L A A +N+ YK N+
Sbjct: 3970 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4028
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G +S + ++ P IT + +K + E +V P V WYKNG +++ +
Sbjct: 4029 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4085
Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
+ I K T + IK R + Y I NTAG SS ++T+K
Sbjct: 4086 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4133
Score = 202 bits (494), Expect = 2e-51
Identities = 265/1127 (23%), Positives = 450/1127 (39%), Gaps = 106/1127 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G +L+ P+ +I W G+EI P + + D L I +
Sbjct: 3862 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 3917
Query: 705 EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
Y VV + +G A L +K KEP ++I+ L+ +V G + L + G+P+
Sbjct: 3918 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 3976
Query: 764 PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
T+ W KN K + K + + D + + V+D G Y ++ N G A +S
Sbjct: 3977 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4035
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876
ITVE P +P + Q IT E V N P I WY+N + I P S
Sbjct: 4036 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4086
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
I + +LVI N + D+ YK V N+AG++ A++T+ K K + K
Sbjct: 4087 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4144
Query: 937 SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991
E + +G ++ E + +W + IS + I + +
Sbjct: 4145 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4204
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D G V ++ K + PE +R L++ E+ E D + +VE+++ V
Sbjct: 4205 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4264
Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105
W ++ + IKP + + +K G + +L I + D +Y +L + + C + + +
Sbjct: 4265 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4323
Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159
P +I+ L++ V + ++++ +++W+K+G E++ + +
Sbjct: 4324 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 4383
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214
+ L I D G Y +GN K +++ V+ + F+ +T+
Sbjct: 4384 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 4443
Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267
LT++ I E +V W K V++ ++ T+ ++ TL IR + D +Y
Sbjct: 4444 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYR 4503
Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ +T+ KV V E PK V + G V + P+P +
Sbjct: 4504 VTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ 4563
Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
W +N IK + T + + LTI+ V D G K +N G D +
Sbjct: 4564 WFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 4622
Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437
G + L WD G+ I V+ EW K I T
Sbjct: 4623 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 4682
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480
T I+N + + R + E DI +ET Y+V ++E K +
Sbjct: 4683 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 4741
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535
+P + PL++ T + I L+C +P+ V WY+DG L+ T YE
Sbjct: 4742 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 4801
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587
Y+C+A N HG + TSC V ++ ++ V E K V G
Sbjct: 4802 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 4861
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646
D + + + G P PE+ WY+NG L N I T+ + + + + E S Y E
Sbjct: 4862 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 4921
Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685
A N T T+ V++ L +KP EG P + E+S SV++
Sbjct: 4922 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 4968
Score = 177 bits (430), Expect = 9e-44
Identities = 287/1251 (22%), Positives = 485/1251 (38%), Gaps = 155/1251 (12%)
Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
V+ L P G + + P+ +I W++ I PS Q D DN LVI +
Sbjct: 3854 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 3912
Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
+DA + V + G + D +TV L
Sbjct: 3913 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 3946
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691
P K + Q V GS I LE P+ + W G+E+ ++ I+ D + Y
Sbjct: 3947 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4005
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750
VL+I + G Y V N G A+ + + EP ++PLK + +GE
Sbjct: 4006 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4058
Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ S + PR + W KN KP + DT ++K D Y +
Sbjct: 4059 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4117
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866
EN+ G AE+SA +TV++ + I + E V KG K+V V P + W
Sbjct: 4118 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4172
Query: 867 YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
R+ +IS + I + D L+I + D + D+G+Y N +GK+ A+ +D
Sbjct: 4173 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4230
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984
EK V+ L+ + E EG + + + S V KWY N +EI H E + G
Sbjct: 4231 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4289
Query: 985 XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
D G V+ D ++S L VVK + + + L+D +V+E L+V
Sbjct: 4290 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4349
Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095
++ + W ++G+ +KP + + FE++ + L I ++ D G Y +L D+
Sbjct: 4350 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 4409
Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143
+VV + ++ L++ +V +G+ T + + G+ V W KDG
Sbjct: 4410 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 4468
Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193
+Q + I ++ +DG L+I D G+Y N S C +T E+
Sbjct: 4469 VVLQKDDRITMRVALDGTAT-LRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQ 4527
Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244
PS F + L +P + + + V +P TL W+ I+ ++ TL
Sbjct: 4528 PSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ--WFLNGIPIKFDDRITLDDMADG 4585
Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
I DV++ KC E+ E C + + +PP+ +
Sbjct: 4586 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 4645
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354
RI G + + A P EW + K I+ HT + ++D + + I E +D
Sbjct: 4646 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 4704
Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
G+Y N G A+ + V IL+ + + + D+ N G
Sbjct: 4705 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 4761
Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458
+ V+ + W + ++TSIQ L N S +R A N
Sbjct: 4762 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 4821
Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
+ S + +E K + P K L ++ + + L C G P P++ WY
Sbjct: 4822 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 4881
Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
R+G+ L+ T + Y+C A N HG+ +T +Q
Sbjct: 4882 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 4941
Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+KP ++ +S+ + + + E VT G+P P V W K+G L
Sbjct: 4942 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 4997
Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
D + + + V +RIK Y A+N G+++ + +++ D
Sbjct: 4998 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5048
Score = 176 bits (429), Expect = 1e-43
Identities = 260/1229 (21%), Positives = 496/1229 (40%), Gaps = 133/1229 (10%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VAT 567
AP+F + L+ + ++ E +V G P + WF+ + + +M + + V T
Sbjct: 2548 APVFEQGLKKTSVKEKEEIKMEVKVGG-SAPDVEWFKDDKPVSEDGNHEMKKNPETGVFT 2606
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
LV+++ DAG +T A N AG T E EA ++
Sbjct: 2607 LVVKQAATTDAGKYTAKASNPAG----TAESSAEAEVTQS-------------------- 2642
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
LE PTF ++ V L + +P+P + WL G+ + D + +A
Sbjct: 2643 -LE--KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEG 2699
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
Y +K ++ G Y A N GEA + PP+ +E L + V+
Sbjct: 2700 SGSYSITIKDARLE--DSGKYACRATNPAGEAKTEANFAV-VKNLVPPEFVEKLSPLEVK 2756
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGV 802
+ ES LS +VVG P P++ W K++ P+ + ++ + S+TI ++ D G+
Sbjct: 2757 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQ-GDVGI 2815
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y+ +A N G A T+A + ++ PP F + + + V+E+ T+ L V PVP
Sbjct: 2816 YSCRARNEAGEALTTANFGIIR----DSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVP 2871
Query: 863 SITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
++ W+++++ I+ S ++ + L I E D G Y C A+N AG++ A
Sbjct: 2872 NVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGE-DVGVYTCKATNEAGEAKTTAN 2930
Query: 921 VTI--DVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ + ++E FV+ L K YE E+GK +++ + KW+ + I+ +D++ +I
Sbjct: 2931 MAVQEEIEAPLFVQGL-KPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIA-IDNQHVI 2988
Query: 977 Q---EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
+ E D G C ++ V + IP++ + Q E +V
Sbjct: 2989 EKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAE----EV 3044
Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
L +E ET V E D +++ K NK H + + +N + G++ +
Sbjct: 3045 KPLFIEPLKETFAV--EGDTVVLECKVNK-----ESHPQIKFFKNDQPVEIGQHMQLEVL 3097
Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
E ++T+ E + + + VN KA +L +IQF+ ++
Sbjct: 3098 EDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADL--------------KIQFAAKVE 3143
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
+ + +L ++ G++ VG++ + T + F + L V
Sbjct: 3144 EHVTDESGQL-------EEIGQFET-VGDTASSKTDT-GRGAPEF-VELLRSCTVTEKQQ 3193
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL 1271
A L ++ E + W K+ +E + + D TL T+ D EY C
Sbjct: 3194 AILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAE 3253
Query: 1272 DAKSTTKLKVEVV---EFPPKI----VDYEREYR---IKRGSDVTLLVDYQAFPQPNDEW 1321
+ + + ++ E PKI D+ + + + G L P+P+ +W
Sbjct: 3254 NEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKW 3313
Query: 1322 IVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADVEMNVTIL 1378
N + +K K ++D + LT+ + D Y+ N G +DV + V
Sbjct: 3314 YKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEP 3373
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQ 1437
+ +P + I E + +G + + + + + + ++ TQ
Sbjct: 3374 AQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQ 3433
Query: 1438 TS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTE 1494
I++ KT+ +R N+ ++++ + T + S T ++K L ++
Sbjct: 3434 RLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKGLTDVNVT 3485
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYK 1549
I L+ G P+ V WY+ + + +++ T E+ Y+
Sbjct: 3486 QGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYR 3544
Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIEGIPPPEV 1604
+ D VE+S V + K IS K Q G ++ IEG P +V
Sbjct: 3545 VVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEG-KPKDV 3602
Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYKNG+++++ K ++ + + I + + +Y++ A+N AG + + V
Sbjct: 3603 KWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSA 3660
Query: 1665 KPSKPEG--PVIMREISRESVTIEWKPPL 1691
KP G P +++ + ++ K P+
Sbjct: 3661 KPEIVSGLVPTTVKQGETATFNVKVKGPV 3689
Score = 171 bits (417), Expect = 4e-42
Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%)
Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563
MAP F+ K++ G + FEC V W + I+ ++ +
Sbjct: 2245 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2304
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
LV+ V PEDAG +TC+ +N AG + L V L +
Sbjct: 2305 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2353
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
P F + + ++LEC+++ P+P ++WL + I + S+
Sbjct: 2354 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 2400
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
+ES + + IT+ + +G YT +A N EG + L T + E P + L++
Sbjct: 2401 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 2455
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792
+ GE ++LS V G+P+P + + ++ K + TK +TH ++
Sbjct: 2456 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 2514
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+D Y A NS G A +++ IT + E P+F ++ +VKEK IK+
Sbjct: 2515 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 2568
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911
+V P + W+++++ +S + E + ++ + D+G Y ASN
Sbjct: 2569 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 2627
Query: 912 AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
AG +SS A VT +EK TFV+ L + E T+ + + S +W + + +
Sbjct: 2628 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 2687
Query: 969 GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020
I ++ D G C + + + VVK + PEF+
Sbjct: 2688 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 2747
Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077
KL EVKEK+ L V+ + + V W +D I N + +K+ + L I
Sbjct: 2748 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 2806
Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131
+ D G YSC R+E+ TA ++ +PPE +L+ +V + + T ++++T
Sbjct: 2807 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 2864
Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182
G + V WFKD I N HI +G L I +D G Y+C E G
Sbjct: 2865 VIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 2924
Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237
+K TA + V+E + F L + V A L V + + +V W+K I+
Sbjct: 2925 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 2983
Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286
+ + TL+I+ D +YTC + K T +LK+ F
Sbjct: 2984 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3043
Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344
P ++ +E G V L P ++ N + ++ +H + + + +
Sbjct: 3044 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3103
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
LTI+ + D G Y+ N G A+ ++ I
Sbjct: 3104 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3136
Score = 171 bits (415), Expect = 6e-42
Identities = 215/924 (23%), Positives = 354/924 (38%), Gaps = 76/924 (8%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G T++ + G P P ++W+ ++ SQ+ ++ + + T+ I+++ + +G
Sbjct: 2031 EGDTLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKI-HSEKGTYTVTIKDITCDYSGQVV 2089
Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
C A N G A+S L+V G ++ + T KP
Sbjct: 2090 CEAINEYGKATSEATLLV----LPRGEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSL 2145
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDM-HMYCSVLKIT 698
+ +I L L I D PD ++ I E+D + C+ IT
Sbjct: 2146 TWYINNKEI-LNSDLYTIVTDDKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMIT 2204
Query: 699 NVK-KFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
F E A G + SL + P+ I +K ++G S
Sbjct: 2205 YTSDMFSESESEAQAEEFVGDDLTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSA 2264
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALP-------TKSDGDTHSITILKPKKVKDEGVYTL 805
+ V W K+ K ++ + T +G +L +D G YT
Sbjct: 2265 VFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTC 2324
Query: 806 KAENSEGIAETSAVITVEEPTEENAE--PPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
EN+ G A +TV E E+ +E P FI Q+ T K + L +V P P
Sbjct: 2325 IVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPK 2384
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEID-SGDYKCVASNSAGKSSHGARVT 922
++W +N+ I+ ++ +G +E V T SE+ G Y C+A N+ G S A +T
Sbjct: 2385 VSWLHDNKTITQESITVESVEG--VERV-TITSSELSHQGKYTCIAENTEGTSKTEAFLT 2441
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQT-----------SHTVSTKWYHNKKEISGMD 971
+ E F K LQ E G+ ++L C S + +TK K S
Sbjct: 2442 VQGEAPVFTKELQNK-ELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRI 2499
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETST-MLVVKETIPEFIRKLQDFE 1027
E Q D+ K I + TST + K P F + L+
Sbjct: 2500 AIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKTS 2559
Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH--IRKLYIRNTSVHDEG 1085
VKEK+ +EV++ DV W +D + + N ++ +K + L ++ + D G
Sbjct: 2560 VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGN-HEMKKNPETGVFTLVVKQAATTDAG 2618
Query: 1086 EYSCI------LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG--DALV 1137
+Y+ + S AEVT P + L +V AT + + KG D V
Sbjct: 2619 KYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTV-KGVPDPSV 2677
Query: 1138 RWFKDGSEIQF-SNHIQLTIDGK-KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195
W KDG +Q S+H+ ++G + I D L+D+G+Y+C N A T +
Sbjct: 2678 EWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEA-KTEANFA 2736
Query: 1196 INFTLRLPEFI--LVPANT----DAYLTVE-IPDETLDVTWYKKKS--VIEDTEKFTLIS 1246
+ L PEF+ L P L+V+ + V W+K + I++ +
Sbjct: 2737 VVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQT 2796
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
V +L I + D Y+C +A +T + PP+ R ++
Sbjct: 2797 AVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQ 2856
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKL 1360
+ L V P PN EW + K I + D S +LTIK+ D G+Y
Sbjct: 2857 ETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTC 2916
Query: 1361 RLENNCGHADVEMNVTILDKPSPP 1384
+ N G A N+ + ++ P
Sbjct: 2917 KATNEAGEAKTTANMAVQEEIEAP 2940
Score = 169 bits (412), Expect = 1e-41
Identities = 255/1135 (22%), Positives = 433/1135 (38%), Gaps = 126/1135 (11%)
Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
TF K K Q + EG + P + W G+EI P+ + ++D Y V
Sbjct: 4044 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4101
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
+K N + TY +V N GEA L +K + ++++ L+ +V +G ++
Sbjct: 4102 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4159
Query: 755 SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P + W ++ + A + K D T+ + I+ +KD G YT++ N
Sbjct: 4160 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4217
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
G A++ A V+E E + + I + E V+ PV + WY+N+
Sbjct: 4218 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4269
Query: 871 EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
+ I P+ + G + EL I + D DYK V SN+AG A +T+ V
Sbjct: 4270 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4328
Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984
+ K + EE + V L+ + KWY N +E+ G E + G
Sbjct: 4329 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 4388
Query: 985 XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033
D G + ++ K + S +V K + P F+ L+D EV+E D+
Sbjct: 4389 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 4447
Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
L+ I E +V+WE+DG +++ L IR+ D G+Y +
Sbjct: 4448 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAK 4507
Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142
+E+ +A +VTV E P+ + L+ G+K F +++ ++WF +
Sbjct: 4508 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLN 4567
Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193
G I+F + I L DG L I D +D G C N T E +
Sbjct: 4568 GIPIKFDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 4626
Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244
LR P VP D + V P + T +V W+K IE T +
Sbjct: 4627 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 4685
Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290
+ V I I E D Y CV ++ A++ +VE++E + PKI
Sbjct: 4686 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 4745
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349
+ + G + L A P+ + W + ++ T + +A+L I
Sbjct: 4746 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 4805
Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
D G Y+ N G + +V + K + + W + G+
Sbjct: 4806 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 4862
Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455
S + V +W ++N +T +TS +L N S +R A
Sbjct: 4863 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 4922
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509
N + T + +T+ KP L +++ I+L C G+P
Sbjct: 4923 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 4982
Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561
P V W +DG L + ++ + N Y+C+A N++G T
Sbjct: 4983 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5042
Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
S VV Q P T+ D++ G + ++ P PE++WYK+G
Sbjct: 5043 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5100
Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I+ + + + + I Y + A+N +GT+ + T V P
Sbjct: 5101 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5155
Score = 156 bits (379), Expect = 1e-37
Identities = 258/1109 (23%), Positives = 438/1109 (39%), Gaps = 156/1109 (14%)
Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
F++ L+ + +G +F + PR + W++ IKP+ F + D LVI+
Sbjct: 4045 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4103
Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
+DA T+ V +N AG A S+ +L V+ I++G
Sbjct: 4104 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4145
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+ + Q V +G+ ++ E ++ PE D+ WL I N ++ + D Y
Sbjct: 4146 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4195
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
++ ++K G YTV +N G+A K E P+++ L+++ + +G+
Sbjct: 4196 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4249
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
+ +V P + W KN++ +K L K G + ++ D Y +
Sbjct: 4250 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4308
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N+ G ++SA +TV +P ++ +++ V+E ++L +V P I WY+
Sbjct: 4309 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 4362
Query: 869 NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926
N + + P ++ E+ E +T S+ D G Y+ V N G+ G+ V +
Sbjct: 4363 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 4422
Query: 927 K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975
K F+ L K E EEG + L+C + + W + + D +
Sbjct: 4423 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 4481
Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026
+G D+G + K++ S K T+ P+F+ L+
Sbjct: 4482 ALDG-TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 4540
Query: 1027 EVKEKDVAILEVEINSETADVV-WERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
D V++ + W +G IK + D G+ L IR+ D
Sbjct: 4541 AALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYC-LTIRDVREEDF 4599
Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128
G CI ++E+ T E TV E PP L ++++ G+ E
Sbjct: 4600 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 4658
Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
+ A V WFKDG +I+ + H ++ T+DG ++KI + D G Y C E+G
Sbjct: 4659 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 4717
Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
++ A VE P IN L E V L+ ++ V
Sbjct: 4718 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 4774
Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
WYK + D+ + TL I TE+D Y CV +A T V V+
Sbjct: 4775 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 4834
Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334
P + V E E RG TL P P +W N ++++ T
Sbjct: 4835 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 4894
Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386
+ S D S SLT+ + +D GIY+ EN G A V+M + +KP GK
Sbjct: 4895 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 4953
Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437
P ILE+ S+ N+ E + TG N ++ + I+ + EW + + Q
Sbjct: 4954 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5013
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490
I+N + +R A NE + S TT+ + + + T Q P + +
Sbjct: 5014 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5069
Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+ T + ++L C P P++ WY+DG
Sbjct: 5070 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5098
Score = 149 bits (361), Expect = 2e-35
Identities = 173/749 (23%), Positives = 292/749 (38%), Gaps = 93/749 (12%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S E + F+ L+ +G + +C + G P P++ W + +++ M
Sbjct: 4424 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 4483
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
D ATL IR D G + AKN AG A+S ++ V ++ G + +
Sbjct: 4484 DGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTV----TEQGEQPS---------- 4529
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
P F K G ++ +P+P + W G I D+ I++
Sbjct: 4530 ----------KPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITL 4579
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734
+D + YC L I +V++ GT +A N G + G + P
Sbjct: 4580 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 4636
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
P+ PL + G+ + + V NP + W K+ K ++ T+ +K
Sbjct: 4637 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 4696
Query: 794 --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846
P + D GVY A N G AET A VE E EE P ++ TV
Sbjct: 4697 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 4756
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
I+L +V P S+ WY++ + + ++ + + N +E D G Y+C
Sbjct: 4757 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 4816
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956
VA+N+ G + V + V K K ++ + T + G + L+C +
Sbjct: 4817 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 4876
Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007
KWY N + + R +I+ D G+ +C K Q T+
Sbjct: 4877 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 4935
Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055
+ + +T P+FI +L D V +V LE ++ V W +DG +
Sbjct: 4936 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 4995
Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101
I+ + ++ E + +L I+N +VHDEG Y C+ +E+ +A V
Sbjct: 4996 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5055
Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158
PP ++ + + +G E ++ + W+KDG+ + S+ IQ+++ DG
Sbjct: 5056 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5115
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
L I C DD G Y N TA
Sbjct: 5116 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5143
Score = 147 bits (355), Expect = 1e-34
Identities = 229/1083 (21%), Positives = 415/1083 (38%), Gaps = 90/1083 (8%)
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P PDI W ++ DE + + D + I V+ G YT +A N
Sbjct: 570 KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626
Query: 716 EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
G+AS ++ EKE PP + L+ ++G+ + +V G P P + W +++
Sbjct: 627 YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686
Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
P++ + DG T + I + + D GVYT+K +N G E+ A + V+ ++N
Sbjct: 687 PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
P F + + E ++ + +T +P P I W+ N + +S SE + + L
Sbjct: 746 VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948
I +V D G C SN G +S R+ + V TF K L+ +E TV+
Sbjct: 806 TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863
Query: 949 ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
E S T K+ +G + EI+ +G G I +++
Sbjct: 864 EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923
Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
E+ L V++ + P F++ ++D VK + A+ E + + +V W +G
Sbjct: 924 HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104
+ E H KL I S G C + R E+ V + +
Sbjct: 984 HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+
Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101
Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLT 1217
I + ++DAGE NS + A LTV++ F LR P + V ++A +
Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLR-PVSLTVEKGSEAVFS 1160
Query: 1218 VE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT-----LIIRKCTEDDQCEYTCV 1269
IP T + W + D ++ ++ + L I T + + +
Sbjct: 1161 AHAFGIPLPTYE--WSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTI 1218
Query: 1270 LLDAKST-----TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WI 1322
+ A++T T ++ + P R+ +++ + T L ++ + E W
Sbjct: 1219 SVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQT-VNKTDLAHFEVVVEHATECKWF 1277
Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
++ K I + S D + +G + N G + + + +L+ P
Sbjct: 1278 LDGKEITTAQGVTVSKDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPK 1337
Query: 1383 PPGKPNILE--IDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQT 1438
KP + D + + + +Y + + D +++KN + ++
Sbjct: 1338 ETKKPEFTDKLRDMEVTKGDTVQMDVIALHSPLYKWYQNGNLLEDGKNGVTIKN-EENKS 1396
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
S+ S + A NEV S++S ++ +P V K++T + E
Sbjct: 1397 SLIIPNAQDSGKITVEASNEVGSSESSA-----QLTVNPPSTTPIVVDGPKSVTIKETET 1451
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFN 1554
E G P P V W + K ++ ++ E+ K A N
Sbjct: 1452 AEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQN 1511
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE-----WLVTAVIEG-IPPPEVIWYK 1608
G + S ++ +P + + KV DE W ++G P EV W
Sbjct: 1512 SAG--QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRW--NLELDGPSPGTEVSWLL 1567
Query: 1609 NGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
NG L ++D + + T + I E K S T +A N AG + V
Sbjct: 1568 NGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNK 1627
Query: 1668 KPE 1670
KPE
Sbjct: 1628 KPE 1630
Score = 143 bits (347), Expect = 1e-33
Identities = 214/1008 (21%), Positives = 387/1008 (38%), Gaps = 76/1008 (7%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
Q S + +V G P P ITW K++ + + SD D + P +V D G YT
Sbjct: 561 QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N G A TSA V + E+ A PP F+ + ++ KE I V P P +
Sbjct: 621 CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
W +++ + PS +DG+ +L I + + D+G Y N G A + +
Sbjct: 680 VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738
Query: 924 -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
D +K Q + E +EG+ V + + + + W+ N K +S + + I
Sbjct: 739 ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798
Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031
E G++ C ++ S + V P F + L+D V+EK
Sbjct: 799 EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858
Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088
+ EV+++ + + G+ +K + + ++ I NTS+ HD GE
Sbjct: 859 STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917
Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137
++E TAE +TV + P + +++Q V G A FE + + V
Sbjct: 918 AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977
Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
WF +G ++ Q S +++ KL I AG C VG + A L V
Sbjct: 978 TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035
Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
P + P+F+ + + D + E+ E VTWY K ++ +++ +
Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301
+ I+ +D E V +++ + KL V+ F P+ +++
Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKK----CKHTKPSIDSKSASLTIKKVENTDAGI 1357
GS+ P P EW VN + ++ + T+ AS+ + +
Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEV 1213
Query: 1358 YKLRL----ENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNSTI 1412
L + EN G + +TI K P P L++ + + ++T
Sbjct: 1214 NHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATE 1273
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
+ ++ +EI T + ++V Q + + + +V + + + ET K
Sbjct: 1274 CKWFLDGKEITTAQGVTVSK--DDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELK 1331
Query: 1473 VIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY 1529
V++ K + P L+++ + +++ I + P WY++G L+ K T
Sbjct: 1332 VLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLEDGKNGVTI 1389
Query: 1530 ENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHK 1585
+N + A N+ G E+S + + P++ + + K
Sbjct: 1390 KNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKET 1449
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
E+ T I G P P V W N +E + E ++I K + +
Sbjct: 1450 ETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKV 1507
Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692
A N+AG S + LKV P+ + +++ E + W LD
Sbjct: 1508 TAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 1555
Score = 143 bits (346), Expect = 1e-33
Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+ + AP L K G ++ C+V+ PR + W++ ++ + Y++D
Sbjct: 4737 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 4796
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
ATL I + ED G + CVA NA G +++ + V+ P + E
Sbjct: 4797 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 4843
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
G P F+K + D G L+C + P P+I W G+ +
Sbjct: 4844 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 4894
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733
IE+ CS L + EG Y A N G+A +L K K E +
Sbjct: 4895 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 4953
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
PP+ I L M V G + L +V G P P++ W K+ P+ ++
Sbjct: 4954 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5013
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845
+ +K V DEG Y A N G A T + + +++ ++PP F + ++
Sbjct: 5014 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5073
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
E +KL +V +P+P + WY++ I++PS+ I + + + ++ D G Y+
Sbjct: 5074 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5133
Query: 906 CVASNSAGKSSHGARVTI 923
+A+N +G + T+
Sbjct: 5134 VIATNPSGTAQDKGTATV 5151
Score = 139 bits (337), Expect = 2e-32
Identities = 180/762 (23%), Positives = 288/762 (37%), Gaps = 105/762 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F L + P G + EC V+ P ++ WF+ I+ + ++ D +
Sbjct: 4637 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 4696
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I D G + CVA N G A T+ + + +H E +
Sbjct: 4697 IIPFEESDIGVYMCVAVNELGQAE--TQATYQVEILEHVEE------------EKRREYA 4742
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
I P K V+ G I L C++ AIP + W G + D S+ E D
Sbjct: 4743 PKINPPLEDKT----VNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG- 4797
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQVIEPLKS 743
+ L I + + G Y VA N G + + +K E E P + L
Sbjct: 4798 --TATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVD 4855
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKALPTKSDGDTHSITILKPKKVK 798
+ +G+S L V G+P P I W +N N P + T DG S+T+ +
Sbjct: 4856 LWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC-SLTV-NESTMS 4913
Query: 799 DEGVYTLKAENSEGIAETSAVITV-------EEPTEENAEPPLFINRFQEITVKEKGTIK 851
DEG+Y +AEN+ G A+T A V E+P + +PP FI +++V I
Sbjct: 4914 DEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVID 4973
Query: 852 LVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVAS 909
L +VT P PS+ W ++ +I S N + + +L I N D G Y+CVA+
Sbjct: 4974 LECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVH-DEGTYRCVAT 5032
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQT--SHTVST 958
N G ++ + V +D + V + T EG+ + LEC+ S
Sbjct: 5033 NENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEM 5092
Query: 959 KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVV 1012
WY + ++ D +I + D G+ + I + Q+ T V
Sbjct: 5093 VWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVK 5152
Query: 1013 K------------------ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
K P+ + L++ + EK L + + + + W +DG
Sbjct: 5153 KLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDG 5212
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVTVVELPP 1107
E + P E + +L + + + D G Y C+ + SC V + P
Sbjct: 5213 ERVFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKP 5272
Query: 1108 EII-------------TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152
I T L ++ G+ TFE L G+ ++W KDG E+ I
Sbjct: 5273 RDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFEC-LPFGNPFPSIKWLKDGLELFSDEKI 5331
Query: 1153 QL--TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
++ DG Q+L + D G + C N TA E
Sbjct: 5332 KMEAAADG-TQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 5372
Score = 135 bits (327), Expect = 3e-31
Identities = 178/787 (22%), Positives = 309/787 (39%), Gaps = 50/787 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ K + V +G + ++ ++A+ P W G ++ D V I+++ + S
Sbjct: 1342 PEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGN-LLEDGKNGVTIKNEENK--S 1396
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I N + G TV A N G + L + P V++ KS+ +++ E+
Sbjct: 1397 SLIIPNAQ--DSGKITVEASNEVGSSESSAQLTVNP-PSTTPIVVDGPKSVTIKETETAE 1453
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK--AENSE 811
A + G P PT+ W N K V+ T + T + LK K E T+K A+NS
Sbjct: 1454 FKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSA 1513
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITWYRNN 870
G A + V E N + P F ++ + E ++ + +P ++W N
Sbjct: 1514 GQDSKQADLKV----EPNVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNG 1569
Query: 871 EIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID--VEK 927
+ ++ S+T+ G+ + I E+ SG A N+AG+ A+VT++ +K
Sbjct: 1570 QPLTKSDTVQVVDHGDGTYHVTIAEAKPEM-SGTLTAKAKNAAGECETSAKVTVNGGNKK 1628
Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREI--IQEGRXXXX 984
FV+ Q T E T + + WY N K++ + ++ + E
Sbjct: 1629 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 1688
Query: 985 XXXXXXXXDVGVIKCIV-----KDQETSTMLVVKET-IPEFIRKLQDFEVKE-KDVAILE 1037
G I+ K Q T+ + V K+T +P+F + D +VKE +DV
Sbjct: 1689 RIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKFTA 1748
Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL------ 1091
V W +GE + N +K G + I + GE SC
Sbjct: 1749 NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGE-HTIEISAVTPEQAGELSCEATNPVGS 1807
Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE--IELTKGDALVRWFKDGSEIQFS 1149
+ V V P L+++ + +G + + + K + W KDG EI
Sbjct: 1808 KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSD 1867
Query: 1150 NHIQLT-IDGKKQKLKIYDCDLDDAGEYS----CEVGNSKCTAILTVEE--PSIN--FTL 1200
H ++ + KL I L+D G + E G ++C+A L V + P F
Sbjct: 1868 GHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQS 1927
Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
+ L +T + D T V WY ++ TE + + T+ I T
Sbjct: 1928 DIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTA 1987
Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQP 1317
D + CV + + + P V++E + + G + L P+P
Sbjct: 1988 DMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEP 2047
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W VN K +++ ++ K + + ++TIK + +G N G A E + +
Sbjct: 2048 VVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLV 2107
Query: 1378 LDKPSPP 1384
L + PP
Sbjct: 2108 LPRGEPP 2114
Score = 134 bits (323), Expect = 9e-31
Identities = 227/1107 (20%), Positives = 414/1107 (37%), Gaps = 74/1107 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYC 692
P F +P + V++GS+ + IP P W G ++ E V +
Sbjct: 1140 PEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGA 1199
Query: 693 SVLKITNVKKFQEG---TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
S+L I + E T +VVA N G L I+ + P++ LK V +
Sbjct: 1200 SILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKT 1259
Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ + +VV W + K + T S D + G ++ A
Sbjct: 1260 D--LAHFEVVVEHATECKWFLDGKEITTAQGVTVSKDDQFEFRCSIDTTMFGSGTVSVVA 1317
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N+ G ET + V E +E +P F ++ +++ V + T+++ +P+ WY
Sbjct: 1318 SNAAGSVETKTELKVLETPKETKKPE-FTDKLRDMEVTKGDTVQMDVIALHSPL--YKWY 1374
Query: 868 RNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+N ++ + +T + L+I N DSG ASN G S A++T++
Sbjct: 1375 QNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DSGKITVEASNEVGSSESSAQLTVNPP 1431
Query: 927 KVT-FVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXX 983
T V KS +E +T + S + KW N+K + I+
Sbjct: 1432 STTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYT 1491
Query: 984 XXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKETI--PEFIRKLQDFEVKEKDVAILE 1037
G +K ++ Q++ L V+ + P+F +L D E +
Sbjct: 1492 LKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWN 1551
Query: 1038 VEIN--SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
+E++ S +V W +G+ + + + I G + ++ +
Sbjct: 1552 LELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNAA 1611
Query: 1096 --C--TAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQF 1148
C +A+VTV PE + QN + F +T K V W+ + ++
Sbjct: 1612 GECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQ 1671
Query: 1149 SNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTL 1200
S +++ + K ++I ++ G E G + TA L V++ + FT
Sbjct: 1672 SEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTT 1731
Query: 1201 RLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
+ + V D T + V W + T+ + T+ I T
Sbjct: 1732 NMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVT 1790
Query: 1260 EDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF- 1314
+ CE T + K +L V+ V P + I G ++TL+
Sbjct: 1791 PEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKNLEDRLITEG-ELTLMDAKLNIV 1849
Query: 1315 -PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
P+P W+ + I H K + S L+I + + D G ++ E+ G A+
Sbjct: 1850 KPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECS 1909
Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPEN-----TGNST-IIYYVVEYQEIDTTE 1426
++ ++ K P KP + D + IN+ + TG+ T + + + Q + TE
Sbjct: 1910 ASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATE 1967
Query: 1427 WISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
+ N T I + + + + + A N+ + S T KV+ ++ E
Sbjct: 1968 DTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA--GEVS-TEGPLKVVAPIPVE---FE 2021
Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545
L + T + ++L + G P+P V+WY +GKKL+ ++ +
Sbjct: 2022 TSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDIT 2081
Query: 1546 XXYK----CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIP 1600
Y C A N++G+ + + + + E + + + G + + V G P
Sbjct: 2082 CDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTGTKVVHKVVFTGDP 2141
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS-HSSKYTIEASNTAGTSSVEVT 1659
P + WY N ++ N Y I T +KTS + I H + +A N AG S
Sbjct: 2142 KPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTAN 2201
Query: 1660 LKVY--DKPSKPEGPVIMREISRESVT 1684
+ Y D S+ E E + +T
Sbjct: 2202 MITYTSDMFSESESEAQAEEFVGDDLT 2228
Score = 133 bits (321), Expect = 2e-30
Identities = 185/819 (22%), Positives = 326/819 (39%), Gaps = 81/819 (9%)
Query: 936 KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989
K + ++G + + EC T V KW + KEI + + EG
Sbjct: 2254 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2313
Query: 990 XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036
D G CIV KD +T+ V++ + PEFI LQD K + +L
Sbjct: 2314 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 2373
Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
E ++ E V W D + I + E + ++ I ++ + +G+Y+CI +
Sbjct: 2374 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 2431
Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143
T++ +TV P LQN++++ G K + KG + K
Sbjct: 2432 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 2490
Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195
++I S+ I + D ++ I +D Y NS TA T VE P
Sbjct: 2491 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 2550
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253
L+ V + + V++ DV W+K K V ED + + TL
Sbjct: 2551 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 2607
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309
++++ D +YT + T + + EV + P V +K TL V
Sbjct: 2608 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 2667
Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P+ EW+ + + ++ H ++ S S S+TIK D+G Y R N G
Sbjct: 2668 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 2727
Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
A E N ++ PP K + LE+ + T + VE+ + DT
Sbjct: 2728 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 2782
Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
I ++ + QT++ +L N + + Y+ + + + TT + +I+++
Sbjct: 2783 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 2840
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534
P + L+ + E ++L G P P V W++D K + AK
Sbjct: 2841 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT 2900
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593
Y C A N+ GE +T+ + +Q++ + + +K + + G +
Sbjct: 2901 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 2960
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651
+EG P PEV W+K+G + D ++ I K + + + IK+ + KYT +A+N A
Sbjct: 2961 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3020
Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686
G LK+ ++K + E + E +E+ +E
Sbjct: 3021 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3059
Score = 130 bits (313), Expect = 1e-29
Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K +++ P F + L G + +C V G P P+I W+R +++ +
Sbjct: 4837 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 4896
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
D +L + E D G + C A+NA G A + V+ L
Sbjct: 4897 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 4942
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ EG PP F + V G+ I LEC++ +P P + W G ++ D
Sbjct: 4943 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5000
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732
+ E+ +Y L+I N EGTY VA N G A+ +++ G
Sbjct: 5001 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5058
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789
+PP+ + + +G+ + L +V +P P + W K+ A+ T SD S+
Sbjct: 5059 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5114
Query: 790 ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832
T+L P V D+G+Y + A N G A+ TV++ P + A +
Sbjct: 5115 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5174
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890
P + + I + EK + +L + + +P P+I W+++ E + P + ++ DG EL
Sbjct: 5175 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5233
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
V+ + + D+G Y+CVA N+ G + V +
Sbjct: 5234 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5265
Score = 127 bits (306), Expect = 1e-28
Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+ + AP +E L P+ + + C+ G P+P I WF+ + P Q+ D
Sbjct: 5170 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5229
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
V LV+ +DAG + CVA+N G S+ T V D
Sbjct: 5230 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5275
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
+ I EG P F+ + G + EC P P I WL G E+ DE I +
Sbjct: 5276 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5335
Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731
+D L +++V EG + VA N G AS L I+ GE
Sbjct: 5336 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 5392
Query: 732 KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782
E P++ L +M + +G V + G P PT+ W K+ + + K +
Sbjct: 5393 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 5452
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834
+ H + I+ DEG Y+L+A N G A+T + + P +A+ PP
Sbjct: 5453 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 5511
Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893
F+ + + V V +P P + W+ N + I P I Q+ G + L+I
Sbjct: 5512 FVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 5571
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ E D+G+Y A NS G +S A + + V + +K
Sbjct: 5572 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 5609
Score = 121 bits (292), Expect = 5e-27
Identities = 224/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
+P+ L D YT E I++ + E P V L P+G
Sbjct: 4199 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4251
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
F+ +V P Q+ W++ IKP+ + L I +D + V NA
Sbjct: 4252 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4310
Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
AG S+ L V P I++G+ ++P+
Sbjct: 4311 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4343
Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
+ L+ ++ IP+ I W G+E+ PD + E L I + KK G Y
Sbjct: 4344 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 4400
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764
VV N +GE V+ +K+ + P + PLK V +G+ + L + G P P
Sbjct: 4401 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 4460
Query: 765 TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
+ W K+ ++ + DG T ++ I KK D G Y + A+N G A +
Sbjct: 4461 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSAKK-SDIGQYRVTAKNEAGSATSDCK 4518
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+TV E E+ ++P F+ + + +V P P++ W+ N I + I
Sbjct: 4519 VTVTEQGEQPSKPK-FVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRI 4577
Query: 880 T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928
T + N L I +V E D G KC+A N G + H D+
Sbjct: 4578 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 4636
Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985
G + +EC + T +W+ + K+I H EI
Sbjct: 4637 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 4696
Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030
D+GV C+ ++ ET V +E P+ L+D V
Sbjct: 4697 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 4756
Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
L ++++ A VVW +DG ++ + +E+ G L I +++ D G Y
Sbjct: 4757 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 4815
Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
C+ + SC+ V V + P L + ++G+ T + +T GD
Sbjct: 4816 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 4874
Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
++W+++G ++ I+ + DG L + + + D G Y CE G +K A
Sbjct: 4875 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 4933
Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233
V E+P ++ + P+FIL ++ L I E V W K
Sbjct: 4934 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 4992
Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283
+ + +F ++ K L I+ T D+ Y CV + +TTK V +
Sbjct: 4993 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5052
Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
PP+ + R G + L A P P W + I+ + S+
Sbjct: 5053 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5112
Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
A+L I D GIY++ N G A + T+ P G
Sbjct: 5113 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5159
Score = 116 bits (278), Expect = 2e-25
Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
EKP +E P F+ +L G+ + EC+V G P P + W + + F+
Sbjct: 4945 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5003
Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ V L I+ D GT+ CVA N G S+TT+ V D G V
Sbjct: 5004 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5058
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
PP F+ K EG + LEC++ A P P++ W G + P
Sbjct: 5059 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5104
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
+ I +++ D + L I + +G Y V+A N G A +K +G +
Sbjct: 5105 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5161
Query: 733 -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778
+ P+++EPL+++ + + +S L + G+P+PTI W K+ + P L
Sbjct: 5162 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5221
Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829
D ++ +D G Y AEN+ G A TS + V +P +
Sbjct: 5222 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5281
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+ P F K ++ NP PSI W ++ + E I + +
Sbjct: 5282 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5341
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944
+I + + + G ++CVA+N G +S A + I+ ++ + L + + E EE K
Sbjct: 5342 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 5397
Score = 102 bits (244), Expect = 3e-21
Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%)
Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144
+ DES E+ P P+ IT++++ K KG+ A FE + TKG +W KDG
Sbjct: 2227 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2285
Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194
EI+ I++ T G + Q+L + + +DAG+Y+C V G C A LTV E
Sbjct: 2286 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2345
Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246
+ PEFI+ T + +E I + V+W + K++ +++ +
Sbjct: 2346 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 2405
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304
V++ T+ + + Q +YTC+ + + T+K + + V P + + G
Sbjct: 2406 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 2463
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356
+ L + PQP+ ++ S+ K + K T S I+ + + I ++ D
Sbjct: 2464 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 2523
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
YK N+ G A +T + +P + + + E + G++ + +
Sbjct: 2524 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 2582
Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
+ + + +K +T ++ T + ++ A A N +++S E +
Sbjct: 2583 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 2641
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527
++ PT + L + NE L+ GVP P V W +DG+ ++T AK
Sbjct: 2642 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 2697
Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586
Y C A N GE +T + + V E + + K
Sbjct: 2698 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 2757
Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644
+ ++ + G P P V W+K+ + D + I T + + I + ++ Y+
Sbjct: 2758 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 2817
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688
A N AG + + PE +R + RE T++ K
Sbjct: 2818 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 2862
Score = 90.6 bits (215), Expect = 1e-17
Identities = 86/357 (24%), Positives = 146/357 (40%), Gaps = 16/357 (4%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G PTF+K + + + EG L++ +L + P+P I WL G EI D + + E D
Sbjct: 1820 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 1879
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQ 748
+ S+L+ K +G T+ A + G A L + G P + + + +
Sbjct: 1880 LKLSILQ---TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTE 1936
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-- 806
G+++ + G+P P + W + V A + + + +K V + +K
Sbjct: 1937 GDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCV 1996
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G T + V P P F + T +E T+KL A + P P ++W
Sbjct: 1997 AYNKAGEVSTEGPLKVVAPI-----PVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSW 2051
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--D 924
Y N + + S+ I + + + I ++ + SG C A N GK++ A + +
Sbjct: 2052 YVNGKKLEESQNIKIHSEKGTYTVTIKDITCDY-SGQVVCEAINEYGKATSEATLLVLPR 2110
Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGR 980
E F++ L K V T S WY N KEI D I+ + +
Sbjct: 2111 GEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDK 2167
Score = 70.9 bits (166), Expect = 9e-12
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
+Y E + + + P+PDI W F+G +I S + L IT K
Sbjct: 5779 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 5838
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y A N G+A I++ + T P I+PL + + + + +V G P
Sbjct: 5839 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 5894
Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
P + W K +P+ + DG I+ +D G+Y+ A N G A TS
Sbjct: 5895 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 5954
Query: 820 ITVEEPTEEN 829
+TVE + N
Sbjct: 5955 VTVEAEGDYN 5964
Score = 64.9 bits (151), Expect = 6e-10
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
+++ I+K+ +++ + APIF +LR + FEC V P P++TW
Sbjct: 6864 ERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDF 6923
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
Q I++ S D D+NVA L++ P D G + C A N G S+ LI
Sbjct: 6924 QGKILE-SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI 6976
Score = 60.5 bits (140), Expect = 1e-08
Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531
K+++ ++P L++ TT+ +E + L C G P+PKV+W D K + T E+
Sbjct: 2347 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 2406
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589
Y CIA N G +T + +Q + PV T ++++ K +G++
Sbjct: 2407 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 2463
Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641
+++ ++G P P V +Y K K+ + I + + R I ++ +
Sbjct: 2464 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 2523
Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y A+N+ G TS+ ++T KV + P +G +E + +E K +E
Sbjct: 2524 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 2582
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
K E N+ K + + V T +++ + A NP G +E+
Sbjct: 2583 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 2633
Score = 57.6 bits (133), Expect = 9e-08
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565
S+ P F +KLRP + T+ + V G P P + WF+ I D+
Sbjct: 2839 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGH 2898
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608
TL I++ ED G +TC A N AG A +T + V EAPL G
Sbjct: 2899 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 2945
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
++P + +PL+NI + L C F G P+P + W++DG+++ + +
Sbjct: 5173 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5232
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581
Y+C+A N +G TSC V + +KP I S + K
Sbjct: 5233 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5292
Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639
++ K GD + G P P + W K+G +L +D++ + + T + + ++
Sbjct: 5293 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5352
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ A+N GT+S + L +
Sbjct: 5353 EGYFRCVATNEHGTASTKAELVI 5375
Score = 55.6 bits (128), Expect = 4e-07
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
D YT +Q + K +F + ++ +AP F + +G V+F+ + G
Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773
Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
P P+I WF + S+ + + +D + L I++V G TC N G AS
Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832
Query: 596 TELIVEAP 603
L V P
Sbjct: 833 GRLKVRVP 840
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
++P PL +P + + C+ G P P + W +DG +L + +A +
Sbjct: 5283 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5342
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
++C+A N+HG T +G + P + E+ K + +
Sbjct: 5343 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 5402
Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
G E V +I GIP P V WYK+G ++ D K T + + I
Sbjct: 5403 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 5462
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+Y++EA+N G++ E +L +
Sbjct: 5463 NASPDDEGEYSLEATNKLGSAKTEGSLNI 5491
Score = 53.6 bits (123), Expect = 1e-06
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
+ +++ + V G P P I W + P + G + + + ++ G
Sbjct: 5783 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 5842
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
Y A+N G A+ + I V+ T N PL +N+ T +++ RV P
Sbjct: 5843 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 5895
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
P + W + I S I DG + +I N DSG Y CVA N AG+++ V
Sbjct: 5896 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 5955
Query: 922 TIDVE 926
T++ E
Sbjct: 5956 TVEAE 5960
Score = 53.2 bits (122), Expect = 2e-06
Identities = 26/93 (27%), Positives = 49/93 (52%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+
Sbjct: 5867 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 5926
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
I + D+G ++CVA N AG A+++ + VEA
Sbjct: 5927 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 5959
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559
Q AP+F ++L+ K G + C V+G P+P + + F +T ++ S +
Sbjct: 2443 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 2502
Query: 560 YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612
+D N +VI ++ ED ++ +A N+ G A+ST+++ VEAP+ + G + T
Sbjct: 2503 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 2558
Score = 51.6 bits (118), Expect = 6e-06
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
L V E + + AP F+ L+ K T V EC+V G P+P+++W I +Q
Sbjct: 2339 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 2396
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604
+ + V + I G +TC+A+N G + + L V EAP+
Sbjct: 2397 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 2448
Score = 50.0 bits (114), Expect = 2e-05
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
S+ + +V GYP P ITW++ + + Y D+D + I V D G +TC+
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 585 AKNAAGFASST 595
A N G AS++
Sbjct: 623 ATNEYGQASTS 633
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAE---PPLFINRFQEITVKE 846
L+PK + KA ++ I A I P T++N + P+F R +++ +++
Sbjct: 6842 LEPKSHEQSTALLQKAPSATAIERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRK 6901
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
V+ +P P +TW +I+ ++ +T D N+ +I N + D G+Y C
Sbjct: 6902 NQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQD-NNVARLILNHAAPYDLGEYVC 6960
Query: 907 VASNSAGKSSHGARV 921
A N G R+
Sbjct: 6961 TAINEYGTDKSSCRL 6975
Score = 48.8 bits (111), Expect = 4e-05
Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 8/169 (4%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ P P+V W G LE++ I + + + +Y A N GT
Sbjct: 6911 VSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDK 6970
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNN--- 1711
L + PS+P P E+S ++ + I+W+ P LE Y +E N
Sbjct: 6971 SSCRLISGETPSRPGRP--EAELSSDTEIFIQWEAPEGPTYLEGITYRLEYRVAGPNDHG 7028
Query: 1712 -RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
WI V++ D E+ ++ L+ Y FRV AQN G S IV
Sbjct: 7029 DPWITVSE-KIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIV 7076
Score = 48.4 bits (110), Expect = 6e-05
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F + P + +G T++ + + G P P + W+ T ++ ++D ++ + + V T+
Sbjct: 1923 PAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEI-SNANGVYTMK 1981
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
I V + G CVA N AG S+ L V AP+
Sbjct: 1982 IHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPI 2016
Score = 48.0 bits (109), Expect = 7e-05
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
+E P R L + + E +V + V T V W +DG+ I P + F
Sbjct: 5394 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 5453
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
I L I N S DEGEYS ++ +A+ + ++ PP +
Sbjct: 5454 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 5513
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
+L+N+ V F+ + A V WF +G +I I++ + G L I D
Sbjct: 5514 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 5573
Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
L+DAGEY G++ +A+L V P ++ E + P T+ Y
Sbjct: 5574 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 5624
Score = 47.2 bits (107), Expect = 1e-04
Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 5/177 (2%)
Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
F P R+ +++ A P P W KI++ D+ A L
Sbjct: 6886 FAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARL 6945
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
+ D G Y N G + + PS PG+P + I I W+ PE
Sbjct: 6946 ILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPE 7005
Query: 1406 NTGNSTIIYYVVEYQEIDTTE----WISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
I Y +EY+ + WI+V + I +++L Y+FR A N
Sbjct: 7006 GPTYLEGITYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQN 7062
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T S PI V+ + + T +F+ + G+P P + W I++ S+
Sbjct: 1427 TVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKT 1486
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
+D V TL I E GT A+N+AG S +L VE
Sbjct: 1487 ED-VYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVE 1525
Score = 45.2 bits (102), Expect = 5e-04
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
+L V E P +++ P F +KLR G TVQ + V P W++ +++
Sbjct: 1329 ELKVLETP---KETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGNLLEDG 1383
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
++ +++N ++L+I +D+G T A N G + S+ +L V P
Sbjct: 1384 KNGVTIKNEENKSSLIIPNA--QDSGKITVEASNEVGSSESSAQLTVNPP 1431
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437
P+PP + P I E+ + + W + + YV+E +E+ +W ++ NI +
Sbjct: 5635 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 5694
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
++NL+ SY+FR A N ISD S
Sbjct: 5695 CKVRNLELGKSYQFRVRAENIYGISDPS 5722
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K T + P FV+ + T +V+F V G P P +TW+ + S++ ++
Sbjct: 1619 KVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVK 1678
Query: 560 YDDDNVATLV-IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
Y + T + I++ E GT A+N +G +T +L V+
Sbjct: 1679 YVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVD 1721
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ + + Y+ + + EC + A P P + W F+G+ + + N V IE D ++ +
Sbjct: 6888 PIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGK--ILESNDRVTIEQDNNV--A 6943
Query: 694 VLKITNVKKFQEGTYTVVAVNREG 717
L + + + G Y A+N G
Sbjct: 6944 RLILNHAAPYDLGEYVCTAINEYG 6967
Score = 39.9 bits (89), Expect = 0.019
Identities = 45/203 (22%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXX 1534
P + + L N++ +E+ G+P P V WY+DG+++ K T E
Sbjct: 5398 PRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIH 5457
Query: 1535 XXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE------------DIK 1581
Y A N G +T + I + I ++E +K
Sbjct: 5458 HLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 5517
Query: 1582 QKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSH 1639
KH + ++ G P PEV W+ NG K+ I + S + I +
Sbjct: 5518 NKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLED 5577
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ +Y A N+ G++S L V
Sbjct: 5578 AGEYVATAKNSHGSASSSAVLDV 5600
Score = 39.1 bits (87), Expect = 0.034
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++
Sbjct: 5762 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 5821
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
Y + TL I E+ G + C AKN G A
Sbjct: 5822 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 5855
Score = 37.9 bits (84), Expect = 0.078
Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGY-PRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
AP F + L + +G + ++ P+P+ITW + I +++ ++D
Sbjct: 1822 APTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLK 1881
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
L I + ED G T A++ G A + L
Sbjct: 1882 LSILQTKLEDKGRITIKAESEFGVAECSASL 1912
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472
E R A+ Y + + EAI L +G+ + +LD N W V+ K GWVP
Sbjct: 61 ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120
Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500
Y + Y Q++ +I+ + + ++
Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146
Score = 35.9 bits (79), Expect = 0.32
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 11/130 (8%)
Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDD----KITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
L + + I EI + PY +++ K+ TPP R + E T +TL
Sbjct: 5598 LDVTVPFLDSIKFNGEIDVT-PYLTEEYGFKKLNTASLPTPPD--RGPFIKEVTGHYLTL 5654
Query: 1885 KWTEPE-SNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA 1942
W + + P Y+IE + + K W+ + + V + + N++ FR+ A
Sbjct: 5655 SWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCK--VRNLELGKSYQFRVRA 5712
Query: 1943 ENTVGVSLPT 1952
EN G+S P+
Sbjct: 5713 ENIYGISDPS 5722
Score = 35.5 bits (78), Expect = 0.42
Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 4/87 (4%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYE---NRXXXX 1536
+P L+++ N+ C P PKVTW GK L++ + T E N
Sbjct: 6887 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 6946
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSC 1563
Y C A N++G ++SC
Sbjct: 6947 LNHAAPYDLGEYVCTAINEYGTDKSSC 6973
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1786 ITWFPSEKNGGS-PIIDYKVEIKQ-EGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYAR 1842
++W P+++ P + Y +EI++ K+W +++ L + +YQFR+ A
Sbjct: 5654 LSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAE 5713
Query: 1843 NEIGTSLP 1850
N G S P
Sbjct: 5714 NIYGISDP 5721
Score = 31.1 bits (67), Expect = 9.0
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 15/123 (12%)
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
A NE GT S ++ G+T + P +P + S++ + ++W PE Y
Sbjct: 6962 AINEYGTD---KSSCRLISGETPSRPGRPEAELSSDT---EIFIQWEAPEGPTYLEGITY 7015
Query: 1901 IIEFKTV----KGKSWTKIVTVGGSVHEHCI--ENIKEKDEIIFRISAENTVGVSLPTES 1954
+E++ G W +TV + + + +++ FR++A+N G+ LP+ S
Sbjct: 7016 RLEYRVAGPNDHGDPW---ITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLS 7072
Query: 1955 QSV 1957
+
Sbjct: 7073 SRI 7075
>AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated
protein 89, isoform a protein.
Length = 6632
Score = 266 bits (652), Expect = 1e-70
Identities = 306/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%)
Query: 460 KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506
+H+ E+KG + L+ D NN YT K +E + +L + FEK T+EE
Sbjct: 3625 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3683
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
+ P+F+E L+ +G TV EC+V PQI +F+ ++ Q Q+ +D
Sbjct: 3684 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3742
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620
L I+ ED G + C A N AG A++ +L VE ++D ++
Sbjct: 3743 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3802
Query: 621 XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ G P F + ++ V E +L+C++ P P I W +G+E+
Sbjct: 3803 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3862
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734
+ + D + L NV + G Y A N G A PI++ ++ K E
Sbjct: 3863 VRAEHKDDGTL---TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3919
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790
P ++P+K +V GE+ +L ++ G P+P++ W KN KP + ++ D T +T
Sbjct: 3920 PDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3979
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+ K+ D Y +A N G + +TV+EP + P F I VKE T
Sbjct: 3980 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 4035
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
K +V+ P + W+++ + + + ++ D LVI + ++ D G+Y+ S
Sbjct: 4036 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 4093
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968
N AG ++ +T+ + +K +G ++L + T KWY + ++
Sbjct: 4094 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 4153
Query: 969 GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018
+I+Q D G + ++ + ++T+ V K ++P
Sbjct: 4154 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 4213
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077
F + L D V + +LEVEI + DV W ++G+ IK K E G+ + +L I
Sbjct: 4214 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 4269
Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ D GEYS +E+ E V PEI++ L V +G ATF +++
Sbjct: 4270 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190
V+W+K+G EI + + DG L+I + ++DA +Y S + G++ +A LT
Sbjct: 4330 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 4387
Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
V+ PE + L+P A V++ V WYK I + +
Sbjct: 4388 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 4445
Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302
+ +L I DD +Y V+ DA V+ P IV + + +G
Sbjct: 4446 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 4505
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361
L V+ P+ +W N K I +P D L I + DA YK+
Sbjct: 4506 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416
L + G+ AD +T+ P +P I++ ++ ++I E E +G+ + +
Sbjct: 4565 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 4621
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+E+ ++K I K + L+ SS ++A K+ E
Sbjct: 4622 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4680
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531
KI T KPLK+ + E+ E + P+ V WY++G+++K + +
Sbjct: 4681 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4736
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587
+ YK + N GE E+S + +++ I ED Q G
Sbjct: 4737 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4794
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+ + I+G P +V W ++ N + I + T+ + I + +YT+E
Sbjct: 4795 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4853
Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671
N +G + + +V +KP G
Sbjct: 4854 VINESGKAKSDAKGEVDEKPEIVRG 4878
Score = 248 bits (607), Expect = 3e-65
Identities = 294/1183 (24%), Positives = 489/1183 (41%), Gaps = 110/1183 (9%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G+ + +VEG P+ + W++ T + SQ ++ ++ L I D G +
Sbjct: 4127 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 4185
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
V ST VE+ + +TV P+F K Q
Sbjct: 4186 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 4221
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V +G+ ++LE + P+ D+ W G+EI D + D+ L I + ++
Sbjct: 4222 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 4274
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y+V A N GE I K K P+++ L V+QGE+ + +V G P
Sbjct: 4275 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 4329
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
+ W KN K + TK +GD + +V+D Y + N G A++SA +TV+
Sbjct: 4330 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 4389
Query: 824 EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+ ++ P ++ TVK+ T +V + PV + WY+N + I P+ N
Sbjct: 4390 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 4447
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
DG + L I N + D+ DYK V SN AG + A +T+ + + VK L+ + E +
Sbjct: 4448 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 4504
Query: 943 GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000
GK +L+ +T+ KWY N KEI+ D + +G D K +
Sbjct: 4505 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
+ D++ +T L VK P+ I+ L+D V LE+E + V W ++G
Sbjct: 4565 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 4624
Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109
+ + K ++ K L I ++ V D G+Y + +E+ +A + + + P+I
Sbjct: 4625 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4684
Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166
+ L++Q + +G A F +E +V+W+K+G EI+ ++ I+ D K Q L I
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4743
Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220
+ DDA Y + G ++ +A LTV++ ++ E +V V+I
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4803
Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
E DV W + +VI + I D R LII D EYT +++ K+
Sbjct: 4804 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4862
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
+ K EV E P+IV I G D V+ A P +W N + IK H +
Sbjct: 4863 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4920
Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I K L I + + D YK+ L N G D +T++ KPN+L+I
Sbjct: 4921 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4973
Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
++ +EP+ G +I + QE+ + K K ++ +L SS
Sbjct: 4974 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 5032
Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503
+ A V +D E V +K K PT PLK+ E + + L C
Sbjct: 5033 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 5092
Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
G P P+V W +DG L+ T + + Y+ A N+ G
Sbjct: 5093 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGS 5152
Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611
+ C V + + KP I +K + GD+ + G+P P + W+ NG
Sbjct: 5153 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGI 5209
Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
++ D + + + I++++ A N GT
Sbjct: 5210 PIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 5252
Score = 246 bits (603), Expect = 1e-64
Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G+ ILL + P+ + W +KG E V + ++ Y L+I + +
Sbjct: 4124 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 4179
Query: 705 EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y VV + + S V K EK P + L V +G ++L ++ G P
Sbjct: 4180 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 4239
Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+ + W KN +K + G+ + + KD G Y++ A N G E+ A + V
Sbjct: 4240 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 4298
Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+A+P + ++ TVK+ T +V + PV + WY+N + I ++T N
Sbjct: 4299 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 4349
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935
DG + L I N E D+ DYK V SN AG + A +T+ D K V L
Sbjct: 4350 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 4407
Query: 936 KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
+ ++G+T + V KWY N KEI ++ D
Sbjct: 4408 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 4464
Query: 995 GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
K +V D ++S L VK ++ L+D EV + A+L+VE N + ++ W
Sbjct: 4465 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 4524
Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103
++G+ I P + +L I + D EY +L DE SC V +
Sbjct: 4525 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 4584
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160
P+II L++Q V+ G+ EIE + V+W+K+G E+ + I++ ID K
Sbjct: 4585 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4644
Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
L+I ++D G+Y EV G++ + +TVE P I F L + + +A
Sbjct: 4645 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4702
Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271
+VE + V WYK I+ +F + K L+I+ DD Y VL
Sbjct: 4703 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4762
Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+A+S+ +L V+ + KIV + + +G+ + V Q P+ + W+ ++ +I
Sbjct: 4763 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4821
Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
+ ID + L I + DAG Y + + N G A + + +KP
Sbjct: 4822 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4881
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447
+EI ++ + E + + + QEI + K I K + +I + +
Sbjct: 4882 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4939
Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
++ N D+S V+K ++ + LK++ E + +EL G
Sbjct: 4940 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4993
Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
+P+ + WY++G++LK ++ Y+ + ND GEV
Sbjct: 4994 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 5052
Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ VV ++ K S + K GD + I G P PEVIW K+G L+
Sbjct: 5053 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 5112
Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670
D + + T+ +RI+ K+S +Y + A N AG TS +VT+ + ++PSKP+
Sbjct: 5113 KDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPK 5172
Score = 218 bits (533), Expect = 3e-56
Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+E L G+ V + G P+P +TW+ I S D DD +TL
Sbjct: 2754 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2812
Query: 570 IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626
I P+ G C A+N AG S T +I S+ SE +
Sbjct: 2813 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2872
Query: 627 --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ + P P F K K +G + EC + WL G+EI
Sbjct: 2873 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2932
Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733
I V + + + L + NV G YT + N G EA+L ++ + K EK+
Sbjct: 2933 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2992
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791
P+ I L+ + E V+L +V+G P+P ++W +NK + +++ +S +TI
Sbjct: 2993 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 3052
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849
++ +G YT AEN+EG ++T A +TV+ E P+F Q E+++ EK
Sbjct: 3053 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 3103
Query: 850 IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901
+ L V +P P + +Y +E I+ S I D N +VI+ + E D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 3162
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960
YK +A+NS G ++ +++T VE F + L+K+ +E + + +E + + +W
Sbjct: 3163 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 3221
Query: 961 YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014
+ + K +S + E+ + E D G + E+S V +
Sbjct: 3222 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 3281
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070
++ P F+R+L EVK + A L V + V W +DG+ ++ + + G
Sbjct: 3282 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 3341
Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124
+ I++ + D G+Y+C + E+ T A VV+ +PPE + +L +V +
Sbjct: 3342 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 3401
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
T +++ + V WFKD + I N H IQ L I D D G YSC
Sbjct: 3402 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 3461
Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232
E G + TA + SI FT +L P + D +TV I +V W+K K
Sbjct: 3462 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 3520
Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
I+++ F TL I++ +D YTC +AK+T + V+ P
Sbjct: 3521 PINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 3580
Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346
V + Y +++G L+V + P+P +W + I +H + ++ S +L
Sbjct: 3581 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3640
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
IK N D G Y + N G
Sbjct: 3641 IKDTNNADFGKYTCQATNKAG 3661
Score = 209 bits (511), Expect = 1e-53
Identities = 292/1248 (23%), Positives = 486/1248 (38%), Gaps = 138/1248 (11%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP+FV+ L+P G + +VEG P P++ WF+ I + +
Sbjct: 3574 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 3633
Query: 564 NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
N + TLVI++ D G +TC A N AG E + E + + E
Sbjct: 3634 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3681
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
E + P F + K + EG ++LEC++ P I + + + +++ +
Sbjct: 3682 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3734
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
+ D ++ L I N KK G Y AVN G+A+ LKI+ K V +
Sbjct: 3735 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3791
Query: 743 SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781
+ + Q E+V +L + V + I CK +P +
Sbjct: 3792 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3851
Query: 782 SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824
+G ++ + KD+G TL +AEN G A T ++T+E
Sbjct: 3852 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEG 3911
Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883
+ + E P F+ + V T L +++ P PS+ WY+N E + PS+ + +N
Sbjct: 3912 APKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3971
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940
D L +TN + D +Y+C ASN G +T+ + +V F K L + +
Sbjct: 3972 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 4029
Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
+E +T EC+ S T KW+ + + H E +G D G
Sbjct: 4030 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 4088
Query: 998 KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052
+ + D + V +P K L D V + +L VE+ + V W +
Sbjct: 4089 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 4148
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106
E + + + KL I + + D G Y +L +S + E VTV +
Sbjct: 4149 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 4208
Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P L +Q V KG E+E+ V+W+K+G EI+ ++ + K +L
Sbjct: 4209 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 4266
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217
I D D GEYS N A + +N + + PE + LVP A
Sbjct: 4267 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 4322
Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273
V++ V WYK I D + T + +L I +D +Y V+ DA
Sbjct: 4323 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 4380
Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
S+ L V++ + P+IV +K+G T V + P +W N K I
Sbjct: 4381 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 4439
Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
K K + D S SL I + D YK+ + N+ G AD +T+ PG
Sbjct: 4440 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 4493
Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443
+ ++ + + + E I + +EI ++ K Q I +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 4553
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+ + ++ +E D + + + + P + K L++ I+L
Sbjct: 4554 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 4609
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
G P+ V WY++GK+L A A +N+ YK N+
Sbjct: 4610 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4668
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G +S + ++ P IT + +K + E +V P V WYKNG +++ +
Sbjct: 4669 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4725
Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
+ I K T + IK R + Y I NTAG SS ++T+K
Sbjct: 4726 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4773
Score = 202 bits (494), Expect = 2e-51
Identities = 265/1127 (23%), Positives = 450/1127 (39%), Gaps = 106/1127 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G +L+ P+ +I W G+EI P + + D L I +
Sbjct: 4502 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 4557
Query: 705 EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
Y VV + +G A L +K KEP ++I+ L+ +V G + L + G+P+
Sbjct: 4558 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 4616
Query: 764 PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
T+ W KN K + K + + D + + V+D G Y ++ N G A +S
Sbjct: 4617 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4675
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876
ITVE P +P + Q IT E V N P I WY+N + I P S
Sbjct: 4676 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4726
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
I + +LVI N + D+ YK V N+AG++ A++T+ K K + K
Sbjct: 4727 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4784
Query: 937 SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991
E + +G ++ E + +W + IS + I + +
Sbjct: 4785 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4844
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D G V ++ K + PE +R L++ E+ E D + +VE+++ V
Sbjct: 4845 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4904
Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105
W ++ + IKP + + +K G + +L I + D +Y +L + + C + + +
Sbjct: 4905 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963
Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159
P +I+ L++ V + ++++ +++W+K+G E++ + +
Sbjct: 4964 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 5023
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214
+ L I D G Y +GN K +++ V+ + F+ +T+
Sbjct: 5024 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 5083
Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267
LT++ I E +V W K V++ ++ T+ ++ TL IR + D +Y
Sbjct: 5084 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYR 5143
Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ +T+ KV V E PK V + G V + P+P +
Sbjct: 5144 VTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ 5203
Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
W +N IK + T + + LTI+ V D G K +N G D +
Sbjct: 5204 WFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 5262
Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437
G + L WD G+ I V+ EW K I T
Sbjct: 5263 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 5322
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480
T I+N + + R + E DI +ET Y+V ++E K +
Sbjct: 5323 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 5381
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535
+P + PL++ T + I L+C +P+ V WY+DG L+ T YE
Sbjct: 5382 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 5441
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587
Y+C+A N HG + TSC V ++ ++ V E K V G
Sbjct: 5442 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 5501
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646
D + + + G P PE+ WY+NG L N I T+ + + + + E S Y E
Sbjct: 5502 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685
A N T T+ V++ L +KP EG P + E+S SV++
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 5608
Score = 180 bits (439), Expect = 8e-45
Identities = 143/525 (27%), Positives = 224/525 (42%), Gaps = 45/525 (8%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+++ P FV KLR K +G + FEC+VEG+P P++ W ++PS DF++ YD
Sbjct: 642 EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622
A L IR+ P+D G +T +N G S EL V+A P +H
Sbjct: 702 T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
+ P F + DEG ++ + + P P+I W G+ + E +
Sbjct: 746 ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
E + C +L I +V + +G T NR G AS LK++ PP +PL+
Sbjct: 797 ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798
V++ +V+ V G P PT+T+ K +K + + I+I K
Sbjct: 852 DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+G KA+N G AE+ A +TVE+ EE+ P F+ ++ TVK V
Sbjct: 912 HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
NP P +TW+ N + + + N + +T +DS +G C A N+ G+
Sbjct: 972 NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029
Query: 919 AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
AR V + EK FV+ L ET + TV+ E + + WY +E+ D
Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
EI + D G I+ + + E S K T+
Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTV 1133
Score = 177 bits (430), Expect = 9e-44
Identities = 287/1251 (22%), Positives = 485/1251 (38%), Gaps = 155/1251 (12%)
Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
V+ L P G + + P+ +I W++ I PS Q D DN LVI +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 4552
Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
+DA + V + G + D +TV L
Sbjct: 4553 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 4586
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691
P K + Q V GS I LE P+ + W G+E+ ++ I+ D + Y
Sbjct: 4587 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4645
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750
VL+I + G Y V N G A+ + + EP ++PLK + +GE
Sbjct: 4646 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4698
Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ S + PR + W KN KP + DT ++K D Y +
Sbjct: 4699 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4757
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866
EN+ G AE+SA +TV++ + I + E V KG K+V V P + W
Sbjct: 4758 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4812
Query: 867 YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
R+ +IS + I + D L+I + D + D+G+Y N +GK+ A+ +D
Sbjct: 4813 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4870
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984
EK V+ L+ + E EG + + + S V KWY N +EI H E + G
Sbjct: 4871 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4929
Query: 985 XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
D G V+ D ++S L VVK + + + L+D +V+E L+V
Sbjct: 4930 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4989
Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095
++ + W ++G+ +KP + + FE++ + L I ++ D G Y +L D+
Sbjct: 4990 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 5049
Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143
+VV + ++ L++ +V +G+ T + + G+ V W KDG
Sbjct: 5050 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 5108
Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193
+Q + I ++ +DG L+I D G+Y N S C +T E+
Sbjct: 5109 VVLQKDDRITMRVALDGTAT-LRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQ 5167
Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244
PS F + L +P + + + V +P TL W+ I+ ++ TL
Sbjct: 5168 PSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ--WFLNGIPIKFDDRITLDDMADG 5225
Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
I DV++ KC E+ E C + + +PP+ +
Sbjct: 5226 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 5285
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354
RI G + + A P EW + K I+ HT + ++D + + I E +D
Sbjct: 5286 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 5344
Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
G+Y N G A+ + V IL+ + + + D+ N G
Sbjct: 5345 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 5401
Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458
+ V+ + W + ++TSIQ L N S +R A N
Sbjct: 5402 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 5461
Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
+ S + +E K + P K L ++ + + L C G P P++ WY
Sbjct: 5462 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 5521
Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
R+G+ L+ T + Y+C A N HG+ +T +Q
Sbjct: 5522 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 5581
Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+KP ++ +S+ + + + E VT G+P P V W K+G L
Sbjct: 5582 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 5637
Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
D + + + V +RIK Y A+N G+++ + +++ D
Sbjct: 5638 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5688
Score = 176 bits (429), Expect = 1e-43
Identities = 260/1229 (21%), Positives = 496/1229 (40%), Gaps = 133/1229 (10%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VAT 567
AP+F + L+ + ++ E +V G P + WF+ + + +M + + V T
Sbjct: 3188 APVFEQGLKKTSVKEKEEIKMEVKVGG-SAPDVEWFKDDKPVSEDGNHEMKKNPETGVFT 3246
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
LV+++ DAG +T A N AG T E EA ++
Sbjct: 3247 LVVKQAATTDAGKYTAKASNPAG----TAESSAEAEVTQS-------------------- 3282
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
LE PTF ++ V L + +P+P + WL G+ + D + +A
Sbjct: 3283 -LE--KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEG 3339
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
Y +K ++ G Y A N GEA + PP+ +E L + V+
Sbjct: 3340 SGSYSITIKDARLE--DSGKYACRATNPAGEAKTEANFAV-VKNLVPPEFVEKLSPLEVK 3396
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGV 802
+ ES LS +VVG P P++ W K++ P+ + ++ + S+TI ++ D G+
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQ-GDVGI 3455
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y+ +A N G A T+A + ++ PP F + + + V+E+ T+ L V PVP
Sbjct: 3456 YSCRARNEAGEALTTANFGIIR----DSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVP 3511
Query: 863 SITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
++ W+++++ I+ S ++ + L I E D G Y C A+N AG++ A
Sbjct: 3512 NVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGE-DVGVYTCKATNEAGEAKTTAN 3570
Query: 921 VTI--DVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ + ++E FV+ L K YE E+GK +++ + KW+ + I+ +D++ +I
Sbjct: 3571 MAVQEEIEAPLFVQGL-KPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIA-IDNQHVI 3628
Query: 977 Q---EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
+ E D G C ++ V + IP++ + Q E +V
Sbjct: 3629 EKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAE----EV 3684
Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
L +E ET V E D +++ K NK H + + +N + G++ +
Sbjct: 3685 KPLFIEPLKETFAV--EGDTVVLECKVNK-----ESHPQIKFFKNDQPVEIGQHMQLEVL 3737
Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
E ++T+ E + + + VN KA +L +IQF+ ++
Sbjct: 3738 EDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADL--------------KIQFAAKVE 3783
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
+ + +L ++ G++ VG++ + T + F + L V
Sbjct: 3784 EHVTDESGQL-------EEIGQFET-VGDTASSKTDT-GRGAPEF-VELLRSCTVTEKQQ 3833
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL 1271
A L ++ E + W K+ +E + + D TL T+ D EY C
Sbjct: 3834 AILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAE 3893
Query: 1272 DAKSTTKLKVEVV---EFPPKI----VDYEREYR---IKRGSDVTLLVDYQAFPQPNDEW 1321
+ + + ++ E PKI D+ + + + G L P+P+ +W
Sbjct: 3894 NEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKW 3953
Query: 1322 IVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADVEMNVTIL 1378
N + +K K ++D + LT+ + D Y+ N G +DV + V
Sbjct: 3954 YKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEP 4013
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQ 1437
+ +P + I E + +G + + + + + + ++ TQ
Sbjct: 4014 AQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQ 4073
Query: 1438 TS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTE 1494
I++ KT+ +R N+ ++++ + T + S T ++K L ++
Sbjct: 4074 RLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKGLTDVNVT 4125
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYK 1549
I L+ G P+ V WY+ + + +++ T E+ Y+
Sbjct: 4126 QGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYR 4184
Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIEGIPPPEV 1604
+ D VE+S V + K IS K Q G ++ IEG P +V
Sbjct: 4185 VVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEG-KPKDV 4242
Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYKNG+++++ K ++ + + I + + +Y++ A+N AG + + V
Sbjct: 4243 KWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSA 4300
Query: 1665 KPSKPEG--PVIMREISRESVTIEWKPPL 1691
KP G P +++ + ++ K P+
Sbjct: 4301 KPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Score = 171 bits (417), Expect = 4e-42
Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%)
Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563
MAP F+ K++ G + FEC V W + I+ ++ +
Sbjct: 2885 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2944
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
LV+ V PEDAG +TC+ +N AG + L V L +
Sbjct: 2945 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2993
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
P F + + ++LEC+++ P+P ++WL + I + S+
Sbjct: 2994 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 3040
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
+ES + + IT+ + +G YT +A N EG + L T + E P + L++
Sbjct: 3041 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 3095
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792
+ GE ++LS V G+P+P + + ++ K + TK +TH ++
Sbjct: 3096 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 3154
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+D Y A NS G A +++ IT + E P+F ++ +VKEK IK+
Sbjct: 3155 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 3208
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911
+V P + W+++++ +S + E + ++ + D+G Y ASN
Sbjct: 3209 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 3267
Query: 912 AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
AG +SS A VT +EK TFV+ L + E T+ + + S +W + + +
Sbjct: 3268 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 3327
Query: 969 GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020
I ++ D G C + + + VVK + PEF+
Sbjct: 3328 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 3387
Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077
KL EVKEK+ L V+ + + V W +D I N + +K+ + L I
Sbjct: 3388 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 3446
Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131
+ D G YSC R+E+ TA ++ +PPE +L+ +V + + T ++++T
Sbjct: 3447 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 3504
Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182
G + V WFKD I N HI +G L I +D G Y+C E G
Sbjct: 3505 VIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 3564
Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237
+K TA + V+E + F L + V A L V + + +V W+K I+
Sbjct: 3565 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 3623
Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286
+ + TL+I+ D +YTC + K T +LK+ F
Sbjct: 3624 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3683
Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344
P ++ +E G V L P ++ N + ++ +H + + + +
Sbjct: 3684 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3743
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
LTI+ + D G Y+ N G A+ ++ I
Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 169 bits (412), Expect = 1e-41
Identities = 255/1135 (22%), Positives = 433/1135 (38%), Gaps = 126/1135 (11%)
Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
TF K K Q + EG + P + W G+EI P+ + ++D Y V
Sbjct: 4684 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4741
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
+K N + TY +V N GEA L +K + ++++ L+ +V +G ++
Sbjct: 4742 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4799
Query: 755 SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P + W ++ + A + K D T+ + I+ +KD G YT++ N
Sbjct: 4800 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4857
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
G A++ A V+E E + + I + E V+ PV + WY+N+
Sbjct: 4858 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4909
Query: 871 EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
+ I P+ + G + EL I + D DYK V SN+AG A +T+ V
Sbjct: 4910 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4968
Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984
+ K + EE + V L+ + KWY N +E+ G E + G
Sbjct: 4969 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 5028
Query: 985 XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033
D G + ++ K + S +V K + P F+ L+D EV+E D+
Sbjct: 5029 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 5087
Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
L+ I E +V+WE+DG +++ L IR+ D G+Y +
Sbjct: 5088 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAK 5147
Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142
+E+ +A +VTV E P+ + L+ G+K F +++ ++WF +
Sbjct: 5148 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLN 5207
Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193
G I+F + I L DG L I D +D G C N T E +
Sbjct: 5208 GIPIKFDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 5266
Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244
LR P VP D + V P + T +V W+K IE T +
Sbjct: 5267 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 5325
Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290
+ V I I E D Y CV ++ A++ +VE++E + PKI
Sbjct: 5326 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 5385
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349
+ + G + L A P+ + W + ++ T + +A+L I
Sbjct: 5386 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 5445
Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
D G Y+ N G + +V + K + + W + G+
Sbjct: 5446 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 5502
Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455
S + V +W ++N +T +TS +L N S +R A
Sbjct: 5503 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 5562
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509
N + T + +T+ KP L +++ I+L C G+P
Sbjct: 5563 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 5622
Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561
P V W +DG L + ++ + N Y+C+A N++G T
Sbjct: 5623 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5682
Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
S VV Q P T+ D++ G + ++ P PE++WYK+G
Sbjct: 5683 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5740
Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I+ + + + + I Y + A+N +GT+ + T V P
Sbjct: 5741 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5795
Score = 156 bits (379), Expect = 1e-37
Identities = 258/1109 (23%), Positives = 438/1109 (39%), Gaps = 156/1109 (14%)
Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
F++ L+ + +G +F + PR + W++ IKP+ F + D LVI+
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4743
Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
+DA T+ V +N AG A S+ +L V+ I++G
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4785
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+ + Q V +G+ ++ E ++ PE D+ WL I N ++ + D Y
Sbjct: 4786 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4835
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
++ ++K G YTV +N G+A K E P+++ L+++ + +G+
Sbjct: 4836 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4889
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
+ +V P + W KN++ +K L K G + ++ D Y +
Sbjct: 4890 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4948
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N+ G ++SA +TV +P ++ +++ V+E ++L +V P I WY+
Sbjct: 4949 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 5002
Query: 869 NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926
N + + P ++ E+ E +T S+ D G Y+ V N G+ G+ V +
Sbjct: 5003 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 5062
Query: 927 K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975
K F+ L K E EEG + L+C + + W + + D +
Sbjct: 5063 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 5121
Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026
+G D+G + K++ S K T+ P+F+ L+
Sbjct: 5122 ALDG-TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 5180
Query: 1027 EVKEKDVAILEVEINSETADVV-WERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
D V++ + W +G IK + D G+ L IR+ D
Sbjct: 5181 AALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYC-LTIRDVREEDF 5239
Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128
G CI ++E+ T E TV E PP L ++++ G+ E
Sbjct: 5240 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 5298
Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
+ A V WFKDG +I+ + H ++ T+DG ++KI + D G Y C E+G
Sbjct: 5299 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 5357
Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
++ A VE P IN L E V L+ ++ V
Sbjct: 5358 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 5414
Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
WYK + D+ + TL I TE+D Y CV +A T V V+
Sbjct: 5415 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 5474
Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334
P + V E E RG TL P P +W N ++++ T
Sbjct: 5475 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 5534
Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386
+ S D S SLT+ + +D GIY+ EN G A V+M + +KP GK
Sbjct: 5535 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437
P ILE+ S+ N+ E + TG N ++ + I+ + EW + + Q
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490
I+N + +R A NE + S TT+ + + + T Q P + +
Sbjct: 5654 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5709
Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+ T + ++L C P P++ WY+DG
Sbjct: 5710 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5738
Score = 149 bits (361), Expect = 2e-35
Identities = 173/749 (23%), Positives = 292/749 (38%), Gaps = 93/749 (12%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S E + F+ L+ +G + +C + G P P++ W + +++ M
Sbjct: 5064 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 5123
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
D ATL IR D G + AKN AG A+S ++ V ++ G + +
Sbjct: 5124 DGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTV----TEQGEQPS---------- 5169
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
P F K G ++ +P+P + W G I D+ I++
Sbjct: 5170 ----------KPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITL 5219
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734
+D + YC L I +V++ GT +A N G + G + P
Sbjct: 5220 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
P+ PL + G+ + + V NP + W K+ K ++ T+ +K
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 794 --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846
P + D GVY A N G AET A VE E EE P ++ TV
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
I+L +V P S+ WY++ + + ++ + + N +E D G Y+C
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 5456
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956
VA+N+ G + V + V K K ++ + T + G + L+C +
Sbjct: 5457 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 5516
Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007
KWY N + + R +I+ D G+ +C K Q T+
Sbjct: 5517 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 5575
Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055
+ + +T P+FI +L D V +V LE ++ V W +DG +
Sbjct: 5576 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 5635
Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101
I+ + ++ E + +L I+N +VHDEG Y C+ +E+ +A V
Sbjct: 5636 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5695
Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158
PP ++ + + +G E ++ + W+KDG+ + S+ IQ+++ DG
Sbjct: 5696 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5755
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
L I C DD G Y N TA
Sbjct: 5756 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5783
Score = 143 bits (346), Expect = 1e-33
Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+ + AP L K G ++ C+V+ PR + W++ ++ + Y++D
Sbjct: 5377 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 5436
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
ATL I + ED G + CVA NA G +++ + V+ P + E
Sbjct: 5437 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 5483
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
G P F+K + D G L+C + P P+I W G+ +
Sbjct: 5484 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 5534
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733
IE+ CS L + EG Y A N G+A +L K K E +
Sbjct: 5535 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
PP+ I L M V G + L +V G P P++ W K+ P+ ++
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845
+ +K V DEG Y A N G A T + + +++ ++PP F + ++
Sbjct: 5654 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5713
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
E +KL +V +P+P + WY++ I++PS+ I + + + ++ D G Y+
Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5773
Query: 906 CVASNSAGKSSHGARVTI 923
+A+N +G + T+
Sbjct: 5774 VIATNPSGTAQDKGTATV 5791
Score = 141 bits (342), Expect = 4e-33
Identities = 270/1279 (21%), Positives = 483/1279 (37%), Gaps = 84/1279 (6%)
Query: 151 VTLEKSDLFDSQEDESKPD-VSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKI 209
+T E + S + E P+ V + P++ ++ KS K I E + K + +V EK
Sbjct: 1515 MTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKP 1574
Query: 210 NVPDDKETS-QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXX--X 266
P KE S + P S K+S+ +K K+ + E + P+
Sbjct: 1575 ASPTKKEKSPEKPASPTKKSE-NEVKSPTKKEKSPEKSVVEELKSPKEKSPEKADDKPKS 1633
Query: 267 XXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQ 326
E S K +KS K S KP +K K +K
Sbjct: 1634 PTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDDEVKSPTKKEKS 1693
Query: 327 VFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRK 386
+ P + + P S + V+S K+++ E++ KE PE+ K
Sbjct: 1694 PQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVK 1753
Query: 387 SSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLY 446
S +K ++ ++ +K +P + +PV++ D V + T + + + E
Sbjct: 1754 SPTKK-EKSPEKSAEEKPKSPTKKESSPVKM-ADDEV------KSPTKKEKSPEKVEEKP 1805
Query: 447 ILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQ 506
T + +K EE P + ++ T+ + EK + P EKP S
Sbjct: 1806 ASPTKKEKT--PEKSAAEELK-SPTKKEKSPSSPTKKTGDESKEKSPEKPE-EKPKSPTP 1861
Query: 507 SMAPIFVEKLRPKHTPDGST-----VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
+P K + +P+ + + +++ + + F +++ + + + + D
Sbjct: 1862 KKSPPGSPKKKKSKSPEAEKPPAPKLTRDLKLQTVNKTDLAHFE--VVVEHATECKWFLD 1919
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
+ T V +D F C + + F S T ++ + GS T
Sbjct: 1920 GKEITTAQGVTVSKDDQFEFRC-SIDTTMFGSGTVSVVAS---NAAGSVETKTELKVLET 1975
Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
E P F+ K + V +G + ++ ++A+ P W G ++ D
Sbjct: 1976 PK------ETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGN-LLEDGKNG 2026
Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
V I+++ + S L I N + G TV A N G + L + P V++
Sbjct: 2027 VTIKNEENK--SSLIIPNAQ--DSGKITVEASNEVGSSESSAQLTVNP-PSTTPIVVDGP 2081
Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
KS+ +++ E+ A + G P PT+ W N K V+ T + T + LK K E
Sbjct: 2082 KSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQ 2141
Query: 802 VYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-R 858
T+K A+NS G A + V E N + P F ++ + E ++ +
Sbjct: 2142 TGTVKVTAQNSAGQDSKQADLKV----EPNVKAPKFKSQLTDKVADEGEPLRWNLELDGP 2197
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
+P ++W N + ++ S+T+ G+ + I E+ SG A N+AG+
Sbjct: 2198 SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEM-SGTLTAKAKNAAGECET 2256
Query: 918 GARVTID--VEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHRE 974
A+VT++ +K FV+ Q T E T + + WY N K++ + +
Sbjct: 2257 SAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVK 2316
Query: 975 I--IQEGRXXXXXXXXXXXXDVGVIKCIV-----KDQETSTMLVVKET-IPEFIRKLQDF 1026
+ + E G I+ K Q T+ + V K+T +P+F + D
Sbjct: 2317 VKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDDR 2376
Query: 1027 EVKE-KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
+VKE +DV V W +GE + N +K G + I + G
Sbjct: 2377 QVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGE-HTIEISAVTPEQAG 2435
Query: 1086 EYSCIL------RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE--IELTKGDALV 1137
E SC + V V P L+++ + +G + + + K +
Sbjct: 2436 ELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKI 2495
Query: 1138 RWFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYS----CEVGNSKCTAILTVE 1192
W KDG EI H ++ + KL I L+D G + E G ++C+A L V
Sbjct: 2496 TWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVV 2555
Query: 1193 E--PSIN--FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDV 1248
+ P F + L +T + D T V WY ++ TE + +
Sbjct: 2556 KGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNAN 2615
Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDV 1305
T+ I T D + CV + + + P V++E + + G +
Sbjct: 2616 GVYTMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTL 2675
Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
L P+P W VN K +++ ++ K + + ++TIK + +G N
Sbjct: 2676 KLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINE 2735
Query: 1366 CGHADVEMNVTILDKPSPP 1384
G A E + +L + PP
Sbjct: 2736 YGKATSEATLLVLPRGEPP 2754
Score = 139 bits (337), Expect = 2e-32
Identities = 180/762 (23%), Positives = 288/762 (37%), Gaps = 105/762 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F L + P G + EC V+ P ++ WF+ I+ + ++ D +
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I D G + CVA N G A T+ + + +H E +
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAE--TQATYQVEILEHVEE------------EKRREYA 5382
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
I P K V+ G I L C++ AIP + W G + D S+ E D
Sbjct: 5383 PKINPPLEDKT----VNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG- 5437
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQVIEPLKS 743
+ L I + + G Y VA N G + + +K E E P + L
Sbjct: 5438 --TATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVD 5495
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKALPTKSDGDTHSITILKPKKVK 798
+ +G+S L V G+P P I W +N N P + T DG S+T+ +
Sbjct: 5496 LWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC-SLTV-NESTMS 5553
Query: 799 DEGVYTLKAENSEGIAETSAVITV-------EEPTEENAEPPLFINRFQEITVKEKGTIK 851
DEG+Y +AEN+ G A+T A V E+P + +PP FI +++V I
Sbjct: 5554 DEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVID 5613
Query: 852 LVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVAS 909
L +VT P PS+ W ++ +I S N + + +L I N D G Y+CVA+
Sbjct: 5614 LECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVH-DEGTYRCVAT 5672
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQT--SHTVST 958
N G ++ + V +D + V + T EG+ + LEC+ S
Sbjct: 5673 NENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEM 5732
Query: 959 KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVV 1012
WY + ++ D +I + D G+ + I + Q+ T V
Sbjct: 5733 VWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVK 5792
Query: 1013 K------------------ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
K P+ + L++ + EK L + + + + W +DG
Sbjct: 5793 KLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDG 5852
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVTVVELPP 1107
E + P E + +L + + + D G Y C+ + SC V + P
Sbjct: 5853 ERVFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKP 5912
Query: 1108 EII-------------TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152
I T L ++ G+ TFE L G+ ++W KDG E+ I
Sbjct: 5913 RDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFEC-LPFGNPFPSIKWLKDGLELFSDEKI 5971
Query: 1153 QL--TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
++ DG Q+L + D G + C N TA E
Sbjct: 5972 KMEAAADG-TQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Score = 133 bits (321), Expect = 2e-30
Identities = 185/819 (22%), Positives = 326/819 (39%), Gaps = 81/819 (9%)
Query: 936 KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989
K + ++G + + EC T V KW + KEI + + EG
Sbjct: 2894 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2953
Query: 990 XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036
D G CIV KD +T+ V++ + PEFI LQD K + +L
Sbjct: 2954 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 3013
Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
E ++ E V W D + I + E + ++ I ++ + +G+Y+CI +
Sbjct: 3014 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 3071
Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143
T++ +TV P LQN++++ G K + KG + K
Sbjct: 3072 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 3130
Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195
++I S+ I + D ++ I +D Y NS TA T VE P
Sbjct: 3131 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 3190
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253
L+ V + + V++ DV W+K K V ED + + TL
Sbjct: 3191 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 3247
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309
++++ D +YT + T + + EV + P V +K TL V
Sbjct: 3248 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 3307
Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P+ EW+ + + ++ H ++ S S S+TIK D+G Y R N G
Sbjct: 3308 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 3367
Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
A E N ++ PP K + LE+ + T + VE+ + DT
Sbjct: 3368 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 3422
Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
I ++ + QT++ +L N + + Y+ + + + TT + +I+++
Sbjct: 3423 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 3480
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534
P + L+ + E ++L G P P V W++D K + AK
Sbjct: 3481 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT 3540
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593
Y C A N+ GE +T+ + +Q++ + + +K + + G +
Sbjct: 3541 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 3600
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651
+EG P PEV W+K+G + D ++ I K + + + IK+ + KYT +A+N A
Sbjct: 3601 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3660
Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686
G LK+ ++K + E + E +E+ +E
Sbjct: 3661 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3699
Score = 131 bits (316), Expect = 6e-30
Identities = 145/606 (23%), Positives = 250/606 (41%), Gaps = 53/606 (8%)
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P PDI W ++ DE + + D + I V+ G YT +A N
Sbjct: 570 KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626
Query: 716 EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
G+AS ++ EKE PP + L+ ++G+ + +V G P P + W +++
Sbjct: 627 YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686
Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
P++ + DG T + I + + D GVYT+K +N G E+ A + V+ ++N
Sbjct: 687 PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
P F + + E ++ + +T +P P I W+ N + +S SE + + L
Sbjct: 746 VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948
I +V D G C SN G +S R+ + V TF K L+ +E TV+
Sbjct: 806 TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863
Query: 949 ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
E S T K+ +G + EI+ +G G I +++
Sbjct: 864 EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923
Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
E+ L V++ + P F++ ++D VK + A+ E + + +V W +G
Sbjct: 924 HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104
+ E H KL I S G C + R E+ V + +
Sbjct: 984 HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+
Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101
Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + ++DAGE NS + A LTV++ PEF L P + LTVE
Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPF-----APEFDLRPVS----LTVE 1152
Query: 1220 IPDETL 1225
E +
Sbjct: 1153 KGSEAV 1158
Score = 130 bits (313), Expect = 1e-29
Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K +++ P F + L G + +C V G P P+I W+R +++ +
Sbjct: 5477 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 5536
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
D +L + E D G + C A+NA G A + V+ L
Sbjct: 5537 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 5582
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ EG PP F + V G+ I LEC++ +P P + W G ++ D
Sbjct: 5583 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5640
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732
+ E+ +Y L+I N EGTY VA N G A+ +++ G
Sbjct: 5641 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5698
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789
+PP+ + + +G+ + L +V +P P + W K+ A+ T SD S+
Sbjct: 5699 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5754
Query: 790 ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832
T+L P V D+G+Y + A N G A+ TV++ P + A +
Sbjct: 5755 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5814
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890
P + + I + EK + +L + + +P P+I W+++ E + P + ++ DG EL
Sbjct: 5815 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5873
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
V+ + + D+G Y+CVA N+ G + V +
Sbjct: 5874 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5905
Score = 127 bits (306), Expect = 1e-28
Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+ + AP +E L P+ + + C+ G P+P I WF+ + P Q+ D
Sbjct: 5810 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5869
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
V LV+ +DAG + CVA+N G S+ T V D
Sbjct: 5870 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5915
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
+ I EG P F+ + G + EC P P I WL G E+ DE I +
Sbjct: 5916 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5975
Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731
+D L +++V EG + VA N G AS L I+ GE
Sbjct: 5976 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 732 KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782
E P++ L +M + +G V + G P PT+ W K+ + + K +
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834
+ H + I+ DEG Y+L+A N G A+T + + P +A+ PP
Sbjct: 6093 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 6151
Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893
F+ + + V V +P P + W+ N + I P I Q+ G + L+I
Sbjct: 6152 FVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 6211
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ E D+G+Y A NS G +S A + + V + +K
Sbjct: 6212 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 6249
Score = 121 bits (292), Expect = 5e-27
Identities = 224/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
+P+ L D YT E I++ + E P V L P+G
Sbjct: 4839 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4891
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
F+ +V P Q+ W++ IKP+ + L I +D + V NA
Sbjct: 4892 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4950
Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
AG S+ L V P I++G+ ++P+
Sbjct: 4951 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4983
Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
+ L+ ++ IP+ I W G+E+ PD + E L I + KK G Y
Sbjct: 4984 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 5040
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764
VV N +GE V+ +K+ + P + PLK V +G+ + L + G P P
Sbjct: 5041 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 5100
Query: 765 TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
+ W K+ ++ + DG T ++ I KK D G Y + A+N G A +
Sbjct: 5101 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSAKK-SDIGQYRVTAKNEAGSATSDCK 5158
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+TV E E+ ++P F+ + + +V P P++ W+ N I + I
Sbjct: 5159 VTVTEQGEQPSKPK-FVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRI 5217
Query: 880 T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928
T + N L I +V E D G KC+A N G + H D+
Sbjct: 5218 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985
G + +EC + T +W+ + K+I H EI
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030
D+GV C+ ++ ET V +E P+ L+D V
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
L ++++ A VVW +DG ++ + +E+ G L I +++ D G Y
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 5455
Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
C+ + SC+ V V + P L + ++G+ T + +T GD
Sbjct: 5456 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 5514
Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
++W+++G ++ I+ + DG L + + + D G Y CE G +K A
Sbjct: 5515 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 5573
Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233
V E+P ++ + P+FIL ++ L I E V W K
Sbjct: 5574 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 5632
Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283
+ + +F ++ K L I+ T D+ Y CV + +TTK V +
Sbjct: 5633 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5692
Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
PP+ + R G + L A P P W + I+ + S+
Sbjct: 5693 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5752
Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
A+L I D GIY++ N G A + T+ P G
Sbjct: 5753 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5799
Score = 116 bits (278), Expect = 2e-25
Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
EKP +E P F+ +L G+ + EC+V G P P + W + + F+
Sbjct: 5585 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5643
Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ V L I+ D GT+ CVA N G S+TT+ V D G V
Sbjct: 5644 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5698
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
PP F+ K EG + LEC++ A P P++ W G + P
Sbjct: 5699 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5744
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
+ I +++ D + L I + +G Y V+A N G A +K +G +
Sbjct: 5745 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5801
Query: 733 -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778
+ P+++EPL+++ + + +S L + G+P+PTI W K+ + P L
Sbjct: 5802 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5861
Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829
D ++ +D G Y AEN+ G A TS + V +P +
Sbjct: 5862 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5921
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+ P F K ++ NP PSI W ++ + E I + +
Sbjct: 5922 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5981
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944
+I + + + G ++CVA+N G +S A + I+ ++ + L + + E EE K
Sbjct: 5982 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 6037
Score = 114 bits (274), Expect = 7e-25
Identities = 135/593 (22%), Positives = 242/593 (40%), Gaps = 45/593 (7%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
P++ L+ Q VNK + A FE+ + +WF DG EI + + ++ D + + +
Sbjct: 1885 PKLTRDLKLQTVNKTDLAHFEVVVEHATEC-KWFLDGKEITTAQGVTVSKDDQFE----F 1939
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ET- 1224
C +D S V A +VE + L P+ P TD +E+ +T
Sbjct: 1940 RCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTV 1999
Query: 1225 -LDVT--------WYKKKSVIEDTEK-FTLISDVKKRTLIIRKCTEDDQC--EYTCVLLD 1272
+DV WY+ +++ED + T+ ++ K +LII + + E + +
Sbjct: 2000 QMDVIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGS 2059
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
++S+ +L V P +VD + IK FP P +W +N KI+++ +
Sbjct: 2060 SESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESR 2119
Query: 1333 H--TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
T + D + ++ K+E T G K+ +N+ G + ++ + P + L
Sbjct: 2120 TITTIKTEDVYTLKISNAKIEQT--GTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQL 2177
Query: 1391 --EIDSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKT 1445
++ + W+ E + T + +++ Q + ++ + V + +I K
Sbjct: 2178 TDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKP 2237
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
S A A N A E KV + P + +N T E ++ + I
Sbjct: 2238 EMSGTLTAKAKNA-----AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIV 2292
Query: 1506 GGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCI---AFNDHGEV 1559
G P P VTWY + KKL + K Y + I A N G+V
Sbjct: 2293 TGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKV 2352
Query: 1560 ETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
+ + + + +K + +N D +Q K G++ TA +EG P P V W NG +
Sbjct: 2353 QATAQLKVDKKTEVPKFTTNMDDRQV-KEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHP 2411
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL---KVYDKPS 1667
+T K+ I I + + + + EA+N G+ +V L KV D P+
Sbjct: 2412 NITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPT 2464
Score = 112 bits (269), Expect = 3e-24
Identities = 206/1012 (20%), Positives = 379/1012 (37%), Gaps = 71/1012 (7%)
Query: 726 KIKTGEKEP-PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKS 782
K EK P P++ LK V + + + +VV W + K + T S
Sbjct: 1875 KSPEAEKPPAPKLTRDLKLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVS 1932
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
D + G ++ A N+ G ET + V E +E +P F ++ +++
Sbjct: 1933 KDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPE-FTDKLRDM 1991
Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDS 901
V + T+++ +P+ WY+N ++ + +T + L+I N DS
Sbjct: 1992 EVTKGDTVQMDVIALHSPL--YKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DS 2046
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILECQTSH--TVST 958
G ASN G S A++T++ T V KS +E +T + S +
Sbjct: 2047 GKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTV 2106
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKE 1014
KW N+K + I+ G +K ++ Q++ L V+
Sbjct: 2107 KWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEP 2166
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEIIKPKKNKYDFEKRGH 1070
+ P+F +L D E + +E++ S +V W +G+ + +
Sbjct: 2167 NVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDG 2226
Query: 1071 IRKLYIRNTSVHDEGEYSCILRDES--C--TAEVTVV--ELPPEIITRLQNQKVNKGNKA 1124
+ I G + ++ + C +A+VTV PE + QN +
Sbjct: 2227 TYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESV 2286
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV- 1180
F +T K V W+ + ++ S +++ + K ++I ++ G E
Sbjct: 2287 KFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAE 2346
Query: 1181 ---GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
G + TA L V++ + FT + + V D T + V W
Sbjct: 2347 NVSGKVQATAQLKVDKKTEVPKFTTNMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGE 2405
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
+ T+ + T+ I T + CE T + K +L V+ V P
Sbjct: 2406 PVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTF 2465
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTI 1347
+ I G ++TL+ P+P W+ + I H K + S L+I
Sbjct: 2466 AKNLEDRLITEG-ELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSI 2524
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN- 1406
+ + D G ++ E+ G A+ ++ ++ K P KP + D + IN+ +
Sbjct: 2525 LQTKLEDKGRITIKAESEFGVAECSASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLEC 2582
Query: 1407 ----TGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460
TG+ T + + + Q + TE + N T I + + + + + A N+
Sbjct: 2583 KLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA- 2641
Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
+ S T KV+ ++ E L + T + ++L + G P+P V+WY +GK
Sbjct: 2642 -GEVS-TEGPLKVVAPIPVE---FETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGK 2696
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYK----CIAFNDHGEVETSCVVGIQQKPVITIS 1576
KL+ ++ + Y C A N++G+ + + + +
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 1577 NEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
E + + + G + + V G P P + WY N ++ N Y I T +KTS + I
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 1636 KRS-HSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVT 1684
H + +A N AG S + Y D S+ E E + +T
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLT 2868
Score = 111 bits (268), Expect = 4e-24
Identities = 145/628 (23%), Positives = 251/628 (39%), Gaps = 53/628 (8%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
Q S + +V G P P ITW K++ + + SD D + P +V D G YT
Sbjct: 561 QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N G A TSA V + E+ A PP F+ + ++ KE I V P P +
Sbjct: 621 CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
W +++ + PS +DG+ +L I + + D+G Y N G A + +
Sbjct: 680 VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738
Query: 924 -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
D +K Q + E +EG+ V + + + + W+ N K +S + + I
Sbjct: 739 ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798
Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031
E G++ C ++ S + V P F + L+D V+EK
Sbjct: 799 EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858
Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088
+ EV+++ + + G+ +K + + ++ I NTS+ HD GE
Sbjct: 859 STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917
Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137
++E TAE +TV + P + +++Q V G A FE + + V
Sbjct: 918 AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977
Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
WF +G ++ Q S +++ KL I AG C VG + A L V
Sbjct: 978 TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035
Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
P + P+F+ + + D + E+ E VTWY K ++ +++ +
Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301
+ I+ +D E V +++ + KL V+ F P+ +++
Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
GS+ P P EW VN + ++
Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVR 1181
Score = 108 bits (260), Expect = 4e-23
Identities = 120/526 (22%), Positives = 205/526 (38%), Gaps = 39/526 (7%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E PP F K + + EG I EC + PEP++ WL + + P + + +
Sbjct: 644 EAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ-- 701
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIV 746
+ L+I + + G YTV N G L ++ + P+ ++ +
Sbjct: 702 --TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVEC 759
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGVYT 804
+GE V + + G+P P I W N KP+ I IL K V +G+ T
Sbjct: 760 DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVT 819
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
+ N G A + V P PP F ++ TV+EK T+ V+ P P++
Sbjct: 820 CQGSNRLGSASCDGRLKVRVP----PAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTL 875
Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
T+ + + E + + + I N + G+ A N G + AR+T+
Sbjct: 876 TFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV 935
Query: 924 DVEK------VTFVKHLQ-KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ E+ TF+K ++ ++ +T E + + W+ N ++ +
Sbjct: 936 EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMD-QGSPGVK 994
Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----KETIPEFIRKLQDFE 1027
E G + C ++ ET LVV ++ P+F+ L D
Sbjct: 995 IEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKT 1054
Query: 1028 VKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
+ + EV + E V W GE +K E G I K+ I+N + D GE
Sbjct: 1055 ETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSI-KISIKNIKIEDAGE 1113
Query: 1087 YSCILRD----ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATF 1126
+ + + A++TV + P PE R + V KG++A F
Sbjct: 1114 IRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVF 1159
Score = 102 bits (244), Expect = 3e-21
Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%)
Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144
+ DES E+ P P+ IT++++ K KG+ A FE + TKG +W KDG
Sbjct: 2867 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2925
Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194
EI+ I++ T G + Q+L + + +DAG+Y+C V G C A LTV E
Sbjct: 2926 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2985
Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246
+ PEFI+ T + +E I + V+W + K++ +++ +
Sbjct: 2986 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 3045
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304
V++ T+ + + Q +YTC+ + + T+K + + V P + + G
Sbjct: 3046 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 3103
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356
+ L + PQP+ ++ S+ K + K T S I+ + + I ++ D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
YK N+ G A +T + +P + + + E + G++ + +
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
+ + + +K +T ++ T + ++ A A N +++S E +
Sbjct: 3223 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 3281
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527
++ PT + L + NE L+ GVP P V W +DG+ ++T AK
Sbjct: 3282 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 3337
Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586
Y C A N GE +T + + V E + + K
Sbjct: 3338 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 3397
Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644
+ ++ + G P P V W+K+ + D + I T + + I + ++ Y+
Sbjct: 3398 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 3457
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688
A N AG + + PE +R + RE T++ K
Sbjct: 3458 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 3502
Score = 97.1 bits (231), Expect = 1e-19
Identities = 113/461 (24%), Positives = 185/461 (40%), Gaps = 44/461 (9%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F + L K + STV FE V G+P P +T+ +K ++ D +
Sbjct: 844 PTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRIS 903
Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + G A+N G A S L VE + S
Sbjct: 904 IPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA------------------ 945
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
PTF K + Q V G + E + P P++ W G ++ D+ S ++ +
Sbjct: 946 -----PTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM--DQG-SPGVKIEA 997
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
H + L I + + GT A N G E +V+ +K+PP+ +E L
Sbjct: 998 HNHDHKLTIDSAQ--YAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTE 1055
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITI-LKPKKVKDEGVYT 804
+V+ +V G P+PT+TW + +K + SI I +K K++D G
Sbjct: 1056 TVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A NSEG ET A +TV++ P F R +TV++ A P+P+
Sbjct: 1116 AVATNSEGSDETKAKLTVQK----KPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTY 1171
Query: 865 TWYRNNEIISPSET---ITQN---FDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917
W N + + +T++ DG +I + T SE++ VA N+ G
Sbjct: 1172 EWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEET 1231
Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
GA++TI+ +K + V Q +E K + + + + +T
Sbjct: 1232 GAQLTIEPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 96.7 bits (230), Expect = 2e-19
Identities = 146/708 (20%), Positives = 276/708 (38%), Gaps = 67/708 (9%)
Query: 1046 DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100
D+ W +D ++ + +++ + ++ G + I V D G Y+C+ +E S +A
Sbjct: 578 DITWYKDDVQLHEDERHTFYSDEDGFFA-MTIDPVQVTDTGRYTCMATNEYGQASTSAFF 636
Query: 1101 TVVEL-----PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL 1154
V+++ PP +T+L++++ +G+ FE E+ + + W D ++ S+ +L
Sbjct: 637 RVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRL 696
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE-EPSINFTLRLPEFILVP 1209
DG+ KL+I D DD G Y+ ++ G+ + A L V+ +P N PEF
Sbjct: 697 QYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVA--PEFQATI 754
Query: 1210 ANTDA-------YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+ + +V D ++ W+ + ++EK IS+ L I+ T
Sbjct: 755 EYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHF 814
Query: 1263 QCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
TC L A +LKV V PP + ++ S V VD +P+P
Sbjct: 815 DGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPT 874
Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
+ + K +K + + S+ ++ D I + +N G A+ +
Sbjct: 875 LTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVA-KAQNEHGTAESRARL 933
Query: 1376 TI-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNI 1433
T+ ++ P L+ I D+ TG + V W I+ +
Sbjct: 934 TVEQEEEESRSAPTFLK----DIE---DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM 986
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEK-PLK- 1489
+ ++ N ++ + + A ++ + +P +K P K
Sbjct: 987 DQGSPGVKIEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKF 1046
Query: 1490 -NITTEPNEDIELTCIFG----GVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX 1540
I + E ++ T +F G P+P VTWY G++LK + ++
Sbjct: 1047 VEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNI 1106
Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGI 1599
+ +A N G ET + +Q+KP + + G E + +A GI
Sbjct: 1107 KIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGI 1166
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--------TIEASNTA 1651
P P W NG K+ + +E T+++++V L ++ Y ++ A NT
Sbjct: 1167 PLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTL 1226
Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
G L + +P K V +++S V E + + E T
Sbjct: 1227 GAEETGAQLTI--EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 90.6 bits (215), Expect = 1e-17
Identities = 86/357 (24%), Positives = 146/357 (40%), Gaps = 16/357 (4%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G PTF+K + + + EG L++ +L + P+P I WL G EI D + + E D
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQ 748
+ S+L+ K +G T+ A + G A L + G P + + + +
Sbjct: 2520 LKLSILQ---TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTE 2576
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-- 806
G+++ + G+P P + W + V A + + + +K V + +K
Sbjct: 2577 GDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCV 2636
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G T + V P P F + T +E T+KL A + P P ++W
Sbjct: 2637 AYNKAGEVSTEGPLKVVAPI-----PVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSW 2691
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--D 924
Y N + + S+ I + + + I ++ + SG C A N GK++ A + +
Sbjct: 2692 YVNGKKLEESQNIKIHSEKGTYTVTIKDITCDY-SGQVVCEAINEYGKATSEATLLVLPR 2750
Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGR 980
E F++ L K V T S WY N KEI D I+ + +
Sbjct: 2751 GEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDK 2807
Score = 88.6 bits (210), Expect = 4e-17
Identities = 75/271 (27%), Positives = 124/271 (45%), Gaps = 20/271 (7%)
Query: 653 LECRLVAI--PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
LEC+L+ P P + W + + E+ ++ + ++ +KI V G
Sbjct: 2580 LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVY----TMKIHGVTADMTGKIKC 2635
Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
VA N+ GE S LK+ P + L R+G+++ L A ++G P P ++W
Sbjct: 2636 VAYNKAGEVSTEGPLKVVA--PIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693
Query: 771 NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
N K ++ + S+ T+++TI K G +A N G A + A + V
Sbjct: 2694 NGKKLEESQNIKIHSEKGTYTVTI-KDITCDYSGQVVCEAINEYGKATSEATLLVLP--- 2749
Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDG 885
EPP F+ + + GT K+V +V T +P PS+TWY NN+ I S+ T D
Sbjct: 2750 -RGEPPDFLEWLSNVRART-GT-KVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDD 2806
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
+ L I + + ++ G+ C A N AG+ S
Sbjct: 2807 KTSTLTINSFNPDVHVGEIICKAENDAGEVS 2837
Score = 86.2 bits (204), Expect = 2e-16
Identities = 151/715 (21%), Positives = 276/715 (38%), Gaps = 68/715 (9%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P F+ KL+D E KE DV E E+ ++VW D + ++P + + + G KL
Sbjct: 648 PAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHD-FRLQYDGQTAKLE 706
Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PEIITRLQNQKVNKGNKAT 1125
IR+ D G Y+ +++E AE+ V P PE ++ + ++G +
Sbjct: 707 IRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVR 766
Query: 1126 FEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179
F+ +T GD + WF +G + S ++ + L I D G +C+
Sbjct: 767 FKSVIT-GDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNR 825
Query: 1180 VGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI---PDETLDVTWYKKKSV 1235
+G++ C L V P T P E V + V++ P+ TL T K+
Sbjct: 826 LGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELK 885
Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE-----F 1286
+ + D R I + E + A+S +L VE E
Sbjct: 886 NGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA 945
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASL 1345
P + D E + +K G + P P W +N K+ + K + L
Sbjct: 946 PTFLKDIE-DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHDHKL 1004
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-----DSSSINIC 1400
TI + AG R EN G + + + +L P +EI ++ +
Sbjct: 1005 TIDSAQY--AGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVV 1062
Query: 1401 WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458
++ E T+ +Y+ + +E+ ++ + ++ + + SI+N+K + RA A N
Sbjct: 1063 FEVRVEGEPKPTVTWYL-KGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATN- 1120
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
S+ S+ T+ K+ + K +P + ++T E + + G+P P W +
Sbjct: 1121 ---SEGSDETKA-KLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVN 1176
Query: 1519 GKKLKT----AKATYENRXXXXXXXXXXXXXXXY--------KCIAFNDHGEVETSCVVG 1566
G+K++ A+ T + Y +A N G ET +
Sbjct: 1177 GRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLT 1236
Query: 1567 IQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I+ +K + + +D+ +V E + ++ P L + K ++T E
Sbjct: 1237 IEPKKESVVVEKQDLSSS-EVQKE--IAQQVKEASPEATTTITMETSLTSTKTTTMSTTE 1293
Query: 1626 KTSVIR--IKELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
TS + E K S S S T+ + G + +++ + SK + +RE
Sbjct: 1294 VTSTVGGVTVETKESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVRE 1348
Score = 70.9 bits (166), Expect = 9e-12
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
+Y E + + + P+PDI W F+G +I S + L IT K
Sbjct: 6419 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 6478
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y A N G+A I++ + T P I+PL + + + + +V G P
Sbjct: 6479 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
P + W K +P+ + DG I+ +D G+Y+ A N G A TS
Sbjct: 6535 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 6594
Query: 820 ITVEEPTEEN 829
+TVE + N
Sbjct: 6595 VTVEAEGDYN 6604
Score = 60.5 bits (140), Expect = 1e-08
Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531
K+++ ++P L++ TT+ +E + L C G P+PKV+W D K + T E+
Sbjct: 2987 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 3046
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589
Y CIA N G +T + +Q + PV T ++++ K +G++
Sbjct: 3047 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 3103
Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641
+++ ++G P P V +Y K K+ + I + + R I ++ +
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y A+N+ G TS+ ++T KV + P +G +E + +E K +E
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
K E N+ K + + V T +++ + A NP G +E+
Sbjct: 3223 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 3273
Score = 57.6 bits (133), Expect = 9e-08
Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 3/149 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+Q P FVE L K +TV FE +VEG P+P +TW+ + +K S ++ D
Sbjct: 1038 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 1097
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXX 622
++ + I+ + EDAG VA N+ G + +L V+ P + V
Sbjct: 1098 SI-KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSE 1156
Query: 623 XXXADILEGIP-PTFSKKPKAQYVDEGSD 650
+ GIP PT+ + V +G +
Sbjct: 1157 AVFSAHAFGIPLPTYEWSVNGRKVRDGQE 1185
Score = 57.6 bits (133), Expect = 9e-08
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565
S+ P F +KLRP + T+ + V G P P + WF+ I D+
Sbjct: 3479 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGH 3538
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608
TL I++ ED G +TC A N AG A +T + V EAPL G
Sbjct: 3539 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 3585
Score = 57.2 bits (132), Expect = 1e-07
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 9/171 (5%)
Query: 1507 GVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P +TWY+D +L T + + Y C+A N++G+ T
Sbjct: 573 GYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQAST 632
Query: 1562 SC---VVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
S V+ ++++ ++ K K GD +EG P PE++W + L
Sbjct: 633 SAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSH 692
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
++ + +T+ + I++ + + YT++ N G+ + L V P K
Sbjct: 693 DFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDK 743
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
++P + +PL+NI + L C F G P+P + W++DG+++ + +
Sbjct: 5813 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5872
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581
Y+C+A N +G TSC V + +KP I S + K
Sbjct: 5873 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5932
Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639
++ K GD + G P P + W K+G +L +D++ + + T + + ++
Sbjct: 5933 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5992
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ A+N GT+S + L +
Sbjct: 5993 EGYFRCVATNEHGTASTKAELVI 6015
Score = 55.6 bits (128), Expect = 4e-07
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
D YT +Q + K +F + ++ +AP F + +G V+F+ + G
Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773
Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
P P+I WF + S+ + + +D + L I++V G TC N G AS
Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832
Query: 596 TELIVEAP 603
L V P
Sbjct: 833 GRLKVRVP 840
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
++P PL +P + + C+ G P P + W +DG +L + +A +
Sbjct: 5923 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5982
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
++C+A N+HG T +G + P + E+ K + +
Sbjct: 5983 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 6042
Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
G E V +I GIP P V WYK+G ++ D K T + + I
Sbjct: 6043 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 6102
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+Y++EA+N G++ E +L +
Sbjct: 6103 NASPDDEGEYSLEATNKLGSAKTEGSLNI 6131
Score = 53.6 bits (123), Expect = 1e-06
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
+ +++ + V G P P I W + P + G + + + ++ G
Sbjct: 6423 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 6482
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
Y A+N G A+ + I V+ T N PL +N+ T +++ RV P
Sbjct: 6483 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 6535
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
P + W + I S I DG + +I N DSG Y CVA N AG+++ V
Sbjct: 6536 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 6595
Query: 922 TIDVE 926
T++ E
Sbjct: 6596 TVEAE 6600
Score = 53.2 bits (122), Expect = 2e-06
Identities = 26/93 (27%), Positives = 49/93 (52%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
I + D+G ++CVA N AG A+++ + VEA
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 6599
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559
Q AP+F ++L+ K G + C V+G P+P + + F +T ++ S +
Sbjct: 3083 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 3142
Query: 560 YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612
+D N +VI ++ ED ++ +A N+ G A+ST+++ VEAP+ + G + T
Sbjct: 3143 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 3198
Score = 51.6 bits (118), Expect = 6e-06
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
L V E + + AP F+ L+ K T V EC+V G P+P+++W I +Q
Sbjct: 2979 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 3036
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604
+ + V + I G +TC+A+N G + + L V EAP+
Sbjct: 3037 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 3088
Score = 50.0 bits (114), Expect = 2e-05
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
S+ + +V GYP P ITW++ + + Y D+D + I V D G +TC+
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 585 AKNAAGFASST 595
A N G AS++
Sbjct: 623 ATNEYGQASTS 633
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/235 (20%), Positives = 88/235 (37%), Gaps = 12/235 (5%)
Query: 1466 ETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
ET KV++ K + P L+++ + +++ I + P WY++G L+
Sbjct: 1965 ETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLED 2022
Query: 1525 AK--ATYENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNE 1578
K T +N + A N+ G E+S + + P++ +
Sbjct: 2023 GKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPK 2082
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ K E+ T I G P P V W N +E + E ++I K
Sbjct: 2083 SVTIKETETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIE 2140
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692
+ + A N+AG S + LKV P+ + +++ E + W LD
Sbjct: 2141 QTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 2195
Score = 48.0 bits (109), Expect = 7e-05
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
+E P R L + + E +V + V T V W +DG+ I P + F
Sbjct: 6034 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 6093
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
I L I N S DEGEYS ++ +A+ + ++ PP +
Sbjct: 6094 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 6153
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
+L+N+ V F+ + A V WF +G +I I++ + G L I D
Sbjct: 6154 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 6213
Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
L+DAGEY G++ +A+L V P ++ E + P T+ Y
Sbjct: 6214 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 6264
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437
P+PP + P I E+ + + W + + YV+E +E+ +W ++ NI +
Sbjct: 6275 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 6334
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
++NL+ SY+FR A N ISD S
Sbjct: 6335 CKVRNLELGKSYQFRVRAENIYGISDPS 6362
Score = 39.9 bits (89), Expect = 0.019
Identities = 45/203 (22%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXX 1534
P + + L N++ +E+ G+P P V WY+DG+++ K T E
Sbjct: 6038 PRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIH 6097
Query: 1535 XXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE------------DIK 1581
Y A N G +T + I + I ++E +K
Sbjct: 6098 HLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 6157
Query: 1582 QKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSH 1639
KH + ++ G P PEV W+ NG K+ I + S + I +
Sbjct: 6158 NKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLED 6217
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ +Y A N+ G++S L V
Sbjct: 6218 AGEYVATAKNSHGSASSSAVLDV 6240
Score = 39.1 bits (87), Expect = 0.034
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++
Sbjct: 6402 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 6461
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
Y + TL I E+ G + C AKN G A
Sbjct: 6462 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 6495
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472
E R A+ Y + + EAI L +G+ + +LD N W V+ K GWVP
Sbjct: 61 ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120
Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500
Y + Y Q++ +I+ + + ++
Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
+ G P P++ WYK+ +L D+ + + E + I ++ + + +YT A+N G +
Sbjct: 571 VTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQA 630
Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678
S +V + P + ++
Sbjct: 631 STSAFFRVLKVEKEAAPPAFVTKL 654
Score = 35.9 bits (79), Expect = 0.32
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 11/130 (8%)
Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDD----KITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
L + + I EI + PY +++ K+ TPP R + E T +TL
Sbjct: 6238 LDVTVPFLDSIKFNGEIDVT-PYLTEEYGFKKLNTASLPTPPD--RGPFIKEVTGHYLTL 6294
Query: 1885 KWTEPE-SNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA 1942
W + + P Y+IE + + K W+ + + V + + N++ FR+ A
Sbjct: 6295 SWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCK--VRNLELGKSYQFRVRA 6352
Query: 1943 ENTVGVSLPT 1952
EN G+S P+
Sbjct: 6353 ENIYGISDPS 6362
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1786 ITWFPSEKNGGS-PIIDYKVEIKQ-EGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYAR 1842
++W P+++ P + Y +EI++ K+W +++ L + +YQFR+ A
Sbjct: 6294 LSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAE 6353
Query: 1843 NEIGTSLP 1850
N G S P
Sbjct: 6354 NIYGISDP 6361
Score = 31.9 bits (69), Expect = 5.2
Identities = 35/193 (18%), Positives = 66/193 (34%), Gaps = 5/193 (2%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYC 692
P F +P + V++GS+ + IP P W G ++ E V +
Sbjct: 1140 PEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGA 1199
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S+L I + E + ++V E T E + V+ + + + +
Sbjct: 1200 SILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKESVVVEKQDLSSSEVQKE 1259
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYTLKAE 808
I +P T T T + T+ ++ K+ + E T+
Sbjct: 1260 IAQQVKEASPEATTTITMETSLTSTKTTTMSTTEVTSTVGGVTVETKESESESATTVIGG 1319
Query: 809 NSEGIAETSAVIT 821
S G+ E S ++
Sbjct: 1320 GSGGVTEGSISVS 1332
Score = 31.5 bits (68), Expect = 6.8
Identities = 48/230 (20%), Positives = 83/230 (36%), Gaps = 16/230 (6%)
Query: 180 EAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLT-----PIK 234
E ++ ESE+ ++TS + PEK+ D+K S T + +T P+K
Sbjct: 1508 ETTMTTEMTHESEE--SRTSVKKEKTPEKV---DEKPKSPTKKDKSPEKSITEEIKSPVK 1562
Query: 235 IERKEMEVSTPQHAETVD--GPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSW 292
E+ +V + T P+ T K P+ + +K
Sbjct: 1563 KEKSPEKVEEKPASPTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPKEK 1622
Query: 293 PPESI--KPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYED 350
PE KP + ++K K +K + P + P +D
Sbjct: 1623 SPEKADDKPKSPTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDD 1682
Query: 351 IVES--KKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDE 398
V+S KK+++ E++ KE PE+ + KS +K E +E
Sbjct: 1683 EVKSPTKKEKSPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEE 1732
>AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated
protein 89, isoform g protein.
Length = 7122
Score = 266 bits (652), Expect = 1e-70
Identities = 306/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%)
Query: 460 KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506
+H+ E+KG + L+ D NN YT K +E + +L + FEK T+EE
Sbjct: 3625 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3683
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
+ P+F+E L+ +G TV EC+V PQI +F+ ++ Q Q+ +D
Sbjct: 3684 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3742
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620
L I+ ED G + C A N AG A++ +L VE ++D ++
Sbjct: 3743 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3802
Query: 621 XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ G P F + ++ V E +L+C++ P P I W +G+E+
Sbjct: 3803 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3862
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734
+ + D + L NV + G Y A N G A PI++ ++ K E
Sbjct: 3863 VRAEHKDDGTL---TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3919
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790
P ++P+K +V GE+ +L ++ G P+P++ W KN KP + ++ D T +T
Sbjct: 3920 PDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3979
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+ K+ D Y +A N G + +TV+EP + P F I VKE T
Sbjct: 3980 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 4035
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
K +V+ P + W+++ + + + ++ D LVI + ++ D G+Y+ S
Sbjct: 4036 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 4093
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968
N AG ++ +T+ + +K +G ++L + T KWY + ++
Sbjct: 4094 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 4153
Query: 969 GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018
+I+Q D G + ++ + ++T+ V K ++P
Sbjct: 4154 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 4213
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077
F + L D V + +LEVEI + DV W ++G+ IK K E G+ + +L I
Sbjct: 4214 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 4269
Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ D GEYS +E+ E V PEI++ L V +G ATF +++
Sbjct: 4270 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190
V+W+K+G EI + + DG L+I + ++DA +Y S + G++ +A LT
Sbjct: 4330 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 4387
Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
V+ PE + L+P A V++ V WYK I + +
Sbjct: 4388 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 4445
Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302
+ +L I DD +Y V+ DA V+ P IV + + +G
Sbjct: 4446 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 4505
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361
L V+ P+ +W N K I +P D L I + DA YK+
Sbjct: 4506 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416
L + G+ AD +T+ P +P I++ ++ ++I E E +G+ + +
Sbjct: 4565 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 4621
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+E+ ++K I K + L+ SS ++A K+ E
Sbjct: 4622 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4680
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531
KI T KPLK+ + E+ E + P+ V WY++G+++K + +
Sbjct: 4681 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4736
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587
+ YK + N GE E+S + +++ I ED Q G
Sbjct: 4737 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4794
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+ + I+G P +V W ++ N + I + T+ + I + +YT+E
Sbjct: 4795 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4853
Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671
N +G + + +V +KP G
Sbjct: 4854 VINESGKAKSDAKGEVDEKPEIVRG 4878
Score = 248 bits (607), Expect = 3e-65
Identities = 294/1183 (24%), Positives = 489/1183 (41%), Gaps = 110/1183 (9%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G+ + +VEG P+ + W++ T + SQ ++ ++ L I D G +
Sbjct: 4127 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 4185
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
V ST VE+ + +TV P+F K Q
Sbjct: 4186 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 4221
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V +G+ ++LE + P+ D+ W G+EI D + D+ L I + ++
Sbjct: 4222 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 4274
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y+V A N GE I K K P+++ L V+QGE+ + +V G P
Sbjct: 4275 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 4329
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
+ W KN K + TK +GD + +V+D Y + N G A++SA +TV+
Sbjct: 4330 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 4389
Query: 824 EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+ ++ P ++ TVK+ T +V + PV + WY+N + I P+ N
Sbjct: 4390 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 4447
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
DG + L I N + D+ DYK V SN AG + A +T+ + + VK L+ + E +
Sbjct: 4448 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 4504
Query: 943 GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000
GK +L+ +T+ KWY N KEI+ D + +G D K +
Sbjct: 4505 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
+ D++ +T L VK P+ I+ L+D V LE+E + V W ++G
Sbjct: 4565 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 4624
Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109
+ + K ++ K L I ++ V D G+Y + +E+ +A + + + P+I
Sbjct: 4625 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4684
Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166
+ L++Q + +G A F +E +V+W+K+G EI+ ++ I+ D K Q L I
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4743
Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220
+ DDA Y + G ++ +A LTV++ ++ E +V V+I
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4803
Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
E DV W + +VI + I D R LII D EYT +++ K+
Sbjct: 4804 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4862
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
+ K EV E P+IV I G D V+ A P +W N + IK H +
Sbjct: 4863 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4920
Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I K L I + + D YK+ L N G D +T++ KPN+L+I
Sbjct: 4921 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4973
Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
++ +EP+ G +I + QE+ + K K ++ +L SS
Sbjct: 4974 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 5032
Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503
+ A V +D E V +K K PT PLK+ E + + L C
Sbjct: 5033 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 5092
Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
G P P+V W +DG L+ T + + Y+ A N+ G
Sbjct: 5093 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGS 5152
Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611
+ C V + + KP I +K + GD+ + G+P P + W+ NG
Sbjct: 5153 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGI 5209
Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
++ D + + + I++++ A N GT
Sbjct: 5210 PIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 5252
Score = 246 bits (603), Expect = 1e-64
Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G+ ILL + P+ + W +KG E V + ++ Y L+I + +
Sbjct: 4124 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 4179
Query: 705 EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y VV + + S V K EK P + L V +G ++L ++ G P
Sbjct: 4180 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 4239
Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+ + W KN +K + G+ + + KD G Y++ A N G E+ A + V
Sbjct: 4240 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 4298
Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+A+P + ++ TVK+ T +V + PV + WY+N + I ++T N
Sbjct: 4299 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 4349
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935
DG + L I N E D+ DYK V SN AG + A +T+ D K V L
Sbjct: 4350 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 4407
Query: 936 KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
+ ++G+T + V KWY N KEI ++ D
Sbjct: 4408 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 4464
Query: 995 GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
K +V D ++S L VK ++ L+D EV + A+L+VE N + ++ W
Sbjct: 4465 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 4524
Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103
++G+ I P + +L I + D EY +L DE SC V +
Sbjct: 4525 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 4584
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160
P+II L++Q V+ G+ EIE + V+W+K+G E+ + I++ ID K
Sbjct: 4585 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4644
Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
L+I ++D G+Y EV G++ + +TVE P I F L + + +A
Sbjct: 4645 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4702
Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271
+VE + V WYK I+ +F + K L+I+ DD Y VL
Sbjct: 4703 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4762
Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+A+S+ +L V+ + KIV + + +G+ + V Q P+ + W+ ++ +I
Sbjct: 4763 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4821
Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
+ ID + L I + DAG Y + + N G A + + +KP
Sbjct: 4822 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4881
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447
+EI ++ + E + + + QEI + K I K + +I + +
Sbjct: 4882 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4939
Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
++ N D+S V+K ++ + LK++ E + +EL G
Sbjct: 4940 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4993
Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
+P+ + WY++G++LK ++ Y+ + ND GEV
Sbjct: 4994 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 5052
Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ VV ++ K S + K GD + I G P PEVIW K+G L+
Sbjct: 5053 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 5112
Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670
D + + T+ +RI+ K+S +Y + A N AG TS +VT+ + ++PSKP+
Sbjct: 5113 KDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPK 5172
Score = 218 bits (533), Expect = 3e-56
Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+E L G+ V + G P+P +TW+ I S D DD +TL
Sbjct: 2754 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2812
Query: 570 IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626
I P+ G C A+N AG S T +I S+ SE +
Sbjct: 2813 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2872
Query: 627 --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ + P P F K K +G + EC + WL G+EI
Sbjct: 2873 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2932
Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733
I V + + + L + NV G YT + N G EA+L ++ + K EK+
Sbjct: 2933 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2992
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791
P+ I L+ + E V+L +V+G P+P ++W +NK + +++ +S +TI
Sbjct: 2993 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 3052
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849
++ +G YT AEN+EG ++T A +TV+ E P+F Q E+++ EK
Sbjct: 3053 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 3103
Query: 850 IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901
+ L V +P P + +Y +E I+ S I D N +VI+ + E D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 3162
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960
YK +A+NS G ++ +++T VE F + L+K+ +E + + +E + + +W
Sbjct: 3163 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 3221
Query: 961 YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014
+ + K +S + E+ + E D G + E+S V +
Sbjct: 3222 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 3281
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070
++ P F+R+L EVK + A L V + V W +DG+ ++ + + G
Sbjct: 3282 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 3341
Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124
+ I++ + D G+Y+C + E+ T A VV+ +PPE + +L +V +
Sbjct: 3342 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 3401
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
T +++ + V WFKD + I N H IQ L I D D G YSC
Sbjct: 3402 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 3461
Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232
E G + TA + SI FT +L P + D +TV I +V W+K K
Sbjct: 3462 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 3520
Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
I+++ F TL I++ +D YTC +AK+T + V+ P
Sbjct: 3521 PINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 3580
Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346
V + Y +++G L+V + P+P +W + I +H + ++ S +L
Sbjct: 3581 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3640
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
IK N D G Y + N G
Sbjct: 3641 IKDTNNADFGKYTCQATNKAG 3661
Score = 209 bits (511), Expect = 1e-53
Identities = 292/1248 (23%), Positives = 486/1248 (38%), Gaps = 138/1248 (11%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP+FV+ L+P G + +VEG P P++ WF+ I + +
Sbjct: 3574 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 3633
Query: 564 NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
N + TLVI++ D G +TC A N AG E + E + + E
Sbjct: 3634 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3681
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
E + P F + K + EG ++LEC++ P I + + + +++ +
Sbjct: 3682 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3734
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
+ D ++ L I N KK G Y AVN G+A+ LKI+ K V +
Sbjct: 3735 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3791
Query: 743 SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781
+ + Q E+V +L + V + I CK +P +
Sbjct: 3792 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3851
Query: 782 SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824
+G ++ + KD+G TL +AEN G A T ++T+E
Sbjct: 3852 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEG 3911
Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883
+ + E P F+ + V T L +++ P PS+ WY+N E + PS+ + +N
Sbjct: 3912 APKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3971
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940
D L +TN + D +Y+C ASN G +T+ + +V F K L + +
Sbjct: 3972 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 4029
Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
+E +T EC+ S T KW+ + + H E +G D G
Sbjct: 4030 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 4088
Query: 998 KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052
+ + D + V +P K L D V + +L VE+ + V W +
Sbjct: 4089 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 4148
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106
E + + + KL I + + D G Y +L +S + E VTV +
Sbjct: 4149 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 4208
Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P L +Q V KG E+E+ V+W+K+G EI+ ++ + K +L
Sbjct: 4209 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 4266
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217
I D D GEYS N A + +N + + PE + LVP A
Sbjct: 4267 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 4322
Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273
V++ V WYK I D + T + +L I +D +Y V+ DA
Sbjct: 4323 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 4380
Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
S+ L V++ + P+IV +K+G T V + P +W N K I
Sbjct: 4381 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 4439
Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
K K + D S SL I + D YK+ + N+ G AD +T+ PG
Sbjct: 4440 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 4493
Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443
+ ++ + + + E I + +EI ++ K Q I +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 4553
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+ + ++ +E D + + + + P + K L++ I+L
Sbjct: 4554 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 4609
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
G P+ V WY++GK+L A A +N+ YK N+
Sbjct: 4610 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4668
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G +S + ++ P IT + +K + E +V P V WYKNG +++ +
Sbjct: 4669 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4725
Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
+ I K T + IK R + Y I NTAG SS ++T+K
Sbjct: 4726 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4773
Score = 202 bits (494), Expect = 2e-51
Identities = 265/1127 (23%), Positives = 450/1127 (39%), Gaps = 106/1127 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G +L+ P+ +I W G+EI P + + D L I +
Sbjct: 4502 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 4557
Query: 705 EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
Y VV + +G A L +K KEP ++I+ L+ +V G + L + G+P+
Sbjct: 4558 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 4616
Query: 764 PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
T+ W KN K + K + + D + + V+D G Y ++ N G A +S
Sbjct: 4617 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4675
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876
ITVE P +P + Q IT E V N P I WY+N + I P S
Sbjct: 4676 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4726
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
I + +LVI N + D+ YK V N+AG++ A++T+ K K + K
Sbjct: 4727 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4784
Query: 937 SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991
E + +G ++ E + +W + IS + I + +
Sbjct: 4785 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4844
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D G V ++ K + PE +R L++ E+ E D + +VE+++ V
Sbjct: 4845 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4904
Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105
W ++ + IKP + + +K G + +L I + D +Y +L + + C + + +
Sbjct: 4905 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963
Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159
P +I+ L++ V + ++++ +++W+K+G E++ + +
Sbjct: 4964 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 5023
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214
+ L I D G Y +GN K +++ V+ + F+ +T+
Sbjct: 5024 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 5083
Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267
LT++ I E +V W K V++ ++ T+ ++ TL IR + D +Y
Sbjct: 5084 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYR 5143
Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ +T+ KV V E PK V + G V + P+P +
Sbjct: 5144 VTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ 5203
Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
W +N IK + T + + LTI+ V D G K +N G D +
Sbjct: 5204 WFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 5262
Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437
G + L WD G+ I V+ EW K I T
Sbjct: 5263 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 5322
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480
T I+N + + R + E DI +ET Y+V ++E K +
Sbjct: 5323 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 5381
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535
+P + PL++ T + I L+C +P+ V WY+DG L+ T YE
Sbjct: 5382 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 5441
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587
Y+C+A N HG + TSC V ++ ++ V E K V G
Sbjct: 5442 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 5501
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646
D + + + G P PE+ WY+NG L N I T+ + + + + E S Y E
Sbjct: 5502 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685
A N T T+ V++ L +KP EG P + E+S SV++
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 5608
Score = 180 bits (439), Expect = 8e-45
Identities = 143/525 (27%), Positives = 224/525 (42%), Gaps = 45/525 (8%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+++ P FV KLR K +G + FEC+VEG+P P++ W ++PS DF++ YD
Sbjct: 642 EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622
A L IR+ P+D G +T +N G S EL V+A P +H
Sbjct: 702 T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
+ P F + DEG ++ + + P P+I W G+ + E +
Sbjct: 746 ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
E + C +L I +V + +G T NR G AS LK++ PP +PL+
Sbjct: 797 ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798
V++ +V+ V G P PT+T+ K +K + + I+I K
Sbjct: 852 DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+G KA+N G AE+ A +TVE+ EE+ P F+ ++ TVK V
Sbjct: 912 HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
NP P +TW+ N + + + N + +T +DS +G C A N+ G+
Sbjct: 972 NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029
Query: 919 AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
AR V + EK FV+ L ET + TV+ E + + WY +E+ D
Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
EI + D G I+ + + E S K T+
Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTV 1133
Score = 177 bits (430), Expect = 9e-44
Identities = 287/1251 (22%), Positives = 485/1251 (38%), Gaps = 155/1251 (12%)
Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
V+ L P G + + P+ +I W++ I PS Q D DN LVI +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 4552
Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
+DA + V + G + D +TV L
Sbjct: 4553 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 4586
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691
P K + Q V GS I LE P+ + W G+E+ ++ I+ D + Y
Sbjct: 4587 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4645
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750
VL+I + G Y V N G A+ + + EP ++PLK + +GE
Sbjct: 4646 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4698
Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ S + PR + W KN KP + DT ++K D Y +
Sbjct: 4699 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4757
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866
EN+ G AE+SA +TV++ + I + E V KG K+V V P + W
Sbjct: 4758 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4812
Query: 867 YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
R+ +IS + I + D L+I + D + D+G+Y N +GK+ A+ +D
Sbjct: 4813 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4870
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984
EK V+ L+ + E EG + + + S V KWY N +EI H E + G
Sbjct: 4871 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4929
Query: 985 XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
D G V+ D ++S L VVK + + + L+D +V+E L+V
Sbjct: 4930 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4989
Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095
++ + W ++G+ +KP + + FE++ + L I ++ D G Y +L D+
Sbjct: 4990 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 5049
Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143
+VV + ++ L++ +V +G+ T + + G+ V W KDG
Sbjct: 5050 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 5108
Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193
+Q + I ++ +DG L+I D G+Y N S C +T E+
Sbjct: 5109 VVLQKDDRITMRVALDGTAT-LRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQ 5167
Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244
PS F + L +P + + + V +P TL W+ I+ ++ TL
Sbjct: 5168 PSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ--WFLNGIPIKFDDRITLDDMADG 5225
Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
I DV++ KC E+ E C + + +PP+ +
Sbjct: 5226 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 5285
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354
RI G + + A P EW + K I+ HT + ++D + + I E +D
Sbjct: 5286 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 5344
Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
G+Y N G A+ + V IL+ + + + D+ N G
Sbjct: 5345 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 5401
Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458
+ V+ + W + ++TSIQ L N S +R A N
Sbjct: 5402 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 5461
Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
+ S + +E K + P K L ++ + + L C G P P++ WY
Sbjct: 5462 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 5521
Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
R+G+ L+ T + Y+C A N HG+ +T +Q
Sbjct: 5522 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 5581
Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+KP ++ +S+ + + + E VT G+P P V W K+G L
Sbjct: 5582 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 5637
Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
D + + + V +RIK Y A+N G+++ + +++ D
Sbjct: 5638 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5688
Score = 176 bits (429), Expect = 1e-43
Identities = 260/1229 (21%), Positives = 496/1229 (40%), Gaps = 133/1229 (10%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VAT 567
AP+F + L+ + ++ E +V G P + WF+ + + +M + + V T
Sbjct: 3188 APVFEQGLKKTSVKEKEEIKMEVKVGG-SAPDVEWFKDDKPVSEDGNHEMKKNPETGVFT 3246
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
LV+++ DAG +T A N AG T E EA ++
Sbjct: 3247 LVVKQAATTDAGKYTAKASNPAG----TAESSAEAEVTQS-------------------- 3282
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
LE PTF ++ V L + +P+P + WL G+ + D + +A
Sbjct: 3283 -LE--KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEG 3339
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
Y +K ++ G Y A N GEA + PP+ +E L + V+
Sbjct: 3340 SGSYSITIKDARLE--DSGKYACRATNPAGEAKTEANFAV-VKNLVPPEFVEKLSPLEVK 3396
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGV 802
+ ES LS +VVG P P++ W K++ P+ + ++ + S+TI ++ D G+
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQ-GDVGI 3455
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y+ +A N G A T+A + ++ PP F + + + V+E+ T+ L V PVP
Sbjct: 3456 YSCRARNEAGEALTTANFGIIR----DSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVP 3511
Query: 863 SITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
++ W+++++ I+ S ++ + L I E D G Y C A+N AG++ A
Sbjct: 3512 NVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGE-DVGVYTCKATNEAGEAKTTAN 3570
Query: 921 VTI--DVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ + ++E FV+ L K YE E+GK +++ + KW+ + I+ +D++ +I
Sbjct: 3571 MAVQEEIEAPLFVQGL-KPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIA-IDNQHVI 3628
Query: 977 Q---EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
+ E D G C ++ V + IP++ + Q E +V
Sbjct: 3629 EKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAE----EV 3684
Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
L +E ET V E D +++ K NK H + + +N + G++ +
Sbjct: 3685 KPLFIEPLKETFAV--EGDTVVLECKVNK-----ESHPQIKFFKNDQPVEIGQHMQLEVL 3737
Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
E ++T+ E + + + VN KA +L +IQF+ ++
Sbjct: 3738 EDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADL--------------KIQFAAKVE 3783
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
+ + +L ++ G++ VG++ + T + F + L V
Sbjct: 3784 EHVTDESGQL-------EEIGQFET-VGDTASSKTDT-GRGAPEF-VELLRSCTVTEKQQ 3833
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL 1271
A L ++ E + W K+ +E + + D TL T+ D EY C
Sbjct: 3834 AILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAE 3893
Query: 1272 DAKSTTKLKVEVV---EFPPKI----VDYEREYR---IKRGSDVTLLVDYQAFPQPNDEW 1321
+ + + ++ E PKI D+ + + + G L P+P+ +W
Sbjct: 3894 NEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKW 3953
Query: 1322 IVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADVEMNVTIL 1378
N + +K K ++D + LT+ + D Y+ N G +DV + V
Sbjct: 3954 YKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEP 4013
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQ 1437
+ +P + I E + +G + + + + + + ++ TQ
Sbjct: 4014 AQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQ 4073
Query: 1438 TS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTE 1494
I++ KT+ +R N+ ++++ + T + S T ++K L ++
Sbjct: 4074 RLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKGLTDVNVT 4125
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYK 1549
I L+ G P+ V WY+ + + +++ T E+ Y+
Sbjct: 4126 QGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYR 4184
Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIEGIPPPEV 1604
+ D VE+S V + K IS K Q G ++ IEG P +V
Sbjct: 4185 VVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEG-KPKDV 4242
Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYKNG+++++ K ++ + + I + + +Y++ A+N AG + + V
Sbjct: 4243 KWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSA 4300
Query: 1665 KPSKPEG--PVIMREISRESVTIEWKPPL 1691
KP G P +++ + ++ K P+
Sbjct: 4301 KPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Score = 171 bits (417), Expect = 4e-42
Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%)
Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563
MAP F+ K++ G + FEC V W + I+ ++ +
Sbjct: 2885 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2944
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
LV+ V PEDAG +TC+ +N AG + L V L +
Sbjct: 2945 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2993
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
P F + + ++LEC+++ P+P ++WL + I + S+
Sbjct: 2994 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 3040
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
+ES + + IT+ + +G YT +A N EG + L T + E P + L++
Sbjct: 3041 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 3095
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792
+ GE ++LS V G+P+P + + ++ K + TK +TH ++
Sbjct: 3096 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 3154
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+D Y A NS G A +++ IT + E P+F ++ +VKEK IK+
Sbjct: 3155 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 3208
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911
+V P + W+++++ +S + E + ++ + D+G Y ASN
Sbjct: 3209 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 3267
Query: 912 AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
AG +SS A VT +EK TFV+ L + E T+ + + S +W + + +
Sbjct: 3268 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 3327
Query: 969 GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020
I ++ D G C + + + VVK + PEF+
Sbjct: 3328 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 3387
Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077
KL EVKEK+ L V+ + + V W +D I N + +K+ + L I
Sbjct: 3388 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 3446
Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131
+ D G YSC R+E+ TA ++ +PPE +L+ +V + + T ++++T
Sbjct: 3447 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 3504
Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182
G + V WFKD I N HI +G L I +D G Y+C E G
Sbjct: 3505 VIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 3564
Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237
+K TA + V+E + F L + V A L V + + +V W+K I+
Sbjct: 3565 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 3623
Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286
+ + TL+I+ D +YTC + K T +LK+ F
Sbjct: 3624 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3683
Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344
P ++ +E G V L P ++ N + ++ +H + + + +
Sbjct: 3684 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3743
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
LTI+ + D G Y+ N G A+ ++ I
Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 169 bits (412), Expect = 1e-41
Identities = 255/1135 (22%), Positives = 433/1135 (38%), Gaps = 126/1135 (11%)
Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
TF K K Q + EG + P + W G+EI P+ + ++D Y V
Sbjct: 4684 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4741
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
+K N + TY +V N GEA L +K + ++++ L+ +V +G ++
Sbjct: 4742 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4799
Query: 755 SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P + W ++ + A + K D T+ + I+ +KD G YT++ N
Sbjct: 4800 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4857
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
G A++ A V+E E + + I + E V+ PV + WY+N+
Sbjct: 4858 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4909
Query: 871 EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
+ I P+ + G + EL I + D DYK V SN+AG A +T+ V
Sbjct: 4910 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4968
Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984
+ K + EE + V L+ + KWY N +E+ G E + G
Sbjct: 4969 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 5028
Query: 985 XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033
D G + ++ K + S +V K + P F+ L+D EV+E D+
Sbjct: 5029 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 5087
Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
L+ I E +V+WE+DG +++ L IR+ D G+Y +
Sbjct: 5088 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAK 5147
Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142
+E+ +A +VTV E P+ + L+ G+K F +++ ++WF +
Sbjct: 5148 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLN 5207
Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193
G I+F + I L DG L I D +D G C N T E +
Sbjct: 5208 GIPIKFDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 5266
Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244
LR P VP D + V P + T +V W+K IE T +
Sbjct: 5267 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 5325
Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290
+ V I I E D Y CV ++ A++ +VE++E + PKI
Sbjct: 5326 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 5385
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349
+ + G + L A P+ + W + ++ T + +A+L I
Sbjct: 5386 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 5445
Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
D G Y+ N G + +V + K + + W + G+
Sbjct: 5446 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 5502
Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455
S + V +W ++N +T +TS +L N S +R A
Sbjct: 5503 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 5562
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509
N + T + +T+ KP L +++ I+L C G+P
Sbjct: 5563 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 5622
Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561
P V W +DG L + ++ + N Y+C+A N++G T
Sbjct: 5623 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5682
Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
S VV Q P T+ D++ G + ++ P PE++WYK+G
Sbjct: 5683 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5740
Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I+ + + + + I Y + A+N +GT+ + T V P
Sbjct: 5741 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5795
Score = 156 bits (379), Expect = 1e-37
Identities = 258/1109 (23%), Positives = 438/1109 (39%), Gaps = 156/1109 (14%)
Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
F++ L+ + +G +F + PR + W++ IKP+ F + D LVI+
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4743
Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
+DA T+ V +N AG A S+ +L V+ I++G
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4785
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+ + Q V +G+ ++ E ++ PE D+ WL I N ++ + D Y
Sbjct: 4786 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4835
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
++ ++K G YTV +N G+A K E P+++ L+++ + +G+
Sbjct: 4836 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4889
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
+ +V P + W KN++ +K L K G + ++ D Y +
Sbjct: 4890 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4948
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N+ G ++SA +TV +P ++ +++ V+E ++L +V P I WY+
Sbjct: 4949 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 5002
Query: 869 NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926
N + + P ++ E+ E +T S+ D G Y+ V N G+ G+ V +
Sbjct: 5003 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 5062
Query: 927 K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975
K F+ L K E EEG + L+C + + W + + D +
Sbjct: 5063 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 5121
Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026
+G D+G + K++ S K T+ P+F+ L+
Sbjct: 5122 ALDG-TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 5180
Query: 1027 EVKEKDVAILEVEINSETADVV-WERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
D V++ + W +G IK + D G+ L IR+ D
Sbjct: 5181 AALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYC-LTIRDVREEDF 5239
Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128
G CI ++E+ T E TV E PP L ++++ G+ E
Sbjct: 5240 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 5298
Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
+ A V WFKDG +I+ + H ++ T+DG ++KI + D G Y C E+G
Sbjct: 5299 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 5357
Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
++ A VE P IN L E V L+ ++ V
Sbjct: 5358 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 5414
Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
WYK + D+ + TL I TE+D Y CV +A T V V+
Sbjct: 5415 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 5474
Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334
P + V E E RG TL P P +W N ++++ T
Sbjct: 5475 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 5534
Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386
+ S D S SLT+ + +D GIY+ EN G A V+M + +KP GK
Sbjct: 5535 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437
P ILE+ S+ N+ E + TG N ++ + I+ + EW + + Q
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490
I+N + +R A NE + S TT+ + + + T Q P + +
Sbjct: 5654 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5709
Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+ T + ++L C P P++ WY+DG
Sbjct: 5710 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5738
Score = 149 bits (361), Expect = 2e-35
Identities = 173/749 (23%), Positives = 292/749 (38%), Gaps = 93/749 (12%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S E + F+ L+ +G + +C + G P P++ W + +++ M
Sbjct: 5064 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 5123
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
D ATL IR D G + AKN AG A+S ++ V ++ G + +
Sbjct: 5124 DGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTV----TEQGEQPS---------- 5169
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
P F K G ++ +P+P + W G I D+ I++
Sbjct: 5170 ----------KPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITL 5219
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734
+D + YC L I +V++ GT +A N G + G + P
Sbjct: 5220 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
P+ PL + G+ + + V NP + W K+ K ++ T+ +K
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 794 --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846
P + D GVY A N G AET A VE E EE P ++ TV
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
I+L +V P S+ WY++ + + ++ + + N +E D G Y+C
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 5456
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956
VA+N+ G + V + V K K ++ + T + G + L+C +
Sbjct: 5457 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 5516
Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007
KWY N + + R +I+ D G+ +C K Q T+
Sbjct: 5517 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 5575
Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055
+ + +T P+FI +L D V +V LE ++ V W +DG +
Sbjct: 5576 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 5635
Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101
I+ + ++ E + +L I+N +VHDEG Y C+ +E+ +A V
Sbjct: 5636 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5695
Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158
PP ++ + + +G E ++ + W+KDG+ + S+ IQ+++ DG
Sbjct: 5696 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5755
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
L I C DD G Y N TA
Sbjct: 5756 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5783
Score = 143 bits (346), Expect = 1e-33
Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+ + AP L K G ++ C+V+ PR + W++ ++ + Y++D
Sbjct: 5377 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 5436
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
ATL I + ED G + CVA NA G +++ + V+ P + E
Sbjct: 5437 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 5483
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
G P F+K + D G L+C + P P+I W G+ +
Sbjct: 5484 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 5534
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733
IE+ CS L + EG Y A N G+A +L K K E +
Sbjct: 5535 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
PP+ I L M V G + L +V G P P++ W K+ P+ ++
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845
+ +K V DEG Y A N G A T + + +++ ++PP F + ++
Sbjct: 5654 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5713
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
E +KL +V +P+P + WY++ I++PS+ I + + + ++ D G Y+
Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5773
Query: 906 CVASNSAGKSSHGARVTI 923
+A+N +G + T+
Sbjct: 5774 VIATNPSGTAQDKGTATV 5791
Score = 141 bits (342), Expect = 4e-33
Identities = 270/1279 (21%), Positives = 483/1279 (37%), Gaps = 84/1279 (6%)
Query: 151 VTLEKSDLFDSQEDESKPD-VSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKI 209
+T E + S + E P+ V + P++ ++ KS K I E + K + +V EK
Sbjct: 1515 MTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKP 1574
Query: 210 NVPDDKETS-QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXX--X 266
P KE S + P S K+S+ +K K+ + E + P+
Sbjct: 1575 ASPTKKEKSPEKPASPTKKSE-NEVKSPTKKEKSPEKSVVEELKSPKEKSPEKADDKPKS 1633
Query: 267 XXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQ 326
E S K +KS K S KP +K K +K
Sbjct: 1634 PTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDDEVKSPTKKEKS 1693
Query: 327 VFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRK 386
+ P + + P S + V+S K+++ E++ KE PE+ K
Sbjct: 1694 PQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVK 1753
Query: 387 SSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLY 446
S +K ++ ++ +K +P + +PV++ D V + T + + + E
Sbjct: 1754 SPTKK-EKSPEKSAEEKPKSPTKKESSPVKM-ADDEV------KSPTKKEKSPEKVEEKP 1805
Query: 447 ILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQ 506
T + +K EE P + ++ T+ + EK + P EKP S
Sbjct: 1806 ASPTKKEKT--PEKSAAEELK-SPTKKEKSPSSPTKKTGDESKEKSPEKPE-EKPKSPTP 1861
Query: 507 SMAPIFVEKLRPKHTPDGST-----VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
+P K + +P+ + + +++ + + F +++ + + + + D
Sbjct: 1862 KKSPPGSPKKKKSKSPEAEKPPAPKLTRDLKLQTVNKTDLAHFE--VVVEHATECKWFLD 1919
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
+ T V +D F C + + F S T ++ + GS T
Sbjct: 1920 GKEITTAQGVTVSKDDQFEFRC-SIDTTMFGSGTVSVVAS---NAAGSVETKTELKVLET 1975
Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
E P F+ K + V +G + ++ ++A+ P W G ++ D
Sbjct: 1976 PK------ETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGN-LLEDGKNG 2026
Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
V I+++ + S L I N + G TV A N G + L + P V++
Sbjct: 2027 VTIKNEENK--SSLIIPNAQ--DSGKITVEASNEVGSSESSAQLTVNP-PSTTPIVVDGP 2081
Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
KS+ +++ E+ A + G P PT+ W N K V+ T + T + LK K E
Sbjct: 2082 KSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQ 2141
Query: 802 VYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-R 858
T+K A+NS G A + V E N + P F ++ + E ++ +
Sbjct: 2142 TGTVKVTAQNSAGQDSKQADLKV----EPNVKAPKFKSQLTDKVADEGEPLRWNLELDGP 2197
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
+P ++W N + ++ S+T+ G+ + I E+ SG A N+AG+
Sbjct: 2198 SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEM-SGTLTAKAKNAAGECET 2256
Query: 918 GARVTID--VEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHRE 974
A+VT++ +K FV+ Q T E T + + WY N K++ + +
Sbjct: 2257 SAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVK 2316
Query: 975 I--IQEGRXXXXXXXXXXXXDVGVIKCIV-----KDQETSTMLVVKET-IPEFIRKLQDF 1026
+ + E G I+ K Q T+ + V K+T +P+F + D
Sbjct: 2317 VKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDDR 2376
Query: 1027 EVKE-KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
+VKE +DV V W +GE + N +K G + I + G
Sbjct: 2377 QVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGE-HTIEISAVTPEQAG 2435
Query: 1086 EYSCIL------RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE--IELTKGDALV 1137
E SC + V V P L+++ + +G + + + K +
Sbjct: 2436 ELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKI 2495
Query: 1138 RWFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYS----CEVGNSKCTAILTVE 1192
W KDG EI H ++ + KL I L+D G + E G ++C+A L V
Sbjct: 2496 TWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVV 2555
Query: 1193 E--PSIN--FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDV 1248
+ P F + L +T + D T V WY ++ TE + +
Sbjct: 2556 KGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNAN 2615
Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDV 1305
T+ I T D + CV + + + P V++E + + G +
Sbjct: 2616 GVYTMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTL 2675
Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
L P+P W VN K +++ ++ K + + ++TIK + +G N
Sbjct: 2676 KLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINE 2735
Query: 1366 CGHADVEMNVTILDKPSPP 1384
G A E + +L + PP
Sbjct: 2736 YGKATSEATLLVLPRGEPP 2754
Score = 139 bits (337), Expect = 2e-32
Identities = 180/762 (23%), Positives = 288/762 (37%), Gaps = 105/762 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F L + P G + EC V+ P ++ WF+ I+ + ++ D +
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I D G + CVA N G A T+ + + +H E +
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAE--TQATYQVEILEHVEE------------EKRREYA 5382
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
I P K V+ G I L C++ AIP + W G + D S+ E D
Sbjct: 5383 PKINPPLEDKT----VNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG- 5437
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQVIEPLKS 743
+ L I + + G Y VA N G + + +K E E P + L
Sbjct: 5438 --TATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVD 5495
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKALPTKSDGDTHSITILKPKKVK 798
+ +G+S L V G+P P I W +N N P + T DG S+T+ +
Sbjct: 5496 LWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC-SLTV-NESTMS 5553
Query: 799 DEGVYTLKAENSEGIAETSAVITV-------EEPTEENAEPPLFINRFQEITVKEKGTIK 851
DEG+Y +AEN+ G A+T A V E+P + +PP FI +++V I
Sbjct: 5554 DEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVID 5613
Query: 852 LVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVAS 909
L +VT P PS+ W ++ +I S N + + +L I N D G Y+CVA+
Sbjct: 5614 LECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVH-DEGTYRCVAT 5672
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQT--SHTVST 958
N G ++ + V +D + V + T EG+ + LEC+ S
Sbjct: 5673 NENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEM 5732
Query: 959 KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVV 1012
WY + ++ D +I + D G+ + I + Q+ T V
Sbjct: 5733 VWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVK 5792
Query: 1013 K------------------ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
K P+ + L++ + EK L + + + + W +DG
Sbjct: 5793 KLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDG 5852
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVTVVELPP 1107
E + P E + +L + + + D G Y C+ + SC V + P
Sbjct: 5853 ERVFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKP 5912
Query: 1108 EII-------------TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152
I T L ++ G+ TFE L G+ ++W KDG E+ I
Sbjct: 5913 RDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFEC-LPFGNPFPSIKWLKDGLELFSDEKI 5971
Query: 1153 QL--TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
++ DG Q+L + D G + C N TA E
Sbjct: 5972 KMEAAADG-TQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Score = 133 bits (321), Expect = 2e-30
Identities = 185/819 (22%), Positives = 326/819 (39%), Gaps = 81/819 (9%)
Query: 936 KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989
K + ++G + + EC T V KW + KEI + + EG
Sbjct: 2894 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2953
Query: 990 XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036
D G CIV KD +T+ V++ + PEFI LQD K + +L
Sbjct: 2954 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 3013
Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
E ++ E V W D + I + E + ++ I ++ + +G+Y+CI +
Sbjct: 3014 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 3071
Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143
T++ +TV P LQN++++ G K + KG + K
Sbjct: 3072 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 3130
Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195
++I S+ I + D ++ I +D Y NS TA T VE P
Sbjct: 3131 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 3190
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253
L+ V + + V++ DV W+K K V ED + + TL
Sbjct: 3191 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 3247
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309
++++ D +YT + T + + EV + P V +K TL V
Sbjct: 3248 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 3307
Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P+ EW+ + + ++ H ++ S S S+TIK D+G Y R N G
Sbjct: 3308 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 3367
Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
A E N ++ PP K + LE+ + T + VE+ + DT
Sbjct: 3368 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 3422
Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
I ++ + QT++ +L N + + Y+ + + + TT + +I+++
Sbjct: 3423 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 3480
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534
P + L+ + E ++L G P P V W++D K + AK
Sbjct: 3481 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT 3540
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593
Y C A N+ GE +T+ + +Q++ + + +K + + G +
Sbjct: 3541 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 3600
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651
+EG P PEV W+K+G + D ++ I K + + + IK+ + KYT +A+N A
Sbjct: 3601 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3660
Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686
G LK+ ++K + E + E +E+ +E
Sbjct: 3661 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3699
Score = 131 bits (316), Expect = 6e-30
Identities = 145/606 (23%), Positives = 250/606 (41%), Gaps = 53/606 (8%)
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P PDI W ++ DE + + D + I V+ G YT +A N
Sbjct: 570 KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626
Query: 716 EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
G+AS ++ EKE PP + L+ ++G+ + +V G P P + W +++
Sbjct: 627 YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686
Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
P++ + DG T + I + + D GVYT+K +N G E+ A + V+ ++N
Sbjct: 687 PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
P F + + E ++ + +T +P P I W+ N + +S SE + + L
Sbjct: 746 VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948
I +V D G C SN G +S R+ + V TF K L+ +E TV+
Sbjct: 806 TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863
Query: 949 ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
E S T K+ +G + EI+ +G G I +++
Sbjct: 864 EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923
Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
E+ L V++ + P F++ ++D VK + A+ E + + +V W +G
Sbjct: 924 HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104
+ E H KL I S G C + R E+ V + +
Sbjct: 984 HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+
Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101
Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + ++DAGE NS + A LTV++ PEF L P + LTVE
Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPF-----APEFDLRPVS----LTVE 1152
Query: 1220 IPDETL 1225
E +
Sbjct: 1153 KGSEAV 1158
Score = 130 bits (313), Expect = 1e-29
Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K +++ P F + L G + +C V G P P+I W+R +++ +
Sbjct: 5477 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 5536
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
D +L + E D G + C A+NA G A + V+ L
Sbjct: 5537 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 5582
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ EG PP F + V G+ I LEC++ +P P + W G ++ D
Sbjct: 5583 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5640
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732
+ E+ +Y L+I N EGTY VA N G A+ +++ G
Sbjct: 5641 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5698
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789
+PP+ + + +G+ + L +V +P P + W K+ A+ T SD S+
Sbjct: 5699 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5754
Query: 790 ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832
T+L P V D+G+Y + A N G A+ TV++ P + A +
Sbjct: 5755 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5814
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890
P + + I + EK + +L + + +P P+I W+++ E + P + ++ DG EL
Sbjct: 5815 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5873
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
V+ + + D+G Y+CVA N+ G + V +
Sbjct: 5874 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5905
Score = 127 bits (306), Expect = 1e-28
Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+ + AP +E L P+ + + C+ G P+P I WF+ + P Q+ D
Sbjct: 5810 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5869
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
V LV+ +DAG + CVA+N G S+ T V D
Sbjct: 5870 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5915
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
+ I EG P F+ + G + EC P P I WL G E+ DE I +
Sbjct: 5916 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5975
Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731
+D L +++V EG + VA N G AS L I+ GE
Sbjct: 5976 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 732 KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782
E P++ L +M + +G V + G P PT+ W K+ + + K +
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834
+ H + I+ DEG Y+L+A N G A+T + + P +A+ PP
Sbjct: 6093 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 6151
Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893
F+ + + V V +P P + W+ N + I P I Q+ G + L+I
Sbjct: 6152 FVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 6211
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ E D+G+Y A NS G +S A + + V + +K
Sbjct: 6212 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 6249
Score = 121 bits (292), Expect = 5e-27
Identities = 224/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
+P+ L D YT E I++ + E P V L P+G
Sbjct: 4839 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4891
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
F+ +V P Q+ W++ IKP+ + L I +D + V NA
Sbjct: 4892 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4950
Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
AG S+ L V P I++G+ ++P+
Sbjct: 4951 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4983
Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
+ L+ ++ IP+ I W G+E+ PD + E L I + KK G Y
Sbjct: 4984 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 5040
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764
VV N +GE V+ +K+ + P + PLK V +G+ + L + G P P
Sbjct: 5041 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 5100
Query: 765 TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
+ W K+ ++ + DG T ++ I KK D G Y + A+N G A +
Sbjct: 5101 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSAKK-SDIGQYRVTAKNEAGSATSDCK 5158
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+TV E E+ ++P F+ + + +V P P++ W+ N I + I
Sbjct: 5159 VTVTEQGEQPSKPK-FVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRI 5217
Query: 880 T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928
T + N L I +V E D G KC+A N G + H D+
Sbjct: 5218 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985
G + +EC + T +W+ + K+I H EI
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030
D+GV C+ ++ ET V +E P+ L+D V
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
L ++++ A VVW +DG ++ + +E+ G L I +++ D G Y
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 5455
Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
C+ + SC+ V V + P L + ++G+ T + +T GD
Sbjct: 5456 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 5514
Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
++W+++G ++ I+ + DG L + + + D G Y CE G +K A
Sbjct: 5515 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 5573
Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233
V E+P ++ + P+FIL ++ L I E V W K
Sbjct: 5574 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 5632
Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283
+ + +F ++ K L I+ T D+ Y CV + +TTK V +
Sbjct: 5633 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5692
Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
PP+ + R G + L A P P W + I+ + S+
Sbjct: 5693 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5752
Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
A+L I D GIY++ N G A + T+ P G
Sbjct: 5753 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5799
Score = 116 bits (278), Expect = 2e-25
Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
EKP +E P F+ +L G+ + EC+V G P P + W + + F+
Sbjct: 5585 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5643
Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ V L I+ D GT+ CVA N G S+TT+ V D G V
Sbjct: 5644 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5698
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
PP F+ K EG + LEC++ A P P++ W G + P
Sbjct: 5699 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5744
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
+ I +++ D + L I + +G Y V+A N G A +K +G +
Sbjct: 5745 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5801
Query: 733 -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778
+ P+++EPL+++ + + +S L + G+P+PTI W K+ + P L
Sbjct: 5802 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5861
Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829
D ++ +D G Y AEN+ G A TS + V +P +
Sbjct: 5862 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5921
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+ P F K ++ NP PSI W ++ + E I + +
Sbjct: 5922 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5981
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944
+I + + + G ++CVA+N G +S A + I+ ++ + L + + E EE K
Sbjct: 5982 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 6037
Score = 114 bits (274), Expect = 7e-25
Identities = 135/593 (22%), Positives = 242/593 (40%), Gaps = 45/593 (7%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
P++ L+ Q VNK + A FE+ + +WF DG EI + + ++ D + + +
Sbjct: 1885 PKLTRDLKLQTVNKTDLAHFEVVVEHATEC-KWFLDGKEITTAQGVTVSKDDQFE----F 1939
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ET- 1224
C +D S V A +VE + L P+ P TD +E+ +T
Sbjct: 1940 RCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTV 1999
Query: 1225 -LDVT--------WYKKKSVIEDTEK-FTLISDVKKRTLIIRKCTEDDQC--EYTCVLLD 1272
+DV WY+ +++ED + T+ ++ K +LII + + E + +
Sbjct: 2000 QMDVIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGS 2059
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
++S+ +L V P +VD + IK FP P +W +N KI+++ +
Sbjct: 2060 SESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESR 2119
Query: 1333 H--TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
T + D + ++ K+E T G K+ +N+ G + ++ + P + L
Sbjct: 2120 TITTIKTEDVYTLKISNAKIEQT--GTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQL 2177
Query: 1391 --EIDSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKT 1445
++ + W+ E + T + +++ Q + ++ + V + +I K
Sbjct: 2178 TDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKP 2237
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
S A A N A E KV + P + +N T E ++ + I
Sbjct: 2238 EMSGTLTAKAKNA-----AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIV 2292
Query: 1506 GGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCI---AFNDHGEV 1559
G P P VTWY + KKL + K Y + I A N G+V
Sbjct: 2293 TGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKV 2352
Query: 1560 ETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
+ + + + +K + +N D +Q K G++ TA +EG P P V W NG +
Sbjct: 2353 QATAQLKVDKKTEVPKFTTNMDDRQV-KEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHP 2411
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL---KVYDKPS 1667
+T K+ I I + + + + EA+N G+ +V L KV D P+
Sbjct: 2412 NITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPT 2464
Score = 112 bits (269), Expect = 3e-24
Identities = 206/1012 (20%), Positives = 379/1012 (37%), Gaps = 71/1012 (7%)
Query: 726 KIKTGEKEP-PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKS 782
K EK P P++ LK V + + + +VV W + K + T S
Sbjct: 1875 KSPEAEKPPAPKLTRDLKLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVS 1932
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
D + G ++ A N+ G ET + V E +E +P F ++ +++
Sbjct: 1933 KDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPE-FTDKLRDM 1991
Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDS 901
V + T+++ +P+ WY+N ++ + +T + L+I N DS
Sbjct: 1992 EVTKGDTVQMDVIALHSPL--YKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DS 2046
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILECQTSH--TVST 958
G ASN G S A++T++ T V KS +E +T + S +
Sbjct: 2047 GKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTV 2106
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKE 1014
KW N+K + I+ G +K ++ Q++ L V+
Sbjct: 2107 KWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEP 2166
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEIIKPKKNKYDFEKRGH 1070
+ P+F +L D E + +E++ S +V W +G+ + +
Sbjct: 2167 NVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDG 2226
Query: 1071 IRKLYIRNTSVHDEGEYSCILRDES--C--TAEVTVV--ELPPEIITRLQNQKVNKGNKA 1124
+ I G + ++ + C +A+VTV PE + QN +
Sbjct: 2227 TYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESV 2286
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV- 1180
F +T K V W+ + ++ S +++ + K ++I ++ G E
Sbjct: 2287 KFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAE 2346
Query: 1181 ---GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
G + TA L V++ + FT + + V D T + V W
Sbjct: 2347 NVSGKVQATAQLKVDKKTEVPKFTTNMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGE 2405
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
+ T+ + T+ I T + CE T + K +L V+ V P
Sbjct: 2406 PVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTF 2465
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTI 1347
+ I G ++TL+ P+P W+ + I H K + S L+I
Sbjct: 2466 AKNLEDRLITEG-ELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSI 2524
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN- 1406
+ + D G ++ E+ G A+ ++ ++ K P KP + D + IN+ +
Sbjct: 2525 LQTKLEDKGRITIKAESEFGVAECSASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLEC 2582
Query: 1407 ----TGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460
TG+ T + + + Q + TE + N T I + + + + + A N+
Sbjct: 2583 KLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA- 2641
Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
+ S T KV+ ++ E L + T + ++L + G P+P V+WY +GK
Sbjct: 2642 -GEVS-TEGPLKVVAPIPVE---FETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGK 2696
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYK----CIAFNDHGEVETSCVVGIQQKPVITIS 1576
KL+ ++ + Y C A N++G+ + + + +
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 1577 NEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
E + + + G + + V G P P + WY N ++ N Y I T +KTS + I
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 1636 KRS-HSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVT 1684
H + +A N AG S + Y D S+ E E + +T
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLT 2868
Score = 111 bits (268), Expect = 4e-24
Identities = 145/628 (23%), Positives = 251/628 (39%), Gaps = 53/628 (8%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
Q S + +V G P P ITW K++ + + SD D + P +V D G YT
Sbjct: 561 QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N G A TSA V + E+ A PP F+ + ++ KE I V P P +
Sbjct: 621 CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
W +++ + PS +DG+ +L I + + D+G Y N G A + +
Sbjct: 680 VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738
Query: 924 -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
D +K Q + E +EG+ V + + + + W+ N K +S + + I
Sbjct: 739 ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798
Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031
E G++ C ++ S + V P F + L+D V+EK
Sbjct: 799 EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858
Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088
+ EV+++ + + G+ +K + + ++ I NTS+ HD GE
Sbjct: 859 STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917
Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137
++E TAE +TV + P + +++Q V G A FE + + V
Sbjct: 918 AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977
Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
WF +G ++ Q S +++ KL I AG C VG + A L V
Sbjct: 978 TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035
Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
P + P+F+ + + D + E+ E VTWY K ++ +++ +
Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301
+ I+ +D E V +++ + KL V+ F P+ +++
Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
GS+ P P EW VN + ++
Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVR 1181
Score = 108 bits (260), Expect = 4e-23
Identities = 120/526 (22%), Positives = 205/526 (38%), Gaps = 39/526 (7%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E PP F K + + EG I EC + PEP++ WL + + P + + +
Sbjct: 644 EAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ-- 701
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIV 746
+ L+I + + G YTV N G L ++ + P+ ++ +
Sbjct: 702 --TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVEC 759
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGVYT 804
+GE V + + G+P P I W N KP+ I IL K V +G+ T
Sbjct: 760 DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVT 819
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
+ N G A + V P PP F ++ TV+EK T+ V+ P P++
Sbjct: 820 CQGSNRLGSASCDGRLKVRVP----PAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTL 875
Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
T+ + + E + + + I N + G+ A N G + AR+T+
Sbjct: 876 TFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV 935
Query: 924 DVEK------VTFVKHLQ-KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ E+ TF+K ++ ++ +T E + + W+ N ++ +
Sbjct: 936 EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMD-QGSPGVK 994
Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----KETIPEFIRKLQDFE 1027
E G + C ++ ET LVV ++ P+F+ L D
Sbjct: 995 IEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKT 1054
Query: 1028 VKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
+ + EV + E V W GE +K E G I K+ I+N + D GE
Sbjct: 1055 ETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSI-KISIKNIKIEDAGE 1113
Query: 1087 YSCILRD----ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATF 1126
+ + + A++TV + P PE R + V KG++A F
Sbjct: 1114 IRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVF 1159
Score = 102 bits (244), Expect = 3e-21
Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%)
Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144
+ DES E+ P P+ IT++++ K KG+ A FE + TKG +W KDG
Sbjct: 2867 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2925
Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194
EI+ I++ T G + Q+L + + +DAG+Y+C V G C A LTV E
Sbjct: 2926 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2985
Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246
+ PEFI+ T + +E I + V+W + K++ +++ +
Sbjct: 2986 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 3045
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304
V++ T+ + + Q +YTC+ + + T+K + + V P + + G
Sbjct: 3046 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 3103
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356
+ L + PQP+ ++ S+ K + K T S I+ + + I ++ D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
YK N+ G A +T + +P + + + E + G++ + +
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
+ + + +K +T ++ T + ++ A A N +++S E +
Sbjct: 3223 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 3281
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527
++ PT + L + NE L+ GVP P V W +DG+ ++T AK
Sbjct: 3282 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 3337
Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586
Y C A N GE +T + + V E + + K
Sbjct: 3338 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 3397
Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644
+ ++ + G P P V W+K+ + D + I T + + I + ++ Y+
Sbjct: 3398 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 3457
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688
A N AG + + PE +R + RE T++ K
Sbjct: 3458 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 3502
Score = 97.1 bits (231), Expect = 1e-19
Identities = 113/461 (24%), Positives = 185/461 (40%), Gaps = 44/461 (9%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F + L K + STV FE V G+P P +T+ +K ++ D +
Sbjct: 844 PTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRIS 903
Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + G A+N G A S L VE + S
Sbjct: 904 IPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA------------------ 945
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
PTF K + Q V G + E + P P++ W G ++ D+ S ++ +
Sbjct: 946 -----PTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM--DQG-SPGVKIEA 997
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
H + L I + + GT A N G E +V+ +K+PP+ +E L
Sbjct: 998 HNHDHKLTIDSAQ--YAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTE 1055
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITI-LKPKKVKDEGVYT 804
+V+ +V G P+PT+TW + +K + SI I +K K++D G
Sbjct: 1056 TVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A NSEG ET A +TV++ P F R +TV++ A P+P+
Sbjct: 1116 AVATNSEGSDETKAKLTVQK----KPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTY 1171
Query: 865 TWYRNNEIISPSET---ITQN---FDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917
W N + + +T++ DG +I + T SE++ VA N+ G
Sbjct: 1172 EWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEET 1231
Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
GA++TI+ +K + V Q +E K + + + + +T
Sbjct: 1232 GAQLTIEPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 96.7 bits (230), Expect = 2e-19
Identities = 146/708 (20%), Positives = 276/708 (38%), Gaps = 67/708 (9%)
Query: 1046 DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100
D+ W +D ++ + +++ + ++ G + I V D G Y+C+ +E S +A
Sbjct: 578 DITWYKDDVQLHEDERHTFYSDEDGFFA-MTIDPVQVTDTGRYTCMATNEYGQASTSAFF 636
Query: 1101 TVVEL-----PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL 1154
V+++ PP +T+L++++ +G+ FE E+ + + W D ++ S+ +L
Sbjct: 637 RVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRL 696
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE-EPSINFTLRLPEFILVP 1209
DG+ KL+I D DD G Y+ ++ G+ + A L V+ +P N PEF
Sbjct: 697 QYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVA--PEFQATI 754
Query: 1210 ANTDA-------YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+ + +V D ++ W+ + ++EK IS+ L I+ T
Sbjct: 755 EYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHF 814
Query: 1263 QCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
TC L A +LKV V PP + ++ S V VD +P+P
Sbjct: 815 DGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPT 874
Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
+ + K +K + + S+ ++ D I + +N G A+ +
Sbjct: 875 LTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVA-KAQNEHGTAESRARL 933
Query: 1376 TI-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNI 1433
T+ ++ P L+ I D+ TG + V W I+ +
Sbjct: 934 TVEQEEEESRSAPTFLK----DIE---DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM 986
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEK-PLK- 1489
+ ++ N ++ + + A ++ + +P +K P K
Sbjct: 987 DQGSPGVKIEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKF 1046
Query: 1490 -NITTEPNEDIELTCIFG----GVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX 1540
I + E ++ T +F G P+P VTWY G++LK + ++
Sbjct: 1047 VEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNI 1106
Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGI 1599
+ +A N G ET + +Q+KP + + G E + +A GI
Sbjct: 1107 KIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGI 1166
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--------TIEASNTA 1651
P P W NG K+ + +E T+++++V L ++ Y ++ A NT
Sbjct: 1167 PLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTL 1226
Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
G L + +P K V +++S V E + + E T
Sbjct: 1227 GAEETGAQLTI--EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 90.6 bits (215), Expect = 1e-17
Identities = 86/357 (24%), Positives = 146/357 (40%), Gaps = 16/357 (4%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G PTF+K + + + EG L++ +L + P+P I WL G EI D + + E D
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQ 748
+ S+L+ K +G T+ A + G A L + G P + + + +
Sbjct: 2520 LKLSILQ---TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTE 2576
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-- 806
G+++ + G+P P + W + V A + + + +K V + +K
Sbjct: 2577 GDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCV 2636
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G T + V P P F + T +E T+KL A + P P ++W
Sbjct: 2637 AYNKAGEVSTEGPLKVVAPI-----PVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSW 2691
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--D 924
Y N + + S+ I + + + I ++ + SG C A N GK++ A + +
Sbjct: 2692 YVNGKKLEESQNIKIHSEKGTYTVTIKDITCDY-SGQVVCEAINEYGKATSEATLLVLPR 2750
Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGR 980
E F++ L K V T S WY N KEI D I+ + +
Sbjct: 2751 GEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDK 2807
Score = 88.6 bits (210), Expect = 4e-17
Identities = 75/271 (27%), Positives = 124/271 (45%), Gaps = 20/271 (7%)
Query: 653 LECRLVAI--PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
LEC+L+ P P + W + + E+ ++ + ++ +KI V G
Sbjct: 2580 LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVY----TMKIHGVTADMTGKIKC 2635
Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
VA N+ GE S LK+ P + L R+G+++ L A ++G P P ++W
Sbjct: 2636 VAYNKAGEVSTEGPLKVVA--PIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693
Query: 771 NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
N K ++ + S+ T+++TI K G +A N G A + A + V
Sbjct: 2694 NGKKLEESQNIKIHSEKGTYTVTI-KDITCDYSGQVVCEAINEYGKATSEATLLVLP--- 2749
Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDG 885
EPP F+ + + GT K+V +V T +P PS+TWY NN+ I S+ T D
Sbjct: 2750 -RGEPPDFLEWLSNVRART-GT-KVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDD 2806
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
+ L I + + ++ G+ C A N AG+ S
Sbjct: 2807 KTSTLTINSFNPDVHVGEIICKAENDAGEVS 2837
Score = 86.2 bits (204), Expect = 2e-16
Identities = 151/715 (21%), Positives = 276/715 (38%), Gaps = 68/715 (9%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P F+ KL+D E KE DV E E+ ++VW D + ++P + + + G KL
Sbjct: 648 PAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHD-FRLQYDGQTAKLE 706
Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PEIITRLQNQKVNKGNKAT 1125
IR+ D G Y+ +++E AE+ V P PE ++ + ++G +
Sbjct: 707 IRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVR 766
Query: 1126 FEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179
F+ +T GD + WF +G + S ++ + L I D G +C+
Sbjct: 767 FKSVIT-GDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNR 825
Query: 1180 VGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI---PDETLDVTWYKKKSV 1235
+G++ C L V P T P E V + V++ P+ TL T K+
Sbjct: 826 LGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELK 885
Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE-----F 1286
+ + D R I + E + A+S +L VE E
Sbjct: 886 NGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA 945
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASL 1345
P + D E + +K G + P P W +N K+ + K + L
Sbjct: 946 PTFLKDIE-DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHDHKL 1004
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-----DSSSINIC 1400
TI + AG R EN G + + + +L P +EI ++ +
Sbjct: 1005 TIDSAQY--AGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVV 1062
Query: 1401 WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458
++ E T+ +Y+ + +E+ ++ + ++ + + SI+N+K + RA A N
Sbjct: 1063 FEVRVEGEPKPTVTWYL-KGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATN- 1120
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
S+ S+ T+ K+ + K +P + ++T E + + G+P P W +
Sbjct: 1121 ---SEGSDETKA-KLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVN 1176
Query: 1519 GKKLKT----AKATYENRXXXXXXXXXXXXXXXY--------KCIAFNDHGEVETSCVVG 1566
G+K++ A+ T + Y +A N G ET +
Sbjct: 1177 GRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLT 1236
Query: 1567 IQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I+ +K + + +D+ +V E + ++ P L + K ++T E
Sbjct: 1237 IEPKKESVVVEKQDLSSS-EVQKE--IAQQVKEASPEATTTITMETSLTSTKTTTMSTTE 1293
Query: 1626 KTSVIR--IKELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
TS + E K S S S T+ + G + +++ + SK + +RE
Sbjct: 1294 VTSTVGGVTVETKESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVRE 1348
Score = 70.9 bits (166), Expect = 9e-12
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
+Y E + + + P+PDI W F+G +I S + L IT K
Sbjct: 6419 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 6478
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y A N G+A I++ + T P I+PL + + + + +V G P
Sbjct: 6479 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
P + W K +P+ + DG I+ +D G+Y+ A N G A TS
Sbjct: 6535 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 6594
Query: 820 ITVEEPTEEN 829
+TVE + N
Sbjct: 6595 VTVEAEGDYN 6604
Score = 60.5 bits (140), Expect = 1e-08
Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531
K+++ ++P L++ TT+ +E + L C G P+PKV+W D K + T E+
Sbjct: 2987 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 3046
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589
Y CIA N G +T + +Q + PV T ++++ K +G++
Sbjct: 3047 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 3103
Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641
+++ ++G P P V +Y K K+ + I + + R I ++ +
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y A+N+ G TS+ ++T KV + P +G +E + +E K +E
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
K E N+ K + + V T +++ + A NP G +E+
Sbjct: 3223 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 3273
Score = 57.6 bits (133), Expect = 9e-08
Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 3/149 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+Q P FVE L K +TV FE +VEG P+P +TW+ + +K S ++ D
Sbjct: 1038 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 1097
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXX 622
++ + I+ + EDAG VA N+ G + +L V+ P + V
Sbjct: 1098 SI-KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSE 1156
Query: 623 XXXADILEGIP-PTFSKKPKAQYVDEGSD 650
+ GIP PT+ + V +G +
Sbjct: 1157 AVFSAHAFGIPLPTYEWSVNGRKVRDGQE 1185
Score = 57.6 bits (133), Expect = 9e-08
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565
S+ P F +KLRP + T+ + V G P P + WF+ I D+
Sbjct: 3479 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGH 3538
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608
TL I++ ED G +TC A N AG A +T + V EAPL G
Sbjct: 3539 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 3585
Score = 57.2 bits (132), Expect = 1e-07
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 9/171 (5%)
Query: 1507 GVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P +TWY+D +L T + + Y C+A N++G+ T
Sbjct: 573 GYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQAST 632
Query: 1562 SC---VVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
S V+ ++++ ++ K K GD +EG P PE++W + L
Sbjct: 633 SAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSH 692
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
++ + +T+ + I++ + + YT++ N G+ + L V P K
Sbjct: 693 DFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDK 743
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
++P + +PL+NI + L C F G P+P + W++DG+++ + +
Sbjct: 5813 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5872
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581
Y+C+A N +G TSC V + +KP I S + K
Sbjct: 5873 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5932
Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639
++ K GD + G P P + W K+G +L +D++ + + T + + ++
Sbjct: 5933 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5992
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ A+N GT+S + L +
Sbjct: 5993 EGYFRCVATNEHGTASTKAELVI 6015
Score = 55.6 bits (128), Expect = 4e-07
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
D YT +Q + K +F + ++ +AP F + +G V+F+ + G
Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773
Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
P P+I WF + S+ + + +D + L I++V G TC N G AS
Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832
Query: 596 TELIVEAP 603
L V P
Sbjct: 833 GRLKVRVP 840
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
++P PL +P + + C+ G P P + W +DG +L + +A +
Sbjct: 5923 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5982
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
++C+A N+HG T +G + P + E+ K + +
Sbjct: 5983 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 6042
Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
G E V +I GIP P V WYK+G ++ D K T + + I
Sbjct: 6043 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 6102
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+Y++EA+N G++ E +L +
Sbjct: 6103 NASPDDEGEYSLEATNKLGSAKTEGSLNI 6131
Score = 53.6 bits (123), Expect = 1e-06
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
+ +++ + V G P P I W + P + G + + + ++ G
Sbjct: 6423 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 6482
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
Y A+N G A+ + I V+ T N PL +N+ T +++ RV P
Sbjct: 6483 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 6535
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
P + W + I S I DG + +I N DSG Y CVA N AG+++ V
Sbjct: 6536 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 6595
Query: 922 TIDVE 926
T++ E
Sbjct: 6596 TVEAE 6600
Score = 53.2 bits (122), Expect = 2e-06
Identities = 26/93 (27%), Positives = 49/93 (52%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
I + D+G ++CVA N AG A+++ + VEA
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 6599
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559
Q AP+F ++L+ K G + C V+G P+P + + F +T ++ S +
Sbjct: 3083 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 3142
Query: 560 YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612
+D N +VI ++ ED ++ +A N+ G A+ST+++ VEAP+ + G + T
Sbjct: 3143 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 3198
Score = 51.6 bits (118), Expect = 6e-06
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
L V E + + AP F+ L+ K T V EC+V G P+P+++W I +Q
Sbjct: 2979 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 3036
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604
+ + V + I G +TC+A+N G + + L V EAP+
Sbjct: 3037 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 3088
Score = 50.0 bits (114), Expect = 2e-05
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
S+ + +V GYP P ITW++ + + Y D+D + I V D G +TC+
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 585 AKNAAGFASST 595
A N G AS++
Sbjct: 623 ATNEYGQASTS 633
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/235 (20%), Positives = 88/235 (37%), Gaps = 12/235 (5%)
Query: 1466 ETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
ET KV++ K + P L+++ + +++ I + P WY++G L+
Sbjct: 1965 ETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLED 2022
Query: 1525 AK--ATYENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNE 1578
K T +N + A N+ G E+S + + P++ +
Sbjct: 2023 GKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPK 2082
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ K E+ T I G P P V W N +E + E ++I K
Sbjct: 2083 SVTIKETETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIE 2140
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692
+ + A N+AG S + LKV P+ + +++ E + W LD
Sbjct: 2141 QTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 2195
Score = 48.0 bits (109), Expect = 7e-05
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
+E P R L + + E +V + V T V W +DG+ I P + F
Sbjct: 6034 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 6093
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
I L I N S DEGEYS ++ +A+ + ++ PP +
Sbjct: 6094 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 6153
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
+L+N+ V F+ + A V WF +G +I I++ + G L I D
Sbjct: 6154 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 6213
Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
L+DAGEY G++ +A+L V P ++ E + P T+ Y
Sbjct: 6214 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 6264
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437
P+PP + P I E+ + + W + + YV+E +E+ +W ++ NI +
Sbjct: 6275 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 6334
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
++NL+ SY+FR A N ISD S
Sbjct: 6335 CKVRNLELGKSYQFRVRAENIYGISDPS 6362
Score = 39.9 bits (89), Expect = 0.019
Identities = 45/203 (22%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXX 1534
P + + L N++ +E+ G+P P V WY+DG+++ K T E
Sbjct: 6038 PRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIH 6097
Query: 1535 XXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE------------DIK 1581
Y A N G +T + I + I ++E +K
Sbjct: 6098 HLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 6157
Query: 1582 QKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSH 1639
KH + ++ G P PEV W+ NG K+ I + S + I +
Sbjct: 6158 NKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLED 6217
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ +Y A N+ G++S L V
Sbjct: 6218 AGEYVATAKNSHGSASSSAVLDV 6240
Score = 39.1 bits (87), Expect = 0.034
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++
Sbjct: 6402 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 6461
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
Y + TL I E+ G + C AKN G A
Sbjct: 6462 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 6495
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472
E R A+ Y + + EAI L +G+ + +LD N W V+ K GWVP
Sbjct: 61 ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120
Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500
Y + Y Q++ +I+ + + ++
Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
+ G P P++ WYK+ +L D+ + + E + I ++ + + +YT A+N G +
Sbjct: 571 VTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQA 630
Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678
S +V + P + ++
Sbjct: 631 STSAFFRVLKVEKEAAPPAFVTKL 654
Score = 35.9 bits (79), Expect = 0.32
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 11/130 (8%)
Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDD----KITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
L + + I EI + PY +++ K+ TPP R + E T +TL
Sbjct: 6238 LDVTVPFLDSIKFNGEIDVT-PYLTEEYGFKKLNTASLPTPPD--RGPFIKEVTGHYLTL 6294
Query: 1885 KWTEPE-SNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA 1942
W + + P Y+IE + + K W+ + + V + + N++ FR+ A
Sbjct: 6295 SWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCK--VRNLELGKSYQFRVRA 6352
Query: 1943 ENTVGVSLPT 1952
EN G+S P+
Sbjct: 6353 ENIYGISDPS 6362
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1786 ITWFPSEKNGGS-PIIDYKVEIKQ-EGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYAR 1842
++W P+++ P + Y +EI++ K+W +++ L + +YQFR+ A
Sbjct: 6294 LSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAE 6353
Query: 1843 NEIGTSLP 1850
N G S P
Sbjct: 6354 NIYGISDP 6361
Score = 31.9 bits (69), Expect = 5.2
Identities = 35/193 (18%), Positives = 66/193 (34%), Gaps = 5/193 (2%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYC 692
P F +P + V++GS+ + IP P W G ++ E V +
Sbjct: 1140 PEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGA 1199
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S+L I + E + ++V E T E + V+ + + + +
Sbjct: 1200 SILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKESVVVEKQDLSSSEVQKE 1259
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYTLKAE 808
I +P T T T + T+ ++ K+ + E T+
Sbjct: 1260 IAQQVKEASPEATTTITMETSLTSTKTTTMSTTEVTSTVGGVTVETKESESESATTVIGG 1319
Query: 809 NSEGIAETSAVIT 821
S G+ E S ++
Sbjct: 1320 GSGGVTEGSISVS 1332
Score = 31.5 bits (68), Expect = 6.8
Identities = 48/230 (20%), Positives = 83/230 (36%), Gaps = 16/230 (6%)
Query: 180 EAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLT-----PIK 234
E ++ ESE+ ++TS + PEK+ D+K S T + +T P+K
Sbjct: 1508 ETTMTTEMTHESEE--SRTSVKKEKTPEKV---DEKPKSPTKKDKSPEKSITEEIKSPVK 1562
Query: 235 IERKEMEVSTPQHAETVD--GPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSW 292
E+ +V + T P+ T K P+ + +K
Sbjct: 1563 KEKSPEKVEEKPASPTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPKEK 1622
Query: 293 PPESI--KPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYED 350
PE KP + ++K K +K + P + P +D
Sbjct: 1623 SPEKADDKPKSPTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDD 1682
Query: 351 IVES--KKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDE 398
V+S KK+++ E++ KE PE+ + KS +K E +E
Sbjct: 1683 EVKSPTKKEKSPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEE 1732
>AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated
protein 89, isoform b protein.
Length = 8081
Score = 266 bits (652), Expect = 1e-70
Identities = 306/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%)
Query: 460 KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506
+H+ E+KG + L+ D NN YT K +E + +L + FEK T+EE
Sbjct: 3625 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3683
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
+ P+F+E L+ +G TV EC+V PQI +F+ ++ Q Q+ +D
Sbjct: 3684 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3742
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620
L I+ ED G + C A N AG A++ +L VE ++D ++
Sbjct: 3743 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3802
Query: 621 XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ G P F + ++ V E +L+C++ P P I W +G+E+
Sbjct: 3803 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3862
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734
+ + D + L NV + G Y A N G A PI++ ++ K E
Sbjct: 3863 VRAEHKDDGTL---TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3919
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790
P ++P+K +V GE+ +L ++ G P+P++ W KN KP + ++ D T +T
Sbjct: 3920 PDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3979
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+ K+ D Y +A N G + +TV+EP + P F I VKE T
Sbjct: 3980 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 4035
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
K +V+ P + W+++ + + + ++ D LVI + ++ D G+Y+ S
Sbjct: 4036 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 4093
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968
N AG ++ +T+ + +K +G ++L + T KWY + ++
Sbjct: 4094 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 4153
Query: 969 GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018
+I+Q D G + ++ + ++T+ V K ++P
Sbjct: 4154 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 4213
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077
F + L D V + +LEVEI + DV W ++G+ IK K E G+ + +L I
Sbjct: 4214 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 4269
Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ D GEYS +E+ E V PEI++ L V +G ATF +++
Sbjct: 4270 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190
V+W+K+G EI + + DG L+I + ++DA +Y S + G++ +A LT
Sbjct: 4330 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 4387
Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
V+ PE + L+P A V++ V WYK I + +
Sbjct: 4388 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 4445
Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302
+ +L I DD +Y V+ DA V+ P IV + + +G
Sbjct: 4446 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 4505
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361
L V+ P+ +W N K I +P D L I + DA YK+
Sbjct: 4506 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416
L + G+ AD +T+ P +P I++ ++ ++I E E +G+ + +
Sbjct: 4565 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 4621
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+E+ ++K I K + L+ SS ++A K+ E
Sbjct: 4622 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4680
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531
KI T KPLK+ + E+ E + P+ V WY++G+++K + +
Sbjct: 4681 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4736
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587
+ YK + N GE E+S + +++ I ED Q G
Sbjct: 4737 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4794
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+ + I+G P +V W ++ N + I + T+ + I + +YT+E
Sbjct: 4795 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4853
Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671
N +G + + +V +KP G
Sbjct: 4854 VINESGKAKSDAKGEVDEKPEIVRG 4878
Score = 248 bits (607), Expect = 3e-65
Identities = 294/1183 (24%), Positives = 489/1183 (41%), Gaps = 110/1183 (9%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G+ + +VEG P+ + W++ T + SQ ++ ++ L I D G +
Sbjct: 4127 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 4185
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
V ST VE+ + +TV P+F K Q
Sbjct: 4186 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 4221
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V +G+ ++LE + P+ D+ W G+EI D + D+ L I + ++
Sbjct: 4222 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 4274
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y+V A N GE I K K P+++ L V+QGE+ + +V G P
Sbjct: 4275 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 4329
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
+ W KN K + TK +GD + +V+D Y + N G A++SA +TV+
Sbjct: 4330 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 4389
Query: 824 EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+ ++ P ++ TVK+ T +V + PV + WY+N + I P+ N
Sbjct: 4390 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 4447
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
DG + L I N + D+ DYK V SN AG + A +T+ + + VK L+ + E +
Sbjct: 4448 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 4504
Query: 943 GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000
GK +L+ +T+ KWY N KEI+ D + +G D K +
Sbjct: 4505 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
+ D++ +T L VK P+ I+ L+D V LE+E + V W ++G
Sbjct: 4565 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 4624
Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109
+ + K ++ K L I ++ V D G+Y + +E+ +A + + + P+I
Sbjct: 4625 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4684
Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166
+ L++Q + +G A F +E +V+W+K+G EI+ ++ I+ D K Q L I
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4743
Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220
+ DDA Y + G ++ +A LTV++ ++ E +V V+I
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4803
Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
E DV W + +VI + I D R LII D EYT +++ K+
Sbjct: 4804 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4862
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
+ K EV E P+IV I G D V+ A P +W N + IK H +
Sbjct: 4863 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4920
Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I K L I + + D YK+ L N G D +T++ KPN+L+I
Sbjct: 4921 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4973
Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
++ +EP+ G +I + QE+ + K K ++ +L SS
Sbjct: 4974 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 5032
Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503
+ A V +D E V +K K PT PLK+ E + + L C
Sbjct: 5033 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 5092
Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
G P P+V W +DG L+ T + + Y+ A N+ G
Sbjct: 5093 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGS 5152
Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611
+ C V + + KP I +K + GD+ + G+P P + W+ NG
Sbjct: 5153 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGI 5209
Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
++ D + + + I++++ A N GT
Sbjct: 5210 PIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 5252
Score = 246 bits (603), Expect = 1e-64
Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G+ ILL + P+ + W +KG E V + ++ Y L+I + +
Sbjct: 4124 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 4179
Query: 705 EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y VV + + S V K EK P + L V +G ++L ++ G P
Sbjct: 4180 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 4239
Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+ + W KN +K + G+ + + KD G Y++ A N G E+ A + V
Sbjct: 4240 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 4298
Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+A+P + ++ TVK+ T +V + PV + WY+N + I ++T N
Sbjct: 4299 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 4349
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935
DG + L I N E D+ DYK V SN AG + A +T+ D K V L
Sbjct: 4350 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 4407
Query: 936 KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
+ ++G+T + V KWY N KEI ++ D
Sbjct: 4408 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 4464
Query: 995 GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
K +V D ++S L VK ++ L+D EV + A+L+VE N + ++ W
Sbjct: 4465 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 4524
Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103
++G+ I P + +L I + D EY +L DE SC V +
Sbjct: 4525 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 4584
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160
P+II L++Q V+ G+ EIE + V+W+K+G E+ + I++ ID K
Sbjct: 4585 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4644
Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
L+I ++D G+Y EV G++ + +TVE P I F L + + +A
Sbjct: 4645 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4702
Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271
+VE + V WYK I+ +F + K L+I+ DD Y VL
Sbjct: 4703 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4762
Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+A+S+ +L V+ + KIV + + +G+ + V Q P+ + W+ ++ +I
Sbjct: 4763 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4821
Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
+ ID + L I + DAG Y + + N G A + + +KP
Sbjct: 4822 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4881
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447
+EI ++ + E + + + QEI + K I K + +I + +
Sbjct: 4882 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4939
Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
++ N D+S V+K ++ + LK++ E + +EL G
Sbjct: 4940 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4993
Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
+P+ + WY++G++LK ++ Y+ + ND GEV
Sbjct: 4994 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 5052
Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ VV ++ K S + K GD + I G P PEVIW K+G L+
Sbjct: 5053 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 5112
Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670
D + + T+ +RI+ K+S +Y + A N AG TS +VT+ + ++PSKP+
Sbjct: 5113 KDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPK 5172
Score = 218 bits (533), Expect = 3e-56
Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+E L G+ V + G P+P +TW+ I S D DD +TL
Sbjct: 2754 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2812
Query: 570 IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626
I P+ G C A+N AG S T +I S+ SE +
Sbjct: 2813 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2872
Query: 627 --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ + P P F K K +G + EC + WL G+EI
Sbjct: 2873 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2932
Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733
I V + + + L + NV G YT + N G EA+L ++ + K EK+
Sbjct: 2933 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2992
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791
P+ I L+ + E V+L +V+G P+P ++W +NK + +++ +S +TI
Sbjct: 2993 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 3052
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849
++ +G YT AEN+EG ++T A +TV+ E P+F Q E+++ EK
Sbjct: 3053 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 3103
Query: 850 IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901
+ L V +P P + +Y +E I+ S I D N +VI+ + E D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 3162
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960
YK +A+NS G ++ +++T VE F + L+K+ +E + + +E + + +W
Sbjct: 3163 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 3221
Query: 961 YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014
+ + K +S + E+ + E D G + E+S V +
Sbjct: 3222 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 3281
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070
++ P F+R+L EVK + A L V + V W +DG+ ++ + + G
Sbjct: 3282 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 3341
Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124
+ I++ + D G+Y+C + E+ T A VV+ +PPE + +L +V +
Sbjct: 3342 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 3401
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
T +++ + V WFKD + I N H IQ L I D D G YSC
Sbjct: 3402 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 3461
Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232
E G + TA + SI FT +L P + D +TV I +V W+K K
Sbjct: 3462 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 3520
Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
I+++ F TL I++ +D YTC +AK+T + V+ P
Sbjct: 3521 PINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 3580
Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346
V + Y +++G L+V + P+P +W + I +H + ++ S +L
Sbjct: 3581 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3640
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
IK N D G Y + N G
Sbjct: 3641 IKDTNNADFGKYTCQATNKAG 3661
Score = 209 bits (511), Expect = 1e-53
Identities = 292/1248 (23%), Positives = 486/1248 (38%), Gaps = 138/1248 (11%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP+FV+ L+P G + +VEG P P++ WF+ I + +
Sbjct: 3574 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 3633
Query: 564 NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
N + TLVI++ D G +TC A N AG E + E + + E
Sbjct: 3634 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3681
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
E + P F + K + EG ++LEC++ P I + + + +++ +
Sbjct: 3682 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3734
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
+ D ++ L I N KK G Y AVN G+A+ LKI+ K V +
Sbjct: 3735 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3791
Query: 743 SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781
+ + Q E+V +L + V + I CK +P +
Sbjct: 3792 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3851
Query: 782 SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824
+G ++ + KD+G TL +AEN G A T ++T+E
Sbjct: 3852 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEG 3911
Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883
+ + E P F+ + V T L +++ P PS+ WY+N E + PS+ + +N
Sbjct: 3912 APKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3971
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940
D L +TN + D +Y+C ASN G +T+ + +V F K L + +
Sbjct: 3972 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 4029
Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
+E +T EC+ S T KW+ + + H E +G D G
Sbjct: 4030 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 4088
Query: 998 KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052
+ + D + V +P K L D V + +L VE+ + V W +
Sbjct: 4089 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 4148
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106
E + + + KL I + + D G Y +L +S + E VTV +
Sbjct: 4149 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 4208
Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P L +Q V KG E+E+ V+W+K+G EI+ ++ + K +L
Sbjct: 4209 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 4266
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217
I D D GEYS N A + +N + + PE + LVP A
Sbjct: 4267 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 4322
Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273
V++ V WYK I D + T + +L I +D +Y V+ DA
Sbjct: 4323 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 4380
Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
S+ L V++ + P+IV +K+G T V + P +W N K I
Sbjct: 4381 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 4439
Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
K K + D S SL I + D YK+ + N+ G AD +T+ PG
Sbjct: 4440 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 4493
Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443
+ ++ + + + E I + +EI ++ K Q I +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 4553
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+ + ++ +E D + + + + P + K L++ I+L
Sbjct: 4554 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 4609
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
G P+ V WY++GK+L A A +N+ YK N+
Sbjct: 4610 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4668
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G +S + ++ P IT + +K + E +V P V WYKNG +++ +
Sbjct: 4669 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4725
Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
+ I K T + IK R + Y I NTAG SS ++T+K
Sbjct: 4726 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4773
Score = 202 bits (494), Expect = 2e-51
Identities = 265/1127 (23%), Positives = 450/1127 (39%), Gaps = 106/1127 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G +L+ P+ +I W G+EI P + + D L I +
Sbjct: 4502 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 4557
Query: 705 EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
Y VV + +G A L +K KEP ++I+ L+ +V G + L + G+P+
Sbjct: 4558 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 4616
Query: 764 PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
T+ W KN K + K + + D + + V+D G Y ++ N G A +S
Sbjct: 4617 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4675
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876
ITVE P +P + Q IT E V N P I WY+N + I P S
Sbjct: 4676 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4726
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
I + +LVI N + D+ YK V N+AG++ A++T+ K K + K
Sbjct: 4727 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4784
Query: 937 SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991
E + +G ++ E + +W + IS + I + +
Sbjct: 4785 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4844
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D G V ++ K + PE +R L++ E+ E D + +VE+++ V
Sbjct: 4845 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4904
Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105
W ++ + IKP + + +K G + +L I + D +Y +L + + C + + +
Sbjct: 4905 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963
Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159
P +I+ L++ V + ++++ +++W+K+G E++ + +
Sbjct: 4964 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 5023
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214
+ L I D G Y +GN K +++ V+ + F+ +T+
Sbjct: 5024 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 5083
Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267
LT++ I E +V W K V++ ++ T+ ++ TL IR + D +Y
Sbjct: 5084 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYR 5143
Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ +T+ KV V E PK V + G V + P+P +
Sbjct: 5144 VTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ 5203
Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
W +N IK + T + + LTI+ V D G K +N G D +
Sbjct: 5204 WFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 5262
Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437
G + L WD G+ I V+ EW K I T
Sbjct: 5263 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 5322
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480
T I+N + + R + E DI +ET Y+V ++E K +
Sbjct: 5323 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 5381
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535
+P + PL++ T + I L+C +P+ V WY+DG L+ T YE
Sbjct: 5382 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 5441
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587
Y+C+A N HG + TSC V ++ ++ V E K V G
Sbjct: 5442 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 5501
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646
D + + + G P PE+ WY+NG L N I T+ + + + + E S Y E
Sbjct: 5502 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685
A N T T+ V++ L +KP EG P + E+S SV++
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 5608
Score = 180 bits (439), Expect = 8e-45
Identities = 143/525 (27%), Positives = 224/525 (42%), Gaps = 45/525 (8%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+++ P FV KLR K +G + FEC+VEG+P P++ W ++PS DF++ YD
Sbjct: 642 EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622
A L IR+ P+D G +T +N G S EL V+A P +H
Sbjct: 702 T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
+ P F + DEG ++ + + P P+I W G+ + E +
Sbjct: 746 ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
E + C +L I +V + +G T NR G AS LK++ PP +PL+
Sbjct: 797 ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798
V++ +V+ V G P PT+T+ K +K + + I+I K
Sbjct: 852 DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+G KA+N G AE+ A +TVE+ EE+ P F+ ++ TVK V
Sbjct: 912 HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
NP P +TW+ N + + + N + +T +DS +G C A N+ G+
Sbjct: 972 NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029
Query: 919 AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
AR V + EK FV+ L ET + TV+ E + + WY +E+ D
Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
EI + D G I+ + + E S K T+
Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTV 1133
Score = 177 bits (430), Expect = 9e-44
Identities = 287/1251 (22%), Positives = 485/1251 (38%), Gaps = 155/1251 (12%)
Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
V+ L P G + + P+ +I W++ I PS Q D DN LVI +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 4552
Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
+DA + V + G + D +TV L
Sbjct: 4553 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 4586
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691
P K + Q V GS I LE P+ + W G+E+ ++ I+ D + Y
Sbjct: 4587 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4645
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750
VL+I + G Y V N G A+ + + EP ++PLK + +GE
Sbjct: 4646 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4698
Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ S + PR + W KN KP + DT ++K D Y +
Sbjct: 4699 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4757
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866
EN+ G AE+SA +TV++ + I + E V KG K+V V P + W
Sbjct: 4758 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4812
Query: 867 YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
R+ +IS + I + D L+I + D + D+G+Y N +GK+ A+ +D
Sbjct: 4813 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4870
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984
EK V+ L+ + E EG + + + S V KWY N +EI H E + G
Sbjct: 4871 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4929
Query: 985 XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
D G V+ D ++S L VVK + + + L+D +V+E L+V
Sbjct: 4930 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4989
Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095
++ + W ++G+ +KP + + FE++ + L I ++ D G Y +L D+
Sbjct: 4990 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 5049
Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143
+VV + ++ L++ +V +G+ T + + G+ V W KDG
Sbjct: 5050 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 5108
Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193
+Q + I ++ +DG L+I D G+Y N S C +T E+
Sbjct: 5109 VVLQKDDRITMRVALDGTAT-LRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQ 5167
Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244
PS F + L +P + + + V +P TL W+ I+ ++ TL
Sbjct: 5168 PSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ--WFLNGIPIKFDDRITLDDMADG 5225
Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
I DV++ KC E+ E C + + +PP+ +
Sbjct: 5226 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 5285
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354
RI G + + A P EW + K I+ HT + ++D + + I E +D
Sbjct: 5286 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 5344
Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
G+Y N G A+ + V IL+ + + + D+ N G
Sbjct: 5345 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 5401
Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458
+ V+ + W + ++TSIQ L N S +R A N
Sbjct: 5402 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 5461
Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
+ S + +E K + P K L ++ + + L C G P P++ WY
Sbjct: 5462 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 5521
Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
R+G+ L+ T + Y+C A N HG+ +T +Q
Sbjct: 5522 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 5581
Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+KP ++ +S+ + + + E VT G+P P V W K+G L
Sbjct: 5582 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 5637
Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
D + + + V +RIK Y A+N G+++ + +++ D
Sbjct: 5638 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5688
Score = 176 bits (429), Expect = 1e-43
Identities = 260/1229 (21%), Positives = 496/1229 (40%), Gaps = 133/1229 (10%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VAT 567
AP+F + L+ + ++ E +V G P + WF+ + + +M + + V T
Sbjct: 3188 APVFEQGLKKTSVKEKEEIKMEVKVGG-SAPDVEWFKDDKPVSEDGNHEMKKNPETGVFT 3246
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
LV+++ DAG +T A N AG T E EA ++
Sbjct: 3247 LVVKQAATTDAGKYTAKASNPAG----TAESSAEAEVTQS-------------------- 3282
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
LE PTF ++ V L + +P+P + WL G+ + D + +A
Sbjct: 3283 -LE--KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEG 3339
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
Y +K ++ G Y A N GEA + PP+ +E L + V+
Sbjct: 3340 SGSYSITIKDARLE--DSGKYACRATNPAGEAKTEANFAV-VKNLVPPEFVEKLSPLEVK 3396
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGV 802
+ ES LS +VVG P P++ W K++ P+ + ++ + S+TI ++ D G+
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQ-GDVGI 3455
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
Y+ +A N G A T+A + ++ PP F + + + V+E+ T+ L V PVP
Sbjct: 3456 YSCRARNEAGEALTTANFGIIR----DSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVP 3511
Query: 863 SITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
++ W+++++ I+ S ++ + L I E D G Y C A+N AG++ A
Sbjct: 3512 NVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGE-DVGVYTCKATNEAGEAKTTAN 3570
Query: 921 VTI--DVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ + ++E FV+ L K YE E+GK +++ + KW+ + I+ +D++ +I
Sbjct: 3571 MAVQEEIEAPLFVQGL-KPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIA-IDNQHVI 3628
Query: 977 Q---EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
+ E D G C ++ V + IP++ + Q E +V
Sbjct: 3629 EKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAE----EV 3684
Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
L +E ET V E D +++ K NK H + + +N + G++ +
Sbjct: 3685 KPLFIEPLKETFAV--EGDTVVLECKVNK-----ESHPQIKFFKNDQPVEIGQHMQLEVL 3737
Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
E ++T+ E + + + VN KA +L +IQF+ ++
Sbjct: 3738 EDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADL--------------KIQFAAKVE 3783
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
+ + +L ++ G++ VG++ + T + F + L V
Sbjct: 3784 EHVTDESGQL-------EEIGQFET-VGDTASSKTDT-GRGAPEF-VELLRSCTVTEKQQ 3833
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL 1271
A L ++ E + W K+ +E + + D TL T+ D EY C
Sbjct: 3834 AILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAE 3893
Query: 1272 DAKSTTKLKVEVV---EFPPKI----VDYEREYR---IKRGSDVTLLVDYQAFPQPNDEW 1321
+ + + ++ E PKI D+ + + + G L P+P+ +W
Sbjct: 3894 NEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKW 3953
Query: 1322 IVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADVEMNVTIL 1378
N + +K K ++D + LT+ + D Y+ N G +DV + V
Sbjct: 3954 YKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEP 4013
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQ 1437
+ +P + I E + +G + + + + + + ++ TQ
Sbjct: 4014 AQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQ 4073
Query: 1438 TS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTE 1494
I++ KT+ +R N+ ++++ + T + S T ++K L ++
Sbjct: 4074 RLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKGLTDVNVT 4125
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYK 1549
I L+ G P+ V WY+ + + +++ T E+ Y+
Sbjct: 4126 QGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYR 4184
Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIEGIPPPEV 1604
+ D VE+S V + K IS K Q G ++ IEG P +V
Sbjct: 4185 VVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEG-KPKDV 4242
Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYKNG+++++ K ++ + + I + + +Y++ A+N AG + + V
Sbjct: 4243 KWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSA 4300
Query: 1665 KPSKPEG--PVIMREISRESVTIEWKPPL 1691
KP G P +++ + ++ K P+
Sbjct: 4301 KPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Score = 171 bits (417), Expect = 4e-42
Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%)
Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563
MAP F+ K++ G + FEC V W + I+ ++ +
Sbjct: 2885 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2944
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
LV+ V PEDAG +TC+ +N AG + L V L +
Sbjct: 2945 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2993
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
P F + + ++LEC+++ P+P ++WL + I + S+
Sbjct: 2994 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 3040
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
+ES + + IT+ + +G YT +A N EG + L T + E P + L++
Sbjct: 3041 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 3095
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792
+ GE ++LS V G+P+P + + ++ K + TK +TH ++
Sbjct: 3096 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 3154
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+D Y A NS G A +++ IT + E P+F ++ +VKEK IK+
Sbjct: 3155 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 3208
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911
+V P + W+++++ +S + E + ++ + D+G Y ASN
Sbjct: 3209 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 3267
Query: 912 AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
AG +SS A VT +EK TFV+ L + E T+ + + S +W + + +
Sbjct: 3268 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 3327
Query: 969 GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020
I ++ D G C + + + VVK + PEF+
Sbjct: 3328 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 3387
Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077
KL EVKEK+ L V+ + + V W +D I N + +K+ + L I
Sbjct: 3388 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 3446
Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131
+ D G YSC R+E+ TA ++ +PPE +L+ +V + + T ++++T
Sbjct: 3447 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 3504
Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182
G + V WFKD I N HI +G L I +D G Y+C E G
Sbjct: 3505 VIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 3564
Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237
+K TA + V+E + F L + V A L V + + +V W+K I+
Sbjct: 3565 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 3623
Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286
+ + TL+I+ D +YTC + K T +LK+ F
Sbjct: 3624 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3683
Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344
P ++ +E G V L P ++ N + ++ +H + + + +
Sbjct: 3684 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3743
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
LTI+ + D G Y+ N G A+ ++ I
Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 169 bits (412), Expect = 1e-41
Identities = 255/1135 (22%), Positives = 433/1135 (38%), Gaps = 126/1135 (11%)
Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
TF K K Q + EG + P + W G+EI P+ + ++D Y V
Sbjct: 4684 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4741
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
+K N + TY +V N GEA L +K + ++++ L+ +V +G ++
Sbjct: 4742 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4799
Query: 755 SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P + W ++ + A + K D T+ + I+ +KD G YT++ N
Sbjct: 4800 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4857
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
G A++ A V+E E + + I + E V+ PV + WY+N+
Sbjct: 4858 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4909
Query: 871 EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
+ I P+ + G + EL I + D DYK V SN+AG A +T+ V
Sbjct: 4910 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4968
Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984
+ K + EE + V L+ + KWY N +E+ G E + G
Sbjct: 4969 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 5028
Query: 985 XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033
D G + ++ K + S +V K + P F+ L+D EV+E D+
Sbjct: 5029 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 5087
Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
L+ I E +V+WE+DG +++ L IR+ D G+Y +
Sbjct: 5088 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAK 5147
Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142
+E+ +A +VTV E P+ + L+ G+K F +++ ++WF +
Sbjct: 5148 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLN 5207
Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193
G I+F + I L DG L I D +D G C N T E +
Sbjct: 5208 GIPIKFDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 5266
Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244
LR P VP D + V P + T +V W+K IE T +
Sbjct: 5267 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 5325
Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290
+ V I I E D Y CV ++ A++ +VE++E + PKI
Sbjct: 5326 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 5385
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349
+ + G + L A P+ + W + ++ T + +A+L I
Sbjct: 5386 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 5445
Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
D G Y+ N G + +V + K + + W + G+
Sbjct: 5446 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 5502
Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455
S + V +W ++N +T +TS +L N S +R A
Sbjct: 5503 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 5562
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509
N + T + +T+ KP L +++ I+L C G+P
Sbjct: 5563 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 5622
Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561
P V W +DG L + ++ + N Y+C+A N++G T
Sbjct: 5623 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5682
Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
S VV Q P T+ D++ G + ++ P PE++WYK+G
Sbjct: 5683 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5740
Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I+ + + + + I Y + A+N +GT+ + T V P
Sbjct: 5741 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5795
Score = 156 bits (379), Expect = 1e-37
Identities = 258/1109 (23%), Positives = 438/1109 (39%), Gaps = 156/1109 (14%)
Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
F++ L+ + +G +F + PR + W++ IKP+ F + D LVI+
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4743
Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
+DA T+ V +N AG A S+ +L V+ I++G
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4785
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+ + Q V +G+ ++ E ++ PE D+ WL I N ++ + D Y
Sbjct: 4786 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4835
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
++ ++K G YTV +N G+A K E P+++ L+++ + +G+
Sbjct: 4836 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4889
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
+ +V P + W KN++ +K L K G + ++ D Y +
Sbjct: 4890 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4948
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N+ G ++SA +TV +P ++ +++ V+E ++L +V P I WY+
Sbjct: 4949 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 5002
Query: 869 NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926
N + + P ++ E+ E +T S+ D G Y+ V N G+ G+ V +
Sbjct: 5003 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 5062
Query: 927 K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975
K F+ L K E EEG + L+C + + W + + D +
Sbjct: 5063 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 5121
Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026
+G D+G + K++ S K T+ P+F+ L+
Sbjct: 5122 ALDG-TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 5180
Query: 1027 EVKEKDVAILEVEINSETADVV-WERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
D V++ + W +G IK + D G+ L IR+ D
Sbjct: 5181 AALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYC-LTIRDVREEDF 5239
Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128
G CI ++E+ T E TV E PP L ++++ G+ E
Sbjct: 5240 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 5298
Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
+ A V WFKDG +I+ + H ++ T+DG ++KI + D G Y C E+G
Sbjct: 5299 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 5357
Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
++ A VE P IN L E V L+ ++ V
Sbjct: 5358 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 5414
Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
WYK + D+ + TL I TE+D Y CV +A T V V+
Sbjct: 5415 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 5474
Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334
P + V E E RG TL P P +W N ++++ T
Sbjct: 5475 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 5534
Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386
+ S D S SLT+ + +D GIY+ EN G A V+M + +KP GK
Sbjct: 5535 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437
P ILE+ S+ N+ E + TG N ++ + I+ + EW + + Q
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490
I+N + +R A NE + S TT+ + + + T Q P + +
Sbjct: 5654 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5709
Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+ T + ++L C P P++ WY+DG
Sbjct: 5710 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5738
Score = 149 bits (361), Expect = 2e-35
Identities = 173/749 (23%), Positives = 292/749 (38%), Gaps = 93/749 (12%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S E + F+ L+ +G + +C + G P P++ W + +++ M
Sbjct: 5064 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 5123
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
D ATL IR D G + AKN AG A+S ++ V ++ G + +
Sbjct: 5124 DGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTV----TEQGEQPS---------- 5169
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
P F K G ++ +P+P + W G I D+ I++
Sbjct: 5170 ----------KPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITL 5219
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734
+D + YC L I +V++ GT +A N G + G + P
Sbjct: 5220 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
P+ PL + G+ + + V NP + W K+ K ++ T+ +K
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 794 --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846
P + D GVY A N G AET A VE E EE P ++ TV
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
I+L +V P S+ WY++ + + ++ + + N +E D G Y+C
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 5456
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956
VA+N+ G + V + V K K ++ + T + G + L+C +
Sbjct: 5457 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 5516
Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007
KWY N + + R +I+ D G+ +C K Q T+
Sbjct: 5517 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 5575
Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055
+ + +T P+FI +L D V +V LE ++ V W +DG +
Sbjct: 5576 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 5635
Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101
I+ + ++ E + +L I+N +VHDEG Y C+ +E+ +A V
Sbjct: 5636 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5695
Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158
PP ++ + + +G E ++ + W+KDG+ + S+ IQ+++ DG
Sbjct: 5696 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5755
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
L I C DD G Y N TA
Sbjct: 5756 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5783
Score = 143 bits (346), Expect = 1e-33
Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+ + AP L K G ++ C+V+ PR + W++ ++ + Y++D
Sbjct: 5377 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 5436
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
ATL I + ED G + CVA NA G +++ + V+ P + E
Sbjct: 5437 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 5483
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
G P F+K + D G L+C + P P+I W G+ +
Sbjct: 5484 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 5534
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733
IE+ CS L + EG Y A N G+A +L K K E +
Sbjct: 5535 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
PP+ I L M V G + L +V G P P++ W K+ P+ ++
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845
+ +K V DEG Y A N G A T + + +++ ++PP F + ++
Sbjct: 5654 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5713
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
E +KL +V +P+P + WY++ I++PS+ I + + + ++ D G Y+
Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5773
Query: 906 CVASNSAGKSSHGARVTI 923
+A+N +G + T+
Sbjct: 5774 VIATNPSGTAQDKGTATV 5791
Score = 141 bits (342), Expect = 4e-33
Identities = 270/1279 (21%), Positives = 483/1279 (37%), Gaps = 84/1279 (6%)
Query: 151 VTLEKSDLFDSQEDESKPD-VSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKI 209
+T E + S + E P+ V + P++ ++ KS K I E + K + +V EK
Sbjct: 1515 MTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKP 1574
Query: 210 NVPDDKETS-QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXX--X 266
P KE S + P S K+S+ +K K+ + E + P+
Sbjct: 1575 ASPTKKEKSPEKPASPTKKSE-NEVKSPTKKEKSPEKSVVEELKSPKEKSPEKADDKPKS 1633
Query: 267 XXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQ 326
E S K +KS K S KP +K K +K
Sbjct: 1634 PTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDDEVKSPTKKEKS 1693
Query: 327 VFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRK 386
+ P + + P S + V+S K+++ E++ KE PE+ K
Sbjct: 1694 PQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVK 1753
Query: 387 SSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLY 446
S +K ++ ++ +K +P + +PV++ D V + T + + + E
Sbjct: 1754 SPTKK-EKSPEKSAEEKPKSPTKKESSPVKM-ADDEV------KSPTKKEKSPEKVEEKP 1805
Query: 447 ILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQ 506
T + +K EE P + ++ T+ + EK + P EKP S
Sbjct: 1806 ASPTKKEKT--PEKSAAEELK-SPTKKEKSPSSPTKKTGDESKEKSPEKPE-EKPKSPTP 1861
Query: 507 SMAPIFVEKLRPKHTPDGST-----VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
+P K + +P+ + + +++ + + F +++ + + + + D
Sbjct: 1862 KKSPPGSPKKKKSKSPEAEKPPAPKLTRDLKLQTVNKTDLAHFE--VVVEHATECKWFLD 1919
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
+ T V +D F C + + F S T ++ + GS T
Sbjct: 1920 GKEITTAQGVTVSKDDQFEFRC-SIDTTMFGSGTVSVVAS---NAAGSVETKTELKVLET 1975
Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
E P F+ K + V +G + ++ ++A+ P W G ++ D
Sbjct: 1976 PK------ETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGN-LLEDGKNG 2026
Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
V I+++ + S L I N + G TV A N G + L + P V++
Sbjct: 2027 VTIKNEENK--SSLIIPNAQ--DSGKITVEASNEVGSSESSAQLTVNP-PSTTPIVVDGP 2081
Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
KS+ +++ E+ A + G P PT+ W N K V+ T + T + LK K E
Sbjct: 2082 KSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQ 2141
Query: 802 VYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-R 858
T+K A+NS G A + V E N + P F ++ + E ++ +
Sbjct: 2142 TGTVKVTAQNSAGQDSKQADLKV----EPNVKAPKFKSQLTDKVADEGEPLRWNLELDGP 2197
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
+P ++W N + ++ S+T+ G+ + I E+ SG A N+AG+
Sbjct: 2198 SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEM-SGTLTAKAKNAAGECET 2256
Query: 918 GARVTID--VEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHRE 974
A+VT++ +K FV+ Q T E T + + WY N K++ + +
Sbjct: 2257 SAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVK 2316
Query: 975 I--IQEGRXXXXXXXXXXXXDVGVIKCIV-----KDQETSTMLVVKET-IPEFIRKLQDF 1026
+ + E G I+ K Q T+ + V K+T +P+F + D
Sbjct: 2317 VKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDDR 2376
Query: 1027 EVKE-KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
+VKE +DV V W +GE + N +K G + I + G
Sbjct: 2377 QVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGE-HTIEISAVTPEQAG 2435
Query: 1086 EYSCIL------RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE--IELTKGDALV 1137
E SC + V V P L+++ + +G + + + K +
Sbjct: 2436 ELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKI 2495
Query: 1138 RWFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYS----CEVGNSKCTAILTVE 1192
W KDG EI H ++ + KL I L+D G + E G ++C+A L V
Sbjct: 2496 TWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVV 2555
Query: 1193 E--PSIN--FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDV 1248
+ P F + L +T + D T V WY ++ TE + +
Sbjct: 2556 KGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNAN 2615
Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDV 1305
T+ I T D + CV + + + P V++E + + G +
Sbjct: 2616 GVYTMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTL 2675
Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
L P+P W VN K +++ ++ K + + ++TIK + +G N
Sbjct: 2676 KLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINE 2735
Query: 1366 CGHADVEMNVTILDKPSPP 1384
G A E + +L + PP
Sbjct: 2736 YGKATSEATLLVLPRGEPP 2754
Score = 139 bits (337), Expect = 2e-32
Identities = 180/762 (23%), Positives = 288/762 (37%), Gaps = 105/762 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F L + P G + EC V+ P ++ WF+ I+ + ++ D +
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I D G + CVA N G A T+ + + +H E +
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAE--TQATYQVEILEHVEE------------EKRREYA 5382
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
I P K V+ G I L C++ AIP + W G + D S+ E D
Sbjct: 5383 PKINPPLEDKT----VNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG- 5437
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQVIEPLKS 743
+ L I + + G Y VA N G + + +K E E P + L
Sbjct: 5438 --TATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVD 5495
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKALPTKSDGDTHSITILKPKKVK 798
+ +G+S L V G+P P I W +N N P + T DG S+T+ +
Sbjct: 5496 LWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC-SLTV-NESTMS 5553
Query: 799 DEGVYTLKAENSEGIAETSAVITV-------EEPTEENAEPPLFINRFQEITVKEKGTIK 851
DEG+Y +AEN+ G A+T A V E+P + +PP FI +++V I
Sbjct: 5554 DEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVID 5613
Query: 852 LVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVAS 909
L +VT P PS+ W ++ +I S N + + +L I N D G Y+CVA+
Sbjct: 5614 LECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVH-DEGTYRCVAT 5672
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQT--SHTVST 958
N G ++ + V +D + V + T EG+ + LEC+ S
Sbjct: 5673 NENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEM 5732
Query: 959 KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVV 1012
WY + ++ D +I + D G+ + I + Q+ T V
Sbjct: 5733 VWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVK 5792
Query: 1013 K------------------ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
K P+ + L++ + EK L + + + + W +DG
Sbjct: 5793 KLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDG 5852
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVTVVELPP 1107
E + P E + +L + + + D G Y C+ + SC V + P
Sbjct: 5853 ERVFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKP 5912
Query: 1108 EII-------------TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152
I T L ++ G+ TFE L G+ ++W KDG E+ I
Sbjct: 5913 RDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFEC-LPFGNPFPSIKWLKDGLELFSDEKI 5971
Query: 1153 QL--TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
++ DG Q+L + D G + C N TA E
Sbjct: 5972 KMEAAADG-TQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Score = 133 bits (321), Expect = 2e-30
Identities = 185/819 (22%), Positives = 326/819 (39%), Gaps = 81/819 (9%)
Query: 936 KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989
K + ++G + + EC T V KW + KEI + + EG
Sbjct: 2894 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2953
Query: 990 XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036
D G CIV KD +T+ V++ + PEFI LQD K + +L
Sbjct: 2954 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 3013
Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
E ++ E V W D + I + E + ++ I ++ + +G+Y+CI +
Sbjct: 3014 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 3071
Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143
T++ +TV P LQN++++ G K + KG + K
Sbjct: 3072 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 3130
Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195
++I S+ I + D ++ I +D Y NS TA T VE P
Sbjct: 3131 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 3190
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253
L+ V + + V++ DV W+K K V ED + + TL
Sbjct: 3191 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 3247
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309
++++ D +YT + T + + EV + P V +K TL V
Sbjct: 3248 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 3307
Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P+ EW+ + + ++ H ++ S S S+TIK D+G Y R N G
Sbjct: 3308 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 3367
Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
A E N ++ PP K + LE+ + T + VE+ + DT
Sbjct: 3368 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 3422
Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
I ++ + QT++ +L N + + Y+ + + + TT + +I+++
Sbjct: 3423 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 3480
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534
P + L+ + E ++L G P P V W++D K + AK
Sbjct: 3481 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT 3540
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593
Y C A N+ GE +T+ + +Q++ + + +K + + G +
Sbjct: 3541 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 3600
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651
+EG P PEV W+K+G + D ++ I K + + + IK+ + KYT +A+N A
Sbjct: 3601 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3660
Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686
G LK+ ++K + E + E +E+ +E
Sbjct: 3661 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3699
Score = 131 bits (316), Expect = 6e-30
Identities = 145/606 (23%), Positives = 250/606 (41%), Gaps = 53/606 (8%)
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P PDI W ++ DE + + D + I V+ G YT +A N
Sbjct: 570 KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626
Query: 716 EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
G+AS ++ EKE PP + L+ ++G+ + +V G P P + W +++
Sbjct: 627 YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686
Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
P++ + DG T + I + + D GVYT+K +N G E+ A + V+ ++N
Sbjct: 687 PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
P F + + E ++ + +T +P P I W+ N + +S SE + + L
Sbjct: 746 VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948
I +V D G C SN G +S R+ + V TF K L+ +E TV+
Sbjct: 806 TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863
Query: 949 ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
E S T K+ +G + EI+ +G G I +++
Sbjct: 864 EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923
Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
E+ L V++ + P F++ ++D VK + A+ E + + +V W +G
Sbjct: 924 HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104
+ E H KL I S G C + R E+ V + +
Sbjct: 984 HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+
Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101
Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + ++DAGE NS + A LTV++ PEF L P + LTVE
Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPF-----APEFDLRPVS----LTVE 1152
Query: 1220 IPDETL 1225
E +
Sbjct: 1153 KGSEAV 1158
Score = 130 bits (313), Expect = 1e-29
Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K +++ P F + L G + +C V G P P+I W+R +++ +
Sbjct: 5477 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 5536
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
D +L + E D G + C A+NA G A + V+ L
Sbjct: 5537 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 5582
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ EG PP F + V G+ I LEC++ +P P + W G ++ D
Sbjct: 5583 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5640
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732
+ E+ +Y L+I N EGTY VA N G A+ +++ G
Sbjct: 5641 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5698
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789
+PP+ + + +G+ + L +V +P P + W K+ A+ T SD S+
Sbjct: 5699 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5754
Query: 790 ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832
T+L P V D+G+Y + A N G A+ TV++ P + A +
Sbjct: 5755 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5814
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890
P + + I + EK + +L + + +P P+I W+++ E + P + ++ DG EL
Sbjct: 5815 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5873
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
V+ + + D+G Y+CVA N+ G + V +
Sbjct: 5874 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5905
Score = 127 bits (306), Expect = 1e-28
Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+ + AP +E L P+ + + C+ G P+P I WF+ + P Q+ D
Sbjct: 5810 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5869
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
V LV+ +DAG + CVA+N G S+ T V D
Sbjct: 5870 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5915
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
+ I EG P F+ + G + EC P P I WL G E+ DE I +
Sbjct: 5916 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5975
Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731
+D L +++V EG + VA N G AS L I+ GE
Sbjct: 5976 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 732 KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782
E P++ L +M + +G V + G P PT+ W K+ + + K +
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834
+ H + I+ DEG Y+L+A N G A+T + + P +A+ PP
Sbjct: 6093 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 6151
Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893
F+ + + V V +P P + W+ N + I P I Q+ G + L+I
Sbjct: 6152 FVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 6211
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ E D+G+Y A NS G +S A + + V + +K
Sbjct: 6212 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 6249
Score = 121 bits (292), Expect = 5e-27
Identities = 224/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
+P+ L D YT E I++ + E P V L P+G
Sbjct: 4839 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4891
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
F+ +V P Q+ W++ IKP+ + L I +D + V NA
Sbjct: 4892 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4950
Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
AG S+ L V P I++G+ ++P+
Sbjct: 4951 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4983
Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
+ L+ ++ IP+ I W G+E+ PD + E L I + KK G Y
Sbjct: 4984 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 5040
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764
VV N +GE V+ +K+ + P + PLK V +G+ + L + G P P
Sbjct: 5041 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 5100
Query: 765 TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
+ W K+ ++ + DG T ++ I KK D G Y + A+N G A +
Sbjct: 5101 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSAKK-SDIGQYRVTAKNEAGSATSDCK 5158
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+TV E E+ ++P F+ + + +V P P++ W+ N I + I
Sbjct: 5159 VTVTEQGEQPSKPK-FVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRI 5217
Query: 880 T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928
T + N L I +V E D G KC+A N G + H D+
Sbjct: 5218 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985
G + +EC + T +W+ + K+I H EI
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030
D+GV C+ ++ ET V +E P+ L+D V
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
L ++++ A VVW +DG ++ + +E+ G L I +++ D G Y
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 5455
Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
C+ + SC+ V V + P L + ++G+ T + +T GD
Sbjct: 5456 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 5514
Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
++W+++G ++ I+ + DG L + + + D G Y CE G +K A
Sbjct: 5515 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 5573
Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233
V E+P ++ + P+FIL ++ L I E V W K
Sbjct: 5574 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 5632
Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283
+ + +F ++ K L I+ T D+ Y CV + +TTK V +
Sbjct: 5633 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5692
Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
PP+ + R G + L A P P W + I+ + S+
Sbjct: 5693 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5752
Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
A+L I D GIY++ N G A + T+ P G
Sbjct: 5753 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5799
Score = 116 bits (278), Expect = 2e-25
Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
EKP +E P F+ +L G+ + EC+V G P P + W + + F+
Sbjct: 5585 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5643
Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ V L I+ D GT+ CVA N G S+TT+ V D G V
Sbjct: 5644 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5698
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
PP F+ K EG + LEC++ A P P++ W G + P
Sbjct: 5699 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5744
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
+ I +++ D + L I + +G Y V+A N G A +K +G +
Sbjct: 5745 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5801
Query: 733 -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778
+ P+++EPL+++ + + +S L + G+P+PTI W K+ + P L
Sbjct: 5802 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5861
Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829
D ++ +D G Y AEN+ G A TS + V +P +
Sbjct: 5862 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5921
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+ P F K ++ NP PSI W ++ + E I + +
Sbjct: 5922 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5981
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944
+I + + + G ++CVA+N G +S A + I+ ++ + L + + E EE K
Sbjct: 5982 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 6037
Score = 114 bits (274), Expect = 7e-25
Identities = 135/593 (22%), Positives = 242/593 (40%), Gaps = 45/593 (7%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
P++ L+ Q VNK + A FE+ + +WF DG EI + + ++ D + + +
Sbjct: 1885 PKLTRDLKLQTVNKTDLAHFEVVVEHATEC-KWFLDGKEITTAQGVTVSKDDQFE----F 1939
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ET- 1224
C +D S V A +VE + L P+ P TD +E+ +T
Sbjct: 1940 RCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTV 1999
Query: 1225 -LDVT--------WYKKKSVIEDTEK-FTLISDVKKRTLIIRKCTEDDQC--EYTCVLLD 1272
+DV WY+ +++ED + T+ ++ K +LII + + E + +
Sbjct: 2000 QMDVIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGS 2059
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
++S+ +L V P +VD + IK FP P +W +N KI+++ +
Sbjct: 2060 SESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESR 2119
Query: 1333 H--TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
T + D + ++ K+E T G K+ +N+ G + ++ + P + L
Sbjct: 2120 TITTIKTEDVYTLKISNAKIEQT--GTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQL 2177
Query: 1391 --EIDSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKT 1445
++ + W+ E + T + +++ Q + ++ + V + +I K
Sbjct: 2178 TDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKP 2237
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
S A A N A E KV + P + +N T E ++ + I
Sbjct: 2238 EMSGTLTAKAKNA-----AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIV 2292
Query: 1506 GGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCI---AFNDHGEV 1559
G P P VTWY + KKL + K Y + I A N G+V
Sbjct: 2293 TGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKV 2352
Query: 1560 ETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
+ + + + +K + +N D +Q K G++ TA +EG P P V W NG +
Sbjct: 2353 QATAQLKVDKKTEVPKFTTNMDDRQV-KEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHP 2411
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL---KVYDKPS 1667
+T K+ I I + + + + EA+N G+ +V L KV D P+
Sbjct: 2412 NITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPT 2464
Score = 112 bits (269), Expect = 3e-24
Identities = 206/1012 (20%), Positives = 379/1012 (37%), Gaps = 71/1012 (7%)
Query: 726 KIKTGEKEP-PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKS 782
K EK P P++ LK V + + + +VV W + K + T S
Sbjct: 1875 KSPEAEKPPAPKLTRDLKLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVS 1932
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
D + G ++ A N+ G ET + V E +E +P F ++ +++
Sbjct: 1933 KDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPE-FTDKLRDM 1991
Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDS 901
V + T+++ +P+ WY+N ++ + +T + L+I N DS
Sbjct: 1992 EVTKGDTVQMDVIALHSPL--YKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DS 2046
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILECQTSH--TVST 958
G ASN G S A++T++ T V KS +E +T + S +
Sbjct: 2047 GKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTV 2106
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKE 1014
KW N+K + I+ G +K ++ Q++ L V+
Sbjct: 2107 KWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEP 2166
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEIIKPKKNKYDFEKRGH 1070
+ P+F +L D E + +E++ S +V W +G+ + +
Sbjct: 2167 NVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDG 2226
Query: 1071 IRKLYIRNTSVHDEGEYSCILRDES--C--TAEVTVV--ELPPEIITRLQNQKVNKGNKA 1124
+ I G + ++ + C +A+VTV PE + QN +
Sbjct: 2227 TYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESV 2286
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV- 1180
F +T K V W+ + ++ S +++ + K ++I ++ G E
Sbjct: 2287 KFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAE 2346
Query: 1181 ---GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
G + TA L V++ + FT + + V D T + V W
Sbjct: 2347 NVSGKVQATAQLKVDKKTEVPKFTTNMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGE 2405
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
+ T+ + T+ I T + CE T + K +L V+ V P
Sbjct: 2406 PVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTF 2465
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTI 1347
+ I G ++TL+ P+P W+ + I H K + S L+I
Sbjct: 2466 AKNLEDRLITEG-ELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSI 2524
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN- 1406
+ + D G ++ E+ G A+ ++ ++ K P KP + D + IN+ +
Sbjct: 2525 LQTKLEDKGRITIKAESEFGVAECSASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLEC 2582
Query: 1407 ----TGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460
TG+ T + + + Q + TE + N T I + + + + + A N+
Sbjct: 2583 KLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA- 2641
Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
+ S T KV+ ++ E L + T + ++L + G P+P V+WY +GK
Sbjct: 2642 -GEVS-TEGPLKVVAPIPVE---FETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGK 2696
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYK----CIAFNDHGEVETSCVVGIQQKPVITIS 1576
KL+ ++ + Y C A N++G+ + + + +
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 1577 NEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
E + + + G + + V G P P + WY N ++ N Y I T +KTS + I
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 1636 KRS-HSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVT 1684
H + +A N AG S + Y D S+ E E + +T
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLT 2868
Score = 111 bits (268), Expect = 4e-24
Identities = 145/628 (23%), Positives = 251/628 (39%), Gaps = 53/628 (8%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
Q S + +V G P P ITW K++ + + SD D + P +V D G YT
Sbjct: 561 QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N G A TSA V + E+ A PP F+ + ++ KE I V P P +
Sbjct: 621 CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
W +++ + PS +DG+ +L I + + D+G Y N G A + +
Sbjct: 680 VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738
Query: 924 -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
D +K Q + E +EG+ V + + + + W+ N K +S + + I
Sbjct: 739 ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798
Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031
E G++ C ++ S + V P F + L+D V+EK
Sbjct: 799 EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858
Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088
+ EV+++ + + G+ +K + + ++ I NTS+ HD GE
Sbjct: 859 STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917
Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137
++E TAE +TV + P + +++Q V G A FE + + V
Sbjct: 918 AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977
Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
WF +G ++ Q S +++ KL I AG C VG + A L V
Sbjct: 978 TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035
Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
P + P+F+ + + D + E+ E VTWY K ++ +++ +
Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301
+ I+ +D E V +++ + KL V+ F P+ +++
Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
GS+ P P EW VN + ++
Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVR 1181
Score = 108 bits (260), Expect = 4e-23
Identities = 120/526 (22%), Positives = 205/526 (38%), Gaps = 39/526 (7%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E PP F K + + EG I EC + PEP++ WL + + P + + +
Sbjct: 644 EAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ-- 701
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIV 746
+ L+I + + G YTV N G L ++ + P+ ++ +
Sbjct: 702 --TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVEC 759
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGVYT 804
+GE V + + G+P P I W N KP+ I IL K V +G+ T
Sbjct: 760 DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVT 819
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
+ N G A + V P PP F ++ TV+EK T+ V+ P P++
Sbjct: 820 CQGSNRLGSASCDGRLKVRVP----PAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTL 875
Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
T+ + + E + + + I N + G+ A N G + AR+T+
Sbjct: 876 TFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV 935
Query: 924 DVEK------VTFVKHLQ-KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ E+ TF+K ++ ++ +T E + + W+ N ++ +
Sbjct: 936 EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMD-QGSPGVK 994
Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----KETIPEFIRKLQDFE 1027
E G + C ++ ET LVV ++ P+F+ L D
Sbjct: 995 IEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKT 1054
Query: 1028 VKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
+ + EV + E V W GE +K E G I K+ I+N + D GE
Sbjct: 1055 ETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSI-KISIKNIKIEDAGE 1113
Query: 1087 YSCILRD----ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATF 1126
+ + + A++TV + P PE R + V KG++A F
Sbjct: 1114 IRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVF 1159
Score = 102 bits (244), Expect = 3e-21
Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%)
Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144
+ DES E+ P P+ IT++++ K KG+ A FE + TKG +W KDG
Sbjct: 2867 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2925
Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194
EI+ I++ T G + Q+L + + +DAG+Y+C V G C A LTV E
Sbjct: 2926 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2985
Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246
+ PEFI+ T + +E I + V+W + K++ +++ +
Sbjct: 2986 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 3045
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304
V++ T+ + + Q +YTC+ + + T+K + + V P + + G
Sbjct: 3046 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 3103
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356
+ L + PQP+ ++ S+ K + K T S I+ + + I ++ D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
YK N+ G A +T + +P + + + E + G++ + +
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
+ + + +K +T ++ T + ++ A A N +++S E +
Sbjct: 3223 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 3281
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527
++ PT + L + NE L+ GVP P V W +DG+ ++T AK
Sbjct: 3282 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 3337
Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586
Y C A N GE +T + + V E + + K
Sbjct: 3338 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 3397
Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644
+ ++ + G P P V W+K+ + D + I T + + I + ++ Y+
Sbjct: 3398 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 3457
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688
A N AG + + PE +R + RE T++ K
Sbjct: 3458 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 3502
Score = 97.1 bits (231), Expect = 1e-19
Identities = 113/461 (24%), Positives = 185/461 (40%), Gaps = 44/461 (9%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F + L K + STV FE V G+P P +T+ +K ++ D +
Sbjct: 844 PTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRIS 903
Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + G A+N G A S L VE + S
Sbjct: 904 IPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA------------------ 945
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
PTF K + Q V G + E + P P++ W G ++ D+ S ++ +
Sbjct: 946 -----PTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM--DQG-SPGVKIEA 997
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
H + L I + + GT A N G E +V+ +K+PP+ +E L
Sbjct: 998 HNHDHKLTIDSAQ--YAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTE 1055
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITI-LKPKKVKDEGVYT 804
+V+ +V G P+PT+TW + +K + SI I +K K++D G
Sbjct: 1056 TVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A NSEG ET A +TV++ P F R +TV++ A P+P+
Sbjct: 1116 AVATNSEGSDETKAKLTVQK----KPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTY 1171
Query: 865 TWYRNNEIISPSET---ITQN---FDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917
W N + + +T++ DG +I + T SE++ VA N+ G
Sbjct: 1172 EWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEET 1231
Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
GA++TI+ +K + V Q +E K + + + + +T
Sbjct: 1232 GAQLTIEPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 96.7 bits (230), Expect = 2e-19
Identities = 146/708 (20%), Positives = 276/708 (38%), Gaps = 67/708 (9%)
Query: 1046 DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100
D+ W +D ++ + +++ + ++ G + I V D G Y+C+ +E S +A
Sbjct: 578 DITWYKDDVQLHEDERHTFYSDEDGFFA-MTIDPVQVTDTGRYTCMATNEYGQASTSAFF 636
Query: 1101 TVVEL-----PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL 1154
V+++ PP +T+L++++ +G+ FE E+ + + W D ++ S+ +L
Sbjct: 637 RVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRL 696
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE-EPSINFTLRLPEFILVP 1209
DG+ KL+I D DD G Y+ ++ G+ + A L V+ +P N PEF
Sbjct: 697 QYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVA--PEFQATI 754
Query: 1210 ANTDA-------YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+ + +V D ++ W+ + ++EK IS+ L I+ T
Sbjct: 755 EYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHF 814
Query: 1263 QCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
TC L A +LKV V PP + ++ S V VD +P+P
Sbjct: 815 DGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPT 874
Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
+ + K +K + + S+ ++ D I + +N G A+ +
Sbjct: 875 LTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVA-KAQNEHGTAESRARL 933
Query: 1376 TI-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNI 1433
T+ ++ P L+ I D+ TG + V W I+ +
Sbjct: 934 TVEQEEEESRSAPTFLK----DIE---DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM 986
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEK-PLK- 1489
+ ++ N ++ + + A ++ + +P +K P K
Sbjct: 987 DQGSPGVKIEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKF 1046
Query: 1490 -NITTEPNEDIELTCIFG----GVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX 1540
I + E ++ T +F G P+P VTWY G++LK + ++
Sbjct: 1047 VEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNI 1106
Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGI 1599
+ +A N G ET + +Q+KP + + G E + +A GI
Sbjct: 1107 KIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGI 1166
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--------TIEASNTA 1651
P P W NG K+ + +E T+++++V L ++ Y ++ A NT
Sbjct: 1167 PLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTL 1226
Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
G L + +P K V +++S V E + + E T
Sbjct: 1227 GAEETGAQLTI--EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 90.6 bits (215), Expect = 1e-17
Identities = 86/357 (24%), Positives = 146/357 (40%), Gaps = 16/357 (4%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G PTF+K + + + EG L++ +L + P+P I WL G EI D + + E D
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQ 748
+ S+L+ K +G T+ A + G A L + G P + + + +
Sbjct: 2520 LKLSILQ---TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTE 2576
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-- 806
G+++ + G+P P + W + V A + + + +K V + +K
Sbjct: 2577 GDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCV 2636
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G T + V P P F + T +E T+KL A + P P ++W
Sbjct: 2637 AYNKAGEVSTEGPLKVVAPI-----PVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSW 2691
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--D 924
Y N + + S+ I + + + I ++ + SG C A N GK++ A + +
Sbjct: 2692 YVNGKKLEESQNIKIHSEKGTYTVTIKDITCDY-SGQVVCEAINEYGKATSEATLLVLPR 2750
Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGR 980
E F++ L K V T S WY N KEI D I+ + +
Sbjct: 2751 GEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDK 2807
Score = 88.6 bits (210), Expect = 4e-17
Identities = 75/271 (27%), Positives = 124/271 (45%), Gaps = 20/271 (7%)
Query: 653 LECRLVAI--PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
LEC+L+ P P + W + + E+ ++ + ++ +KI V G
Sbjct: 2580 LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVY----TMKIHGVTADMTGKIKC 2635
Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
VA N+ GE S LK+ P + L R+G+++ L A ++G P P ++W
Sbjct: 2636 VAYNKAGEVSTEGPLKVVA--PIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693
Query: 771 NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
N K ++ + S+ T+++TI K G +A N G A + A + V
Sbjct: 2694 NGKKLEESQNIKIHSEKGTYTVTI-KDITCDYSGQVVCEAINEYGKATSEATLLVLP--- 2749
Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDG 885
EPP F+ + + GT K+V +V T +P PS+TWY NN+ I S+ T D
Sbjct: 2750 -RGEPPDFLEWLSNVRART-GT-KVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDD 2806
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
+ L I + + ++ G+ C A N AG+ S
Sbjct: 2807 KTSTLTINSFNPDVHVGEIICKAENDAGEVS 2837
Score = 86.2 bits (204), Expect = 2e-16
Identities = 151/715 (21%), Positives = 276/715 (38%), Gaps = 68/715 (9%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P F+ KL+D E KE DV E E+ ++VW D + ++P + + + G KL
Sbjct: 648 PAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHD-FRLQYDGQTAKLE 706
Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PEIITRLQNQKVNKGNKAT 1125
IR+ D G Y+ +++E AE+ V P PE ++ + ++G +
Sbjct: 707 IRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVR 766
Query: 1126 FEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179
F+ +T GD + WF +G + S ++ + L I D G +C+
Sbjct: 767 FKSVIT-GDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNR 825
Query: 1180 VGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI---PDETLDVTWYKKKSV 1235
+G++ C L V P T P E V + V++ P+ TL T K+
Sbjct: 826 LGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELK 885
Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE-----F 1286
+ + D R I + E + A+S +L VE E
Sbjct: 886 NGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA 945
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASL 1345
P + D E + +K G + P P W +N K+ + K + L
Sbjct: 946 PTFLKDIE-DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHDHKL 1004
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-----DSSSINIC 1400
TI + AG R EN G + + + +L P +EI ++ +
Sbjct: 1005 TIDSAQY--AGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVV 1062
Query: 1401 WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458
++ E T+ +Y+ + +E+ ++ + ++ + + SI+N+K + RA A N
Sbjct: 1063 FEVRVEGEPKPTVTWYL-KGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATN- 1120
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
S+ S+ T+ K+ + K +P + ++T E + + G+P P W +
Sbjct: 1121 ---SEGSDETKA-KLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVN 1176
Query: 1519 GKKLKT----AKATYENRXXXXXXXXXXXXXXXY--------KCIAFNDHGEVETSCVVG 1566
G+K++ A+ T + Y +A N G ET +
Sbjct: 1177 GRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLT 1236
Query: 1567 IQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I+ +K + + +D+ +V E + ++ P L + K ++T E
Sbjct: 1237 IEPKKESVVVEKQDLSSS-EVQKE--IAQQVKEASPEATTTITMETSLTSTKTTTMSTTE 1293
Query: 1626 KTSVIR--IKELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
TS + E K S S S T+ + G + +++ + SK + +RE
Sbjct: 1294 VTSTVGGVTVETKESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVRE 1348
Score = 70.9 bits (166), Expect = 9e-12
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
+Y E + + + P+PDI W F+G +I S + L IT K
Sbjct: 6419 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 6478
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y A N G+A I++ + T P I+PL + + + + +V G P
Sbjct: 6479 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
P + W K +P+ + DG I+ +D G+Y+ A N G A TS
Sbjct: 6535 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 6594
Query: 820 ITVEEPTEEN 829
+TVE + N
Sbjct: 6595 VTVEAEGDYN 6604
Score = 64.9 bits (151), Expect = 6e-10
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
+++ I+K+ +++ + APIF +LR + FEC V P P++TW
Sbjct: 7504 ERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDF 7563
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
Q I++ S D D+NVA L++ P D G + C A N G S+ LI
Sbjct: 7564 QGKILE-SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI 7616
Score = 60.5 bits (140), Expect = 1e-08
Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531
K+++ ++P L++ TT+ +E + L C G P+PKV+W D K + T E+
Sbjct: 2987 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 3046
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589
Y CIA N G +T + +Q + PV T ++++ K +G++
Sbjct: 3047 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 3103
Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641
+++ ++G P P V +Y K K+ + I + + R I ++ +
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y A+N+ G TS+ ++T KV + P +G +E + +E K +E
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
K E N+ K + + V T +++ + A NP G +E+
Sbjct: 3223 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 3273
Score = 57.6 bits (133), Expect = 9e-08
Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 3/149 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+Q P FVE L K +TV FE +VEG P+P +TW+ + +K S ++ D
Sbjct: 1038 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 1097
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXX 622
++ + I+ + EDAG VA N+ G + +L V+ P + V
Sbjct: 1098 SI-KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSE 1156
Query: 623 XXXADILEGIP-PTFSKKPKAQYVDEGSD 650
+ GIP PT+ + V +G +
Sbjct: 1157 AVFSAHAFGIPLPTYEWSVNGRKVRDGQE 1185
Score = 57.6 bits (133), Expect = 9e-08
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565
S+ P F +KLRP + T+ + V G P P + WF+ I D+
Sbjct: 3479 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGH 3538
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608
TL I++ ED G +TC A N AG A +T + V EAPL G
Sbjct: 3539 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 3585
Score = 57.2 bits (132), Expect = 1e-07
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 9/171 (5%)
Query: 1507 GVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P +TWY+D +L T + + Y C+A N++G+ T
Sbjct: 573 GYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQAST 632
Query: 1562 SC---VVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
S V+ ++++ ++ K K GD +EG P PE++W + L
Sbjct: 633 SAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSH 692
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
++ + +T+ + I++ + + YT++ N G+ + L V P K
Sbjct: 693 DFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDK 743
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
++P + +PL+NI + L C F G P+P + W++DG+++ + +
Sbjct: 5813 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5872
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581
Y+C+A N +G TSC V + +KP I S + K
Sbjct: 5873 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5932
Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639
++ K GD + G P P + W K+G +L +D++ + + T + + ++
Sbjct: 5933 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5992
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ A+N GT+S + L +
Sbjct: 5993 EGYFRCVATNEHGTASTKAELVI 6015
Score = 55.6 bits (128), Expect = 4e-07
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
D YT +Q + K +F + ++ +AP F + +G V+F+ + G
Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773
Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
P P+I WF + S+ + + +D + L I++V G TC N G AS
Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832
Query: 596 TELIVEAP 603
L V P
Sbjct: 833 GRLKVRVP 840
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
++P PL +P + + C+ G P P + W +DG +L + +A +
Sbjct: 5923 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5982
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
++C+A N+HG T +G + P + E+ K + +
Sbjct: 5983 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 6042
Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
G E V +I GIP P V WYK+G ++ D K T + + I
Sbjct: 6043 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 6102
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+Y++EA+N G++ E +L +
Sbjct: 6103 NASPDDEGEYSLEATNKLGSAKTEGSLNI 6131
Score = 53.6 bits (123), Expect = 1e-06
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
+ +++ + V G P P I W + P + G + + + ++ G
Sbjct: 6423 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 6482
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
Y A+N G A+ + I V+ T N PL +N+ T +++ RV P
Sbjct: 6483 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 6535
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
P + W + I S I DG + +I N DSG Y CVA N AG+++ V
Sbjct: 6536 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 6595
Query: 922 TIDVE 926
T++ E
Sbjct: 6596 TVEAE 6600
Score = 53.2 bits (122), Expect = 2e-06
Identities = 26/93 (27%), Positives = 49/93 (52%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
I + D+G ++CVA N AG A+++ + VEA
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 6599
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559
Q AP+F ++L+ K G + C V+G P+P + + F +T ++ S +
Sbjct: 3083 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 3142
Query: 560 YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612
+D N +VI ++ ED ++ +A N+ G A+ST+++ VEAP+ + G + T
Sbjct: 3143 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 3198
Score = 51.6 bits (118), Expect = 6e-06
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
L V E + + AP F+ L+ K T V EC+V G P+P+++W I +Q
Sbjct: 2979 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 3036
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604
+ + V + I G +TC+A+N G + + L V EAP+
Sbjct: 3037 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 3088
Score = 50.0 bits (114), Expect = 2e-05
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
S+ + +V GYP P ITW++ + + Y D+D + I V D G +TC+
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 585 AKNAAGFASST 595
A N G AS++
Sbjct: 623 ATNEYGQASTS 633
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/235 (20%), Positives = 88/235 (37%), Gaps = 12/235 (5%)
Query: 1466 ETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
ET KV++ K + P L+++ + +++ I + P WY++G L+
Sbjct: 1965 ETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLED 2022
Query: 1525 AK--ATYENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNE 1578
K T +N + A N+ G E+S + + P++ +
Sbjct: 2023 GKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPK 2082
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ K E+ T I G P P V W N +E + E ++I K
Sbjct: 2083 SVTIKETETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIE 2140
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692
+ + A N+AG S + LKV P+ + +++ E + W LD
Sbjct: 2141 QTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 2195
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAE---PPLFINRFQEITVKE 846
L+PK + KA ++ I A I P T++N + P+F R +++ +++
Sbjct: 7482 LEPKSHEQSTALLQKAPSATAIERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRK 7541
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
V+ +P P +TW +I+ ++ +T D N+ +I N + D G+Y C
Sbjct: 7542 NQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQD-NNVARLILNHAAPYDLGEYVC 7600
Query: 907 VASNSAGKSSHGARV 921
A N G R+
Sbjct: 7601 TAINEYGTDKSSCRL 7615
Score = 48.8 bits (111), Expect = 4e-05
Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 8/169 (4%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ P P+V W G LE++ I + + + +Y A N GT
Sbjct: 7551 VSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDK 7610
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNN--- 1711
L + PS+P P E+S ++ + I+W+ P LE Y +E N
Sbjct: 7611 SSCRLISGETPSRPGRP--EAELSSDTEIFIQWEAPEGPTYLEGITYRLEYRVAGPNDHG 7668
Query: 1712 -RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
WI V++ D E+ ++ L+ Y FRV AQN G S IV
Sbjct: 7669 DPWITVSE-KIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIV 7716
Score = 48.0 bits (109), Expect = 7e-05
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
+E P R L + + E +V + V T V W +DG+ I P + F
Sbjct: 6034 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 6093
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
I L I N S DEGEYS ++ +A+ + ++ PP +
Sbjct: 6094 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 6153
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
+L+N+ V F+ + A V WF +G +I I++ + G L I D
Sbjct: 6154 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 6213
Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
L+DAGEY G++ +A+L V P ++ E + P T+ Y
Sbjct: 6214 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 6264
Score = 47.2 bits (107), Expect = 1e-04
Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 5/177 (2%)
Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
F P R+ +++ A P P W KI++ D+ A L
Sbjct: 7526 FAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARL 7585
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
+ D G Y N G + + PS PG+P + I I W+ PE
Sbjct: 7586 ILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPE 7645
Query: 1406 NTGNSTIIYYVVEYQEIDTTE----WISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
I Y +EY+ + WI+V + I +++L Y+FR A N
Sbjct: 7646 GPTYLEGITYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQN 7702
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437
P+PP + P I E+ + + W + + YV+E +E+ +W ++ NI +
Sbjct: 6275 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 6334
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
++NL+ SY+FR A N ISD S
Sbjct: 6335 CKVRNLELGKSYQFRVRAENIYGISDPS 6362
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ + + Y+ + + EC + A P P + W F+G+ + + N V IE D ++ +
Sbjct: 7528 PIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGK--ILESNDRVTIEQDNNV--A 7583
Query: 694 VLKITNVKKFQEGTYTVVAVNREG 717
L + + + G Y A+N G
Sbjct: 7584 RLILNHAAPYDLGEYVCTAINEYG 7607
Score = 39.9 bits (89), Expect = 0.019
Identities = 45/203 (22%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXX 1534
P + + L N++ +E+ G+P P V WY+DG+++ K T E
Sbjct: 6038 PRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIH 6097
Query: 1535 XXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE------------DIK 1581
Y A N G +T + I + I ++E +K
Sbjct: 6098 HLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 6157
Query: 1582 QKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSH 1639
KH + ++ G P PEV W+ NG K+ I + S + I +
Sbjct: 6158 NKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLED 6217
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ +Y A N+ G++S L V
Sbjct: 6218 AGEYVATAKNSHGSASSSAVLDV 6240
Score = 39.1 bits (87), Expect = 0.034
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++
Sbjct: 6402 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 6461
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
Y + TL I E+ G + C AKN G A
Sbjct: 6462 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 6495
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472
E R A+ Y + + EAI L +G+ + +LD N W V+ K GWVP
Sbjct: 61 ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120
Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500
Y + Y Q++ +I+ + + ++
Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
+ G P P++ WYK+ +L D+ + + E + I ++ + + +YT A+N G +
Sbjct: 571 VTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQA 630
Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678
S +V + P + ++
Sbjct: 631 STSAFFRVLKVEKEAAPPAFVTKL 654
Score = 35.9 bits (79), Expect = 0.32
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 11/130 (8%)
Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDD----KITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
L + + I EI + PY +++ K+ TPP R + E T +TL
Sbjct: 6238 LDVTVPFLDSIKFNGEIDVT-PYLTEEYGFKKLNTASLPTPPD--RGPFIKEVTGHYLTL 6294
Query: 1885 KWTEPE-SNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA 1942
W + + P Y+IE + + K W+ + + V + + N++ FR+ A
Sbjct: 6295 SWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCK--VRNLELGKSYQFRVRA 6352
Query: 1943 ENTVGVSLPT 1952
EN G+S P+
Sbjct: 6353 ENIYGISDPS 6362
Score = 35.5 bits (78), Expect = 0.42
Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 4/87 (4%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYE---NRXXXX 1536
+P L+++ N+ C P PKVTW GK L++ + T E N
Sbjct: 7527 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 7586
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSC 1563
Y C A N++G ++SC
Sbjct: 7587 LNHAAPYDLGEYVCTAINEYGTDKSSC 7613
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1786 ITWFPSEKNGGS-PIIDYKVEIKQ-EGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYAR 1842
++W P+++ P + Y +EI++ K+W +++ L + +YQFR+ A
Sbjct: 6294 LSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAE 6353
Query: 1843 NEIGTSLP 1850
N G S P
Sbjct: 6354 NIYGISDP 6361
Score = 31.9 bits (69), Expect = 5.2
Identities = 35/193 (18%), Positives = 66/193 (34%), Gaps = 5/193 (2%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYC 692
P F +P + V++GS+ + IP P W G ++ E V +
Sbjct: 1140 PEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGA 1199
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S+L I + E + ++V E T E + V+ + + + +
Sbjct: 1200 SILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKESVVVEKQDLSSSEVQKE 1259
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYTLKAE 808
I +P T T T + T+ ++ K+ + E T+
Sbjct: 1260 IAQQVKEASPEATTTITMETSLTSTKTTTMSTTEVTSTVGGVTVETKESESESATTVIGG 1319
Query: 809 NSEGIAETSAVIT 821
S G+ E S ++
Sbjct: 1320 GSGGVTEGSISVS 1332
Score = 31.5 bits (68), Expect = 6.8
Identities = 48/230 (20%), Positives = 83/230 (36%), Gaps = 16/230 (6%)
Query: 180 EAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLT-----PIK 234
E ++ ESE+ ++TS + PEK+ D+K S T + +T P+K
Sbjct: 1508 ETTMTTEMTHESEE--SRTSVKKEKTPEKV---DEKPKSPTKKDKSPEKSITEEIKSPVK 1562
Query: 235 IERKEMEVSTPQHAETVD--GPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSW 292
E+ +V + T P+ T K P+ + +K
Sbjct: 1563 KEKSPEKVEEKPASPTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPKEK 1622
Query: 293 PPESI--KPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYED 350
PE KP + ++K K +K + P + P +D
Sbjct: 1623 SPEKADDKPKSPTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDD 1682
Query: 351 IVES--KKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDE 398
V+S KK+++ E++ KE PE+ + KS +K E +E
Sbjct: 1683 EVKSPTKKEKSPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEE 1732
Score = 31.1 bits (67), Expect = 9.0
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 15/123 (12%)
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
A NE GT S ++ G+T + P +P + S++ + ++W PE Y
Sbjct: 7602 AINEYGTD---KSSCRLISGETPSRPGRPEAELSSDT---EIFIQWEAPEGPTYLEGITY 7655
Query: 1901 IIEFKTV----KGKSWTKIVTVGGSVHEHCI--ENIKEKDEIIFRISAENTVGVSLPTES 1954
+E++ G W +TV + + + +++ FR++A+N G+ LP+ S
Sbjct: 7656 RLEYRVAGPNDHGDPW---ITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLS 7712
Query: 1955 QSV 1957
+
Sbjct: 7713 SRI 7715
>U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein.
Length = 6632
Score = 261 bits (640), Expect = 3e-69
Identities = 304/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%)
Query: 460 KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506
+H+ E+KG + L+ D NN YT K +E + +L + FEK T+EE
Sbjct: 3625 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3683
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
+ P+F+E L+ +G TV EC+V PQI +F+ ++ Q Q+ +D
Sbjct: 3684 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3742
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620
L I+ ED G + C A N AG A++ +L VE ++D ++
Sbjct: 3743 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3802
Query: 621 XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ G P F + ++ V E +L+C++ P P I W +G+E+
Sbjct: 3803 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3862
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734
+ + D + L NV + + A N G A PI++ ++ K E
Sbjct: 3863 VRAEHKDDGTL---TLTFDNVTQARRRRIRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3919
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790
P ++P+K ++V GE+ +L ++ G P+P++ W KN KP + ++ D T +T
Sbjct: 3920 PDFLQPVKPVVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3979
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+ K+ D Y +A N G + +TV+EP + P F I VKE T
Sbjct: 3980 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 4035
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
K +V+ P + W+++ + + + ++ D LVI + ++ D G+Y+ S
Sbjct: 4036 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 4093
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968
N AG ++ +T+ + +K +G ++L + T KWY + ++
Sbjct: 4094 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 4153
Query: 969 GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018
+I+Q D G + ++ + ++T+ V K ++P
Sbjct: 4154 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 4213
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077
F + L D V + +LEVEI + DV W ++G+ IK K E G+ + +L I
Sbjct: 4214 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 4269
Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ D GEYS +E+ E V PEI++ L V +G ATF +++
Sbjct: 4270 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190
V+W+K+G EI + + DG L+I + ++DA +Y S + G++ +A LT
Sbjct: 4330 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 4387
Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
V+ PE + L+P A V++ V WYK I + +
Sbjct: 4388 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 4445
Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302
+ +L I DD +Y V+ DA V+ P IV + + +G
Sbjct: 4446 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 4505
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361
L V+ P+ +W N K I +P D L I + DA YK+
Sbjct: 4506 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416
L + G+ AD +T+ P +P I++ ++ ++I E E +G+ + +
Sbjct: 4565 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 4621
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+E+ ++K I K + L+ SS ++A K+ E
Sbjct: 4622 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4680
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531
KI T KPLK+ + E+ E + P+ V WY++G+++K + +
Sbjct: 4681 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4736
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587
+ YK + N GE E+S + +++ I ED Q G
Sbjct: 4737 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4794
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+ + I+G P +V W ++ N + I + T+ + I + +YT+E
Sbjct: 4795 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4853
Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671
N +G + + +V +KP G
Sbjct: 4854 VINESGKAKSDAKGEVDEKPEIVRG 4878
Score = 246 bits (602), Expect = 1e-64
Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G+ ILL + P+ + W +KG E V + ++ Y L+I + +
Sbjct: 4124 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 4179
Query: 705 EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y VV + + S V K EK P + L V +G ++L ++ G P
Sbjct: 4180 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 4239
Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+ + W KN +K + G+ + + KD G Y++ A N G E+ A + V
Sbjct: 4240 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 4298
Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+A+P + ++ TVK+ T +V + PV + WY+N + I ++T N
Sbjct: 4299 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 4349
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935
DG + L I N E D+ DYK V SN AG + A +T+ D K V L
Sbjct: 4350 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 4407
Query: 936 KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
+ ++G+T + V KWY N KEI ++ D
Sbjct: 4408 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 4464
Query: 995 GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
K +V D ++S L VK ++ L+D EV + A+L+VE N + ++ W
Sbjct: 4465 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 4524
Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103
++G+ I P + +L I + D EY +L DE SC V +
Sbjct: 4525 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 4584
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160
P+II L++Q V+ G+ EIE + V+W+K+G E+ + I++ ID K
Sbjct: 4585 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4644
Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
L+I ++D G+Y EV G++ + +TVE P I F L + + +A
Sbjct: 4645 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4702
Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271
+VE + V WYK I+ +F + K L+I+ DD Y VL
Sbjct: 4703 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4762
Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+A+S+ +L V+ + KIV + + +G+ + V Q P+ + W+ ++ +I
Sbjct: 4763 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4821
Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
+ ID + L I + DAG Y + + N G A + + +KP
Sbjct: 4822 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4881
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447
+EI ++ + E + + + QEI + K I K + +I + +
Sbjct: 4882 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4939
Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
++ N D+S V+K ++ + LK++ E + +EL G
Sbjct: 4940 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4993
Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
+P+ + WY++G++LK ++ Y+ + ND GEV
Sbjct: 4994 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 5052
Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
+ VV ++ K S + K GD + I G P PEVIW K+G L+
Sbjct: 5053 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 5112
Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670
D + + T+ +RI+ K+S +Y + A N AG TS +VT+ + ++PSKP+
Sbjct: 5113 KDDRITMRVALDGTATLRIRSPKKSDIGQYRVSAKNEAGSATSDCKVTVTEQGEQPSKPK 5172
Score = 243 bits (595), Expect = 1e-63
Identities = 293/1183 (24%), Positives = 487/1183 (41%), Gaps = 110/1183 (9%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G+ + +VEG P+ + W++ T + SQ ++ ++ L I D G +
Sbjct: 4127 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 4185
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
V ST VE+ + +TV P+F K Q
Sbjct: 4186 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 4221
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V +G+ ++LE + P+ D+ W G+EI D + D+ L I + ++
Sbjct: 4222 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 4274
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y+V A N GE I K K P+++ L V+QGE+ + +V G P
Sbjct: 4275 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 4329
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
+ W KN K + TK +GD + +V+D Y + N G A++SA +TV+
Sbjct: 4330 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 4389
Query: 824 EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
+ ++ P ++ TVK+ T +V + PV + WY+N + I P+ N
Sbjct: 4390 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 4447
Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
DG + L I N + D+ DYK V SN AG + A +T+ + + VK L+ + E +
Sbjct: 4448 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 4504
Query: 943 GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000
GK +L+ +T+ KWY N KEI+ D + +G D K +
Sbjct: 4505 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564
Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
+ D++ +T L VK P+ I+ L+D V LE+E + V W ++G
Sbjct: 4565 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 4624
Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109
+ + K ++ K L I ++ V D G+Y + +E+ +A + + + P+I
Sbjct: 4625 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4684
Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166
+ L++Q + +G A F +E +V+W+K+G EI+ ++ I+ D K Q L I
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4743
Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220
+ DDA Y + G ++ +A LTV++ ++ E +V V+I
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4803
Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
E DV W + +VI + I D R LII D EYT +++ K+
Sbjct: 4804 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4862
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
+ K EV E P+IV I G D V+ A P +W N + IK H +
Sbjct: 4863 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4920
Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I K L I + + D YK+ L N G D +T++ KPN+L+I
Sbjct: 4921 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4973
Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
++ +EP+ G +I + QE+ + K K ++ +L SS
Sbjct: 4974 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 5032
Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503
+ A V +D E V +K K PT PLK+ E + + L C
Sbjct: 5033 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 5092
Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
G P P+V W +DG L+ T + + Y+ A N+ G
Sbjct: 5093 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSPKKSDIGQYRVSAKNEAGS 5152
Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611
+ C V + + KP I +K + D+ + G+P P W+ NG
Sbjct: 5153 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPADKKEFNVKVRGLPNPTFQWFLNGI 5209
Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
++ D + + + I++++ A N GT
Sbjct: 5210 PIKLDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 5252
Score = 217 bits (531), Expect = 5e-56
Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+E L G+ V + G P+P +TW+ I S D DD +TL
Sbjct: 2754 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2812
Query: 570 IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626
I P+ G C A+N AG S T +I S+ SE +
Sbjct: 2813 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2872
Query: 627 --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ + P P F K K +G + EC + WL G+EI
Sbjct: 2873 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2932
Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733
I V + + + L + NV G YT + N G EA+L ++ + K EK+
Sbjct: 2933 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2992
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791
P+ I L+ + E V+L +V+G P+P ++W +NK + +++ +S +TI
Sbjct: 2993 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 3052
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849
++ +G YT AEN+EG ++T A +TV+ E P+F Q E+++ EK
Sbjct: 3053 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 3103
Query: 850 IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901
+ L V +P P + +Y +E I+ S I D N +VI+ + E D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 3162
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960
YK +A+NS G ++ +++T VE F + L+K+ +E + + +E + + +W
Sbjct: 3163 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 3221
Query: 961 YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014
+ + K +S + E+ + E D G + E+S V +
Sbjct: 3222 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 3281
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070
++ P F+R+L EVK + A L V + V W +DG+ ++ + + G
Sbjct: 3282 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 3341
Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124
+ I++ + D G+Y+C + E+ T A VV+ +PPE + +L +V +
Sbjct: 3342 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 3401
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
T +++ + V WFKD + I N H IQ L I D D G YSC
Sbjct: 3402 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 3461
Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232
E G + TA + SI FT +L P + D +TV I +V W+K K
Sbjct: 3462 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 3520
Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
I+++ F TL I++ +D YTC +AK+T + V+ P
Sbjct: 3521 PINIDNSHIFGKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 3580
Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346
V + Y +++G L+V + P+P +W + I +H + ++ S +L
Sbjct: 3581 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3640
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
IK N D G Y + N G
Sbjct: 3641 IKDTNNADFGKYTCQATNKAG 3661
Score = 211 bits (515), Expect = 5e-54
Identities = 292/1248 (23%), Positives = 487/1248 (39%), Gaps = 138/1248 (11%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+E+ AP+FV+ L+P G + +VEG P P++ WF+ I + +
Sbjct: 3574 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 3633
Query: 564 NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
N + TLVI++ D G +TC A N AG E + E + + E
Sbjct: 3634 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3681
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
E + P F + K + EG ++LEC++ P I + + + +++ +
Sbjct: 3682 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3734
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
+ D ++ L I N KK G Y AVN G+A+ LKI+ K V +
Sbjct: 3735 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3791
Query: 743 SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781
+ + Q E+V +L + V + I CK +P +
Sbjct: 3792 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3851
Query: 782 SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824
+G ++ + KD+G TL +AEN G A T ++T+E
Sbjct: 3852 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQARRRRIRCEAENEYGSAWTEGPIIVTLEG 3911
Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883
+ + E P F+ + + V T L +++ P PS+ WY+N E + PS+ + +N
Sbjct: 3912 APKIDGEAPDFLQPVKPVVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3971
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940
D L +TN + D +Y+C ASN G +T+ + +V F K L + +
Sbjct: 3972 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 4029
Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
+E +T EC+ S T KW+ + + H E +G D G
Sbjct: 4030 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 4088
Query: 998 KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052
+ + D + V +P K L D V + +L VE+ + V W +
Sbjct: 4089 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 4148
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106
E + + + KL I + + D G Y +L +S + E VTV +
Sbjct: 4149 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 4208
Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P L +Q V KG E+E+ V+W+K+G EI+ ++ + K +L
Sbjct: 4209 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 4266
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217
I D D GEYS N A + +N + + PE + LVP A
Sbjct: 4267 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 4322
Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273
V++ V WYK I D + T + +L I +D +Y V+ DA
Sbjct: 4323 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 4380
Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
S+ L V++ + P+IV +K+G T V + P +W N K I
Sbjct: 4381 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 4439
Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
K K + D S SL I + D YK+ + N+ G AD +T+ PG
Sbjct: 4440 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 4493
Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443
+ ++ + + + E I + +EI ++ K Q I +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 4553
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+ + ++ +E D + + + + P + K L++ I+L
Sbjct: 4554 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 4609
Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
G P+ V WY++GK+L A A +N+ YK N+
Sbjct: 4610 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4668
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G +S + ++ P IT + +K + E +V P V WYKNG +++ +
Sbjct: 4669 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4725
Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
+ I K T + IK R + Y I NTAG SS ++T+K
Sbjct: 4726 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4773
Score = 198 bits (483), Expect = 4e-50
Identities = 264/1127 (23%), Positives = 448/1127 (39%), Gaps = 106/1127 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V +G +L+ P+ +I W G+EI P + + D L I +
Sbjct: 4502 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 4557
Query: 705 EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
Y VV + +G A L +K KEP ++I+ L+ +V G + L + G+P+
Sbjct: 4558 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 4616
Query: 764 PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
T+ W KN K + K + + D + + V+D G Y ++ N G A +S
Sbjct: 4617 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4675
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876
ITVE P +P + Q IT E V N P I WY+N + I P S
Sbjct: 4676 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4726
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
I + +LVI N + D+ YK V N+AG++ A++T+ K K + K
Sbjct: 4727 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4784
Query: 937 SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991
E + +G ++ E + +W + IS + I + +
Sbjct: 4785 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4844
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D G V ++ K + PE +R L++ E+ E D + +VE+++ V
Sbjct: 4845 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4904
Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105
W ++ + IKP + + +K G + +L I + D +Y +L + + C + + +
Sbjct: 4905 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963
Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159
P +I+ L++ V + ++++ +++W+K+G E++ + +
Sbjct: 4964 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 5023
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214
+ L I D G Y +GN K +++ V+ + F+ +T+
Sbjct: 5024 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 5083
Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267
LT++ I E +V W K V++ ++ T+ ++ TL IR + D +Y
Sbjct: 5084 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSPKKSDIGQYR 5143
Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ +T+ KV V E PK V + V + P P +
Sbjct: 5144 VSAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPADKKEFNVKVRGLPNPTFQ 5203
Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
W +N IK + T + + LTI+ V D G K +N G D +
Sbjct: 5204 WFLNGIPIKLDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 5262
Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437
G + L WD G+ I V+ EW K I T
Sbjct: 5263 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 5322
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480
T I+N + + R + E DI +ET Y+V ++E K +
Sbjct: 5323 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 5381
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535
+P + PL++ T + I L+C +P+ V WY+DG L+ T YE
Sbjct: 5382 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 5441
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587
Y+C+A N HG + TSC V ++ ++ V E K V G
Sbjct: 5442 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 5501
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646
D + + + G P PE+ WY+NG L N I T+ + + + + E S Y E
Sbjct: 5502 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685
A N T T+ V++ L +KP EG P + E+S SV++
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 5608
Score = 180 bits (439), Expect = 8e-45
Identities = 143/525 (27%), Positives = 224/525 (42%), Gaps = 45/525 (8%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+++ P FV KLR K +G + FEC+VEG+P P++ W ++PS DF++ YD
Sbjct: 642 EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622
A L IR+ P+D G +T +N G S EL V+A P +H
Sbjct: 702 T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
+ P F + DEG ++ + + P P+I W G+ + E +
Sbjct: 746 ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
E + C +L I +V + +G T NR G AS LK++ PP +PL+
Sbjct: 797 ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798
V++ +V+ V G P PT+T+ K +K + + I+I K
Sbjct: 852 DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
+G KA+N G AE+ A +TVE+ EE+ P F+ ++ TVK V
Sbjct: 912 HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
NP P +TW+ N + + + N + +T +DS +G C A N+ G+
Sbjct: 972 NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029
Query: 919 AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
AR V + EK FV+ L ET + TV+ E + + WY +E+ D
Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088
Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
EI + D G I+ + + E S K T+
Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTV 1133
Score = 176 bits (429), Expect = 1e-43
Identities = 287/1251 (22%), Positives = 486/1251 (38%), Gaps = 155/1251 (12%)
Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
V+ L P G + + P+ +I W++ I PS Q D DN LVI +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 4552
Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
+DA + V + G + D +TV L
Sbjct: 4553 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 4586
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691
P K + Q V GS I LE P+ + W G+E+ ++ I+ D + Y
Sbjct: 4587 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4645
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750
VL+I + G Y V N G A+ + + EP ++PLK + +GE
Sbjct: 4646 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4698
Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
+ S + PR + W KN KP + DT ++K D Y +
Sbjct: 4699 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4757
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866
EN+ G AE+SA +TV++ + I + E V KG K+V V P + W
Sbjct: 4758 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4812
Query: 867 YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
R+ +IS + I + D L+I + D + D+G+Y N +GK+ A+ +D
Sbjct: 4813 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4870
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984
EK V+ L+ + E EG + + + S V KWY N +EI H E + G
Sbjct: 4871 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4929
Query: 985 XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
D G V+ D ++S L VVK + + + L+D +V+E L+V
Sbjct: 4930 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4989
Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095
++ + W ++G+ +KP + + FE++ + L I ++ D G Y +L D+
Sbjct: 4990 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 5049
Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143
+VV + ++ L++ +V +G+ T + + G+ V W KDG
Sbjct: 5050 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 5108
Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193
+Q + I ++ +DG L+I D G+Y N S C +T E+
Sbjct: 5109 VVLQKDDRITMRVALDGTAT-LRIRSPKKSDIGQYRVSAKNEAGSATSDCKVTVTEQGEQ 5167
Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244
PS F + L +PA+ + + V +P+ T W+ I+ ++ TL
Sbjct: 5168 PSKPKFVIPLKTGAALPADKKEFNVKVRGLPNPTFQ--WFLNGIPIKLDDRITLDDMADG 5225
Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
I DV++ KC E+ E C + + +PP+ +
Sbjct: 5226 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 5285
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354
RI G + + A P EW + K I+ HT + ++D + + I E +D
Sbjct: 5286 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 5344
Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
G+Y N G A+ + V IL+ + + + D+ N G
Sbjct: 5345 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 5401
Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458
+ V+ + W + ++TSIQ L N S +R A N
Sbjct: 5402 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 5461
Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
+ S + +E K + P K L ++ + + L C G P P++ WY
Sbjct: 5462 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 5521
Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
R+G+ L+ T + Y+C A N HG+ +T +Q
Sbjct: 5522 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 5581
Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+KP ++ +S+ + + + E VT G+P P V W K+G L
Sbjct: 5582 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 5637
Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
D + + + V +RIK Y A+N G+++ + +++ D
Sbjct: 5638 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5688
Score = 170 bits (414), Expect = 8e-42
Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%)
Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563
MAP F+ K++ G + FEC V W + I+ ++ +
Sbjct: 2885 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2944
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
LV+ V PEDAG +TC+ +N AG + L V L +
Sbjct: 2945 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2993
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
P F + + ++LEC+++ P+P ++WL + I + S+
Sbjct: 2994 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 3040
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
+ES + + IT+ + +G YT +A N EG + L T + E P + L++
Sbjct: 3041 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 3095
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792
+ GE ++LS V G+P+P + + ++ K + TK +TH ++
Sbjct: 3096 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 3154
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
+D Y A NS G A +++ IT + E P+F ++ +VKEK IK+
Sbjct: 3155 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 3208
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911
+V P + W+++++ +S + E + ++ + D+G Y ASN
Sbjct: 3209 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 3267
Query: 912 AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
AG +SS A VT +EK TFV+ L + E T+ + + S +W + + +
Sbjct: 3268 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 3327
Query: 969 GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020
I ++ D G C + + + VVK + PEF+
Sbjct: 3328 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 3387
Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077
KL EVKEK+ L V+ + + V W +D I N + +K+ + L I
Sbjct: 3388 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 3446
Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131
+ D G YSC R+E+ TA ++ +PPE +L+ +V + + T ++++T
Sbjct: 3447 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 3504
Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182
G + V WFKD I N HI +G L I +D G Y+C E G
Sbjct: 3505 VIGTPVPNVEWFKDDKPINIDNSHIFGKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 3564
Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237
+K TA + V+E + F L + V A L V + + +V W+K I+
Sbjct: 3565 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 3623
Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286
+ + TL+I+ D +YTC + K T +LK+ F
Sbjct: 3624 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3683
Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344
P ++ +E G V L P ++ N + ++ +H + + + +
Sbjct: 3684 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3743
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
LTI+ + D G Y+ N G A+ ++ I
Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 165 bits (402), Expect = 2e-40
Identities = 207/921 (22%), Positives = 380/921 (41%), Gaps = 86/921 (9%)
Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
+L V E P +++ P F +KLR G TVQ + V P W++ +++
Sbjct: 1969 ELKVLETP---KETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGNLLEDG 2023
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
++ +++N ++L+I +D+G T A N G S+ +++TV
Sbjct: 2024 KNGVTIKNEENKSSLIIPNA--QDSGKITVEASNEVGS-------------SESSAQLTV 2068
Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
+++G PK+ + E + + P P + W E+
Sbjct: 2069 NPPSTTPI------VVDG--------PKSVTIKETETAEFKATISGFPAPTVKWTIN-EK 2113
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
IV + I+++ +Y LKI+N K Q GT V A N G+ S LK++ K
Sbjct: 2114 IVEESRTITTIKTE-DVY--TLKISNPKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKA 2170
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVG-NPRPTITWCKNNKPVKALPTKS---DGD-THS 788
P + L + +GE + + ++ G +P ++W N +P+ T GD T+
Sbjct: 2171 P-KFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYH 2229
Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
+TI + K + G T K +N+ G ETS +TV ++ P F+ Q +G
Sbjct: 2230 VTIAEAKP-EMSGTLTPKPKNAAGECETSPKVTVNGGNKK----PEFVQAPQNHETTLEG 2284
Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID-SGDYKCV 907
++K A VT P+P++TWY NN+ + SE + + E + I ++ +G +
Sbjct: 2285 SVKFSAIVTGKPIPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVE 2344
Query: 908 ASNSAGKSSHGARVTID--VEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHN 963
A N +GK A++ +D E F ++ + +EG+ V S W N
Sbjct: 2345 AENVSGKVQATAQLKVDKKTEVPKFTTNMD-DRQVKEGEDVKFTANVEGYPEPSVAWTLN 2403
Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC----IVKDQETSTMLVVKET--IP 1017
+ +S + + + G + C V ++ L VK+ P
Sbjct: 2404 GEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAP 2463
Query: 1018 EFIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDG-EIIKPKKNKYDFEKRGHIRKL 1074
F + L+D + E ++ +++ ++N + W +DG EI K E+ G + KL
Sbjct: 2464 TFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSL-KL 2522
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQ--KVNKGNKATFEI 1128
I T + D+G + E C+A + VV+ P Q+ +N T E
Sbjct: 2523 SILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLEC 2582
Query: 1129 E-LTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
+ L GD V+W+ + + +++ +KI+ D G+ C + G
Sbjct: 2583 KLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKAG 2642
Query: 1182 NSKCTAILTVEEP-SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
L V P + F L + +T V + + V+WY +E+++
Sbjct: 2643 EVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKKLEESQ 2702
Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVE--FPPKIVDYERE 1296
+ S+ T+ I+ T D + C ++ K+T++ + V+ PP +++
Sbjct: 2703 NIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDFLEWLSN 2762
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
R + G+ V V + P+P+ W +N+K I D K+++LTI N D
Sbjct: 2763 VRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF-NPDVH 2821
Query: 1357 IYKL--RLENNCGHADVEMNV 1375
+ ++ + EN+ G N+
Sbjct: 2822 VGEIICKAENDAGEVSCTANM 2842
Score = 164 bits (398), Expect = 7e-40
Identities = 253/1135 (22%), Positives = 431/1135 (37%), Gaps = 126/1135 (11%)
Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
TF K K Q + EG + P + W G+EI P+ + ++D Y V
Sbjct: 4684 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4741
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
+K N + TY +V N GEA L +K + ++++ L+ +V +G ++
Sbjct: 4742 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4799
Query: 755 SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
++ G P + W ++ + A + K D T+ + I+ +KD G YT++ N
Sbjct: 4800 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4857
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
G A++ A V+E E + + I + E V+ PV + WY+N+
Sbjct: 4858 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4909
Query: 871 EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
+ I P+ + G + EL I + D DYK V SN+AG A +T+ V
Sbjct: 4910 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4968
Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984
+ K + EE + V L+ + KWY N +E+ G E + G
Sbjct: 4969 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 5028
Query: 985 XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033
D G + ++ K + S +V K + P F+ L+D EV+E D+
Sbjct: 5029 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 5087
Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
L+ I E +V+WE+DG +++ L IR+ D G+Y +
Sbjct: 5088 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSPKKSDIGQYRVSAK 5147
Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142
+E+ +A +VTV E P+ + L+ +K F +++ + +WF +
Sbjct: 5148 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPADKKEFNVKVRGLPNPTFQWFLN 5207
Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193
G I+ + I L DG L I D +D G C N T E +
Sbjct: 5208 GIPIKLDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 5266
Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244
LR P VP D + V P + T +V W+K IE T +
Sbjct: 5267 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 5325
Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290
+ V I I E D Y CV ++ A++ +VE++E + PKI
Sbjct: 5326 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 5385
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349
+ + G + L A P+ + W + ++ T + +A+L I
Sbjct: 5386 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 5445
Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
D G Y+ N G + +V + K + + W + G+
Sbjct: 5446 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 5502
Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455
S + V +W ++N +T +TS +L N S +R A
Sbjct: 5503 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 5562
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509
N + T + +T+ KP L +++ I+L C G+P
Sbjct: 5563 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 5622
Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561
P V W +DG L + ++ + N Y+C+A N++G T
Sbjct: 5623 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5682
Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
S VV Q P T+ D++ G + ++ P PE++WYK+G
Sbjct: 5683 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5740
Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I+ + + + + I Y + A+N +GT+ + T V P
Sbjct: 5741 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5795
Score = 155 bits (376), Expect = 3e-37
Identities = 258/1109 (23%), Positives = 437/1109 (39%), Gaps = 156/1109 (14%)
Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
F++ L+ + +G +F + PR + W++ IKP+ F + D LVI+
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4743
Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
+DA T+ V +N AG A S+ +L V+ I++G
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4785
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+ + Q V +G+ ++ E ++ PE D+ WL I N ++ + D Y
Sbjct: 4786 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4835
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
++ ++K G YTV +N G+A K E P+++ L+++ + +G+
Sbjct: 4836 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4889
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
+ +V P + W KN++ +K L K G + ++ D Y +
Sbjct: 4890 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4948
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N+ G ++SA +TV +P ++ +++ V+E ++L +V P I WY+
Sbjct: 4949 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 5002
Query: 869 NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926
N + + P ++ E+ E +T S+ D G Y+ V N G+ G+ V +
Sbjct: 5003 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 5062
Query: 927 K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975
K F+ L K E EEG + L+C + + W + + D +
Sbjct: 5063 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 5121
Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026
+G D+G + K++ S K T+ P+F+ L+
Sbjct: 5122 ALDG-TATLRIRSPKKSDIGQYRVSAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 5180
Query: 1027 EVKEKDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
D V++ W +G IK + D G+ L IR+ D
Sbjct: 5181 AALPADKKEFNVKVRGLPNPTFQWFLNGIPIKLDDRITLDDMADGNYC-LTIRDVREEDF 5239
Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128
G CI ++E+ T E TV E PP L ++++ G+ E
Sbjct: 5240 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 5298
Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
+ A V WFKDG +I+ + H ++ T+DG ++KI + D G Y C E+G
Sbjct: 5299 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 5357
Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
++ A VE P IN L E V L+ ++ V
Sbjct: 5358 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 5414
Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
WYK + D+ + TL I TE+D Y CV +A T V V+
Sbjct: 5415 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 5474
Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334
P + V E E RG TL P P +W N ++++ T
Sbjct: 5475 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 5534
Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386
+ S D S SLT+ + +D GIY+ EN G A V+M + +KP GK
Sbjct: 5535 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437
P ILE+ S+ N+ E + TG N ++ + I+ + EW + + Q
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490
I+N + +R A NE + S TT+ + + + T Q P + +
Sbjct: 5654 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5709
Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+ T + ++L C P P++ WY+DG
Sbjct: 5710 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5738
Score = 143 bits (346), Expect = 1e-33
Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
+ + AP L K G ++ C+V+ PR + W++ ++ + Y++D
Sbjct: 5377 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 5436
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
ATL I + ED G + CVA NA G +++ + V+ P + E
Sbjct: 5437 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 5483
Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
G P F+K + D G L+C + P P+I W G+ +
Sbjct: 5484 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 5534
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733
IE+ CS L + EG Y A N G+A +L K K E +
Sbjct: 5535 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
PP+ I L M V G + L +V G P P++ W K+ P+ ++
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653
Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845
+ +K V DEG Y A N G A T + + +++ ++PP F + ++
Sbjct: 5654 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5713
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
E +KL +V +P+P + WY++ I++PS+ I + + + ++ D G Y+
Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5773
Query: 906 CVASNSAGKSSHGARVTI 923
+A+N +G + T+
Sbjct: 5774 VIATNPSGTAQDKGTATV 5791
Score = 142 bits (343), Expect = 3e-33
Identities = 172/749 (22%), Positives = 290/749 (38%), Gaps = 93/749 (12%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S E + F+ L+ +G + +C + G P P++ W + +++ M
Sbjct: 5064 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 5123
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
D ATL IR D G + AKN AG S+T++ V +++ G + +
Sbjct: 5124 DGTATLRIRSPKKSDIGQYRVSAKNEAG--SATSDCKVT--VTEQGEQPS---------- 5169
Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
P F K ++ +P P W G I D+ I++
Sbjct: 5170 ----------KPKFVIPLKTGAALPADKKEFNVKVRGLPNPTFQWFLNGIPIKLDDRITL 5219
Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734
+D + YC L I +V++ GT +A N G + G + P
Sbjct: 5220 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
P+ PL + G+ + + V NP + W K+ K ++ T+ +K
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 794 --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846
P + D GVY A N G AET A VE E EE P ++ TV
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
I+L +V P S+ WY++ + + ++ + + N +E D G Y+C
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 5456
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956
VA+N+ G + V + V K K ++ + T + G + L+C +
Sbjct: 5457 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 5516
Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007
KWY N + + R +I+ D G+ +C K Q T+
Sbjct: 5517 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 5575
Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055
+ + +T P+FI +L D V +V LE ++ V W +DG +
Sbjct: 5576 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 5635
Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101
I+ + ++ E + +L I+N +VHDEG Y C+ +E+ +A V
Sbjct: 5636 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5695
Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158
PP ++ + + +G E ++ + W+KDG+ + S+ IQ+++ DG
Sbjct: 5696 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5755
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
L I C DD G Y N TA
Sbjct: 5756 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5783
Score = 139 bits (337), Expect = 2e-32
Identities = 180/762 (23%), Positives = 288/762 (37%), Gaps = 105/762 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F L + P G + EC V+ P ++ WF+ I+ + ++ D +
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
I D G + CVA N G A T+ + + +H E +
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAE--TQATYQVEILEHVEE------------EKRREYA 5382
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
I P K V+ G I L C++ AIP + W G + D S+ E D
Sbjct: 5383 PKINPPLEDKT----VNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG- 5437
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQVIEPLKS 743
+ L I + + G Y VA N G + + +K E E P + L
Sbjct: 5438 --TATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVD 5495
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKALPTKSDGDTHSITILKPKKVK 798
+ +G+S L V G+P P I W +N N P + T DG S+T+ +
Sbjct: 5496 LWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC-SLTV-NESTMS 5553
Query: 799 DEGVYTLKAENSEGIAETSAVITV-------EEPTEENAEPPLFINRFQEITVKEKGTIK 851
DEG+Y +AEN+ G A+T A V E+P + +PP FI +++V I
Sbjct: 5554 DEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVID 5613
Query: 852 LVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVAS 909
L +VT P PS+ W ++ +I S N + + +L I N D G Y+CVA+
Sbjct: 5614 LECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVH-DEGTYRCVAT 5672
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQT--SHTVST 958
N G ++ + V +D + V + T EG+ + LEC+ S
Sbjct: 5673 NENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEM 5732
Query: 959 KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVV 1012
WY + ++ D +I + D G+ + I + Q+ T V
Sbjct: 5733 VWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVK 5792
Query: 1013 K------------------ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
K P+ + L++ + EK L + + + + W +DG
Sbjct: 5793 KLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDG 5852
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVTVVELPP 1107
E + P E + +L + + + D G Y C+ + SC V + P
Sbjct: 5853 ERVFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKP 5912
Query: 1108 EII-------------TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152
I T L ++ G+ TFE L G+ ++W KDG E+ I
Sbjct: 5913 RDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFEC-LPFGNPFPSIKWLKDGLELFSDEKI 5971
Query: 1153 QL--TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
++ DG Q+L + D G + C N TA E
Sbjct: 5972 KMEAAADG-TQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Score = 131 bits (317), Expect = 5e-30
Identities = 184/819 (22%), Positives = 325/819 (39%), Gaps = 81/819 (9%)
Query: 936 KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989
K + ++G + + EC T V KW + KEI + + EG
Sbjct: 2894 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2953
Query: 990 XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036
D G CIV KD +T+ V++ + PEFI LQD K + +L
Sbjct: 2954 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 3013
Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
E ++ E V W D + I + E + ++ I ++ + +G+Y+CI +
Sbjct: 3014 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 3071
Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143
T++ +TV P LQN++++ G K + KG + K
Sbjct: 3072 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 3130
Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195
++I S+ I + D ++ I +D Y NS TA T VE P
Sbjct: 3131 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 3190
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253
L+ V + + V++ DV W+K K V ED + + TL
Sbjct: 3191 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 3247
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309
++++ D +YT + T + + EV + P V +K TL V
Sbjct: 3248 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 3307
Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P+ EW+ + + ++ H ++ S S S+TIK D+G Y R N G
Sbjct: 3308 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 3367
Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
A E N ++ PP K + LE+ + T + VE+ + DT
Sbjct: 3368 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 3422
Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
I ++ + QT++ +L N + + Y+ + + + TT + +I+++
Sbjct: 3423 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 3480
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534
P + L+ + E ++L G P P V W++D K + K
Sbjct: 3481 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFGKDEGSGHHT 3540
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593
Y C A N+ GE +T+ + +Q++ + + +K + + G +
Sbjct: 3541 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 3600
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651
+EG P PEV W+K+G + D ++ I K + + + IK+ + KYT +A+N A
Sbjct: 3601 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3660
Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686
G LK+ ++K + E + E +E+ +E
Sbjct: 3661 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3699
Score = 131 bits (316), Expect = 6e-30
Identities = 145/606 (23%), Positives = 250/606 (41%), Gaps = 53/606 (8%)
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P PDI W ++ DE + + D + I V+ G YT +A N
Sbjct: 570 KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626
Query: 716 EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
G+AS ++ EKE PP + L+ ++G+ + +V G P P + W +++
Sbjct: 627 YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686
Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
P++ + DG T + I + + D GVYT+K +N G E+ A + V+ ++N
Sbjct: 687 PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
P F + + E ++ + +T +P P I W+ N + +S SE + + L
Sbjct: 746 VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948
I +V D G C SN G +S R+ + V TF K L+ +E TV+
Sbjct: 806 TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863
Query: 949 ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
E S T K+ +G + EI+ +G G I +++
Sbjct: 864 EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923
Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
E+ L V++ + P F++ ++D VK + A+ E + + +V W +G
Sbjct: 924 HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104
+ E H KL I S G C + R E+ V + +
Sbjct: 984 HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+
Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101
Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + ++DAGE NS + A LTV++ PEF L P + LTVE
Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPF-----APEFDLRPVS----LTVE 1152
Query: 1220 IPDETL 1225
E +
Sbjct: 1153 KGSEAV 1158
Score = 130 bits (313), Expect = 1e-29
Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K +++ P F + L G + +C V G P P+I W+R +++ +
Sbjct: 5477 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 5536
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
D +L + E D G + C A+NA G A + V+ L
Sbjct: 5537 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 5582
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
+ EG PP F + V G+ I LEC++ +P P + W G ++ D
Sbjct: 5583 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5640
Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732
+ E+ +Y L+I N EGTY VA N G A+ +++ G
Sbjct: 5641 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5698
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789
+PP+ + + +G+ + L +V +P P + W K+ A+ T SD S+
Sbjct: 5699 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5754
Query: 790 ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832
T+L P V D+G+Y + A N G A+ TV++ P + A +
Sbjct: 5755 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5814
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890
P + + I + EK + +L + + +P P+I W+++ E + P + ++ DG EL
Sbjct: 5815 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5873
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
V+ + + D+G Y+CVA N+ G + V +
Sbjct: 5874 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5905
Score = 126 bits (303), Expect = 2e-28
Identities = 205/1011 (20%), Positives = 393/1011 (38%), Gaps = 84/1011 (8%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P ++ K Q V++ L +V + W G+EI + ++V+ + CS
Sbjct: 1885 PKLTRDLKLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVSKDDQFEFRCS 1942
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGES 751
+ + F GT +VVA N G LK+ KE P+ + L+ M V +G++
Sbjct: 1943 I----DTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDT 1998
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
V V+ P W +N ++ + K++ + S+ I +D G T++A
Sbjct: 1999 V--QMDVIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLII---PNAQDSGKITVEA 2053
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G +E+SA +TV P + P+ ++ + +T+KE T + A ++ P P++ W
Sbjct: 2054 SNEVGSSESSAQLTVNPP----STTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWT 2109
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE- 926
N +I+ S TIT + L I+N E +G K A NSAG+ S A + ++
Sbjct: 2110 INEKIVEESRTITTIKTEDVYTLKISNPKIE-QTGTVKVTAQNSAGQDSKQADLKVEPNV 2168
Query: 927 KVTFVKHLQKSYETEEGKTVILECQ---TSHTVSTKWYHNKKEISGMDHREIIQEGRXXX 983
K K +EG+ + + S W N + ++ D +++ G
Sbjct: 2169 KAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTY 2228
Query: 984 XXXXXXXXXDV-GVI----KCIVKDQETSTMLVVK--ETIPEFIRKLQDFEVK-EKDVAI 1035
++ G + K + ETS + V PEF++ Q+ E E V
Sbjct: 2229 HVTIAEAKPEMSGTLTPKPKNAAGECETSPKVTVNGGNKKPEFVQAPQNHETTLEGSVKF 2288
Query: 1036 LEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG----EYSCI 1090
+ +V W + ++I+ ++ K + + I+ + G E +
Sbjct: 2289 SAIVTGKPIPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENV 2348
Query: 1091 LRDESCTAEVTVVELP--PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQ 1147
TA++ V + P+ T + +++V +G F + + V W +G +
Sbjct: 2349 SGKVQATAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVS 2408
Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEE--PSINFTLR 1201
+I +T + ++I + AGE SCE VG+ K L V++ + F
Sbjct: 2409 KHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKN 2468
Query: 1202 LPEFILVPAN---TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI--SDVKKRTLIIR 1256
L + ++ DA L + P +TW K I + ++ D + I++
Sbjct: 2469 LEDRLITEGELTLMDAKLNIVKPKP--KITWLKDGVEITSDGHYKIVEEEDGSLKLSILQ 2526
Query: 1257 KCTEDD-----QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
ED + E + + ++ + P + G + +
Sbjct: 2527 TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLI 2586
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
P P +W + ++++ + T+ S + ++ I V G K N G
Sbjct: 2587 TGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKAGEVST 2646
Query: 1372 EMNVTILDKPSPPGKPNIL------EIDSSSIN-ICWDEPENTGNSTIIYYVVEYQEIDT 1424
E + ++ P P L E D+ + + EPE ++ + V ++++
Sbjct: 2647 EGPLKVV-APIPVEFETSLCDATCREGDTLKLRAVLLGEPE-----PVVSWYVNGKKLEE 2700
Query: 1425 TEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
++ I + + T T +I+++ + S + A+NE SE T ++ + + P
Sbjct: 2701 SQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYG-KATSEAT----LLVLPRGEPPD 2755
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK-----LKTAKATYENRXXXXXX 1538
+ L N+ + +F G P+P +TWY + K+ L T +
Sbjct: 2756 FLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINS 2815
Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE 1589
C A ND GEV + + + + S + + + VGD+
Sbjct: 2816 FNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDD 2866
Score = 126 bits (303), Expect = 2e-28
Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+ + AP +E L P+ + + C+ G P+P I WF+ + P Q+ D
Sbjct: 5810 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5869
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
V LV+ +DAG + CVA+N G S+ T V D
Sbjct: 5870 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5915
Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
+ I EG P F+ + G + EC P P I WL G E+ DE I +
Sbjct: 5916 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5975
Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731
+D L +++V EG + VA N G AS L I+ GE
Sbjct: 5976 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 732 KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782
E P++ L +M + +G V + G P PT+ W K+ + + K +
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834
+ H + I+ DEG Y+L+A N G A+T + + P +A+ PP
Sbjct: 6093 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 6151
Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893
F+ + + V V +P P + W+ N + I P I Q+ G + L+I
Sbjct: 6152 FVRQLKNKHVFNHMPTIFDCLVVGHPGPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 6211
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ E D+G+Y A NS G +S A + + V + +K
Sbjct: 6212 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 6249
Score = 124 bits (300), Expect = 5e-28
Identities = 225/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
+P+ L D YT E I++ + E P V L P+G
Sbjct: 4839 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4891
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
F+ +V P Q+ W++ IKP+ + L I +D + V NA
Sbjct: 4892 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4950
Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
AG S+ L V P I++G+ ++P+
Sbjct: 4951 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4983
Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
+ L+ ++ IP+ I W G+E+ PD + E L I + KK G Y
Sbjct: 4984 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 5040
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764
VV N +GE V+ +K+ + P + PLK V +G+ + L + G P P
Sbjct: 5041 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 5100
Query: 765 TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
+ W K+ ++ + DG T ++ I PKK D G Y + A+N G A +
Sbjct: 5101 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSPKK-SDIGQYRVSAKNEAGSATSDCK 5158
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+TV E E+ ++P F+ + + +V P P+ W+ N I + I
Sbjct: 5159 VTVTEQGEQPSKPK-FVIPLKTGAALPADKKEFNVKVRGLPNPTFQWFLNGIPIKLDDRI 5217
Query: 880 T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928
T + N L I +V E D G KC+A N G + H D+
Sbjct: 5218 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276
Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985
G + +EC + T +W+ + K+I H EI
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336
Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030
D+GV C+ ++ ET V +E P+ L+D V
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396
Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
L ++++ A VVW +DG ++ + +E+ G L I +++ D G Y
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 5455
Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
C+ + SC+ V V + P L + ++G+ T + +T GD
Sbjct: 5456 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 5514
Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
++W+++G ++ I+ + DG L + + + D G Y CE G +K A
Sbjct: 5515 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 5573
Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233
V E+P ++ + P+FIL ++ L I E V W K
Sbjct: 5574 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 5632
Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283
+ + +F ++ K L I+ T D+ Y CV + +TTK V +
Sbjct: 5633 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5692
Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
PP+ + R G + L A P P W + I+ + S+
Sbjct: 5693 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5752
Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
A+L I D GIY++ N G A + T+ P G
Sbjct: 5753 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5799
Score = 116 bits (278), Expect = 2e-25
Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
EKP +E P F+ +L G+ + EC+V G P P + W + + F+
Sbjct: 5585 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5643
Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ V L I+ D GT+ CVA N G S+TT+ V D G V
Sbjct: 5644 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5698
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
PP F+ K EG + LEC++ A P P++ W G + P
Sbjct: 5699 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5744
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
+ I +++ D + L I + +G Y V+A N G A +K +G +
Sbjct: 5745 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5801
Query: 733 -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778
+ P+++EPL+++ + + +S L + G+P+PTI W K+ + P L
Sbjct: 5802 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5861
Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829
D ++ +D G Y AEN+ G A TS + V +P +
Sbjct: 5862 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5921
Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+ P F K ++ NP PSI W ++ + E I + +
Sbjct: 5922 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5981
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944
+I + + + G ++CVA+N G +S A + I+ ++ + L + + E EE K
Sbjct: 5982 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 6037
Score = 111 bits (268), Expect = 4e-24
Identities = 145/628 (23%), Positives = 251/628 (39%), Gaps = 53/628 (8%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
Q S + +V G P P ITW K++ + + SD D + P +V D G YT
Sbjct: 561 QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N G A TSA V + E+ A PP F+ + ++ KE I V P P +
Sbjct: 621 CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
W +++ + PS +DG+ +L I + + D+G Y N G A + +
Sbjct: 680 VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738
Query: 924 -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
D +K Q + E +EG+ V + + + + W+ N K +S + + I
Sbjct: 739 ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798
Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031
E G++ C ++ S + V P F + L+D V+EK
Sbjct: 799 EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858
Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088
+ EV+++ + + G+ +K + + ++ I NTS+ HD GE
Sbjct: 859 STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917
Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137
++E TAE +TV + P + +++Q V G A FE + + V
Sbjct: 918 AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977
Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
WF +G ++ Q S +++ KL I AG C VG + A L V
Sbjct: 978 TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035
Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
P + P+F+ + + D + E+ E VTWY K ++ +++ +
Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301
+ I+ +D E V +++ + KL V+ F P+ +++
Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
GS+ P P EW VN + ++
Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVR 1181
Score = 108 bits (260), Expect = 4e-23
Identities = 120/526 (22%), Positives = 205/526 (38%), Gaps = 39/526 (7%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E PP F K + + EG I EC + PEP++ WL + + P + + +
Sbjct: 644 EAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ-- 701
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIV 746
+ L+I + + G YTV N G L ++ + P+ ++ +
Sbjct: 702 --TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVEC 759
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGVYT 804
+GE V + + G+P P I W N KP+ I IL K V +G+ T
Sbjct: 760 DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVT 819
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
+ N G A + V P PP F ++ TV+EK T+ V+ P P++
Sbjct: 820 CQGSNRLGSASCDGRLKVRVP----PAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTL 875
Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
T+ + + E + + + I N + G+ A N G + AR+T+
Sbjct: 876 TFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV 935
Query: 924 DVEK------VTFVKHLQ-KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREII 976
+ E+ TF+K ++ ++ +T E + + W+ N ++ +
Sbjct: 936 EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMD-QGSPGVK 994
Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----KETIPEFIRKLQDFE 1027
E G + C ++ ET LVV ++ P+F+ L D
Sbjct: 995 IEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKT 1054
Query: 1028 VKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
+ + EV + E V W GE +K E G I K+ I+N + D GE
Sbjct: 1055 ETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSI-KISIKNIKIEDAGE 1113
Query: 1087 YSCILRD----ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATF 1126
+ + + A++TV + P PE R + V KG++A F
Sbjct: 1114 IRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVF 1159
Score = 107 bits (257), Expect = 9e-23
Identities = 205/1012 (20%), Positives = 376/1012 (37%), Gaps = 71/1012 (7%)
Query: 726 KIKTGEKEP-PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKS 782
K EK P P++ LK V + + + +VV W + K + T S
Sbjct: 1875 KSPEAEKPPAPKLTRDLKLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVS 1932
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
D + G ++ A N+ G ET + V E +E +P F ++ +++
Sbjct: 1933 KDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPE-FTDKLRDM 1991
Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDS 901
V + T+++ +P+ WY+N ++ + +T + L+I N DS
Sbjct: 1992 EVTKGDTVQMDVIALHSPL--YKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DS 2046
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILECQTSH--TVST 958
G ASN G S A++T++ T V KS +E +T + S +
Sbjct: 2047 GKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTV 2106
Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKE 1014
KW N+K + I+ G +K ++ Q++ L V+
Sbjct: 2107 KWTINEKIVEESRTITTIKTEDVYTLKISNPKIEQTGTVKVTAQNSAGQDSKQADLKVEP 2166
Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEIIKPKKNKYDFEKRGH 1070
+ P+F +L D E + +E++ S +V W +G+ + +
Sbjct: 2167 NVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDG 2226
Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVV--ELPPEIITRLQNQKVNKGNKA 1124
+ I G + ++ + E VTV PE + QN +
Sbjct: 2227 TYHVTIAEAKPEMSGTLTPKPKNAAGECETSPKVTVNGGNKKPEFVQAPQNHETTLEGSV 2286
Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV- 1180
F +T K V W+ + ++ S +++ + K ++I ++ G E
Sbjct: 2287 KFSAIVTGKPIPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAE 2346
Query: 1181 ---GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
G + TA L V++ + FT + + V D T + V W
Sbjct: 2347 NVSGKVQATAQLKVDKKTEVPKFTTNMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGE 2405
Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
+ T+ + T+ I T + CE T + K +L V+ V P
Sbjct: 2406 PVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTF 2465
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTI 1347
+ I G ++TL+ P+P W+ + I H K + S L+I
Sbjct: 2466 AKNLEDRLITEG-ELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSI 2524
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN- 1406
+ + D G ++ E+ G A+ ++ ++ K P KP + D + IN+ +
Sbjct: 2525 LQTKLEDKGRITIKAESEFGVAECSASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLEC 2582
Query: 1407 ----TGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460
TG+ T + + + Q + TE + N T I + + + + + A N+
Sbjct: 2583 KLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA- 2641
Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
+ S T KV+ ++ E L + T + ++L + G P+P V+WY +GK
Sbjct: 2642 -GEVS-TEGPLKVVAPIPVE---FETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGK 2696
Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYK----CIAFNDHGEVETSCVVGIQQKPVITIS 1576
KL+ ++ + Y C A N++G+ + + + +
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 1577 NEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
E + + + G + + V G P P + WY N ++ N Y I T +KTS + I
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 1636 KRS-HSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVT 1684
H + +A N AG S + Y D S+ E E + +T
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLT 2868
Score = 102 bits (244), Expect = 3e-21
Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%)
Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144
+ DES E+ P P+ IT++++ K KG+ A FE + TKG +W KDG
Sbjct: 2867 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2925
Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194
EI+ I++ T G + Q+L + + +DAG+Y+C V G C A LTV E
Sbjct: 2926 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2985
Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246
+ PEFI+ T + +E I + V+W + K++ +++ +
Sbjct: 2986 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 3045
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304
V++ T+ + + Q +YTC+ + + T+K + + V P + + G
Sbjct: 3046 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 3103
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356
+ L + PQP+ ++ S+ K + K T S I+ + + I ++ D
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
YK N+ G A +T + +P + + + E + G++ + +
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
+ + + +K +T ++ T + ++ A A N +++S E +
Sbjct: 3223 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 3281
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527
++ PT + L + NE L+ GVP P V W +DG+ ++T AK
Sbjct: 3282 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 3337
Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586
Y C A N GE +T + + V E + + K
Sbjct: 3338 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 3397
Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644
+ ++ + G P P V W+K+ + D + I T + + I + ++ Y+
Sbjct: 3398 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 3457
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688
A N AG + + PE +R + RE T++ K
Sbjct: 3458 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 3502
Score = 97.1 bits (231), Expect = 1e-19
Identities = 113/461 (24%), Positives = 185/461 (40%), Gaps = 44/461 (9%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F + L K + STV FE V G+P P +T+ +K ++ D +
Sbjct: 844 PTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRIS 903
Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + G A+N G A S L VE + S
Sbjct: 904 IPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA------------------ 945
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
PTF K + Q V G + E + P P++ W G ++ D+ S ++ +
Sbjct: 946 -----PTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM--DQG-SPGVKIEA 997
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
H + L I + + GT A N G E +V+ +K+PP+ +E L
Sbjct: 998 HNHDHKLTIDSAQ--YAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTE 1055
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITI-LKPKKVKDEGVYT 804
+V+ +V G P+PT+TW + +K + SI I +K K++D G
Sbjct: 1056 TVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A NSEG ET A +TV++ P F R +TV++ A P+P+
Sbjct: 1116 AVATNSEGSDETKAKLTVQK----KPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTY 1171
Query: 865 TWYRNNEIISPSET---ITQN---FDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917
W N + + +T++ DG +I + T SE++ VA N+ G
Sbjct: 1172 EWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEET 1231
Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
GA++TI+ +K + V Q +E K + + + + +T
Sbjct: 1232 GAQLTIEPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 96.7 bits (230), Expect = 2e-19
Identities = 146/708 (20%), Positives = 276/708 (38%), Gaps = 67/708 (9%)
Query: 1046 DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100
D+ W +D ++ + +++ + ++ G + I V D G Y+C+ +E S +A
Sbjct: 578 DITWYKDDVQLHEDERHTFYSDEDGFFA-MTIDPVQVTDTGRYTCMATNEYGQASTSAFF 636
Query: 1101 TVVEL-----PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL 1154
V+++ PP +T+L++++ +G+ FE E+ + + W D ++ S+ +L
Sbjct: 637 RVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRL 696
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE-EPSINFTLRLPEFILVP 1209
DG+ KL+I D DD G Y+ ++ G+ + A L V+ +P N PEF
Sbjct: 697 QYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVA--PEFQATI 754
Query: 1210 ANTDA-------YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+ + +V D ++ W+ + ++EK IS+ L I+ T
Sbjct: 755 EYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHF 814
Query: 1263 QCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
TC L A +LKV V PP + ++ S V VD +P+P
Sbjct: 815 DGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPT 874
Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
+ + K +K + + S+ ++ D I + +N G A+ +
Sbjct: 875 LTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVA-KAQNEHGTAESRARL 933
Query: 1376 TI-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNI 1433
T+ ++ P L+ I D+ TG + V W I+ +
Sbjct: 934 TVEQEEEESRSAPTFLK----DIE---DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM 986
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEK-PLK- 1489
+ ++ N ++ + + A ++ + +P +K P K
Sbjct: 987 DQGSPGVKIEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKF 1046
Query: 1490 -NITTEPNEDIELTCIFG----GVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX 1540
I + E ++ T +F G P+P VTWY G++LK + ++
Sbjct: 1047 VEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNI 1106
Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGI 1599
+ +A N G ET + +Q+KP + + G E + +A GI
Sbjct: 1107 KIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGI 1166
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--------TIEASNTA 1651
P P W NG K+ + +E T+++++V L ++ Y ++ A NT
Sbjct: 1167 PLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTL 1226
Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
G L + +P K V +++S V E + + E T
Sbjct: 1227 GAEETGAQLTI--EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272
Score = 86.2 bits (204), Expect = 2e-16
Identities = 151/715 (21%), Positives = 276/715 (38%), Gaps = 68/715 (9%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P F+ KL+D E KE DV E E+ ++VW D + ++P + + + G KL
Sbjct: 648 PAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHD-FRLQYDGQTAKLE 706
Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PEIITRLQNQKVNKGNKAT 1125
IR+ D G Y+ +++E AE+ V P PE ++ + ++G +
Sbjct: 707 IRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVR 766
Query: 1126 FEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179
F+ +T GD + WF +G + S ++ + L I D G +C+
Sbjct: 767 FKSVIT-GDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNR 825
Query: 1180 VGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI---PDETLDVTWYKKKSV 1235
+G++ C L V P T P E V + V++ P+ TL T K+
Sbjct: 826 LGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELK 885
Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE-----F 1286
+ + D R I + E + A+S +L VE E
Sbjct: 886 NGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA 945
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASL 1345
P + D E + +K G + P P W +N K+ + K + L
Sbjct: 946 PTFLKDIE-DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHDHKL 1004
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-----DSSSINIC 1400
TI + AG R EN G + + + +L P +EI ++ +
Sbjct: 1005 TIDSAQY--AGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVV 1062
Query: 1401 WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458
++ E T+ +Y+ + +E+ ++ + ++ + + SI+N+K + RA A N
Sbjct: 1063 FEVRVEGEPKPTVTWYL-KGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATN- 1120
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
S+ S+ T+ K+ + K +P + ++T E + + G+P P W +
Sbjct: 1121 ---SEGSDETKA-KLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVN 1176
Query: 1519 GKKLKT----AKATYENRXXXXXXXXXXXXXXXY--------KCIAFNDHGEVETSCVVG 1566
G+K++ A+ T + Y +A N G ET +
Sbjct: 1177 GRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLT 1236
Query: 1567 IQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I+ +K + + +D+ +V E + ++ P L + K ++T E
Sbjct: 1237 IEPKKESVVVEKQDLSSS-EVQKE--IAQQVKEASPEATTTITMETSLTSTKTTTMSTTE 1293
Query: 1626 KTSVIR--IKELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
TS + E K S S S T+ + G + +++ + SK + +RE
Sbjct: 1294 VTSTVGGVTVETKESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVRE 1348
Score = 70.9 bits (166), Expect = 9e-12
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
+Y E + + + P+PDI W F+G +I S + L IT K
Sbjct: 6419 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 6478
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y A N G+A I++ + T P I+PL + + + + +V G P
Sbjct: 6479 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
P + W K +P+ + DG I+ +D G+Y+ A N G A TS
Sbjct: 6535 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 6594
Query: 820 ITVEEPTEEN 829
+TVE + N
Sbjct: 6595 VTVEAEGDYN 6604
Score = 60.5 bits (140), Expect = 1e-08
Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531
K+++ ++P L++ TT+ +E + L C G P+PKV+W D K + T E+
Sbjct: 2987 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 3046
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589
Y CIA N G +T + +Q + PV T ++++ K +G++
Sbjct: 3047 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 3103
Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641
+++ ++G P P V +Y K K+ + I + + R I ++ +
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163
Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
Y A+N+ G TS+ ++T KV + P +G +E + +E K +E
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
K E N+ K + + V T +++ + A NP G +E+
Sbjct: 3223 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 3273
Score = 57.6 bits (133), Expect = 9e-08
Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 3/149 (2%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+Q P FVE L K +TV FE +VEG P+P +TW+ + +K S ++ D
Sbjct: 1038 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 1097
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXX 622
++ + I+ + EDAG VA N+ G + +L V+ P + V
Sbjct: 1098 SI-KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSE 1156
Query: 623 XXXADILEGIP-PTFSKKPKAQYVDEGSD 650
+ GIP PT+ + V +G +
Sbjct: 1157 AVFSAHAFGIPLPTYEWSVNGRKVRDGQE 1185
Score = 57.2 bits (132), Expect = 1e-07
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 9/171 (5%)
Query: 1507 GVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P +TWY+D +L T + + Y C+A N++G+ T
Sbjct: 573 GYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQAST 632
Query: 1562 SC---VVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
S V+ ++++ ++ K K GD +EG P PE++W + L
Sbjct: 633 SAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSH 692
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
++ + +T+ + I++ + + YT++ N G+ + L V P K
Sbjct: 693 DFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDK 743
Score = 57.2 bits (132), Expect = 1e-07
Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565
S+ P F +KLRP + T+ + V G P P + WF+ I D+
Sbjct: 3479 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFGKDEGSGH 3538
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608
TL I++ ED G +TC A N AG A +T + V EAPL G
Sbjct: 3539 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 3585
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
++P + +PL+NI + L C F G P+P + W++DG+++ + +
Sbjct: 5813 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5872
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581
Y+C+A N +G TSC V + +KP I S + K
Sbjct: 5873 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5932
Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639
++ K GD + G P P + W K+G +L +D++ + + T + + ++
Sbjct: 5933 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5992
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ A+N GT+S + L +
Sbjct: 5993 EGYFRCVATNEHGTASTKAELVI 6015
Score = 55.6 bits (128), Expect = 4e-07
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
D YT +Q + K +F + ++ +AP F + +G V+F+ + G
Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773
Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
P P+I WF + S+ + + +D + L I++V G TC N G AS
Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832
Query: 596 TELIVEAP 603
L V P
Sbjct: 833 GRLKVRVP 840
Score = 55.6 bits (128), Expect = 4e-07
Identities = 77/396 (19%), Positives = 158/396 (39%), Gaps = 32/396 (8%)
Query: 1315 PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADV 1371
P+P+ +W N + +K K ++D + LT+ + D Y+ N G +DV
Sbjct: 3947 PKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDV 4006
Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
+ V + +P + I E + +G + + + + + + +
Sbjct: 4007 TLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFE 4066
Query: 1432 NITK-TQTS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKP 1487
+ TQ I++ KT+ +R N+ ++++ + T + S T ++K
Sbjct: 4067 STDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKG 4118
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXX 1542
L ++ I L+ G P+ V WY+ + + +++ T E+
Sbjct: 4119 LTDVNVTQGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEM 4177
Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIE 1597
Y+ + D VE+S V + K IS K Q G ++ IE
Sbjct: 4178 SDTGAYRVVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIE 4236
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P +V WYKNG+++++ K ++ + + I + + +Y++ A+N AG +
Sbjct: 4237 G-KPKDVKWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESK 4293
Query: 1658 VTLKVYDKPSKPEG--PVIMREISRESVTIEWKPPL 1691
+ V KP G P +++ + ++ K P+
Sbjct: 4294 AKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 4329
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
++P PL +P + + C+ G P P + W +DG +L + +A +
Sbjct: 5923 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5982
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
++C+A N+HG T +G + P + E+ K + +
Sbjct: 5983 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 6042
Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
G E V +I GIP P V WYK+G ++ D K T + + I
Sbjct: 6043 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 6102
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+Y++EA+N G++ E +L +
Sbjct: 6103 NASPDDEGEYSLEATNKLGSAKTEGSLNI 6131
Score = 53.6 bits (123), Expect = 1e-06
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
+ +++ + V G P P I W + P + G + + + ++ G
Sbjct: 6423 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 6482
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
Y A+N G A+ + I V+ T N PL +N+ T +++ RV P
Sbjct: 6483 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 6535
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
P + W + I S I DG + +I N DSG Y CVA N AG+++ V
Sbjct: 6536 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 6595
Query: 922 TIDVE 926
T++ E
Sbjct: 6596 TVEAE 6600
Score = 53.2 bits (122), Expect = 2e-06
Identities = 26/93 (27%), Positives = 49/93 (52%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
I + D+G ++CVA N AG A+++ + VEA
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 6599
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559
Q AP+F ++L+ K G + C V+G P+P + + F +T ++ S +
Sbjct: 3083 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 3142
Query: 560 YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612
+D N +VI ++ ED ++ +A N+ G A+ST+++ VEAP+ + G + T
Sbjct: 3143 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 3198
Score = 51.6 bits (118), Expect = 6e-06
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
L V E + + AP F+ L+ K T V EC+V G P+P+++W I +Q
Sbjct: 2979 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 3036
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604
+ + V + I G +TC+A+N G + + L V EAP+
Sbjct: 3037 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 3088
Score = 50.0 bits (114), Expect = 2e-05
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
S+ + +V GYP P ITW++ + + Y D+D + I V D G +TC+
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 585 AKNAAGFASST 595
A N G AS++
Sbjct: 623 ATNEYGQASTS 633
Score = 49.2 bits (112), Expect = 3e-05
Identities = 49/235 (20%), Positives = 88/235 (37%), Gaps = 12/235 (5%)
Query: 1466 ETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
ET KV++ K + P L+++ + +++ I + P WY++G L+
Sbjct: 1965 ETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLED 2022
Query: 1525 AK--ATYENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNE 1578
K T +N + A N+ G E+S + + P++ +
Sbjct: 2023 GKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPK 2082
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ K E+ T I G P P V W N +E + E ++I K
Sbjct: 2083 SVTIKETETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNPKIE 2140
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692
+ + A N+AG S + LKV P+ + +++ E + W LD
Sbjct: 2141 QTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 2195
Score = 47.2 bits (107), Expect = 1e-04
Identities = 58/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
+E P R L + + E +V + V T V W +DG+ I P + F
Sbjct: 6034 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 6093
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
I L I N S DEGEYS ++ +A+ + ++ PP +
Sbjct: 6094 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 6153
Query: 1111 TRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
+L+N+ V F+ + + V WF +G +I I++ + G L I D
Sbjct: 6154 RQLKNKHVFNHMPTIFDCLVVGHPGPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 6213
Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
L+DAGEY G++ +A+L V P ++ E + P T+ Y
Sbjct: 6214 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 6264
Score = 44.4 bits (100), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Query: 1372 EMNVTILDKPSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWIS 1429
E+N L P+PP + P I E+ + + W + + YV+E +E+ +W
Sbjct: 6268 ELNTASL--PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSL 6325
Query: 1430 VK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
++ NI + ++NL+ SY+FR A N ISD S
Sbjct: 6326 LEYNIPEPVCKVRNLELGKSYQFRVRAENIYGISDPS 6362
Score = 39.5 bits (88), Expect = 0.026
Identities = 45/203 (22%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXX 1534
P + + L N++ +E+ G+P P V WY+DG+++ K T E
Sbjct: 6038 PRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIH 6097
Query: 1535 XXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE------------DIK 1581
Y A N G +T + I + I ++E +K
Sbjct: 6098 HLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 6157
Query: 1582 QKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSH 1639
KH + ++ G P PEV W+ NG K+ I + S + I +
Sbjct: 6158 NKHVFNHMPTIFDCLVVGHPGPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLED 6217
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ +Y A N+ G++S L V
Sbjct: 6218 AGEYVATAKNSHGSASSSAVLDV 6240
Score = 39.1 bits (87), Expect = 0.034
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++
Sbjct: 6402 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 6461
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
Y + TL I E+ G + C AKN G A
Sbjct: 6462 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 6495
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472
E R A+ Y + + EAI L +G+ + +LD N W V+ K GWVP
Sbjct: 61 ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120
Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500
Y + Y Q++ +I+ + + ++
Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
+ G P P++ WYK+ +L D+ + + E + I ++ + + +YT A+N G +
Sbjct: 571 VTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQA 630
Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678
S +V + P + ++
Sbjct: 631 STSAFFRVLKVEKEAAPPAFVTKL 654
Score = 34.3 bits (75), Expect = 0.97
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPE-SNGGSPITNYIIEFKTVKGKSWTKI-VTVGGS 1921
TPP R + E T +TL W + + P Y+IE + + K W+ + +
Sbjct: 6276 TPPD--RGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEP 6333
Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
V + + N++ FR+ AEN G+S P+
Sbjct: 6334 VCK--VRNLELGKSYQFRVRAENIYGISDPS 6362
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1786 ITWFPSEKNGGS-PIIDYKVEIKQ-EGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYAR 1842
++W P+++ P + Y +EI++ K+W +++ L + +YQFR+ A
Sbjct: 6294 LSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAE 6353
Query: 1843 NEIGTSLP 1850
N G S P
Sbjct: 6354 NIYGISDP 6361
Score = 31.9 bits (69), Expect = 5.2
Identities = 35/193 (18%), Positives = 66/193 (34%), Gaps = 5/193 (2%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYC 692
P F +P + V++GS+ + IP P W G ++ E V +
Sbjct: 1140 PEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGA 1199
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S+L I + E + ++V E T E + V+ + + + +
Sbjct: 1200 SILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKESVVVEKQDLSSSEVQKE 1259
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYTLKAE 808
I +P T T T + T+ ++ K+ + E T+
Sbjct: 1260 IAQQVKEASPEATTTITMETSLTSTKTTTMSTTEVTSTVGGVTVETKESESESATTVIGG 1319
Query: 809 NSEGIAETSAVIT 821
S G+ E S ++
Sbjct: 1320 GSGGVTEGSISVS 1332
Score = 31.5 bits (68), Expect = 6.8
Identities = 48/230 (20%), Positives = 83/230 (36%), Gaps = 16/230 (6%)
Query: 180 EAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLT-----PIK 234
E ++ ESE+ ++TS + PEK+ D+K S T + +T P+K
Sbjct: 1508 ETTMTTEMTHESEE--SRTSVKKEKTPEKV---DEKPKSPTKKDKSPEKSITEEIKSPVK 1562
Query: 235 IERKEMEVSTPQHAETVD--GPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSW 292
E+ +V + T P+ T K P+ + +K
Sbjct: 1563 KEKSPEKVEEKPASPTKKEKSPEKPASPTKKSENEVKSPTKKEKSPEKSVVEELKSPKEK 1622
Query: 293 PPESI--KPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYED 350
PE KP + ++K K +K + P + P +D
Sbjct: 1623 SPEKADDKPKSPTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDD 1682
Query: 351 IVES--KKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDE 398
V+S KK+++ E++ KE PE+ + KS +K E +E
Sbjct: 1683 EVKSPTKKEKSPQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEE 1732
Score = 31.5 bits (68), Expect = 6.8
Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 161 SQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQT 220
S E +V P + E+A+ +PK + E+ K++ + + P K +K +
Sbjct: 1710 SPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVKSPTKKEKSPEKSAEEK 1769
Query: 221 PTSFNKRSKLTPIKIERKEMEVST 244
P S K+ +P+K+ E++ T
Sbjct: 1770 PKSPTKKES-SPVKMADDEVKSPT 1792
>Z47070-8|CAA87345.1| 5198|Caenorhabditis elegans Hypothetical protein
F15G9.4b protein.
Length = 5198
Score = 213 bits (520), Expect = 1e-54
Identities = 282/1187 (23%), Positives = 464/1187 (39%), Gaps = 142/1187 (11%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + EC +E ITW RQ K Q + + L I + PEDA +++C
Sbjct: 2957 GDPLTLECPIEDTSGVHITWSRQFG--KDGQLDMRAQSSSDKSKLYIMQATPEDADSYSC 3014
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+A N AG A + ++ V P G + EGIPP
Sbjct: 3015 IAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCR-TEGIPP--------- 3064
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
PE I+W G+ I+ ++ + D+ L+I N+K
Sbjct: 3065 -----------------PE--ISWFLDGKPILEMPGVTYK-QGDLS-----LRIDNIKPN 3099
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
QEG YT VA N+ G A ++I EPP+V+ + M V +G + +V GNP
Sbjct: 3100 QEGRYTCVAENKAGRAEQDTYVEI----SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPE 3155
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
P + W K+ +P + S L+ + D G YT A N G ++T+ + V
Sbjct: 3156 PVVNWLKDGEPYTS-DLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV- 3213
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
PP + + + KE T + +VT PVP +TW RN + I + F
Sbjct: 3214 ------LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-------EQF 3260
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
N L I N + D G Y C+ASN AG + A IDV K TF H + ++ E
Sbjct: 3261 ---NPVLHIRNA-TRADEGKYSCIASNEAGTAV--ADFLIDVFTKPTFETH-ETTFNIVE 3313
Query: 943 GKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
G++ +EC+ H T W + + MD+ II R D G+ C+
Sbjct: 3314 GESAKIECKIDGHPKPTISWLKGGRPFN-MDN--IILSPRGDTLMILKAQRFDGGLYTCV 3370
Query: 1001 V------KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE 1054
+Q+ + K I E I + V ++ + + + T V W+R G+
Sbjct: 3371 ATNSYGDSEQDFKVNVYTKPYIDETIDQTPK-AVAGGEIILKCPVLGNPTPTVTWKR-GD 3428
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEIIT 1111
P +++ ++ I + + D G+YSCI +E+ T V P +
Sbjct: 3429 DAVPNDSRHTIVNNYDLK---INSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR 3485
Query: 1112 RLQN-QKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
+ N +V + + T + +T + WF+ + + ++ DG + I
Sbjct: 3486 KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDG--SHITINKAK 3543
Query: 1170 LDDAGEYSC----EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223
L D G+Y C E G S IL + P I+ + + + + A T YL I
Sbjct: 3544 LSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVART-IYLECPISGIP 3602
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
DV W K I T+ +++ T I DQ YTC + K++ +
Sbjct: 3603 QPDVIWTKNGMDINMTDSRVILAQ-NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 3661
Query: 1282 EVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDE-----WIVNSKIIKKCKHTK 1335
+V+ PP+ + + IKR G +TL + D+ W +S+ +
Sbjct: 3662 DVLS-PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDN 3720
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I LTI + +AG+Y N G A +E V IL SPP +++I +
Sbjct: 3721 VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL---SPP----VIDISRN 3773
Query: 1396 SINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-SVKNITKTQT--------SIQNLKT 1445
+ +P+ N TI+ V + +W+ + K +T + +Q L+T
Sbjct: 3774 DV-----QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRT 3828
Query: 1446 NSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+S + ++ A N+ + + + + + S + P+K + E I L C
Sbjct: 3829 DSDHAGKWSCVAENDAGVKELEMVLDVF----TPPVVSVKSDNPIKAL----GETITLFC 3880
Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
G P P++ W + G + A+ + + Y C A N G
Sbjct: 3881 NASGNPYPQLKWAKGGSLIFDSPDGARISLKG-ARLDIPHLKKTDVGDYTCQALNAAGTS 3939
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
E S V + P I D+ + + + +G P P++ W NG L +
Sbjct: 3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTP- 3998
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
IT ++ I+I + S YT A N AG+ ++ + V P
Sbjct: 3999 GITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 4045
Score = 194 bits (473), Expect = 6e-49
Identities = 268/1073 (24%), Positives = 421/1073 (39%), Gaps = 82/1073 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
PTF + EG +EC++ P+P I+WL KG +NI ++ D
Sbjct: 3300 PTFETHETTFNIVEGESAKIECKIDGHPKPTISWL-KGGRPFNMDNIILSPRGD------ 3352
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I ++F G YT VA N G++ + + T + + K++ G +I
Sbjct: 3353 TLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGEII 3409
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
L V+GNP PT+TW + + A+P S H TI+ +K V T A I
Sbjct: 3410 LKCPVLGNPTPTVTWKRGD---DAVPNDS---RH--TIVNNYDLKINSVTTEDAGQYSCI 3461
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A A E P F+ + + V E TI + VT P+PSI+W+R ++
Sbjct: 3462 AVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKP 3521
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ + + + DG +I + N D G Y C ASN AG S + I V
Sbjct: 3522 VYLYDRYSISPDGSHITI---NKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKS 3578
Query: 933 HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
++ + +T+ LEC S W N +I+ D R I+ +
Sbjct: 3579 NIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNN-ETFGIENVQ 3637
Query: 991 XXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEV------EI 1040
D G C + + + + + PEF I Q +E D L +I
Sbjct: 3638 VTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDI 3697
Query: 1041 NSETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ DV W +D + + D G RKL I S+ + G Y+CI + + A
Sbjct: 3698 ADQVMDVSWTKDSRALDGDLTDNVDISDDG--RKLTISQASLENAGLYTCIALNRAGEAS 3755
Query: 1100 VTV-VEL--PPEI-ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQ 1153
+ VE+ PP I I+R Q N+ T G ++W K+G E+ +I+
Sbjct: 3756 LEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR 3815
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
+ G Q L+I D D AG++SC + G + +L V P + +++ I
Sbjct: 3816 IVEQG--QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKAL 3872
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
T + + W K S+I D+ IS +K L I + D +YTC
Sbjct: 3873 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQ 3931
Query: 1270 LLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
L+A T++ V V V PP+I + R+ +TL Q P P W +N
Sbjct: 3932 ALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGT 3991
Query: 1327 IIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--S 1382
+ H+ P I S S + I V +D G+Y EN G ++ NV ++ P S
Sbjct: 3992 AL---THSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS 4048
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQ 1441
G ++E + + I C E + ++ ++T V+ +T +I
Sbjct: 4049 NGGTKQVIEGELAVIE-CLVEGYPAPQ---VSWLRNGNRVETGVQ-GVRYVTDGRMLTII 4103
Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
++ S + A NE + + T E V+ KI + T +T L
Sbjct: 4104 EARSLDSGIYLCSATNEAGSAQQAYTLE---VLVSPKIITSTPGV----LTPSSGSKFSL 4156
Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G P P ++W +G +K + + Y+C A ND G
Sbjct: 4157 PCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADT 4216
Query: 1561 TSCVVGIQQKPVITIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
V P I+ S N I G E ++ IE E W KNG L
Sbjct: 4217 LEFPVQTIVAPKISTSGNRYINGSE--GTETVIKCEIES-ESSEFSWSKNGVPLLPSN-- 4271
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
N+ E +I+I + S +Y+ A+N AG ++ + L V P E P
Sbjct: 4272 NLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP 4324
Score = 187 bits (456), Expect = 7e-47
Identities = 248/1061 (23%), Positives = 417/1061 (39%), Gaps = 91/1061 (8%)
Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
G DI L C L + W G E D +V I SD H L IT+ K
Sbjct: 1657 GKDISLSCDLQTESDDKTTFVWSINGSE--SDRPDNVQIPSDGHR----LYITDAKPENN 1710
Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSAQVVGNPR 763
G Y N G+A + L + EPP +EP+ + + +IL QV GNP+
Sbjct: 1711 GKYMCRVTNSAGKAERTLTLDVL----EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPK 1766
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEGIAETSAVITV 822
PT+ W + V KS S+++L+ +K+ + + AEN G A I
Sbjct: 1767 PTVIWKIDGNDVD----KSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFI-- 1820
Query: 823 EEPTEENAEPPLFINRFQEITV-KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
+N P F N + T+ +E TI L V+ ITW + ++ ++ I
Sbjct: 1821 -----QNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWMKQGLPLTENDAI-- 1872
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
F +N L I N + + + Y CVA+N+AG+ S V + V + +K+ + E
Sbjct: 1873 -FTLDNTRLTILNANRDHED-IYTCVANNTAGQVSKDFDVVVQV--LPKIKNAVVTLEIN 1928
Query: 942 EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
EG+ +IL C + T + KW N+ ++ +E + GV KC
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLP----KEAVFVNNNHTVVVNNVTKYHTGVYKC 1984
Query: 1000 IVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWERDG 1053
+ Q T+ V T P F L + E+ + +E + + A + W +G
Sbjct: 1985 YATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNG 2044
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
+ + + G R L+I + D G Y+C + +E+ A T V++PP I+
Sbjct: 2045 KPFLAETDGVQTLAGG--RFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
V + N E+T K + +V W KDG + +Q+ +G Q+ KI +
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEG--QQFKIVHAE 2160
Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIP---DET 1224
+ G Y C N TA ++ + I + + + I +V A L + P D+
Sbjct: 2161 IAHKGSYICMAKNDVGTAEISFDVDIITRPM-IQKGIKNIVTAIKGGALPFKCPIDDDKN 2219
Query: 1225 L--DVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLK 1280
+ W + I+ + E + R L I TE+D+ +Y+C V DA +
Sbjct: 2220 FKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDF 2279
Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KKCKHTKP 1336
V PP I+ D ++ S VTL P+P+ W + + I + P
Sbjct: 2280 KATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIP 2339
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVTILDKPSPPGKPNILEIDS 1394
+ + L I +++ DAG Y +N+ G DV +NV + K G P+ E
Sbjct: 2340 NGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ 2399
Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
+ + P I ++ + + + +++ + + + L+ S ++
Sbjct: 2400 NE-RVVISCPVYARPPAKITWLKAGKPLQSDKFVKT-SANGQKLYLFKLRETDSSKYTCI 2457
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPK 1512
A NE A +KV + + +P+ ++P ++ IT L C G P P
Sbjct: 2458 ATNE-----AGTDKRDFKV---SMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT 2509
Query: 1513 VTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+TW +DG ++ ++ Y CIA N G + + +
Sbjct: 2510 ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIP 2569
Query: 1571 PVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK---EYNITTKEK 1626
PVI E + E + G+ +V W K+G + D + I
Sbjct: 2570 PVIDGERREAVAVIEGFSSELFCDSNSTGV---DVEWQKDGLTINQDTLRGDSFIQIPSS 2626
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+ ++S S +YT N AG + V D PS
Sbjct: 2627 GKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS 2667
Score = 187 bits (456), Expect = 7e-47
Identities = 229/1061 (21%), Positives = 423/1061 (39%), Gaps = 83/1061 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F + K + G + L+C P P I ++ G+ + + + + S
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--------GS 2905
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I N +K EG YT +A N+ G + +++++ PP++ + ++ V+ G+ +
Sbjct: 2906 TLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLL----PPKLSKEWINVEVQAGDPLT 2961
Query: 754 LSAQVVGNPRPTITWCKN-NKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
L + ITW + K + + +S D + I++ +D Y+ A N
Sbjct: 2962 LECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATP-EDADSYSCIAVNDA 3020
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G AE +TV P P +F + F + T+++ R P P I+W+ + +
Sbjct: 3021 GGAEAVFQVTVNTP------PKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGK 3074
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTF 930
I +T + ++ L I N+ G Y CVA N AG++ V I + +V
Sbjct: 3075 PILEMPGVT--YKQGDLSLRIDNIKPN-QEGRYTCVAENKAGRAEQDTYVEISEPPRVVM 3131
Query: 931 VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
+ + EG+ + C+ + W + + + +++Q +
Sbjct: 3132 ASEVMR---VVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTS----DLLQFSTKLSYLHLR 3184
Query: 988 XXXXXDVGVIKCIV--KDQETSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSET 1044
D G CI K E+ T V+ +P I + + + KE + ++ ++
Sbjct: 3185 ETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 1045 AD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102
V W+R+G+ + E+ + L+IRN + DEG+YSCI +E+ TA
Sbjct: 3245 VPYVTWKRNGK---------EIEQFNPV--LHIRNATRADEGKYSCIASNEAGTAVADFL 3293
Query: 1103 --VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
V P T + +G A E ++ + W K G N + + +
Sbjct: 3294 IDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMDN---IILSPR 3350
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTL-RLPEFILVPANTD 1213
L I D G Y+C NS + + +P I+ T+ + P+ + A +
Sbjct: 3351 GDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGE 3407
Query: 1214 AYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
L + + T VTW + + + + T++++ L I T +D +Y+C+ ++
Sbjct: 3408 IILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNY---DLKINSVTTEDAGQYSCIAVN 3464
Query: 1273 --AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
TT EV+ P + Y + +T+ + P P+ W K +
Sbjct: 3465 EAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPV-- 3522
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
+ + SI + +TI K + +D G Y R N G +D+++ + IL P K NI+
Sbjct: 3523 YLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDIDLILKIL-VPPKIDKSNII 3581
Query: 1391 EIDSSSI--NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
+ + I + P + + + +I+ T+ + I+N++
Sbjct: 3582 GNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIK-ETKIQSPTVEKPLKNIT-TEPNEDIE-LTCIF 1505
R+ A N + + + + + PT+++ IT T P + E +
Sbjct: 3642 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
V K + DG + + R Y CIA N GE V
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGR-KLTISQASLENAGLYTCIALNRAGEASLEFKV 3760
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I PVI IS D++ + V ++ + G P P + W KNG ++ +D+ NI E
Sbjct: 3761 EILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE--NIRIVE 3818
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ V++I H+ K++ A N AG +E+ L V+ P
Sbjct: 3819 QGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859
Score = 181 bits (440), Expect = 6e-45
Identities = 248/1089 (22%), Positives = 419/1089 (38%), Gaps = 83/1089 (7%)
Query: 632 IPPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
+PPT K K + E S + L C PEPDI W FK E + ENI+ I +
Sbjct: 2285 VPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITW-FKDGEAIHIENIADIIPNG-E 2342
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748
+ + LKIT +K+ G YT A N G + + + T K E + +S +Q
Sbjct: 2343 LNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYES---QQ 2399
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKA 807
E V++S V P ITW K KP+++ K+ + + + K ++ D YT A
Sbjct: 2400 NERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSANGQKLYLFKLRET-DSSKYTCIA 2458
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G + +++ + + P + R ITV L +P P+ITW
Sbjct: 2459 TNEAGTDKRDFKVSML--VAPSFDEPNIVRR---ITVNSGNPSTLHCPAKGSPSPTITWL 2513
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ I P++ FD +L I+ + D G Y C+A+NS G + + +
Sbjct: 2514 KDGNAIEPNDRYVF-FDAGR-QLQISKTEGS-DQGRYTCIATNSVGSDDLENTLEVIIPP 2570
Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYH-----NKKEISGMDHREIIQEGRX 981
V + +++ EG + L C ++ T V +W N+ + G +I G+
Sbjct: 2571 VIDGER-REAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKK 2629
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEV 1038
D G CIV++ + + P +L + + V V
Sbjct: 2630 MSFLSARKS--DSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANI-QTIVPYYPV 2686
Query: 1039 EIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
EIN S V W D + ++P Y+ G K+ + V G Y+C ++
Sbjct: 2687 EINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV--RSQVEHAGTYTCEAQN 2744
Query: 1094 ESCTAE---VTVVELPPEIITRLQNQKVNKGNKA--TFEIELTKGDALVRWFKDGSEIQF 1148
A + V PP + G+ T E + + V W +Q
Sbjct: 2745 NVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQ- 2803
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLP 1203
+ I ++ L + + LDD G Y C N K ++ +E P +L
Sbjct: 2804 NGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLY 2863
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
IL T P T + + K + ++++ +I TL+I ++ +
Sbjct: 2864 PIILGKRLTLDCSATGTPPPT--ILFMKDGKRLNESDEVDIIGS----TLVIDNPQKEVE 2917
Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
YTC+ + +S + VEV+ PPK+ ++ G +TL + + W
Sbjct: 2918 GRYTCIAENKAGRSEKDMMVEVL-LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW 2976
Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
+ S KS L I + DA Y N+ G A+ VT+ P
Sbjct: 2977 SRQFGKDGQLDMRAQSSSDKS-KLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Query: 1382 SPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
G + EI + + E I +++ + + I ++ K I
Sbjct: 3036 KIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFL-DGKPILEMPGVTYKQ-GDLSLRI 3093
Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
N+K N R+ A N+ + +E Y ++ + P V + +
Sbjct: 3094 DNIKPNQEGRYTCVAENK---AGRAEQDTYVEIS-----EPPRVVMASEVMRVVEGRQTT 3145
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-XYKCIAFNDHGEV 1559
+ C G P+P V W +DG+ + + + Y CIA N GE
Sbjct: 3146 IRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGES 3205
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+T+ V + P I +E+ + K G+ ++V + G P P V W +NG ++E ++
Sbjct: 3206 QTTTDVEVLVPP--RIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIE---QF 3260
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
N V+ I+ R+ KY+ ASN AGT+ + + V+ KP+ +
Sbjct: 3261 N-------PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE 3313
Query: 1680 RESVTIEWK 1688
ES IE K
Sbjct: 3314 GESAKIECK 3322
Score = 180 bits (437), Expect = 1e-44
Identities = 229/1065 (21%), Positives = 423/1065 (39%), Gaps = 85/1065 (7%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP + V EG + C + PEP + WL GE D ++ +
Sbjct: 3126 PPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSD-----LLQFSTKL-- 3178
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S L + GTYT +A N+ GE+ +++ PP++ + + + ++G +
Sbjct: 3179 SYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLV----PPRIEDEERVLQGKEGNTY 3234
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ QV G P P +TW +N K ++ + + ++ DEG Y+ A N G
Sbjct: 3235 MVHCQVTGRPVPYVTWKRNGKEIEQF--------NPVLHIRNATRADEGKYSCIASNEAG 3286
Query: 813 IAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
A +I V +PT E E + E + K+ ++ +P P+I+W +
Sbjct: 3287 TAVADFLIDVFTKPTFETHE--------TTFNIVEGESAKIECKIDGHPKPTISWLKGGR 3338
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
+ + I + G+ + ++ D G Y CVA+NS G S +V + K
Sbjct: 3339 PFN-MDNIILSPRGDTLMILKA---QRFDGGLYTCVATNSYGDSEQDFKVNV-YTKPYID 3393
Query: 932 KHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
+ + ++ + G +IL+C + T + W + I+
Sbjct: 3394 ETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNN---YDLKINSV 3450
Query: 990 XXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEINSE-T 1044
D G CI V + T E I P F+RK + +EV E D ++ + S
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
+ W R G+ ++Y G + I + D G+Y C +E+ T+++ +
Sbjct: 3511 PSISWFR-GDKPVYLYDRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLIL 3567
Query: 1103 -VELPPEI--ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDG 1158
+ +PP+I + N E ++ V W K+G +I ++ ++ +
Sbjct: 3568 KILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS-RVILAQ 3626
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA-------ILTVEEPSINFTLRL--PEFILVP 1209
+ I + + D G Y+C N A +L+ E I+ T E +
Sbjct: 3627 NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTIT 3686
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
L +I D+ +DV+W K ++ D ISD R L I + + ++ YTC
Sbjct: 3687 LTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISD-DGRKLTISQASLENAGLYTC 3745
Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
+ L+ L+ +V P ++D R + ++ + P P+ +W+ N
Sbjct: 3746 IALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNG 3805
Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
K + ++ + I + L I + ++ AG + EN+ G ++EM + + P
Sbjct: 3806 KEVTDDENIR--IVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSV 3863
Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
K N ++ +I + + N + + D+ + + ++ + I +LK
Sbjct: 3864 KSDNPIKALGETITLFCNASGNP-YPQLKWAKGGSLIFDSPDGARI-SLKGARLDIPHLK 3921
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
+ A+N S+AS + + V+ +I ++ + + + L C+
Sbjct: 3922 KTDVGDYTCQALNAAGTSEASVSVD---VLVPPEINRDGIDMSPR---LPAQQSLTLQCL 3975
Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P++ W +G L T T + Y C A N G
Sbjct: 3976 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 4035
Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
V + Q PV ISN KQ + G+ ++ ++EG P P+V W +NGN++E + +
Sbjct: 4036 MYNVDVVQAPV--ISNGGTKQVIE-GELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GV 4091
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ I E + S Y A+N AG++ TL+V P
Sbjct: 4092 RYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 4136
Score = 177 bits (431), Expect = 7e-44
Identities = 270/1198 (22%), Positives = 453/1198 (37%), Gaps = 124/1198 (10%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V +C G P P+I W + ++ + + Y L+I + ED G FTC+A+
Sbjct: 810 VTLQCLAVGIPPPEIEWQKGNVLLATLNNPR--YTQLADGNLLITDAQIEDQGQFTCIAR 867
Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
N G S +T L+V +S +L +PP + +
Sbjct: 868 NTYGQQSQSTTLMVTGLVS---------------------PVLGHVPP-------EEQLI 899
Query: 647 EGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG D+ L C +V P+P I W+ K ++ V +E ++ IE S+L++ E
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWI-KDDKPV-EEGPTIKIEGG----GSLLRLRGGNPKDE 953
Query: 706 GTYTVVAVNREGEASLPI-VLKIKTGE----KEPPQVIEPLKSMI-------------VR 747
G YT +AV+ G ++L I V IK E E V +P S + V
Sbjct: 954 GKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVL 1013
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKD-EGVYTL 805
GE + V G P P ITW + +P+ P D T T++ K K GVYT
Sbjct: 1014 DGEGFAIPCVVSGTPPPIITWYLDGRPI--TPNSRDFTVTADNTLIVRKADKSYSGVYTC 1071
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
+A NS G E I + P+ + + V +P P IT
Sbjct: 1072 QATNSAGDNEQKTTIRI-------MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVIT 1124
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
W + + T+ E+ L I NV +E G + C A N+AG + +T+
Sbjct: 1125 W------LLDDKPFTEGVVNEDGSLTIPNV-NEAHRGTFTCHAQNAAGNDTRTVTLTVHT 1177
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS---HTVSTKWYHNKKEISGMDHREIIQEGRXX 982
++ +K + ++LEC V Y +K S + I ++G
Sbjct: 1178 TPTINAENQEKI--ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG--- 1232
Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
+ GV C V + L T+ E + + + V +EI
Sbjct: 1233 ALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPC 1292
Query: 1043 ETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
V W ++G +K + K+ + G +R I +D G Y+C++ +E+ T
Sbjct: 1293 RATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR---IYEADKNDIGNYNCVVTNEAGT 1349
Query: 1098 AEVTV---VELPPEIITRLQ-NQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152
+++T V+ PP I+ Q N G++ + + A V WF+ G I
Sbjct: 1350 SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG--IAIGTDT 1407
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA---ILTVEEPSINFTLRLPEFIL 1207
+ + L I ++DA Y+C+ N K A + + P I + + +
Sbjct: 1408 KGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESI 1467
Query: 1208 VPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
++ + + ++WY K +I+D + D KR L + K D Y
Sbjct: 1468 KESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD--KRKLHVFKAKITDSGVY 1525
Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV +A +V P +D Y+++ K G +VTL FP P W+V
Sbjct: 1526 KCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVV 1585
Query: 1324 NSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
+ +++ K K ++ + +L V G Y ++ D+++ +++L P
Sbjct: 1586 DGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPI 1645
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
N+ I++ D + + T + + E D + + + + + I +
Sbjct: 1646 VGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPS-DGHRLYITD 1704
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
K ++ ++ N + +E T V++ P E K I P I L
Sbjct: 1705 AKPENNGKYMCRVTNS---AGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNP---IILQ 1758
Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
C G P+P V W DG + + ++ C A N G
Sbjct: 1759 CQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRD 1817
Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNI 1621
IQ T NE ++ E + + ++ W K G L END I
Sbjct: 1818 FF--IQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA---I 1872
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
T + T + I R H YT A+NTAG S + + V P K + V+ EI+
Sbjct: 1873 FTLDNTR-LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP-KIKNAVVTLEIN 1928
Score = 157 bits (380), Expect = 1e-37
Identities = 244/1092 (22%), Positives = 419/1092 (38%), Gaps = 106/1092 (9%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GES 751
+ + +K G YT + N GEA + +PP + + L S ++
Sbjct: 2630 MSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN----DPPSISDELSSANIQTIVPYYP 2685
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
V ++ V G+P P + W ++KP++ A ++G+T I +V+ G YT +A
Sbjct: 2686 VEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV---RSQVEHAGTYTCEA 2742
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITW 866
+N+ G A ++ V PP F +E+ + T+ L + P+ S+ W
Sbjct: 2743 QNNVGKARKDFLVRV-------TAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYW 2795
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ ++E + + IT + L +TN+ + D G Y C A N AG + ++ + +E
Sbjct: 2796 HAHDESVQ-NGVITSKYAANEKTLNVTNIQLD-DEGFYYCTAVNEAGITKKFFKLIV-IE 2852
Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXX 984
F+ QK Y GK + L+C + T + + + K ++ D +II
Sbjct: 2853 TPYFLDQ-QKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII----GSTL 2907
Query: 985 XXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
G CI +++ M+V P+ ++ + EV+ D LE I
Sbjct: 2908 VIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIE 2967
Query: 1042 SETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + W R + K + + KLYI + D YSCI +++ AE
Sbjct: 2968 DTSGVHITWSR--QFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEA 3025
Query: 1101 T---VVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSEIQFSNHIQL 1154
V PP+I + + T EI T+G + WF DG I +
Sbjct: 3026 VFQVTVNTPPKIFGDSFSTTEIVAD-TTLEIPCRTEGIPPPEISWFLDGKPILEMPGV-- 3082
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
T L+I + + G Y+C + G ++ + + EP + E + V
Sbjct: 3083 TYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR--VVMASEVMRVVE 3140
Query: 1211 NTDAYLTVEI---PDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
+ E+ P+ V W K + D +F+ K L +R+ T D Y
Sbjct: 3141 GRQTTIRCEVFGNPEPV--VNWLKDGEPYTSDLLQFS----TKLSYLHLRETTLADGGTY 3194
Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
TC+ + +S T VEV+ PP+I D ER + K G+ + P P W N
Sbjct: 3195 TCIATNKAGESQTTTDVEVL-VPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN 3253
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K I+ + L I+ D G Y N G A + + + KP+
Sbjct: 3254 GK----------EIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPT-- 3301
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI------SVKNITKTQT 1438
E ++ NI G S I ++ T W+ ++ NI +
Sbjct: 3302 -----FETHETTFNIV------EGESAKIECKIDGHPKPTISWLKGGRPFNMDNIILSPR 3350
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNE 1497
L + RF V + ++ + +KV TK T+++ K +
Sbjct: 3351 G-DTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVA---GG 3406
Query: 1498 DIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+I L C G P P VTW R D ++ T N Y CIA N+
Sbjct: 3407 EIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEA 3466
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G + T + KP ++ + + D + + P P + W++ +
Sbjct: 3467 GNLTTHYAAEVIGKPTFVRKGGNLYEVIE-NDTITMDCGVTSRPLPSISWFRGDKPVYLY 3525
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
Y+I+ S I I + K S KY ASN AGTS +++ LK+ P + +I
Sbjct: 3526 DRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGN 3583
Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
++ + TI + P+ G+ K+ D N + ++ ET+ I+ + +
Sbjct: 3584 PLAIVARTIYLECPI--SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1737 YMFRVIAQNPVG 1748
+ A N G
Sbjct: 3642 GRYTCTATNRGG 3653
Score = 155 bits (377), Expect = 2e-37
Identities = 223/1013 (22%), Positives = 380/1013 (37%), Gaps = 81/1013 (7%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L I + K G+Y N G A+ L ++ PP ++ V + S++L
Sbjct: 2063 LHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQV----PPTIVNEGGEYTVIENNSLVL 2118
Query: 755 SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+V G P P +TW K+ +PV K++ S+G I ++ +G Y A+N
Sbjct: 2119 PCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIV---HAEIAHKGSYICMAKNDV 2175
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG---TIKLVARVTRNPVPSITWYR 868
G AE S + + P+ + I KG K +N I W R
Sbjct: 2176 GTAEISFDVDI-------ITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLR 2228
Query: 869 NNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
N + I +E + L I NV +E D G Y C N AG++S + T+ V
Sbjct: 2229 NYQPIDLEAEDARITRLSNDRRLTILNV-TENDEGQYSCRVKNDAGENSFDFKATVLVPP 2287
Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG--RXXX 983
+ K+ E TV L C + W+ + + I + +II G
Sbjct: 2288 TIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ 2347
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRK--LQDFEVKEKDVAILEV 1038
D G C + S V TIP+ + D+E ++ + ++
Sbjct: 2348 LKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC 2407
Query: 1039 EINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
+ + A + W + G KP ++ + + +KLY+ D +Y+CI +E+ T
Sbjct: 2408 PVYARPPAKITWLKAG---KPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGT 2464
Query: 1098 ----AEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147
+V+++ P P I+ R+ VN GN +T KG + W KDG+ I+
Sbjct: 2465 DKRDFKVSMLVAPSFDEPNIVRRI---TVNSGNPSTLHCP-AKGSPSPTITWLKDGNAIE 2520
Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP 1203
N + D +Q L+I + D G Y+C VG+ L V P + R
Sbjct: 2521 -PNDRYVFFDAGRQ-LQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGER-R 2577
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDT---EKFTLISDVKKRTLIIRKCT 1259
E + V + L + +DV W K I +DT + F I K+ +
Sbjct: 2578 EAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFL-SAR 2636
Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFP 1315
+ D YTC++ + A KL V PP I D I+ V + P
Sbjct: 2637 KSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSP 2696
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
P W+ + K ++ + + +L I + + AG Y +NN G A + V
Sbjct: 2697 HPKVYWLFDDKPLEP-DSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLV 2755
Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
+ P + + + + + C E++ + +Y+ + + S
Sbjct: 2756 RVTAPPHFEKEREEVVARVGDTMLLTC--NAESSVPLSSVYWHAHDESVQNGVITSKYAA 2813
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
+ ++ N++ + + AVNE I T +++K+I I++P K
Sbjct: 2814 NEKTLNVTNIQLDDEGFYYCTAVNEAGI-----TKKFFKLI---VIETPYFLDQQKLYPI 2865
Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
+ + L C G P P + + +DGK+L + Y CIA
Sbjct: 2866 ILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAE 2925
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
N G E +V + P +S E I + + GD + IE + W + K
Sbjct: 2926 NKAGRSEKDMMVEVLLPP--KLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGK- 2982
Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ + + S + I + + Y+ A N AG + + V P
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Score = 155 bits (375), Expect = 4e-37
Identities = 250/1241 (20%), Positives = 449/1241 (36%), Gaps = 107/1241 (8%)
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+ +N A F T L + DH T D++ + P
Sbjct: 1866 LTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTL 1925
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
++EG +I+L C P P W F ++ P E + V ++ H + + NV K+
Sbjct: 1926 EINEGEEIILTCDAEGNPTPTAKWDFNQGDL-PKEAVFV---NNNH----TVVVNNVTKY 1977
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y A N+ G+A I + ++T + + E + V S+ L V
Sbjct: 1978 HTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTE--SELTVNLTRSITLECDVDDAIG 2035
Query: 764 PTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
I+W N KP A + T + G I K D G Y N G+A +
Sbjct: 2036 VGISWTVNGKPFLAETDGVQTLAGGRFLHIV---SAKTDDHGSYACTVTNEAGVATKTFN 2092
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+ V+ PP +N E TV E ++ L VT P P +TW ++ + +++
Sbjct: 2093 LFVQ-------VPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSV 2145
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT---FVKHLQK 936
+G+ ++V + G Y C+A N G A ++ DV+ +T K ++
Sbjct: 2146 QVLSEGQQFKIVHAEI---AHKGSYICMAKNDVGT----AEISFDVDIITRPMIQKGIKN 2198
Query: 937 SYETEEGKTVILECQTSHTVSTK----WYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXX 991
+G + +C + K W N + I + I +
Sbjct: 2199 IVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTE 2258
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQD---FEVKEKDVAILEVEINSETA 1045
D G C VK+ K T+ P I +D V+ V +
Sbjct: 2259 NDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEP 2318
Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTSVHDEGEYSCILRDESCTAE---- 1099
D+ W +DGE I +N D G + +L I D G+Y+C + + + E
Sbjct: 2319 DITWFKDGEAIH-IENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVN 2377
Query: 1100 VTVVELPPEIITRLQNQKVNKGN-KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157
V V+ +P + + ++ N + + + A + W K G +Q ++ + +
Sbjct: 2378 VNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSAN 2437
Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCT-AILTVEEPSINFTLRLPEFILVPANT 1212
G QKL ++ D+ +Y+C E G K + + PS + + + N
Sbjct: 2438 G--QKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNP 2495
Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
+ +TW K + IE +++ R L I K DQ YTC+ +
Sbjct: 2496 STLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFD--AGRQLQISKTEGSDQGRYTCIATN 2553
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+ + L+ + P ++D ER + G L D + + EW + I +
Sbjct: 2554 SVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFCDSNS-TGVDVEWQKDGLTINQ 2612
Query: 1331 CKHTKPS---IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
S I S ++ +D+G Y + N G A + + D PS
Sbjct: 2613 DTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS----- 2667
Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN- 1446
+ + SS NI P I VV W+ + ++ L N
Sbjct: 2668 --ISDELSSANIQTIVPY---YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNG 2722
Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTC 1503
+ + V K K+ ++ P EK + + + + LTC
Sbjct: 2723 ETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTC 2782
Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
VP V W+ + ++ T + N Y C A N+ G
Sbjct: 2783 NAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGIT 2842
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+ + + + P ++ +G + G PPP +++ K+G +L E
Sbjct: 2843 KKFFKLIVIETPYFL--DQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEV 2900
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
+I S + I ++ +YT A N AG S ++ ++V P + + + +
Sbjct: 2901 DII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQA 2956
Query: 1680 RESVTIEWKPPLDDGGLELT---KYAIE-------KHEPDNNRWIKVADVDRDVETYCIQ 1729
+ +T+E P D G+ +T ++ + + D ++ + D ++Y
Sbjct: 2957 GDPLTLEC-PIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCI 3015
Query: 1730 KLNE--NCEYMFRVIAQNPVG-FSEALESEPIVIKTALDVP 1767
+N+ E +F+V P F ++ + IV T L++P
Sbjct: 3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIP 3056
Score = 154 bits (374), Expect = 6e-37
Identities = 197/794 (24%), Positives = 327/794 (41%), Gaps = 74/794 (9%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A++ G PT + P V+ + L+C V IP P+I W KG ++ N +
Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQ 843
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
+ L IT+ + +G +T +A N G+ S L + TG P P + +
Sbjct: 844 ----LADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMV-TGLVSPVLGHVPPEEQL 898
Query: 746 VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
+ +G+ + LS VV G P+P+I W K++KPV+ PT S+ L+ KDEG YT
Sbjct: 899 I-EGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYT 957
Query: 805 LKAENSEG----------IAETSAVITVE-----EPTEENAEPP--LFINRFQEITVKEK 847
A + G I + V E +PT + +N ++ E
Sbjct: 958 CIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEG 1017
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKC 906
I V V+ P P ITWY + I+P S T D L++ D SG Y C
Sbjct: 1018 FAIPCV--VSGTPPPIITWYLDGRPITPNSRDFTVTADN---TLIVRKADKSY-SGVYTC 1071
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHN 963
A+NSAG + + TI + + Q S+ + C V T +
Sbjct: 1072 QATNSAGDNEQ--KTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDD 1129
Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020
K G+ + ++G G C ++ +T T+ + T P
Sbjct: 1130 KPFTEGV----VNEDGSLTIPNVNEAHR---GTFTCHAQNAAGNDTRTVTLTVHTTPTIN 1182
Query: 1021 RKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ Q+ + D +LE + V +W +GE I + + + G L ++N
Sbjct: 1183 AENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG---ALVLQNV 1239
Query: 1080 SVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD 1134
+ + G + C + ++S + +TV E P+II+ + V KG T
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHE-KPKIISEVPGVVDVVKGFTIEIPCRATGVP 1298
Query: 1135 ALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAIL 1189
++R W K+G +++ + ++D L+IY+ D +D G Y+C E G S+ T +
Sbjct: 1299 EVIRTWNKNGIDLKMDEK-KFSVD-NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHV 1356
Query: 1190 TVEEPSINF-TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTLISD 1247
V+EP I + + +V + VE VTW+++ I DT+ + + SD
Sbjct: 1357 DVQEPPIILPSTQTNNTAVVGDRVELKCYVE-ASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSD 1304
TL+I+ + +D YTC + K+ L+V V+ P K D + IK
Sbjct: 1416 ---GTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
+L + P P W +N K + K + + D K L + K + TD+G+YK N
Sbjct: 1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDK-RKLHVFKAKITDSGVYKCVARN 1531
Query: 1365 NCGHADVEMNVTIL 1378
G V ++
Sbjct: 1532 AAGEGSKSFQVEVI 1545
Score = 153 bits (372), Expect = 1e-36
Identities = 255/1182 (21%), Positives = 445/1182 (37%), Gaps = 104/1182 (8%)
Query: 523 DGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C V G P+P I W + KP ++ + + L +R P+D G +
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWIKDD---KPVEEGPTIKIEGGGSLLRLRGGNPKDEGKY 956
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
TC+A + AG +ST + V+ E + + E +
Sbjct: 957 TCIAVSPAG--NSTLHINVQLIKKP---EFVYKPEGGIVFKPTISGMDEKHVAVVNS--- 1008
Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
V +G + C + P P I W G I P+ + +D + L +
Sbjct: 1009 THDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSR-DFTVTAD-----NTLIVRKAD 1062
Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
K G YT A N G+ ++I P + S + + + V G+
Sbjct: 1063 KSYSGVYTCQATNSAGDNEQKTTIRI----MNTPMISPGQSSFNMVVDDLFTIPCDVYGD 1118
Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
P+P ITW ++KP DG S+TI + G +T A+N+ G + +T
Sbjct: 1119 PKPVITWLLDDKPFTEGVVNEDG---SLTIPNVNEA-HRGTFTCHAQNAAGNDTRTVTLT 1174
Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
V NAE QE + I L P P W E I S+ I
Sbjct: 1175 VHTTPTINAEN-------QEKIALQNDDIVLECPAKALPPPVRLWTYEGEKID-SQLIPH 1226
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
E+ LV+ NV E ++G + C SN AG+ S +T+ EK + + +
Sbjct: 1227 TI-REDGALVLQNVKLE-NTGVFVCQVSNLAGEDSLSYTLTVH-EKPKIISEVPGVVDVV 1283
Query: 942 EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
+G T+ + C+ + V W N ++ MD ++ + D+G C
Sbjct: 1284 KGFTIEIPCRATGVPEVIRTWNKNGIDLK-MDEKKFSVD-NLGTLRIYEADKNDIGNYNC 1341
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-----SETADVVWERDGE 1054
+V ++ ++ + + E L + V VE+ S A V W R G
Sbjct: 1342 VVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGI 1401
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP---- 1106
I Y E G L I++ SV D Y+C + + AE VTV+ P
Sbjct: 1402 AIGTDTKGYVVESDG---TLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKD 1458
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+++T+ + + + + + + + W+ + + T D K+ KL +
Sbjct: 1459 PDVVTQ---ESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKR-KLHV 1514
Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF-ILVPANTDAYLTVEIPDE 1223
+ + D+G Y C N+ + + E + L ++ V A +T+ P
Sbjct: 1515 FKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS 1574
Query: 1224 TL---DVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
+ W +V+E +K+ TL +D TL + + Y CV +
Sbjct: 1575 GFPVPQINWVVDGTVVEPGKKYKGATLSND--GLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632
Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTK 1335
+ VE+ IV + + G D++L D Q W +N + + +
Sbjct: 1633 DIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQ 1692
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEI 1392
D +T K EN G Y R+ N+ G A+ + + +L+ P P + N I
Sbjct: 1693 IPSDGHRLYITDAKPENN--GKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLI 1750
Query: 1393 DSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
++ I + + + TGN + + ++ ++D + W+ ++++ + I+ L T S +
Sbjct: 1751 GNNPIIL---QCQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLR--IEKL-TGKSAQI 1803
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT-EPNEDIELTCIFGGVPQ 1510
A N+ + + +++ I +PT + T +E I L C +
Sbjct: 1804 SCTAENKA----GTASRDFF----IQNIAAPTFKNEGDQETIFRESETITLDCPV-SLGD 1854
Query: 1511 PKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
++TW + G L A + + Y C+A N G+V V +Q
Sbjct: 1855 FQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQV 1914
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
P I N + + G+E ++T EG P P W N L KE T V
Sbjct: 1915 LP--KIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDFNQGDL--PKEAVFVNNNHTVV 1970
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
+ + + H+ Y A+N G + + + V KP G
Sbjct: 1971 --VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESG 2010
Score = 145 bits (351), Expect = 3e-34
Identities = 245/1099 (22%), Positives = 431/1099 (39%), Gaps = 110/1099 (10%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+PP SK+ V G + LEC + I W + D + + +S
Sbjct: 2941 LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW---SRQFGKDGQLDMRAQSSSDK- 2996
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGE 750
S L I +Y+ +AVN G A + + T PP++ + + +
Sbjct: 2997 -SKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADT 3051
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTH-SITILKPKKVKDEGVYTLKA 807
++ + + G P P I+W + KP+ +P T GD I +KP + EG YT A
Sbjct: 3052 TLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQ---EGRYTCVA 3108
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
EN G AE + + +EPP + + + V E + V NP P + W
Sbjct: 3109 ENKAGRAEQDTYVEI-------SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWL 3161
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ E + S+ + + + L T + D G Y C+A+N AG+S + T DVE
Sbjct: 3162 KDGEPYT-SDLLQFSTKLSYLHLRETTL---ADGGTYTCIATNKAGES----QTTTDVEV 3213
Query: 928 VT--FVKHLQKSYETEEGKTVILECQ-TSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX 983
+ ++ ++ + +EG T ++ CQ T V W N KEI + I+
Sbjct: 3214 LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIRNA---- 3269
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
D G CI ++ + + L+ T P F F + E + A +E +I
Sbjct: 3270 ------TRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKI 3323
Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ + W + G + RG L I D G Y+C+ + +E
Sbjct: 3324 DGHPKPTISWLKGGRPFN--MDNIILSPRGDT--LMILKAQRFDGGLYTCVATNSYGDSE 3379
Query: 1100 ----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLT 1155
V V P T Q K G + + + +K G + N + T
Sbjct: 3380 QDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDA-VPNDSRHT 3438
Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210
I LKI +DAG+YSC E GN + A + +P+ F + V
Sbjct: 3439 IVNNYD-LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPT--FVRKGGNLYEVIE 3495
Query: 1211 NTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
N + + L ++W++ + +++++ D T I K D +Y C
Sbjct: 3496 NDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHIT--INKAKLSDGGKYICR 3553
Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY-----QAFPQPNDEWIV 1323
+ T+ + + + + PPKI ++ I + Y PQP+ W
Sbjct: 3554 ASNEAGTSDIDLILKILVPPKI---DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK 3610
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS- 1382
N I ++ + + + I+ V+ TD G Y N G A + ++ +L P
Sbjct: 3611 NGMDINMTD-SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEF 3669
Query: 1383 --PPGKPNIL-EIDSSSINICWDEPENTGNSTI-IYYVVEYQEID--TTEWISVKNITKT 1436
+P I E D+ ++ E+ + + + + + + +D T+ + + + +
Sbjct: 3670 DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRK 3729
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP- 1495
T Q N+ + A+N A E + +KV +I SP V +N +P
Sbjct: 3730 LTISQASLENAGL-YTCIALNR-----AGEASLEFKV----EILSPPVIDISRN-DVQPQ 3778
Query: 1496 ---NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKC 1550
N+ + C G P P + W ++GK++ + E + C
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 3838
Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
+A ND G E V+ + PV+++ +++ IK +G+ + G P P++ W K
Sbjct: 3839 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA---LGETITLFCNASGNPYPQLKWAKG 3895
Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
G+ L D K + + I LK++ YT +A N AGTS V++ V P
Sbjct: 3896 GS-LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEIN 3954
Query: 1670 EGPVIM--REISRESVTIE 1686
+ M R +++S+T++
Sbjct: 3955 RDGIDMSPRLPAQQSLTLQ 3973
Score = 141 bits (341), Expect = 6e-33
Identities = 241/1190 (20%), Positives = 427/1190 (35%), Gaps = 123/1190 (10%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLV 569
I ++K + K + STV C G P P ITWF+ I + + + N L
Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + DAG +TC A N+AG + ++ P +
Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEK--------------------- 2388
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+GIP + + + +++ C + A P I WL G+ + D+ + + +
Sbjct: 2389 -DGIPSDYESQ-------QNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS-ANGQ 2439
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747
+Y L+ T+ K YT +A N G + + + P ++ + + V
Sbjct: 2440 KLYLFKLRETDSSK-----YTCIATNEAGTDKRDFKVSMLVAPSFDEPNIV---RRITVN 2491
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
G L G+P PTITW K+ ++ D + + D+G YT A
Sbjct: 2492 SGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIA 2551
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
NS G + + V P P + R + + V E + +L V + W
Sbjct: 2552 TNSVGSDDLENTLEVIIP------PVIDGERREAVAVIEGFSSELFCDSNSTGV-DVEWQ 2604
Query: 868 RNNEIISPSETITQNF-----DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
++ I+ +F G+ + + + DSG Y C+ N AG+ AR
Sbjct: 2605 KDGLTINQDTLRGDSFIQIPSSGKKMSFLSAR---KSDSGRYTCIVRNPAGE----ARKL 2657
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVI------LECQTSHTVSTK--WYHNKKEISGMDHRE 974
D V + + +T++ + C S + K W + K + D
Sbjct: 2658 FDF-AVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLE-PDSAA 2715
Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEK 1031
G C ++ + LV P F ++ ++ +
Sbjct: 2716 YELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVG 2775
Query: 1032 DVAILEVEINSET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
D +L S + V W E + + + + + L + N + DEG Y C
Sbjct: 2776 DTMLLTCNAESSVPLSSVYWHAHDESV--QNGVITSKYAANEKTLNVTNIQLDDEGFYYC 2833
Query: 1090 ILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
+E+ ++ V+E P + + + + G + T + T + + KDG
Sbjct: 2834 TAVNEAGITKKFFKLIVIE-TPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204
+ S+ + + L I + + G Y+C N + + + E
Sbjct: 2893 RLNESDEVDII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948
Query: 1205 FILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
+I V LT+E P E + +TW ++ + S K + L I + T +
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK-LYIMQATPE 3007
Query: 1262 DQCEYTCVLL-DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPND 1319
D Y+C+ + DA + V PPKI D I + + + + P P
Sbjct: 3008 DADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEI 3067
Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W ++ K I + P + K SL I ++ G Y EN G A+ + V I
Sbjct: 3068 SWFLDGKPILE----MPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEI 3123
Query: 1378 LDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
+ P ++ ++ I E GN + ++ E T++ + T
Sbjct: 3124 SEPPRVVMASEVMRVVEGRQTTI---RCEVFGNPEPVVNWLKDGEPYTSDLLQF----ST 3176
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
+ S +L+ + Y + + S+TT +V + P +E + + +
Sbjct: 3177 KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV-----LVPPRIEDEERVLQGKEG 3231
Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+ C G P P VTW R+GK+++ R Y CIA N+
Sbjct: 3232 NTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIR------NATRADEGKYSCIASNEA 3285
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G ++ + KP T + G+ + I+G P P + W K G D
Sbjct: 3286 GTAVADFLIDVFTKP--TFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMD 3343
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
NI + + I + +R YT A+N+ G S + + VY KP
Sbjct: 3344 ---NIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390
Score = 138 bits (335), Expect = 3e-32
Identities = 248/1116 (22%), Positives = 432/1116 (38%), Gaps = 104/1116 (9%)
Query: 599 IVEAPLSDHGSEMT-VXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLEC 655
I +A ++G M V D+LE PP F + Q + + I+L+C
Sbjct: 1702 ITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE--PPVFVEPVFEANQKLIGNNPIILQC 1759
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P+P + W G ++ + S + + S+L+I + + + A N+
Sbjct: 1760 QVTGNPKPTVIWKIDGNDV----DKSWLFDESL----SLLRIEKLTG-KSAQISCTAENK 1810
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKP 774
G AS ++ P E + I R+ E++ L V +G+ + ITW K P
Sbjct: 1811 AGTASRDFFIQ---NIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ--ITWMKQGLP 1865
Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPP 833
+ D +TIL + E +YT A N+ G +++ V+ P +NA
Sbjct: 1866 LTENDAIFTLDNTRLTILNANR-DHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVT 1924
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
L IN +EI L NP P+ W N + P E + F N +V+
Sbjct: 1925 LEINEGEEII--------LTCDAEGNPTPTAKWDFNQGDL-PKEAV---FVNNNHTVVVN 1972
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVILECQT 952
NV ++ +G YKC A+N G++ V + K F L +S T +++ LEC
Sbjct: 1973 NV-TKYHTGVYKCYATNKVGQAVKTINVHVRT-KPRFESGLTESELTVNLTRSITLECDV 2030
Query: 953 SHT--VSTKWYHNKKE-ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ET 1006
V W N K ++ D + + GR D G C V ++ T
Sbjct: 2031 DDAIGVGISWTVNGKPFLAETDGVQTLAGGR--FLHIVSAKTDDHGSYACTVTNEAGVAT 2088
Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065
T + + P + + ++ V E + +L E+ + VV W +DG +P +
Sbjct: 2089 KTFNLFVQVPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG---RPVGDLKSV 2145
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK-------V 1118
+ ++ I + + +G Y C+ +++ TAE++ +IITR QK
Sbjct: 2146 QVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEIS---FDVDIITRPMIQKGIKNIVTA 2202
Query: 1119 NKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDLDDAG 1174
KG F+ + + W ++ I + ++T ++L I + +D G
Sbjct: 2203 IKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEG 2262
Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETL------- 1225
+YSC V N E S +F T+ +P I++ VE TL
Sbjct: 2263 QYSCRVKND-------AGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGK 2315
Query: 1226 ---DVTWYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-- 1278
D+TW+K IE+ ++ L I + E D +YTC ++ + +
Sbjct: 2316 PEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQD 2375
Query: 1279 LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
+ V V+ P D +Y ++ V + A P W+ K ++ K K S
Sbjct: 2376 VNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS 2435
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSS 1396
+ + L + K+ TD+ Y N G + V++L PS +PNI+ I +S
Sbjct: 2436 ANGQ--KLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPS-FDEPNIVRRITVNS 2492
Query: 1397 IN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
N P S I ++ + I+ + + + Q I + + R+ A
Sbjct: 2493 GNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGR-QLQISKTEGSDQGRYTCIA 2551
Query: 1456 VNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
N V D T E VI + ++ V ++ ++E D T + + +
Sbjct: 2552 TNSVGSDDLENTLEVIIPPVIDGERREAVAV---IEGFSSELFCDSNSTGVDVEWQKDGL 2608
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
T +D + + + Y CI N GE + P I
Sbjct: 2609 TINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSI 2668
Query: 1574 T--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVI 1630
+ +S+ +I Q + V+ G P P+V W + LE D Y +T +T +
Sbjct: 2669 SDELSSANI-QTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET--L 2725
Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+I + H+ YT EA N G + + ++V P
Sbjct: 2726 KIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPP 2761
Score = 132 bits (319), Expect = 3e-30
Identities = 240/1100 (21%), Positives = 415/1100 (37%), Gaps = 121/1100 (11%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
DI+E PP+ P+ Y + + L C + P+P++ W FKG ++ D V +S
Sbjct: 606 DIME--PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDS 663
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
L I + EGTY A+++ G+A L + T PP+V M+V
Sbjct: 664 ------KFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLAT----PPKVEIIQNKMMV 713
Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
+G+ V + + G P P I W KN K + + + I+ K +D G Y+
Sbjct: 714 GRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKD-EDAGAYSC 772
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
EN G A ++V P I + V + + L P P I
Sbjct: 773 VGENMAGKDVQVANLSV-------GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIE 825
Query: 866 WYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W + N +++ + TQ DG L+IT+ E D G + C+A N+ G+ S + +
Sbjct: 826 WQKGNVLLATLNNPRYTQLADG---NLLITDAQIE-DQGQFTCIARNTYGQQSQSTTLMV 881
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGR 980
+ H+ + EG+ + L C + S W + K + + I EG
Sbjct: 882 TGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVE--EGPTIKIEGG 939
Query: 981 XXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD---FE-----VK 1029
D G CI V ST+ + + I PEF+ K + F+ +
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 1030 EKDVAILE---------------VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
EK VA++ V + + W DG I P N DF L
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITP--NSRDFTVTAD-NTL 1056
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132
+R G Y+C + + E T + + + N F I
Sbjct: 1057 IVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVY 1116
Query: 1133 GD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCT 1186
GD ++ W D + F+ + + DG L I + + G ++C GN T
Sbjct: 1117 GDPKPVITWLLD--DKPFTEGV-VNEDG---SLTIPNVNEAHRGTFTCHAQNAAGNDTRT 1170
Query: 1187 AILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV---TW-YKKKSVIEDTEK 1241
LTV P+IN E I + N D + +E P + L W Y+ + +
Sbjct: 1171 VTLTVHTTPTIN--AENQEKIAL-QNDD--IVLECPAKALPPPVRLWTYEGEKIDSQLIP 1225
Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
T+ D L+++ ++ + C + L + + + V E P I + +
Sbjct: 1226 HTIRED---GALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
+G + + P+ W N I K K S+D+ +L I + + D G Y
Sbjct: 1283 VKGFTIEIPCRATGVPEVIRTWNKNG-IDLKMDEKKFSVDN-LGTLRIYEADKNDIGNYN 1340
Query: 1360 LRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYV 1416
+ N G + + +V + + P P + N + + + C+ E + T
Sbjct: 1341 CVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG 1400
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+ DT ++ + T IQ+ + + A N ++A+ ++
Sbjct: 1401 IAI-GTDTKGYVVESDGTLV---IQSASVEDATIYTCKASNPAGKAEAN--------LQV 1448
Query: 1477 TKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYEN 1531
T I SP ++ P + + + + L C P P+++WY + K L KT+ T ++
Sbjct: 1449 TVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD 1508
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----G 1587
+ YKC+A N GE S Q + ++ ++ ++ K K KV G
Sbjct: 1509 KRKLHVFKAKITDSGVYKCVARNAAGEGSKS----FQVEVIVPLNLDESKYKKKVFAKEG 1564
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+E + + G P P++ W +G +E K+Y T + + + Y
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCV 1624
Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666
A + ++V L V P
Sbjct: 1625 AQSKGNILDIDVELSVLAVP 1644
Score = 125 bits (302), Expect = 3e-28
Identities = 172/797 (21%), Positives = 313/797 (39%), Gaps = 68/797 (8%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
I T + PKA G +I+L+C ++ P P + W +G++ VP+++ + +
Sbjct: 3392 IDETIDQTPKAV---AGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN----- 3442
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
LKI +V G Y+ +AVN G + ++ G+ P V + V + ++
Sbjct: 3443 -YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEV-IGK--PTFVRKGGNLYEVIENDT 3498
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+ + V P P+I+W + +KPV S S + K+ D G Y +A N
Sbjct: 3499 ITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEA 3558
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G ++ ++ + P + + I I + TI L ++ P P + W +N
Sbjct: 3559 GTSDIDLILKILVPPK--IDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGM 3613
Query: 872 IISPSET---ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
I+ +++ + QN + IE V D G Y C A+N GK+SH + + +
Sbjct: 3614 DINMTDSRVILAQNNETFGIENV-----QVTDQGRYTCTATNRGGKASHDFSLDV-LSPP 3667
Query: 929 TFVKHLQKSYETEEGKTVILECQ-------TSHTVSTKWYHNKKEISG--MDHREIIQEG 979
F H + EG T+ L C + W + + + G D+ +I +G
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVA 1034
R + G+ CI ++ E S V+ P I R +V
Sbjct: 3728 R--KLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPT 3785
Query: 1035 ILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
I+ + + W ++G+ + +N ++G + ++ +R S H G++SC+ +
Sbjct: 3786 IMRCAVTGHPFPSIKWLKNGKEVTDDEN-IRIVEQGQVLQI-LRTDSDH-AGKWSCVAEN 3842
Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS 1149
++ E+ + V PP + + N G T + ++W K GS I F
Sbjct: 3843 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLI-FD 3901
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPE 1204
+ I K +L I D G+Y+C+ N+ T+ +V P IN +
Sbjct: 3902 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD-GIDM 3960
Query: 1205 FILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+PA L + + + W ++ T T+ SD + I + D
Sbjct: 3961 SPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASD--STFIQINNVSLSD 4018
Query: 1263 QCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ YTC + + L V+VV+ P ++ ++ G + + +P P
Sbjct: 4019 KGVYTCYAENVAGSDNLMYNVDVVQAP--VISNGGTKQVIEGELAVIECLVEGYPAPQVS 4076
Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
W+ N ++ + + LTI + + D+GIY N G A + +L
Sbjct: 4077 WLRNGNRVETGVQGVRYV-TDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 4135
Query: 1381 PS-PPGKPNILEIDSSS 1396
P P +L S S
Sbjct: 4136 PKIITSTPGVLTPSSGS 4152
Score = 118 bits (285), Expect = 3e-26
Identities = 204/945 (21%), Positives = 362/945 (38%), Gaps = 86/945 (9%)
Query: 651 ILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
I LEC + IP+PD+ W G +I + D + +A ++ I NV+ +G YT
Sbjct: 3592 IYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNE------TFGIENVQVTDQGRYT 3645
Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILS-----AQVVGNPR 763
A NR G+AS L + + PP+ I + I R+G+++ L+ A+ + +
Sbjct: 3646 CTATNRGGKASHDFSLDVLS----PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 764 PTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++W K+++ + T + D +TI + +++ G+YT A N G A +
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQAS-LENAGLYTCIALNRAGEASLEFKV 3760
Query: 821 TVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
+ P P + I+R Q + TI A VT +P PSI W +N + ++ E
Sbjct: 3761 EILSP------PVIDISRNDVQPQVAVNQPTIMRCA-VTGHPFPSIKWLKNGKEVTDDEN 3813
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
I G+ ++++ T+ D +G + CVA N AG + +DV V +
Sbjct: 3814 IRIVEQGQVLQILRTDSDH---AGKWSCVAENDAGVKE--LEMVLDVFTPPVVSVKSDNP 3868
Query: 939 ETEEGKTVILECQTSHTV--STKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVG 995
G+T+ L C S KW I D I +G DVG
Sbjct: 3869 IKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKG--ARLDIPHLKKTDVG 3926
Query: 996 VIKC-IVKDQETSTMLVVKETI--PEFIRKLQDFEVK---EKDVAILEVEINSETADVVW 1049
C + TS V + + PE R D + ++ + + + + W
Sbjct: 3927 DYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRW 3986
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL 1105
+G + + I N S+ D+G Y+C + ++ V VV+
Sbjct: 3987 TLNGTALTHSTPGITVASDSTF--IQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQA 4044
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS-NHIQLTIDGKKQKL 1163
P +I+ ++V +G A E + A V W ++G+ ++ ++ DG+ L
Sbjct: 4045 P--VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM--L 4100
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAY-LTVEI 1220
I + D+G Y C N +A T+E + +L P++ + L +
Sbjct: 4101 TIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV 4160
Query: 1221 ---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
PD ++W + I+D E I TL I K E+ Y C +
Sbjct: 4161 RGYPDPI--ISWTLNGNDIKDGENGHTIG--ADGTLHIEKA-EERHLIYECTAKNDAGAD 4215
Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
T + V+ + P R G++ + + ++ W N + +
Sbjct: 4216 TLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLI 4274
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
S D K + ++ +D G Y N G+A + N+ + P +P +
Sbjct: 4275 FSEDYKLIKILSTRL--SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG 4332
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAY 1454
W E I +Y + E+ T + TK ++ I ++ + + +
Sbjct: 4333 DQVTLWCEASGVPQPAITWY--KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCK 4390
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
A N V + E + +I P V N++T P + + L+C G+P+P ++
Sbjct: 4391 AENWV--ASTEEDIDLIVMIP------PEVVPERMNVSTNPRQTVFLSCNATGIPEPVIS 4442
Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGE 1558
W RD Y+ Y CIA +D G+
Sbjct: 4443 WMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ 4487
Score = 115 bits (277), Expect = 3e-25
Identities = 167/808 (20%), Positives = 317/808 (39%), Gaps = 71/808 (8%)
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957
D+G+Y+C ++ G S RV ++ G+ L C T V
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFG--VRNVSVPLGEAAFLHCSTRSAGEVE 550
Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKE 1014
+W + + E + D GV +C+ ++ T M +
Sbjct: 551 IRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608
Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
P QD ++ L E + +V W G + N Y ++ +
Sbjct: 609 EPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLL---NDYKYQVGQDSKF 665
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIEL 1130
LYIR+ + HDEG Y C ++ A T ++ PP++ V +G++ +FE +
Sbjct: 666 LYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKT 725
Query: 1131 TKGDA--LVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
+G +RWFK+G + I+ ++I++ + +L I +DAG YSC VG +
Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKIN----EGQLHIMGAKDEDAGAYSC-VGENMAGK 780
Query: 1188 ILTVEEPSINFTLRLPEFILVP----ANTDAYLTVE---IPDETLDVTWYKKKSVIE--D 1238
+ V S+ R+P I P N + +T++ + ++ W K ++ +
Sbjct: 781 DVQVANLSVG---RVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLN 837
Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIVDY 1293
++T ++D L+I +DQ ++TC+ + ++STT + +V P +
Sbjct: 838 NPRYTQLAD---GNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS--PVLGHV 892
Query: 1294 EREYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
E ++ G D+TL V P+P+ WI + K +++ K I+ + L ++
Sbjct: 893 PPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIK--IEGGGSLLRLRGGNP 950
Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKP----SPPG----KPNILEIDSSSINICWDEP 1404
D G Y + G++ + +NV ++ KP P G KP I +D + +
Sbjct: 951 KDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTH 1010
Query: 1405 E-NTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRA---YA-VNE 1458
+ G I VV W + + IT N+ +A Y+ V
Sbjct: 1011 DVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYT 1070
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
++++ E I+ + +P + + ++ + C G P+P +TW D
Sbjct: 1071 CQATNSAGDNEQKTTIR--IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128
Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
K + + C A N G + + + P I N+
Sbjct: 1129 DKPF--TEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ + D+ ++ + +PPP +W G K+ D + T + + ++ +K
Sbjct: 1187 E--KIALQNDDIVLECPAKALPPPVRLWTYEGEKI--DSQLIPHTIREDGALVLQNVKLE 1242
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ + + SN AG S+ TL V++KP
Sbjct: 1243 NTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270
Score = 104 bits (250), Expect = 6e-22
Identities = 120/542 (22%), Positives = 223/542 (41%), Gaps = 36/542 (6%)
Query: 1227 VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
+TWY + + ++ FT+ +D TLI+RK + YTC ++ + K + +
Sbjct: 1032 ITWYLDGRPITPNSRDFTVTAD---NTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
P I + + + T+ D P+P W+++ K + + ++ S
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTE------GVVNEDGS 1142
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
LTI V G + +N G+ + +T+ P+ + N +I + +I + P
Sbjct: 1143 LTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE-NQEKIALQNDDIVLECP 1201
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDI 1461
+ + E ++ID+ + I +QN+K ++ F N E +
Sbjct: 1202 AKALPPPVRLWTYEGEKIDS-QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL 1260
Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
S E K+I E P V +K T IE+ C GVP+ TW ++G
Sbjct: 1261 SYTLTVHEKPKIISEV----PGVVDVVKGFT------IEIPCRATGVPEVIRTWNKNGID 1310
Query: 1522 LKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
LK K + +N Y C+ N+ G + + V +Q+ P+I S +
Sbjct: 1311 LKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQT 1370
Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
VGD + +E PP V W++ G + D + + + T VI+ ++
Sbjct: 1371 -NNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE--D 1427
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-EL 1698
++ YT +ASN AG + + + V P + V+ +E +ES P+ L ++
Sbjct: 1428 ATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQI 1487
Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP 1757
+ Y +K D+ K +D R + + K +++ +A+N G S++ + E
Sbjct: 1488 SWYLNDKPLIDDKTSWKTSDDKRKLHVF---KAKITDSGVYKCVARNAAGEGSKSFQVEV 1544
Query: 1758 IV 1759
IV
Sbjct: 1545 IV 1546
Score = 86.2 bits (204), Expect = 2e-16
Identities = 119/600 (19%), Positives = 229/600 (38%), Gaps = 57/600 (9%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++ G P F ++V G D+ L C + + I W+ GE+I+ ++
Sbjct: 425 VIVGGPRAFMSPIHQEFV--GRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDT- 481
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
SV I + G Y ++ G S+ K + +E P I ++++ V
Sbjct: 482 -----SVWTIPELSLKDAGEYECRVISNNGNYSV----KTRVETRESPPEIFGVRNVSVP 532
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
GE+ L I W + V P T+ + D GVY A
Sbjct: 533 LGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMA 592
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N+ G++ + + EP P Q++ + + L +P P + WY
Sbjct: 593 RNAGGMSTRKMRLDIMEPPSVKVTP-------QDVYFNMREGVNLSCEAMGDPKPEVHWY 645
Query: 868 -RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ +++ + G++ + + + D G Y+C A + AG+ AR T D+
Sbjct: 646 FKGRHLLNDYKYQV----GQDSKFLYIRDATHHDEGTYECRAMSQAGQ----ARDTTDLM 697
Query: 927 KVT--FVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRX 981
T V+ +Q G V EC+T +W+ N K++ D I EG+
Sbjct: 698 LATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ- 756
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKLQDFEVK-EKDVAILE 1037
D G C+ ++ + V + +P I V E+ V +
Sbjct: 757 --LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQC 814
Query: 1038 VEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093
+ + ++ W++ ++ N +Y G+ L I + + D+G+++CI R+
Sbjct: 815 LAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGN---LLITDAQIEDQGQFTCIARNTYG 871
Query: 1094 -ESCTAEVTVVELPPEIITRL-QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149
+S + + V L ++ + +++ +G T + G + W KD ++
Sbjct: 872 QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG 931
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
I+ I+G L++ + D G+Y+C + + L + I + PEF+ P
Sbjct: 932 PTIK--IEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLI----KKPEFVYKP 985
Score = 85.8 bits (203), Expect = 3e-16
Identities = 108/505 (21%), Positives = 186/505 (36%), Gaps = 47/505 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V EG ++EC + P P ++WL G + V +D M L I +
Sbjct: 4055 VIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM----LTIIEARSLD 4109
Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESVILSAQVVGNPR 763
G Y A N G A L++ P++I ++ G L V G P
Sbjct: 4110 SGIYLCSATNEAGSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPD 4165
Query: 764 PTITWCKNNKPVKALPTKSDGDT-HSI----TILKPKKVKDEGVYTLKAENSEGIAETSA 818
P I+W N +K DG+ H+I T+ K + +Y A+N G
Sbjct: 4166 PIISWTLNGNDIK------DGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGAD---- 4215
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
T+E P + P + + + I E GT ++ + +W +N + PS
Sbjct: 4216 --TLEFPVQTIVAPKISTSGNRYINGSE-GTETVIKCEIESESSEFSWSKNGVPLLPSNN 4272
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
+ + D + I+++ T + D G+Y C A+N AG ++ + ++V + ++
Sbjct: 4273 LIFSEDYKLIKILSTRLS---DQGEYSCTAANKAGNATQ--KTNLNVGVAPKIMERPRTQ 4327
Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
+G V L C+ S + WY + + ++ E + GV
Sbjct: 4328 VVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT-KKKSVIFSSISPSQAGV 4386
Query: 997 IKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD 1052
C ++ ST + ++ PE + + + + L V+ W RD
Sbjct: 4387 YTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRD 4446
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEI 1109
I KY L IRN D+G Y CI + ++ T +V P +
Sbjct: 4447 SNIAIQNNEKYQILG----TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGD 1134
+ + KG E + +GD
Sbjct: 4503 PAPIWVECDEKGKPKKTEYMIDRGD 4527
Score = 75.8 bits (178), Expect = 3e-13
Identities = 109/530 (20%), Positives = 199/530 (37%), Gaps = 41/530 (7%)
Query: 1165 IYDCDLDDAGEYSCEV----GN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + L DAGEY C V GN S T + T E P F +R + VP A+L
Sbjct: 486 IPELSLKDAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCS 542
Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276
+++ W + + + + + TL I T D Y C+ +A ST
Sbjct: 543 TRSAGEVEIRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMST 600
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
K++++++E PP + ++ V L + P+P W + + K
Sbjct: 601 RKMRLDIME-PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHL--LNDYKY 657
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
+ S L I+ + D G Y+ R + G A ++ + P N + +
Sbjct: 658 QVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGD 717
Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ + I ++ I ++I I + Q I K + +
Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIK---INEGQLHIMGAKDEDAGAYSCVG 774
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
N + +V + + PT+ + + + L C+ G+P P++ W
Sbjct: 775 ENMAG--------KDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW 826
Query: 1516 YRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQ 1569
+ L T + T + CIA N +G+ T V G+
Sbjct: 827 QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS 886
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
+ + E+ Q + D L V+ G P P ++W K+ +E I + S+
Sbjct: 887 PVLGHVPPEE--QLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGP--TIKIEGGGSL 942
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMR 1676
+R++ KYT A + AG S++ + +++ KP KPEG ++ +
Sbjct: 943 LRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFK 992
Score = 66.1 bits (154), Expect = 3e-10
Identities = 55/236 (23%), Positives = 101/236 (42%), Gaps = 19/236 (8%)
Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
I+ LSD G E + ++ G+ P ++P+ Q V +G + L C
Sbjct: 4284 ILSTRLSDQG-EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 4342
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--RE 716
+P+P I W +K E++ + + E+ SV+ +++ Q G YT A N
Sbjct: 4343 GVPQPAITW-YKDNELLTNTGVD---ETATTKKKSVI-FSSISPSQAGVYTCKAENWVAS 4397
Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
E + +++ I PP+V+ ++ ++V LS G P P I+W +++
Sbjct: 4398 TEEDIDLIVMI------PPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAI 4451
Query: 777 ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
K G T +I + P D+G Y A++ G + + V +P++ A
Sbjct: 4452 QNNEKYQILGTTLAIRNVLP---DDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPA 4504
Score = 64.1 bits (149), Expect = 1e-09
Identities = 125/609 (20%), Positives = 232/609 (38%), Gaps = 70/609 (11%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G+ +C++E + +W + + PS + ++ +D + ++ + D G ++
Sbjct: 4241 EGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNL-IFSEDYKLIKILSTRL--SDQGEYS 4296
Query: 583 CVAKNAAGFASSTTEL-------IVEAPLSD---HGSEMTVXXXXX-----XXXXXXXAD 627
C A N AG A+ T L I+E P + G ++T+ +
Sbjct: 4297 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 4356
Query: 628 IL--EGIPPTFSKKPKA---QYVDEGSDILLECRL---VAIPEPDIAWLFK-GEEIVPDE 678
+L G+ T + K K+ + + C+ VA E DI + E+VP+
Sbjct: 4357 LLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPER 4416
Query: 679 -NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737
N+S + + C+ I + N E L L I+ +
Sbjct: 4417 MNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGF 4476
Query: 738 IEPLKSMIVRQGESVILSAQVVGNP--RPTITW--C-KNNKPVKALPTKSDGDT--HSIT 790
+ G+ + +V P RP W C + KP K GDT +
Sbjct: 4477 YHCIAKS--DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQ 4534
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+L K V+D + A +S + + +A P FI + + T +
Sbjct: 4535 LLPWKDVEDSSLNGSIAYRCMPGPRSSRTVLL------HAAPQ-FIVKPKNTTAAIGAIV 4587
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
+L P P+ITW ++ ++I S+ F+ L +T ++S DSG+Y C+A N
Sbjct: 4588 ELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT-LNSTSDSGEYTCMAQN 4641
Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN----KKE 966
S G S+ A + +D + K S + E +++ W +N K
Sbjct: 4642 SVGSSTVSAFINVDNNILPTPK--PSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 4699
Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRKL 1023
++G+ + G D+ + C V+++ + + E +PE ++ +
Sbjct: 4700 LAGI---HFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPHLTSAFEGVPE-VKTI 4755
Query: 1024 QDFEVKEKDVAILEVEINSE--TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
EV D +L+ E+ S+ T VVW ++ + + Y L + N
Sbjct: 4756 DKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPN----NSLVLLNVEK 4811
Query: 1082 HDEGEYSCI 1090
+DEG Y C+
Sbjct: 4812 YDEGVYKCV 4820
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 31/294 (10%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F KPK G+ + L C P P I W G+ ++ D +A S
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAY--------S 4620
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
LK+T G YT +A N G +++ + + P+ K++ +VI
Sbjct: 4621 HLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV------AVI 4674
Query: 754 LSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
+ +TW N P+ K L + S+ IL +K D +YT K N
Sbjct: 4675 TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITWYRN 869
+ E E + ++ V ++ L VT +P+ + + W +N
Sbjct: 4735 RRHSIPHLTSAFEGVPE--------VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN 4786
Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
++ + + I + N LV+ NV+ + D G YKCVASNS GK+ ++ +
Sbjct: 4787 DQKMLDDDAI---YVLPNNSLVLLNVE-KYDEGVYKCVASNSIGKAFDDTQLNV 4836
Score = 57.6 bits (133), Expect = 9e-08
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 19/271 (7%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
PQ I K+ G V L G P PTITW K+ K ++ + +T+
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL--- 4626
Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
D G YT A+NS G + SA I V+ +P IT E+ + +
Sbjct: 4627 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERN--QAYS 4684
Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
R +TW N + P +F N LVI + S + GD + +
Sbjct: 4685 R-------GLTW-EYNGVPMPKNLAGIHF-MNNGSLVILDT-SSLKEGDLELYTCKVRNR 4734
Query: 915 SSHG-ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDH 972
H +T E V VK + K E G +V+L+C+ TS ++T K + +D
Sbjct: 4735 RRHSIPHLTSAFEGVPEVKTIDK-VEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDD 4793
Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
+ I D GV KC+ +
Sbjct: 4794 -DAIYVLPNNSLVLLNVEKYDEGVYKCVASN 4823
Score = 56.0 bits (129), Expect = 3e-07
Identities = 61/321 (19%), Positives = 120/321 (37%), Gaps = 22/321 (6%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P + P GS L C + P+P I+W G +I EN I +D
Sbjct: 4136 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGEN-GHTIGAD----- 4189
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
L I ++ + Y A N G +L ++ K + +G
Sbjct: 4190 GTLHIEKAEE-RHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING---SEGTET 4245
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ + + + +W KN P+ + + + + ++ D+G Y+ A N G
Sbjct: 4246 VIKCE-IESESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAG 4304
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A + V P + R + V + + L + P P+ITWY++NE+
Sbjct: 4305 NATQKTNLNV-------GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNEL 4357
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
++ + + + + ++ +++ S +G Y C A N + + + + +
Sbjct: 4358 LT-NTGVDETATTKKKSVIFSSI-SPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 4415
Query: 933 HLQKSYETEEGKTVILECQTS 953
+ S T +TV L C +
Sbjct: 4416 RMNVS--TNPRQTVFLSCNAT 4434
Score = 54.8 bits (126), Expect = 6e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 24/347 (6%)
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
TI ++ DAG Y+ R+ +N G+ V+ V + P P I + + S+ + E
Sbjct: 485 TIPELSLKDAGEYECRVISNNGNYSVKTRVETRESP-----PEIFGVRNVSVPL--GEAA 537
Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA-VNEVDISDA 1464
ST VE + T +V N T+ + N + RA A V E +A
Sbjct: 538 FLHCSTRSAGEVEIRW--TRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNA 595
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
+ + ++ ++ P+V+ +++ E + L+C G P+P+V WY G+ L
Sbjct: 596 GGMST--RKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLN 653
Query: 1525 --AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
++ Y+C A + G+ + + + P + I I+
Sbjct: 654 DYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEI----IQN 709
Query: 1583 KHKVGDEWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
K VG V+ I G P P++ W+KNG L +Y K + I K
Sbjct: 710 KMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDY---IKINEGQLHIMGAKDED 766
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
+ Y+ N AG L V P+ E P +R VT++
Sbjct: 767 AGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQ 813
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C N G+ E + + + + PV + QK + ++ + G P P VIW
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+GN + DK + E S++RI++L S++ + A N AGT+S + ++ P+
Sbjct: 1773 IDGNDV--DKSW--LFDESLSLLRIEKL-TGKSAQISCTAENKAGTASRDFFIQNIAAPT 1827
Query: 1668 -KPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
K EG I RES TI P+ G ++T
Sbjct: 1828 FKNEGD--QETIFRESETITLDCPVSLGDFQIT 1858
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
K +G EC VEGYP PQ++W R ++ Y D + T++ E D+
Sbjct: 4053 KQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII--EARSLDS 4110
Query: 579 GTFTCVAKNAAGFASS--TTELIV 600
G + C A N AG A T E++V
Sbjct: 4111 GIYLCSATNEAGSAQQAYTLEVLV 4134
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
PI + + +T G V+ +C VE P +TWFR+ I D + Y + + TL
Sbjct: 1362 PIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAI--GTDTKGYVVESD-GTL 1418
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
VI+ EDA +TC A N AG A + ++ V A
Sbjct: 1419 VIQSASVEDATIYTCKASNPAGKAEANLQVTVIA 1452
Score = 48.0 bits (109), Expect = 7e-05
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ T E S P V +G C+V G P P + W + +P +
Sbjct: 3116 EQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDG---EPYTSDLL 3172
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ ++ L +RE D GT+TC+A N AG + +TT++ V P
Sbjct: 3173 QFST-KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C A N G + + P I + + HK GD+ + G+P P + WY
Sbjct: 4295 YSCTAANKAGNATQKTNLNVGVAPKI-MERPRTQVVHK-GDQVTLWCEASGVPQPAITWY 4352
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
K+ L N T +K SVI + S + YT +A N ++ ++ L V P
Sbjct: 4353 KDNELLTNTGVDETATTKKKSVI-FSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 4410
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T+ +AP +E+ R + G V C+ G P+P ITW++ ++ + +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET--A 4367
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+++ + P AG +TC A+N +LIV P
Sbjct: 4368 TTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIP 4409
Score = 45.2 bits (102), Expect = 5e-04
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 8/92 (8%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F+ K + G+ V+ C G P P ITW + +I+ S+ F++ Y + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-FEIAY-----SHL 4622
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ D+G +TC+A+N+ G SST +
Sbjct: 4623 KVTLNSTSDSGEYTCMAQNSVG--SSTVSAFI 4652
Score = 44.8 bits (101), Expect = 7e-04
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V C+ G P+P++ W+ + + +Q+ D L IR+ D GT+ C A
Sbjct: 628 VNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSK---FLYIRDATHHDEGTYECRAM 684
Query: 587 NAAGFASSTTELIVEAP 603
+ AG A TT+L++ P
Sbjct: 685 SQAGQARDTTDLMLATP 701
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 508 MAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+AP F E +R G+ C +G P P ITW + I+P+ D +++D
Sbjct: 2475 VAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPN-DRYVFFDAGR- 2532
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGF--ASSTTELIV 600
L I + D G +TC+A N+ G +T E+I+
Sbjct: 2533 -QLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVII 2568
Score = 41.1 bits (92), Expect = 0.008
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 25/102 (24%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
+ VF KPT E VE G + + EC+++G+P+P I+W +K +
Sbjct: 3294 IDVFTKPTFETHETTFNIVE---------GESAKIECKIDGHPKPTISW------LKGGR 3338
Query: 555 DFQMYYDDDNVA------TLVIREVFPEDAGTFTCVAKNAAG 590
F M DN+ TL+I + D G +TCVA N+ G
Sbjct: 3339 PFNM----DNIILSPRGDTLMILKAQRFDGGLYTCVATNSYG 3376
Score = 40.3 bits (90), Expect = 0.015
Identities = 95/459 (20%), Positives = 174/459 (37%), Gaps = 45/459 (9%)
Query: 1002 KDQETSTMLVVKETIPE---FIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEII 1056
K Q T L ++ +P+ F + + +K +A ++ +N S+ +W E
Sbjct: 4456 KYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQK-IATRKLIVNKPSDRPAPIWVECDEKG 4514
Query: 1057 KPKKNKYDFEKRGH-------IRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
KPKK +Y ++ + + ++S++ Y C+ S + ++ P+
Sbjct: 4515 KPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPGPRS--SRTVLLHAAPQF 4572
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
I + +N G A E+ + + W KDG I+ S + LK+
Sbjct: 4573 IVKPKNTTAAIG--AIVELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT 4625
Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
D+GEY+C VG+S +A + V+ N L P+ N E
Sbjct: 4626 LNSTSDSGEYTCMAQNSVGSSTVSAFINVD----NNILPTPKPSSNQKNVAVITCYERNQ 4681
Query: 1223 E-TLDVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKL 1279
+ +TW Y + ++ +++ L E D YTC + + + +
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPH 4741
Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
E P++ ++ + G V L D + P +V +K +K
Sbjct: 4742 LTSAFEGVPEVKTIDK-VEVNNGDSVVL--DCEVTSDPLTTHVVWTKNDQKMLDDDAIYV 4798
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
+ SL + VE D G+YK N+ G A + + + + P + + S INI
Sbjct: 4799 LPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP----LTGFEGSGINI 4854
Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D+ N G S+ + E +T I+ + T T T
Sbjct: 4855 --DDSSNAGGSSRREAYKKENEDASTTTITTTSPTTTTT 4891
Score = 39.9 bits (89), Expect = 0.019
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
+ KP KN T +EL C G P P +TW +DGK ++ +K
Sbjct: 4573 IVKP-KNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIA-YSHLKVTLNSTS 4630
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGI 1567
Y C+A N G S + +
Sbjct: 4631 DSGEYTCMAQNSVGSSTVSAFINV 4654
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 11/91 (12%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E + P ++ R +G+T CQV G P P +TW R K + F
Sbjct: 3209 TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNG---KEIEQFN---- 3261
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
L IR D G ++C+A N AG A
Sbjct: 3262 ----PVLHIRNATRADEGKYSCIASNEAGTA 3288
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P ++ +C +G P PQ+ W TA+ + + D + I V D G
Sbjct: 3965 PAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ---INNVSLSDKGV 4021
Query: 581 FTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613
+TC A+N AG + + +V+AP+ +G V
Sbjct: 4022 YTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV 4055
Score = 37.9 bits (84), Expect = 0.078
Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 26/201 (12%)
Query: 408 FEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKG 467
FE V R GDT+ + AE+ ++ V + D S Q+ K+ EK
Sbjct: 2763 FEKEREEVVARVGDTMLLTCN--AESSVPLSSVYW---HAHDESVQNGVITSKYAANEKT 2817
Query: 468 WVPAQYLMDENNY---TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPD 523
+D+ + T + + +K KL V E P ++Q + PI +
Sbjct: 2818 LNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIIL---------- 2867
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + +C G P P I + + + S + + +TLVI E G +TC
Sbjct: 2868 GKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIG-----STLVIDNPQKEVEGRYTC 2922
Query: 584 VAKNAAGFASSTTELIVEAPL 604
+A+N AG S +++VE L
Sbjct: 2923 IAENKAG--RSEKDMMVEVLL 2941
Score = 37.5 bits (83), Expect = 0.10
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDM 688
EG+P K V+ G ++L+C + + P + W ++++ D+ I V +
Sbjct: 4747 EGVPEV--KTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPNNS- 4803
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
L + NV+K+ EG Y VA N G+A L + G+ P
Sbjct: 4804 ------LVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP 4843
Score = 35.9 bits (79), Expect = 0.32
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E +P + +R P G C +I W R A + + +
Sbjct: 512 TRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTER--- 568
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
+ TL I V DAG + C+A+NA G ++ L I+E P
Sbjct: 569 NPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPP 611
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P + W K+G KL D ++ I S +++ S S +YT A N+ G+S+V
Sbjct: 4595 GPPHPTITWAKDG-KLIEDSKFEIA----YSHLKVTLNSTSDSGEYTCMAQNSVGSSTVS 4649
Query: 1658 VTLKV 1662
+ V
Sbjct: 4650 AFINV 4654
Score = 33.9 bits (74), Expect = 1.3
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 523 DGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C EG P P W F Q + K + ++ ++++ T+V+ V G +
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLPKEA----VFVNNNH--TVVVNNVTKYHTGVY 1982
Query: 582 TCVAKNAAGFASSTTELIVEA-PLSDHG---SEMTVXXXXXXXXXXXXADIL-EGIPPTF 636
C A N G A T + V P + G SE+TV D + GI T
Sbjct: 1983 KCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 637 SKKP 640
+ KP
Sbjct: 2043 NGKP 2046
Score = 33.9 bits (74), Expect = 1.3
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+ +++ C+V G P P +TW + + + Q+ + +V E+ G++
Sbjct: 2112 ENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQF-KIVHAEI--AHKGSYI 2168
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
C+AKN G A + ++ I+ P+ G
Sbjct: 2169 CMAKNDVGTAEISFDVDIITRPMIQKG 2195
Score = 33.9 bits (74), Expect = 1.3
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G +V +C+V P + W + K D +Y +N +LV+ V D G +
Sbjct: 4762 NGDSVVLDCEVTSDPLTTHVVWTKNDQ--KMLDDDAIYVLPNN--SLVLLNVEKYDEGVY 4817
Query: 582 TCVAKNAAGFASSTTELIV 600
CVA N+ G A T+L V
Sbjct: 4818 KCVASNSIGKAFDDTQLNV 4836
Score = 32.7 bits (71), Expect = 3.0
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 510 PIFVEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P+FVE + + + + +CQV G P+P + W + S F D++++
Sbjct: 1736 PVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLF-----DESLSL 1790
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593
L I ++ + A +C A+N AG AS
Sbjct: 1791 LRIEKLTGKSA-QISCTAENKAGTAS 1815
Score = 31.5 bits (68), Expect = 6.8
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
TP GS C V GYP P I+W IK ++ D TL I E E
Sbjct: 4147 TPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD---GTLHI-EKAEERHL 4202
Query: 580 TFTCVAKNAAG 590
+ C AKN AG
Sbjct: 4203 IYECTAKNDAG 4213
>Z47070-7|CAA87344.1| 5175|Caenorhabditis elegans Hypothetical protein
F15G9.4a protein.
Length = 5175
Score = 213 bits (520), Expect = 1e-54
Identities = 282/1187 (23%), Positives = 464/1187 (39%), Gaps = 142/1187 (11%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + EC +E ITW RQ K Q + + L I + PEDA +++C
Sbjct: 2957 GDPLTLECPIEDTSGVHITWSRQFG--KDGQLDMRAQSSSDKSKLYIMQATPEDADSYSC 3014
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+A N AG A + ++ V P G + EGIPP
Sbjct: 3015 IAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCR-TEGIPP--------- 3064
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
PE I+W G+ I+ ++ + D+ L+I N+K
Sbjct: 3065 -----------------PE--ISWFLDGKPILEMPGVTYK-QGDLS-----LRIDNIKPN 3099
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
QEG YT VA N+ G A ++I EPP+V+ + M V +G + +V GNP
Sbjct: 3100 QEGRYTCVAENKAGRAEQDTYVEI----SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPE 3155
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
P + W K+ +P + S L+ + D G YT A N G ++T+ + V
Sbjct: 3156 PVVNWLKDGEPYTS-DLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV- 3213
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
PP + + + KE T + +VT PVP +TW RN + I + F
Sbjct: 3214 ------LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-------EQF 3260
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
N L I N + D G Y C+ASN AG + A IDV K TF H + ++ E
Sbjct: 3261 ---NPVLHIRNA-TRADEGKYSCIASNEAGTAV--ADFLIDVFTKPTFETH-ETTFNIVE 3313
Query: 943 GKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
G++ +EC+ H T W + + MD+ II R D G+ C+
Sbjct: 3314 GESAKIECKIDGHPKPTISWLKGGRPFN-MDN--IILSPRGDTLMILKAQRFDGGLYTCV 3370
Query: 1001 V------KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE 1054
+Q+ + K I E I + V ++ + + + T V W+R G+
Sbjct: 3371 ATNSYGDSEQDFKVNVYTKPYIDETIDQTPK-AVAGGEIILKCPVLGNPTPTVTWKR-GD 3428
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEIIT 1111
P +++ ++ I + + D G+YSCI +E+ T V P +
Sbjct: 3429 DAVPNDSRHTIVNNYDLK---INSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR 3485
Query: 1112 RLQN-QKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
+ N +V + + T + +T + WF+ + + ++ DG + I
Sbjct: 3486 KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDG--SHITINKAK 3543
Query: 1170 LDDAGEYSC----EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223
L D G+Y C E G S IL + P I+ + + + + A T YL I
Sbjct: 3544 LSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVART-IYLECPISGIP 3602
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
DV W K I T+ +++ T I DQ YTC + K++ +
Sbjct: 3603 QPDVIWTKNGMDINMTDSRVILAQ-NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 3661
Query: 1282 EVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDE-----WIVNSKIIKKCKHTK 1335
+V+ PP+ + + IKR G +TL + D+ W +S+ +
Sbjct: 3662 DVLS-PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDN 3720
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I LTI + +AG+Y N G A +E V IL SPP +++I +
Sbjct: 3721 VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL---SPP----VIDISRN 3773
Query: 1396 SINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-SVKNITKTQT--------SIQNLKT 1445
+ +P+ N TI+ V + +W+ + K +T + +Q L+T
Sbjct: 3774 DV-----QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRT 3828
Query: 1446 NSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+S + ++ A N+ + + + + + S + P+K + E I L C
Sbjct: 3829 DSDHAGKWSCVAENDAGVKELEMVLDVF----TPPVVSVKSDNPIKAL----GETITLFC 3880
Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
G P P++ W + G + A+ + + Y C A N G
Sbjct: 3881 NASGNPYPQLKWAKGGSLIFDSPDGARISLKG-ARLDIPHLKKTDVGDYTCQALNAAGTS 3939
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
E S V + P I D+ + + + +G P P++ W NG L +
Sbjct: 3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTP- 3998
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
IT ++ I+I + S YT A N AG+ ++ + V P
Sbjct: 3999 GITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 4045
Score = 194 bits (473), Expect = 6e-49
Identities = 268/1073 (24%), Positives = 421/1073 (39%), Gaps = 82/1073 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
PTF + EG +EC++ P+P I+WL KG +NI ++ D
Sbjct: 3300 PTFETHETTFNIVEGESAKIECKIDGHPKPTISWL-KGGRPFNMDNIILSPRGD------ 3352
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I ++F G YT VA N G++ + + T + + K++ G +I
Sbjct: 3353 TLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGEII 3409
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
L V+GNP PT+TW + + A+P S H TI+ +K V T A I
Sbjct: 3410 LKCPVLGNPTPTVTWKRGD---DAVPNDS---RH--TIVNNYDLKINSVTTEDAGQYSCI 3461
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A A E P F+ + + V E TI + VT P+PSI+W+R ++
Sbjct: 3462 AVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKP 3521
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ + + + DG +I + N D G Y C ASN AG S + I V
Sbjct: 3522 VYLYDRYSISPDGSHITI---NKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKS 3578
Query: 933 HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
++ + +T+ LEC S W N +I+ D R I+ +
Sbjct: 3579 NIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNN-ETFGIENVQ 3637
Query: 991 XXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEV------EI 1040
D G C + + + + + PEF I Q +E D L +I
Sbjct: 3638 VTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDI 3697
Query: 1041 NSETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ DV W +D + + D G RKL I S+ + G Y+CI + + A
Sbjct: 3698 ADQVMDVSWTKDSRALDGDLTDNVDISDDG--RKLTISQASLENAGLYTCIALNRAGEAS 3755
Query: 1100 VTV-VEL--PPEI-ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQ 1153
+ VE+ PP I I+R Q N+ T G ++W K+G E+ +I+
Sbjct: 3756 LEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR 3815
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
+ G Q L+I D D AG++SC + G + +L V P + +++ I
Sbjct: 3816 IVEQG--QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKAL 3872
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
T + + W K S+I D+ IS +K L I + D +YTC
Sbjct: 3873 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQ 3931
Query: 1270 LLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
L+A T++ V V V PP+I + R+ +TL Q P P W +N
Sbjct: 3932 ALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGT 3991
Query: 1327 IIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--S 1382
+ H+ P I S S + I V +D G+Y EN G ++ NV ++ P S
Sbjct: 3992 AL---THSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS 4048
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQ 1441
G ++E + + I C E + ++ ++T V+ +T +I
Sbjct: 4049 NGGTKQVIEGELAVIE-CLVEGYPAPQ---VSWLRNGNRVETGVQ-GVRYVTDGRMLTII 4103
Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
++ S + A NE + + T E V+ KI + T +T L
Sbjct: 4104 EARSLDSGIYLCSATNEAGSAQQAYTLE---VLVSPKIITSTPGV----LTPSSGSKFSL 4156
Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G P P ++W +G +K + + Y+C A ND G
Sbjct: 4157 PCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADT 4216
Query: 1561 TSCVVGIQQKPVITIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
V P I+ S N I G E ++ IE E W KNG L
Sbjct: 4217 LEFPVQTIVAPKISTSGNRYINGSE--GTETVIKCEIES-ESSEFSWSKNGVPLLPSN-- 4271
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
N+ E +I+I + S +Y+ A+N AG ++ + L V P E P
Sbjct: 4272 NLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP 4324
Score = 187 bits (456), Expect = 7e-47
Identities = 248/1061 (23%), Positives = 417/1061 (39%), Gaps = 91/1061 (8%)
Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
G DI L C L + W G E D +V I SD H L IT+ K
Sbjct: 1657 GKDISLSCDLQTESDDKTTFVWSINGSE--SDRPDNVQIPSDGHR----LYITDAKPENN 1710
Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSAQVVGNPR 763
G Y N G+A + L + EPP +EP+ + + +IL QV GNP+
Sbjct: 1711 GKYMCRVTNSAGKAERTLTLDVL----EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPK 1766
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEGIAETSAVITV 822
PT+ W + V KS S+++L+ +K+ + + AEN G A I
Sbjct: 1767 PTVIWKIDGNDVD----KSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFI-- 1820
Query: 823 EEPTEENAEPPLFINRFQEITV-KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
+N P F N + T+ +E TI L V+ ITW + ++ ++ I
Sbjct: 1821 -----QNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWMKQGLPLTENDAI-- 1872
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
F +N L I N + + + Y CVA+N+AG+ S V + V + +K+ + E
Sbjct: 1873 -FTLDNTRLTILNANRDHED-IYTCVANNTAGQVSKDFDVVVQV--LPKIKNAVVTLEIN 1928
Query: 942 EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
EG+ +IL C + T + KW N+ ++ +E + GV KC
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLP----KEAVFVNNNHTVVVNNVTKYHTGVYKC 1984
Query: 1000 IVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWERDG 1053
+ Q T+ V T P F L + E+ + +E + + A + W +G
Sbjct: 1985 YATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNG 2044
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
+ + + G R L+I + D G Y+C + +E+ A T V++PP I+
Sbjct: 2045 KPFLAETDGVQTLAGG--RFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
V + N E+T K + +V W KDG + +Q+ +G Q+ KI +
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEG--QQFKIVHAE 2160
Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIP---DET 1224
+ G Y C N TA ++ + I + + + I +V A L + P D+
Sbjct: 2161 IAHKGSYICMAKNDVGTAEISFDVDIITRPM-IQKGIKNIVTAIKGGALPFKCPIDDDKN 2219
Query: 1225 L--DVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLK 1280
+ W + I+ + E + R L I TE+D+ +Y+C V DA +
Sbjct: 2220 FKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDF 2279
Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KKCKHTKP 1336
V PP I+ D ++ S VTL P+P+ W + + I + P
Sbjct: 2280 KATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIP 2339
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVTILDKPSPPGKPNILEIDS 1394
+ + L I +++ DAG Y +N+ G DV +NV + K G P+ E
Sbjct: 2340 NGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ 2399
Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
+ + P I ++ + + + +++ + + + L+ S ++
Sbjct: 2400 NE-RVVISCPVYARPPAKITWLKAGKPLQSDKFVKT-SANGQKLYLFKLRETDSSKYTCI 2457
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPK 1512
A NE A +KV + + +P+ ++P ++ IT L C G P P
Sbjct: 2458 ATNE-----AGTDKRDFKV---SMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT 2509
Query: 1513 VTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+TW +DG ++ ++ Y CIA N G + + +
Sbjct: 2510 ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIP 2569
Query: 1571 PVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK---EYNITTKEK 1626
PVI E + E + G+ +V W K+G + D + I
Sbjct: 2570 PVIDGERREAVAVIEGFSSELFCDSNSTGV---DVEWQKDGLTINQDTLRGDSFIQIPSS 2626
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+ ++S S +YT N AG + V D PS
Sbjct: 2627 GKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS 2667
Score = 187 bits (456), Expect = 7e-47
Identities = 229/1061 (21%), Positives = 423/1061 (39%), Gaps = 83/1061 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F + K + G + L+C P P I ++ G+ + + + + S
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--------GS 2905
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I N +K EG YT +A N+ G + +++++ PP++ + ++ V+ G+ +
Sbjct: 2906 TLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLL----PPKLSKEWINVEVQAGDPLT 2961
Query: 754 LSAQVVGNPRPTITWCKN-NKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
L + ITW + K + + +S D + I++ +D Y+ A N
Sbjct: 2962 LECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATP-EDADSYSCIAVNDA 3020
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G AE +TV P P +F + F + T+++ R P P I+W+ + +
Sbjct: 3021 GGAEAVFQVTVNTP------PKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGK 3074
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTF 930
I +T + ++ L I N+ G Y CVA N AG++ V I + +V
Sbjct: 3075 PILEMPGVT--YKQGDLSLRIDNIKPN-QEGRYTCVAENKAGRAEQDTYVEISEPPRVVM 3131
Query: 931 VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
+ + EG+ + C+ + W + + + +++Q +
Sbjct: 3132 ASEVMR---VVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTS----DLLQFSTKLSYLHLR 3184
Query: 988 XXXXXDVGVIKCIV--KDQETSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSET 1044
D G CI K E+ T V+ +P I + + + KE + ++ ++
Sbjct: 3185 ETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 1045 AD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102
V W+R+G+ + E+ + L+IRN + DEG+YSCI +E+ TA
Sbjct: 3245 VPYVTWKRNGK---------EIEQFNPV--LHIRNATRADEGKYSCIASNEAGTAVADFL 3293
Query: 1103 --VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
V P T + +G A E ++ + W K G N + + +
Sbjct: 3294 IDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMDN---IILSPR 3350
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTL-RLPEFILVPANTD 1213
L I D G Y+C NS + + +P I+ T+ + P+ + A +
Sbjct: 3351 GDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGE 3407
Query: 1214 AYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
L + + T VTW + + + + T++++ L I T +D +Y+C+ ++
Sbjct: 3408 IILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNY---DLKINSVTTEDAGQYSCIAVN 3464
Query: 1273 --AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
TT EV+ P + Y + +T+ + P P+ W K +
Sbjct: 3465 EAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPV-- 3522
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
+ + SI + +TI K + +D G Y R N G +D+++ + IL P K NI+
Sbjct: 3523 YLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDIDLILKIL-VPPKIDKSNII 3581
Query: 1391 EIDSSSI--NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
+ + I + P + + + +I+ T+ + I+N++
Sbjct: 3582 GNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIK-ETKIQSPTVEKPLKNIT-TEPNEDIE-LTCIF 1505
R+ A N + + + + + PT+++ IT T P + E +
Sbjct: 3642 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
V K + DG + + R Y CIA N GE V
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGR-KLTISQASLENAGLYTCIALNRAGEASLEFKV 3760
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I PVI IS D++ + V ++ + G P P + W KNG ++ +D+ NI E
Sbjct: 3761 EILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE--NIRIVE 3818
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ V++I H+ K++ A N AG +E+ L V+ P
Sbjct: 3819 QGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859
Score = 181 bits (440), Expect = 6e-45
Identities = 248/1089 (22%), Positives = 419/1089 (38%), Gaps = 83/1089 (7%)
Query: 632 IPPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
+PPT K K + E S + L C PEPDI W FK E + ENI+ I +
Sbjct: 2285 VPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITW-FKDGEAIHIENIADIIPNG-E 2342
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748
+ + LKIT +K+ G YT A N G + + + T K E + +S +Q
Sbjct: 2343 LNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYES---QQ 2399
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKA 807
E V++S V P ITW K KP+++ K+ + + + K ++ D YT A
Sbjct: 2400 NERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSANGQKLYLFKLRET-DSSKYTCIA 2458
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G + +++ + + P + R ITV L +P P+ITW
Sbjct: 2459 TNEAGTDKRDFKVSML--VAPSFDEPNIVRR---ITVNSGNPSTLHCPAKGSPSPTITWL 2513
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ I P++ FD +L I+ + D G Y C+A+NS G + + +
Sbjct: 2514 KDGNAIEPNDRYVF-FDAGR-QLQISKTEGS-DQGRYTCIATNSVGSDDLENTLEVIIPP 2570
Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYH-----NKKEISGMDHREIIQEGRX 981
V + +++ EG + L C ++ T V +W N+ + G +I G+
Sbjct: 2571 VIDGER-REAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKK 2629
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEV 1038
D G CIV++ + + P +L + + V V
Sbjct: 2630 MSFLSARKS--DSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANI-QTIVPYYPV 2686
Query: 1039 EIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
EIN S V W D + ++P Y+ G K+ + V G Y+C ++
Sbjct: 2687 EINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV--RSQVEHAGTYTCEAQN 2744
Query: 1094 ESCTAE---VTVVELPPEIITRLQNQKVNKGNKA--TFEIELTKGDALVRWFKDGSEIQF 1148
A + V PP + G+ T E + + V W +Q
Sbjct: 2745 NVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQ- 2803
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLP 1203
+ I ++ L + + LDD G Y C N K ++ +E P +L
Sbjct: 2804 NGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLY 2863
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
IL T P T + + K + ++++ +I TL+I ++ +
Sbjct: 2864 PIILGKRLTLDCSATGTPPPT--ILFMKDGKRLNESDEVDIIGS----TLVIDNPQKEVE 2917
Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
YTC+ + +S + VEV+ PPK+ ++ G +TL + + W
Sbjct: 2918 GRYTCIAENKAGRSEKDMMVEVL-LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW 2976
Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
+ S KS L I + DA Y N+ G A+ VT+ P
Sbjct: 2977 SRQFGKDGQLDMRAQSSSDKS-KLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Query: 1382 SPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
G + EI + + E I +++ + + I ++ K I
Sbjct: 3036 KIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFL-DGKPILEMPGVTYKQ-GDLSLRI 3093
Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
N+K N R+ A N+ + +E Y ++ + P V + +
Sbjct: 3094 DNIKPNQEGRYTCVAENK---AGRAEQDTYVEIS-----EPPRVVMASEVMRVVEGRQTT 3145
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-XYKCIAFNDHGEV 1559
+ C G P+P V W +DG+ + + + Y CIA N GE
Sbjct: 3146 IRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGES 3205
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+T+ V + P I +E+ + K G+ ++V + G P P V W +NG ++E ++
Sbjct: 3206 QTTTDVEVLVPP--RIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIE---QF 3260
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
N V+ I+ R+ KY+ ASN AGT+ + + V+ KP+ +
Sbjct: 3261 N-------PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE 3313
Query: 1680 RESVTIEWK 1688
ES IE K
Sbjct: 3314 GESAKIECK 3322
Score = 180 bits (437), Expect = 1e-44
Identities = 229/1065 (21%), Positives = 423/1065 (39%), Gaps = 85/1065 (7%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP + V EG + C + PEP + WL GE D ++ +
Sbjct: 3126 PPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSD-----LLQFSTKL-- 3178
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S L + GTYT +A N+ GE+ +++ PP++ + + + ++G +
Sbjct: 3179 SYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLV----PPRIEDEERVLQGKEGNTY 3234
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ QV G P P +TW +N K ++ + + ++ DEG Y+ A N G
Sbjct: 3235 MVHCQVTGRPVPYVTWKRNGKEIEQF--------NPVLHIRNATRADEGKYSCIASNEAG 3286
Query: 813 IAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
A +I V +PT E E + E + K+ ++ +P P+I+W +
Sbjct: 3287 TAVADFLIDVFTKPTFETHE--------TTFNIVEGESAKIECKIDGHPKPTISWLKGGR 3338
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
+ + I + G+ + ++ D G Y CVA+NS G S +V + K
Sbjct: 3339 PFN-MDNIILSPRGDTLMILKA---QRFDGGLYTCVATNSYGDSEQDFKVNV-YTKPYID 3393
Query: 932 KHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
+ + ++ + G +IL+C + T + W + I+
Sbjct: 3394 ETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNN---YDLKINSV 3450
Query: 990 XXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEINSE-T 1044
D G CI V + T E I P F+RK + +EV E D ++ + S
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
+ W R G+ ++Y G + I + D G+Y C +E+ T+++ +
Sbjct: 3511 PSISWFR-GDKPVYLYDRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLIL 3567
Query: 1103 -VELPPEI--ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDG 1158
+ +PP+I + N E ++ V W K+G +I ++ ++ +
Sbjct: 3568 KILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS-RVILAQ 3626
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA-------ILTVEEPSINFTLRL--PEFILVP 1209
+ I + + D G Y+C N A +L+ E I+ T E +
Sbjct: 3627 NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTIT 3686
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
L +I D+ +DV+W K ++ D ISD R L I + + ++ YTC
Sbjct: 3687 LTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISD-DGRKLTISQASLENAGLYTC 3745
Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
+ L+ L+ +V P ++D R + ++ + P P+ +W+ N
Sbjct: 3746 IALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNG 3805
Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
K + ++ + I + L I + ++ AG + EN+ G ++EM + + P
Sbjct: 3806 KEVTDDENIR--IVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSV 3863
Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
K N ++ +I + + N + + D+ + + ++ + I +LK
Sbjct: 3864 KSDNPIKALGETITLFCNASGNP-YPQLKWAKGGSLIFDSPDGARI-SLKGARLDIPHLK 3921
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
+ A+N S+AS + + V+ +I ++ + + + L C+
Sbjct: 3922 KTDVGDYTCQALNAAGTSEASVSVD---VLVPPEINRDGIDMSPR---LPAQQSLTLQCL 3975
Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P++ W +G L T T + Y C A N G
Sbjct: 3976 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 4035
Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
V + Q PV ISN KQ + G+ ++ ++EG P P+V W +NGN++E + +
Sbjct: 4036 MYNVDVVQAPV--ISNGGTKQVIE-GELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GV 4091
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ I E + S Y A+N AG++ TL+V P
Sbjct: 4092 RYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 4136
Score = 177 bits (431), Expect = 7e-44
Identities = 270/1198 (22%), Positives = 453/1198 (37%), Gaps = 124/1198 (10%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V +C G P P+I W + ++ + + Y L+I + ED G FTC+A+
Sbjct: 810 VTLQCLAVGIPPPEIEWQKGNVLLATLNNPR--YTQLADGNLLITDAQIEDQGQFTCIAR 867
Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
N G S +T L+V +S +L +PP + +
Sbjct: 868 NTYGQQSQSTTLMVTGLVS---------------------PVLGHVPP-------EEQLI 899
Query: 647 EGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG D+ L C +V P+P I W+ K ++ V +E ++ IE S+L++ E
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWI-KDDKPV-EEGPTIKIEGG----GSLLRLRGGNPKDE 953
Query: 706 GTYTVVAVNREGEASLPI-VLKIKTGE----KEPPQVIEPLKSMI-------------VR 747
G YT +AV+ G ++L I V IK E E V +P S + V
Sbjct: 954 GKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVL 1013
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKD-EGVYTL 805
GE + V G P P ITW + +P+ P D T T++ K K GVYT
Sbjct: 1014 DGEGFAIPCVVSGTPPPIITWYLDGRPI--TPNSRDFTVTADNTLIVRKADKSYSGVYTC 1071
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
+A NS G E I + P+ + + V +P P IT
Sbjct: 1072 QATNSAGDNEQKTTIRI-------MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVIT 1124
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
W + + T+ E+ L I NV +E G + C A N+AG + +T+
Sbjct: 1125 W------LLDDKPFTEGVVNEDGSLTIPNV-NEAHRGTFTCHAQNAAGNDTRTVTLTVHT 1177
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS---HTVSTKWYHNKKEISGMDHREIIQEGRXX 982
++ +K + ++LEC V Y +K S + I ++G
Sbjct: 1178 TPTINAENQEKI--ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG--- 1232
Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
+ GV C V + L T+ E + + + V +EI
Sbjct: 1233 ALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPC 1292
Query: 1043 ETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
V W ++G +K + K+ + G +R I +D G Y+C++ +E+ T
Sbjct: 1293 RATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR---IYEADKNDIGNYNCVVTNEAGT 1349
Query: 1098 AEVTV---VELPPEIITRLQ-NQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152
+++T V+ PP I+ Q N G++ + + A V WF+ G I
Sbjct: 1350 SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG--IAIGTDT 1407
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA---ILTVEEPSINFTLRLPEFIL 1207
+ + L I ++DA Y+C+ N K A + + P I + + +
Sbjct: 1408 KGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESI 1467
Query: 1208 VPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
++ + + ++WY K +I+D + D KR L + K D Y
Sbjct: 1468 KESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD--KRKLHVFKAKITDSGVY 1525
Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV +A +V P +D Y+++ K G +VTL FP P W+V
Sbjct: 1526 KCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVV 1585
Query: 1324 NSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
+ +++ K K ++ + +L V G Y ++ D+++ +++L P
Sbjct: 1586 DGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPI 1645
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
N+ I++ D + + T + + E D + + + + + I +
Sbjct: 1646 VGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPS-DGHRLYITD 1704
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
K ++ ++ N + +E T V++ P E K I P I L
Sbjct: 1705 AKPENNGKYMCRVTNS---AGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNP---IILQ 1758
Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
C G P+P V W DG + + ++ C A N G
Sbjct: 1759 CQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRD 1817
Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNI 1621
IQ T NE ++ E + + ++ W K G L END I
Sbjct: 1818 FF--IQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA---I 1872
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
T + T + I R H YT A+NTAG S + + V P K + V+ EI+
Sbjct: 1873 FTLDNTR-LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP-KIKNAVVTLEIN 1928
Score = 157 bits (380), Expect = 1e-37
Identities = 244/1092 (22%), Positives = 419/1092 (38%), Gaps = 106/1092 (9%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GES 751
+ + +K G YT + N GEA + +PP + + L S ++
Sbjct: 2630 MSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN----DPPSISDELSSANIQTIVPYYP 2685
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
V ++ V G+P P + W ++KP++ A ++G+T I +V+ G YT +A
Sbjct: 2686 VEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV---RSQVEHAGTYTCEA 2742
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITW 866
+N+ G A ++ V PP F +E+ + T+ L + P+ S+ W
Sbjct: 2743 QNNVGKARKDFLVRV-------TAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYW 2795
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ ++E + + IT + L +TN+ + D G Y C A N AG + ++ + +E
Sbjct: 2796 HAHDESVQ-NGVITSKYAANEKTLNVTNIQLD-DEGFYYCTAVNEAGITKKFFKLIV-IE 2852
Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXX 984
F+ QK Y GK + L+C + T + + + K ++ D +II
Sbjct: 2853 TPYFLDQ-QKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII----GSTL 2907
Query: 985 XXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
G CI +++ M+V P+ ++ + EV+ D LE I
Sbjct: 2908 VIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIE 2967
Query: 1042 SETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + W R + K + + KLYI + D YSCI +++ AE
Sbjct: 2968 DTSGVHITWSR--QFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEA 3025
Query: 1101 T---VVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSEIQFSNHIQL 1154
V PP+I + + T EI T+G + WF DG I +
Sbjct: 3026 VFQVTVNTPPKIFGDSFSTTEIVAD-TTLEIPCRTEGIPPPEISWFLDGKPILEMPGV-- 3082
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
T L+I + + G Y+C + G ++ + + EP + E + V
Sbjct: 3083 TYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR--VVMASEVMRVVE 3140
Query: 1211 NTDAYLTVEI---PDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
+ E+ P+ V W K + D +F+ K L +R+ T D Y
Sbjct: 3141 GRQTTIRCEVFGNPEPV--VNWLKDGEPYTSDLLQFS----TKLSYLHLRETTLADGGTY 3194
Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
TC+ + +S T VEV+ PP+I D ER + K G+ + P P W N
Sbjct: 3195 TCIATNKAGESQTTTDVEVL-VPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN 3253
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K I+ + L I+ D G Y N G A + + + KP+
Sbjct: 3254 GK----------EIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPT-- 3301
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI------SVKNITKTQT 1438
E ++ NI G S I ++ T W+ ++ NI +
Sbjct: 3302 -----FETHETTFNIV------EGESAKIECKIDGHPKPTISWLKGGRPFNMDNIILSPR 3350
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNE 1497
L + RF V + ++ + +KV TK T+++ K +
Sbjct: 3351 G-DTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVA---GG 3406
Query: 1498 DIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+I L C G P P VTW R D ++ T N Y CIA N+
Sbjct: 3407 EIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEA 3466
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G + T + KP ++ + + D + + P P + W++ +
Sbjct: 3467 GNLTTHYAAEVIGKPTFVRKGGNLYEVIE-NDTITMDCGVTSRPLPSISWFRGDKPVYLY 3525
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
Y+I+ S I I + K S KY ASN AGTS +++ LK+ P + +I
Sbjct: 3526 DRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGN 3583
Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
++ + TI + P+ G+ K+ D N + ++ ET+ I+ + +
Sbjct: 3584 PLAIVARTIYLECPI--SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1737 YMFRVIAQNPVG 1748
+ A N G
Sbjct: 3642 GRYTCTATNRGG 3653
Score = 155 bits (377), Expect = 2e-37
Identities = 223/1013 (22%), Positives = 380/1013 (37%), Gaps = 81/1013 (7%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L I + K G+Y N G A+ L ++ PP ++ V + S++L
Sbjct: 2063 LHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQV----PPTIVNEGGEYTVIENNSLVL 2118
Query: 755 SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+V G P P +TW K+ +PV K++ S+G I ++ +G Y A+N
Sbjct: 2119 PCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIV---HAEIAHKGSYICMAKNDV 2175
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG---TIKLVARVTRNPVPSITWYR 868
G AE S + + P+ + I KG K +N I W R
Sbjct: 2176 GTAEISFDVDI-------ITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLR 2228
Query: 869 NNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
N + I +E + L I NV +E D G Y C N AG++S + T+ V
Sbjct: 2229 NYQPIDLEAEDARITRLSNDRRLTILNV-TENDEGQYSCRVKNDAGENSFDFKATVLVPP 2287
Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG--RXXX 983
+ K+ E TV L C + W+ + + I + +II G
Sbjct: 2288 TIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ 2347
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRK--LQDFEVKEKDVAILEV 1038
D G C + S V TIP+ + D+E ++ + ++
Sbjct: 2348 LKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC 2407
Query: 1039 EINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
+ + A + W + G KP ++ + + +KLY+ D +Y+CI +E+ T
Sbjct: 2408 PVYARPPAKITWLKAG---KPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGT 2464
Query: 1098 ----AEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147
+V+++ P P I+ R+ VN GN +T KG + W KDG+ I+
Sbjct: 2465 DKRDFKVSMLVAPSFDEPNIVRRI---TVNSGNPSTLHCP-AKGSPSPTITWLKDGNAIE 2520
Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP 1203
N + D +Q L+I + D G Y+C VG+ L V P + R
Sbjct: 2521 -PNDRYVFFDAGRQ-LQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGER-R 2577
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDT---EKFTLISDVKKRTLIIRKCT 1259
E + V + L + +DV W K I +DT + F I K+ +
Sbjct: 2578 EAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFL-SAR 2636
Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFP 1315
+ D YTC++ + A KL V PP I D I+ V + P
Sbjct: 2637 KSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSP 2696
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
P W+ + K ++ + + +L I + + AG Y +NN G A + V
Sbjct: 2697 HPKVYWLFDDKPLEP-DSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLV 2755
Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
+ P + + + + + C E++ + +Y+ + + S
Sbjct: 2756 RVTAPPHFEKEREEVVARVGDTMLLTC--NAESSVPLSSVYWHAHDESVQNGVITSKYAA 2813
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
+ ++ N++ + + AVNE I T +++K+I I++P K
Sbjct: 2814 NEKTLNVTNIQLDDEGFYYCTAVNEAGI-----TKKFFKLI---VIETPYFLDQQKLYPI 2865
Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
+ + L C G P P + + +DGK+L + Y CIA
Sbjct: 2866 ILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAE 2925
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
N G E +V + P +S E I + + GD + IE + W + K
Sbjct: 2926 NKAGRSEKDMMVEVLLPP--KLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGK- 2982
Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ + + S + I + + Y+ A N AG + + V P
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Score = 155 bits (375), Expect = 4e-37
Identities = 250/1241 (20%), Positives = 449/1241 (36%), Gaps = 107/1241 (8%)
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+ +N A F T L + DH T D++ + P
Sbjct: 1866 LTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTL 1925
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
++EG +I+L C P P W F ++ P E + V ++ H + + NV K+
Sbjct: 1926 EINEGEEIILTCDAEGNPTPTAKWDFNQGDL-PKEAVFV---NNNH----TVVVNNVTKY 1977
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y A N+ G+A I + ++T + + E + V S+ L V
Sbjct: 1978 HTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTE--SELTVNLTRSITLECDVDDAIG 2035
Query: 764 PTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
I+W N KP A + T + G I K D G Y N G+A +
Sbjct: 2036 VGISWTVNGKPFLAETDGVQTLAGGRFLHIV---SAKTDDHGSYACTVTNEAGVATKTFN 2092
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+ V+ PP +N E TV E ++ L VT P P +TW ++ + +++
Sbjct: 2093 LFVQ-------VPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSV 2145
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT---FVKHLQK 936
+G+ ++V + G Y C+A N G A ++ DV+ +T K ++
Sbjct: 2146 QVLSEGQQFKIVHAEI---AHKGSYICMAKNDVGT----AEISFDVDIITRPMIQKGIKN 2198
Query: 937 SYETEEGKTVILECQTSHTVSTK----WYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXX 991
+G + +C + K W N + I + I +
Sbjct: 2199 IVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTE 2258
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQD---FEVKEKDVAILEVEINSETA 1045
D G C VK+ K T+ P I +D V+ V +
Sbjct: 2259 NDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEP 2318
Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTSVHDEGEYSCILRDESCTAE---- 1099
D+ W +DGE I +N D G + +L I D G+Y+C + + + E
Sbjct: 2319 DITWFKDGEAIH-IENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVN 2377
Query: 1100 VTVVELPPEIITRLQNQKVNKGN-KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157
V V+ +P + + ++ N + + + A + W K G +Q ++ + +
Sbjct: 2378 VNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSAN 2437
Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCT-AILTVEEPSINFTLRLPEFILVPANT 1212
G QKL ++ D+ +Y+C E G K + + PS + + + N
Sbjct: 2438 G--QKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNP 2495
Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
+ +TW K + IE +++ R L I K DQ YTC+ +
Sbjct: 2496 STLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFD--AGRQLQISKTEGSDQGRYTCIATN 2553
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+ + L+ + P ++D ER + G L D + + EW + I +
Sbjct: 2554 SVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFCDSNS-TGVDVEWQKDGLTINQ 2612
Query: 1331 CKHTKPS---IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
S I S ++ +D+G Y + N G A + + D PS
Sbjct: 2613 DTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS----- 2667
Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN- 1446
+ + SS NI P I VV W+ + ++ L N
Sbjct: 2668 --ISDELSSANIQTIVPY---YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNG 2722
Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTC 1503
+ + V K K+ ++ P EK + + + + LTC
Sbjct: 2723 ETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTC 2782
Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
VP V W+ + ++ T + N Y C A N+ G
Sbjct: 2783 NAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGIT 2842
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+ + + + P ++ +G + G PPP +++ K+G +L E
Sbjct: 2843 KKFFKLIVIETPYFL--DQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEV 2900
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
+I S + I ++ +YT A N AG S ++ ++V P + + + +
Sbjct: 2901 DII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQA 2956
Query: 1680 RESVTIEWKPPLDDGGLELT---KYAIE-------KHEPDNNRWIKVADVDRDVETYCIQ 1729
+ +T+E P D G+ +T ++ + + D ++ + D ++Y
Sbjct: 2957 GDPLTLEC-PIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCI 3015
Query: 1730 KLNE--NCEYMFRVIAQNPVG-FSEALESEPIVIKTALDVP 1767
+N+ E +F+V P F ++ + IV T L++P
Sbjct: 3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIP 3056
Score = 154 bits (374), Expect = 6e-37
Identities = 197/794 (24%), Positives = 327/794 (41%), Gaps = 74/794 (9%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A++ G PT + P V+ + L+C V IP P+I W KG ++ N +
Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQ 843
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
+ L IT+ + +G +T +A N G+ S L + TG P P + +
Sbjct: 844 ----LADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMV-TGLVSPVLGHVPPEEQL 898
Query: 746 VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
+ +G+ + LS VV G P+P+I W K++KPV+ PT S+ L+ KDEG YT
Sbjct: 899 I-EGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYT 957
Query: 805 LKAENSEG----------IAETSAVITVE-----EPTEENAEPP--LFINRFQEITVKEK 847
A + G I + V E +PT + +N ++ E
Sbjct: 958 CIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEG 1017
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKC 906
I V V+ P P ITWY + I+P S T D L++ D SG Y C
Sbjct: 1018 FAIPCV--VSGTPPPIITWYLDGRPITPNSRDFTVTADN---TLIVRKADKSY-SGVYTC 1071
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHN 963
A+NSAG + + TI + + Q S+ + C V T +
Sbjct: 1072 QATNSAGDNEQ--KTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDD 1129
Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020
K G+ + ++G G C ++ +T T+ + T P
Sbjct: 1130 KPFTEGV----VNEDGSLTIPNVNEAHR---GTFTCHAQNAAGNDTRTVTLTVHTTPTIN 1182
Query: 1021 RKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ Q+ + D +LE + V +W +GE I + + + G L ++N
Sbjct: 1183 AENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG---ALVLQNV 1239
Query: 1080 SVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD 1134
+ + G + C + ++S + +TV E P+II+ + V KG T
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHE-KPKIISEVPGVVDVVKGFTIEIPCRATGVP 1298
Query: 1135 ALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAIL 1189
++R W K+G +++ + ++D L+IY+ D +D G Y+C E G S+ T +
Sbjct: 1299 EVIRTWNKNGIDLKMDEK-KFSVD-NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHV 1356
Query: 1190 TVEEPSINF-TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTLISD 1247
V+EP I + + +V + VE VTW+++ I DT+ + + SD
Sbjct: 1357 DVQEPPIILPSTQTNNTAVVGDRVELKCYVE-ASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSD 1304
TL+I+ + +D YTC + K+ L+V V+ P K D + IK
Sbjct: 1416 ---GTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
+L + P P W +N K + K + + D K L + K + TD+G+YK N
Sbjct: 1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDK-RKLHVFKAKITDSGVYKCVARN 1531
Query: 1365 NCGHADVEMNVTIL 1378
G V ++
Sbjct: 1532 AAGEGSKSFQVEVI 1545
Score = 153 bits (372), Expect = 1e-36
Identities = 255/1182 (21%), Positives = 445/1182 (37%), Gaps = 104/1182 (8%)
Query: 523 DGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C V G P+P I W + KP ++ + + L +R P+D G +
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWIKDD---KPVEEGPTIKIEGGGSLLRLRGGNPKDEGKY 956
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
TC+A + AG +ST + V+ E + + E +
Sbjct: 957 TCIAVSPAG--NSTLHINVQLIKKP---EFVYKPEGGIVFKPTISGMDEKHVAVVNS--- 1008
Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
V +G + C + P P I W G I P+ + +D + L +
Sbjct: 1009 THDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSR-DFTVTAD-----NTLIVRKAD 1062
Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
K G YT A N G+ ++I P + S + + + V G+
Sbjct: 1063 KSYSGVYTCQATNSAGDNEQKTTIRI----MNTPMISPGQSSFNMVVDDLFTIPCDVYGD 1118
Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
P+P ITW ++KP DG S+TI + G +T A+N+ G + +T
Sbjct: 1119 PKPVITWLLDDKPFTEGVVNEDG---SLTIPNVNEA-HRGTFTCHAQNAAGNDTRTVTLT 1174
Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
V NAE QE + I L P P W E I S+ I
Sbjct: 1175 VHTTPTINAEN-------QEKIALQNDDIVLECPAKALPPPVRLWTYEGEKID-SQLIPH 1226
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
E+ LV+ NV E ++G + C SN AG+ S +T+ EK + + +
Sbjct: 1227 TI-REDGALVLQNVKLE-NTGVFVCQVSNLAGEDSLSYTLTVH-EKPKIISEVPGVVDVV 1283
Query: 942 EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
+G T+ + C+ + V W N ++ MD ++ + D+G C
Sbjct: 1284 KGFTIEIPCRATGVPEVIRTWNKNGIDLK-MDEKKFSVD-NLGTLRIYEADKNDIGNYNC 1341
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-----SETADVVWERDGE 1054
+V ++ ++ + + E L + V VE+ S A V W R G
Sbjct: 1342 VVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGI 1401
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP---- 1106
I Y E G L I++ SV D Y+C + + AE VTV+ P
Sbjct: 1402 AIGTDTKGYVVESDG---TLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKD 1458
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+++T+ + + + + + + + W+ + + T D K+ KL +
Sbjct: 1459 PDVVTQ---ESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKR-KLHV 1514
Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF-ILVPANTDAYLTVEIPDE 1223
+ + D+G Y C N+ + + E + L ++ V A +T+ P
Sbjct: 1515 FKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS 1574
Query: 1224 TL---DVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
+ W +V+E +K+ TL +D TL + + Y CV +
Sbjct: 1575 GFPVPQINWVVDGTVVEPGKKYKGATLSND--GLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632
Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTK 1335
+ VE+ IV + + G D++L D Q W +N + + +
Sbjct: 1633 DIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQ 1692
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEI 1392
D +T K EN G Y R+ N+ G A+ + + +L+ P P + N I
Sbjct: 1693 IPSDGHRLYITDAKPENN--GKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLI 1750
Query: 1393 DSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
++ I + + + TGN + + ++ ++D + W+ ++++ + I+ L T S +
Sbjct: 1751 GNNPIIL---QCQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLR--IEKL-TGKSAQI 1803
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT-EPNEDIELTCIFGGVPQ 1510
A N+ + + +++ I +PT + T +E I L C +
Sbjct: 1804 SCTAENKA----GTASRDFF----IQNIAAPTFKNEGDQETIFRESETITLDCPV-SLGD 1854
Query: 1511 PKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
++TW + G L A + + Y C+A N G+V V +Q
Sbjct: 1855 FQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQV 1914
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
P I N + + G+E ++T EG P P W N L KE T V
Sbjct: 1915 LP--KIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDFNQGDL--PKEAVFVNNNHTVV 1970
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
+ + + H+ Y A+N G + + + V KP G
Sbjct: 1971 --VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESG 2010
Score = 145 bits (351), Expect = 3e-34
Identities = 245/1099 (22%), Positives = 431/1099 (39%), Gaps = 110/1099 (10%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+PP SK+ V G + LEC + I W + D + + +S
Sbjct: 2941 LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW---SRQFGKDGQLDMRAQSSSDK- 2996
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGE 750
S L I +Y+ +AVN G A + + T PP++ + + +
Sbjct: 2997 -SKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADT 3051
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTH-SITILKPKKVKDEGVYTLKA 807
++ + + G P P I+W + KP+ +P T GD I +KP + EG YT A
Sbjct: 3052 TLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQ---EGRYTCVA 3108
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
EN G AE + + +EPP + + + V E + V NP P + W
Sbjct: 3109 ENKAGRAEQDTYVEI-------SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWL 3161
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ E + S+ + + + L T + D G Y C+A+N AG+S + T DVE
Sbjct: 3162 KDGEPYT-SDLLQFSTKLSYLHLRETTL---ADGGTYTCIATNKAGES----QTTTDVEV 3213
Query: 928 VT--FVKHLQKSYETEEGKTVILECQ-TSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX 983
+ ++ ++ + +EG T ++ CQ T V W N KEI + I+
Sbjct: 3214 LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIRNA---- 3269
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
D G CI ++ + + L+ T P F F + E + A +E +I
Sbjct: 3270 ------TRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKI 3323
Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ + W + G + RG L I D G Y+C+ + +E
Sbjct: 3324 DGHPKPTISWLKGGRPFN--MDNIILSPRGDT--LMILKAQRFDGGLYTCVATNSYGDSE 3379
Query: 1100 ----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLT 1155
V V P T Q K G + + + +K G + N + T
Sbjct: 3380 QDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDA-VPNDSRHT 3438
Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210
I LKI +DAG+YSC E GN + A + +P+ F + V
Sbjct: 3439 IVNNYD-LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPT--FVRKGGNLYEVIE 3495
Query: 1211 NTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
N + + L ++W++ + +++++ D T I K D +Y C
Sbjct: 3496 NDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHIT--INKAKLSDGGKYICR 3553
Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY-----QAFPQPNDEWIV 1323
+ T+ + + + + PPKI ++ I + Y PQP+ W
Sbjct: 3554 ASNEAGTSDIDLILKILVPPKI---DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK 3610
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS- 1382
N I ++ + + + I+ V+ TD G Y N G A + ++ +L P
Sbjct: 3611 NGMDINMTD-SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEF 3669
Query: 1383 --PPGKPNIL-EIDSSSINICWDEPENTGNSTI-IYYVVEYQEID--TTEWISVKNITKT 1436
+P I E D+ ++ E+ + + + + + + +D T+ + + + +
Sbjct: 3670 DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRK 3729
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP- 1495
T Q N+ + A+N A E + +KV +I SP V +N +P
Sbjct: 3730 LTISQASLENAGL-YTCIALNR-----AGEASLEFKV----EILSPPVIDISRN-DVQPQ 3778
Query: 1496 ---NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKC 1550
N+ + C G P P + W ++GK++ + E + C
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 3838
Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
+A ND G E V+ + PV+++ +++ IK +G+ + G P P++ W K
Sbjct: 3839 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA---LGETITLFCNASGNPYPQLKWAKG 3895
Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
G+ L D K + + I LK++ YT +A N AGTS V++ V P
Sbjct: 3896 GS-LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEIN 3954
Query: 1670 EGPVIM--REISRESVTIE 1686
+ M R +++S+T++
Sbjct: 3955 RDGIDMSPRLPAQQSLTLQ 3973
Score = 141 bits (341), Expect = 6e-33
Identities = 241/1190 (20%), Positives = 427/1190 (35%), Gaps = 123/1190 (10%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLV 569
I ++K + K + STV C G P P ITWF+ I + + + N L
Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + DAG +TC A N+AG + ++ P +
Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEK--------------------- 2388
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+GIP + + + +++ C + A P I WL G+ + D+ + + +
Sbjct: 2389 -DGIPSDYESQ-------QNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS-ANGQ 2439
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747
+Y L+ T+ K YT +A N G + + + P ++ + + V
Sbjct: 2440 KLYLFKLRETDSSK-----YTCIATNEAGTDKRDFKVSMLVAPSFDEPNIV---RRITVN 2491
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
G L G+P PTITW K+ ++ D + + D+G YT A
Sbjct: 2492 SGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIA 2551
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
NS G + + V P P + R + + V E + +L V + W
Sbjct: 2552 TNSVGSDDLENTLEVIIP------PVIDGERREAVAVIEGFSSELFCDSNSTGV-DVEWQ 2604
Query: 868 RNNEIISPSETITQNF-----DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
++ I+ +F G+ + + + DSG Y C+ N AG+ AR
Sbjct: 2605 KDGLTINQDTLRGDSFIQIPSSGKKMSFLSAR---KSDSGRYTCIVRNPAGE----ARKL 2657
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVI------LECQTSHTVSTK--WYHNKKEISGMDHRE 974
D V + + +T++ + C S + K W + K + D
Sbjct: 2658 FDF-AVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLE-PDSAA 2715
Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEK 1031
G C ++ + LV P F ++ ++ +
Sbjct: 2716 YELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVG 2775
Query: 1032 DVAILEVEINSET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
D +L S + V W E + + + + + L + N + DEG Y C
Sbjct: 2776 DTMLLTCNAESSVPLSSVYWHAHDESV--QNGVITSKYAANEKTLNVTNIQLDDEGFYYC 2833
Query: 1090 ILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
+E+ ++ V+E P + + + + G + T + T + + KDG
Sbjct: 2834 TAVNEAGITKKFFKLIVIE-TPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204
+ S+ + + L I + + G Y+C N + + + E
Sbjct: 2893 RLNESDEVDII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948
Query: 1205 FILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
+I V LT+E P E + +TW ++ + S K + L I + T +
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK-LYIMQATPE 3007
Query: 1262 DQCEYTCVLL-DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPND 1319
D Y+C+ + DA + V PPKI D I + + + + P P
Sbjct: 3008 DADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEI 3067
Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W ++ K I + P + K SL I ++ G Y EN G A+ + V I
Sbjct: 3068 SWFLDGKPILE----MPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEI 3123
Query: 1378 LDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
+ P ++ ++ I E GN + ++ E T++ + T
Sbjct: 3124 SEPPRVVMASEVMRVVEGRQTTI---RCEVFGNPEPVVNWLKDGEPYTSDLLQF----ST 3176
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
+ S +L+ + Y + + S+TT +V + P +E + + +
Sbjct: 3177 KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV-----LVPPRIEDEERVLQGKEG 3231
Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+ C G P P VTW R+GK+++ R Y CIA N+
Sbjct: 3232 NTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIR------NATRADEGKYSCIASNEA 3285
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G ++ + KP T + G+ + I+G P P + W K G D
Sbjct: 3286 GTAVADFLIDVFTKP--TFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMD 3343
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
NI + + I + +R YT A+N+ G S + + VY KP
Sbjct: 3344 ---NIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390
Score = 138 bits (335), Expect = 3e-32
Identities = 248/1116 (22%), Positives = 432/1116 (38%), Gaps = 104/1116 (9%)
Query: 599 IVEAPLSDHGSEMT-VXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLEC 655
I +A ++G M V D+LE PP F + Q + + I+L+C
Sbjct: 1702 ITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE--PPVFVEPVFEANQKLIGNNPIILQC 1759
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P+P + W G ++ + S + + S+L+I + + + A N+
Sbjct: 1760 QVTGNPKPTVIWKIDGNDV----DKSWLFDESL----SLLRIEKLTG-KSAQISCTAENK 1810
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKP 774
G AS ++ P E + I R+ E++ L V +G+ + ITW K P
Sbjct: 1811 AGTASRDFFIQ---NIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ--ITWMKQGLP 1865
Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPP 833
+ D +TIL + E +YT A N+ G +++ V+ P +NA
Sbjct: 1866 LTENDAIFTLDNTRLTILNANR-DHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVT 1924
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
L IN +EI L NP P+ W N + P E + F N +V+
Sbjct: 1925 LEINEGEEII--------LTCDAEGNPTPTAKWDFNQGDL-PKEAV---FVNNNHTVVVN 1972
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVILECQT 952
NV ++ +G YKC A+N G++ V + K F L +S T +++ LEC
Sbjct: 1973 NV-TKYHTGVYKCYATNKVGQAVKTINVHVRT-KPRFESGLTESELTVNLTRSITLECDV 2030
Query: 953 SHT--VSTKWYHNKKE-ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ET 1006
V W N K ++ D + + GR D G C V ++ T
Sbjct: 2031 DDAIGVGISWTVNGKPFLAETDGVQTLAGGR--FLHIVSAKTDDHGSYACTVTNEAGVAT 2088
Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065
T + + P + + ++ V E + +L E+ + VV W +DG +P +
Sbjct: 2089 KTFNLFVQVPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG---RPVGDLKSV 2145
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK-------V 1118
+ ++ I + + +G Y C+ +++ TAE++ +IITR QK
Sbjct: 2146 QVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEIS---FDVDIITRPMIQKGIKNIVTA 2202
Query: 1119 NKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDLDDAG 1174
KG F+ + + W ++ I + ++T ++L I + +D G
Sbjct: 2203 IKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEG 2262
Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETL------- 1225
+YSC V N E S +F T+ +P I++ VE TL
Sbjct: 2263 QYSCRVKND-------AGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGK 2315
Query: 1226 ---DVTWYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-- 1278
D+TW+K IE+ ++ L I + E D +YTC ++ + +
Sbjct: 2316 PEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQD 2375
Query: 1279 LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
+ V V+ P D +Y ++ V + A P W+ K ++ K K S
Sbjct: 2376 VNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS 2435
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSS 1396
+ + L + K+ TD+ Y N G + V++L PS +PNI+ I +S
Sbjct: 2436 ANGQ--KLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPS-FDEPNIVRRITVNS 2492
Query: 1397 IN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
N P S I ++ + I+ + + + Q I + + R+ A
Sbjct: 2493 GNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGR-QLQISKTEGSDQGRYTCIA 2551
Query: 1456 VNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
N V D T E VI + ++ V ++ ++E D T + + +
Sbjct: 2552 TNSVGSDDLENTLEVIIPPVIDGERREAVAV---IEGFSSELFCDSNSTGVDVEWQKDGL 2608
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
T +D + + + Y CI N GE + P I
Sbjct: 2609 TINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSI 2668
Query: 1574 T--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVI 1630
+ +S+ +I Q + V+ G P P+V W + LE D Y +T +T +
Sbjct: 2669 SDELSSANI-QTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET--L 2725
Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+I + H+ YT EA N G + + ++V P
Sbjct: 2726 KIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPP 2761
Score = 132 bits (319), Expect = 3e-30
Identities = 240/1100 (21%), Positives = 415/1100 (37%), Gaps = 121/1100 (11%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
DI+E PP+ P+ Y + + L C + P+P++ W FKG ++ D V +S
Sbjct: 606 DIME--PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDS 663
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
L I + EGTY A+++ G+A L + T PP+V M+V
Sbjct: 664 ------KFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLAT----PPKVEIIQNKMMV 713
Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
+G+ V + + G P P I W KN K + + + I+ K +D G Y+
Sbjct: 714 GRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKD-EDAGAYSC 772
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
EN G A ++V P I + V + + L P P I
Sbjct: 773 VGENMAGKDVQVANLSV-------GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIE 825
Query: 866 WYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W + N +++ + TQ DG L+IT+ E D G + C+A N+ G+ S + +
Sbjct: 826 WQKGNVLLATLNNPRYTQLADG---NLLITDAQIE-DQGQFTCIARNTYGQQSQSTTLMV 881
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGR 980
+ H+ + EG+ + L C + S W + K + + I EG
Sbjct: 882 TGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVE--EGPTIKIEGG 939
Query: 981 XXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD---FE-----VK 1029
D G CI V ST+ + + I PEF+ K + F+ +
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 1030 EKDVAILE---------------VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
EK VA++ V + + W DG I P N DF L
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITP--NSRDFTVTAD-NTL 1056
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132
+R G Y+C + + E T + + + N F I
Sbjct: 1057 IVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVY 1116
Query: 1133 GD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCT 1186
GD ++ W D + F+ + + DG L I + + G ++C GN T
Sbjct: 1117 GDPKPVITWLLD--DKPFTEGV-VNEDG---SLTIPNVNEAHRGTFTCHAQNAAGNDTRT 1170
Query: 1187 AILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV---TW-YKKKSVIEDTEK 1241
LTV P+IN E I + N D + +E P + L W Y+ + +
Sbjct: 1171 VTLTVHTTPTIN--AENQEKIAL-QNDD--IVLECPAKALPPPVRLWTYEGEKIDSQLIP 1225
Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
T+ D L+++ ++ + C + L + + + V E P I + +
Sbjct: 1226 HTIRED---GALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
+G + + P+ W N I K K S+D+ +L I + + D G Y
Sbjct: 1283 VKGFTIEIPCRATGVPEVIRTWNKNG-IDLKMDEKKFSVDN-LGTLRIYEADKNDIGNYN 1340
Query: 1360 LRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYV 1416
+ N G + + +V + + P P + N + + + C+ E + T
Sbjct: 1341 CVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG 1400
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+ DT ++ + T IQ+ + + A N ++A+ ++
Sbjct: 1401 IAI-GTDTKGYVVESDGTLV---IQSASVEDATIYTCKASNPAGKAEAN--------LQV 1448
Query: 1477 TKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYEN 1531
T I SP ++ P + + + + L C P P+++WY + K L KT+ T ++
Sbjct: 1449 TVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD 1508
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----G 1587
+ YKC+A N GE S Q + ++ ++ ++ K K KV G
Sbjct: 1509 KRKLHVFKAKITDSGVYKCVARNAAGEGSKS----FQVEVIVPLNLDESKYKKKVFAKEG 1564
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+E + + G P P++ W +G +E K+Y T + + + Y
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCV 1624
Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666
A + ++V L V P
Sbjct: 1625 AQSKGNILDIDVELSVLAVP 1644
Score = 125 bits (302), Expect = 3e-28
Identities = 172/797 (21%), Positives = 313/797 (39%), Gaps = 68/797 (8%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
I T + PKA G +I+L+C ++ P P + W +G++ VP+++ + +
Sbjct: 3392 IDETIDQTPKAV---AGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN----- 3442
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
LKI +V G Y+ +AVN G + ++ G+ P V + V + ++
Sbjct: 3443 -YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEV-IGK--PTFVRKGGNLYEVIENDT 3498
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+ + V P P+I+W + +KPV S S + K+ D G Y +A N
Sbjct: 3499 ITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEA 3558
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G ++ ++ + P + + I I + TI L ++ P P + W +N
Sbjct: 3559 GTSDIDLILKILVPPK--IDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGM 3613
Query: 872 IISPSET---ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
I+ +++ + QN + IE V D G Y C A+N GK+SH + + +
Sbjct: 3614 DINMTDSRVILAQNNETFGIENV-----QVTDQGRYTCTATNRGGKASHDFSLDV-LSPP 3667
Query: 929 TFVKHLQKSYETEEGKTVILECQ-------TSHTVSTKWYHNKKEISG--MDHREIIQEG 979
F H + EG T+ L C + W + + + G D+ +I +G
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVA 1034
R + G+ CI ++ E S V+ P I R +V
Sbjct: 3728 R--KLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPT 3785
Query: 1035 ILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
I+ + + W ++G+ + +N ++G + ++ +R S H G++SC+ +
Sbjct: 3786 IMRCAVTGHPFPSIKWLKNGKEVTDDEN-IRIVEQGQVLQI-LRTDSDH-AGKWSCVAEN 3842
Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS 1149
++ E+ + V PP + + N G T + ++W K GS I F
Sbjct: 3843 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLI-FD 3901
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPE 1204
+ I K +L I D G+Y+C+ N+ T+ +V P IN +
Sbjct: 3902 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD-GIDM 3960
Query: 1205 FILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+PA L + + + W ++ T T+ SD + I + D
Sbjct: 3961 SPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASD--STFIQINNVSLSD 4018
Query: 1263 QCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ YTC + + L V+VV+ P ++ ++ G + + +P P
Sbjct: 4019 KGVYTCYAENVAGSDNLMYNVDVVQAP--VISNGGTKQVIEGELAVIECLVEGYPAPQVS 4076
Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
W+ N ++ + + LTI + + D+GIY N G A + +L
Sbjct: 4077 WLRNGNRVETGVQGVRYV-TDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 4135
Query: 1381 PS-PPGKPNILEIDSSS 1396
P P +L S S
Sbjct: 4136 PKIITSTPGVLTPSSGS 4152
Score = 118 bits (285), Expect = 3e-26
Identities = 204/945 (21%), Positives = 362/945 (38%), Gaps = 86/945 (9%)
Query: 651 ILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
I LEC + IP+PD+ W G +I + D + +A ++ I NV+ +G YT
Sbjct: 3592 IYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNE------TFGIENVQVTDQGRYT 3645
Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILS-----AQVVGNPR 763
A NR G+AS L + + PP+ I + I R+G+++ L+ A+ + +
Sbjct: 3646 CTATNRGGKASHDFSLDVLS----PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 764 PTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++W K+++ + T + D +TI + +++ G+YT A N G A +
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQAS-LENAGLYTCIALNRAGEASLEFKV 3760
Query: 821 TVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
+ P P + I+R Q + TI A VT +P PSI W +N + ++ E
Sbjct: 3761 EILSP------PVIDISRNDVQPQVAVNQPTIMRCA-VTGHPFPSIKWLKNGKEVTDDEN 3813
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
I G+ ++++ T+ D +G + CVA N AG + +DV V +
Sbjct: 3814 IRIVEQGQVLQILRTDSDH---AGKWSCVAENDAGVKE--LEMVLDVFTPPVVSVKSDNP 3868
Query: 939 ETEEGKTVILECQTSHTV--STKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVG 995
G+T+ L C S KW I D I +G DVG
Sbjct: 3869 IKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKG--ARLDIPHLKKTDVG 3926
Query: 996 VIKC-IVKDQETSTMLVVKETI--PEFIRKLQDFEVK---EKDVAILEVEINSETADVVW 1049
C + TS V + + PE R D + ++ + + + + W
Sbjct: 3927 DYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRW 3986
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL 1105
+G + + I N S+ D+G Y+C + ++ V VV+
Sbjct: 3987 TLNGTALTHSTPGITVASDSTF--IQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQA 4044
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS-NHIQLTIDGKKQKL 1163
P +I+ ++V +G A E + A V W ++G+ ++ ++ DG+ L
Sbjct: 4045 P--VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM--L 4100
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAY-LTVEI 1220
I + D+G Y C N +A T+E + +L P++ + L +
Sbjct: 4101 TIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV 4160
Query: 1221 ---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
PD ++W + I+D E I TL I K E+ Y C +
Sbjct: 4161 RGYPDPI--ISWTLNGNDIKDGENGHTIG--ADGTLHIEKA-EERHLIYECTAKNDAGAD 4215
Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
T + V+ + P R G++ + + ++ W N + +
Sbjct: 4216 TLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLI 4274
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
S D K + ++ +D G Y N G+A + N+ + P +P +
Sbjct: 4275 FSEDYKLIKILSTRL--SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG 4332
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAY 1454
W E I +Y + E+ T + TK ++ I ++ + + +
Sbjct: 4333 DQVTLWCEASGVPQPAITWY--KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCK 4390
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
A N V + E + +I P V N++T P + + L+C G+P+P ++
Sbjct: 4391 AENWV--ASTEEDIDLIVMIP------PEVVPERMNVSTNPRQTVFLSCNATGIPEPVIS 4442
Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGE 1558
W RD Y+ Y CIA +D G+
Sbjct: 4443 WMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ 4487
Score = 115 bits (277), Expect = 3e-25
Identities = 167/808 (20%), Positives = 317/808 (39%), Gaps = 71/808 (8%)
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957
D+G+Y+C ++ G S RV ++ G+ L C T V
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFG--VRNVSVPLGEAAFLHCSTRSAGEVE 550
Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKE 1014
+W + + E + D GV +C+ ++ T M +
Sbjct: 551 IRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608
Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
P QD ++ L E + +V W G + N Y ++ +
Sbjct: 609 EPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLL---NDYKYQVGQDSKF 665
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIEL 1130
LYIR+ + HDEG Y C ++ A T ++ PP++ V +G++ +FE +
Sbjct: 666 LYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKT 725
Query: 1131 TKGDA--LVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
+G +RWFK+G + I+ ++I++ + +L I +DAG YSC VG +
Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKIN----EGQLHIMGAKDEDAGAYSC-VGENMAGK 780
Query: 1188 ILTVEEPSINFTLRLPEFILVP----ANTDAYLTVE---IPDETLDVTWYKKKSVIE--D 1238
+ V S+ R+P I P N + +T++ + ++ W K ++ +
Sbjct: 781 DVQVANLSVG---RVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLN 837
Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIVDY 1293
++T ++D L+I +DQ ++TC+ + ++STT + +V P +
Sbjct: 838 NPRYTQLAD---GNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS--PVLGHV 892
Query: 1294 EREYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
E ++ G D+TL V P+P+ WI + K +++ K I+ + L ++
Sbjct: 893 PPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIK--IEGGGSLLRLRGGNP 950
Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKP----SPPG----KPNILEIDSSSINICWDEP 1404
D G Y + G++ + +NV ++ KP P G KP I +D + +
Sbjct: 951 KDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTH 1010
Query: 1405 E-NTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRA---YA-VNE 1458
+ G I VV W + + IT N+ +A Y+ V
Sbjct: 1011 DVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYT 1070
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
++++ E I+ + +P + + ++ + C G P+P +TW D
Sbjct: 1071 CQATNSAGDNEQKTTIR--IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128
Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
K + + C A N G + + + P I N+
Sbjct: 1129 DKPF--TEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ + D+ ++ + +PPP +W G K+ D + T + + ++ +K
Sbjct: 1187 E--KIALQNDDIVLECPAKALPPPVRLWTYEGEKI--DSQLIPHTIREDGALVLQNVKLE 1242
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ + + SN AG S+ TL V++KP
Sbjct: 1243 NTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270
Score = 104 bits (250), Expect = 6e-22
Identities = 120/542 (22%), Positives = 223/542 (41%), Gaps = 36/542 (6%)
Query: 1227 VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
+TWY + + ++ FT+ +D TLI+RK + YTC ++ + K + +
Sbjct: 1032 ITWYLDGRPITPNSRDFTVTAD---NTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
P I + + + T+ D P+P W+++ K + + ++ S
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTE------GVVNEDGS 1142
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
LTI V G + +N G+ + +T+ P+ + N +I + +I + P
Sbjct: 1143 LTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE-NQEKIALQNDDIVLECP 1201
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDI 1461
+ + E ++ID+ + I +QN+K ++ F N E +
Sbjct: 1202 AKALPPPVRLWTYEGEKIDS-QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL 1260
Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
S E K+I E P V +K T IE+ C GVP+ TW ++G
Sbjct: 1261 SYTLTVHEKPKIISEV----PGVVDVVKGFT------IEIPCRATGVPEVIRTWNKNGID 1310
Query: 1522 LKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
LK K + +N Y C+ N+ G + + V +Q+ P+I S +
Sbjct: 1311 LKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQT 1370
Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
VGD + +E PP V W++ G + D + + + T VI+ ++
Sbjct: 1371 -NNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE--D 1427
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-EL 1698
++ YT +ASN AG + + + V P + V+ +E +ES P+ L ++
Sbjct: 1428 ATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQI 1487
Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP 1757
+ Y +K D+ K +D R + + K +++ +A+N G S++ + E
Sbjct: 1488 SWYLNDKPLIDDKTSWKTSDDKRKLHVF---KAKITDSGVYKCVARNAAGEGSKSFQVEV 1544
Query: 1758 IV 1759
IV
Sbjct: 1545 IV 1546
Score = 86.2 bits (204), Expect = 2e-16
Identities = 119/600 (19%), Positives = 229/600 (38%), Gaps = 57/600 (9%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++ G P F ++V G D+ L C + + I W+ GE+I+ ++
Sbjct: 425 VIVGGPRAFMSPIHQEFV--GRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDT- 481
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
SV I + G Y ++ G S+ K + +E P I ++++ V
Sbjct: 482 -----SVWTIPELSLKDAGEYECRVISNNGNYSV----KTRVETRESPPEIFGVRNVSVP 532
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
GE+ L I W + V P T+ + D GVY A
Sbjct: 533 LGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMA 592
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N+ G++ + + EP P Q++ + + L +P P + WY
Sbjct: 593 RNAGGMSTRKMRLDIMEPPSVKVTP-------QDVYFNMREGVNLSCEAMGDPKPEVHWY 645
Query: 868 -RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ +++ + G++ + + + D G Y+C A + AG+ AR T D+
Sbjct: 646 FKGRHLLNDYKYQV----GQDSKFLYIRDATHHDEGTYECRAMSQAGQ----ARDTTDLM 697
Query: 927 KVT--FVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRX 981
T V+ +Q G V EC+T +W+ N K++ D I EG+
Sbjct: 698 LATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ- 756
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKLQDFEVK-EKDVAILE 1037
D G C+ ++ + V + +P I V E+ V +
Sbjct: 757 --LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQC 814
Query: 1038 VEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093
+ + ++ W++ ++ N +Y G+ L I + + D+G+++CI R+
Sbjct: 815 LAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGN---LLITDAQIEDQGQFTCIARNTYG 871
Query: 1094 -ESCTAEVTVVELPPEIITRL-QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149
+S + + V L ++ + +++ +G T + G + W KD ++
Sbjct: 872 QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG 931
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
I+ I+G L++ + D G+Y+C + + L + I + PEF+ P
Sbjct: 932 PTIK--IEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLI----KKPEFVYKP 985
Score = 85.8 bits (203), Expect = 3e-16
Identities = 108/505 (21%), Positives = 186/505 (36%), Gaps = 47/505 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V EG ++EC + P P ++WL G + V +D M L I +
Sbjct: 4055 VIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM----LTIIEARSLD 4109
Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESVILSAQVVGNPR 763
G Y A N G A L++ P++I ++ G L V G P
Sbjct: 4110 SGIYLCSATNEAGSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPD 4165
Query: 764 PTITWCKNNKPVKALPTKSDGDT-HSI----TILKPKKVKDEGVYTLKAENSEGIAETSA 818
P I+W N +K DG+ H+I T+ K + +Y A+N G
Sbjct: 4166 PIISWTLNGNDIK------DGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGAD---- 4215
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
T+E P + P + + + I E GT ++ + +W +N + PS
Sbjct: 4216 --TLEFPVQTIVAPKISTSGNRYINGSE-GTETVIKCEIESESSEFSWSKNGVPLLPSNN 4272
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
+ + D + I+++ T + D G+Y C A+N AG ++ + ++V + ++
Sbjct: 4273 LIFSEDYKLIKILSTRLS---DQGEYSCTAANKAGNATQ--KTNLNVGVAPKIMERPRTQ 4327
Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
+G V L C+ S + WY + + ++ E + GV
Sbjct: 4328 VVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT-KKKSVIFSSISPSQAGV 4386
Query: 997 IKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD 1052
C ++ ST + ++ PE + + + + L V+ W RD
Sbjct: 4387 YTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRD 4446
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEI 1109
I KY L IRN D+G Y CI + ++ T +V P +
Sbjct: 4447 SNIAIQNNEKYQILG----TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGD 1134
+ + KG E + +GD
Sbjct: 4503 PAPIWVECDEKGKPKKTEYMIDRGD 4527
Score = 75.8 bits (178), Expect = 3e-13
Identities = 109/530 (20%), Positives = 199/530 (37%), Gaps = 41/530 (7%)
Query: 1165 IYDCDLDDAGEYSCEV----GN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + L DAGEY C V GN S T + T E P F +R + VP A+L
Sbjct: 486 IPELSLKDAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCS 542
Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276
+++ W + + + + + TL I T D Y C+ +A ST
Sbjct: 543 TRSAGEVEIRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMST 600
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
K++++++E PP + ++ V L + P+P W + + K
Sbjct: 601 RKMRLDIME-PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHL--LNDYKY 657
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
+ S L I+ + D G Y+ R + G A ++ + P N + +
Sbjct: 658 QVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGD 717
Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ + I ++ I ++I I + Q I K + +
Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIK---INEGQLHIMGAKDEDAGAYSCVG 774
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
N + +V + + PT+ + + + L C+ G+P P++ W
Sbjct: 775 ENMAG--------KDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW 826
Query: 1516 YRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQ 1569
+ L T + T + CIA N +G+ T V G+
Sbjct: 827 QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS 886
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
+ + E+ Q + D L V+ G P P ++W K+ +E I + S+
Sbjct: 887 PVLGHVPPEE--QLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGP--TIKIEGGGSL 942
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMR 1676
+R++ KYT A + AG S++ + +++ KP KPEG ++ +
Sbjct: 943 LRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFK 992
Score = 66.1 bits (154), Expect = 3e-10
Identities = 55/236 (23%), Positives = 101/236 (42%), Gaps = 19/236 (8%)
Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
I+ LSD G E + ++ G+ P ++P+ Q V +G + L C
Sbjct: 4284 ILSTRLSDQG-EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 4342
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--RE 716
+P+P I W +K E++ + + E+ SV+ +++ Q G YT A N
Sbjct: 4343 GVPQPAITW-YKDNELLTNTGVD---ETATTKKKSVI-FSSISPSQAGVYTCKAENWVAS 4397
Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
E + +++ I PP+V+ ++ ++V LS G P P I+W +++
Sbjct: 4398 TEEDIDLIVMI------PPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAI 4451
Query: 777 ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
K G T +I + P D+G Y A++ G + + V +P++ A
Sbjct: 4452 QNNEKYQILGTTLAIRNVLP---DDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPA 4504
Score = 64.1 bits (149), Expect = 1e-09
Identities = 125/609 (20%), Positives = 232/609 (38%), Gaps = 70/609 (11%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G+ +C++E + +W + + PS + ++ +D + ++ + D G ++
Sbjct: 4241 EGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNL-IFSEDYKLIKILSTRL--SDQGEYS 4296
Query: 583 CVAKNAAGFASSTTEL-------IVEAPLSD---HGSEMTVXXXXX-----XXXXXXXAD 627
C A N AG A+ T L I+E P + G ++T+ +
Sbjct: 4297 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 4356
Query: 628 IL--EGIPPTFSKKPKA---QYVDEGSDILLECRL---VAIPEPDIAWLFK-GEEIVPDE 678
+L G+ T + K K+ + + C+ VA E DI + E+VP+
Sbjct: 4357 LLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPER 4416
Query: 679 -NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737
N+S + + C+ I + N E L L I+ +
Sbjct: 4417 MNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGF 4476
Query: 738 IEPLKSMIVRQGESVILSAQVVGNP--RPTITW--C-KNNKPVKALPTKSDGDT--HSIT 790
+ G+ + +V P RP W C + KP K GDT +
Sbjct: 4477 YHCIAKS--DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQ 4534
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+L K V+D + A +S + + +A P FI + + T +
Sbjct: 4535 LLPWKDVEDSSLNGSIAYRCMPGPRSSRTVLL------HAAPQ-FIVKPKNTTAAIGAIV 4587
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
+L P P+ITW ++ ++I S+ F+ L +T ++S DSG+Y C+A N
Sbjct: 4588 ELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT-LNSTSDSGEYTCMAQN 4641
Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN----KKE 966
S G S+ A + +D + K S + E +++ W +N K
Sbjct: 4642 SVGSSTVSAFINVDNNILPTPK--PSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 4699
Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRKL 1023
++G+ + G D+ + C V+++ + + E +PE ++ +
Sbjct: 4700 LAGI---HFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPHLTSAFEGVPE-VKTI 4755
Query: 1024 QDFEVKEKDVAILEVEINSE--TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
EV D +L+ E+ S+ T VVW ++ + + Y L + N
Sbjct: 4756 DKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPN----NSLVLLNVEK 4811
Query: 1082 HDEGEYSCI 1090
+DEG Y C+
Sbjct: 4812 YDEGVYKCV 4820
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 31/294 (10%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F KPK G+ + L C P P I W G+ ++ D +A S
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAY--------S 4620
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
LK+T G YT +A N G +++ + + P+ K++ +VI
Sbjct: 4621 HLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV------AVI 4674
Query: 754 LSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
+ +TW N P+ K L + S+ IL +K D +YT K N
Sbjct: 4675 TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITWYRN 869
+ E E + ++ V ++ L VT +P+ + + W +N
Sbjct: 4735 RRHSIPHLTSAFEGVPE--------VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN 4786
Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
++ + + I + N LV+ NV+ + D G YKCVASNS GK+ ++ +
Sbjct: 4787 DQKMLDDDAI---YVLPNNSLVLLNVE-KYDEGVYKCVASNSIGKAFDDTQLNV 4836
Score = 57.6 bits (133), Expect = 9e-08
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 19/271 (7%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
PQ I K+ G V L G P PTITW K+ K ++ + +T+
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL--- 4626
Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
D G YT A+NS G + SA I V+ +P IT E+ + +
Sbjct: 4627 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERN--QAYS 4684
Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
R +TW N + P +F N LVI + S + GD + +
Sbjct: 4685 R-------GLTW-EYNGVPMPKNLAGIHF-MNNGSLVILDT-SSLKEGDLELYTCKVRNR 4734
Query: 915 SSHG-ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDH 972
H +T E V VK + K E G +V+L+C+ TS ++T K + +D
Sbjct: 4735 RRHSIPHLTSAFEGVPEVKTIDK-VEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDD 4793
Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
+ I D GV KC+ +
Sbjct: 4794 -DAIYVLPNNSLVLLNVEKYDEGVYKCVASN 4823
Score = 56.0 bits (129), Expect = 3e-07
Identities = 61/321 (19%), Positives = 120/321 (37%), Gaps = 22/321 (6%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P + P GS L C + P+P I+W G +I EN I +D
Sbjct: 4136 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGEN-GHTIGAD----- 4189
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
L I ++ + Y A N G +L ++ K + +G
Sbjct: 4190 GTLHIEKAEE-RHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING---SEGTET 4245
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ + + + +W KN P+ + + + + ++ D+G Y+ A N G
Sbjct: 4246 VIKCE-IESESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAG 4304
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A + V P + R + V + + L + P P+ITWY++NE+
Sbjct: 4305 NATQKTNLNV-------GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNEL 4357
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
++ + + + + ++ +++ S +G Y C A N + + + + +
Sbjct: 4358 LT-NTGVDETATTKKKSVIFSSI-SPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 4415
Query: 933 HLQKSYETEEGKTVILECQTS 953
+ S T +TV L C +
Sbjct: 4416 RMNVS--TNPRQTVFLSCNAT 4434
Score = 54.8 bits (126), Expect = 6e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 24/347 (6%)
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
TI ++ DAG Y+ R+ +N G+ V+ V + P P I + + S+ + E
Sbjct: 485 TIPELSLKDAGEYECRVISNNGNYSVKTRVETRESP-----PEIFGVRNVSVPL--GEAA 537
Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA-VNEVDISDA 1464
ST VE + T +V N T+ + N + RA A V E +A
Sbjct: 538 FLHCSTRSAGEVEIRW--TRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNA 595
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
+ + ++ ++ P+V+ +++ E + L+C G P+P+V WY G+ L
Sbjct: 596 GGMST--RKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLN 653
Query: 1525 --AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
++ Y+C A + G+ + + + P + I I+
Sbjct: 654 DYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEI----IQN 709
Query: 1583 KHKVGDEWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
K VG V+ I G P P++ W+KNG L +Y K + I K
Sbjct: 710 KMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDY---IKINEGQLHIMGAKDED 766
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
+ Y+ N AG L V P+ E P +R VT++
Sbjct: 767 AGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQ 813
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C N G+ E + + + + PV + QK + ++ + G P P VIW
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+GN + DK + E S++RI++L S++ + A N AGT+S + ++ P+
Sbjct: 1773 IDGNDV--DKSW--LFDESLSLLRIEKL-TGKSAQISCTAENKAGTASRDFFIQNIAAPT 1827
Query: 1668 -KPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
K EG I RES TI P+ G ++T
Sbjct: 1828 FKNEGD--QETIFRESETITLDCPVSLGDFQIT 1858
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
K +G EC VEGYP PQ++W R ++ Y D + T++ E D+
Sbjct: 4053 KQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII--EARSLDS 4110
Query: 579 GTFTCVAKNAAGFASS--TTELIV 600
G + C A N AG A T E++V
Sbjct: 4111 GIYLCSATNEAGSAQQAYTLEVLV 4134
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
PI + + +T G V+ +C VE P +TWFR+ I D + Y + + TL
Sbjct: 1362 PIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAI--GTDTKGYVVESD-GTL 1418
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
VI+ EDA +TC A N AG A + ++ V A
Sbjct: 1419 VIQSASVEDATIYTCKASNPAGKAEANLQVTVIA 1452
Score = 48.0 bits (109), Expect = 7e-05
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ T E S P V +G C+V G P P + W + +P +
Sbjct: 3116 EQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDG---EPYTSDLL 3172
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ ++ L +RE D GT+TC+A N AG + +TT++ V P
Sbjct: 3173 QFST-KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C A N G + + P I + + HK GD+ + G+P P + WY
Sbjct: 4295 YSCTAANKAGNATQKTNLNVGVAPKI-MERPRTQVVHK-GDQVTLWCEASGVPQPAITWY 4352
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
K+ L N T +K SVI + S + YT +A N ++ ++ L V P
Sbjct: 4353 KDNELLTNTGVDETATTKKKSVI-FSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 4410
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T+ +AP +E+ R + G V C+ G P+P ITW++ ++ + +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET--A 4367
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+++ + P AG +TC A+N +LIV P
Sbjct: 4368 TTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIP 4409
Score = 45.2 bits (102), Expect = 5e-04
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F+ K + G+ V+ C G P P ITW + +I+ S+ F++ Y L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-FEIAYSH-----L 4622
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ D+G +TC+A+N+ G SST +
Sbjct: 4623 KVTLNSTSDSGEYTCMAQNSVG--SSTVSAFI 4652
Score = 44.8 bits (101), Expect = 7e-04
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V C+ G P+P++ W+ + + +Q+ D L IR+ D GT+ C A
Sbjct: 628 VNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSK---FLYIRDATHHDEGTYECRAM 684
Query: 587 NAAGFASSTTELIVEAP 603
+ AG A TT+L++ P
Sbjct: 685 SQAGQARDTTDLMLATP 701
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 508 MAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+AP F E +R G+ C +G P P ITW + I+P+ D +++D
Sbjct: 2475 VAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPN-DRYVFFDAGR- 2532
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGF--ASSTTELIV 600
L I + D G +TC+A N+ G +T E+I+
Sbjct: 2533 -QLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVII 2568
Score = 41.1 bits (92), Expect = 0.008
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 25/102 (24%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
+ VF KPT E VE G + + EC+++G+P+P I+W +K +
Sbjct: 3294 IDVFTKPTFETHETTFNIVE---------GESAKIECKIDGHPKPTISW------LKGGR 3338
Query: 555 DFQMYYDDDNVA------TLVIREVFPEDAGTFTCVAKNAAG 590
F M DN+ TL+I + D G +TCVA N+ G
Sbjct: 3339 PFNM----DNIILSPRGDTLMILKAQRFDGGLYTCVATNSYG 3376
Score = 39.9 bits (89), Expect = 0.019
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
+ KP KN T +EL C G P P +TW +DGK ++ +K
Sbjct: 4573 IVKP-KNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIA-YSHLKVTLNSTS 4630
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGI 1567
Y C+A N G S + +
Sbjct: 4631 DSGEYTCMAQNSVGSSTVSAFINV 4654
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 11/91 (12%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E + P ++ R +G+T CQV G P P +TW R K + F
Sbjct: 3209 TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNG---KEIEQFN---- 3261
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
L IR D G ++C+A N AG A
Sbjct: 3262 ----PVLHIRNATRADEGKYSCIASNEAGTA 3288
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P ++ +C +G P PQ+ W TA+ + + D + I V D G
Sbjct: 3965 PAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ---INNVSLSDKGV 4021
Query: 581 FTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613
+TC A+N AG + + +V+AP+ +G V
Sbjct: 4022 YTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV 4055
Score = 37.9 bits (84), Expect = 0.078
Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 26/201 (12%)
Query: 408 FEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKG 467
FE V R GDT+ + AE+ ++ V + D S Q+ K+ EK
Sbjct: 2763 FEKEREEVVARVGDTMLLTCN--AESSVPLSSVYW---HAHDESVQNGVITSKYAANEKT 2817
Query: 468 WVPAQYLMDENNY---TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPD 523
+D+ + T + + +K KL V E P ++Q + PI +
Sbjct: 2818 LNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIIL---------- 2867
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + +C G P P I + + + S + + +TLVI E G +TC
Sbjct: 2868 GKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIG-----STLVIDNPQKEVEGRYTC 2922
Query: 584 VAKNAAGFASSTTELIVEAPL 604
+A+N AG S +++VE L
Sbjct: 2923 IAENKAG--RSEKDMMVEVLL 2941
Score = 35.9 bits (79), Expect = 0.32
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E +P + +R P G C +I W R A + + +
Sbjct: 512 TRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTER--- 568
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
+ TL I V DAG + C+A+NA G ++ L I+E P
Sbjct: 569 NPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPP 611
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P + W K+G KL D ++ I S +++ S S +YT A N+ G+S+V
Sbjct: 4595 GPPHPTITWAKDG-KLIEDSKFEIA----YSHLKVTLNSTSDSGEYTCMAQNSVGSSTVS 4649
Query: 1658 VTLKV 1662
+ V
Sbjct: 4650 AFINV 4654
Score = 33.9 bits (74), Expect = 1.3
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 523 DGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C EG P P W F Q + K + ++ ++++ T+V+ V G +
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLPKEA----VFVNNNH--TVVVNNVTKYHTGVY 1982
Query: 582 TCVAKNAAGFASSTTELIVEA-PLSDHG---SEMTVXXXXXXXXXXXXADIL-EGIPPTF 636
C A N G A T + V P + G SE+TV D + GI T
Sbjct: 1983 KCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 637 SKKP 640
+ KP
Sbjct: 2043 NGKP 2046
Score = 33.9 bits (74), Expect = 1.3
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+ +++ C+V G P P +TW + + + Q+ + +V E+ G++
Sbjct: 2112 ENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQF-KIVHAEI--AHKGSYI 2168
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
C+AKN G A + ++ I+ P+ G
Sbjct: 2169 CMAKNDVGTAEISFDVDIITRPMIQKG 2195
Score = 33.9 bits (74), Expect = 1.3
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G +V +C+V P + W + K D +Y +N +LV+ V D G +
Sbjct: 4762 NGDSVVLDCEVTSDPLTTHVVWTKNDQ--KMLDDDAIYVLPNN--SLVLLNVEKYDEGVY 4817
Query: 582 TCVAKNAAGFASSTTELIV 600
CVA N+ G A T+L V
Sbjct: 4818 KCVASNSIGKAFDDTQLNV 4836
Score = 32.7 bits (71), Expect = 3.0
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 510 PIFVEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P+FVE + + + + +CQV G P+P + W + S F D++++
Sbjct: 1736 PVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLF-----DESLSL 1790
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593
L I ++ + A +C A+N AG AS
Sbjct: 1791 LRIEKLTGKSA-QISCTAENKAGTAS 1815
Score = 31.5 bits (68), Expect = 6.8
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
TP GS C V GYP P I+W IK ++ D TL I E E
Sbjct: 4147 TPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD---GTLHI-EKAEERHL 4202
Query: 580 TFTCVAKNAAG 590
+ C AKN AG
Sbjct: 4203 IYECTAKNDAG 4213
>Z47068-9|CAA87336.1| 5198|Caenorhabditis elegans Hypothetical protein
F15G9.4b protein.
Length = 5198
Score = 213 bits (520), Expect = 1e-54
Identities = 282/1187 (23%), Positives = 464/1187 (39%), Gaps = 142/1187 (11%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + EC +E ITW RQ K Q + + L I + PEDA +++C
Sbjct: 2957 GDPLTLECPIEDTSGVHITWSRQFG--KDGQLDMRAQSSSDKSKLYIMQATPEDADSYSC 3014
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+A N AG A + ++ V P G + EGIPP
Sbjct: 3015 IAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCR-TEGIPP--------- 3064
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
PE I+W G+ I+ ++ + D+ L+I N+K
Sbjct: 3065 -----------------PE--ISWFLDGKPILEMPGVTYK-QGDLS-----LRIDNIKPN 3099
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
QEG YT VA N+ G A ++I EPP+V+ + M V +G + +V GNP
Sbjct: 3100 QEGRYTCVAENKAGRAEQDTYVEI----SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPE 3155
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
P + W K+ +P + S L+ + D G YT A N G ++T+ + V
Sbjct: 3156 PVVNWLKDGEPYTS-DLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV- 3213
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
PP + + + KE T + +VT PVP +TW RN + I + F
Sbjct: 3214 ------LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-------EQF 3260
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
N L I N + D G Y C+ASN AG + A IDV K TF H + ++ E
Sbjct: 3261 ---NPVLHIRNA-TRADEGKYSCIASNEAGTAV--ADFLIDVFTKPTFETH-ETTFNIVE 3313
Query: 943 GKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
G++ +EC+ H T W + + MD+ II R D G+ C+
Sbjct: 3314 GESAKIECKIDGHPKPTISWLKGGRPFN-MDN--IILSPRGDTLMILKAQRFDGGLYTCV 3370
Query: 1001 V------KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE 1054
+Q+ + K I E I + V ++ + + + T V W+R G+
Sbjct: 3371 ATNSYGDSEQDFKVNVYTKPYIDETIDQTPK-AVAGGEIILKCPVLGNPTPTVTWKR-GD 3428
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEIIT 1111
P +++ ++ I + + D G+YSCI +E+ T V P +
Sbjct: 3429 DAVPNDSRHTIVNNYDLK---INSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR 3485
Query: 1112 RLQN-QKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
+ N +V + + T + +T + WF+ + + ++ DG + I
Sbjct: 3486 KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDG--SHITINKAK 3543
Query: 1170 LDDAGEYSC----EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223
L D G+Y C E G S IL + P I+ + + + + A T YL I
Sbjct: 3544 LSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVART-IYLECPISGIP 3602
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
DV W K I T+ +++ T I DQ YTC + K++ +
Sbjct: 3603 QPDVIWTKNGMDINMTDSRVILAQ-NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 3661
Query: 1282 EVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDE-----WIVNSKIIKKCKHTK 1335
+V+ PP+ + + IKR G +TL + D+ W +S+ +
Sbjct: 3662 DVLS-PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDN 3720
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I LTI + +AG+Y N G A +E V IL SPP +++I +
Sbjct: 3721 VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL---SPP----VIDISRN 3773
Query: 1396 SINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-SVKNITKTQT--------SIQNLKT 1445
+ +P+ N TI+ V + +W+ + K +T + +Q L+T
Sbjct: 3774 DV-----QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRT 3828
Query: 1446 NSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+S + ++ A N+ + + + + + S + P+K + E I L C
Sbjct: 3829 DSDHAGKWSCVAENDAGVKELEMVLDVF----TPPVVSVKSDNPIKAL----GETITLFC 3880
Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
G P P++ W + G + A+ + + Y C A N G
Sbjct: 3881 NASGNPYPQLKWAKGGSLIFDSPDGARISLKG-ARLDIPHLKKTDVGDYTCQALNAAGTS 3939
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
E S V + P I D+ + + + +G P P++ W NG L +
Sbjct: 3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTP- 3998
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
IT ++ I+I + S YT A N AG+ ++ + V P
Sbjct: 3999 GITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 4045
Score = 194 bits (473), Expect = 6e-49
Identities = 268/1073 (24%), Positives = 421/1073 (39%), Gaps = 82/1073 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
PTF + EG +EC++ P+P I+WL KG +NI ++ D
Sbjct: 3300 PTFETHETTFNIVEGESAKIECKIDGHPKPTISWL-KGGRPFNMDNIILSPRGD------ 3352
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I ++F G YT VA N G++ + + T + + K++ G +I
Sbjct: 3353 TLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGEII 3409
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
L V+GNP PT+TW + + A+P S H TI+ +K V T A I
Sbjct: 3410 LKCPVLGNPTPTVTWKRGD---DAVPNDS---RH--TIVNNYDLKINSVTTEDAGQYSCI 3461
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A A E P F+ + + V E TI + VT P+PSI+W+R ++
Sbjct: 3462 AVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKP 3521
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ + + + DG +I + N D G Y C ASN AG S + I V
Sbjct: 3522 VYLYDRYSISPDGSHITI---NKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKS 3578
Query: 933 HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
++ + +T+ LEC S W N +I+ D R I+ +
Sbjct: 3579 NIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNN-ETFGIENVQ 3637
Query: 991 XXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEV------EI 1040
D G C + + + + + PEF I Q +E D L +I
Sbjct: 3638 VTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDI 3697
Query: 1041 NSETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ DV W +D + + D G RKL I S+ + G Y+CI + + A
Sbjct: 3698 ADQVMDVSWTKDSRALDGDLTDNVDISDDG--RKLTISQASLENAGLYTCIALNRAGEAS 3755
Query: 1100 VTV-VEL--PPEI-ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQ 1153
+ VE+ PP I I+R Q N+ T G ++W K+G E+ +I+
Sbjct: 3756 LEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR 3815
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
+ G Q L+I D D AG++SC + G + +L V P + +++ I
Sbjct: 3816 IVEQG--QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKAL 3872
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
T + + W K S+I D+ IS +K L I + D +YTC
Sbjct: 3873 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQ 3931
Query: 1270 LLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
L+A T++ V V V PP+I + R+ +TL Q P P W +N
Sbjct: 3932 ALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGT 3991
Query: 1327 IIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--S 1382
+ H+ P I S S + I V +D G+Y EN G ++ NV ++ P S
Sbjct: 3992 AL---THSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS 4048
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQ 1441
G ++E + + I C E + ++ ++T V+ +T +I
Sbjct: 4049 NGGTKQVIEGELAVIE-CLVEGYPAPQ---VSWLRNGNRVETGVQ-GVRYVTDGRMLTII 4103
Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
++ S + A NE + + T E V+ KI + T +T L
Sbjct: 4104 EARSLDSGIYLCSATNEAGSAQQAYTLE---VLVSPKIITSTPGV----LTPSSGSKFSL 4156
Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G P P ++W +G +K + + Y+C A ND G
Sbjct: 4157 PCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADT 4216
Query: 1561 TSCVVGIQQKPVITIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
V P I+ S N I G E ++ IE E W KNG L
Sbjct: 4217 LEFPVQTIVAPKISTSGNRYINGSE--GTETVIKCEIES-ESSEFSWSKNGVPLLPSN-- 4271
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
N+ E +I+I + S +Y+ A+N AG ++ + L V P E P
Sbjct: 4272 NLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP 4324
Score = 187 bits (456), Expect = 7e-47
Identities = 248/1061 (23%), Positives = 417/1061 (39%), Gaps = 91/1061 (8%)
Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
G DI L C L + W G E D +V I SD H L IT+ K
Sbjct: 1657 GKDISLSCDLQTESDDKTTFVWSINGSE--SDRPDNVQIPSDGHR----LYITDAKPENN 1710
Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSAQVVGNPR 763
G Y N G+A + L + EPP +EP+ + + +IL QV GNP+
Sbjct: 1711 GKYMCRVTNSAGKAERTLTLDVL----EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPK 1766
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEGIAETSAVITV 822
PT+ W + V KS S+++L+ +K+ + + AEN G A I
Sbjct: 1767 PTVIWKIDGNDVD----KSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFI-- 1820
Query: 823 EEPTEENAEPPLFINRFQEITV-KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
+N P F N + T+ +E TI L V+ ITW + ++ ++ I
Sbjct: 1821 -----QNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWMKQGLPLTENDAI-- 1872
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
F +N L I N + + + Y CVA+N+AG+ S V + V + +K+ + E
Sbjct: 1873 -FTLDNTRLTILNANRDHED-IYTCVANNTAGQVSKDFDVVVQV--LPKIKNAVVTLEIN 1928
Query: 942 EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
EG+ +IL C + T + KW N+ ++ +E + GV KC
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLP----KEAVFVNNNHTVVVNNVTKYHTGVYKC 1984
Query: 1000 IVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWERDG 1053
+ Q T+ V T P F L + E+ + +E + + A + W +G
Sbjct: 1985 YATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNG 2044
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
+ + + G R L+I + D G Y+C + +E+ A T V++PP I+
Sbjct: 2045 KPFLAETDGVQTLAGG--RFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
V + N E+T K + +V W KDG + +Q+ +G Q+ KI +
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEG--QQFKIVHAE 2160
Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIP---DET 1224
+ G Y C N TA ++ + I + + + I +V A L + P D+
Sbjct: 2161 IAHKGSYICMAKNDVGTAEISFDVDIITRPM-IQKGIKNIVTAIKGGALPFKCPIDDDKN 2219
Query: 1225 L--DVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLK 1280
+ W + I+ + E + R L I TE+D+ +Y+C V DA +
Sbjct: 2220 FKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDF 2279
Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KKCKHTKP 1336
V PP I+ D ++ S VTL P+P+ W + + I + P
Sbjct: 2280 KATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIP 2339
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVTILDKPSPPGKPNILEIDS 1394
+ + L I +++ DAG Y +N+ G DV +NV + K G P+ E
Sbjct: 2340 NGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ 2399
Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
+ + P I ++ + + + +++ + + + L+ S ++
Sbjct: 2400 NE-RVVISCPVYARPPAKITWLKAGKPLQSDKFVKT-SANGQKLYLFKLRETDSSKYTCI 2457
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPK 1512
A NE A +KV + + +P+ ++P ++ IT L C G P P
Sbjct: 2458 ATNE-----AGTDKRDFKV---SMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT 2509
Query: 1513 VTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+TW +DG ++ ++ Y CIA N G + + +
Sbjct: 2510 ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIP 2569
Query: 1571 PVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK---EYNITTKEK 1626
PVI E + E + G+ +V W K+G + D + I
Sbjct: 2570 PVIDGERREAVAVIEGFSSELFCDSNSTGV---DVEWQKDGLTINQDTLRGDSFIQIPSS 2626
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+ ++S S +YT N AG + V D PS
Sbjct: 2627 GKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS 2667
Score = 187 bits (456), Expect = 7e-47
Identities = 229/1061 (21%), Positives = 423/1061 (39%), Gaps = 83/1061 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F + K + G + L+C P P I ++ G+ + + + + S
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--------GS 2905
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I N +K EG YT +A N+ G + +++++ PP++ + ++ V+ G+ +
Sbjct: 2906 TLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLL----PPKLSKEWINVEVQAGDPLT 2961
Query: 754 LSAQVVGNPRPTITWCKN-NKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
L + ITW + K + + +S D + I++ +D Y+ A N
Sbjct: 2962 LECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATP-EDADSYSCIAVNDA 3020
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G AE +TV P P +F + F + T+++ R P P I+W+ + +
Sbjct: 3021 GGAEAVFQVTVNTP------PKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGK 3074
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTF 930
I +T + ++ L I N+ G Y CVA N AG++ V I + +V
Sbjct: 3075 PILEMPGVT--YKQGDLSLRIDNIKPN-QEGRYTCVAENKAGRAEQDTYVEISEPPRVVM 3131
Query: 931 VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
+ + EG+ + C+ + W + + + +++Q +
Sbjct: 3132 ASEVMR---VVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTS----DLLQFSTKLSYLHLR 3184
Query: 988 XXXXXDVGVIKCIV--KDQETSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSET 1044
D G CI K E+ T V+ +P I + + + KE + ++ ++
Sbjct: 3185 ETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 1045 AD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102
V W+R+G+ + E+ + L+IRN + DEG+YSCI +E+ TA
Sbjct: 3245 VPYVTWKRNGK---------EIEQFNPV--LHIRNATRADEGKYSCIASNEAGTAVADFL 3293
Query: 1103 --VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
V P T + +G A E ++ + W K G N + + +
Sbjct: 3294 IDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMDN---IILSPR 3350
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTL-RLPEFILVPANTD 1213
L I D G Y+C NS + + +P I+ T+ + P+ + A +
Sbjct: 3351 GDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGE 3407
Query: 1214 AYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
L + + T VTW + + + + T++++ L I T +D +Y+C+ ++
Sbjct: 3408 IILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNY---DLKINSVTTEDAGQYSCIAVN 3464
Query: 1273 --AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
TT EV+ P + Y + +T+ + P P+ W K +
Sbjct: 3465 EAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPV-- 3522
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
+ + SI + +TI K + +D G Y R N G +D+++ + IL P K NI+
Sbjct: 3523 YLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDIDLILKIL-VPPKIDKSNII 3581
Query: 1391 EIDSSSI--NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
+ + I + P + + + +I+ T+ + I+N++
Sbjct: 3582 GNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIK-ETKIQSPTVEKPLKNIT-TEPNEDIE-LTCIF 1505
R+ A N + + + + + PT+++ IT T P + E +
Sbjct: 3642 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
V K + DG + + R Y CIA N GE V
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGR-KLTISQASLENAGLYTCIALNRAGEASLEFKV 3760
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I PVI IS D++ + V ++ + G P P + W KNG ++ +D+ NI E
Sbjct: 3761 EILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE--NIRIVE 3818
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ V++I H+ K++ A N AG +E+ L V+ P
Sbjct: 3819 QGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859
Score = 181 bits (440), Expect = 6e-45
Identities = 248/1089 (22%), Positives = 419/1089 (38%), Gaps = 83/1089 (7%)
Query: 632 IPPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
+PPT K K + E S + L C PEPDI W FK E + ENI+ I +
Sbjct: 2285 VPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITW-FKDGEAIHIENIADIIPNG-E 2342
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748
+ + LKIT +K+ G YT A N G + + + T K E + +S +Q
Sbjct: 2343 LNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYES---QQ 2399
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKA 807
E V++S V P ITW K KP+++ K+ + + + K ++ D YT A
Sbjct: 2400 NERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSANGQKLYLFKLRET-DSSKYTCIA 2458
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G + +++ + + P + R ITV L +P P+ITW
Sbjct: 2459 TNEAGTDKRDFKVSML--VAPSFDEPNIVRR---ITVNSGNPSTLHCPAKGSPSPTITWL 2513
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ I P++ FD +L I+ + D G Y C+A+NS G + + +
Sbjct: 2514 KDGNAIEPNDRYVF-FDAGR-QLQISKTEGS-DQGRYTCIATNSVGSDDLENTLEVIIPP 2570
Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYH-----NKKEISGMDHREIIQEGRX 981
V + +++ EG + L C ++ T V +W N+ + G +I G+
Sbjct: 2571 VIDGER-REAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKK 2629
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEV 1038
D G CIV++ + + P +L + + V V
Sbjct: 2630 MSFLSARKS--DSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANI-QTIVPYYPV 2686
Query: 1039 EIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
EIN S V W D + ++P Y+ G K+ + V G Y+C ++
Sbjct: 2687 EINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV--RSQVEHAGTYTCEAQN 2744
Query: 1094 ESCTAE---VTVVELPPEIITRLQNQKVNKGNKA--TFEIELTKGDALVRWFKDGSEIQF 1148
A + V PP + G+ T E + + V W +Q
Sbjct: 2745 NVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQ- 2803
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLP 1203
+ I ++ L + + LDD G Y C N K ++ +E P +L
Sbjct: 2804 NGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLY 2863
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
IL T P T + + K + ++++ +I TL+I ++ +
Sbjct: 2864 PIILGKRLTLDCSATGTPPPT--ILFMKDGKRLNESDEVDIIGS----TLVIDNPQKEVE 2917
Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
YTC+ + +S + VEV+ PPK+ ++ G +TL + + W
Sbjct: 2918 GRYTCIAENKAGRSEKDMMVEVL-LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW 2976
Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
+ S KS L I + DA Y N+ G A+ VT+ P
Sbjct: 2977 SRQFGKDGQLDMRAQSSSDKS-KLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Query: 1382 SPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
G + EI + + E I +++ + + I ++ K I
Sbjct: 3036 KIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFL-DGKPILEMPGVTYKQ-GDLSLRI 3093
Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
N+K N R+ A N+ + +E Y ++ + P V + +
Sbjct: 3094 DNIKPNQEGRYTCVAENK---AGRAEQDTYVEIS-----EPPRVVMASEVMRVVEGRQTT 3145
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-XYKCIAFNDHGEV 1559
+ C G P+P V W +DG+ + + + Y CIA N GE
Sbjct: 3146 IRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGES 3205
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+T+ V + P I +E+ + K G+ ++V + G P P V W +NG ++E ++
Sbjct: 3206 QTTTDVEVLVPP--RIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIE---QF 3260
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
N V+ I+ R+ KY+ ASN AGT+ + + V+ KP+ +
Sbjct: 3261 N-------PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE 3313
Query: 1680 RESVTIEWK 1688
ES IE K
Sbjct: 3314 GESAKIECK 3322
Score = 180 bits (437), Expect = 1e-44
Identities = 229/1065 (21%), Positives = 423/1065 (39%), Gaps = 85/1065 (7%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP + V EG + C + PEP + WL GE D ++ +
Sbjct: 3126 PPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSD-----LLQFSTKL-- 3178
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S L + GTYT +A N+ GE+ +++ PP++ + + + ++G +
Sbjct: 3179 SYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLV----PPRIEDEERVLQGKEGNTY 3234
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ QV G P P +TW +N K ++ + + ++ DEG Y+ A N G
Sbjct: 3235 MVHCQVTGRPVPYVTWKRNGKEIEQF--------NPVLHIRNATRADEGKYSCIASNEAG 3286
Query: 813 IAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
A +I V +PT E E + E + K+ ++ +P P+I+W +
Sbjct: 3287 TAVADFLIDVFTKPTFETHE--------TTFNIVEGESAKIECKIDGHPKPTISWLKGGR 3338
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
+ + I + G+ + ++ D G Y CVA+NS G S +V + K
Sbjct: 3339 PFN-MDNIILSPRGDTLMILKA---QRFDGGLYTCVATNSYGDSEQDFKVNV-YTKPYID 3393
Query: 932 KHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
+ + ++ + G +IL+C + T + W + I+
Sbjct: 3394 ETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNN---YDLKINSV 3450
Query: 990 XXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEINSE-T 1044
D G CI V + T E I P F+RK + +EV E D ++ + S
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
+ W R G+ ++Y G + I + D G+Y C +E+ T+++ +
Sbjct: 3511 PSISWFR-GDKPVYLYDRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLIL 3567
Query: 1103 -VELPPEI--ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDG 1158
+ +PP+I + N E ++ V W K+G +I ++ ++ +
Sbjct: 3568 KILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS-RVILAQ 3626
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA-------ILTVEEPSINFTLRL--PEFILVP 1209
+ I + + D G Y+C N A +L+ E I+ T E +
Sbjct: 3627 NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTIT 3686
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
L +I D+ +DV+W K ++ D ISD R L I + + ++ YTC
Sbjct: 3687 LTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISD-DGRKLTISQASLENAGLYTC 3745
Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
+ L+ L+ +V P ++D R + ++ + P P+ +W+ N
Sbjct: 3746 IALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNG 3805
Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
K + ++ + I + L I + ++ AG + EN+ G ++EM + + P
Sbjct: 3806 KEVTDDENIR--IVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSV 3863
Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
K N ++ +I + + N + + D+ + + ++ + I +LK
Sbjct: 3864 KSDNPIKALGETITLFCNASGNP-YPQLKWAKGGSLIFDSPDGARI-SLKGARLDIPHLK 3921
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
+ A+N S+AS + + V+ +I ++ + + + L C+
Sbjct: 3922 KTDVGDYTCQALNAAGTSEASVSVD---VLVPPEINRDGIDMSPR---LPAQQSLTLQCL 3975
Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P++ W +G L T T + Y C A N G
Sbjct: 3976 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 4035
Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
V + Q PV ISN KQ + G+ ++ ++EG P P+V W +NGN++E + +
Sbjct: 4036 MYNVDVVQAPV--ISNGGTKQVIE-GELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GV 4091
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ I E + S Y A+N AG++ TL+V P
Sbjct: 4092 RYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 4136
Score = 177 bits (431), Expect = 7e-44
Identities = 270/1198 (22%), Positives = 453/1198 (37%), Gaps = 124/1198 (10%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V +C G P P+I W + ++ + + Y L+I + ED G FTC+A+
Sbjct: 810 VTLQCLAVGIPPPEIEWQKGNVLLATLNNPR--YTQLADGNLLITDAQIEDQGQFTCIAR 867
Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
N G S +T L+V +S +L +PP + +
Sbjct: 868 NTYGQQSQSTTLMVTGLVS---------------------PVLGHVPP-------EEQLI 899
Query: 647 EGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG D+ L C +V P+P I W+ K ++ V +E ++ IE S+L++ E
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWI-KDDKPV-EEGPTIKIEGG----GSLLRLRGGNPKDE 953
Query: 706 GTYTVVAVNREGEASLPI-VLKIKTGE----KEPPQVIEPLKSMI-------------VR 747
G YT +AV+ G ++L I V IK E E V +P S + V
Sbjct: 954 GKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVL 1013
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKD-EGVYTL 805
GE + V G P P ITW + +P+ P D T T++ K K GVYT
Sbjct: 1014 DGEGFAIPCVVSGTPPPIITWYLDGRPI--TPNSRDFTVTADNTLIVRKADKSYSGVYTC 1071
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
+A NS G E I + P+ + + V +P P IT
Sbjct: 1072 QATNSAGDNEQKTTIRI-------MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVIT 1124
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
W + + T+ E+ L I NV +E G + C A N+AG + +T+
Sbjct: 1125 W------LLDDKPFTEGVVNEDGSLTIPNV-NEAHRGTFTCHAQNAAGNDTRTVTLTVHT 1177
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS---HTVSTKWYHNKKEISGMDHREIIQEGRXX 982
++ +K + ++LEC V Y +K S + I ++G
Sbjct: 1178 TPTINAENQEKI--ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG--- 1232
Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
+ GV C V + L T+ E + + + V +EI
Sbjct: 1233 ALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPC 1292
Query: 1043 ETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
V W ++G +K + K+ + G +R I +D G Y+C++ +E+ T
Sbjct: 1293 RATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR---IYEADKNDIGNYNCVVTNEAGT 1349
Query: 1098 AEVTV---VELPPEIITRLQ-NQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152
+++T V+ PP I+ Q N G++ + + A V WF+ G I
Sbjct: 1350 SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG--IAIGTDT 1407
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA---ILTVEEPSINFTLRLPEFIL 1207
+ + L I ++DA Y+C+ N K A + + P I + + +
Sbjct: 1408 KGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESI 1467
Query: 1208 VPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
++ + + ++WY K +I+D + D KR L + K D Y
Sbjct: 1468 KESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD--KRKLHVFKAKITDSGVY 1525
Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV +A +V P +D Y+++ K G +VTL FP P W+V
Sbjct: 1526 KCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVV 1585
Query: 1324 NSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
+ +++ K K ++ + +L V G Y ++ D+++ +++L P
Sbjct: 1586 DGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPI 1645
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
N+ I++ D + + T + + E D + + + + + I +
Sbjct: 1646 VGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPS-DGHRLYITD 1704
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
K ++ ++ N + +E T V++ P E K I P I L
Sbjct: 1705 AKPENNGKYMCRVTNS---AGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNP---IILQ 1758
Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
C G P+P V W DG + + ++ C A N G
Sbjct: 1759 CQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRD 1817
Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNI 1621
IQ T NE ++ E + + ++ W K G L END I
Sbjct: 1818 FF--IQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA---I 1872
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
T + T + I R H YT A+NTAG S + + V P K + V+ EI+
Sbjct: 1873 FTLDNTR-LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP-KIKNAVVTLEIN 1928
Score = 157 bits (380), Expect = 1e-37
Identities = 244/1092 (22%), Positives = 419/1092 (38%), Gaps = 106/1092 (9%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GES 751
+ + +K G YT + N GEA + +PP + + L S ++
Sbjct: 2630 MSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN----DPPSISDELSSANIQTIVPYYP 2685
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
V ++ V G+P P + W ++KP++ A ++G+T I +V+ G YT +A
Sbjct: 2686 VEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV---RSQVEHAGTYTCEA 2742
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITW 866
+N+ G A ++ V PP F +E+ + T+ L + P+ S+ W
Sbjct: 2743 QNNVGKARKDFLVRV-------TAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYW 2795
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ ++E + + IT + L +TN+ + D G Y C A N AG + ++ + +E
Sbjct: 2796 HAHDESVQ-NGVITSKYAANEKTLNVTNIQLD-DEGFYYCTAVNEAGITKKFFKLIV-IE 2852
Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXX 984
F+ QK Y GK + L+C + T + + + K ++ D +II
Sbjct: 2853 TPYFLDQ-QKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII----GSTL 2907
Query: 985 XXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
G CI +++ M+V P+ ++ + EV+ D LE I
Sbjct: 2908 VIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIE 2967
Query: 1042 SETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + W R + K + + KLYI + D YSCI +++ AE
Sbjct: 2968 DTSGVHITWSR--QFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEA 3025
Query: 1101 T---VVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSEIQFSNHIQL 1154
V PP+I + + T EI T+G + WF DG I +
Sbjct: 3026 VFQVTVNTPPKIFGDSFSTTEIVAD-TTLEIPCRTEGIPPPEISWFLDGKPILEMPGV-- 3082
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
T L+I + + G Y+C + G ++ + + EP + E + V
Sbjct: 3083 TYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR--VVMASEVMRVVE 3140
Query: 1211 NTDAYLTVEI---PDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
+ E+ P+ V W K + D +F+ K L +R+ T D Y
Sbjct: 3141 GRQTTIRCEVFGNPEPV--VNWLKDGEPYTSDLLQFS----TKLSYLHLRETTLADGGTY 3194
Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
TC+ + +S T VEV+ PP+I D ER + K G+ + P P W N
Sbjct: 3195 TCIATNKAGESQTTTDVEVL-VPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN 3253
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K I+ + L I+ D G Y N G A + + + KP+
Sbjct: 3254 GK----------EIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPT-- 3301
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI------SVKNITKTQT 1438
E ++ NI G S I ++ T W+ ++ NI +
Sbjct: 3302 -----FETHETTFNIV------EGESAKIECKIDGHPKPTISWLKGGRPFNMDNIILSPR 3350
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNE 1497
L + RF V + ++ + +KV TK T+++ K +
Sbjct: 3351 G-DTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVA---GG 3406
Query: 1498 DIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+I L C G P P VTW R D ++ T N Y CIA N+
Sbjct: 3407 EIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEA 3466
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G + T + KP ++ + + D + + P P + W++ +
Sbjct: 3467 GNLTTHYAAEVIGKPTFVRKGGNLYEVIE-NDTITMDCGVTSRPLPSISWFRGDKPVYLY 3525
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
Y+I+ S I I + K S KY ASN AGTS +++ LK+ P + +I
Sbjct: 3526 DRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGN 3583
Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
++ + TI + P+ G+ K+ D N + ++ ET+ I+ + +
Sbjct: 3584 PLAIVARTIYLECPI--SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1737 YMFRVIAQNPVG 1748
+ A N G
Sbjct: 3642 GRYTCTATNRGG 3653
Score = 155 bits (377), Expect = 2e-37
Identities = 223/1013 (22%), Positives = 380/1013 (37%), Gaps = 81/1013 (7%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L I + K G+Y N G A+ L ++ PP ++ V + S++L
Sbjct: 2063 LHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQV----PPTIVNEGGEYTVIENNSLVL 2118
Query: 755 SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+V G P P +TW K+ +PV K++ S+G I ++ +G Y A+N
Sbjct: 2119 PCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIV---HAEIAHKGSYICMAKNDV 2175
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG---TIKLVARVTRNPVPSITWYR 868
G AE S + + P+ + I KG K +N I W R
Sbjct: 2176 GTAEISFDVDI-------ITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLR 2228
Query: 869 NNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
N + I +E + L I NV +E D G Y C N AG++S + T+ V
Sbjct: 2229 NYQPIDLEAEDARITRLSNDRRLTILNV-TENDEGQYSCRVKNDAGENSFDFKATVLVPP 2287
Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG--RXXX 983
+ K+ E TV L C + W+ + + I + +II G
Sbjct: 2288 TIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ 2347
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRK--LQDFEVKEKDVAILEV 1038
D G C + S V TIP+ + D+E ++ + ++
Sbjct: 2348 LKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC 2407
Query: 1039 EINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
+ + A + W + G KP ++ + + +KLY+ D +Y+CI +E+ T
Sbjct: 2408 PVYARPPAKITWLKAG---KPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGT 2464
Query: 1098 ----AEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147
+V+++ P P I+ R+ VN GN +T KG + W KDG+ I+
Sbjct: 2465 DKRDFKVSMLVAPSFDEPNIVRRI---TVNSGNPSTLHCP-AKGSPSPTITWLKDGNAIE 2520
Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP 1203
N + D +Q L+I + D G Y+C VG+ L V P + R
Sbjct: 2521 -PNDRYVFFDAGRQ-LQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGER-R 2577
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDT---EKFTLISDVKKRTLIIRKCT 1259
E + V + L + +DV W K I +DT + F I K+ +
Sbjct: 2578 EAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFL-SAR 2636
Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFP 1315
+ D YTC++ + A KL V PP I D I+ V + P
Sbjct: 2637 KSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSP 2696
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
P W+ + K ++ + + +L I + + AG Y +NN G A + V
Sbjct: 2697 HPKVYWLFDDKPLEP-DSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLV 2755
Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
+ P + + + + + C E++ + +Y+ + + S
Sbjct: 2756 RVTAPPHFEKEREEVVARVGDTMLLTC--NAESSVPLSSVYWHAHDESVQNGVITSKYAA 2813
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
+ ++ N++ + + AVNE I T +++K+I I++P K
Sbjct: 2814 NEKTLNVTNIQLDDEGFYYCTAVNEAGI-----TKKFFKLI---VIETPYFLDQQKLYPI 2865
Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
+ + L C G P P + + +DGK+L + Y CIA
Sbjct: 2866 ILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAE 2925
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
N G E +V + P +S E I + + GD + IE + W + K
Sbjct: 2926 NKAGRSEKDMMVEVLLPP--KLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGK- 2982
Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ + + S + I + + Y+ A N AG + + V P
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Score = 155 bits (375), Expect = 4e-37
Identities = 250/1241 (20%), Positives = 449/1241 (36%), Gaps = 107/1241 (8%)
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+ +N A F T L + DH T D++ + P
Sbjct: 1866 LTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTL 1925
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
++EG +I+L C P P W F ++ P E + V ++ H + + NV K+
Sbjct: 1926 EINEGEEIILTCDAEGNPTPTAKWDFNQGDL-PKEAVFV---NNNH----TVVVNNVTKY 1977
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y A N+ G+A I + ++T + + E + V S+ L V
Sbjct: 1978 HTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTE--SELTVNLTRSITLECDVDDAIG 2035
Query: 764 PTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
I+W N KP A + T + G I K D G Y N G+A +
Sbjct: 2036 VGISWTVNGKPFLAETDGVQTLAGGRFLHIV---SAKTDDHGSYACTVTNEAGVATKTFN 2092
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+ V+ PP +N E TV E ++ L VT P P +TW ++ + +++
Sbjct: 2093 LFVQ-------VPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSV 2145
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT---FVKHLQK 936
+G+ ++V + G Y C+A N G A ++ DV+ +T K ++
Sbjct: 2146 QVLSEGQQFKIVHAEI---AHKGSYICMAKNDVGT----AEISFDVDIITRPMIQKGIKN 2198
Query: 937 SYETEEGKTVILECQTSHTVSTK----WYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXX 991
+G + +C + K W N + I + I +
Sbjct: 2199 IVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTE 2258
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQD---FEVKEKDVAILEVEINSETA 1045
D G C VK+ K T+ P I +D V+ V +
Sbjct: 2259 NDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEP 2318
Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTSVHDEGEYSCILRDESCTAE---- 1099
D+ W +DGE I +N D G + +L I D G+Y+C + + + E
Sbjct: 2319 DITWFKDGEAIH-IENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVN 2377
Query: 1100 VTVVELPPEIITRLQNQKVNKGN-KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157
V V+ +P + + ++ N + + + A + W K G +Q ++ + +
Sbjct: 2378 VNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSAN 2437
Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCT-AILTVEEPSINFTLRLPEFILVPANT 1212
G QKL ++ D+ +Y+C E G K + + PS + + + N
Sbjct: 2438 G--QKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNP 2495
Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
+ +TW K + IE +++ R L I K DQ YTC+ +
Sbjct: 2496 STLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFD--AGRQLQISKTEGSDQGRYTCIATN 2553
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+ + L+ + P ++D ER + G L D + + EW + I +
Sbjct: 2554 SVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFCDSNS-TGVDVEWQKDGLTINQ 2612
Query: 1331 CKHTKPS---IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
S I S ++ +D+G Y + N G A + + D PS
Sbjct: 2613 DTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS----- 2667
Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN- 1446
+ + SS NI P I VV W+ + ++ L N
Sbjct: 2668 --ISDELSSANIQTIVPY---YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNG 2722
Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTC 1503
+ + V K K+ ++ P EK + + + + LTC
Sbjct: 2723 ETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTC 2782
Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
VP V W+ + ++ T + N Y C A N+ G
Sbjct: 2783 NAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGIT 2842
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+ + + + P ++ +G + G PPP +++ K+G +L E
Sbjct: 2843 KKFFKLIVIETPYFL--DQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEV 2900
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
+I S + I ++ +YT A N AG S ++ ++V P + + + +
Sbjct: 2901 DII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQA 2956
Query: 1680 RESVTIEWKPPLDDGGLELT---KYAIE-------KHEPDNNRWIKVADVDRDVETYCIQ 1729
+ +T+E P D G+ +T ++ + + D ++ + D ++Y
Sbjct: 2957 GDPLTLEC-PIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCI 3015
Query: 1730 KLNE--NCEYMFRVIAQNPVG-FSEALESEPIVIKTALDVP 1767
+N+ E +F+V P F ++ + IV T L++P
Sbjct: 3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIP 3056
Score = 154 bits (374), Expect = 6e-37
Identities = 197/794 (24%), Positives = 327/794 (41%), Gaps = 74/794 (9%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A++ G PT + P V+ + L+C V IP P+I W KG ++ N +
Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQ 843
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
+ L IT+ + +G +T +A N G+ S L + TG P P + +
Sbjct: 844 ----LADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMV-TGLVSPVLGHVPPEEQL 898
Query: 746 VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
+ +G+ + LS VV G P+P+I W K++KPV+ PT S+ L+ KDEG YT
Sbjct: 899 I-EGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYT 957
Query: 805 LKAENSEG----------IAETSAVITVE-----EPTEENAEPP--LFINRFQEITVKEK 847
A + G I + V E +PT + +N ++ E
Sbjct: 958 CIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEG 1017
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKC 906
I V V+ P P ITWY + I+P S T D L++ D SG Y C
Sbjct: 1018 FAIPCV--VSGTPPPIITWYLDGRPITPNSRDFTVTADN---TLIVRKADKSY-SGVYTC 1071
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHN 963
A+NSAG + + TI + + Q S+ + C V T +
Sbjct: 1072 QATNSAGDNEQ--KTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDD 1129
Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020
K G+ + ++G G C ++ +T T+ + T P
Sbjct: 1130 KPFTEGV----VNEDGSLTIPNVNEAHR---GTFTCHAQNAAGNDTRTVTLTVHTTPTIN 1182
Query: 1021 RKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ Q+ + D +LE + V +W +GE I + + + G L ++N
Sbjct: 1183 AENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG---ALVLQNV 1239
Query: 1080 SVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD 1134
+ + G + C + ++S + +TV E P+II+ + V KG T
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHE-KPKIISEVPGVVDVVKGFTIEIPCRATGVP 1298
Query: 1135 ALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAIL 1189
++R W K+G +++ + ++D L+IY+ D +D G Y+C E G S+ T +
Sbjct: 1299 EVIRTWNKNGIDLKMDEK-KFSVD-NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHV 1356
Query: 1190 TVEEPSINF-TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTLISD 1247
V+EP I + + +V + VE VTW+++ I DT+ + + SD
Sbjct: 1357 DVQEPPIILPSTQTNNTAVVGDRVELKCYVE-ASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSD 1304
TL+I+ + +D YTC + K+ L+V V+ P K D + IK
Sbjct: 1416 ---GTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
+L + P P W +N K + K + + D K L + K + TD+G+YK N
Sbjct: 1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDK-RKLHVFKAKITDSGVYKCVARN 1531
Query: 1365 NCGHADVEMNVTIL 1378
G V ++
Sbjct: 1532 AAGEGSKSFQVEVI 1545
Score = 153 bits (372), Expect = 1e-36
Identities = 255/1182 (21%), Positives = 445/1182 (37%), Gaps = 104/1182 (8%)
Query: 523 DGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C V G P+P I W + KP ++ + + L +R P+D G +
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWIKDD---KPVEEGPTIKIEGGGSLLRLRGGNPKDEGKY 956
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
TC+A + AG +ST + V+ E + + E +
Sbjct: 957 TCIAVSPAG--NSTLHINVQLIKKP---EFVYKPEGGIVFKPTISGMDEKHVAVVNS--- 1008
Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
V +G + C + P P I W G I P+ + +D + L +
Sbjct: 1009 THDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSR-DFTVTAD-----NTLIVRKAD 1062
Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
K G YT A N G+ ++I P + S + + + V G+
Sbjct: 1063 KSYSGVYTCQATNSAGDNEQKTTIRI----MNTPMISPGQSSFNMVVDDLFTIPCDVYGD 1118
Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
P+P ITW ++KP DG S+TI + G +T A+N+ G + +T
Sbjct: 1119 PKPVITWLLDDKPFTEGVVNEDG---SLTIPNVNEA-HRGTFTCHAQNAAGNDTRTVTLT 1174
Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
V NAE QE + I L P P W E I S+ I
Sbjct: 1175 VHTTPTINAEN-------QEKIALQNDDIVLECPAKALPPPVRLWTYEGEKID-SQLIPH 1226
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
E+ LV+ NV E ++G + C SN AG+ S +T+ EK + + +
Sbjct: 1227 TI-REDGALVLQNVKLE-NTGVFVCQVSNLAGEDSLSYTLTVH-EKPKIISEVPGVVDVV 1283
Query: 942 EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
+G T+ + C+ + V W N ++ MD ++ + D+G C
Sbjct: 1284 KGFTIEIPCRATGVPEVIRTWNKNGIDLK-MDEKKFSVD-NLGTLRIYEADKNDIGNYNC 1341
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-----SETADVVWERDGE 1054
+V ++ ++ + + E L + V VE+ S A V W R G
Sbjct: 1342 VVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGI 1401
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP---- 1106
I Y E G L I++ SV D Y+C + + AE VTV+ P
Sbjct: 1402 AIGTDTKGYVVESDG---TLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKD 1458
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+++T+ + + + + + + + W+ + + T D K+ KL +
Sbjct: 1459 PDVVTQ---ESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKR-KLHV 1514
Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF-ILVPANTDAYLTVEIPDE 1223
+ + D+G Y C N+ + + E + L ++ V A +T+ P
Sbjct: 1515 FKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS 1574
Query: 1224 TL---DVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
+ W +V+E +K+ TL +D TL + + Y CV +
Sbjct: 1575 GFPVPQINWVVDGTVVEPGKKYKGATLSND--GLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632
Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTK 1335
+ VE+ IV + + G D++L D Q W +N + + +
Sbjct: 1633 DIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQ 1692
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEI 1392
D +T K EN G Y R+ N+ G A+ + + +L+ P P + N I
Sbjct: 1693 IPSDGHRLYITDAKPENN--GKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLI 1750
Query: 1393 DSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
++ I + + + TGN + + ++ ++D + W+ ++++ + I+ L T S +
Sbjct: 1751 GNNPIIL---QCQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLR--IEKL-TGKSAQI 1803
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT-EPNEDIELTCIFGGVPQ 1510
A N+ + + +++ I +PT + T +E I L C +
Sbjct: 1804 SCTAENKA----GTASRDFF----IQNIAAPTFKNEGDQETIFRESETITLDCPV-SLGD 1854
Query: 1511 PKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
++TW + G L A + + Y C+A N G+V V +Q
Sbjct: 1855 FQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQV 1914
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
P I N + + G+E ++T EG P P W N L KE T V
Sbjct: 1915 LP--KIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDFNQGDL--PKEAVFVNNNHTVV 1970
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
+ + + H+ Y A+N G + + + V KP G
Sbjct: 1971 --VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESG 2010
Score = 145 bits (351), Expect = 3e-34
Identities = 245/1099 (22%), Positives = 431/1099 (39%), Gaps = 110/1099 (10%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+PP SK+ V G + LEC + I W + D + + +S
Sbjct: 2941 LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW---SRQFGKDGQLDMRAQSSSDK- 2996
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGE 750
S L I +Y+ +AVN G A + + T PP++ + + +
Sbjct: 2997 -SKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADT 3051
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTH-SITILKPKKVKDEGVYTLKA 807
++ + + G P P I+W + KP+ +P T GD I +KP + EG YT A
Sbjct: 3052 TLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQ---EGRYTCVA 3108
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
EN G AE + + +EPP + + + V E + V NP P + W
Sbjct: 3109 ENKAGRAEQDTYVEI-------SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWL 3161
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ E + S+ + + + L T + D G Y C+A+N AG+S + T DVE
Sbjct: 3162 KDGEPYT-SDLLQFSTKLSYLHLRETTL---ADGGTYTCIATNKAGES----QTTTDVEV 3213
Query: 928 VT--FVKHLQKSYETEEGKTVILECQ-TSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX 983
+ ++ ++ + +EG T ++ CQ T V W N KEI + I+
Sbjct: 3214 LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIRNA---- 3269
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
D G CI ++ + + L+ T P F F + E + A +E +I
Sbjct: 3270 ------TRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKI 3323
Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ + W + G + RG L I D G Y+C+ + +E
Sbjct: 3324 DGHPKPTISWLKGGRPFN--MDNIILSPRGDT--LMILKAQRFDGGLYTCVATNSYGDSE 3379
Query: 1100 ----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLT 1155
V V P T Q K G + + + +K G + N + T
Sbjct: 3380 QDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDA-VPNDSRHT 3438
Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210
I LKI +DAG+YSC E GN + A + +P+ F + V
Sbjct: 3439 IVNNYD-LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPT--FVRKGGNLYEVIE 3495
Query: 1211 NTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
N + + L ++W++ + +++++ D T I K D +Y C
Sbjct: 3496 NDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHIT--INKAKLSDGGKYICR 3553
Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY-----QAFPQPNDEWIV 1323
+ T+ + + + + PPKI ++ I + Y PQP+ W
Sbjct: 3554 ASNEAGTSDIDLILKILVPPKI---DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK 3610
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS- 1382
N I ++ + + + I+ V+ TD G Y N G A + ++ +L P
Sbjct: 3611 NGMDINMTD-SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEF 3669
Query: 1383 --PPGKPNIL-EIDSSSINICWDEPENTGNSTI-IYYVVEYQEID--TTEWISVKNITKT 1436
+P I E D+ ++ E+ + + + + + + +D T+ + + + +
Sbjct: 3670 DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRK 3729
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP- 1495
T Q N+ + A+N A E + +KV +I SP V +N +P
Sbjct: 3730 LTISQASLENAGL-YTCIALNR-----AGEASLEFKV----EILSPPVIDISRN-DVQPQ 3778
Query: 1496 ---NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKC 1550
N+ + C G P P + W ++GK++ + E + C
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 3838
Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
+A ND G E V+ + PV+++ +++ IK +G+ + G P P++ W K
Sbjct: 3839 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA---LGETITLFCNASGNPYPQLKWAKG 3895
Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
G+ L D K + + I LK++ YT +A N AGTS V++ V P
Sbjct: 3896 GS-LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEIN 3954
Query: 1670 EGPVIM--REISRESVTIE 1686
+ M R +++S+T++
Sbjct: 3955 RDGIDMSPRLPAQQSLTLQ 3973
Score = 141 bits (341), Expect = 6e-33
Identities = 241/1190 (20%), Positives = 427/1190 (35%), Gaps = 123/1190 (10%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLV 569
I ++K + K + STV C G P P ITWF+ I + + + N L
Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + DAG +TC A N+AG + ++ P +
Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEK--------------------- 2388
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+GIP + + + +++ C + A P I WL G+ + D+ + + +
Sbjct: 2389 -DGIPSDYESQ-------QNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS-ANGQ 2439
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747
+Y L+ T+ K YT +A N G + + + P ++ + + V
Sbjct: 2440 KLYLFKLRETDSSK-----YTCIATNEAGTDKRDFKVSMLVAPSFDEPNIV---RRITVN 2491
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
G L G+P PTITW K+ ++ D + + D+G YT A
Sbjct: 2492 SGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIA 2551
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
NS G + + V P P + R + + V E + +L V + W
Sbjct: 2552 TNSVGSDDLENTLEVIIP------PVIDGERREAVAVIEGFSSELFCDSNSTGV-DVEWQ 2604
Query: 868 RNNEIISPSETITQNF-----DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
++ I+ +F G+ + + + DSG Y C+ N AG+ AR
Sbjct: 2605 KDGLTINQDTLRGDSFIQIPSSGKKMSFLSAR---KSDSGRYTCIVRNPAGE----ARKL 2657
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVI------LECQTSHTVSTK--WYHNKKEISGMDHRE 974
D V + + +T++ + C S + K W + K + D
Sbjct: 2658 FDF-AVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLE-PDSAA 2715
Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEK 1031
G C ++ + LV P F ++ ++ +
Sbjct: 2716 YELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVG 2775
Query: 1032 DVAILEVEINSET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
D +L S + V W E + + + + + L + N + DEG Y C
Sbjct: 2776 DTMLLTCNAESSVPLSSVYWHAHDESV--QNGVITSKYAANEKTLNVTNIQLDDEGFYYC 2833
Query: 1090 ILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
+E+ ++ V+E P + + + + G + T + T + + KDG
Sbjct: 2834 TAVNEAGITKKFFKLIVIE-TPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204
+ S+ + + L I + + G Y+C N + + + E
Sbjct: 2893 RLNESDEVDII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948
Query: 1205 FILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
+I V LT+E P E + +TW ++ + S K + L I + T +
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK-LYIMQATPE 3007
Query: 1262 DQCEYTCVLL-DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPND 1319
D Y+C+ + DA + V PPKI D I + + + + P P
Sbjct: 3008 DADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEI 3067
Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W ++ K I + P + K SL I ++ G Y EN G A+ + V I
Sbjct: 3068 SWFLDGKPILE----MPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEI 3123
Query: 1378 LDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
+ P ++ ++ I E GN + ++ E T++ + T
Sbjct: 3124 SEPPRVVMASEVMRVVEGRQTTI---RCEVFGNPEPVVNWLKDGEPYTSDLLQF----ST 3176
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
+ S +L+ + Y + + S+TT +V + P +E + + +
Sbjct: 3177 KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV-----LVPPRIEDEERVLQGKEG 3231
Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+ C G P P VTW R+GK+++ R Y CIA N+
Sbjct: 3232 NTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIR------NATRADEGKYSCIASNEA 3285
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G ++ + KP T + G+ + I+G P P + W K G D
Sbjct: 3286 GTAVADFLIDVFTKP--TFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMD 3343
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
NI + + I + +R YT A+N+ G S + + VY KP
Sbjct: 3344 ---NIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390
Score = 138 bits (335), Expect = 3e-32
Identities = 248/1116 (22%), Positives = 432/1116 (38%), Gaps = 104/1116 (9%)
Query: 599 IVEAPLSDHGSEMT-VXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLEC 655
I +A ++G M V D+LE PP F + Q + + I+L+C
Sbjct: 1702 ITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE--PPVFVEPVFEANQKLIGNNPIILQC 1759
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P+P + W G ++ + S + + S+L+I + + + A N+
Sbjct: 1760 QVTGNPKPTVIWKIDGNDV----DKSWLFDESL----SLLRIEKLTG-KSAQISCTAENK 1810
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKP 774
G AS ++ P E + I R+ E++ L V +G+ + ITW K P
Sbjct: 1811 AGTASRDFFIQ---NIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ--ITWMKQGLP 1865
Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPP 833
+ D +TIL + E +YT A N+ G +++ V+ P +NA
Sbjct: 1866 LTENDAIFTLDNTRLTILNANR-DHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVT 1924
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
L IN +EI L NP P+ W N + P E + F N +V+
Sbjct: 1925 LEINEGEEII--------LTCDAEGNPTPTAKWDFNQGDL-PKEAV---FVNNNHTVVVN 1972
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVILECQT 952
NV ++ +G YKC A+N G++ V + K F L +S T +++ LEC
Sbjct: 1973 NV-TKYHTGVYKCYATNKVGQAVKTINVHVRT-KPRFESGLTESELTVNLTRSITLECDV 2030
Query: 953 SHT--VSTKWYHNKKE-ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ET 1006
V W N K ++ D + + GR D G C V ++ T
Sbjct: 2031 DDAIGVGISWTVNGKPFLAETDGVQTLAGGR--FLHIVSAKTDDHGSYACTVTNEAGVAT 2088
Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065
T + + P + + ++ V E + +L E+ + VV W +DG +P +
Sbjct: 2089 KTFNLFVQVPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG---RPVGDLKSV 2145
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK-------V 1118
+ ++ I + + +G Y C+ +++ TAE++ +IITR QK
Sbjct: 2146 QVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEIS---FDVDIITRPMIQKGIKNIVTA 2202
Query: 1119 NKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDLDDAG 1174
KG F+ + + W ++ I + ++T ++L I + +D G
Sbjct: 2203 IKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEG 2262
Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETL------- 1225
+YSC V N E S +F T+ +P I++ VE TL
Sbjct: 2263 QYSCRVKND-------AGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGK 2315
Query: 1226 ---DVTWYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-- 1278
D+TW+K IE+ ++ L I + E D +YTC ++ + +
Sbjct: 2316 PEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQD 2375
Query: 1279 LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
+ V V+ P D +Y ++ V + A P W+ K ++ K K S
Sbjct: 2376 VNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS 2435
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSS 1396
+ + L + K+ TD+ Y N G + V++L PS +PNI+ I +S
Sbjct: 2436 ANGQ--KLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPS-FDEPNIVRRITVNS 2492
Query: 1397 IN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
N P S I ++ + I+ + + + Q I + + R+ A
Sbjct: 2493 GNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGR-QLQISKTEGSDQGRYTCIA 2551
Query: 1456 VNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
N V D T E VI + ++ V ++ ++E D T + + +
Sbjct: 2552 TNSVGSDDLENTLEVIIPPVIDGERREAVAV---IEGFSSELFCDSNSTGVDVEWQKDGL 2608
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
T +D + + + Y CI N GE + P I
Sbjct: 2609 TINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSI 2668
Query: 1574 T--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVI 1630
+ +S+ +I Q + V+ G P P+V W + LE D Y +T +T +
Sbjct: 2669 SDELSSANI-QTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET--L 2725
Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+I + H+ YT EA N G + + ++V P
Sbjct: 2726 KIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPP 2761
Score = 132 bits (319), Expect = 3e-30
Identities = 240/1100 (21%), Positives = 415/1100 (37%), Gaps = 121/1100 (11%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
DI+E PP+ P+ Y + + L C + P+P++ W FKG ++ D V +S
Sbjct: 606 DIME--PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDS 663
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
L I + EGTY A+++ G+A L + T PP+V M+V
Sbjct: 664 ------KFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLAT----PPKVEIIQNKMMV 713
Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
+G+ V + + G P P I W KN K + + + I+ K +D G Y+
Sbjct: 714 GRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKD-EDAGAYSC 772
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
EN G A ++V P I + V + + L P P I
Sbjct: 773 VGENMAGKDVQVANLSV-------GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIE 825
Query: 866 WYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W + N +++ + TQ DG L+IT+ E D G + C+A N+ G+ S + +
Sbjct: 826 WQKGNVLLATLNNPRYTQLADG---NLLITDAQIE-DQGQFTCIARNTYGQQSQSTTLMV 881
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGR 980
+ H+ + EG+ + L C + S W + K + + I EG
Sbjct: 882 TGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVE--EGPTIKIEGG 939
Query: 981 XXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD---FE-----VK 1029
D G CI V ST+ + + I PEF+ K + F+ +
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 1030 EKDVAILE---------------VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
EK VA++ V + + W DG I P N DF L
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITP--NSRDFTVTAD-NTL 1056
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132
+R G Y+C + + E T + + + N F I
Sbjct: 1057 IVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVY 1116
Query: 1133 GD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCT 1186
GD ++ W D + F+ + + DG L I + + G ++C GN T
Sbjct: 1117 GDPKPVITWLLD--DKPFTEGV-VNEDG---SLTIPNVNEAHRGTFTCHAQNAAGNDTRT 1170
Query: 1187 AILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV---TW-YKKKSVIEDTEK 1241
LTV P+IN E I + N D + +E P + L W Y+ + +
Sbjct: 1171 VTLTVHTTPTIN--AENQEKIAL-QNDD--IVLECPAKALPPPVRLWTYEGEKIDSQLIP 1225
Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
T+ D L+++ ++ + C + L + + + V E P I + +
Sbjct: 1226 HTIRED---GALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
+G + + P+ W N I K K S+D+ +L I + + D G Y
Sbjct: 1283 VKGFTIEIPCRATGVPEVIRTWNKNG-IDLKMDEKKFSVDN-LGTLRIYEADKNDIGNYN 1340
Query: 1360 LRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYV 1416
+ N G + + +V + + P P + N + + + C+ E + T
Sbjct: 1341 CVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG 1400
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+ DT ++ + T IQ+ + + A N ++A+ ++
Sbjct: 1401 IAI-GTDTKGYVVESDGTLV---IQSASVEDATIYTCKASNPAGKAEAN--------LQV 1448
Query: 1477 TKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYEN 1531
T I SP ++ P + + + + L C P P+++WY + K L KT+ T ++
Sbjct: 1449 TVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD 1508
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----G 1587
+ YKC+A N GE S Q + ++ ++ ++ K K KV G
Sbjct: 1509 KRKLHVFKAKITDSGVYKCVARNAAGEGSKS----FQVEVIVPLNLDESKYKKKVFAKEG 1564
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+E + + G P P++ W +G +E K+Y T + + + Y
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCV 1624
Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666
A + ++V L V P
Sbjct: 1625 AQSKGNILDIDVELSVLAVP 1644
Score = 125 bits (302), Expect = 3e-28
Identities = 172/797 (21%), Positives = 313/797 (39%), Gaps = 68/797 (8%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
I T + PKA G +I+L+C ++ P P + W +G++ VP+++ + +
Sbjct: 3392 IDETIDQTPKAV---AGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN----- 3442
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
LKI +V G Y+ +AVN G + ++ G+ P V + V + ++
Sbjct: 3443 -YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEV-IGK--PTFVRKGGNLYEVIENDT 3498
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+ + V P P+I+W + +KPV S S + K+ D G Y +A N
Sbjct: 3499 ITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEA 3558
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G ++ ++ + P + + I I + TI L ++ P P + W +N
Sbjct: 3559 GTSDIDLILKILVPPK--IDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGM 3613
Query: 872 IISPSET---ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
I+ +++ + QN + IE V D G Y C A+N GK+SH + + +
Sbjct: 3614 DINMTDSRVILAQNNETFGIENV-----QVTDQGRYTCTATNRGGKASHDFSLDV-LSPP 3667
Query: 929 TFVKHLQKSYETEEGKTVILECQ-------TSHTVSTKWYHNKKEISG--MDHREIIQEG 979
F H + EG T+ L C + W + + + G D+ +I +G
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVA 1034
R + G+ CI ++ E S V+ P I R +V
Sbjct: 3728 R--KLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPT 3785
Query: 1035 ILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
I+ + + W ++G+ + +N ++G + ++ +R S H G++SC+ +
Sbjct: 3786 IMRCAVTGHPFPSIKWLKNGKEVTDDEN-IRIVEQGQVLQI-LRTDSDH-AGKWSCVAEN 3842
Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS 1149
++ E+ + V PP + + N G T + ++W K GS I F
Sbjct: 3843 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLI-FD 3901
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPE 1204
+ I K +L I D G+Y+C+ N+ T+ +V P IN +
Sbjct: 3902 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD-GIDM 3960
Query: 1205 FILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+PA L + + + W ++ T T+ SD + I + D
Sbjct: 3961 SPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASD--STFIQINNVSLSD 4018
Query: 1263 QCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ YTC + + L V+VV+ P ++ ++ G + + +P P
Sbjct: 4019 KGVYTCYAENVAGSDNLMYNVDVVQAP--VISNGGTKQVIEGELAVIECLVEGYPAPQVS 4076
Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
W+ N ++ + + LTI + + D+GIY N G A + +L
Sbjct: 4077 WLRNGNRVETGVQGVRYV-TDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 4135
Query: 1381 PS-PPGKPNILEIDSSS 1396
P P +L S S
Sbjct: 4136 PKIITSTPGVLTPSSGS 4152
Score = 118 bits (285), Expect = 3e-26
Identities = 204/945 (21%), Positives = 362/945 (38%), Gaps = 86/945 (9%)
Query: 651 ILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
I LEC + IP+PD+ W G +I + D + +A ++ I NV+ +G YT
Sbjct: 3592 IYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNE------TFGIENVQVTDQGRYT 3645
Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILS-----AQVVGNPR 763
A NR G+AS L + + PP+ I + I R+G+++ L+ A+ + +
Sbjct: 3646 CTATNRGGKASHDFSLDVLS----PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 764 PTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++W K+++ + T + D +TI + +++ G+YT A N G A +
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQAS-LENAGLYTCIALNRAGEASLEFKV 3760
Query: 821 TVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
+ P P + I+R Q + TI A VT +P PSI W +N + ++ E
Sbjct: 3761 EILSP------PVIDISRNDVQPQVAVNQPTIMRCA-VTGHPFPSIKWLKNGKEVTDDEN 3813
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
I G+ ++++ T+ D +G + CVA N AG + +DV V +
Sbjct: 3814 IRIVEQGQVLQILRTDSDH---AGKWSCVAENDAGVKE--LEMVLDVFTPPVVSVKSDNP 3868
Query: 939 ETEEGKTVILECQTSHTV--STKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVG 995
G+T+ L C S KW I D I +G DVG
Sbjct: 3869 IKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKG--ARLDIPHLKKTDVG 3926
Query: 996 VIKC-IVKDQETSTMLVVKETI--PEFIRKLQDFEVK---EKDVAILEVEINSETADVVW 1049
C + TS V + + PE R D + ++ + + + + W
Sbjct: 3927 DYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRW 3986
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL 1105
+G + + I N S+ D+G Y+C + ++ V VV+
Sbjct: 3987 TLNGTALTHSTPGITVASDSTF--IQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQA 4044
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS-NHIQLTIDGKKQKL 1163
P +I+ ++V +G A E + A V W ++G+ ++ ++ DG+ L
Sbjct: 4045 P--VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM--L 4100
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAY-LTVEI 1220
I + D+G Y C N +A T+E + +L P++ + L +
Sbjct: 4101 TIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV 4160
Query: 1221 ---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
PD ++W + I+D E I TL I K E+ Y C +
Sbjct: 4161 RGYPDPI--ISWTLNGNDIKDGENGHTIG--ADGTLHIEKA-EERHLIYECTAKNDAGAD 4215
Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
T + V+ + P R G++ + + ++ W N + +
Sbjct: 4216 TLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLI 4274
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
S D K + ++ +D G Y N G+A + N+ + P +P +
Sbjct: 4275 FSEDYKLIKILSTRL--SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG 4332
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAY 1454
W E I +Y + E+ T + TK ++ I ++ + + +
Sbjct: 4333 DQVTLWCEASGVPQPAITWY--KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCK 4390
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
A N V + E + +I P V N++T P + + L+C G+P+P ++
Sbjct: 4391 AENWV--ASTEEDIDLIVMIP------PEVVPERMNVSTNPRQTVFLSCNATGIPEPVIS 4442
Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGE 1558
W RD Y+ Y CIA +D G+
Sbjct: 4443 WMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ 4487
Score = 115 bits (277), Expect = 3e-25
Identities = 167/808 (20%), Positives = 317/808 (39%), Gaps = 71/808 (8%)
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957
D+G+Y+C ++ G S RV ++ G+ L C T V
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFG--VRNVSVPLGEAAFLHCSTRSAGEVE 550
Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKE 1014
+W + + E + D GV +C+ ++ T M +
Sbjct: 551 IRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608
Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
P QD ++ L E + +V W G + N Y ++ +
Sbjct: 609 EPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLL---NDYKYQVGQDSKF 665
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIEL 1130
LYIR+ + HDEG Y C ++ A T ++ PP++ V +G++ +FE +
Sbjct: 666 LYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKT 725
Query: 1131 TKGDA--LVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
+G +RWFK+G + I+ ++I++ + +L I +DAG YSC VG +
Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKIN----EGQLHIMGAKDEDAGAYSC-VGENMAGK 780
Query: 1188 ILTVEEPSINFTLRLPEFILVP----ANTDAYLTVE---IPDETLDVTWYKKKSVIE--D 1238
+ V S+ R+P I P N + +T++ + ++ W K ++ +
Sbjct: 781 DVQVANLSVG---RVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLN 837
Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIVDY 1293
++T ++D L+I +DQ ++TC+ + ++STT + +V P +
Sbjct: 838 NPRYTQLAD---GNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS--PVLGHV 892
Query: 1294 EREYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
E ++ G D+TL V P+P+ WI + K +++ K I+ + L ++
Sbjct: 893 PPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIK--IEGGGSLLRLRGGNP 950
Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKP----SPPG----KPNILEIDSSSINICWDEP 1404
D G Y + G++ + +NV ++ KP P G KP I +D + +
Sbjct: 951 KDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTH 1010
Query: 1405 E-NTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRA---YA-VNE 1458
+ G I VV W + + IT N+ +A Y+ V
Sbjct: 1011 DVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYT 1070
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
++++ E I+ + +P + + ++ + C G P+P +TW D
Sbjct: 1071 CQATNSAGDNEQKTTIR--IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128
Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
K + + C A N G + + + P I N+
Sbjct: 1129 DKPF--TEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ + D+ ++ + +PPP +W G K+ D + T + + ++ +K
Sbjct: 1187 E--KIALQNDDIVLECPAKALPPPVRLWTYEGEKI--DSQLIPHTIREDGALVLQNVKLE 1242
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ + + SN AG S+ TL V++KP
Sbjct: 1243 NTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270
Score = 104 bits (250), Expect = 6e-22
Identities = 120/542 (22%), Positives = 223/542 (41%), Gaps = 36/542 (6%)
Query: 1227 VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
+TWY + + ++ FT+ +D TLI+RK + YTC ++ + K + +
Sbjct: 1032 ITWYLDGRPITPNSRDFTVTAD---NTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
P I + + + T+ D P+P W+++ K + + ++ S
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTE------GVVNEDGS 1142
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
LTI V G + +N G+ + +T+ P+ + N +I + +I + P
Sbjct: 1143 LTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE-NQEKIALQNDDIVLECP 1201
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDI 1461
+ + E ++ID+ + I +QN+K ++ F N E +
Sbjct: 1202 AKALPPPVRLWTYEGEKIDS-QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL 1260
Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
S E K+I E P V +K T IE+ C GVP+ TW ++G
Sbjct: 1261 SYTLTVHEKPKIISEV----PGVVDVVKGFT------IEIPCRATGVPEVIRTWNKNGID 1310
Query: 1522 LKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
LK K + +N Y C+ N+ G + + V +Q+ P+I S +
Sbjct: 1311 LKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQT 1370
Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
VGD + +E PP V W++ G + D + + + T VI+ ++
Sbjct: 1371 -NNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE--D 1427
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-EL 1698
++ YT +ASN AG + + + V P + V+ +E +ES P+ L ++
Sbjct: 1428 ATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQI 1487
Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP 1757
+ Y +K D+ K +D R + + K +++ +A+N G S++ + E
Sbjct: 1488 SWYLNDKPLIDDKTSWKTSDDKRKLHVF---KAKITDSGVYKCVARNAAGEGSKSFQVEV 1544
Query: 1758 IV 1759
IV
Sbjct: 1545 IV 1546
Score = 86.2 bits (204), Expect = 2e-16
Identities = 119/600 (19%), Positives = 229/600 (38%), Gaps = 57/600 (9%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++ G P F ++V G D+ L C + + I W+ GE+I+ ++
Sbjct: 425 VIVGGPRAFMSPIHQEFV--GRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDT- 481
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
SV I + G Y ++ G S+ K + +E P I ++++ V
Sbjct: 482 -----SVWTIPELSLKDAGEYECRVISNNGNYSV----KTRVETRESPPEIFGVRNVSVP 532
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
GE+ L I W + V P T+ + D GVY A
Sbjct: 533 LGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMA 592
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N+ G++ + + EP P Q++ + + L +P P + WY
Sbjct: 593 RNAGGMSTRKMRLDIMEPPSVKVTP-------QDVYFNMREGVNLSCEAMGDPKPEVHWY 645
Query: 868 -RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ +++ + G++ + + + D G Y+C A + AG+ AR T D+
Sbjct: 646 FKGRHLLNDYKYQV----GQDSKFLYIRDATHHDEGTYECRAMSQAGQ----ARDTTDLM 697
Query: 927 KVT--FVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRX 981
T V+ +Q G V EC+T +W+ N K++ D I EG+
Sbjct: 698 LATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ- 756
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKLQDFEVK-EKDVAILE 1037
D G C+ ++ + V + +P I V E+ V +
Sbjct: 757 --LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQC 814
Query: 1038 VEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093
+ + ++ W++ ++ N +Y G+ L I + + D+G+++CI R+
Sbjct: 815 LAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGN---LLITDAQIEDQGQFTCIARNTYG 871
Query: 1094 -ESCTAEVTVVELPPEIITRL-QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149
+S + + V L ++ + +++ +G T + G + W KD ++
Sbjct: 872 QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG 931
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
I+ I+G L++ + D G+Y+C + + L + I + PEF+ P
Sbjct: 932 PTIK--IEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLI----KKPEFVYKP 985
Score = 85.8 bits (203), Expect = 3e-16
Identities = 108/505 (21%), Positives = 186/505 (36%), Gaps = 47/505 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V EG ++EC + P P ++WL G + V +D M L I +
Sbjct: 4055 VIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM----LTIIEARSLD 4109
Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESVILSAQVVGNPR 763
G Y A N G A L++ P++I ++ G L V G P
Sbjct: 4110 SGIYLCSATNEAGSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPD 4165
Query: 764 PTITWCKNNKPVKALPTKSDGDT-HSI----TILKPKKVKDEGVYTLKAENSEGIAETSA 818
P I+W N +K DG+ H+I T+ K + +Y A+N G
Sbjct: 4166 PIISWTLNGNDIK------DGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGAD---- 4215
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
T+E P + P + + + I E GT ++ + +W +N + PS
Sbjct: 4216 --TLEFPVQTIVAPKISTSGNRYINGSE-GTETVIKCEIESESSEFSWSKNGVPLLPSNN 4272
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
+ + D + I+++ T + D G+Y C A+N AG ++ + ++V + ++
Sbjct: 4273 LIFSEDYKLIKILSTRLS---DQGEYSCTAANKAGNATQ--KTNLNVGVAPKIMERPRTQ 4327
Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
+G V L C+ S + WY + + ++ E + GV
Sbjct: 4328 VVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT-KKKSVIFSSISPSQAGV 4386
Query: 997 IKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD 1052
C ++ ST + ++ PE + + + + L V+ W RD
Sbjct: 4387 YTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRD 4446
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEI 1109
I KY L IRN D+G Y CI + ++ T +V P +
Sbjct: 4447 SNIAIQNNEKYQILG----TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGD 1134
+ + KG E + +GD
Sbjct: 4503 PAPIWVECDEKGKPKKTEYMIDRGD 4527
Score = 75.8 bits (178), Expect = 3e-13
Identities = 109/530 (20%), Positives = 199/530 (37%), Gaps = 41/530 (7%)
Query: 1165 IYDCDLDDAGEYSCEV----GN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + L DAGEY C V GN S T + T E P F +R + VP A+L
Sbjct: 486 IPELSLKDAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCS 542
Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276
+++ W + + + + + TL I T D Y C+ +A ST
Sbjct: 543 TRSAGEVEIRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMST 600
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
K++++++E PP + ++ V L + P+P W + + K
Sbjct: 601 RKMRLDIME-PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHL--LNDYKY 657
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
+ S L I+ + D G Y+ R + G A ++ + P N + +
Sbjct: 658 QVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGD 717
Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ + I ++ I ++I I + Q I K + +
Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIK---INEGQLHIMGAKDEDAGAYSCVG 774
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
N + +V + + PT+ + + + L C+ G+P P++ W
Sbjct: 775 ENMAG--------KDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW 826
Query: 1516 YRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQ 1569
+ L T + T + CIA N +G+ T V G+
Sbjct: 827 QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS 886
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
+ + E+ Q + D L V+ G P P ++W K+ +E I + S+
Sbjct: 887 PVLGHVPPEE--QLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGP--TIKIEGGGSL 942
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMR 1676
+R++ KYT A + AG S++ + +++ KP KPEG ++ +
Sbjct: 943 LRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFK 992
Score = 66.1 bits (154), Expect = 3e-10
Identities = 55/236 (23%), Positives = 101/236 (42%), Gaps = 19/236 (8%)
Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
I+ LSD G E + ++ G+ P ++P+ Q V +G + L C
Sbjct: 4284 ILSTRLSDQG-EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 4342
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--RE 716
+P+P I W +K E++ + + E+ SV+ +++ Q G YT A N
Sbjct: 4343 GVPQPAITW-YKDNELLTNTGVD---ETATTKKKSVI-FSSISPSQAGVYTCKAENWVAS 4397
Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
E + +++ I PP+V+ ++ ++V LS G P P I+W +++
Sbjct: 4398 TEEDIDLIVMI------PPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAI 4451
Query: 777 ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
K G T +I + P D+G Y A++ G + + V +P++ A
Sbjct: 4452 QNNEKYQILGTTLAIRNVLP---DDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPA 4504
Score = 64.1 bits (149), Expect = 1e-09
Identities = 125/609 (20%), Positives = 232/609 (38%), Gaps = 70/609 (11%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G+ +C++E + +W + + PS + ++ +D + ++ + D G ++
Sbjct: 4241 EGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNL-IFSEDYKLIKILSTRL--SDQGEYS 4296
Query: 583 CVAKNAAGFASSTTEL-------IVEAPLSD---HGSEMTVXXXXX-----XXXXXXXAD 627
C A N AG A+ T L I+E P + G ++T+ +
Sbjct: 4297 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 4356
Query: 628 IL--EGIPPTFSKKPKA---QYVDEGSDILLECRL---VAIPEPDIAWLFK-GEEIVPDE 678
+L G+ T + K K+ + + C+ VA E DI + E+VP+
Sbjct: 4357 LLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPER 4416
Query: 679 -NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737
N+S + + C+ I + N E L L I+ +
Sbjct: 4417 MNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGF 4476
Query: 738 IEPLKSMIVRQGESVILSAQVVGNP--RPTITW--C-KNNKPVKALPTKSDGDT--HSIT 790
+ G+ + +V P RP W C + KP K GDT +
Sbjct: 4477 YHCIAKS--DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQ 4534
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+L K V+D + A +S + + +A P FI + + T +
Sbjct: 4535 LLPWKDVEDSSLNGSIAYRCMPGPRSSRTVLL------HAAPQ-FIVKPKNTTAAIGAIV 4587
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
+L P P+ITW ++ ++I S+ F+ L +T ++S DSG+Y C+A N
Sbjct: 4588 ELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT-LNSTSDSGEYTCMAQN 4641
Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN----KKE 966
S G S+ A + +D + K S + E +++ W +N K
Sbjct: 4642 SVGSSTVSAFINVDNNILPTPK--PSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 4699
Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRKL 1023
++G+ + G D+ + C V+++ + + E +PE ++ +
Sbjct: 4700 LAGI---HFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPHLTSAFEGVPE-VKTI 4755
Query: 1024 QDFEVKEKDVAILEVEINSE--TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
EV D +L+ E+ S+ T VVW ++ + + Y L + N
Sbjct: 4756 DKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPN----NSLVLLNVEK 4811
Query: 1082 HDEGEYSCI 1090
+DEG Y C+
Sbjct: 4812 YDEGVYKCV 4820
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 31/294 (10%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F KPK G+ + L C P P I W G+ ++ D +A S
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAY--------S 4620
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
LK+T G YT +A N G +++ + + P+ K++ +VI
Sbjct: 4621 HLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV------AVI 4674
Query: 754 LSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
+ +TW N P+ K L + S+ IL +K D +YT K N
Sbjct: 4675 TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITWYRN 869
+ E E + ++ V ++ L VT +P+ + + W +N
Sbjct: 4735 RRHSIPHLTSAFEGVPE--------VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN 4786
Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
++ + + I + N LV+ NV+ + D G YKCVASNS GK+ ++ +
Sbjct: 4787 DQKMLDDDAI---YVLPNNSLVLLNVE-KYDEGVYKCVASNSIGKAFDDTQLNV 4836
Score = 57.6 bits (133), Expect = 9e-08
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 19/271 (7%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
PQ I K+ G V L G P PTITW K+ K ++ + +T+
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL--- 4626
Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
D G YT A+NS G + SA I V+ +P IT E+ + +
Sbjct: 4627 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERN--QAYS 4684
Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
R +TW N + P +F N LVI + S + GD + +
Sbjct: 4685 R-------GLTW-EYNGVPMPKNLAGIHF-MNNGSLVILDT-SSLKEGDLELYTCKVRNR 4734
Query: 915 SSHG-ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDH 972
H +T E V VK + K E G +V+L+C+ TS ++T K + +D
Sbjct: 4735 RRHSIPHLTSAFEGVPEVKTIDK-VEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDD 4793
Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
+ I D GV KC+ +
Sbjct: 4794 -DAIYVLPNNSLVLLNVEKYDEGVYKCVASN 4823
Score = 56.0 bits (129), Expect = 3e-07
Identities = 61/321 (19%), Positives = 120/321 (37%), Gaps = 22/321 (6%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P + P GS L C + P+P I+W G +I EN I +D
Sbjct: 4136 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGEN-GHTIGAD----- 4189
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
L I ++ + Y A N G +L ++ K + +G
Sbjct: 4190 GTLHIEKAEE-RHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING---SEGTET 4245
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ + + + +W KN P+ + + + + ++ D+G Y+ A N G
Sbjct: 4246 VIKCE-IESESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAG 4304
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A + V P + R + V + + L + P P+ITWY++NE+
Sbjct: 4305 NATQKTNLNV-------GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNEL 4357
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
++ + + + + ++ +++ S +G Y C A N + + + + +
Sbjct: 4358 LT-NTGVDETATTKKKSVIFSSI-SPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 4415
Query: 933 HLQKSYETEEGKTVILECQTS 953
+ S T +TV L C +
Sbjct: 4416 RMNVS--TNPRQTVFLSCNAT 4434
Score = 54.8 bits (126), Expect = 6e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 24/347 (6%)
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
TI ++ DAG Y+ R+ +N G+ V+ V + P P I + + S+ + E
Sbjct: 485 TIPELSLKDAGEYECRVISNNGNYSVKTRVETRESP-----PEIFGVRNVSVPL--GEAA 537
Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA-VNEVDISDA 1464
ST VE + T +V N T+ + N + RA A V E +A
Sbjct: 538 FLHCSTRSAGEVEIRW--TRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNA 595
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
+ + ++ ++ P+V+ +++ E + L+C G P+P+V WY G+ L
Sbjct: 596 GGMST--RKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLN 653
Query: 1525 --AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
++ Y+C A + G+ + + + P + I I+
Sbjct: 654 DYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEI----IQN 709
Query: 1583 KHKVGDEWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
K VG V+ I G P P++ W+KNG L +Y K + I K
Sbjct: 710 KMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDY---IKINEGQLHIMGAKDED 766
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
+ Y+ N AG L V P+ E P +R VT++
Sbjct: 767 AGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQ 813
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C N G+ E + + + + PV + QK + ++ + G P P VIW
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+GN + DK + E S++RI++L S++ + A N AGT+S + ++ P+
Sbjct: 1773 IDGNDV--DKSW--LFDESLSLLRIEKL-TGKSAQISCTAENKAGTASRDFFIQNIAAPT 1827
Query: 1668 -KPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
K EG I RES TI P+ G ++T
Sbjct: 1828 FKNEGD--QETIFRESETITLDCPVSLGDFQIT 1858
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
K +G EC VEGYP PQ++W R ++ Y D + T++ E D+
Sbjct: 4053 KQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII--EARSLDS 4110
Query: 579 GTFTCVAKNAAGFASS--TTELIV 600
G + C A N AG A T E++V
Sbjct: 4111 GIYLCSATNEAGSAQQAYTLEVLV 4134
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
PI + + +T G V+ +C VE P +TWFR+ I D + Y + + TL
Sbjct: 1362 PIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAI--GTDTKGYVVESD-GTL 1418
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
VI+ EDA +TC A N AG A + ++ V A
Sbjct: 1419 VIQSASVEDATIYTCKASNPAGKAEANLQVTVIA 1452
Score = 48.0 bits (109), Expect = 7e-05
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ T E S P V +G C+V G P P + W + +P +
Sbjct: 3116 EQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDG---EPYTSDLL 3172
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ ++ L +RE D GT+TC+A N AG + +TT++ V P
Sbjct: 3173 QFST-KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C A N G + + P I + + HK GD+ + G+P P + WY
Sbjct: 4295 YSCTAANKAGNATQKTNLNVGVAPKI-MERPRTQVVHK-GDQVTLWCEASGVPQPAITWY 4352
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
K+ L N T +K SVI + S + YT +A N ++ ++ L V P
Sbjct: 4353 KDNELLTNTGVDETATTKKKSVI-FSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 4410
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T+ +AP +E+ R + G V C+ G P+P ITW++ ++ + +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET--A 4367
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+++ + P AG +TC A+N +LIV P
Sbjct: 4368 TTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIP 4409
Score = 45.2 bits (102), Expect = 5e-04
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 8/92 (8%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F+ K + G+ V+ C G P P ITW + +I+ S+ F++ Y + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-FEIAY-----SHL 4622
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ D+G +TC+A+N+ G SST +
Sbjct: 4623 KVTLNSTSDSGEYTCMAQNSVG--SSTVSAFI 4652
Score = 44.8 bits (101), Expect = 7e-04
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V C+ G P+P++ W+ + + +Q+ D L IR+ D GT+ C A
Sbjct: 628 VNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSK---FLYIRDATHHDEGTYECRAM 684
Query: 587 NAAGFASSTTELIVEAP 603
+ AG A TT+L++ P
Sbjct: 685 SQAGQARDTTDLMLATP 701
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 508 MAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+AP F E +R G+ C +G P P ITW + I+P+ D +++D
Sbjct: 2475 VAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPN-DRYVFFDAGR- 2532
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGF--ASSTTELIV 600
L I + D G +TC+A N+ G +T E+I+
Sbjct: 2533 -QLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVII 2568
Score = 41.1 bits (92), Expect = 0.008
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 25/102 (24%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
+ VF KPT E VE G + + EC+++G+P+P I+W +K +
Sbjct: 3294 IDVFTKPTFETHETTFNIVE---------GESAKIECKIDGHPKPTISW------LKGGR 3338
Query: 555 DFQMYYDDDNVA------TLVIREVFPEDAGTFTCVAKNAAG 590
F M DN+ TL+I + D G +TCVA N+ G
Sbjct: 3339 PFNM----DNIILSPRGDTLMILKAQRFDGGLYTCVATNSYG 3376
Score = 40.3 bits (90), Expect = 0.015
Identities = 95/459 (20%), Positives = 174/459 (37%), Gaps = 45/459 (9%)
Query: 1002 KDQETSTMLVVKETIPE---FIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEII 1056
K Q T L ++ +P+ F + + +K +A ++ +N S+ +W E
Sbjct: 4456 KYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQK-IATRKLIVNKPSDRPAPIWVECDEKG 4514
Query: 1057 KPKKNKYDFEKRGH-------IRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
KPKK +Y ++ + + ++S++ Y C+ S + ++ P+
Sbjct: 4515 KPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPGPRS--SRTVLLHAAPQF 4572
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
I + +N G A E+ + + W KDG I+ S + LK+
Sbjct: 4573 IVKPKNTTAAIG--AIVELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT 4625
Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
D+GEY+C VG+S +A + V+ N L P+ N E
Sbjct: 4626 LNSTSDSGEYTCMAQNSVGSSTVSAFINVD----NNILPTPKPSSNQKNVAVITCYERNQ 4681
Query: 1223 E-TLDVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKL 1279
+ +TW Y + ++ +++ L E D YTC + + + +
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPH 4741
Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
E P++ ++ + G V L D + P +V +K +K
Sbjct: 4742 LTSAFEGVPEVKTIDK-VEVNNGDSVVL--DCEVTSDPLTTHVVWTKNDQKMLDDDAIYV 4798
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
+ SL + VE D G+YK N+ G A + + + + P + + S INI
Sbjct: 4799 LPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP----LTGFEGSGINI 4854
Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D+ N G S+ + E +T I+ + T T T
Sbjct: 4855 --DDSSNAGGSSRREAYKKENEDASTTTITTTSPTTTTT 4891
Score = 39.9 bits (89), Expect = 0.019
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
+ KP KN T +EL C G P P +TW +DGK ++ +K
Sbjct: 4573 IVKP-KNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIA-YSHLKVTLNSTS 4630
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGI 1567
Y C+A N G S + +
Sbjct: 4631 DSGEYTCMAQNSVGSSTVSAFINV 4654
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 11/91 (12%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E + P ++ R +G+T CQV G P P +TW R K + F
Sbjct: 3209 TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNG---KEIEQFN---- 3261
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
L IR D G ++C+A N AG A
Sbjct: 3262 ----PVLHIRNATRADEGKYSCIASNEAGTA 3288
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P ++ +C +G P PQ+ W TA+ + + D + I V D G
Sbjct: 3965 PAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ---INNVSLSDKGV 4021
Query: 581 FTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613
+TC A+N AG + + +V+AP+ +G V
Sbjct: 4022 YTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV 4055
Score = 37.9 bits (84), Expect = 0.078
Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 26/201 (12%)
Query: 408 FEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKG 467
FE V R GDT+ + AE+ ++ V + D S Q+ K+ EK
Sbjct: 2763 FEKEREEVVARVGDTMLLTCN--AESSVPLSSVYW---HAHDESVQNGVITSKYAANEKT 2817
Query: 468 WVPAQYLMDENNY---TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPD 523
+D+ + T + + +K KL V E P ++Q + PI +
Sbjct: 2818 LNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIIL---------- 2867
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + +C G P P I + + + S + + +TLVI E G +TC
Sbjct: 2868 GKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIG-----STLVIDNPQKEVEGRYTC 2922
Query: 584 VAKNAAGFASSTTELIVEAPL 604
+A+N AG S +++VE L
Sbjct: 2923 IAENKAG--RSEKDMMVEVLL 2941
Score = 37.5 bits (83), Expect = 0.10
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDM 688
EG+P K V+ G ++L+C + + P + W ++++ D+ I V +
Sbjct: 4747 EGVPEV--KTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPNNS- 4803
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
L + NV+K+ EG Y VA N G+A L + G+ P
Sbjct: 4804 ------LVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP 4843
Score = 35.9 bits (79), Expect = 0.32
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E +P + +R P G C +I W R A + + +
Sbjct: 512 TRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTER--- 568
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
+ TL I V DAG + C+A+NA G ++ L I+E P
Sbjct: 569 NPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPP 611
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P + W K+G KL D ++ I S +++ S S +YT A N+ G+S+V
Sbjct: 4595 GPPHPTITWAKDG-KLIEDSKFEIA----YSHLKVTLNSTSDSGEYTCMAQNSVGSSTVS 4649
Query: 1658 VTLKV 1662
+ V
Sbjct: 4650 AFINV 4654
Score = 33.9 bits (74), Expect = 1.3
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 523 DGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C EG P P W F Q + K + ++ ++++ T+V+ V G +
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLPKEA----VFVNNNH--TVVVNNVTKYHTGVY 1982
Query: 582 TCVAKNAAGFASSTTELIVEA-PLSDHG---SEMTVXXXXXXXXXXXXADIL-EGIPPTF 636
C A N G A T + V P + G SE+TV D + GI T
Sbjct: 1983 KCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 637 SKKP 640
+ KP
Sbjct: 2043 NGKP 2046
Score = 33.9 bits (74), Expect = 1.3
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+ +++ C+V G P P +TW + + + Q+ + +V E+ G++
Sbjct: 2112 ENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQF-KIVHAEI--AHKGSYI 2168
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
C+AKN G A + ++ I+ P+ G
Sbjct: 2169 CMAKNDVGTAEISFDVDIITRPMIQKG 2195
Score = 33.9 bits (74), Expect = 1.3
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G +V +C+V P + W + K D +Y +N +LV+ V D G +
Sbjct: 4762 NGDSVVLDCEVTSDPLTTHVVWTKNDQ--KMLDDDAIYVLPNN--SLVLLNVEKYDEGVY 4817
Query: 582 TCVAKNAAGFASSTTELIV 600
CVA N+ G A T+L V
Sbjct: 4818 KCVASNSIGKAFDDTQLNV 4836
Score = 32.7 bits (71), Expect = 3.0
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 510 PIFVEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P+FVE + + + + +CQV G P+P + W + S F D++++
Sbjct: 1736 PVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLF-----DESLSL 1790
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593
L I ++ + A +C A+N AG AS
Sbjct: 1791 LRIEKLTGKSA-QISCTAENKAGTAS 1815
Score = 31.5 bits (68), Expect = 6.8
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
TP GS C V GYP P I+W IK ++ D TL I E E
Sbjct: 4147 TPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD---GTLHI-EKAEERHL 4202
Query: 580 TFTCVAKNAAG 590
+ C AKN AG
Sbjct: 4203 IYECTAKNDAG 4213
>Z47068-8|CAA87335.1| 5175|Caenorhabditis elegans Hypothetical protein
F15G9.4a protein.
Length = 5175
Score = 213 bits (520), Expect = 1e-54
Identities = 282/1187 (23%), Positives = 464/1187 (39%), Gaps = 142/1187 (11%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + EC +E ITW RQ K Q + + L I + PEDA +++C
Sbjct: 2957 GDPLTLECPIEDTSGVHITWSRQFG--KDGQLDMRAQSSSDKSKLYIMQATPEDADSYSC 3014
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+A N AG A + ++ V P G + EGIPP
Sbjct: 3015 IAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCR-TEGIPP--------- 3064
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
PE I+W G+ I+ ++ + D+ L+I N+K
Sbjct: 3065 -----------------PE--ISWFLDGKPILEMPGVTYK-QGDLS-----LRIDNIKPN 3099
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
QEG YT VA N+ G A ++I EPP+V+ + M V +G + +V GNP
Sbjct: 3100 QEGRYTCVAENKAGRAEQDTYVEI----SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPE 3155
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
P + W K+ +P + S L+ + D G YT A N G ++T+ + V
Sbjct: 3156 PVVNWLKDGEPYTS-DLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV- 3213
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
PP + + + KE T + +VT PVP +TW RN + I + F
Sbjct: 3214 ------LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-------EQF 3260
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
N L I N + D G Y C+ASN AG + A IDV K TF H + ++ E
Sbjct: 3261 ---NPVLHIRNA-TRADEGKYSCIASNEAGTAV--ADFLIDVFTKPTFETH-ETTFNIVE 3313
Query: 943 GKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
G++ +EC+ H T W + + MD+ II R D G+ C+
Sbjct: 3314 GESAKIECKIDGHPKPTISWLKGGRPFN-MDN--IILSPRGDTLMILKAQRFDGGLYTCV 3370
Query: 1001 V------KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE 1054
+Q+ + K I E I + V ++ + + + T V W+R G+
Sbjct: 3371 ATNSYGDSEQDFKVNVYTKPYIDETIDQTPK-AVAGGEIILKCPVLGNPTPTVTWKR-GD 3428
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEIIT 1111
P +++ ++ I + + D G+YSCI +E+ T V P +
Sbjct: 3429 DAVPNDSRHTIVNNYDLK---INSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR 3485
Query: 1112 RLQN-QKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
+ N +V + + T + +T + WF+ + + ++ DG + I
Sbjct: 3486 KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDG--SHITINKAK 3543
Query: 1170 LDDAGEYSC----EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223
L D G+Y C E G S IL + P I+ + + + + A T YL I
Sbjct: 3544 LSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVART-IYLECPISGIP 3602
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
DV W K I T+ +++ T I DQ YTC + K++ +
Sbjct: 3603 QPDVIWTKNGMDINMTDSRVILAQ-NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 3661
Query: 1282 EVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDE-----WIVNSKIIKKCKHTK 1335
+V+ PP+ + + IKR G +TL + D+ W +S+ +
Sbjct: 3662 DVLS-PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDN 3720
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I LTI + +AG+Y N G A +E V IL SPP +++I +
Sbjct: 3721 VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL---SPP----VIDISRN 3773
Query: 1396 SINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-SVKNITKTQT--------SIQNLKT 1445
+ +P+ N TI+ V + +W+ + K +T + +Q L+T
Sbjct: 3774 DV-----QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRT 3828
Query: 1446 NSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+S + ++ A N+ + + + + + S + P+K + E I L C
Sbjct: 3829 DSDHAGKWSCVAENDAGVKELEMVLDVF----TPPVVSVKSDNPIKAL----GETITLFC 3880
Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
G P P++ W + G + A+ + + Y C A N G
Sbjct: 3881 NASGNPYPQLKWAKGGSLIFDSPDGARISLKG-ARLDIPHLKKTDVGDYTCQALNAAGTS 3939
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
E S V + P I D+ + + + +G P P++ W NG L +
Sbjct: 3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTP- 3998
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
IT ++ I+I + S YT A N AG+ ++ + V P
Sbjct: 3999 GITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 4045
Score = 194 bits (473), Expect = 6e-49
Identities = 268/1073 (24%), Positives = 421/1073 (39%), Gaps = 82/1073 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
PTF + EG +EC++ P+P I+WL KG +NI ++ D
Sbjct: 3300 PTFETHETTFNIVEGESAKIECKIDGHPKPTISWL-KGGRPFNMDNIILSPRGD------ 3352
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I ++F G YT VA N G++ + + T + + K++ G +I
Sbjct: 3353 TLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGEII 3409
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
L V+GNP PT+TW + + A+P S H TI+ +K V T A I
Sbjct: 3410 LKCPVLGNPTPTVTWKRGD---DAVPNDS---RH--TIVNNYDLKINSVTTEDAGQYSCI 3461
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A A E P F+ + + V E TI + VT P+PSI+W+R ++
Sbjct: 3462 AVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKP 3521
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ + + + DG +I + N D G Y C ASN AG S + I V
Sbjct: 3522 VYLYDRYSISPDGSHITI---NKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKS 3578
Query: 933 HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
++ + +T+ LEC S W N +I+ D R I+ +
Sbjct: 3579 NIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNN-ETFGIENVQ 3637
Query: 991 XXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEV------EI 1040
D G C + + + + + PEF I Q +E D L +I
Sbjct: 3638 VTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDI 3697
Query: 1041 NSETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ DV W +D + + D G RKL I S+ + G Y+CI + + A
Sbjct: 3698 ADQVMDVSWTKDSRALDGDLTDNVDISDDG--RKLTISQASLENAGLYTCIALNRAGEAS 3755
Query: 1100 VTV-VEL--PPEI-ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQ 1153
+ VE+ PP I I+R Q N+ T G ++W K+G E+ +I+
Sbjct: 3756 LEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR 3815
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
+ G Q L+I D D AG++SC + G + +L V P + +++ I
Sbjct: 3816 IVEQG--QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKAL 3872
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
T + + W K S+I D+ IS +K L I + D +YTC
Sbjct: 3873 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQ 3931
Query: 1270 LLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
L+A T++ V V V PP+I + R+ +TL Q P P W +N
Sbjct: 3932 ALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGT 3991
Query: 1327 IIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--S 1382
+ H+ P I S S + I V +D G+Y EN G ++ NV ++ P S
Sbjct: 3992 AL---THSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS 4048
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQ 1441
G ++E + + I C E + ++ ++T V+ +T +I
Sbjct: 4049 NGGTKQVIEGELAVIE-CLVEGYPAPQ---VSWLRNGNRVETGVQ-GVRYVTDGRMLTII 4103
Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
++ S + A NE + + T E V+ KI + T +T L
Sbjct: 4104 EARSLDSGIYLCSATNEAGSAQQAYTLE---VLVSPKIITSTPGV----LTPSSGSKFSL 4156
Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G P P ++W +G +K + + Y+C A ND G
Sbjct: 4157 PCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADT 4216
Query: 1561 TSCVVGIQQKPVITIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
V P I+ S N I G E ++ IE E W KNG L
Sbjct: 4217 LEFPVQTIVAPKISTSGNRYINGSE--GTETVIKCEIES-ESSEFSWSKNGVPLLPSN-- 4271
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
N+ E +I+I + S +Y+ A+N AG ++ + L V P E P
Sbjct: 4272 NLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP 4324
Score = 187 bits (456), Expect = 7e-47
Identities = 248/1061 (23%), Positives = 417/1061 (39%), Gaps = 91/1061 (8%)
Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
G DI L C L + W G E D +V I SD H L IT+ K
Sbjct: 1657 GKDISLSCDLQTESDDKTTFVWSINGSE--SDRPDNVQIPSDGHR----LYITDAKPENN 1710
Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSAQVVGNPR 763
G Y N G+A + L + EPP +EP+ + + +IL QV GNP+
Sbjct: 1711 GKYMCRVTNSAGKAERTLTLDVL----EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPK 1766
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEGIAETSAVITV 822
PT+ W + V KS S+++L+ +K+ + + AEN G A I
Sbjct: 1767 PTVIWKIDGNDVD----KSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFI-- 1820
Query: 823 EEPTEENAEPPLFINRFQEITV-KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
+N P F N + T+ +E TI L V+ ITW + ++ ++ I
Sbjct: 1821 -----QNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWMKQGLPLTENDAI-- 1872
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
F +N L I N + + + Y CVA+N+AG+ S V + V + +K+ + E
Sbjct: 1873 -FTLDNTRLTILNANRDHED-IYTCVANNTAGQVSKDFDVVVQV--LPKIKNAVVTLEIN 1928
Query: 942 EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
EG+ +IL C + T + KW N+ ++ +E + GV KC
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLP----KEAVFVNNNHTVVVNNVTKYHTGVYKC 1984
Query: 1000 IVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWERDG 1053
+ Q T+ V T P F L + E+ + +E + + A + W +G
Sbjct: 1985 YATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNG 2044
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
+ + + G R L+I + D G Y+C + +E+ A T V++PP I+
Sbjct: 2045 KPFLAETDGVQTLAGG--RFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
V + N E+T K + +V W KDG + +Q+ +G Q+ KI +
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEG--QQFKIVHAE 2160
Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIP---DET 1224
+ G Y C N TA ++ + I + + + I +V A L + P D+
Sbjct: 2161 IAHKGSYICMAKNDVGTAEISFDVDIITRPM-IQKGIKNIVTAIKGGALPFKCPIDDDKN 2219
Query: 1225 L--DVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLK 1280
+ W + I+ + E + R L I TE+D+ +Y+C V DA +
Sbjct: 2220 FKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDF 2279
Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KKCKHTKP 1336
V PP I+ D ++ S VTL P+P+ W + + I + P
Sbjct: 2280 KATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIP 2339
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVTILDKPSPPGKPNILEIDS 1394
+ + L I +++ DAG Y +N+ G DV +NV + K G P+ E
Sbjct: 2340 NGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ 2399
Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
+ + P I ++ + + + +++ + + + L+ S ++
Sbjct: 2400 NE-RVVISCPVYARPPAKITWLKAGKPLQSDKFVKT-SANGQKLYLFKLRETDSSKYTCI 2457
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPK 1512
A NE A +KV + + +P+ ++P ++ IT L C G P P
Sbjct: 2458 ATNE-----AGTDKRDFKV---SMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT 2509
Query: 1513 VTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+TW +DG ++ ++ Y CIA N G + + +
Sbjct: 2510 ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIP 2569
Query: 1571 PVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK---EYNITTKEK 1626
PVI E + E + G+ +V W K+G + D + I
Sbjct: 2570 PVIDGERREAVAVIEGFSSELFCDSNSTGV---DVEWQKDGLTINQDTLRGDSFIQIPSS 2626
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+ ++S S +YT N AG + V D PS
Sbjct: 2627 GKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS 2667
Score = 187 bits (456), Expect = 7e-47
Identities = 229/1061 (21%), Positives = 423/1061 (39%), Gaps = 83/1061 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F + K + G + L+C P P I ++ G+ + + + + S
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--------GS 2905
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I N +K EG YT +A N+ G + +++++ PP++ + ++ V+ G+ +
Sbjct: 2906 TLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLL----PPKLSKEWINVEVQAGDPLT 2961
Query: 754 LSAQVVGNPRPTITWCKN-NKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
L + ITW + K + + +S D + I++ +D Y+ A N
Sbjct: 2962 LECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATP-EDADSYSCIAVNDA 3020
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G AE +TV P P +F + F + T+++ R P P I+W+ + +
Sbjct: 3021 GGAEAVFQVTVNTP------PKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGK 3074
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTF 930
I +T + ++ L I N+ G Y CVA N AG++ V I + +V
Sbjct: 3075 PILEMPGVT--YKQGDLSLRIDNIKPN-QEGRYTCVAENKAGRAEQDTYVEISEPPRVVM 3131
Query: 931 VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
+ + EG+ + C+ + W + + + +++Q +
Sbjct: 3132 ASEVMR---VVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTS----DLLQFSTKLSYLHLR 3184
Query: 988 XXXXXDVGVIKCIV--KDQETSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSET 1044
D G CI K E+ T V+ +P I + + + KE + ++ ++
Sbjct: 3185 ETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 1045 AD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102
V W+R+G+ + E+ + L+IRN + DEG+YSCI +E+ TA
Sbjct: 3245 VPYVTWKRNGK---------EIEQFNPV--LHIRNATRADEGKYSCIASNEAGTAVADFL 3293
Query: 1103 --VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
V P T + +G A E ++ + W K G N + + +
Sbjct: 3294 IDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMDN---IILSPR 3350
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTL-RLPEFILVPANTD 1213
L I D G Y+C NS + + +P I+ T+ + P+ + A +
Sbjct: 3351 GDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGE 3407
Query: 1214 AYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
L + + T VTW + + + + T++++ L I T +D +Y+C+ ++
Sbjct: 3408 IILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNY---DLKINSVTTEDAGQYSCIAVN 3464
Query: 1273 --AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
TT EV+ P + Y + +T+ + P P+ W K +
Sbjct: 3465 EAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPV-- 3522
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
+ + SI + +TI K + +D G Y R N G +D+++ + IL P K NI+
Sbjct: 3523 YLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDIDLILKIL-VPPKIDKSNII 3581
Query: 1391 EIDSSSI--NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
+ + I + P + + + +I+ T+ + I+N++
Sbjct: 3582 GNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIK-ETKIQSPTVEKPLKNIT-TEPNEDIE-LTCIF 1505
R+ A N + + + + + PT+++ IT T P + E +
Sbjct: 3642 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
V K + DG + + R Y CIA N GE V
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGR-KLTISQASLENAGLYTCIALNRAGEASLEFKV 3760
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I PVI IS D++ + V ++ + G P P + W KNG ++ +D+ NI E
Sbjct: 3761 EILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE--NIRIVE 3818
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ V++I H+ K++ A N AG +E+ L V+ P
Sbjct: 3819 QGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859
Score = 181 bits (440), Expect = 6e-45
Identities = 248/1089 (22%), Positives = 419/1089 (38%), Gaps = 83/1089 (7%)
Query: 632 IPPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
+PPT K K + E S + L C PEPDI W FK E + ENI+ I +
Sbjct: 2285 VPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITW-FKDGEAIHIENIADIIPNG-E 2342
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748
+ + LKIT +K+ G YT A N G + + + T K E + +S +Q
Sbjct: 2343 LNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYES---QQ 2399
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKA 807
E V++S V P ITW K KP+++ K+ + + + K ++ D YT A
Sbjct: 2400 NERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSANGQKLYLFKLRET-DSSKYTCIA 2458
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G + +++ + + P + R ITV L +P P+ITW
Sbjct: 2459 TNEAGTDKRDFKVSML--VAPSFDEPNIVRR---ITVNSGNPSTLHCPAKGSPSPTITWL 2513
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ I P++ FD +L I+ + D G Y C+A+NS G + + +
Sbjct: 2514 KDGNAIEPNDRYVF-FDAGR-QLQISKTEGS-DQGRYTCIATNSVGSDDLENTLEVIIPP 2570
Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYH-----NKKEISGMDHREIIQEGRX 981
V + +++ EG + L C ++ T V +W N+ + G +I G+
Sbjct: 2571 VIDGER-REAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKK 2629
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEV 1038
D G CIV++ + + P +L + + V V
Sbjct: 2630 MSFLSARKS--DSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANI-QTIVPYYPV 2686
Query: 1039 EIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
EIN S V W D + ++P Y+ G K+ + V G Y+C ++
Sbjct: 2687 EINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV--RSQVEHAGTYTCEAQN 2744
Query: 1094 ESCTAE---VTVVELPPEIITRLQNQKVNKGNKA--TFEIELTKGDALVRWFKDGSEIQF 1148
A + V PP + G+ T E + + V W +Q
Sbjct: 2745 NVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQ- 2803
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLP 1203
+ I ++ L + + LDD G Y C N K ++ +E P +L
Sbjct: 2804 NGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLY 2863
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
IL T P T + + K + ++++ +I TL+I ++ +
Sbjct: 2864 PIILGKRLTLDCSATGTPPPT--ILFMKDGKRLNESDEVDIIGS----TLVIDNPQKEVE 2917
Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
YTC+ + +S + VEV+ PPK+ ++ G +TL + + W
Sbjct: 2918 GRYTCIAENKAGRSEKDMMVEVL-LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW 2976
Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
+ S KS L I + DA Y N+ G A+ VT+ P
Sbjct: 2977 SRQFGKDGQLDMRAQSSSDKS-KLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Query: 1382 SPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
G + EI + + E I +++ + + I ++ K I
Sbjct: 3036 KIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFL-DGKPILEMPGVTYKQ-GDLSLRI 3093
Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
N+K N R+ A N+ + +E Y ++ + P V + +
Sbjct: 3094 DNIKPNQEGRYTCVAENK---AGRAEQDTYVEIS-----EPPRVVMASEVMRVVEGRQTT 3145
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-XYKCIAFNDHGEV 1559
+ C G P+P V W +DG+ + + + Y CIA N GE
Sbjct: 3146 IRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGES 3205
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+T+ V + P I +E+ + K G+ ++V + G P P V W +NG ++E ++
Sbjct: 3206 QTTTDVEVLVPP--RIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIE---QF 3260
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
N V+ I+ R+ KY+ ASN AGT+ + + V+ KP+ +
Sbjct: 3261 N-------PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE 3313
Query: 1680 RESVTIEWK 1688
ES IE K
Sbjct: 3314 GESAKIECK 3322
Score = 180 bits (437), Expect = 1e-44
Identities = 229/1065 (21%), Positives = 423/1065 (39%), Gaps = 85/1065 (7%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP + V EG + C + PEP + WL GE D ++ +
Sbjct: 3126 PPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSD-----LLQFSTKL-- 3178
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S L + GTYT +A N+ GE+ +++ PP++ + + + ++G +
Sbjct: 3179 SYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLV----PPRIEDEERVLQGKEGNTY 3234
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ QV G P P +TW +N K ++ + + ++ DEG Y+ A N G
Sbjct: 3235 MVHCQVTGRPVPYVTWKRNGKEIEQF--------NPVLHIRNATRADEGKYSCIASNEAG 3286
Query: 813 IAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
A +I V +PT E E + E + K+ ++ +P P+I+W +
Sbjct: 3287 TAVADFLIDVFTKPTFETHE--------TTFNIVEGESAKIECKIDGHPKPTISWLKGGR 3338
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
+ + I + G+ + ++ D G Y CVA+NS G S +V + K
Sbjct: 3339 PFN-MDNIILSPRGDTLMILKA---QRFDGGLYTCVATNSYGDSEQDFKVNV-YTKPYID 3393
Query: 932 KHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
+ + ++ + G +IL+C + T + W + I+
Sbjct: 3394 ETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNN---YDLKINSV 3450
Query: 990 XXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEINSE-T 1044
D G CI V + T E I P F+RK + +EV E D ++ + S
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
+ W R G+ ++Y G + I + D G+Y C +E+ T+++ +
Sbjct: 3511 PSISWFR-GDKPVYLYDRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLIL 3567
Query: 1103 -VELPPEI--ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDG 1158
+ +PP+I + N E ++ V W K+G +I ++ ++ +
Sbjct: 3568 KILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS-RVILAQ 3626
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA-------ILTVEEPSINFTLRL--PEFILVP 1209
+ I + + D G Y+C N A +L+ E I+ T E +
Sbjct: 3627 NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTIT 3686
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
L +I D+ +DV+W K ++ D ISD R L I + + ++ YTC
Sbjct: 3687 LTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISD-DGRKLTISQASLENAGLYTC 3745
Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
+ L+ L+ +V P ++D R + ++ + P P+ +W+ N
Sbjct: 3746 IALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNG 3805
Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
K + ++ + I + L I + ++ AG + EN+ G ++EM + + P
Sbjct: 3806 KEVTDDENIR--IVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSV 3863
Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
K N ++ +I + + N + + D+ + + ++ + I +LK
Sbjct: 3864 KSDNPIKALGETITLFCNASGNP-YPQLKWAKGGSLIFDSPDGARI-SLKGARLDIPHLK 3921
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
+ A+N S+AS + + V+ +I ++ + + + L C+
Sbjct: 3922 KTDVGDYTCQALNAAGTSEASVSVD---VLVPPEINRDGIDMSPR---LPAQQSLTLQCL 3975
Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P++ W +G L T T + Y C A N G
Sbjct: 3976 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 4035
Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
V + Q PV ISN KQ + G+ ++ ++EG P P+V W +NGN++E + +
Sbjct: 4036 MYNVDVVQAPV--ISNGGTKQVIE-GELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GV 4091
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ I E + S Y A+N AG++ TL+V P
Sbjct: 4092 RYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 4136
Score = 177 bits (431), Expect = 7e-44
Identities = 270/1198 (22%), Positives = 453/1198 (37%), Gaps = 124/1198 (10%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V +C G P P+I W + ++ + + Y L+I + ED G FTC+A+
Sbjct: 810 VTLQCLAVGIPPPEIEWQKGNVLLATLNNPR--YTQLADGNLLITDAQIEDQGQFTCIAR 867
Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
N G S +T L+V +S +L +PP + +
Sbjct: 868 NTYGQQSQSTTLMVTGLVS---------------------PVLGHVPP-------EEQLI 899
Query: 647 EGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG D+ L C +V P+P I W+ K ++ V +E ++ IE S+L++ E
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWI-KDDKPV-EEGPTIKIEGG----GSLLRLRGGNPKDE 953
Query: 706 GTYTVVAVNREGEASLPI-VLKIKTGE----KEPPQVIEPLKSMI-------------VR 747
G YT +AV+ G ++L I V IK E E V +P S + V
Sbjct: 954 GKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVL 1013
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKD-EGVYTL 805
GE + V G P P ITW + +P+ P D T T++ K K GVYT
Sbjct: 1014 DGEGFAIPCVVSGTPPPIITWYLDGRPI--TPNSRDFTVTADNTLIVRKADKSYSGVYTC 1071
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
+A NS G E I + P+ + + V +P P IT
Sbjct: 1072 QATNSAGDNEQKTTIRI-------MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVIT 1124
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
W + + T+ E+ L I NV +E G + C A N+AG + +T+
Sbjct: 1125 W------LLDDKPFTEGVVNEDGSLTIPNV-NEAHRGTFTCHAQNAAGNDTRTVTLTVHT 1177
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS---HTVSTKWYHNKKEISGMDHREIIQEGRXX 982
++ +K + ++LEC V Y +K S + I ++G
Sbjct: 1178 TPTINAENQEKI--ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG--- 1232
Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
+ GV C V + L T+ E + + + V +EI
Sbjct: 1233 ALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPC 1292
Query: 1043 ETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
V W ++G +K + K+ + G +R I +D G Y+C++ +E+ T
Sbjct: 1293 RATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR---IYEADKNDIGNYNCVVTNEAGT 1349
Query: 1098 AEVTV---VELPPEIITRLQ-NQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152
+++T V+ PP I+ Q N G++ + + A V WF+ G I
Sbjct: 1350 SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG--IAIGTDT 1407
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA---ILTVEEPSINFTLRLPEFIL 1207
+ + L I ++DA Y+C+ N K A + + P I + + +
Sbjct: 1408 KGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESI 1467
Query: 1208 VPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
++ + + ++WY K +I+D + D KR L + K D Y
Sbjct: 1468 KESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD--KRKLHVFKAKITDSGVY 1525
Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV +A +V P +D Y+++ K G +VTL FP P W+V
Sbjct: 1526 KCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVV 1585
Query: 1324 NSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
+ +++ K K ++ + +L V G Y ++ D+++ +++L P
Sbjct: 1586 DGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPI 1645
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
N+ I++ D + + T + + E D + + + + + I +
Sbjct: 1646 VGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPS-DGHRLYITD 1704
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
K ++ ++ N + +E T V++ P E K I P I L
Sbjct: 1705 AKPENNGKYMCRVTNS---AGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNP---IILQ 1758
Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
C G P+P V W DG + + ++ C A N G
Sbjct: 1759 CQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRD 1817
Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNI 1621
IQ T NE ++ E + + ++ W K G L END I
Sbjct: 1818 FF--IQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA---I 1872
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
T + T + I R H YT A+NTAG S + + V P K + V+ EI+
Sbjct: 1873 FTLDNTR-LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP-KIKNAVVTLEIN 1928
Score = 157 bits (380), Expect = 1e-37
Identities = 244/1092 (22%), Positives = 419/1092 (38%), Gaps = 106/1092 (9%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GES 751
+ + +K G YT + N GEA + +PP + + L S ++
Sbjct: 2630 MSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN----DPPSISDELSSANIQTIVPYYP 2685
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
V ++ V G+P P + W ++KP++ A ++G+T I +V+ G YT +A
Sbjct: 2686 VEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV---RSQVEHAGTYTCEA 2742
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITW 866
+N+ G A ++ V PP F +E+ + T+ L + P+ S+ W
Sbjct: 2743 QNNVGKARKDFLVRV-------TAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYW 2795
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ ++E + + IT + L +TN+ + D G Y C A N AG + ++ + +E
Sbjct: 2796 HAHDESVQ-NGVITSKYAANEKTLNVTNIQLD-DEGFYYCTAVNEAGITKKFFKLIV-IE 2852
Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXX 984
F+ QK Y GK + L+C + T + + + K ++ D +II
Sbjct: 2853 TPYFLDQ-QKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII----GSTL 2907
Query: 985 XXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
G CI +++ M+V P+ ++ + EV+ D LE I
Sbjct: 2908 VIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIE 2967
Query: 1042 SETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + W R + K + + KLYI + D YSCI +++ AE
Sbjct: 2968 DTSGVHITWSR--QFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEA 3025
Query: 1101 T---VVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSEIQFSNHIQL 1154
V PP+I + + T EI T+G + WF DG I +
Sbjct: 3026 VFQVTVNTPPKIFGDSFSTTEIVAD-TTLEIPCRTEGIPPPEISWFLDGKPILEMPGV-- 3082
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
T L+I + + G Y+C + G ++ + + EP + E + V
Sbjct: 3083 TYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR--VVMASEVMRVVE 3140
Query: 1211 NTDAYLTVEI---PDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
+ E+ P+ V W K + D +F+ K L +R+ T D Y
Sbjct: 3141 GRQTTIRCEVFGNPEPV--VNWLKDGEPYTSDLLQFS----TKLSYLHLRETTLADGGTY 3194
Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
TC+ + +S T VEV+ PP+I D ER + K G+ + P P W N
Sbjct: 3195 TCIATNKAGESQTTTDVEVL-VPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN 3253
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K I+ + L I+ D G Y N G A + + + KP+
Sbjct: 3254 GK----------EIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPT-- 3301
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI------SVKNITKTQT 1438
E ++ NI G S I ++ T W+ ++ NI +
Sbjct: 3302 -----FETHETTFNIV------EGESAKIECKIDGHPKPTISWLKGGRPFNMDNIILSPR 3350
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNE 1497
L + RF V + ++ + +KV TK T+++ K +
Sbjct: 3351 G-DTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVA---GG 3406
Query: 1498 DIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+I L C G P P VTW R D ++ T N Y CIA N+
Sbjct: 3407 EIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEA 3466
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G + T + KP ++ + + D + + P P + W++ +
Sbjct: 3467 GNLTTHYAAEVIGKPTFVRKGGNLYEVIE-NDTITMDCGVTSRPLPSISWFRGDKPVYLY 3525
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
Y+I+ S I I + K S KY ASN AGTS +++ LK+ P + +I
Sbjct: 3526 DRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGN 3583
Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
++ + TI + P+ G+ K+ D N + ++ ET+ I+ + +
Sbjct: 3584 PLAIVARTIYLECPI--SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1737 YMFRVIAQNPVG 1748
+ A N G
Sbjct: 3642 GRYTCTATNRGG 3653
Score = 155 bits (377), Expect = 2e-37
Identities = 223/1013 (22%), Positives = 380/1013 (37%), Gaps = 81/1013 (7%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L I + K G+Y N G A+ L ++ PP ++ V + S++L
Sbjct: 2063 LHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQV----PPTIVNEGGEYTVIENNSLVL 2118
Query: 755 SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+V G P P +TW K+ +PV K++ S+G I ++ +G Y A+N
Sbjct: 2119 PCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIV---HAEIAHKGSYICMAKNDV 2175
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG---TIKLVARVTRNPVPSITWYR 868
G AE S + + P+ + I KG K +N I W R
Sbjct: 2176 GTAEISFDVDI-------ITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLR 2228
Query: 869 NNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
N + I +E + L I NV +E D G Y C N AG++S + T+ V
Sbjct: 2229 NYQPIDLEAEDARITRLSNDRRLTILNV-TENDEGQYSCRVKNDAGENSFDFKATVLVPP 2287
Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG--RXXX 983
+ K+ E TV L C + W+ + + I + +II G
Sbjct: 2288 TIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ 2347
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRK--LQDFEVKEKDVAILEV 1038
D G C + S V TIP+ + D+E ++ + ++
Sbjct: 2348 LKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC 2407
Query: 1039 EINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
+ + A + W + G KP ++ + + +KLY+ D +Y+CI +E+ T
Sbjct: 2408 PVYARPPAKITWLKAG---KPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGT 2464
Query: 1098 ----AEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147
+V+++ P P I+ R+ VN GN +T KG + W KDG+ I+
Sbjct: 2465 DKRDFKVSMLVAPSFDEPNIVRRI---TVNSGNPSTLHCP-AKGSPSPTITWLKDGNAIE 2520
Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP 1203
N + D +Q L+I + D G Y+C VG+ L V P + R
Sbjct: 2521 -PNDRYVFFDAGRQ-LQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGER-R 2577
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDT---EKFTLISDVKKRTLIIRKCT 1259
E + V + L + +DV W K I +DT + F I K+ +
Sbjct: 2578 EAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFL-SAR 2636
Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFP 1315
+ D YTC++ + A KL V PP I D I+ V + P
Sbjct: 2637 KSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSP 2696
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
P W+ + K ++ + + +L I + + AG Y +NN G A + V
Sbjct: 2697 HPKVYWLFDDKPLEP-DSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLV 2755
Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
+ P + + + + + C E++ + +Y+ + + S
Sbjct: 2756 RVTAPPHFEKEREEVVARVGDTMLLTC--NAESSVPLSSVYWHAHDESVQNGVITSKYAA 2813
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
+ ++ N++ + + AVNE I T +++K+I I++P K
Sbjct: 2814 NEKTLNVTNIQLDDEGFYYCTAVNEAGI-----TKKFFKLI---VIETPYFLDQQKLYPI 2865
Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
+ + L C G P P + + +DGK+L + Y CIA
Sbjct: 2866 ILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAE 2925
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
N G E +V + P +S E I + + GD + IE + W + K
Sbjct: 2926 NKAGRSEKDMMVEVLLPP--KLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGK- 2982
Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ + + S + I + + Y+ A N AG + + V P
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Score = 155 bits (375), Expect = 4e-37
Identities = 250/1241 (20%), Positives = 449/1241 (36%), Gaps = 107/1241 (8%)
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+ +N A F T L + DH T D++ + P
Sbjct: 1866 LTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTL 1925
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
++EG +I+L C P P W F ++ P E + V ++ H + + NV K+
Sbjct: 1926 EINEGEEIILTCDAEGNPTPTAKWDFNQGDL-PKEAVFV---NNNH----TVVVNNVTKY 1977
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y A N+ G+A I + ++T + + E + V S+ L V
Sbjct: 1978 HTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTE--SELTVNLTRSITLECDVDDAIG 2035
Query: 764 PTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
I+W N KP A + T + G I K D G Y N G+A +
Sbjct: 2036 VGISWTVNGKPFLAETDGVQTLAGGRFLHIV---SAKTDDHGSYACTVTNEAGVATKTFN 2092
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+ V+ PP +N E TV E ++ L VT P P +TW ++ + +++
Sbjct: 2093 LFVQ-------VPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSV 2145
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT---FVKHLQK 936
+G+ ++V + G Y C+A N G A ++ DV+ +T K ++
Sbjct: 2146 QVLSEGQQFKIVHAEI---AHKGSYICMAKNDVGT----AEISFDVDIITRPMIQKGIKN 2198
Query: 937 SYETEEGKTVILECQTSHTVSTK----WYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXX 991
+G + +C + K W N + I + I +
Sbjct: 2199 IVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTE 2258
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQD---FEVKEKDVAILEVEINSETA 1045
D G C VK+ K T+ P I +D V+ V +
Sbjct: 2259 NDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEP 2318
Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTSVHDEGEYSCILRDESCTAE---- 1099
D+ W +DGE I +N D G + +L I D G+Y+C + + + E
Sbjct: 2319 DITWFKDGEAIH-IENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVN 2377
Query: 1100 VTVVELPPEIITRLQNQKVNKGN-KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157
V V+ +P + + ++ N + + + A + W K G +Q ++ + +
Sbjct: 2378 VNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSAN 2437
Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCT-AILTVEEPSINFTLRLPEFILVPANT 1212
G QKL ++ D+ +Y+C E G K + + PS + + + N
Sbjct: 2438 G--QKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNP 2495
Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
+ +TW K + IE +++ R L I K DQ YTC+ +
Sbjct: 2496 STLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFD--AGRQLQISKTEGSDQGRYTCIATN 2553
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+ + L+ + P ++D ER + G L D + + EW + I +
Sbjct: 2554 SVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFCDSNS-TGVDVEWQKDGLTINQ 2612
Query: 1331 CKHTKPS---IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
S I S ++ +D+G Y + N G A + + D PS
Sbjct: 2613 DTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS----- 2667
Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN- 1446
+ + SS NI P I VV W+ + ++ L N
Sbjct: 2668 --ISDELSSANIQTIVPY---YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNG 2722
Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTC 1503
+ + V K K+ ++ P EK + + + + LTC
Sbjct: 2723 ETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTC 2782
Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
VP V W+ + ++ T + N Y C A N+ G
Sbjct: 2783 NAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGIT 2842
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+ + + + P ++ +G + G PPP +++ K+G +L E
Sbjct: 2843 KKFFKLIVIETPYFL--DQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEV 2900
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
+I S + I ++ +YT A N AG S ++ ++V P + + + +
Sbjct: 2901 DII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQA 2956
Query: 1680 RESVTIEWKPPLDDGGLELT---KYAIE-------KHEPDNNRWIKVADVDRDVETYCIQ 1729
+ +T+E P D G+ +T ++ + + D ++ + D ++Y
Sbjct: 2957 GDPLTLEC-PIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCI 3015
Query: 1730 KLNE--NCEYMFRVIAQNPVG-FSEALESEPIVIKTALDVP 1767
+N+ E +F+V P F ++ + IV T L++P
Sbjct: 3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIP 3056
Score = 154 bits (374), Expect = 6e-37
Identities = 197/794 (24%), Positives = 327/794 (41%), Gaps = 74/794 (9%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A++ G PT + P V+ + L+C V IP P+I W KG ++ N +
Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQ 843
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
+ L IT+ + +G +T +A N G+ S L + TG P P + +
Sbjct: 844 ----LADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMV-TGLVSPVLGHVPPEEQL 898
Query: 746 VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
+ +G+ + LS VV G P+P+I W K++KPV+ PT S+ L+ KDEG YT
Sbjct: 899 I-EGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYT 957
Query: 805 LKAENSEG----------IAETSAVITVE-----EPTEENAEPP--LFINRFQEITVKEK 847
A + G I + V E +PT + +N ++ E
Sbjct: 958 CIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEG 1017
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKC 906
I V V+ P P ITWY + I+P S T D L++ D SG Y C
Sbjct: 1018 FAIPCV--VSGTPPPIITWYLDGRPITPNSRDFTVTADN---TLIVRKADKSY-SGVYTC 1071
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHN 963
A+NSAG + + TI + + Q S+ + C V T +
Sbjct: 1072 QATNSAGDNEQ--KTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDD 1129
Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020
K G+ + ++G G C ++ +T T+ + T P
Sbjct: 1130 KPFTEGV----VNEDGSLTIPNVNEAHR---GTFTCHAQNAAGNDTRTVTLTVHTTPTIN 1182
Query: 1021 RKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ Q+ + D +LE + V +W +GE I + + + G L ++N
Sbjct: 1183 AENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG---ALVLQNV 1239
Query: 1080 SVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD 1134
+ + G + C + ++S + +TV E P+II+ + V KG T
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHE-KPKIISEVPGVVDVVKGFTIEIPCRATGVP 1298
Query: 1135 ALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAIL 1189
++R W K+G +++ + ++D L+IY+ D +D G Y+C E G S+ T +
Sbjct: 1299 EVIRTWNKNGIDLKMDEK-KFSVD-NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHV 1356
Query: 1190 TVEEPSINF-TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTLISD 1247
V+EP I + + +V + VE VTW+++ I DT+ + + SD
Sbjct: 1357 DVQEPPIILPSTQTNNTAVVGDRVELKCYVE-ASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSD 1304
TL+I+ + +D YTC + K+ L+V V+ P K D + IK
Sbjct: 1416 ---GTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
+L + P P W +N K + K + + D K L + K + TD+G+YK N
Sbjct: 1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDK-RKLHVFKAKITDSGVYKCVARN 1531
Query: 1365 NCGHADVEMNVTIL 1378
G V ++
Sbjct: 1532 AAGEGSKSFQVEVI 1545
Score = 153 bits (372), Expect = 1e-36
Identities = 255/1182 (21%), Positives = 445/1182 (37%), Gaps = 104/1182 (8%)
Query: 523 DGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C V G P+P I W + KP ++ + + L +R P+D G +
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWIKDD---KPVEEGPTIKIEGGGSLLRLRGGNPKDEGKY 956
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
TC+A + AG +ST + V+ E + + E +
Sbjct: 957 TCIAVSPAG--NSTLHINVQLIKKP---EFVYKPEGGIVFKPTISGMDEKHVAVVNS--- 1008
Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
V +G + C + P P I W G I P+ + +D + L +
Sbjct: 1009 THDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSR-DFTVTAD-----NTLIVRKAD 1062
Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
K G YT A N G+ ++I P + S + + + V G+
Sbjct: 1063 KSYSGVYTCQATNSAGDNEQKTTIRI----MNTPMISPGQSSFNMVVDDLFTIPCDVYGD 1118
Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
P+P ITW ++KP DG S+TI + G +T A+N+ G + +T
Sbjct: 1119 PKPVITWLLDDKPFTEGVVNEDG---SLTIPNVNEA-HRGTFTCHAQNAAGNDTRTVTLT 1174
Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
V NAE QE + I L P P W E I S+ I
Sbjct: 1175 VHTTPTINAEN-------QEKIALQNDDIVLECPAKALPPPVRLWTYEGEKID-SQLIPH 1226
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
E+ LV+ NV E ++G + C SN AG+ S +T+ EK + + +
Sbjct: 1227 TI-REDGALVLQNVKLE-NTGVFVCQVSNLAGEDSLSYTLTVH-EKPKIISEVPGVVDVV 1283
Query: 942 EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
+G T+ + C+ + V W N ++ MD ++ + D+G C
Sbjct: 1284 KGFTIEIPCRATGVPEVIRTWNKNGIDLK-MDEKKFSVD-NLGTLRIYEADKNDIGNYNC 1341
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-----SETADVVWERDGE 1054
+V ++ ++ + + E L + V VE+ S A V W R G
Sbjct: 1342 VVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGI 1401
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP---- 1106
I Y E G L I++ SV D Y+C + + AE VTV+ P
Sbjct: 1402 AIGTDTKGYVVESDG---TLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKD 1458
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+++T+ + + + + + + + W+ + + T D K+ KL +
Sbjct: 1459 PDVVTQ---ESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKR-KLHV 1514
Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF-ILVPANTDAYLTVEIPDE 1223
+ + D+G Y C N+ + + E + L ++ V A +T+ P
Sbjct: 1515 FKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS 1574
Query: 1224 TL---DVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
+ W +V+E +K+ TL +D TL + + Y CV +
Sbjct: 1575 GFPVPQINWVVDGTVVEPGKKYKGATLSND--GLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632
Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTK 1335
+ VE+ IV + + G D++L D Q W +N + + +
Sbjct: 1633 DIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQ 1692
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEI 1392
D +T K EN G Y R+ N+ G A+ + + +L+ P P + N I
Sbjct: 1693 IPSDGHRLYITDAKPENN--GKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLI 1750
Query: 1393 DSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
++ I + + + TGN + + ++ ++D + W+ ++++ + I+ L T S +
Sbjct: 1751 GNNPIIL---QCQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLR--IEKL-TGKSAQI 1803
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT-EPNEDIELTCIFGGVPQ 1510
A N+ + + +++ I +PT + T +E I L C +
Sbjct: 1804 SCTAENKA----GTASRDFF----IQNIAAPTFKNEGDQETIFRESETITLDCPV-SLGD 1854
Query: 1511 PKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
++TW + G L A + + Y C+A N G+V V +Q
Sbjct: 1855 FQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQV 1914
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
P I N + + G+E ++T EG P P W N L KE T V
Sbjct: 1915 LP--KIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDFNQGDL--PKEAVFVNNNHTVV 1970
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
+ + + H+ Y A+N G + + + V KP G
Sbjct: 1971 --VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESG 2010
Score = 145 bits (351), Expect = 3e-34
Identities = 245/1099 (22%), Positives = 431/1099 (39%), Gaps = 110/1099 (10%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+PP SK+ V G + LEC + I W + D + + +S
Sbjct: 2941 LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW---SRQFGKDGQLDMRAQSSSDK- 2996
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGE 750
S L I +Y+ +AVN G A + + T PP++ + + +
Sbjct: 2997 -SKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADT 3051
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTH-SITILKPKKVKDEGVYTLKA 807
++ + + G P P I+W + KP+ +P T GD I +KP + EG YT A
Sbjct: 3052 TLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQ---EGRYTCVA 3108
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
EN G AE + + +EPP + + + V E + V NP P + W
Sbjct: 3109 ENKAGRAEQDTYVEI-------SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWL 3161
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ E + S+ + + + L T + D G Y C+A+N AG+S + T DVE
Sbjct: 3162 KDGEPYT-SDLLQFSTKLSYLHLRETTL---ADGGTYTCIATNKAGES----QTTTDVEV 3213
Query: 928 VT--FVKHLQKSYETEEGKTVILECQ-TSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX 983
+ ++ ++ + +EG T ++ CQ T V W N KEI + I+
Sbjct: 3214 LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIRNA---- 3269
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
D G CI ++ + + L+ T P F F + E + A +E +I
Sbjct: 3270 ------TRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKI 3323
Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ + W + G + RG L I D G Y+C+ + +E
Sbjct: 3324 DGHPKPTISWLKGGRPFN--MDNIILSPRGDT--LMILKAQRFDGGLYTCVATNSYGDSE 3379
Query: 1100 ----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLT 1155
V V P T Q K G + + + +K G + N + T
Sbjct: 3380 QDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDA-VPNDSRHT 3438
Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210
I LKI +DAG+YSC E GN + A + +P+ F + V
Sbjct: 3439 IVNNYD-LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPT--FVRKGGNLYEVIE 3495
Query: 1211 NTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
N + + L ++W++ + +++++ D T I K D +Y C
Sbjct: 3496 NDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHIT--INKAKLSDGGKYICR 3553
Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY-----QAFPQPNDEWIV 1323
+ T+ + + + + PPKI ++ I + Y PQP+ W
Sbjct: 3554 ASNEAGTSDIDLILKILVPPKI---DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK 3610
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS- 1382
N I ++ + + + I+ V+ TD G Y N G A + ++ +L P
Sbjct: 3611 NGMDINMTD-SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEF 3669
Query: 1383 --PPGKPNIL-EIDSSSINICWDEPENTGNSTI-IYYVVEYQEID--TTEWISVKNITKT 1436
+P I E D+ ++ E+ + + + + + + +D T+ + + + +
Sbjct: 3670 DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRK 3729
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP- 1495
T Q N+ + A+N A E + +KV +I SP V +N +P
Sbjct: 3730 LTISQASLENAGL-YTCIALNR-----AGEASLEFKV----EILSPPVIDISRN-DVQPQ 3778
Query: 1496 ---NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKC 1550
N+ + C G P P + W ++GK++ + E + C
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 3838
Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
+A ND G E V+ + PV+++ +++ IK +G+ + G P P++ W K
Sbjct: 3839 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA---LGETITLFCNASGNPYPQLKWAKG 3895
Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
G+ L D K + + I LK++ YT +A N AGTS V++ V P
Sbjct: 3896 GS-LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEIN 3954
Query: 1670 EGPVIM--REISRESVTIE 1686
+ M R +++S+T++
Sbjct: 3955 RDGIDMSPRLPAQQSLTLQ 3973
Score = 141 bits (341), Expect = 6e-33
Identities = 241/1190 (20%), Positives = 427/1190 (35%), Gaps = 123/1190 (10%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLV 569
I ++K + K + STV C G P P ITWF+ I + + + N L
Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + DAG +TC A N+AG + ++ P +
Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEK--------------------- 2388
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+GIP + + + +++ C + A P I WL G+ + D+ + + +
Sbjct: 2389 -DGIPSDYESQ-------QNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS-ANGQ 2439
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747
+Y L+ T+ K YT +A N G + + + P ++ + + V
Sbjct: 2440 KLYLFKLRETDSSK-----YTCIATNEAGTDKRDFKVSMLVAPSFDEPNIV---RRITVN 2491
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
G L G+P PTITW K+ ++ D + + D+G YT A
Sbjct: 2492 SGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIA 2551
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
NS G + + V P P + R + + V E + +L V + W
Sbjct: 2552 TNSVGSDDLENTLEVIIP------PVIDGERREAVAVIEGFSSELFCDSNSTGV-DVEWQ 2604
Query: 868 RNNEIISPSETITQNF-----DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
++ I+ +F G+ + + + DSG Y C+ N AG+ AR
Sbjct: 2605 KDGLTINQDTLRGDSFIQIPSSGKKMSFLSAR---KSDSGRYTCIVRNPAGE----ARKL 2657
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVI------LECQTSHTVSTK--WYHNKKEISGMDHRE 974
D V + + +T++ + C S + K W + K + D
Sbjct: 2658 FDF-AVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLE-PDSAA 2715
Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEK 1031
G C ++ + LV P F ++ ++ +
Sbjct: 2716 YELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVG 2775
Query: 1032 DVAILEVEINSET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
D +L S + V W E + + + + + L + N + DEG Y C
Sbjct: 2776 DTMLLTCNAESSVPLSSVYWHAHDESV--QNGVITSKYAANEKTLNVTNIQLDDEGFYYC 2833
Query: 1090 ILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
+E+ ++ V+E P + + + + G + T + T + + KDG
Sbjct: 2834 TAVNEAGITKKFFKLIVIE-TPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204
+ S+ + + L I + + G Y+C N + + + E
Sbjct: 2893 RLNESDEVDII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948
Query: 1205 FILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
+I V LT+E P E + +TW ++ + S K + L I + T +
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK-LYIMQATPE 3007
Query: 1262 DQCEYTCVLL-DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPND 1319
D Y+C+ + DA + V PPKI D I + + + + P P
Sbjct: 3008 DADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEI 3067
Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W ++ K I + P + K SL I ++ G Y EN G A+ + V I
Sbjct: 3068 SWFLDGKPILE----MPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEI 3123
Query: 1378 LDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
+ P ++ ++ I E GN + ++ E T++ + T
Sbjct: 3124 SEPPRVVMASEVMRVVEGRQTTI---RCEVFGNPEPVVNWLKDGEPYTSDLLQF----ST 3176
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
+ S +L+ + Y + + S+TT +V + P +E + + +
Sbjct: 3177 KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV-----LVPPRIEDEERVLQGKEG 3231
Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+ C G P P VTW R+GK+++ R Y CIA N+
Sbjct: 3232 NTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIR------NATRADEGKYSCIASNEA 3285
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G ++ + KP T + G+ + I+G P P + W K G D
Sbjct: 3286 GTAVADFLIDVFTKP--TFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMD 3343
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
NI + + I + +R YT A+N+ G S + + VY KP
Sbjct: 3344 ---NIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390
Score = 138 bits (335), Expect = 3e-32
Identities = 248/1116 (22%), Positives = 432/1116 (38%), Gaps = 104/1116 (9%)
Query: 599 IVEAPLSDHGSEMT-VXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLEC 655
I +A ++G M V D+LE PP F + Q + + I+L+C
Sbjct: 1702 ITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE--PPVFVEPVFEANQKLIGNNPIILQC 1759
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P+P + W G ++ + S + + S+L+I + + + A N+
Sbjct: 1760 QVTGNPKPTVIWKIDGNDV----DKSWLFDESL----SLLRIEKLTG-KSAQISCTAENK 1810
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKP 774
G AS ++ P E + I R+ E++ L V +G+ + ITW K P
Sbjct: 1811 AGTASRDFFIQ---NIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ--ITWMKQGLP 1865
Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPP 833
+ D +TIL + E +YT A N+ G +++ V+ P +NA
Sbjct: 1866 LTENDAIFTLDNTRLTILNANR-DHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVT 1924
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
L IN +EI L NP P+ W N + P E + F N +V+
Sbjct: 1925 LEINEGEEII--------LTCDAEGNPTPTAKWDFNQGDL-PKEAV---FVNNNHTVVVN 1972
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVILECQT 952
NV ++ +G YKC A+N G++ V + K F L +S T +++ LEC
Sbjct: 1973 NV-TKYHTGVYKCYATNKVGQAVKTINVHVRT-KPRFESGLTESELTVNLTRSITLECDV 2030
Query: 953 SHT--VSTKWYHNKKE-ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ET 1006
V W N K ++ D + + GR D G C V ++ T
Sbjct: 2031 DDAIGVGISWTVNGKPFLAETDGVQTLAGGR--FLHIVSAKTDDHGSYACTVTNEAGVAT 2088
Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065
T + + P + + ++ V E + +L E+ + VV W +DG +P +
Sbjct: 2089 KTFNLFVQVPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG---RPVGDLKSV 2145
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK-------V 1118
+ ++ I + + +G Y C+ +++ TAE++ +IITR QK
Sbjct: 2146 QVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEIS---FDVDIITRPMIQKGIKNIVTA 2202
Query: 1119 NKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDLDDAG 1174
KG F+ + + W ++ I + ++T ++L I + +D G
Sbjct: 2203 IKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEG 2262
Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETL------- 1225
+YSC V N E S +F T+ +P I++ VE TL
Sbjct: 2263 QYSCRVKND-------AGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGK 2315
Query: 1226 ---DVTWYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-- 1278
D+TW+K IE+ ++ L I + E D +YTC ++ + +
Sbjct: 2316 PEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQD 2375
Query: 1279 LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
+ V V+ P D +Y ++ V + A P W+ K ++ K K S
Sbjct: 2376 VNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS 2435
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSS 1396
+ + L + K+ TD+ Y N G + V++L PS +PNI+ I +S
Sbjct: 2436 ANGQ--KLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPS-FDEPNIVRRITVNS 2492
Query: 1397 IN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
N P S I ++ + I+ + + + Q I + + R+ A
Sbjct: 2493 GNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGR-QLQISKTEGSDQGRYTCIA 2551
Query: 1456 VNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
N V D T E VI + ++ V ++ ++E D T + + +
Sbjct: 2552 TNSVGSDDLENTLEVIIPPVIDGERREAVAV---IEGFSSELFCDSNSTGVDVEWQKDGL 2608
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
T +D + + + Y CI N GE + P I
Sbjct: 2609 TINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSI 2668
Query: 1574 T--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVI 1630
+ +S+ +I Q + V+ G P P+V W + LE D Y +T +T +
Sbjct: 2669 SDELSSANI-QTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET--L 2725
Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+I + H+ YT EA N G + + ++V P
Sbjct: 2726 KIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPP 2761
Score = 132 bits (319), Expect = 3e-30
Identities = 240/1100 (21%), Positives = 415/1100 (37%), Gaps = 121/1100 (11%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
DI+E PP+ P+ Y + + L C + P+P++ W FKG ++ D V +S
Sbjct: 606 DIME--PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDS 663
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
L I + EGTY A+++ G+A L + T PP+V M+V
Sbjct: 664 ------KFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLAT----PPKVEIIQNKMMV 713
Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
+G+ V + + G P P I W KN K + + + I+ K +D G Y+
Sbjct: 714 GRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKD-EDAGAYSC 772
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
EN G A ++V P I + V + + L P P I
Sbjct: 773 VGENMAGKDVQVANLSV-------GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIE 825
Query: 866 WYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W + N +++ + TQ DG L+IT+ E D G + C+A N+ G+ S + +
Sbjct: 826 WQKGNVLLATLNNPRYTQLADG---NLLITDAQIE-DQGQFTCIARNTYGQQSQSTTLMV 881
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGR 980
+ H+ + EG+ + L C + S W + K + + I EG
Sbjct: 882 TGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVE--EGPTIKIEGG 939
Query: 981 XXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD---FE-----VK 1029
D G CI V ST+ + + I PEF+ K + F+ +
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 1030 EKDVAILE---------------VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
EK VA++ V + + W DG I P N DF L
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITP--NSRDFTVTAD-NTL 1056
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132
+R G Y+C + + E T + + + N F I
Sbjct: 1057 IVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVY 1116
Query: 1133 GD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCT 1186
GD ++ W D + F+ + + DG L I + + G ++C GN T
Sbjct: 1117 GDPKPVITWLLD--DKPFTEGV-VNEDG---SLTIPNVNEAHRGTFTCHAQNAAGNDTRT 1170
Query: 1187 AILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV---TW-YKKKSVIEDTEK 1241
LTV P+IN E I + N D + +E P + L W Y+ + +
Sbjct: 1171 VTLTVHTTPTIN--AENQEKIAL-QNDD--IVLECPAKALPPPVRLWTYEGEKIDSQLIP 1225
Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
T+ D L+++ ++ + C + L + + + V E P I + +
Sbjct: 1226 HTIRED---GALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
+G + + P+ W N I K K S+D+ +L I + + D G Y
Sbjct: 1283 VKGFTIEIPCRATGVPEVIRTWNKNG-IDLKMDEKKFSVDN-LGTLRIYEADKNDIGNYN 1340
Query: 1360 LRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYV 1416
+ N G + + +V + + P P + N + + + C+ E + T
Sbjct: 1341 CVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG 1400
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+ DT ++ + T IQ+ + + A N ++A+ ++
Sbjct: 1401 IAI-GTDTKGYVVESDGTLV---IQSASVEDATIYTCKASNPAGKAEAN--------LQV 1448
Query: 1477 TKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYEN 1531
T I SP ++ P + + + + L C P P+++WY + K L KT+ T ++
Sbjct: 1449 TVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD 1508
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----G 1587
+ YKC+A N GE S Q + ++ ++ ++ K K KV G
Sbjct: 1509 KRKLHVFKAKITDSGVYKCVARNAAGEGSKS----FQVEVIVPLNLDESKYKKKVFAKEG 1564
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+E + + G P P++ W +G +E K+Y T + + + Y
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCV 1624
Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666
A + ++V L V P
Sbjct: 1625 AQSKGNILDIDVELSVLAVP 1644
Score = 125 bits (302), Expect = 3e-28
Identities = 172/797 (21%), Positives = 313/797 (39%), Gaps = 68/797 (8%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
I T + PKA G +I+L+C ++ P P + W +G++ VP+++ + +
Sbjct: 3392 IDETIDQTPKAV---AGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN----- 3442
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
LKI +V G Y+ +AVN G + ++ G+ P V + V + ++
Sbjct: 3443 -YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEV-IGK--PTFVRKGGNLYEVIENDT 3498
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+ + V P P+I+W + +KPV S S + K+ D G Y +A N
Sbjct: 3499 ITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEA 3558
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G ++ ++ + P + + I I + TI L ++ P P + W +N
Sbjct: 3559 GTSDIDLILKILVPPK--IDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGM 3613
Query: 872 IISPSET---ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
I+ +++ + QN + IE V D G Y C A+N GK+SH + + +
Sbjct: 3614 DINMTDSRVILAQNNETFGIENV-----QVTDQGRYTCTATNRGGKASHDFSLDV-LSPP 3667
Query: 929 TFVKHLQKSYETEEGKTVILECQ-------TSHTVSTKWYHNKKEISG--MDHREIIQEG 979
F H + EG T+ L C + W + + + G D+ +I +G
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVA 1034
R + G+ CI ++ E S V+ P I R +V
Sbjct: 3728 R--KLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPT 3785
Query: 1035 ILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
I+ + + W ++G+ + +N ++G + ++ +R S H G++SC+ +
Sbjct: 3786 IMRCAVTGHPFPSIKWLKNGKEVTDDEN-IRIVEQGQVLQI-LRTDSDH-AGKWSCVAEN 3842
Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS 1149
++ E+ + V PP + + N G T + ++W K GS I F
Sbjct: 3843 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLI-FD 3901
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPE 1204
+ I K +L I D G+Y+C+ N+ T+ +V P IN +
Sbjct: 3902 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD-GIDM 3960
Query: 1205 FILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+PA L + + + W ++ T T+ SD + I + D
Sbjct: 3961 SPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASD--STFIQINNVSLSD 4018
Query: 1263 QCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ YTC + + L V+VV+ P ++ ++ G + + +P P
Sbjct: 4019 KGVYTCYAENVAGSDNLMYNVDVVQAP--VISNGGTKQVIEGELAVIECLVEGYPAPQVS 4076
Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
W+ N ++ + + LTI + + D+GIY N G A + +L
Sbjct: 4077 WLRNGNRVETGVQGVRYV-TDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 4135
Query: 1381 PS-PPGKPNILEIDSSS 1396
P P +L S S
Sbjct: 4136 PKIITSTPGVLTPSSGS 4152
Score = 118 bits (285), Expect = 3e-26
Identities = 204/945 (21%), Positives = 362/945 (38%), Gaps = 86/945 (9%)
Query: 651 ILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
I LEC + IP+PD+ W G +I + D + +A ++ I NV+ +G YT
Sbjct: 3592 IYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNE------TFGIENVQVTDQGRYT 3645
Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILS-----AQVVGNPR 763
A NR G+AS L + + PP+ I + I R+G+++ L+ A+ + +
Sbjct: 3646 CTATNRGGKASHDFSLDVLS----PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 764 PTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++W K+++ + T + D +TI + +++ G+YT A N G A +
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQAS-LENAGLYTCIALNRAGEASLEFKV 3760
Query: 821 TVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
+ P P + I+R Q + TI A VT +P PSI W +N + ++ E
Sbjct: 3761 EILSP------PVIDISRNDVQPQVAVNQPTIMRCA-VTGHPFPSIKWLKNGKEVTDDEN 3813
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
I G+ ++++ T+ D +G + CVA N AG + +DV V +
Sbjct: 3814 IRIVEQGQVLQILRTDSDH---AGKWSCVAENDAGVKE--LEMVLDVFTPPVVSVKSDNP 3868
Query: 939 ETEEGKTVILECQTSHTV--STKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVG 995
G+T+ L C S KW I D I +G DVG
Sbjct: 3869 IKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKG--ARLDIPHLKKTDVG 3926
Query: 996 VIKC-IVKDQETSTMLVVKETI--PEFIRKLQDFEVK---EKDVAILEVEINSETADVVW 1049
C + TS V + + PE R D + ++ + + + + W
Sbjct: 3927 DYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRW 3986
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL 1105
+G + + I N S+ D+G Y+C + ++ V VV+
Sbjct: 3987 TLNGTALTHSTPGITVASDSTF--IQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQA 4044
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS-NHIQLTIDGKKQKL 1163
P +I+ ++V +G A E + A V W ++G+ ++ ++ DG+ L
Sbjct: 4045 P--VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM--L 4100
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAY-LTVEI 1220
I + D+G Y C N +A T+E + +L P++ + L +
Sbjct: 4101 TIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV 4160
Query: 1221 ---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
PD ++W + I+D E I TL I K E+ Y C +
Sbjct: 4161 RGYPDPI--ISWTLNGNDIKDGENGHTIG--ADGTLHIEKA-EERHLIYECTAKNDAGAD 4215
Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
T + V+ + P R G++ + + ++ W N + +
Sbjct: 4216 TLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLI 4274
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
S D K + ++ +D G Y N G+A + N+ + P +P +
Sbjct: 4275 FSEDYKLIKILSTRL--SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG 4332
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAY 1454
W E I +Y + E+ T + TK ++ I ++ + + +
Sbjct: 4333 DQVTLWCEASGVPQPAITWY--KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCK 4390
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
A N V + E + +I P V N++T P + + L+C G+P+P ++
Sbjct: 4391 AENWV--ASTEEDIDLIVMIP------PEVVPERMNVSTNPRQTVFLSCNATGIPEPVIS 4442
Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGE 1558
W RD Y+ Y CIA +D G+
Sbjct: 4443 WMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ 4487
Score = 115 bits (277), Expect = 3e-25
Identities = 167/808 (20%), Positives = 317/808 (39%), Gaps = 71/808 (8%)
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957
D+G+Y+C ++ G S RV ++ G+ L C T V
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFG--VRNVSVPLGEAAFLHCSTRSAGEVE 550
Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKE 1014
+W + + E + D GV +C+ ++ T M +
Sbjct: 551 IRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608
Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
P QD ++ L E + +V W G + N Y ++ +
Sbjct: 609 EPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLL---NDYKYQVGQDSKF 665
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIEL 1130
LYIR+ + HDEG Y C ++ A T ++ PP++ V +G++ +FE +
Sbjct: 666 LYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKT 725
Query: 1131 TKGDA--LVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
+G +RWFK+G + I+ ++I++ + +L I +DAG YSC VG +
Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKIN----EGQLHIMGAKDEDAGAYSC-VGENMAGK 780
Query: 1188 ILTVEEPSINFTLRLPEFILVP----ANTDAYLTVE---IPDETLDVTWYKKKSVIE--D 1238
+ V S+ R+P I P N + +T++ + ++ W K ++ +
Sbjct: 781 DVQVANLSVG---RVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLN 837
Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIVDY 1293
++T ++D L+I +DQ ++TC+ + ++STT + +V P +
Sbjct: 838 NPRYTQLAD---GNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS--PVLGHV 892
Query: 1294 EREYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
E ++ G D+TL V P+P+ WI + K +++ K I+ + L ++
Sbjct: 893 PPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIK--IEGGGSLLRLRGGNP 950
Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKP----SPPG----KPNILEIDSSSINICWDEP 1404
D G Y + G++ + +NV ++ KP P G KP I +D + +
Sbjct: 951 KDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTH 1010
Query: 1405 E-NTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRA---YA-VNE 1458
+ G I VV W + + IT N+ +A Y+ V
Sbjct: 1011 DVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYT 1070
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
++++ E I+ + +P + + ++ + C G P+P +TW D
Sbjct: 1071 CQATNSAGDNEQKTTIR--IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128
Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
K + + C A N G + + + P I N+
Sbjct: 1129 DKPF--TEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ + D+ ++ + +PPP +W G K+ D + T + + ++ +K
Sbjct: 1187 E--KIALQNDDIVLECPAKALPPPVRLWTYEGEKI--DSQLIPHTIREDGALVLQNVKLE 1242
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ + + SN AG S+ TL V++KP
Sbjct: 1243 NTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270
Score = 104 bits (250), Expect = 6e-22
Identities = 120/542 (22%), Positives = 223/542 (41%), Gaps = 36/542 (6%)
Query: 1227 VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
+TWY + + ++ FT+ +D TLI+RK + YTC ++ + K + +
Sbjct: 1032 ITWYLDGRPITPNSRDFTVTAD---NTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
P I + + + T+ D P+P W+++ K + + ++ S
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTE------GVVNEDGS 1142
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
LTI V G + +N G+ + +T+ P+ + N +I + +I + P
Sbjct: 1143 LTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE-NQEKIALQNDDIVLECP 1201
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDI 1461
+ + E ++ID+ + I +QN+K ++ F N E +
Sbjct: 1202 AKALPPPVRLWTYEGEKIDS-QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL 1260
Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
S E K+I E P V +K T IE+ C GVP+ TW ++G
Sbjct: 1261 SYTLTVHEKPKIISEV----PGVVDVVKGFT------IEIPCRATGVPEVIRTWNKNGID 1310
Query: 1522 LKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
LK K + +N Y C+ N+ G + + V +Q+ P+I S +
Sbjct: 1311 LKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQT 1370
Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
VGD + +E PP V W++ G + D + + + T VI+ ++
Sbjct: 1371 -NNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE--D 1427
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-EL 1698
++ YT +ASN AG + + + V P + V+ +E +ES P+ L ++
Sbjct: 1428 ATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQI 1487
Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP 1757
+ Y +K D+ K +D R + + K +++ +A+N G S++ + E
Sbjct: 1488 SWYLNDKPLIDDKTSWKTSDDKRKLHVF---KAKITDSGVYKCVARNAAGEGSKSFQVEV 1544
Query: 1758 IV 1759
IV
Sbjct: 1545 IV 1546
Score = 86.2 bits (204), Expect = 2e-16
Identities = 119/600 (19%), Positives = 229/600 (38%), Gaps = 57/600 (9%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++ G P F ++V G D+ L C + + I W+ GE+I+ ++
Sbjct: 425 VIVGGPRAFMSPIHQEFV--GRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDT- 481
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
SV I + G Y ++ G S+ K + +E P I ++++ V
Sbjct: 482 -----SVWTIPELSLKDAGEYECRVISNNGNYSV----KTRVETRESPPEIFGVRNVSVP 532
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
GE+ L I W + V P T+ + D GVY A
Sbjct: 533 LGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMA 592
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N+ G++ + + EP P Q++ + + L +P P + WY
Sbjct: 593 RNAGGMSTRKMRLDIMEPPSVKVTP-------QDVYFNMREGVNLSCEAMGDPKPEVHWY 645
Query: 868 -RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ +++ + G++ + + + D G Y+C A + AG+ AR T D+
Sbjct: 646 FKGRHLLNDYKYQV----GQDSKFLYIRDATHHDEGTYECRAMSQAGQ----ARDTTDLM 697
Query: 927 KVT--FVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRX 981
T V+ +Q G V EC+T +W+ N K++ D I EG+
Sbjct: 698 LATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ- 756
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKLQDFEVK-EKDVAILE 1037
D G C+ ++ + V + +P I V E+ V +
Sbjct: 757 --LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQC 814
Query: 1038 VEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093
+ + ++ W++ ++ N +Y G+ L I + + D+G+++CI R+
Sbjct: 815 LAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGN---LLITDAQIEDQGQFTCIARNTYG 871
Query: 1094 -ESCTAEVTVVELPPEIITRL-QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149
+S + + V L ++ + +++ +G T + G + W KD ++
Sbjct: 872 QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG 931
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
I+ I+G L++ + D G+Y+C + + L + I + PEF+ P
Sbjct: 932 PTIK--IEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLI----KKPEFVYKP 985
Score = 85.8 bits (203), Expect = 3e-16
Identities = 108/505 (21%), Positives = 186/505 (36%), Gaps = 47/505 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V EG ++EC + P P ++WL G + V +D M L I +
Sbjct: 4055 VIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM----LTIIEARSLD 4109
Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESVILSAQVVGNPR 763
G Y A N G A L++ P++I ++ G L V G P
Sbjct: 4110 SGIYLCSATNEAGSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPD 4165
Query: 764 PTITWCKNNKPVKALPTKSDGDT-HSI----TILKPKKVKDEGVYTLKAENSEGIAETSA 818
P I+W N +K DG+ H+I T+ K + +Y A+N G
Sbjct: 4166 PIISWTLNGNDIK------DGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGAD---- 4215
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
T+E P + P + + + I E GT ++ + +W +N + PS
Sbjct: 4216 --TLEFPVQTIVAPKISTSGNRYINGSE-GTETVIKCEIESESSEFSWSKNGVPLLPSNN 4272
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
+ + D + I+++ T + D G+Y C A+N AG ++ + ++V + ++
Sbjct: 4273 LIFSEDYKLIKILSTRLS---DQGEYSCTAANKAGNATQ--KTNLNVGVAPKIMERPRTQ 4327
Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
+G V L C+ S + WY + + ++ E + GV
Sbjct: 4328 VVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT-KKKSVIFSSISPSQAGV 4386
Query: 997 IKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD 1052
C ++ ST + ++ PE + + + + L V+ W RD
Sbjct: 4387 YTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRD 4446
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEI 1109
I KY L IRN D+G Y CI + ++ T +V P +
Sbjct: 4447 SNIAIQNNEKYQILG----TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGD 1134
+ + KG E + +GD
Sbjct: 4503 PAPIWVECDEKGKPKKTEYMIDRGD 4527
Score = 75.8 bits (178), Expect = 3e-13
Identities = 109/530 (20%), Positives = 199/530 (37%), Gaps = 41/530 (7%)
Query: 1165 IYDCDLDDAGEYSCEV----GN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + L DAGEY C V GN S T + T E P F +R + VP A+L
Sbjct: 486 IPELSLKDAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCS 542
Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276
+++ W + + + + + TL I T D Y C+ +A ST
Sbjct: 543 TRSAGEVEIRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMST 600
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
K++++++E PP + ++ V L + P+P W + + K
Sbjct: 601 RKMRLDIME-PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHL--LNDYKY 657
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
+ S L I+ + D G Y+ R + G A ++ + P N + +
Sbjct: 658 QVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGD 717
Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ + I ++ I ++I I + Q I K + +
Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIK---INEGQLHIMGAKDEDAGAYSCVG 774
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
N + +V + + PT+ + + + L C+ G+P P++ W
Sbjct: 775 ENMAG--------KDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW 826
Query: 1516 YRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQ 1569
+ L T + T + CIA N +G+ T V G+
Sbjct: 827 QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS 886
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
+ + E+ Q + D L V+ G P P ++W K+ +E I + S+
Sbjct: 887 PVLGHVPPEE--QLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGP--TIKIEGGGSL 942
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMR 1676
+R++ KYT A + AG S++ + +++ KP KPEG ++ +
Sbjct: 943 LRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFK 992
Score = 66.1 bits (154), Expect = 3e-10
Identities = 55/236 (23%), Positives = 101/236 (42%), Gaps = 19/236 (8%)
Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
I+ LSD G E + ++ G+ P ++P+ Q V +G + L C
Sbjct: 4284 ILSTRLSDQG-EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 4342
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--RE 716
+P+P I W +K E++ + + E+ SV+ +++ Q G YT A N
Sbjct: 4343 GVPQPAITW-YKDNELLTNTGVD---ETATTKKKSVI-FSSISPSQAGVYTCKAENWVAS 4397
Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
E + +++ I PP+V+ ++ ++V LS G P P I+W +++
Sbjct: 4398 TEEDIDLIVMI------PPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAI 4451
Query: 777 ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
K G T +I + P D+G Y A++ G + + V +P++ A
Sbjct: 4452 QNNEKYQILGTTLAIRNVLP---DDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPA 4504
Score = 64.1 bits (149), Expect = 1e-09
Identities = 125/609 (20%), Positives = 232/609 (38%), Gaps = 70/609 (11%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G+ +C++E + +W + + PS + ++ +D + ++ + D G ++
Sbjct: 4241 EGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNL-IFSEDYKLIKILSTRL--SDQGEYS 4296
Query: 583 CVAKNAAGFASSTTEL-------IVEAPLSD---HGSEMTVXXXXX-----XXXXXXXAD 627
C A N AG A+ T L I+E P + G ++T+ +
Sbjct: 4297 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 4356
Query: 628 IL--EGIPPTFSKKPKA---QYVDEGSDILLECRL---VAIPEPDIAWLFK-GEEIVPDE 678
+L G+ T + K K+ + + C+ VA E DI + E+VP+
Sbjct: 4357 LLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPER 4416
Query: 679 -NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737
N+S + + C+ I + N E L L I+ +
Sbjct: 4417 MNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGF 4476
Query: 738 IEPLKSMIVRQGESVILSAQVVGNP--RPTITW--C-KNNKPVKALPTKSDGDT--HSIT 790
+ G+ + +V P RP W C + KP K GDT +
Sbjct: 4477 YHCIAKS--DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQ 4534
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+L K V+D + A +S + + +A P FI + + T +
Sbjct: 4535 LLPWKDVEDSSLNGSIAYRCMPGPRSSRTVLL------HAAPQ-FIVKPKNTTAAIGAIV 4587
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
+L P P+ITW ++ ++I S+ F+ L +T ++S DSG+Y C+A N
Sbjct: 4588 ELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT-LNSTSDSGEYTCMAQN 4641
Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN----KKE 966
S G S+ A + +D + K S + E +++ W +N K
Sbjct: 4642 SVGSSTVSAFINVDNNILPTPK--PSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 4699
Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRKL 1023
++G+ + G D+ + C V+++ + + E +PE ++ +
Sbjct: 4700 LAGI---HFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPHLTSAFEGVPE-VKTI 4755
Query: 1024 QDFEVKEKDVAILEVEINSE--TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
EV D +L+ E+ S+ T VVW ++ + + Y L + N
Sbjct: 4756 DKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPN----NSLVLLNVEK 4811
Query: 1082 HDEGEYSCI 1090
+DEG Y C+
Sbjct: 4812 YDEGVYKCV 4820
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 31/294 (10%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F KPK G+ + L C P P I W G+ ++ D +A S
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAY--------S 4620
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
LK+T G YT +A N G +++ + + P+ K++ +VI
Sbjct: 4621 HLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV------AVI 4674
Query: 754 LSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
+ +TW N P+ K L + S+ IL +K D +YT K N
Sbjct: 4675 TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITWYRN 869
+ E E + ++ V ++ L VT +P+ + + W +N
Sbjct: 4735 RRHSIPHLTSAFEGVPE--------VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN 4786
Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
++ + + I + N LV+ NV+ + D G YKCVASNS GK+ ++ +
Sbjct: 4787 DQKMLDDDAI---YVLPNNSLVLLNVE-KYDEGVYKCVASNSIGKAFDDTQLNV 4836
Score = 57.6 bits (133), Expect = 9e-08
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 19/271 (7%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
PQ I K+ G V L G P PTITW K+ K ++ + +T+
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL--- 4626
Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
D G YT A+NS G + SA I V+ +P IT E+ + +
Sbjct: 4627 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERN--QAYS 4684
Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
R +TW N + P +F N LVI + S + GD + +
Sbjct: 4685 R-------GLTW-EYNGVPMPKNLAGIHF-MNNGSLVILDT-SSLKEGDLELYTCKVRNR 4734
Query: 915 SSHG-ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDH 972
H +T E V VK + K E G +V+L+C+ TS ++T K + +D
Sbjct: 4735 RRHSIPHLTSAFEGVPEVKTIDK-VEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDD 4793
Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
+ I D GV KC+ +
Sbjct: 4794 -DAIYVLPNNSLVLLNVEKYDEGVYKCVASN 4823
Score = 56.0 bits (129), Expect = 3e-07
Identities = 61/321 (19%), Positives = 120/321 (37%), Gaps = 22/321 (6%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P + P GS L C + P+P I+W G +I EN I +D
Sbjct: 4136 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGEN-GHTIGAD----- 4189
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
L I ++ + Y A N G +L ++ K + +G
Sbjct: 4190 GTLHIEKAEE-RHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING---SEGTET 4245
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ + + + +W KN P+ + + + + ++ D+G Y+ A N G
Sbjct: 4246 VIKCE-IESESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAG 4304
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A + V P + R + V + + L + P P+ITWY++NE+
Sbjct: 4305 NATQKTNLNV-------GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNEL 4357
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
++ + + + + ++ +++ S +G Y C A N + + + + +
Sbjct: 4358 LT-NTGVDETATTKKKSVIFSSI-SPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 4415
Query: 933 HLQKSYETEEGKTVILECQTS 953
+ S T +TV L C +
Sbjct: 4416 RMNVS--TNPRQTVFLSCNAT 4434
Score = 54.8 bits (126), Expect = 6e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 24/347 (6%)
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
TI ++ DAG Y+ R+ +N G+ V+ V + P P I + + S+ + E
Sbjct: 485 TIPELSLKDAGEYECRVISNNGNYSVKTRVETRESP-----PEIFGVRNVSVPL--GEAA 537
Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA-VNEVDISDA 1464
ST VE + T +V N T+ + N + RA A V E +A
Sbjct: 538 FLHCSTRSAGEVEIRW--TRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNA 595
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
+ + ++ ++ P+V+ +++ E + L+C G P+P+V WY G+ L
Sbjct: 596 GGMST--RKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLN 653
Query: 1525 --AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
++ Y+C A + G+ + + + P + I I+
Sbjct: 654 DYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEI----IQN 709
Query: 1583 KHKVGDEWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
K VG V+ I G P P++ W+KNG L +Y K + I K
Sbjct: 710 KMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDY---IKINEGQLHIMGAKDED 766
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
+ Y+ N AG L V P+ E P +R VT++
Sbjct: 767 AGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQ 813
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C N G+ E + + + + PV + QK + ++ + G P P VIW
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+GN + DK + E S++RI++L S++ + A N AGT+S + ++ P+
Sbjct: 1773 IDGNDV--DKSW--LFDESLSLLRIEKL-TGKSAQISCTAENKAGTASRDFFIQNIAAPT 1827
Query: 1668 -KPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
K EG I RES TI P+ G ++T
Sbjct: 1828 FKNEGD--QETIFRESETITLDCPVSLGDFQIT 1858
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
K +G EC VEGYP PQ++W R ++ Y D + T++ E D+
Sbjct: 4053 KQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII--EARSLDS 4110
Query: 579 GTFTCVAKNAAGFASS--TTELIV 600
G + C A N AG A T E++V
Sbjct: 4111 GIYLCSATNEAGSAQQAYTLEVLV 4134
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
PI + + +T G V+ +C VE P +TWFR+ I D + Y + + TL
Sbjct: 1362 PIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAI--GTDTKGYVVESD-GTL 1418
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
VI+ EDA +TC A N AG A + ++ V A
Sbjct: 1419 VIQSASVEDATIYTCKASNPAGKAEANLQVTVIA 1452
Score = 48.0 bits (109), Expect = 7e-05
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ T E S P V +G C+V G P P + W + +P +
Sbjct: 3116 EQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDG---EPYTSDLL 3172
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ ++ L +RE D GT+TC+A N AG + +TT++ V P
Sbjct: 3173 QFST-KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C A N G + + P I + + HK GD+ + G+P P + WY
Sbjct: 4295 YSCTAANKAGNATQKTNLNVGVAPKI-MERPRTQVVHK-GDQVTLWCEASGVPQPAITWY 4352
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
K+ L N T +K SVI + S + YT +A N ++ ++ L V P
Sbjct: 4353 KDNELLTNTGVDETATTKKKSVI-FSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 4410
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T+ +AP +E+ R + G V C+ G P+P ITW++ ++ + +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET--A 4367
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+++ + P AG +TC A+N +LIV P
Sbjct: 4368 TTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIP 4409
Score = 45.2 bits (102), Expect = 5e-04
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F+ K + G+ V+ C G P P ITW + +I+ S+ F++ Y L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-FEIAYSH-----L 4622
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ D+G +TC+A+N+ G SST +
Sbjct: 4623 KVTLNSTSDSGEYTCMAQNSVG--SSTVSAFI 4652
Score = 44.8 bits (101), Expect = 7e-04
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V C+ G P+P++ W+ + + +Q+ D L IR+ D GT+ C A
Sbjct: 628 VNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSK---FLYIRDATHHDEGTYECRAM 684
Query: 587 NAAGFASSTTELIVEAP 603
+ AG A TT+L++ P
Sbjct: 685 SQAGQARDTTDLMLATP 701
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 508 MAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+AP F E +R G+ C +G P P ITW + I+P+ D +++D
Sbjct: 2475 VAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPN-DRYVFFDAGR- 2532
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGF--ASSTTELIV 600
L I + D G +TC+A N+ G +T E+I+
Sbjct: 2533 -QLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVII 2568
Score = 41.1 bits (92), Expect = 0.008
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 25/102 (24%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
+ VF KPT E VE G + + EC+++G+P+P I+W +K +
Sbjct: 3294 IDVFTKPTFETHETTFNIVE---------GESAKIECKIDGHPKPTISW------LKGGR 3338
Query: 555 DFQMYYDDDNVA------TLVIREVFPEDAGTFTCVAKNAAG 590
F M DN+ TL+I + D G +TCVA N+ G
Sbjct: 3339 PFNM----DNIILSPRGDTLMILKAQRFDGGLYTCVATNSYG 3376
Score = 39.9 bits (89), Expect = 0.019
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
+ KP KN T +EL C G P P +TW +DGK ++ +K
Sbjct: 4573 IVKP-KNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIA-YSHLKVTLNSTS 4630
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGI 1567
Y C+A N G S + +
Sbjct: 4631 DSGEYTCMAQNSVGSSTVSAFINV 4654
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 11/91 (12%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E + P ++ R +G+T CQV G P P +TW R K + F
Sbjct: 3209 TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNG---KEIEQFN---- 3261
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
L IR D G ++C+A N AG A
Sbjct: 3262 ----PVLHIRNATRADEGKYSCIASNEAGTA 3288
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P ++ +C +G P PQ+ W TA+ + + D + I V D G
Sbjct: 3965 PAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ---INNVSLSDKGV 4021
Query: 581 FTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613
+TC A+N AG + + +V+AP+ +G V
Sbjct: 4022 YTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV 4055
Score = 37.9 bits (84), Expect = 0.078
Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 26/201 (12%)
Query: 408 FEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKG 467
FE V R GDT+ + AE+ ++ V + D S Q+ K+ EK
Sbjct: 2763 FEKEREEVVARVGDTMLLTCN--AESSVPLSSVYW---HAHDESVQNGVITSKYAANEKT 2817
Query: 468 WVPAQYLMDENNY---TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPD 523
+D+ + T + + +K KL V E P ++Q + PI +
Sbjct: 2818 LNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIIL---------- 2867
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + +C G P P I + + + S + + +TLVI E G +TC
Sbjct: 2868 GKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIG-----STLVIDNPQKEVEGRYTC 2922
Query: 584 VAKNAAGFASSTTELIVEAPL 604
+A+N AG S +++VE L
Sbjct: 2923 IAENKAG--RSEKDMMVEVLL 2941
Score = 35.9 bits (79), Expect = 0.32
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E +P + +R P G C +I W R A + + +
Sbjct: 512 TRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTER--- 568
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
+ TL I V DAG + C+A+NA G ++ L I+E P
Sbjct: 569 NPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPP 611
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P + W K+G KL D ++ I S +++ S S +YT A N+ G+S+V
Sbjct: 4595 GPPHPTITWAKDG-KLIEDSKFEIA----YSHLKVTLNSTSDSGEYTCMAQNSVGSSTVS 4649
Query: 1658 VTLKV 1662
+ V
Sbjct: 4650 AFINV 4654
Score = 33.9 bits (74), Expect = 1.3
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 523 DGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C EG P P W F Q + K + ++ ++++ T+V+ V G +
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLPKEA----VFVNNNH--TVVVNNVTKYHTGVY 1982
Query: 582 TCVAKNAAGFASSTTELIVEA-PLSDHG---SEMTVXXXXXXXXXXXXADIL-EGIPPTF 636
C A N G A T + V P + G SE+TV D + GI T
Sbjct: 1983 KCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 637 SKKP 640
+ KP
Sbjct: 2043 NGKP 2046
Score = 33.9 bits (74), Expect = 1.3
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+ +++ C+V G P P +TW + + + Q+ + +V E+ G++
Sbjct: 2112 ENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQF-KIVHAEI--AHKGSYI 2168
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
C+AKN G A + ++ I+ P+ G
Sbjct: 2169 CMAKNDVGTAEISFDVDIITRPMIQKG 2195
Score = 33.9 bits (74), Expect = 1.3
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G +V +C+V P + W + K D +Y +N +LV+ V D G +
Sbjct: 4762 NGDSVVLDCEVTSDPLTTHVVWTKNDQ--KMLDDDAIYVLPNN--SLVLLNVEKYDEGVY 4817
Query: 582 TCVAKNAAGFASSTTELIV 600
CVA N+ G A T+L V
Sbjct: 4818 KCVASNSIGKAFDDTQLNV 4836
Score = 32.7 bits (71), Expect = 3.0
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 510 PIFVEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P+FVE + + + + +CQV G P+P + W + S F D++++
Sbjct: 1736 PVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLF-----DESLSL 1790
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593
L I ++ + A +C A+N AG AS
Sbjct: 1791 LRIEKLTGKSA-QISCTAENKAGTAS 1815
Score = 31.5 bits (68), Expect = 6.8
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
TP GS C V GYP P I+W IK ++ D TL I E E
Sbjct: 4147 TPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD---GTLHI-EKAEERHL 4202
Query: 580 TFTCVAKNAAG 590
+ C AKN AG
Sbjct: 4203 IYECTAKNDAG 4213
>AF074901-1|AAC26792.1| 5198|Caenorhabditis elegans hemicentin
precursor protein.
Length = 5198
Score = 213 bits (520), Expect = 1e-54
Identities = 282/1187 (23%), Positives = 464/1187 (39%), Gaps = 142/1187 (11%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + EC +E ITW RQ K Q + + L I + PEDA +++C
Sbjct: 2957 GDPLTLECPIEDTSGVHITWSRQFG--KDGQLDMRAQSSSDKSKLYIMQATPEDADSYSC 3014
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+A N AG A + ++ V P G + EGIPP
Sbjct: 3015 IAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCR-TEGIPP--------- 3064
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
PE I+W G+ I+ ++ + D+ L+I N+K
Sbjct: 3065 -----------------PE--ISWFLDGKPILEMPGVTYK-QGDLS-----LRIDNIKPN 3099
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
QEG YT VA N+ G A ++I EPP+V+ + M V +G + +V GNP
Sbjct: 3100 QEGRYTCVAENKAGRAEQDTYVEI----SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPE 3155
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
P + W K+ +P + S L+ + D G YT A N G ++T+ + V
Sbjct: 3156 PVVNWLKDGEPYTS-DLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV- 3213
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
PP + + + KE T + +VT PVP +TW RN + I + F
Sbjct: 3214 ------LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-------EQF 3260
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
N L I N + D G Y C+ASN AG + A IDV K TF H + ++ E
Sbjct: 3261 ---NPVLHIRNA-TRADEGKYSCIASNEAGTAV--ADFLIDVFTKPTFETH-ETTFNIVE 3313
Query: 943 GKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
G++ +EC+ H T W + + MD+ II R D G+ C+
Sbjct: 3314 GESAKIECKIDGHPKPTISWLKGGRPFN-MDN--IILSPRGDTLMILKAQRFDGGLYTCV 3370
Query: 1001 V------KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE 1054
+Q+ + K I E I + V ++ + + + T V W+R G+
Sbjct: 3371 ATNSYGDSEQDFKVNVYTKPYIDETIDQTPK-AVAGGEIILKCPVLGNPTPTVTWKR-GD 3428
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEIIT 1111
P +++ ++ I + + D G+YSCI +E+ T V P +
Sbjct: 3429 DAVPNDSRHTIVNNYDLK---INSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR 3485
Query: 1112 RLQN-QKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
+ N +V + + T + +T + WF+ + + ++ DG + I
Sbjct: 3486 KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDG--SHITINKAK 3543
Query: 1170 LDDAGEYSC----EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223
L D G+Y C E G S IL + P I+ + + + + A T YL I
Sbjct: 3544 LSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVART-IYLECPISGIP 3602
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
DV W K I T+ +++ T I DQ YTC + K++ +
Sbjct: 3603 QPDVIWTKNGMDINMTDSRVILAQ-NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 3661
Query: 1282 EVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDE-----WIVNSKIIKKCKHTK 1335
+V+ PP+ + + IKR G +TL + D+ W +S+ +
Sbjct: 3662 DVLS-PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDN 3720
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
I LTI + +AG+Y N G A +E V IL SPP +++I +
Sbjct: 3721 VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL---SPP----VIDISRN 3773
Query: 1396 SINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-SVKNITKTQT--------SIQNLKT 1445
+ +P+ N TI+ V + +W+ + K +T + +Q L+T
Sbjct: 3774 DV-----QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRT 3828
Query: 1446 NSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
+S + ++ A N+ + + + + + S + P+K + E I L C
Sbjct: 3829 DSDHAGKWSCVAENDAGVKELEMVLDVF----TPPVVSVKSDNPIKAL----GETITLFC 3880
Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
G P P++ W + G + A+ + + Y C A N G
Sbjct: 3881 NASGNPYPQLKWAKGGSLIFDSPDGARISLKG-ARLDIPHLKKTDVGDYTCQALNAAGTS 3939
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
E S V + P I D+ + + + +G P P++ W NG L +
Sbjct: 3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTP- 3998
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
IT ++ I+I + S YT A N AG+ ++ + V P
Sbjct: 3999 GITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 4045
Score = 194 bits (473), Expect = 6e-49
Identities = 268/1073 (24%), Positives = 421/1073 (39%), Gaps = 82/1073 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
PTF + EG +EC++ P+P I+WL KG +NI ++ D
Sbjct: 3300 PTFETHETTFNIVEGESAKIECKIDGHPKPTISWL-KGGRPFNMDNIILSPRGD------ 3352
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I ++F G YT VA N G++ + + T + + K++ G +I
Sbjct: 3353 TLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGEII 3409
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
L V+GNP PT+TW + + A+P S H TI+ +K V T A I
Sbjct: 3410 LKCPVLGNPTPTVTWKRGD---DAVPNDS---RH--TIVNNYDLKINSVTTEDAGQYSCI 3461
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A A E P F+ + + V E TI + VT P+PSI+W+R ++
Sbjct: 3462 AVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKP 3521
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
+ + + + DG +I + N D G Y C ASN AG S + I V
Sbjct: 3522 VYLYDRYSISPDGSHITI---NKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKS 3578
Query: 933 HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
++ + +T+ LEC S W N +I+ D R I+ +
Sbjct: 3579 NIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNN-ETFGIENVQ 3637
Query: 991 XXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEV------EI 1040
D G C + + + + + PEF I Q +E D L +I
Sbjct: 3638 VTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDI 3697
Query: 1041 NSETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ DV W +D + + D G RKL I S+ + G Y+CI + + A
Sbjct: 3698 ADQVMDVSWTKDSRALDGDLTDNVDISDDG--RKLTISQASLENAGLYTCIALNRAGEAS 3755
Query: 1100 VTV-VEL--PPEI-ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQ 1153
+ VE+ PP I I+R Q N+ T G ++W K+G E+ +I+
Sbjct: 3756 LEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR 3815
Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
+ G Q L+I D D AG++SC + G + +L V P + +++ I
Sbjct: 3816 IVEQG--QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKAL 3872
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
T + + W K S+I D+ IS +K L I + D +YTC
Sbjct: 3873 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQ 3931
Query: 1270 LLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
L+A T++ V V V PP+I + R+ +TL Q P P W +N
Sbjct: 3932 ALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGT 3991
Query: 1327 IIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--S 1382
+ H+ P I S S + I V +D G+Y EN G ++ NV ++ P S
Sbjct: 3992 AL---THSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS 4048
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQ 1441
G ++E + + I C E + ++ ++T V+ +T +I
Sbjct: 4049 NGGTKQVIEGELAVIE-CLVEGYPAPQ---VSWLRNGNRVETGVQ-GVRYVTDGRMLTII 4103
Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
++ S + A NE + + T E V+ KI + T +T L
Sbjct: 4104 EARSLDSGIYLCSATNEAGSAQQAYTLE---VLVSPKIITSTPGV----LTPSSGSKFSL 4156
Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G P P ++W +G +K + + Y+C A ND G
Sbjct: 4157 PCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADT 4216
Query: 1561 TSCVVGIQQKPVITIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
V P I+ S N I G E ++ IE E W KNG L
Sbjct: 4217 LEFPVQTIVAPKISTSGNRYINGSE--GTETVIKCEIES-ESSEFSWSKNGVPLLPSN-- 4271
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
N+ E +I+I + S +Y+ A+N AG ++ + L V P E P
Sbjct: 4272 NLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP 4324
Score = 187 bits (456), Expect = 7e-47
Identities = 248/1061 (23%), Positives = 417/1061 (39%), Gaps = 91/1061 (8%)
Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
G DI L C L + W G E D +V I SD H L IT+ K
Sbjct: 1657 GKDISLSCDLQTESDDKTTFVWSINGSE--SDRPDNVQIPSDGHR----LYITDAKPENN 1710
Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSAQVVGNPR 763
G Y N G+A + L + EPP +EP+ + + +IL QV GNP+
Sbjct: 1711 GKYMCRVTNSAGKAERTLTLDVL----EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPK 1766
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEGIAETSAVITV 822
PT+ W + V KS S+++L+ +K+ + + AEN G A I
Sbjct: 1767 PTVIWKIDGNDVD----KSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFI-- 1820
Query: 823 EEPTEENAEPPLFINRFQEITV-KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
+N P F N + T+ +E TI L V+ ITW + ++ ++ I
Sbjct: 1821 -----QNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWMKQGLPLTENDAI-- 1872
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
F +N L I N + + + Y CVA+N+AG+ S V + V + +K+ + E
Sbjct: 1873 -FTLDNTRLTILNANRDHED-IYTCVANNTAGQVSKDFDVVVQV--LPKIKNAVVTLEIN 1928
Query: 942 EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
EG+ +IL C + T + KW N+ ++ +E + GV KC
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLP----KEAVFVNNNHTVVVNNVTKYHTGVYKC 1984
Query: 1000 IVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWERDG 1053
+ Q T+ V T P F L + E+ + +E + + A + W +G
Sbjct: 1985 YATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNG 2044
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
+ + + G R L+I + D G Y+C + +E+ A T V++PP I+
Sbjct: 2045 KPFLAETDGVQTLAGG--RFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
V + N E+T K + +V W KDG + +Q+ +G Q+ KI +
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEG--QQFKIVHAE 2160
Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIP---DET 1224
+ G Y C N TA ++ + I + + + I +V A L + P D+
Sbjct: 2161 IAHKGSYICMAKNDVGTAEISFDVDIITRPM-IQKGIKNIVTAIKGGALPFKCPIDDDKN 2219
Query: 1225 L--DVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLK 1280
+ W + I+ + E + R L I TE+D+ +Y+C V DA +
Sbjct: 2220 FKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDF 2279
Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KKCKHTKP 1336
V PP I+ D ++ S VTL P+P+ W + + I + P
Sbjct: 2280 KATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIP 2339
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVTILDKPSPPGKPNILEIDS 1394
+ + L I +++ DAG Y +N+ G DV +NV + K G P+ E
Sbjct: 2340 NGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ 2399
Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
+ + P I ++ + + + +++ + + + L+ S ++
Sbjct: 2400 NE-RVVISCPVYARPPAKITWLKAGKPLQSDKFVKT-SANGQKLYLFKLRETDSSKYTCI 2457
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPK 1512
A NE A +KV + + +P+ ++P ++ IT L C G P P
Sbjct: 2458 ATNE-----AGTDKRDFKV---SMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT 2509
Query: 1513 VTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+TW +DG ++ ++ Y CIA N G + + +
Sbjct: 2510 ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIP 2569
Query: 1571 PVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK---EYNITTKEK 1626
PVI E + E + G+ +V W K+G + D + I
Sbjct: 2570 PVIDGERREAVAVIEGFSSELFCDSNSTGV---DVEWQKDGLTINQDTLRGDSFIQIPSS 2626
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+ ++S S +YT N AG + V D PS
Sbjct: 2627 GKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS 2667
Score = 187 bits (456), Expect = 7e-47
Identities = 229/1061 (21%), Positives = 423/1061 (39%), Gaps = 83/1061 (7%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F + K + G + L+C P P I ++ G+ + + + + S
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--------GS 2905
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L I N +K EG YT +A N+ G + +++++ PP++ + ++ V+ G+ +
Sbjct: 2906 TLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLL----PPKLSKEWINVEVQAGDPLT 2961
Query: 754 LSAQVVGNPRPTITWCKN-NKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
L + ITW + K + + +S D + I++ +D Y+ A N
Sbjct: 2962 LECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATP-EDADSYSCIAVNDA 3020
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G AE +TV P P +F + F + T+++ R P P I+W+ + +
Sbjct: 3021 GGAEAVFQVTVNTP------PKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGK 3074
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTF 930
I +T + ++ L I N+ G Y CVA N AG++ V I + +V
Sbjct: 3075 PILEMPGVT--YKQGDLSLRIDNIKPN-QEGRYTCVAENKAGRAEQDTYVEISEPPRVVM 3131
Query: 931 VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
+ + EG+ + C+ + W + + + +++Q +
Sbjct: 3132 ASEVMR---VVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTS----DLLQFSTKLSYLHLR 3184
Query: 988 XXXXXDVGVIKCIV--KDQETSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSET 1044
D G CI K E+ T V+ +P I + + + KE + ++ ++
Sbjct: 3185 ETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 1045 AD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102
V W+R+G+ + E+ + L+IRN + DEG+YSCI +E+ TA
Sbjct: 3245 VPYVTWKRNGK---------EIEQFNPV--LHIRNATRADEGKYSCIASNEAGTAVADFL 3293
Query: 1103 --VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
V P T + +G A E ++ + W K G N + + +
Sbjct: 3294 IDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMDN---IILSPR 3350
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTL-RLPEFILVPANTD 1213
L I D G Y+C NS + + +P I+ T+ + P+ + A +
Sbjct: 3351 GDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGE 3407
Query: 1214 AYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
L + + T VTW + + + + T++++ L I T +D +Y+C+ ++
Sbjct: 3408 IILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNY---DLKINSVTTEDAGQYSCIAVN 3464
Query: 1273 --AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
TT EV+ P + Y + +T+ + P P+ W K +
Sbjct: 3465 EAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPV-- 3522
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
+ + SI + +TI K + +D G Y R N G +D+++ + IL P K NI+
Sbjct: 3523 YLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDIDLILKIL-VPPKIDKSNII 3581
Query: 1391 EIDSSSI--NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
+ + I + P + + + +I+ T+ + I+N++
Sbjct: 3582 GNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIK-ETKIQSPTVEKPLKNIT-TEPNEDIE-LTCIF 1505
R+ A N + + + + + PT+++ IT T P + E +
Sbjct: 3642 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
V K + DG + + R Y CIA N GE V
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGR-KLTISQASLENAGLYTCIALNRAGEASLEFKV 3760
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
I PVI IS D++ + V ++ + G P P + W KNG ++ +D+ NI E
Sbjct: 3761 EILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE--NIRIVE 3818
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ V++I H+ K++ A N AG +E+ L V+ P
Sbjct: 3819 QGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859
Score = 181 bits (440), Expect = 6e-45
Identities = 248/1089 (22%), Positives = 419/1089 (38%), Gaps = 83/1089 (7%)
Query: 632 IPPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
+PPT K K + E S + L C PEPDI W FK E + ENI+ I +
Sbjct: 2285 VPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITW-FKDGEAIHIENIADIIPNG-E 2342
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748
+ + LKIT +K+ G YT A N G + + + T K E + +S +Q
Sbjct: 2343 LNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYES---QQ 2399
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKA 807
E V++S V P ITW K KP+++ K+ + + + K ++ D YT A
Sbjct: 2400 NERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSANGQKLYLFKLRET-DSSKYTCIA 2458
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N G + +++ + + P + R ITV L +P P+ITW
Sbjct: 2459 TNEAGTDKRDFKVSML--VAPSFDEPNIVRR---ITVNSGNPSTLHCPAKGSPSPTITWL 2513
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ I P++ FD +L I+ + D G Y C+A+NS G + + +
Sbjct: 2514 KDGNAIEPNDRYVF-FDAGR-QLQISKTEGS-DQGRYTCIATNSVGSDDLENTLEVIIPP 2570
Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYH-----NKKEISGMDHREIIQEGRX 981
V + +++ EG + L C ++ T V +W N+ + G +I G+
Sbjct: 2571 VIDGER-REAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKK 2629
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEV 1038
D G CIV++ + + P +L + + V V
Sbjct: 2630 MSFLSARKS--DSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANI-QTIVPYYPV 2686
Query: 1039 EIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
EIN S V W D + ++P Y+ G K+ + V G Y+C ++
Sbjct: 2687 EINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV--RSQVEHAGTYTCEAQN 2744
Query: 1094 ESCTAE---VTVVELPPEIITRLQNQKVNKGNKA--TFEIELTKGDALVRWFKDGSEIQF 1148
A + V PP + G+ T E + + V W +Q
Sbjct: 2745 NVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQ- 2803
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLP 1203
+ I ++ L + + LDD G Y C N K ++ +E P +L
Sbjct: 2804 NGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLY 2863
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
IL T P T + + K + ++++ +I TL+I ++ +
Sbjct: 2864 PIILGKRLTLDCSATGTPPPT--ILFMKDGKRLNESDEVDIIGS----TLVIDNPQKEVE 2917
Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
YTC+ + +S + VEV+ PPK+ ++ G +TL + + W
Sbjct: 2918 GRYTCIAENKAGRSEKDMMVEVL-LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW 2976
Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
+ S KS L I + DA Y N+ G A+ VT+ P
Sbjct: 2977 SRQFGKDGQLDMRAQSSSDKS-KLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Query: 1382 SPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
G + EI + + E I +++ + + I ++ K I
Sbjct: 3036 KIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFL-DGKPILEMPGVTYKQ-GDLSLRI 3093
Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
N+K N R+ A N+ + +E Y ++ + P V + +
Sbjct: 3094 DNIKPNQEGRYTCVAENK---AGRAEQDTYVEIS-----EPPRVVMASEVMRVVEGRQTT 3145
Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-XYKCIAFNDHGEV 1559
+ C G P+P V W +DG+ + + + Y CIA N GE
Sbjct: 3146 IRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGES 3205
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+T+ V + P I +E+ + K G+ ++V + G P P V W +NG ++E ++
Sbjct: 3206 QTTTDVEVLVPP--RIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIE---QF 3260
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
N V+ I+ R+ KY+ ASN AGT+ + + V+ KP+ +
Sbjct: 3261 N-------PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE 3313
Query: 1680 RESVTIEWK 1688
ES IE K
Sbjct: 3314 GESAKIECK 3322
Score = 180 bits (437), Expect = 1e-44
Identities = 229/1065 (21%), Positives = 423/1065 (39%), Gaps = 85/1065 (7%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP + V EG + C + PEP + WL GE D ++ +
Sbjct: 3126 PPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSD-----LLQFSTKL-- 3178
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
S L + GTYT +A N+ GE+ +++ PP++ + + + ++G +
Sbjct: 3179 SYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLV----PPRIEDEERVLQGKEGNTY 3234
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ QV G P P +TW +N K ++ + + ++ DEG Y+ A N G
Sbjct: 3235 MVHCQVTGRPVPYVTWKRNGKEIEQF--------NPVLHIRNATRADEGKYSCIASNEAG 3286
Query: 813 IAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
A +I V +PT E E + E + K+ ++ +P P+I+W +
Sbjct: 3287 TAVADFLIDVFTKPTFETHE--------TTFNIVEGESAKIECKIDGHPKPTISWLKGGR 3338
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
+ + I + G+ + ++ D G Y CVA+NS G S +V + K
Sbjct: 3339 PFN-MDNIILSPRGDTLMILKA---QRFDGGLYTCVATNSYGDSEQDFKVNV-YTKPYID 3393
Query: 932 KHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
+ + ++ + G +IL+C + T + W + I+
Sbjct: 3394 ETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNN---YDLKINSV 3450
Query: 990 XXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEINSE-T 1044
D G CI V + T E I P F+RK + +EV E D ++ + S
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
+ W R G+ ++Y G + I + D G+Y C +E+ T+++ +
Sbjct: 3511 PSISWFR-GDKPVYLYDRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLIL 3567
Query: 1103 -VELPPEI--ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDG 1158
+ +PP+I + N E ++ V W K+G +I ++ ++ +
Sbjct: 3568 KILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS-RVILAQ 3626
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA-------ILTVEEPSINFTLRL--PEFILVP 1209
+ I + + D G Y+C N A +L+ E I+ T E +
Sbjct: 3627 NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTIT 3686
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
L +I D+ +DV+W K ++ D ISD R L I + + ++ YTC
Sbjct: 3687 LTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISD-DGRKLTISQASLENAGLYTC 3745
Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
+ L+ L+ +V P ++D R + ++ + P P+ +W+ N
Sbjct: 3746 IALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNG 3805
Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
K + ++ + I + L I + ++ AG + EN+ G ++EM + + P
Sbjct: 3806 KEVTDDENIR--IVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSV 3863
Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
K N ++ +I + + N + + D+ + + ++ + I +LK
Sbjct: 3864 KSDNPIKALGETITLFCNASGNP-YPQLKWAKGGSLIFDSPDGARI-SLKGARLDIPHLK 3921
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
+ A+N S+AS + + V+ +I ++ + + + L C+
Sbjct: 3922 KTDVGDYTCQALNAAGTSEASVSVD---VLVPPEINRDGIDMSPR---LPAQQSLTLQCL 3975
Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
G P P++ W +G L T T + Y C A N G
Sbjct: 3976 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 4035
Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
V + Q PV ISN KQ + G+ ++ ++EG P P+V W +NGN++E + +
Sbjct: 4036 MYNVDVVQAPV--ISNGGTKQVIE-GELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GV 4091
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ I E + S Y A+N AG++ TL+V P
Sbjct: 4092 RYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 4136
Score = 177 bits (431), Expect = 7e-44
Identities = 270/1198 (22%), Positives = 453/1198 (37%), Gaps = 124/1198 (10%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V +C G P P+I W + ++ + + Y L+I + ED G FTC+A+
Sbjct: 810 VTLQCLAVGIPPPEIEWQKGNVLLATLNNPR--YTQLADGNLLITDAQIEDQGQFTCIAR 867
Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
N G S +T L+V +S +L +PP + +
Sbjct: 868 NTYGQQSQSTTLMVTGLVS---------------------PVLGHVPP-------EEQLI 899
Query: 647 EGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG D+ L C +V P+P I W+ K ++ V +E ++ IE S+L++ E
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWI-KDDKPV-EEGPTIKIEGG----GSLLRLRGGNPKDE 953
Query: 706 GTYTVVAVNREGEASLPI-VLKIKTGE----KEPPQVIEPLKSMI-------------VR 747
G YT +AV+ G ++L I V IK E E V +P S + V
Sbjct: 954 GKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVL 1013
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKD-EGVYTL 805
GE + V G P P ITW + +P+ P D T T++ K K GVYT
Sbjct: 1014 DGEGFAIPCVVSGTPPPIITWYLDGRPI--TPNSRDFTVTADNTLIVRKADKSYSGVYTC 1071
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
+A NS G E I + P+ + + V +P P IT
Sbjct: 1072 QATNSAGDNEQKTTIRI-------MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVIT 1124
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
W + + T+ E+ L I NV +E G + C A N+AG + +T+
Sbjct: 1125 W------LLDDKPFTEGVVNEDGSLTIPNV-NEAHRGTFTCHAQNAAGNDTRTVTLTVHT 1177
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS---HTVSTKWYHNKKEISGMDHREIIQEGRXX 982
++ +K + ++LEC V Y +K S + I ++G
Sbjct: 1178 TPTINAENQEKI--ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG--- 1232
Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
+ GV C V + L T+ E + + + V +EI
Sbjct: 1233 ALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPC 1292
Query: 1043 ETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
V W ++G +K + K+ + G +R I +D G Y+C++ +E+ T
Sbjct: 1293 RATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR---IYEADKNDIGNYNCVVTNEAGT 1349
Query: 1098 AEVTV---VELPPEIITRLQ-NQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152
+++T V+ PP I+ Q N G++ + + A V WF+ G I
Sbjct: 1350 SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG--IAIGTDT 1407
Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA---ILTVEEPSINFTLRLPEFIL 1207
+ + L I ++DA Y+C+ N K A + + P I + + +
Sbjct: 1408 KGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESI 1467
Query: 1208 VPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
++ + + ++WY K +I+D + D KR L + K D Y
Sbjct: 1468 KESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD--KRKLHVFKAKITDSGVY 1525
Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV +A +V P +D Y+++ K G +VTL FP P W+V
Sbjct: 1526 KCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVV 1585
Query: 1324 NSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
+ +++ K K ++ + +L V G Y ++ D+++ +++L P
Sbjct: 1586 DGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPI 1645
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
N+ I++ D + + T + + E D + + + + + I +
Sbjct: 1646 VGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPS-DGHRLYITD 1704
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
K ++ ++ N + +E T V++ P E K I P I L
Sbjct: 1705 AKPENNGKYMCRVTNS---AGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNP---IILQ 1758
Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
C G P+P V W DG + + ++ C A N G
Sbjct: 1759 CQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRD 1817
Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNI 1621
IQ T NE ++ E + + ++ W K G L END I
Sbjct: 1818 FF--IQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA---I 1872
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
T + T + I R H YT A+NTAG S + + V P K + V+ EI+
Sbjct: 1873 FTLDNTR-LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP-KIKNAVVTLEIN 1928
Score = 157 bits (380), Expect = 1e-37
Identities = 244/1092 (22%), Positives = 419/1092 (38%), Gaps = 106/1092 (9%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GES 751
+ + +K G YT + N GEA + +PP + + L S ++
Sbjct: 2630 MSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN----DPPSISDELSSANIQTIVPYYP 2685
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
V ++ V G+P P + W ++KP++ A ++G+T I +V+ G YT +A
Sbjct: 2686 VEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV---RSQVEHAGTYTCEA 2742
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITW 866
+N+ G A ++ V PP F +E+ + T+ L + P+ S+ W
Sbjct: 2743 QNNVGKARKDFLVRV-------TAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYW 2795
Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ ++E + + IT + L +TN+ + D G Y C A N AG + ++ + +E
Sbjct: 2796 HAHDESVQ-NGVITSKYAANEKTLNVTNIQLD-DEGFYYCTAVNEAGITKKFFKLIV-IE 2852
Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXX 984
F+ QK Y GK + L+C + T + + + K ++ D +II
Sbjct: 2853 TPYFLDQ-QKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII----GSTL 2907
Query: 985 XXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
G CI +++ M+V P+ ++ + EV+ D LE I
Sbjct: 2908 VIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIE 2967
Query: 1042 SETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + W R + K + + KLYI + D YSCI +++ AE
Sbjct: 2968 DTSGVHITWSR--QFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEA 3025
Query: 1101 T---VVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSEIQFSNHIQL 1154
V PP+I + + T EI T+G + WF DG I +
Sbjct: 3026 VFQVTVNTPPKIFGDSFSTTEIVAD-TTLEIPCRTEGIPPPEISWFLDGKPILEMPGV-- 3082
Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
T L+I + + G Y+C + G ++ + + EP + E + V
Sbjct: 3083 TYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR--VVMASEVMRVVE 3140
Query: 1211 NTDAYLTVEI---PDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
+ E+ P+ V W K + D +F+ K L +R+ T D Y
Sbjct: 3141 GRQTTIRCEVFGNPEPV--VNWLKDGEPYTSDLLQFS----TKLSYLHLRETTLADGGTY 3194
Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
TC+ + +S T VEV+ PP+I D ER + K G+ + P P W N
Sbjct: 3195 TCIATNKAGESQTTTDVEVL-VPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN 3253
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K I+ + L I+ D G Y N G A + + + KP+
Sbjct: 3254 GK----------EIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPT-- 3301
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI------SVKNITKTQT 1438
E ++ NI G S I ++ T W+ ++ NI +
Sbjct: 3302 -----FETHETTFNIV------EGESAKIECKIDGHPKPTISWLKGGRPFNMDNIILSPR 3350
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNE 1497
L + RF V + ++ + +KV TK T+++ K +
Sbjct: 3351 G-DTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVA---GG 3406
Query: 1498 DIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+I L C G P P VTW R D ++ T N Y CIA N+
Sbjct: 3407 EIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEA 3466
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G + T + KP ++ + + D + + P P + W++ +
Sbjct: 3467 GNLTTHYAAEVIGKPTFVRKGGNLYEVIE-NDTITMDCGVTSRPLPSISWFRGDKPVYLY 3525
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
Y+I+ S I I + K S KY ASN AGTS +++ LK+ P + +I
Sbjct: 3526 DRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGN 3583
Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
++ + TI + P+ G+ K+ D N + ++ ET+ I+ + +
Sbjct: 3584 PLAIVARTIYLECPI--SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641
Query: 1737 YMFRVIAQNPVG 1748
+ A N G
Sbjct: 3642 GRYTCTATNRGG 3653
Score = 155 bits (377), Expect = 2e-37
Identities = 223/1013 (22%), Positives = 380/1013 (37%), Gaps = 81/1013 (7%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L I + K G+Y N G A+ L ++ PP ++ V + S++L
Sbjct: 2063 LHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQV----PPTIVNEGGEYTVIENNSLVL 2118
Query: 755 SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+V G P P +TW K+ +PV K++ S+G I ++ +G Y A+N
Sbjct: 2119 PCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIV---HAEIAHKGSYICMAKNDV 2175
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG---TIKLVARVTRNPVPSITWYR 868
G AE S + + P+ + I KG K +N I W R
Sbjct: 2176 GTAEISFDVDI-------ITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLR 2228
Query: 869 NNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
N + I +E + L I NV +E D G Y C N AG++S + T+ V
Sbjct: 2229 NYQPIDLEAEDARITRLSNDRRLTILNV-TENDEGQYSCRVKNDAGENSFDFKATVLVPP 2287
Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG--RXXX 983
+ K+ E TV L C + W+ + + I + +II G
Sbjct: 2288 TIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ 2347
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRK--LQDFEVKEKDVAILEV 1038
D G C + S V TIP+ + D+E ++ + ++
Sbjct: 2348 LKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC 2407
Query: 1039 EINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
+ + A + W + G KP ++ + + +KLY+ D +Y+CI +E+ T
Sbjct: 2408 PVYARPPAKITWLKAG---KPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGT 2464
Query: 1098 ----AEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147
+V+++ P P I+ R+ VN GN +T KG + W KDG+ I+
Sbjct: 2465 DKRDFKVSMLVAPSFDEPNIVRRI---TVNSGNPSTLHCP-AKGSPSPTITWLKDGNAIE 2520
Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP 1203
N + D +Q L+I + D G Y+C VG+ L V P + R
Sbjct: 2521 -PNDRYVFFDAGRQ-LQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGER-R 2577
Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDT---EKFTLISDVKKRTLIIRKCT 1259
E + V + L + +DV W K I +DT + F I K+ +
Sbjct: 2578 EAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFL-SAR 2636
Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFP 1315
+ D YTC++ + A KL V PP I D I+ V + P
Sbjct: 2637 KSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSP 2696
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
P W+ + K ++ + + +L I + + AG Y +NN G A + V
Sbjct: 2697 HPKVYWLFDDKPLEP-DSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLV 2755
Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
+ P + + + + + C E++ + +Y+ + + S
Sbjct: 2756 RVTAPPHFEKEREEVVARVGDTMLLTC--NAESSVPLSSVYWHAHDESVQNGVITSKYAA 2813
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
+ ++ N++ + + AVNE I T +++K+I I++P K
Sbjct: 2814 NEKTLNVTNIQLDDEGFYYCTAVNEAGI-----TKKFFKLI---VIETPYFLDQQKLYPI 2865
Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
+ + L C G P P + + +DGK+L + Y CIA
Sbjct: 2866 ILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAE 2925
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
N G E +V + P +S E I + + GD + IE + W + K
Sbjct: 2926 NKAGRSEKDMMVEVLLPP--KLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGK- 2982
Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ + + S + I + + Y+ A N AG + + V P
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035
Score = 155 bits (375), Expect = 4e-37
Identities = 250/1241 (20%), Positives = 449/1241 (36%), Gaps = 107/1241 (8%)
Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
+ +N A F T L + DH T D++ + P
Sbjct: 1866 LTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTL 1925
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
++EG +I+L C P P W F ++ P E + V ++ H + + NV K+
Sbjct: 1926 EINEGEEIILTCDAEGNPTPTAKWDFNQGDL-PKEAVFV---NNNH----TVVVNNVTKY 1977
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G Y A N+ G+A I + ++T + + E + V S+ L V
Sbjct: 1978 HTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTE--SELTVNLTRSITLECDVDDAIG 2035
Query: 764 PTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
I+W N KP A + T + G I K D G Y N G+A +
Sbjct: 2036 VGISWTVNGKPFLAETDGVQTLAGGRFLHIV---SAKTDDHGSYACTVTNEAGVATKTFN 2092
Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
+ V+ PP +N E TV E ++ L VT P P +TW ++ + +++
Sbjct: 2093 LFVQ-------VPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSV 2145
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT---FVKHLQK 936
+G+ ++V + G Y C+A N G A ++ DV+ +T K ++
Sbjct: 2146 QVLSEGQQFKIVHAEI---AHKGSYICMAKNDVGT----AEISFDVDIITRPMIQKGIKN 2198
Query: 937 SYETEEGKTVILECQTSHTVSTK----WYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXX 991
+G + +C + K W N + I + I +
Sbjct: 2199 IVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTE 2258
Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQD---FEVKEKDVAILEVEINSETA 1045
D G C VK+ K T+ P I +D V+ V +
Sbjct: 2259 NDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEP 2318
Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTSVHDEGEYSCILRDESCTAE---- 1099
D+ W +DGE I +N D G + +L I D G+Y+C + + + E
Sbjct: 2319 DITWFKDGEAIH-IENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVN 2377
Query: 1100 VTVVELPPEIITRLQNQKVNKGN-KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157
V V+ +P + + ++ N + + + A + W K G +Q ++ + +
Sbjct: 2378 VNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSAN 2437
Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCT-AILTVEEPSINFTLRLPEFILVPANT 1212
G QKL ++ D+ +Y+C E G K + + PS + + + N
Sbjct: 2438 G--QKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNP 2495
Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
+ +TW K + IE +++ R L I K DQ YTC+ +
Sbjct: 2496 STLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFD--AGRQLQISKTEGSDQGRYTCIATN 2553
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
+ + L+ + P ++D ER + G L D + + EW + I +
Sbjct: 2554 SVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFCDSNS-TGVDVEWQKDGLTINQ 2612
Query: 1331 CKHTKPS---IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
S I S ++ +D+G Y + N G A + + D PS
Sbjct: 2613 DTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS----- 2667
Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN- 1446
+ + SS NI P I VV W+ + ++ L N
Sbjct: 2668 --ISDELSSANIQTIVPY---YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNG 2722
Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTC 1503
+ + V K K+ ++ P EK + + + + LTC
Sbjct: 2723 ETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTC 2782
Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
VP V W+ + ++ T + N Y C A N+ G
Sbjct: 2783 NAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGIT 2842
Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
+ + + + P ++ +G + G PPP +++ K+G +L E
Sbjct: 2843 KKFFKLIVIETPYFL--DQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEV 2900
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
+I S + I ++ +YT A N AG S ++ ++V P + + + +
Sbjct: 2901 DII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQA 2956
Query: 1680 RESVTIEWKPPLDDGGLELT---KYAIE-------KHEPDNNRWIKVADVDRDVETYCIQ 1729
+ +T+E P D G+ +T ++ + + D ++ + D ++Y
Sbjct: 2957 GDPLTLEC-PIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCI 3015
Query: 1730 KLNE--NCEYMFRVIAQNPVG-FSEALESEPIVIKTALDVP 1767
+N+ E +F+V P F ++ + IV T L++P
Sbjct: 3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIP 3056
Score = 154 bits (374), Expect = 6e-37
Identities = 197/794 (24%), Positives = 327/794 (41%), Gaps = 74/794 (9%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A++ G PT + P V+ + L+C V IP P+I W KG ++ N +
Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQ 843
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
+ L IT+ + +G +T +A N G+ S L + TG P P + +
Sbjct: 844 ----LADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMV-TGLVSPVLGHVPPEEQL 898
Query: 746 VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
+ +G+ + LS VV G P+P+I W K++KPV+ PT S+ L+ KDEG YT
Sbjct: 899 I-EGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYT 957
Query: 805 LKAENSEG----------IAETSAVITVE-----EPTEENAEPP--LFINRFQEITVKEK 847
A + G I + V E +PT + +N ++ E
Sbjct: 958 CIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEG 1017
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKC 906
I V V+ P P ITWY + I+P S T D L++ D SG Y C
Sbjct: 1018 FAIPCV--VSGTPPPIITWYLDGRPITPNSRDFTVTADN---TLIVRKADKSY-SGVYTC 1071
Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHN 963
A+NSAG + + TI + + Q S+ + C V T +
Sbjct: 1072 QATNSAGDNEQ--KTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDD 1129
Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020
K G+ + ++G G C ++ +T T+ + T P
Sbjct: 1130 KPFTEGV----VNEDGSLTIPNVNEAHR---GTFTCHAQNAAGNDTRTVTLTVHTTPTIN 1182
Query: 1021 RKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ Q+ + D +LE + V +W +GE I + + + G L ++N
Sbjct: 1183 AENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG---ALVLQNV 1239
Query: 1080 SVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD 1134
+ + G + C + ++S + +TV E P+II+ + V KG T
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHE-KPKIISEVPGVVDVVKGFTIEIPCRATGVP 1298
Query: 1135 ALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAIL 1189
++R W K+G +++ + ++D L+IY+ D +D G Y+C E G S+ T +
Sbjct: 1299 EVIRTWNKNGIDLKMDEK-KFSVD-NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHV 1356
Query: 1190 TVEEPSINF-TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTLISD 1247
V+EP I + + +V + VE VTW+++ I DT+ + + SD
Sbjct: 1357 DVQEPPIILPSTQTNNTAVVGDRVELKCYVE-ASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSD 1304
TL+I+ + +D YTC + K+ L+V V+ P K D + IK
Sbjct: 1416 ---GTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
+L + P P W +N K + K + + D K L + K + TD+G+YK N
Sbjct: 1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDK-RKLHVFKAKITDSGVYKCVARN 1531
Query: 1365 NCGHADVEMNVTIL 1378
G V ++
Sbjct: 1532 AAGEGSKSFQVEVI 1545
Score = 153 bits (372), Expect = 1e-36
Identities = 255/1182 (21%), Positives = 445/1182 (37%), Gaps = 104/1182 (8%)
Query: 523 DGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C V G P+P I W + KP ++ + + L +R P+D G +
Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWIKDD---KPVEEGPTIKIEGGGSLLRLRGGNPKDEGKY 956
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
TC+A + AG +ST + V+ E + + E +
Sbjct: 957 TCIAVSPAG--NSTLHINVQLIKKP---EFVYKPEGGIVFKPTISGMDEKHVAVVNS--- 1008
Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
V +G + C + P P I W G I P+ + +D + L +
Sbjct: 1009 THDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSR-DFTVTAD-----NTLIVRKAD 1062
Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
K G YT A N G+ ++I P + S + + + V G+
Sbjct: 1063 KSYSGVYTCQATNSAGDNEQKTTIRI----MNTPMISPGQSSFNMVVDDLFTIPCDVYGD 1118
Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
P+P ITW ++KP DG S+TI + G +T A+N+ G + +T
Sbjct: 1119 PKPVITWLLDDKPFTEGVVNEDG---SLTIPNVNEA-HRGTFTCHAQNAAGNDTRTVTLT 1174
Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
V NAE QE + I L P P W E I S+ I
Sbjct: 1175 VHTTPTINAEN-------QEKIALQNDDIVLECPAKALPPPVRLWTYEGEKID-SQLIPH 1226
Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
E+ LV+ NV E ++G + C SN AG+ S +T+ EK + + +
Sbjct: 1227 TI-REDGALVLQNVKLE-NTGVFVCQVSNLAGEDSLSYTLTVH-EKPKIISEVPGVVDVV 1283
Query: 942 EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
+G T+ + C+ + V W N ++ MD ++ + D+G C
Sbjct: 1284 KGFTIEIPCRATGVPEVIRTWNKNGIDLK-MDEKKFSVD-NLGTLRIYEADKNDIGNYNC 1341
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-----SETADVVWERDGE 1054
+V ++ ++ + + E L + V VE+ S A V W R G
Sbjct: 1342 VVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGI 1401
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP---- 1106
I Y E G L I++ SV D Y+C + + AE VTV+ P
Sbjct: 1402 AIGTDTKGYVVESDG---TLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKD 1458
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+++T+ + + + + + + + W+ + + T D K+ KL +
Sbjct: 1459 PDVVTQ---ESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKR-KLHV 1514
Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF-ILVPANTDAYLTVEIPDE 1223
+ + D+G Y C N+ + + E + L ++ V A +T+ P
Sbjct: 1515 FKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS 1574
Query: 1224 TL---DVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
+ W +V+E +K+ TL +D TL + + Y CV +
Sbjct: 1575 GFPVPQINWVVDGTVVEPGKKYKGATLSND--GLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632
Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTK 1335
+ VE+ IV + + G D++L D Q W +N + + +
Sbjct: 1633 DIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQ 1692
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEI 1392
D +T K EN G Y R+ N+ G A+ + + +L+ P P + N I
Sbjct: 1693 IPSDGHRLYITDAKPENN--GKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLI 1750
Query: 1393 DSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
++ I + + + TGN + + ++ ++D + W+ ++++ + I+ L T S +
Sbjct: 1751 GNNPIIL---QCQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLR--IEKL-TGKSAQI 1803
Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT-EPNEDIELTCIFGGVPQ 1510
A N+ + + +++ I +PT + T +E I L C +
Sbjct: 1804 SCTAENKA----GTASRDFF----IQNIAAPTFKNEGDQETIFRESETITLDCPV-SLGD 1854
Query: 1511 PKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
++TW + G L A + + Y C+A N G+V V +Q
Sbjct: 1855 FQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQV 1914
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
P I N + + G+E ++T EG P P W N L KE T V
Sbjct: 1915 LP--KIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDFNQGDL--PKEAVFVNNNHTVV 1970
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
+ + + H+ Y A+N G + + + V KP G
Sbjct: 1971 --VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESG 2010
Score = 145 bits (351), Expect = 3e-34
Identities = 245/1099 (22%), Positives = 431/1099 (39%), Gaps = 110/1099 (10%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+PP SK+ V G + LEC + I W + D + + +S
Sbjct: 2941 LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW---SRQFGKDGQLDMRAQSSSDK- 2996
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGE 750
S L I +Y+ +AVN G A + + T PP++ + + +
Sbjct: 2997 -SKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADT 3051
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTH-SITILKPKKVKDEGVYTLKA 807
++ + + G P P I+W + KP+ +P T GD I +KP + EG YT A
Sbjct: 3052 TLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQ---EGRYTCVA 3108
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
EN G AE + + +EPP + + + V E + V NP P + W
Sbjct: 3109 ENKAGRAEQDTYVEI-------SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWL 3161
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
++ E + S+ + + + L T + D G Y C+A+N AG+S + T DVE
Sbjct: 3162 KDGEPYT-SDLLQFSTKLSYLHLRETTL---ADGGTYTCIATNKAGES----QTTTDVEV 3213
Query: 928 VT--FVKHLQKSYETEEGKTVILECQ-TSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX 983
+ ++ ++ + +EG T ++ CQ T V W N KEI + I+
Sbjct: 3214 LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIRNA---- 3269
Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
D G CI ++ + + L+ T P F F + E + A +E +I
Sbjct: 3270 ------TRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKI 3323
Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
+ + W + G + RG L I D G Y+C+ + +E
Sbjct: 3324 DGHPKPTISWLKGGRPFN--MDNIILSPRGDT--LMILKAQRFDGGLYTCVATNSYGDSE 3379
Query: 1100 ----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLT 1155
V V P T Q K G + + + +K G + N + T
Sbjct: 3380 QDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDA-VPNDSRHT 3438
Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210
I LKI +DAG+YSC E GN + A + +P+ F + V
Sbjct: 3439 IVNNYD-LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPT--FVRKGGNLYEVIE 3495
Query: 1211 NTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
N + + L ++W++ + +++++ D T I K D +Y C
Sbjct: 3496 NDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHIT--INKAKLSDGGKYICR 3553
Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY-----QAFPQPNDEWIV 1323
+ T+ + + + + PPKI ++ I + Y PQP+ W
Sbjct: 3554 ASNEAGTSDIDLILKILVPPKI---DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK 3610
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS- 1382
N I ++ + + + I+ V+ TD G Y N G A + ++ +L P
Sbjct: 3611 NGMDINMTD-SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEF 3669
Query: 1383 --PPGKPNIL-EIDSSSINICWDEPENTGNSTI-IYYVVEYQEID--TTEWISVKNITKT 1436
+P I E D+ ++ E+ + + + + + + +D T+ + + + +
Sbjct: 3670 DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRK 3729
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP- 1495
T Q N+ + A+N A E + +KV +I SP V +N +P
Sbjct: 3730 LTISQASLENAGL-YTCIALNR-----AGEASLEFKV----EILSPPVIDISRN-DVQPQ 3778
Query: 1496 ---NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKC 1550
N+ + C G P P + W ++GK++ + E + C
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 3838
Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
+A ND G E V+ + PV+++ +++ IK +G+ + G P P++ W K
Sbjct: 3839 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA---LGETITLFCNASGNPYPQLKWAKG 3895
Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
G+ L D K + + I LK++ YT +A N AGTS V++ V P
Sbjct: 3896 GS-LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEIN 3954
Query: 1670 EGPVIM--REISRESVTIE 1686
+ M R +++S+T++
Sbjct: 3955 RDGIDMSPRLPAQQSLTLQ 3973
Score = 141 bits (341), Expect = 6e-33
Identities = 241/1190 (20%), Positives = 427/1190 (35%), Gaps = 123/1190 (10%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLV 569
I ++K + K + STV C G P P ITWF+ I + + + N L
Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
I + DAG +TC A N+AG + ++ P +
Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEK--------------------- 2388
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+GIP + + + +++ C + A P I WL G+ + D+ + + +
Sbjct: 2389 -DGIPSDYESQ-------QNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS-ANGQ 2439
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747
+Y L+ T+ K YT +A N G + + + P ++ + + V
Sbjct: 2440 KLYLFKLRETDSSK-----YTCIATNEAGTDKRDFKVSMLVAPSFDEPNIV---RRITVN 2491
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
G L G+P PTITW K+ ++ D + + D+G YT A
Sbjct: 2492 SGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIA 2551
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
NS G + + V P P + R + + V E + +L V + W
Sbjct: 2552 TNSVGSDDLENTLEVIIP------PVIDGERREAVAVIEGFSSELFCDSNSTGV-DVEWQ 2604
Query: 868 RNNEIISPSETITQNF-----DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
++ I+ +F G+ + + + DSG Y C+ N AG+ AR
Sbjct: 2605 KDGLTINQDTLRGDSFIQIPSSGKKMSFLSAR---KSDSGRYTCIVRNPAGE----ARKL 2657
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVI------LECQTSHTVSTK--WYHNKKEISGMDHRE 974
D V + + +T++ + C S + K W + K + D
Sbjct: 2658 FDF-AVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLE-PDSAA 2715
Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEK 1031
G C ++ + LV P F ++ ++ +
Sbjct: 2716 YELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVG 2775
Query: 1032 DVAILEVEINSET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
D +L S + V W E + + + + + L + N + DEG Y C
Sbjct: 2776 DTMLLTCNAESSVPLSSVYWHAHDESV--QNGVITSKYAANEKTLNVTNIQLDDEGFYYC 2833
Query: 1090 ILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
+E+ ++ V+E P + + + + G + T + T + + KDG
Sbjct: 2834 TAVNEAGITKKFFKLIVIE-TPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204
+ S+ + + L I + + G Y+C N + + + E
Sbjct: 2893 RLNESDEVDII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948
Query: 1205 FILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
+I V LT+E P E + +TW ++ + S K + L I + T +
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK-LYIMQATPE 3007
Query: 1262 DQCEYTCVLL-DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPND 1319
D Y+C+ + DA + V PPKI D I + + + + P P
Sbjct: 3008 DADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEI 3067
Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W ++ K I + P + K SL I ++ G Y EN G A+ + V I
Sbjct: 3068 SWFLDGKPILE----MPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEI 3123
Query: 1378 LDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
+ P ++ ++ I E GN + ++ E T++ + T
Sbjct: 3124 SEPPRVVMASEVMRVVEGRQTTI---RCEVFGNPEPVVNWLKDGEPYTSDLLQF----ST 3176
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
+ S +L+ + Y + + S+TT +V + P +E + + +
Sbjct: 3177 KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV-----LVPPRIEDEERVLQGKEG 3231
Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+ C G P P VTW R+GK+++ R Y CIA N+
Sbjct: 3232 NTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIR------NATRADEGKYSCIASNEA 3285
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
G ++ + KP T + G+ + I+G P P + W K G D
Sbjct: 3286 GTAVADFLIDVFTKP--TFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMD 3343
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
NI + + I + +R YT A+N+ G S + + VY KP
Sbjct: 3344 ---NIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390
Score = 138 bits (335), Expect = 3e-32
Identities = 248/1116 (22%), Positives = 432/1116 (38%), Gaps = 104/1116 (9%)
Query: 599 IVEAPLSDHGSEMT-VXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLEC 655
I +A ++G M V D+LE PP F + Q + + I+L+C
Sbjct: 1702 ITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE--PPVFVEPVFEANQKLIGNNPIILQC 1759
Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
++ P+P + W G ++ + S + + S+L+I + + + A N+
Sbjct: 1760 QVTGNPKPTVIWKIDGNDV----DKSWLFDESL----SLLRIEKLTG-KSAQISCTAENK 1810
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKP 774
G AS ++ P E + I R+ E++ L V +G+ + ITW K P
Sbjct: 1811 AGTASRDFFIQ---NIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ--ITWMKQGLP 1865
Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPP 833
+ D +TIL + E +YT A N+ G +++ V+ P +NA
Sbjct: 1866 LTENDAIFTLDNTRLTILNANR-DHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVT 1924
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
L IN +EI L NP P+ W N + P E + F N +V+
Sbjct: 1925 LEINEGEEII--------LTCDAEGNPTPTAKWDFNQGDL-PKEAV---FVNNNHTVVVN 1972
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVILECQT 952
NV ++ +G YKC A+N G++ V + K F L +S T +++ LEC
Sbjct: 1973 NV-TKYHTGVYKCYATNKVGQAVKTINVHVRT-KPRFESGLTESELTVNLTRSITLECDV 2030
Query: 953 SHT--VSTKWYHNKKE-ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ET 1006
V W N K ++ D + + GR D G C V ++ T
Sbjct: 2031 DDAIGVGISWTVNGKPFLAETDGVQTLAGGR--FLHIVSAKTDDHGSYACTVTNEAGVAT 2088
Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065
T + + P + + ++ V E + +L E+ + VV W +DG +P +
Sbjct: 2089 KTFNLFVQVPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG---RPVGDLKSV 2145
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK-------V 1118
+ ++ I + + +G Y C+ +++ TAE++ +IITR QK
Sbjct: 2146 QVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEIS---FDVDIITRPMIQKGIKNIVTA 2202
Query: 1119 NKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDLDDAG 1174
KG F+ + + W ++ I + ++T ++L I + +D G
Sbjct: 2203 IKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEG 2262
Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETL------- 1225
+YSC V N E S +F T+ +P I++ VE TL
Sbjct: 2263 QYSCRVKND-------AGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGK 2315
Query: 1226 ---DVTWYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-- 1278
D+TW+K IE+ ++ L I + E D +YTC ++ + +
Sbjct: 2316 PEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQD 2375
Query: 1279 LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
+ V V+ P D +Y ++ V + A P W+ K ++ K K S
Sbjct: 2376 VNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS 2435
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSS 1396
+ + L + K+ TD+ Y N G + V++L PS +PNI+ I +S
Sbjct: 2436 ANGQ--KLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPS-FDEPNIVRRITVNS 2492
Query: 1397 IN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
N P S I ++ + I+ + + + Q I + + R+ A
Sbjct: 2493 GNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGR-QLQISKTEGSDQGRYTCIA 2551
Query: 1456 VNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
N V D T E VI + ++ V ++ ++E D T + + +
Sbjct: 2552 TNSVGSDDLENTLEVIIPPVIDGERREAVAV---IEGFSSELFCDSNSTGVDVEWQKDGL 2608
Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
T +D + + + Y CI N GE + P I
Sbjct: 2609 TINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSI 2668
Query: 1574 T--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVI 1630
+ +S+ +I Q + V+ G P P+V W + LE D Y +T +T +
Sbjct: 2669 SDELSSANI-QTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET--L 2725
Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+I + H+ YT EA N G + + ++V P
Sbjct: 2726 KIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPP 2761
Score = 132 bits (319), Expect = 3e-30
Identities = 240/1100 (21%), Positives = 415/1100 (37%), Gaps = 121/1100 (11%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
DI+E PP+ P+ Y + + L C + P+P++ W FKG ++ D V +S
Sbjct: 606 DIME--PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDS 663
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
L I + EGTY A+++ G+A L + T PP+V M+V
Sbjct: 664 ------KFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLAT----PPKVEIIQNKMMV 713
Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
+G+ V + + G P P I W KN K + + + I+ K +D G Y+
Sbjct: 714 GRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKD-EDAGAYSC 772
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
EN G A ++V P I + V + + L P P I
Sbjct: 773 VGENMAGKDVQVANLSV-------GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIE 825
Query: 866 WYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W + N +++ + TQ DG L+IT+ E D G + C+A N+ G+ S + +
Sbjct: 826 WQKGNVLLATLNNPRYTQLADG---NLLITDAQIE-DQGQFTCIARNTYGQQSQSTTLMV 881
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGR 980
+ H+ + EG+ + L C + S W + K + + I EG
Sbjct: 882 TGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVE--EGPTIKIEGG 939
Query: 981 XXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD---FE-----VK 1029
D G CI V ST+ + + I PEF+ K + F+ +
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 1030 EKDVAILE---------------VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
EK VA++ V + + W DG I P N DF L
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITP--NSRDFTVTAD-NTL 1056
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132
+R G Y+C + + E T + + + N F I
Sbjct: 1057 IVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVY 1116
Query: 1133 GD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCT 1186
GD ++ W D + F+ + + DG L I + + G ++C GN T
Sbjct: 1117 GDPKPVITWLLD--DKPFTEGV-VNEDG---SLTIPNVNEAHRGTFTCHAQNAAGNDTRT 1170
Query: 1187 AILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV---TW-YKKKSVIEDTEK 1241
LTV P+IN E I + N D + +E P + L W Y+ + +
Sbjct: 1171 VTLTVHTTPTIN--AENQEKIAL-QNDD--IVLECPAKALPPPVRLWTYEGEKIDSQLIP 1225
Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
T+ D L+++ ++ + C + L + + + V E P I + +
Sbjct: 1226 HTIRED---GALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
+G + + P+ W N I K K S+D+ +L I + + D G Y
Sbjct: 1283 VKGFTIEIPCRATGVPEVIRTWNKNG-IDLKMDEKKFSVDN-LGTLRIYEADKNDIGNYN 1340
Query: 1360 LRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYV 1416
+ N G + + +V + + P P + N + + + C+ E + T
Sbjct: 1341 CVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG 1400
Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
+ DT ++ + T IQ+ + + A N ++A+ ++
Sbjct: 1401 IAI-GTDTKGYVVESDGTLV---IQSASVEDATIYTCKASNPAGKAEAN--------LQV 1448
Query: 1477 TKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYEN 1531
T I SP ++ P + + + + L C P P+++WY + K L KT+ T ++
Sbjct: 1449 TVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD 1508
Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----G 1587
+ YKC+A N GE S Q + ++ ++ ++ K K KV G
Sbjct: 1509 KRKLHVFKAKITDSGVYKCVARNAAGEGSKS----FQVEVIVPLNLDESKYKKKVFAKEG 1564
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
+E + + G P P++ W +G +E K+Y T + + + Y
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCV 1624
Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666
A + ++V L V P
Sbjct: 1625 AQSKGNILDIDVELSVLAVP 1644
Score = 125 bits (302), Expect = 3e-28
Identities = 172/797 (21%), Positives = 313/797 (39%), Gaps = 68/797 (8%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
I T + PKA G +I+L+C ++ P P + W +G++ VP+++ + +
Sbjct: 3392 IDETIDQTPKAV---AGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN----- 3442
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
LKI +V G Y+ +AVN G + ++ G+ P V + V + ++
Sbjct: 3443 -YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEV-IGK--PTFVRKGGNLYEVIENDT 3498
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+ + V P P+I+W + +KPV S S + K+ D G Y +A N
Sbjct: 3499 ITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEA 3558
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
G ++ ++ + P + + I I + TI L ++ P P + W +N
Sbjct: 3559 GTSDIDLILKILVPPK--IDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGM 3613
Query: 872 IISPSET---ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
I+ +++ + QN + IE V D G Y C A+N GK+SH + + +
Sbjct: 3614 DINMTDSRVILAQNNETFGIENV-----QVTDQGRYTCTATNRGGKASHDFSLDV-LSPP 3667
Query: 929 TFVKHLQKSYETEEGKTVILECQ-------TSHTVSTKWYHNKKEISG--MDHREIIQEG 979
F H + EG T+ L C + W + + + G D+ +I +G
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVA 1034
R + G+ CI ++ E S V+ P I R +V
Sbjct: 3728 R--KLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPT 3785
Query: 1035 ILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
I+ + + W ++G+ + +N ++G + ++ +R S H G++SC+ +
Sbjct: 3786 IMRCAVTGHPFPSIKWLKNGKEVTDDEN-IRIVEQGQVLQI-LRTDSDH-AGKWSCVAEN 3842
Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS 1149
++ E+ + V PP + + N G T + ++W K GS I F
Sbjct: 3843 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLI-FD 3901
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPE 1204
+ I K +L I D G+Y+C+ N+ T+ +V P IN +
Sbjct: 3902 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD-GIDM 3960
Query: 1205 FILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
+PA L + + + W ++ T T+ SD + I + D
Sbjct: 3961 SPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASD--STFIQINNVSLSD 4018
Query: 1263 QCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
+ YTC + + L V+VV+ P ++ ++ G + + +P P
Sbjct: 4019 KGVYTCYAENVAGSDNLMYNVDVVQAP--VISNGGTKQVIEGELAVIECLVEGYPAPQVS 4076
Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
W+ N ++ + + LTI + + D+GIY N G A + +L
Sbjct: 4077 WLRNGNRVETGVQGVRYV-TDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 4135
Query: 1381 PS-PPGKPNILEIDSSS 1396
P P +L S S
Sbjct: 4136 PKIITSTPGVLTPSSGS 4152
Score = 118 bits (285), Expect = 3e-26
Identities = 204/945 (21%), Positives = 362/945 (38%), Gaps = 86/945 (9%)
Query: 651 ILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
I LEC + IP+PD+ W G +I + D + +A ++ I NV+ +G YT
Sbjct: 3592 IYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNE------TFGIENVQVTDQGRYT 3645
Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILS-----AQVVGNPR 763
A NR G+AS L + + PP+ I + I R+G+++ L+ A+ + +
Sbjct: 3646 CTATNRGGKASHDFSLDVLS----PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701
Query: 764 PTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++W K+++ + T + D +TI + +++ G+YT A N G A +
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQAS-LENAGLYTCIALNRAGEASLEFKV 3760
Query: 821 TVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
+ P P + I+R Q + TI A VT +P PSI W +N + ++ E
Sbjct: 3761 EILSP------PVIDISRNDVQPQVAVNQPTIMRCA-VTGHPFPSIKWLKNGKEVTDDEN 3813
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
I G+ ++++ T+ D +G + CVA N AG + +DV V +
Sbjct: 3814 IRIVEQGQVLQILRTDSDH---AGKWSCVAENDAGVKE--LEMVLDVFTPPVVSVKSDNP 3868
Query: 939 ETEEGKTVILECQTSHTV--STKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVG 995
G+T+ L C S KW I D I +G DVG
Sbjct: 3869 IKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKG--ARLDIPHLKKTDVG 3926
Query: 996 VIKC-IVKDQETSTMLVVKETI--PEFIRKLQDFEVK---EKDVAILEVEINSETADVVW 1049
C + TS V + + PE R D + ++ + + + + W
Sbjct: 3927 DYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRW 3986
Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL 1105
+G + + I N S+ D+G Y+C + ++ V VV+
Sbjct: 3987 TLNGTALTHSTPGITVASDSTF--IQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQA 4044
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS-NHIQLTIDGKKQKL 1163
P +I+ ++V +G A E + A V W ++G+ ++ ++ DG+ L
Sbjct: 4045 P--VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM--L 4100
Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAY-LTVEI 1220
I + D+G Y C N +A T+E + +L P++ + L +
Sbjct: 4101 TIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV 4160
Query: 1221 ---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
PD ++W + I+D E I TL I K E+ Y C +
Sbjct: 4161 RGYPDPI--ISWTLNGNDIKDGENGHTIG--ADGTLHIEKA-EERHLIYECTAKNDAGAD 4215
Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
T + V+ + P R G++ + + ++ W N + +
Sbjct: 4216 TLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLI 4274
Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
S D K + ++ +D G Y N G+A + N+ + P +P +
Sbjct: 4275 FSEDYKLIKILSTRL--SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG 4332
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAY 1454
W E I +Y + E+ T + TK ++ I ++ + + +
Sbjct: 4333 DQVTLWCEASGVPQPAITWY--KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCK 4390
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
A N V + E + +I P V N++T P + + L+C G+P+P ++
Sbjct: 4391 AENWV--ASTEEDIDLIVMIP------PEVVPERMNVSTNPRQTVFLSCNATGIPEPVIS 4442
Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGE 1558
W RD Y+ Y CIA +D G+
Sbjct: 4443 WMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ 4487
Score = 115 bits (277), Expect = 3e-25
Identities = 167/808 (20%), Positives = 317/808 (39%), Gaps = 71/808 (8%)
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957
D+G+Y+C ++ G S RV ++ G+ L C T V
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFG--VRNVSVPLGEAAFLHCSTRSAGEVE 550
Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKE 1014
+W + + E + D GV +C+ ++ T M +
Sbjct: 551 IRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608
Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
P QD ++ L E + +V W G + N Y ++ +
Sbjct: 609 EPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLL---NDYKYQVGQDSKF 665
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIEL 1130
LYIR+ + HDEG Y C ++ A T ++ PP++ V +G++ +FE +
Sbjct: 666 LYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKT 725
Query: 1131 TKGDA--LVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
+G +RWFK+G + I+ ++I++ + +L I +DAG YSC VG +
Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKIN----EGQLHIMGAKDEDAGAYSC-VGENMAGK 780
Query: 1188 ILTVEEPSINFTLRLPEFILVP----ANTDAYLTVE---IPDETLDVTWYKKKSVIE--D 1238
+ V S+ R+P I P N + +T++ + ++ W K ++ +
Sbjct: 781 DVQVANLSVG---RVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLN 837
Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIVDY 1293
++T ++D L+I +DQ ++TC+ + ++STT + +V P +
Sbjct: 838 NPRYTQLAD---GNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS--PVLGHV 892
Query: 1294 EREYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
E ++ G D+TL V P+P+ WI + K +++ K I+ + L ++
Sbjct: 893 PPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIK--IEGGGSLLRLRGGNP 950
Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKP----SPPG----KPNILEIDSSSINICWDEP 1404
D G Y + G++ + +NV ++ KP P G KP I +D + +
Sbjct: 951 KDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTH 1010
Query: 1405 E-NTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRA---YA-VNE 1458
+ G I VV W + + IT N+ +A Y+ V
Sbjct: 1011 DVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYT 1070
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
++++ E I+ + +P + + ++ + C G P+P +TW D
Sbjct: 1071 CQATNSAGDNEQKTTIR--IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128
Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
K + + C A N G + + + P I N+
Sbjct: 1129 DKPF--TEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
+ + D+ ++ + +PPP +W G K+ D + T + + ++ +K
Sbjct: 1187 E--KIALQNDDIVLECPAKALPPPVRLWTYEGEKI--DSQLIPHTIREDGALVLQNVKLE 1242
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ + + SN AG S+ TL V++KP
Sbjct: 1243 NTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270
Score = 104 bits (250), Expect = 6e-22
Identities = 120/542 (22%), Positives = 223/542 (41%), Gaps = 36/542 (6%)
Query: 1227 VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
+TWY + + ++ FT+ +D TLI+RK + YTC ++ + K + +
Sbjct: 1032 ITWYLDGRPITPNSRDFTVTAD---NTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088
Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
P I + + + T+ D P+P W+++ K + + ++ S
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTE------GVVNEDGS 1142
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
LTI V G + +N G+ + +T+ P+ + N +I + +I + P
Sbjct: 1143 LTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE-NQEKIALQNDDIVLECP 1201
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDI 1461
+ + E ++ID+ + I +QN+K ++ F N E +
Sbjct: 1202 AKALPPPVRLWTYEGEKIDS-QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL 1260
Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
S E K+I E P V +K T IE+ C GVP+ TW ++G
Sbjct: 1261 SYTLTVHEKPKIISEV----PGVVDVVKGFT------IEIPCRATGVPEVIRTWNKNGID 1310
Query: 1522 LKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
LK K + +N Y C+ N+ G + + V +Q+ P+I S +
Sbjct: 1311 LKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQT 1370
Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
VGD + +E PP V W++ G + D + + + T VI+ ++
Sbjct: 1371 -NNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE--D 1427
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-EL 1698
++ YT +ASN AG + + + V P + V+ +E +ES P+ L ++
Sbjct: 1428 ATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQI 1487
Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP 1757
+ Y +K D+ K +D R + + K +++ +A+N G S++ + E
Sbjct: 1488 SWYLNDKPLIDDKTSWKTSDDKRKLHVF---KAKITDSGVYKCVARNAAGEGSKSFQVEV 1544
Query: 1758 IV 1759
IV
Sbjct: 1545 IV 1546
Score = 86.2 bits (204), Expect = 2e-16
Identities = 119/600 (19%), Positives = 229/600 (38%), Gaps = 57/600 (9%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++ G P F ++V G D+ L C + + I W+ GE+I+ ++
Sbjct: 425 VIVGGPRAFMSPIHQEFV--GRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDT- 481
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
SV I + G Y ++ G S+ K + +E P I ++++ V
Sbjct: 482 -----SVWTIPELSLKDAGEYECRVISNNGNYSV----KTRVETRESPPEIFGVRNVSVP 532
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
GE+ L I W + V P T+ + D GVY A
Sbjct: 533 LGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMA 592
Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
N+ G++ + + EP P Q++ + + L +P P + WY
Sbjct: 593 RNAGGMSTRKMRLDIMEPPSVKVTP-------QDVYFNMREGVNLSCEAMGDPKPEVHWY 645
Query: 868 -RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
+ +++ + G++ + + + D G Y+C A + AG+ AR T D+
Sbjct: 646 FKGRHLLNDYKYQV----GQDSKFLYIRDATHHDEGTYECRAMSQAGQ----ARDTTDLM 697
Query: 927 KVT--FVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRX 981
T V+ +Q G V EC+T +W+ N K++ D I EG+
Sbjct: 698 LATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ- 756
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKLQDFEVK-EKDVAILE 1037
D G C+ ++ + V + +P I V E+ V +
Sbjct: 757 --LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQC 814
Query: 1038 VEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093
+ + ++ W++ ++ N +Y G+ L I + + D+G+++CI R+
Sbjct: 815 LAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGN---LLITDAQIEDQGQFTCIARNTYG 871
Query: 1094 -ESCTAEVTVVELPPEIITRL-QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149
+S + + V L ++ + +++ +G T + G + W KD ++
Sbjct: 872 QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG 931
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
I+ I+G L++ + D G+Y+C + + L + I + PEF+ P
Sbjct: 932 PTIK--IEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLI----KKPEFVYKP 985
Score = 85.8 bits (203), Expect = 3e-16
Identities = 108/505 (21%), Positives = 186/505 (36%), Gaps = 47/505 (9%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V EG ++EC + P P ++WL G + V +D M L I +
Sbjct: 4055 VIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM----LTIIEARSLD 4109
Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESVILSAQVVGNPR 763
G Y A N G A L++ P++I ++ G L V G P
Sbjct: 4110 SGIYLCSATNEAGSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPD 4165
Query: 764 PTITWCKNNKPVKALPTKSDGDT-HSI----TILKPKKVKDEGVYTLKAENSEGIAETSA 818
P I+W N +K DG+ H+I T+ K + +Y A+N G
Sbjct: 4166 PIISWTLNGNDIK------DGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGAD---- 4215
Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
T+E P + P + + + I E GT ++ + +W +N + PS
Sbjct: 4216 --TLEFPVQTIVAPKISTSGNRYINGSE-GTETVIKCEIESESSEFSWSKNGVPLLPSNN 4272
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
+ + D + I+++ T + D G+Y C A+N AG ++ + ++V + ++
Sbjct: 4273 LIFSEDYKLIKILSTRLS---DQGEYSCTAANKAGNATQ--KTNLNVGVAPKIMERPRTQ 4327
Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
+G V L C+ S + WY + + ++ E + GV
Sbjct: 4328 VVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT-KKKSVIFSSISPSQAGV 4386
Query: 997 IKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD 1052
C ++ ST + ++ PE + + + + L V+ W RD
Sbjct: 4387 YTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRD 4446
Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEI 1109
I KY L IRN D+G Y CI + ++ T +V P +
Sbjct: 4447 SNIAIQNNEKYQILG----TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGD 1134
+ + KG E + +GD
Sbjct: 4503 PAPIWVECDEKGKPKKTEYMIDRGD 4527
Score = 75.8 bits (178), Expect = 3e-13
Identities = 109/530 (20%), Positives = 199/530 (37%), Gaps = 41/530 (7%)
Query: 1165 IYDCDLDDAGEYSCEV----GN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
I + L DAGEY C V GN S T + T E P F +R + VP A+L
Sbjct: 486 IPELSLKDAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCS 542
Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276
+++ W + + + + + TL I T D Y C+ +A ST
Sbjct: 543 TRSAGEVEIRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMST 600
Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
K++++++E PP + ++ V L + P+P W + + K
Sbjct: 601 RKMRLDIME-PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHL--LNDYKY 657
Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
+ S L I+ + D G Y+ R + G A ++ + P N + +
Sbjct: 658 QVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGD 717
Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
++ + I ++ I ++I I + Q I K + +
Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIK---INEGQLHIMGAKDEDAGAYSCVG 774
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
N + +V + + PT+ + + + L C+ G+P P++ W
Sbjct: 775 ENMAG--------KDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW 826
Query: 1516 YRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQ 1569
+ L T + T + CIA N +G+ T V G+
Sbjct: 827 QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS 886
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
+ + E+ Q + D L V+ G P P ++W K+ +E I + S+
Sbjct: 887 PVLGHVPPEE--QLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGP--TIKIEGGGSL 942
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMR 1676
+R++ KYT A + AG S++ + +++ KP KPEG ++ +
Sbjct: 943 LRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFK 992
Score = 66.1 bits (154), Expect = 3e-10
Identities = 55/236 (23%), Positives = 101/236 (42%), Gaps = 19/236 (8%)
Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
I+ LSD G E + ++ G+ P ++P+ Q V +G + L C
Sbjct: 4284 ILSTRLSDQG-EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 4342
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--RE 716
+P+P I W +K E++ + + E+ SV+ +++ Q G YT A N
Sbjct: 4343 GVPQPAITW-YKDNELLTNTGVD---ETATTKKKSVI-FSSISPSQAGVYTCKAENWVAS 4397
Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
E + +++ I PP+V+ ++ ++V LS G P P I+W +++
Sbjct: 4398 TEEDIDLIVMI------PPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAI 4451
Query: 777 ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
K G T +I + P D+G Y A++ G + + V +P++ A
Sbjct: 4452 QNNEKYQILGTTLAIRNVLP---DDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPA 4504
Score = 64.1 bits (149), Expect = 1e-09
Identities = 125/609 (20%), Positives = 232/609 (38%), Gaps = 70/609 (11%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G+ +C++E + +W + + PS + ++ +D + ++ + D G ++
Sbjct: 4241 EGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNL-IFSEDYKLIKILSTRL--SDQGEYS 4296
Query: 583 CVAKNAAGFASSTTEL-------IVEAPLSD---HGSEMTVXXXXX-----XXXXXXXAD 627
C A N AG A+ T L I+E P + G ++T+ +
Sbjct: 4297 CTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNE 4356
Query: 628 IL--EGIPPTFSKKPKA---QYVDEGSDILLECRL---VAIPEPDIAWLFK-GEEIVPDE 678
+L G+ T + K K+ + + C+ VA E DI + E+VP+
Sbjct: 4357 LLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPER 4416
Query: 679 -NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737
N+S + + C+ I + N E L L I+ +
Sbjct: 4417 MNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGF 4476
Query: 738 IEPLKSMIVRQGESVILSAQVVGNP--RPTITW--C-KNNKPVKALPTKSDGDT--HSIT 790
+ G+ + +V P RP W C + KP K GDT +
Sbjct: 4477 YHCIAKS--DAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQ 4534
Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
+L K V+D + A +S + + +A P FI + + T +
Sbjct: 4535 LLPWKDVEDSSLNGSIAYRCMPGPRSSRTVLL------HAAPQ-FIVKPKNTTAAIGAIV 4587
Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
+L P P+ITW ++ ++I S+ F+ L +T ++S DSG+Y C+A N
Sbjct: 4588 ELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT-LNSTSDSGEYTCMAQN 4641
Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN----KKE 966
S G S+ A + +D + K S + E +++ W +N K
Sbjct: 4642 SVGSSTVSAFINVDNNILPTPK--PSSNQKNVAVITCYERNQAYSRGLTWEYNGVPMPKN 4699
Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRKL 1023
++G+ + G D+ + C V+++ + + E +PE ++ +
Sbjct: 4700 LAGI---HFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPHLTSAFEGVPE-VKTI 4755
Query: 1024 QDFEVKEKDVAILEVEINSE--TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
EV D +L+ E+ S+ T VVW ++ + + Y L + N
Sbjct: 4756 DKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPN----NSLVLLNVEK 4811
Query: 1082 HDEGEYSCI 1090
+DEG Y C+
Sbjct: 4812 YDEGVYKCV 4820
Score = 61.7 bits (143), Expect = 6e-09
Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 31/294 (10%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F KPK G+ + L C P P I W G+ ++ D +A S
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAY--------S 4620
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
LK+T G YT +A N G +++ + + P+ K++ +VI
Sbjct: 4621 HLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV------AVI 4674
Query: 754 LSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
+ +TW N P+ K L + S+ IL +K D +YT K N
Sbjct: 4675 TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITWYRN 869
+ E E + ++ V ++ L VT +P+ + + W +N
Sbjct: 4735 RRHSIPHLTSAFEGVPE--------VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN 4786
Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
++ + + I + N LV+ NV+ + D G YKCVASNS GK+ ++ +
Sbjct: 4787 DQKMLDDDAI---YVLPNNSLVLLNVE-KYDEGVYKCVASNSIGKAFDDTQLNV 4836
Score = 57.6 bits (133), Expect = 9e-08
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 19/271 (7%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
PQ I K+ G V L G P PTITW K+ K ++ + +T+
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL--- 4626
Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
D G YT A+NS G + SA I V+ +P IT E+ + +
Sbjct: 4627 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERN--QAYS 4684
Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
R +TW N + P +F N LVI + S + GD + +
Sbjct: 4685 R-------GLTW-EYNGVPMPKNLAGIHF-MNNGSLVILDT-SSLKEGDLELYTCKVRNR 4734
Query: 915 SSHG-ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDH 972
H +T E V VK + K E G +V+L+C+ TS ++T K + +D
Sbjct: 4735 RRHSIPHLTSAFEGVPEVKTIDK-VEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDD 4793
Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
+ I D GV KC+ +
Sbjct: 4794 -DAIYVLPNNSLVLLNVEKYDEGVYKCVASN 4823
Score = 56.0 bits (129), Expect = 3e-07
Identities = 61/321 (19%), Positives = 120/321 (37%), Gaps = 22/321 (6%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P + P GS L C + P+P I+W G +I EN I +D
Sbjct: 4136 PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGEN-GHTIGAD----- 4189
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
L I ++ + Y A N G +L ++ K + +G
Sbjct: 4190 GTLHIEKAEE-RHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYING---SEGTET 4245
Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ + + + +W KN P+ + + + + ++ D+G Y+ A N G
Sbjct: 4246 VIKCE-IESESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAG 4304
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
A + V P + R + V + + L + P P+ITWY++NE+
Sbjct: 4305 NATQKTNLNV-------GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNEL 4357
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
++ + + + + ++ +++ S +G Y C A N + + + + +
Sbjct: 4358 LT-NTGVDETATTKKKSVIFSSI-SPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPE 4415
Query: 933 HLQKSYETEEGKTVILECQTS 953
+ S T +TV L C +
Sbjct: 4416 RMNVS--TNPRQTVFLSCNAT 4434
Score = 54.8 bits (126), Expect = 6e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 24/347 (6%)
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
TI ++ DAG Y+ R+ +N G+ V+ V + P P I + + S+ + E
Sbjct: 485 TIPELSLKDAGEYECRVISNNGNYSVKTRVETRESP-----PEIFGVRNVSVPL--GEAA 537
Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA-VNEVDISDA 1464
ST VE + T +V N T+ + N + RA A V E +A
Sbjct: 538 FLHCSTRSAGEVEIRW--TRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNA 595
Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
+ + ++ ++ P+V+ +++ E + L+C G P+P+V WY G+ L
Sbjct: 596 GGMST--RKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLN 653
Query: 1525 --AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
++ Y+C A + G+ + + + P + I I+
Sbjct: 654 DYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEI----IQN 709
Query: 1583 KHKVGDEWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
K VG V+ I G P P++ W+KNG L +Y K + I K
Sbjct: 710 KMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDY---IKINEGQLHIMGAKDED 766
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
+ Y+ N AG L V P+ E P +R VT++
Sbjct: 767 AGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQ 813
Score = 53.2 bits (122), Expect = 2e-06
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C N G+ E + + + + PV + QK + ++ + G P P VIW
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+GN + DK + E S++RI++L S++ + A N AGT+S + ++ P+
Sbjct: 1773 IDGNDV--DKSW--LFDESLSLLRIEKL-TGKSAQISCTAENKAGTASRDFFIQNIAAPT 1827
Query: 1668 -KPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
K EG I RES TI P+ G ++T
Sbjct: 1828 FKNEGD--QETIFRESETITLDCPVSLGDFQIT 1858
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
K +G EC VEGYP PQ++W R ++ Y D + T++ E D+
Sbjct: 4053 KQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII--EARSLDS 4110
Query: 579 GTFTCVAKNAAGFASS--TTELIV 600
G + C A N AG A T E++V
Sbjct: 4111 GIYLCSATNEAGSAQQAYTLEVLV 4134
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
PI + + +T G V+ +C VE P +TWFR+ I D + Y + + TL
Sbjct: 1362 PIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAI--GTDTKGYVVESD-GTL 1418
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
VI+ EDA +TC A N AG A + ++ V A
Sbjct: 1419 VIQSASVEDATIYTCKASNPAGKAEANLQVTVIA 1452
Score = 48.0 bits (109), Expect = 7e-05
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ T E S P V +G C+V G P P + W + +P +
Sbjct: 3116 EQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDG---EPYTSDLL 3172
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ ++ L +RE D GT+TC+A N AG + +TT++ V P
Sbjct: 3173 QFST-KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
Y C A N G + + P I + + HK GD+ + G+P P + WY
Sbjct: 4295 YSCTAANKAGNATQKTNLNVGVAPKI-MERPRTQVVHK-GDQVTLWCEASGVPQPAITWY 4352
Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
K+ L N T +K SVI + S + YT +A N ++ ++ L V P
Sbjct: 4353 KDNELLTNTGVDETATTKKKSVI-FSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 4410
Score = 47.2 bits (107), Expect = 1e-04
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T+ +AP +E+ R + G V C+ G P+P ITW++ ++ + +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET--A 4367
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+++ + P AG +TC A+N +LIV P
Sbjct: 4368 TTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIP 4409
Score = 45.2 bits (102), Expect = 5e-04
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 8/92 (8%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F+ K + G+ V+ C G P P ITW + +I+ S+ F++ Y + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-FEIAY-----SHL 4622
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ D+G +TC+A+N+ G SST +
Sbjct: 4623 KVTLNSTSDSGEYTCMAQNSVG--SSTVSAFI 4652
Score = 44.8 bits (101), Expect = 7e-04
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
V C+ G P+P++ W+ + + +Q+ D L IR+ D GT+ C A
Sbjct: 628 VNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSK---FLYIRDATHHDEGTYECRAM 684
Query: 587 NAAGFASSTTELIVEAP 603
+ AG A TT+L++ P
Sbjct: 685 SQAGQARDTTDLMLATP 701
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 508 MAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+AP F E +R G+ C +G P P ITW + I+P+ D +++D
Sbjct: 2475 VAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPN-DRYVFFDAGR- 2532
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGF--ASSTTELIV 600
L I + D G +TC+A N+ G +T E+I+
Sbjct: 2533 -QLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVII 2568
Score = 41.1 bits (92), Expect = 0.008
Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 25/102 (24%)
Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
+ VF KPT E VE G + + EC+++G+P+P I+W +K +
Sbjct: 3294 IDVFTKPTFETHETTFNIVE---------GESAKIECKIDGHPKPTISW------LKGGR 3338
Query: 555 DFQMYYDDDNVA------TLVIREVFPEDAGTFTCVAKNAAG 590
F M DN+ TL+I + D G +TCVA N+ G
Sbjct: 3339 PFNM----DNIILSPRGDTLMILKAQRFDGGLYTCVATNSYG 3376
Score = 40.3 bits (90), Expect = 0.015
Identities = 95/459 (20%), Positives = 174/459 (37%), Gaps = 45/459 (9%)
Query: 1002 KDQETSTMLVVKETIPE---FIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEII 1056
K Q T L ++ +P+ F + + +K +A ++ +N S+ +W E
Sbjct: 4456 KYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQK-IATRKLIVNKPSDRPAPIWVECDEKG 4514
Query: 1057 KPKKNKYDFEKRGH-------IRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
KPKK +Y ++ + + ++S++ Y C+ S + ++ P+
Sbjct: 4515 KPKKTEYMIDRGDTPDDNPQLLPWKDVEDSSLNGSIAYRCMPGPRS--SRTVLLHAAPQF 4572
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
I + +N G A E+ + + W KDG I+ S + LK+
Sbjct: 4573 IVKPKNTTAAIG--AIVELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKVT 4625
Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
D+GEY+C VG+S +A + V+ N L P+ N E
Sbjct: 4626 LNSTSDSGEYTCMAQNSVGSSTVSAFINVD----NNILPTPKPSSNQKNVAVITCYERNQ 4681
Query: 1223 E-TLDVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKL 1279
+ +TW Y + ++ +++ L E D YTC + + + +
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHSIPH 4741
Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
E P++ ++ + G V L D + P +V +K +K
Sbjct: 4742 LTSAFEGVPEVKTIDK-VEVNNGDSVVL--DCEVTSDPLTTHVVWTKNDQKMLDDDAIYV 4798
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
+ SL + VE D G+YK N+ G A + + + + P + + S INI
Sbjct: 4799 LPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP----LTGFEGSGINI 4854
Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
D+ N G S+ + E +T I+ + T T T
Sbjct: 4855 --DDSSNAGGSSRREAYKKENEDASTTTITTTSPTTTTT 4891
Score = 39.9 bits (89), Expect = 0.019
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
+ KP KN T +EL C G P P +TW +DGK ++ +K
Sbjct: 4573 IVKP-KNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIA-YSHLKVTLNSTS 4630
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGI 1567
Y C+A N G S + +
Sbjct: 4631 DSGEYTCMAQNSVGSSTVSAFINV 4654
Score = 39.1 bits (87), Expect = 0.034
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 11/91 (12%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E + P ++ R +G+T CQV G P P +TW R K + F
Sbjct: 3209 TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNG---KEIEQFN---- 3261
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
L IR D G ++C+A N AG A
Sbjct: 3262 ----PVLHIRNATRADEGKYSCIASNEAGTA 3288
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P ++ +C +G P PQ+ W TA+ + + D + I V D G
Sbjct: 3965 PAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ---INNVSLSDKGV 4021
Query: 581 FTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613
+TC A+N AG + + +V+AP+ +G V
Sbjct: 4022 YTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV 4055
Score = 37.9 bits (84), Expect = 0.078
Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 26/201 (12%)
Query: 408 FEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKG 467
FE V R GDT+ + AE+ ++ V + D S Q+ K+ EK
Sbjct: 2763 FEKEREEVVARVGDTMLLTCN--AESSVPLSSVYW---HAHDESVQNGVITSKYAANEKT 2817
Query: 468 WVPAQYLMDENNY---TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPD 523
+D+ + T + + +K KL V E P ++Q + PI +
Sbjct: 2818 LNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIIL---------- 2867
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G + +C G P P I + + + S + + +TLVI E G +TC
Sbjct: 2868 GKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIG-----STLVIDNPQKEVEGRYTC 2922
Query: 584 VAKNAAGFASSTTELIVEAPL 604
+A+N AG S +++VE L
Sbjct: 2923 IAENKAG--RSEKDMMVEVLL 2941
Score = 37.5 bits (83), Expect = 0.10
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDM 688
EG+P K V+ G ++L+C + + P + W ++++ D+ I V +
Sbjct: 4747 EGVPEV--KTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPNNS- 4803
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
L + NV+K+ EG Y VA N G+A L + G+ P
Sbjct: 4804 ------LVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP 4843
Score = 35.9 bits (79), Expect = 0.32
Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
T E +P + +R P G C +I W R A + + +
Sbjct: 512 TRVETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTER--- 568
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
+ TL I V DAG + C+A+NA G ++ L I+E P
Sbjct: 569 NPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPP 611
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P + W K+G KL D ++ I S +++ S S +YT A N+ G+S+V
Sbjct: 4595 GPPHPTITWAKDG-KLIEDSKFEIA----YSHLKVTLNSTSDSGEYTCMAQNSVGSSTVS 4649
Query: 1658 VTLKV 1662
+ V
Sbjct: 4650 AFINV 4654
Score = 33.9 bits (74), Expect = 1.3
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 523 DGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G + C EG P P W F Q + K + ++ ++++ T+V+ V G +
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLPKEA----VFVNNNH--TVVVNNVTKYHTGVY 1982
Query: 582 TCVAKNAAGFASSTTELIVEA-PLSDHG---SEMTVXXXXXXXXXXXXADIL-EGIPPTF 636
C A N G A T + V P + G SE+TV D + GI T
Sbjct: 1983 KCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 637 SKKP 640
+ KP
Sbjct: 2043 NGKP 2046
Score = 33.9 bits (74), Expect = 1.3
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+ +++ C+V G P P +TW + + + Q+ + +V E+ G++
Sbjct: 2112 ENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQF-KIVHAEI--AHKGSYI 2168
Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608
C+AKN G A + ++ I+ P+ G
Sbjct: 2169 CMAKNDVGTAEISFDVDIITRPMIQKG 2195
Score = 33.9 bits (74), Expect = 1.3
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
+G +V +C+V P + W + K D +Y +N +LV+ V D G +
Sbjct: 4762 NGDSVVLDCEVTSDPLTTHVVWTKNDQ--KMLDDDAIYVLPNN--SLVLLNVEKYDEGVY 4817
Query: 582 TCVAKNAAGFASSTTELIV 600
CVA N+ G A T+L V
Sbjct: 4818 KCVASNSIGKAFDDTQLNV 4836
Score = 32.7 bits (71), Expect = 3.0
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 510 PIFVEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P+FVE + + + + +CQV G P+P + W + S F D++++
Sbjct: 1736 PVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLF-----DESLSL 1790
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593
L I ++ + A +C A+N AG AS
Sbjct: 1791 LRIEKLTGKSA-QISCTAENKAGTAS 1815
Score = 31.5 bits (68), Expect = 6.8
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
TP GS C V GYP P I+W IK ++ D TL I E E
Sbjct: 4147 TPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGAD---GTLHI-EKAEERHL 4202
Query: 580 TFTCVAKNAAG 590
+ C AKN AG
Sbjct: 4203 IYECTAKNDAG 4213
>AY130758-5|AAN61521.1| 2693|Caenorhabditis elegans 301KDa_2 protein
protein.
Length = 2693
Score = 140 bits (340), Expect = 8e-33
Identities = 121/465 (26%), Positives = 198/465 (42%), Gaps = 30/465 (6%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K ++ + P F+E L T +G+ + EC V G P P ITW++ + Y
Sbjct: 854 KEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQY 913
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAG--FASSTTELIVEAPLSDHGSEMTVXXXX 617
D V+ L I V D G +TC A N+ G F T + +V+ LS + +T
Sbjct: 914 TDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK-VVDMGLSK--TRLTPVRSR 970
Query: 618 XXXXXXXXADILEGI--PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675
+ + I PP ++ V EG+ LLE + P P I W G+ +
Sbjct: 971 SRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVA 1030
Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---- 731
+ + + + LKI + G Y N+ G ++ ++ +
Sbjct: 1031 ESRTLRTYFDGRV----AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEH 1086
Query: 732 -KEPPQVIEPLKSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-- 787
+ P ++ L+ ++++ GE+ + Q NP + W N K ++ TKS+ T
Sbjct: 1087 VTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQ--QTKSNYKTRLF 1144
Query: 788 --SITILKPKKVKDE--GVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQ- 840
+ L + V DE G YT A N G TSA +T+ E + A P FI +
Sbjct: 1145 DDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKP 1204
Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
+I V E T+ + A + +P+P + W ++N + S+ I DG N +L++ +V E D
Sbjct: 1205 KINVVEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLE-D 1263
Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGK 944
G Y A N GK V++ K V K +K + +EGK
Sbjct: 1264 EGTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGK 1308
Score = 138 bits (334), Expect = 4e-32
Identities = 226/1028 (21%), Positives = 398/1028 (38%), Gaps = 137/1028 (13%)
Query: 473 YLMDENNYTQYLQKKLNE----KIDKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPD-GST 526
Y E + QY+ K N+ + + V E P + E + P FV+KL+ G T
Sbjct: 1049 YEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGET 1108
Query: 527 VQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
F CQ P Q+ W A+ + +++ DDN ATLVI V E GT+T VA
Sbjct: 1109 ATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVA 1168
Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
N G ++ +L + GSE I+E KPK V
Sbjct: 1169 NNQFGDVHTSAQLTIS------GSEAKKIAASLPYF------IIE-------LKPKINVV 1209
Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG+ + ++ L P P++ WL E+V + I + + + L + +V E
Sbjct: 1210 -EGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQ----LLVRDVGLEDE 1264
Query: 706 GTYTVVAVNREGE----ASLPIVLKIKTGEKEPPQVIE--------PLKSMIVRQGESVI 753
GTYT+ A N +G+ + + + EK+ + +E P + + R +
Sbjct: 1265 GTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASK 1324
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITI-LKPKKVKDEGVYTLKAE 808
+ P+ + + + P + + G T S+ + +K E ++ + +
Sbjct: 1325 TEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGK 1384
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N +G+ E S + + + P I+ +I ++ + P PS+ WY+
Sbjct: 1385 NKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK 1444
Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
N I P E I + I N+ S+ ++G + C+ N G++S +VTI +
Sbjct: 1445 ENLQIVPDEKIDVATTSTSS---ILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPA 1501
Query: 929 TF------------VKHLQKSYETEE---GKTVILECQ-TSHTVST-KWYHNKKEISGMD 971
+ V LQK+ E G+ ++L C+ +S + ST W+ + + I
Sbjct: 1502 SLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAG 1561
Query: 972 HREIIQEGRXXXXXX-XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI----PEFIRK 1022
E+ + + D G +C+V ++ E+ + V++ P F
Sbjct: 1562 RYELSSDKKSNHKLVCHAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSAT 1621
Query: 1023 LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
L D LE ++ A +V W +DGE I + + KL I
Sbjct: 1622 LSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAES 1681
Query: 1082 HDEGEYSC----ILRDESCTAEVTVVELPPE----IITRLQNQK---------------V 1118
D G Y C + +S ++ V + + +I + ++K V
Sbjct: 1682 DDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEV 1741
Query: 1119 NKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDD-AGE 1175
N+ + T + + V W KDG EI +N I + G + I +C + +G
Sbjct: 1742 NESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGI 1801
Query: 1176 YSCEVGNSKCTAILTVE------EPSIN-------FTLRLPEFILV---PANTDAYLTVE 1219
+SC+ N T I + +P+ FT+ L + +V P +T
Sbjct: 1802 FSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGS 1861
Query: 1220 IPDETLDVTWYK----KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA-- 1273
P+ TL+ + K ++ T +T K L + + + Y C+ ++
Sbjct: 1862 -PEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSG 1920
Query: 1274 KSTTKLKVEVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
++TT+ + V E PP+ V ++ + V+ FP P+ W N K
Sbjct: 1921 QATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKK 1980
Query: 1328 IKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD---KPSP 1383
I + K K + S + S L+IK V G+Y + N G + + D K P
Sbjct: 1981 INEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDERRKAEP 2040
Query: 1384 PGKPNILE 1391
P ++LE
Sbjct: 2041 PQFKHVLE 2048
Score = 135 bits (326), Expect = 4e-31
Identities = 139/503 (27%), Positives = 207/503 (41%), Gaps = 46/503 (9%)
Query: 435 EAINLVEGERLYILDTSNQDWWYVQKH--LTEEKGWVPAQYLMDENNYTQYLQ-KKLNEK 491
E I L G + I + D++Y++ H T +KG+ +E T + L K
Sbjct: 2204 EGIILETGNKYSIYNDG--DFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNK 2261
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAII 550
D K S +++ AP F+E L + + ++ EC V YP I W R + +
Sbjct: 2262 EDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRL 2321
Query: 551 KPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
P D + M YD + A+L V P D GT+ C A N G A + L V
Sbjct: 2322 LPQADRYTMSYDGE-CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSG------- 2373
Query: 610 EMTVXXXXXXXXXXXXADILEGIPPTF--SKKPKAQYVDEGSDILLECRLVAIPEP-DIA 666
+ EGIPP F K + V +GS + L LV EP I
Sbjct: 2374 --------------VDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIR 2419
Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
WL IV + S + +M L I +V G YTV A N+ G A + L
Sbjct: 2420 WLRNKVTIVDSPSFSYSRSENMVF----LTIADVFPEDGGEYTVEAKNQSGIARCTMQLD 2475
Query: 727 IKTGEK----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALP 779
++ E+ E P+V + + G SV L A+V+G+P P I+W K + + +
Sbjct: 2476 VRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYM 2535
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
+++GD + I + D G Y L A N G A +TV + T+ P F
Sbjct: 2536 MRNEGDKFILRIANVTRA-DAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESP 2594
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSE 898
+ EK +L A + P P+ W Y NE+I + T N L+I +VD +
Sbjct: 2595 ISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKK 2654
Query: 899 IDSGDYKCVASNSAGKSSHGARV 921
G+Y C N G+ A +
Sbjct: 2655 -HFGEYLCTIRNQNGEELANAMI 2676
Score = 129 bits (312), Expect = 2e-29
Identities = 133/630 (21%), Positives = 248/630 (39%), Gaps = 73/630 (11%)
Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
++ PP + L + V +GN+ E+E+ + W+ DG + S ++ DG+
Sbjct: 985 IQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVA 1044
Query: 1162 KLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSI--------NFTLRLPEFILVP 1209
LKIY+ + G+Y C+V N + AI+ VE P F +L + +L
Sbjct: 1045 FLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 1104
Query: 1210 ANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKF--TLISDVKKRTLIIRKCTEDDQCEY 1266
A A T + + V W ++ T+ T + D TL+I T++ Y
Sbjct: 1105 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 1164
Query: 1267 TCVLL----DAKSTTKLKVEVVE-------FPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
T V D ++ +L + E P I++ + + + G+ +++ D P
Sbjct: 1165 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 1224
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEM 1373
P W+ ++ + + + D + L ++ V D G Y + EN G + E+
Sbjct: 1225 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 1284
Query: 1374 NVT----ILDK------------PSPPGKPNILEIDSSS----INICWDEP-ENTGNSTI 1412
+VT + +K PG+P + +S + + +D P E +S
Sbjct: 1285 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADS-- 1342
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
Y VE + D EW+S + + I+ L N+ Y FR N+ + + SE T K
Sbjct: 1343 --YEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLK 1400
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYE 1530
+ T+ P I +++ E+ F G P P V WY++ ++ +
Sbjct: 1401 TASVGQAPQFTI-SPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVAT 1459
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---------------VITI 1575
+ C+ N+ G+ SC V I KP V T+
Sbjct: 1460 TSTSSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTL 1519
Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634
+ + G + ++T I V W+K+ ++E+ Y +++ +K++ +
Sbjct: 1520 QKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHA 1579
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
++ + KY +N G + E + V D
Sbjct: 1580 VQSQDTGKYRCVVTNKYGYAESECNVAVED 1609
Score = 128 bits (310), Expect = 3e-29
Identities = 180/773 (23%), Positives = 292/773 (37%), Gaps = 104/773 (13%)
Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543
++KK + K K+ V E E M P F L+ G P P + W
Sbjct: 535 IEKKKDRKTSKVVVIE----EMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDW 590
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ I + + D L I V D G + V KNA G S +L V P
Sbjct: 591 YHNGEHISINDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIP 650
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP 663
+ P+F K+ E + LE + A P P
Sbjct: 651 DGQYA-------------------------PSFGKQLSDVKCSESDILKLEVNIQANPAP 685
Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+I W EI ++ + + Y L I + G Y VA N+ G+A
Sbjct: 686 EINWFRNESEIEHSQHHRLQFDDGSGNYS--LTIIDAYAEDSGEYKCVAKNKIGKAHTVC 743
Query: 724 VLKIKT----------GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
++I+ G K P ++ V QG + L V G P P I W K++K
Sbjct: 744 CVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDK 803
Query: 774 PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
P+ + + T+ + + D+G Y +AEN G+A++ +V+ ++E +++
Sbjct: 804 PIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVR 863
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE-----N 887
P F+ + E + L VT P+P+ITWY++ + + Q D + N
Sbjct: 864 PKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLN 923
Query: 888 IELVITNVDSE--------------------IDSGDYKC----VASNSAGKSSHGARVTI 923
I V+ N D E +D G K V S S +S + V
Sbjct: 924 IMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGG 983
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRX 981
++++ V EG +LE + T + +WYH+ K ++ +GR
Sbjct: 984 EIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRV 1043
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET--------IPEFIRKLQDFEVK 1029
G C V ++ ET ++VV+ +P F++KLQD +K
Sbjct: 1044 AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK 1103
Query: 1030 EK-DVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEK-RGHIRKLYIRNTSVHDEGE 1086
+ A + + A VVW +G+ ++ K+ Y + L I N + G
Sbjct: 1104 TAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 1163
Query: 1087 YSCILR----DESCTAEVTV--------VELPPEIITRLQNQKVNKGNKATFEIELT-KG 1133
Y+ + D +A++T+ P I L+ K+N AT I+ G
Sbjct: 1164 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELK-PKINVVEGATLSIQADLNG 1222
Query: 1134 DAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
+ V W KD SE+ S+ IQ+ DG +L + D L+D G Y+ N K
Sbjct: 1223 SPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEK 1275
Score = 123 bits (297), Expect = 1e-27
Identities = 121/517 (23%), Positives = 219/517 (42%), Gaps = 39/517 (7%)
Query: 510 PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F+ K +P+ + +++ + + G P PQ+ W ++ I++ + +Y D D L
Sbjct: 2167 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGD-FYYL 2225
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
+ V D G + C A N G + T+E+ V D +++ ++
Sbjct: 2226 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 2285
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESD 687
L G ++Q + + +EC + A P I W ++P + +++ + +
Sbjct: 2286 LPG---------RSQ-ANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGE 2335
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL----KS 743
C+ LK +V EGTY AVN G A + L++ + + I PL K
Sbjct: 2336 ----CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKI 2391
Query: 744 MIVRQ---GESVILSAQVVGNPRP-TITWCKNNKPVKALPTKSDGDTHSITILKPKKV-- 797
VR+ G V L+A++V P I W +N + P+ S + ++ L V
Sbjct: 2392 KSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFP 2451
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARV 856
+D G YT++A+N GIA + + V A+ + F+ T + G +++L A+V
Sbjct: 2452 EDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKV 2511
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
+P P I+W + + ++ E +G+ L I NV + D+G Y+ A N +G+++
Sbjct: 2512 IGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANV-TRADAGKYELTAINPSGQAN 2570
Query: 917 HGARVTIDVEKVTFVKHLQK------SYETEEGKTVILECQTSHT--VSTKWYHNKKE-I 967
+T+ V+ V K S +T E L S T + +W++N E I
Sbjct: 2571 AELELTV-VQSTKTVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI 2629
Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
G+D I G C +++Q
Sbjct: 2630 DGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTIRNQ 2666
Score = 108 bits (259), Expect = 5e-23
Identities = 114/496 (22%), Positives = 201/496 (40%), Gaps = 42/496 (8%)
Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ-FECQVEGYPRPQITWFRQTA-IIKPSQ 554
VFE+ + + AP ++L G + C V+G P P++ W++ + PS
Sbjct: 414 VFERNIAFDTDAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSM 473
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614
+ +Y++ +A L ++ + DAG +TC A N G + +L V+A T
Sbjct: 474 KYDSFYNE-GLAELTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSP 532
Query: 615 XXXXXXXXXXXADI-----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
+ + + +PP F + G +L +PEP + W
Sbjct: 533 AVIEKKKDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYH 592
Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
GE I +++ + + D Y L I +V EG + V N GE L +
Sbjct: 593 NGEHISINDS-NYLRKHDKGRY--ELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVI 649
Query: 730 GEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSD 783
+ + P + L + + + + L + NP P I W +N ++ L
Sbjct: 650 PDGQYAPSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDG 709
Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE------ENAEPPLFIN 837
+S+TI+ +D G Y A+N G A T + +EE + ++ P F
Sbjct: 710 SGNYSLTII-DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRF-- 766
Query: 838 RFQEITVKE--KGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
R Q T +E +G + LV V+ P P+I W ++++ I S ++ +G +I
Sbjct: 767 RMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGA 826
Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-------ETEEGKTVI 947
D D G Y C A N G + + +++++ H++ + T EG ++
Sbjct: 827 RDD--DQGRYVCEAENIHGVAQSFS--VVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMV 882
Query: 948 LE-CQTSHTVST-KWY 961
LE C T + T WY
Sbjct: 883 LECCVTGKPIPTITWY 898
Score = 108 bits (259), Expect = 5e-23
Identities = 124/516 (24%), Positives = 206/516 (39%), Gaps = 72/516 (13%)
Query: 638 KKPKAQYVDEGSDIL--LECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSV 694
KK V D++ L C + +P P + W +E+ VP S+ +S + +
Sbjct: 430 KKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVP----SMKYDSFYNEGLAE 485
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE------KEPPQVIEPLKS----- 743
L + N+ + G YT A N G L +K E K P VIE K
Sbjct: 486 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSK 545
Query: 744 -MIVRQ-------------------GESVILSAQVVGNPRPTITWCKNNKPVKALPT--- 780
+++ + GE IL P PT+ W N + + +
Sbjct: 546 VVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYL 605
Query: 781 -KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
K D + + IL DEG + +N+ G E+ A +TV P + A P F +
Sbjct: 606 RKHDKGRYELHILSVDST-DEGKWKAVGKNAFGECESEAKLTVVIPDGQYA--PSFGKQL 662
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ E +KL + NP P I W+RN I S+ FD + +T +D+
Sbjct: 663 SDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYA 722
Query: 900 -DSGDYKCVASNSAGKSSHGARVTIDV------EKVT------FVKHLQKSYETEEGKTV 946
DSG+YKCVA N GK+ V I+ +K+ F L E +G +
Sbjct: 723 EDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADL 782
Query: 947 ILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD- 1003
L C S T + KW + K I M ++++ E D G C ++
Sbjct: 783 TLVCSVSGTPHPNIKWTKDDKPID-MSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENI 841
Query: 1004 ---QETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
++ +++ +KE + P+F+ L + E + +LE + + + W +DG
Sbjct: 842 HGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDG 901
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
+ + + R + +L I N ++D+GEY+C
Sbjct: 902 LKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTC 937
Score = 93.9 bits (223), Expect = 1e-18
Identities = 155/717 (21%), Positives = 281/717 (39%), Gaps = 84/717 (11%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN-KYDFEKRGHIRKL 1074
P R L D V E + +LEVE++ T + W DG+++ + + F+ R K+
Sbjct: 989 PVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKI 1048
Query: 1075 YIRNTSVHDE--GEYSCILRDESCTAE---VTVVELP---------PEIITRLQNQKVNK 1120
Y H+E G+Y C + ++ E + VVE P P + +LQ+ +
Sbjct: 1049 Y----EAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 1104
Query: 1121 -GNKATFEIELTKGDAL-VRWFKDGSEIQF--SNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
G ATF + A V W +G +Q SN+ D L I + + G Y
Sbjct: 1105 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 1164
Query: 1177 SC----EVGNSKCTAILTVE-EPSINFTLRLPEFIL-----VPANTDAYLTVEIP---DE 1223
+ + G+ +A LT+ + LP FI+ + A L+++
Sbjct: 1165 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 1224
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+V W K S + ++++ + D L++R +D+ YT + K + EV
Sbjct: 1225 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 1284
Query: 1284 VEFPPKIVDYEREYR----------------IKRGSDVTLLVDY-QAFPQPNDEWIVNSK 1326
K V ++E + + R S + AF P++ + +
Sbjct: 1285 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADSYE 1344
Query: 1327 IIKKCKHTKPSID---SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
+ ++C + + +KS L IK + I+++ +N G + + L S
Sbjct: 1345 VERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLKTASV 1404
Query: 1384 PGKPNILEIDSSSINICWDEP-----ENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQ 1437
P S I D+ E +G T + + E +I E I V T +
Sbjct: 1405 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVA--TTST 1462
Query: 1438 TSIQNLKTNSSY-RFRAYAVNEVDISDAS-ETTEYYKV--IKETKIQS------PTVEKP 1487
+SI NLK+ F NE+ + AS + T + K ++ T S PT++K
Sbjct: 1463 SSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKA 1522
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXX 1542
L N + + + I LTC + V W++D +++++A + ++
Sbjct: 1523 LNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQS 1582
Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ--KPVITISNEDIKQKHKV-GDEWLVTAVIEGI 1599
Y+C+ N +G E+ C V ++ K + + + + G + +EG
Sbjct: 1583 QDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGS 1642
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS 1655
P PEV W K+G ++ + T E + + I + + Y A++ AG S
Sbjct: 1643 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDS 1699
Score = 72.9 bits (171), Expect = 2e-12
Identities = 89/420 (21%), Positives = 167/420 (39%), Gaps = 33/420 (7%)
Query: 1274 KSTTKLKV--EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-K 1330
+ T+K+ V E+++ PP ++ K G L+V P+P +W N + I
Sbjct: 541 RKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISIN 600
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKP 1387
+ D L I V++TD G +K +N G + E +T++ + +P
Sbjct: 601 DSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGK 660
Query: 1388 NILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNL 1443
+ ++ S +I E N + I + EI+ ++ ++ +I +
Sbjct: 661 QLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDA 720
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVI--KETKI---QSPTVEKPLKNITTEPN-E 1497
S ++ A N++ + +++ + KI ++P L P
Sbjct: 721 YAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGA 780
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRX-XXXXXXXXXXXXXXYKCIAFN 1554
D+ L C G P P + W +D K + + + +EN Y C A N
Sbjct: 781 DLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAEN 840
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKV---------GDEWLVTAVIEGIPPPEVI 1605
HG ++ VV I++ + + ++ K G+E ++ + G P P +
Sbjct: 841 IHGVAQSFSVVEIKE----AVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTIT 896
Query: 1606 WYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYK+G KL ++ T ++ S + I + + +YT EA N+ G T+KV D
Sbjct: 897 WYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 956
Score = 72.1 bits (169), Expect = 4e-12
Identities = 102/420 (24%), Positives = 173/420 (41%), Gaps = 44/420 (10%)
Query: 1002 KDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK 1057
KD++TS ++V++E I P F LQD E K + IL V + V W +GE I
Sbjct: 539 KDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHIS 598
Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAE--VTVV----ELPPEI 1109
+ Y + +L+I + DEG++ + ++ C +E +TVV + P
Sbjct: 599 INDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSF 658
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID--GKKQKLKIY 1166
+L + K ++ + E+ + A + WF++ SEI+ S H +L D L I
Sbjct: 659 GKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTII 718
Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEE------------PSINFTLRLPEFILVPA 1210
D +D+GEY C ++G + + +EE + F ++LP VP
Sbjct: 719 DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQ 778
Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
D L + ++ W K I+ + K + + TL I +DDQ Y C
Sbjct: 779 GADLTLVCSVSGTPHPNIKWTKDDKPIDMSNK-QVRHENGVCTLHIIGARDDDQGRYVCE 837
Query: 1270 ------LLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
+ + S ++K V+ PK ++ G+++ L P P W
Sbjct: 838 AENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITW 897
Query: 1322 IVNS-KIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
+ K+I + + + + D K S L I V D G Y N+ G V ++D
Sbjct: 898 YKDGLKLIIENRMLQYT-DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 956
Score = 70.1 bits (164), Expect = 2e-11
Identities = 80/320 (25%), Positives = 121/320 (37%), Gaps = 42/320 (13%)
Query: 1480 QSPTVEKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538
Q PT K L+++ + E TC P +V W +GK L+ K+ Y+ R
Sbjct: 1089 QMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNT 1148
Query: 1539 XXXXXXXXX------YKCIAFNDHGEVETSCVVGIQQKPVITISNE------DIKQKHKV 1586
Y +A N G+V TS + I I+ ++K K V
Sbjct: 1149 ATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINV 1208
Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + A + G P PEV+W K+ ++L + + ++++ YT
Sbjct: 1209 VEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYT 1268
Query: 1645 IEASNTAG----------TSSVEVTLKVYDK-----------PSKPEGPVIMREISRESV 1683
I A N G T S EV K K P +P P E V
Sbjct: 1269 ITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQV 1328
Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
T+ + P +G + Y +E+ PD W+ + +E I+ L N EY+FRV
Sbjct: 1329 TMAFDAP-SEGPAD--SYEVERRCPDQREWVSCGST-KSLELE-IKGLTPNTEYIFRVAG 1383
Query: 1744 QNPVGFSEALESEPIVIKTA 1763
+N G E E +KTA
Sbjct: 1384 KNKQGLGEWSEMTS-TLKTA 1402
Score = 70.1 bits (164), Expect = 2e-11
Identities = 106/437 (24%), Positives = 167/437 (38%), Gaps = 56/437 (12%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F+ K + +V E+ ++ L+ I+ V W+++G II NKY G L
Sbjct: 2167 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG-IILETGNKYSIYNDGDFYYL 2225
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL 1130
+ + S D+G Y+C + +CT+E+ V+ + ++ +K K KA IE+
Sbjct: 2226 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 2285
Query: 1131 TKG------------DALVRWFKDGSEIQFSNHIQL---------TIDGKKQKLKIYDCD 1169
G + V + S I N ++L + DG+ LK
Sbjct: 2286 LPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVT 2345
Query: 1170 LDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFIL---------VPANTDAYL 1216
D G Y+CE N +A+ L V N +P V + L
Sbjct: 2346 PGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVEL 2405
Query: 1217 TVEI--PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272
E+ E L + W + K I D+ F+ L I +D EYT +
Sbjct: 2406 AAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQS 2465
Query: 1273 --AKSTTKLKVE-----VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VN 1324
A+ T +L V V + P++ D+E R G V L P P W
Sbjct: 2466 GIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAG 2525
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K+ + K+ + K L I V DAG Y+L N G A+ E+ +T++
Sbjct: 2526 QKLNNEEKYMMRNEGDKFI-LRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTV 2584
Query: 1385 G-KPNILEIDSSSINIC 1400
G KP E S+ C
Sbjct: 2585 GAKPKFNE-SPISVQTC 2600
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/247 (25%), Positives = 96/247 (38%), Gaps = 20/247 (8%)
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
KT+ + +A N I++ + K + +P PL ++ L+C
Sbjct: 1797 KTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSC 1856
Query: 1504 IFGGVPQPKVTW-YRD--GKKLKTAKAT-------YENRXXXXXXXXXXXXXXXYKCIAF 1553
G P+P + W Y D G K+ +T + Y+CIA
Sbjct: 1857 NVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIAT 1916
Query: 1554 NDHGEVETSC--VVG-IQQKPV----ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
N G+ T C +VG + +P +D K E+ V + G P P++ W
Sbjct: 1917 NSSGQATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVE--LAGFPTPDLTW 1974
Query: 1607 YKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
Y N K+ K+ IT + TSV+ IK + + Y +EASN G L V D+
Sbjct: 1975 YHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDE 2034
Query: 1666 PSKPEGP 1672
K E P
Sbjct: 2035 RRKAEPP 2041
Score = 58.8 bits (136), Expect = 4e-08
Identities = 133/587 (22%), Positives = 225/587 (38%), Gaps = 86/587 (14%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F Q + +D + VE + + T V W ++ I P + K D L
Sbjct: 1408 PQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDE-KIDVATTSTSSIL 1466
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PE------IITRLQNQKV 1118
++ S + G ++C++ +E S + +VT+ P P+ ++ LQ
Sbjct: 1467 NLK--SQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALN 1524
Query: 1119 NKGNKATFEIELT-----KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDD 1172
N+ +A +I LT + ++ V WFKD I+ + +L+ D K KL + D
Sbjct: 1525 NESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQD 1584
Query: 1173 AGEYSCEVGN------SKCT-AILTVEE---PSINFTLRLPEFILVPANTDAYLTVEIPD 1222
G+Y C V N S+C A+ V + PS + TL IL N VE
Sbjct: 1585 TGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAIL-GHNITLECKVE-GS 1642
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTC------------- 1268
+V+W K I T + D L I K DD Y C
Sbjct: 1643 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSS 1702
Query: 1269 VLLDAKST-TKLKVEVVEFPPKIVDYEREYR-------IKRGSDVTLLVDYQAFPQPNDE 1320
+++ AK+T T + + + + + R R + TL+ P+P
Sbjct: 1703 MVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVT 1762
Query: 1321 WIVNSKIIKKCK---HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W+ + + I + H + D +S L + V + +GI+ + EN G E V I
Sbjct: 1763 WLKDGREILRTNRIYHHFVTGDGES-HLIAECVVSKTSGIFSCKAENPNGTVIAETQV-I 1820
Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK------ 1431
+ + P + + + D G+ T + V T EWI +
Sbjct: 1821 VQRMKPANQ--LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKI 1878
Query: 1432 NITKTQTS--------IQNLKTNSSYRFRAYAVNEVDISDASE-TTEYYKVIKETKIQS- 1481
N+T + T + LK+ R + + + + + TT+ Y ++ E +
Sbjct: 1879 NLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPA 1938
Query: 1482 --PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P K L++ T E IE + G P P +TWY + KK+ K
Sbjct: 1939 GPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGK 1985
Score = 56.4 bits (130), Expect = 2e-07
Identities = 71/365 (19%), Positives = 133/365 (36%), Gaps = 27/365 (7%)
Query: 1313 AFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
A+P + W NS +++ + S D + ASL V D G Y N G A
Sbjct: 2306 AYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVT 2365
Query: 1372 EMNVTI--LDKPSPPGKPNILE----------IDSSSINICWDEPENTGNSTIIYYVVEY 1419
MN+ + +D + G P + +D S + + + + + I + +
Sbjct: 2366 NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKV 2425
Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
+D+ + ++ +I ++ + A N+ I+ + + +
Sbjct: 2426 TIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVAD 2485
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXX 1535
++P V ++P +EL G P P ++W + G+KL K ++
Sbjct: 2486 EAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFIL 2545
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-------KPVITISNEDIKQKHKVGD 1588
Y+ A N G+ + + Q KP S ++ K
Sbjct: 2546 RIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRA 2605
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
E + A G P P W+ NGN+L + + Y IT+ + S + I + + H +Y
Sbjct: 2606 E--LRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTI 2663
Query: 1648 SNTAG 1652
N G
Sbjct: 2664 RNQNG 2668
Score = 56.0 bits (129), Expect = 3e-07
Identities = 85/380 (22%), Positives = 153/380 (40%), Gaps = 40/380 (10%)
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA------ 1098
A ++W R+ + P+ ++Y G L + + DEG Y+C +E +A
Sbjct: 2310 ASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVTNMNL 2369
Query: 1099 EVTVVE------LPPEI-ITRLQN-QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQF 1148
+V+ V+ +PP ++++ +KV G++ EL + +RW ++ I
Sbjct: 2370 QVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVD 2429
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPE 1204
S + L I D +D GEY+ E N ++CT L V + P
Sbjct: 2430 SPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPR 2489
Query: 1205 -FILVP-ANTDAYLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
F P +D ++VE+ + + ++W K + + EK+ + ++ K L I
Sbjct: 2490 VFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIAN 2549
Query: 1258 CTEDDQCEY--TCVLLDAKSTTKLKVEVVE------FPPKIVDYEREYRIKRGSDVTLLV 1309
T D +Y T + ++ +L++ VV+ PK + + + L
Sbjct: 2550 VTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRAELRA 2609
Query: 1310 DYQAFPQPNDEWIVN-SKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P W N +++I +T S D+ S SL I V+ G Y + N G
Sbjct: 2610 SFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNS-SLLINSVDKKHFGEYLCTIRNQNG 2668
Query: 1368 HADVEMNVTILDKPSPPGKP 1387
+ N IL + S P
Sbjct: 2669 --EELANAMILSEGSSAALP 2686
Score = 54.8 bits (126), Expect = 6e-07
Identities = 165/857 (19%), Positives = 306/857 (35%), Gaps = 104/857 (12%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF------RQTAIIKPS 553
KP ++ ++AP F L +G C V G P P + W + + +
Sbjct: 1825 KPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSST 1884
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
D+ VA L V E GT+ C+A N++G A++ L+V LSD +
Sbjct: 1885 TDWTECRFG-KVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLV-GELSDEPAGPPR 1942
Query: 614 XXXXXXXXXXXXADILE------GIP-PTFSKKPKAQYVDEGSDILLE-----CRLVAIP 661
+ +E G P P + + ++EG D+ + +++I
Sbjct: 1943 FVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIK 2002
Query: 662 EPDIAWLFKGEEIVPDENISVAIE-------SDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
+A L G V NI + SD + +V + VA +
Sbjct: 2003 NVSLASL--GMYFVEASNIHGVLRTAGRLNVSDERRKAEPPQFKHVLEPVLAVQPKVAFS 2060
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-NK 773
E + + + P ++ L+ M ++ G S ++ ++ RP + + +K
Sbjct: 2061 EEHPRASSSAATARVKKGAAPMFLQGLEDMDLKAGASAAVAGKLGRKLRPHRSTTNDADK 2120
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
KAL S+ + +P+ D + E++ A + + P
Sbjct: 2121 LAKAL-------AQSLRLDEPRASIDS-----RPESAANAALDEVRAAINSRNKRVCRPK 2168
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
+ ++E +++L ++ NP+P + W + I+ + DG+ L +
Sbjct: 2169 FMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVH 2228
Query: 894 NVDSEIDSGDYKCVASNSAG-------------KSSHGARVT-----IDVEKVTFVKHLQ 935
+V S D G Y C A+N+ G K A+V + + F++ L
Sbjct: 2229 HV-STFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLP 2287
Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXX 992
+ +++ +EC S S W N + + D + +G
Sbjct: 2288 GRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG 2347
Query: 993 DVGVIKCIVKDQ----ETSTMLVVKETIP---EFIRKLQDFE-VK--EKDVAILEVEI-- 1040
D G C ++ T+ L V P E I L FE +K K V VE+
Sbjct: 2348 DEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAA 2407
Query: 1041 ----NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES- 1095
SE + W R+ I + + + + ++ L I + D GEY+ +++S
Sbjct: 2408 ELVQASEPLQIRWLRNKVTIVDSPS-FSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSG 2466
Query: 1096 ---CTAEV-------TVVELPPEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGS 1144
CT ++ +V + P + + + G + + D ++ W K G
Sbjct: 2467 IARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQ 2526
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-- 1202
++ + +G K L+I + DAG+Y N A +E + T +
Sbjct: 2527 KLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGA 2586
Query: 1203 -PEFILVPANTD------AYLTVEIPDETLDV-TW-YKKKSVIEDTEKFTLISDVKKRTL 1253
P+F P + A L W Y +I+ + +T+ S +L
Sbjct: 2587 KPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSL 2646
Query: 1254 IIRKCTEDDQCEYTCVL 1270
+I + EY C +
Sbjct: 2647 LINSVDKKHFGEYLCTI 2663
Score = 54.0 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 79/204 (38%), Gaps = 20/204 (9%)
Query: 1482 PTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGK---KLKTAKATYENR-XXXX 1536
P V +PL + T TE N ++ L G P P + WY DGK + +T + ++ R
Sbjct: 989 PVVTRPLADATVTEGNREL-LEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLK 1047
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ---------QKPVITISNEDIKQKHKVG 1587
Y C N G VET +V ++ Q P +D+ K G
Sbjct: 1048 IYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK-TAG 1106
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK---EKTSVIRIKELKRSHSSKYT 1644
+ T P +V+W NG L+ K N T+ + T+ + I+ + YT
Sbjct: 1107 ETATFTCQSYANPAAQVVWLHNGKALQQTKS-NYKTRLFDDNTATLVIENVTDELCGTYT 1165
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSK 1668
A+N G L + +K
Sbjct: 1166 AVANNQFGDVHTSAQLTISGSEAK 1189
Score = 53.2 bits (122), Expect = 2e-06
Identities = 89/412 (21%), Positives = 155/412 (37%), Gaps = 43/412 (10%)
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKL 1360
G + L + + W + + I+ + S D KS L V++ D G Y+
Sbjct: 1531 GQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRC 1590
Query: 1361 RLENNCGHADVEMNVTILD--KPSPPGKPNILEIDSSSI---NICWDEPENTGNSTIIYY 1415
+ N G+A+ E NV + D K P L DS++I NI + + + +
Sbjct: 1591 VVTNKYGYAESECNVAVEDVTKFIAPSFSATLS-DSTAILGHNITLECKVEGSPAPEVSW 1649
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
+ + I TT I + K S Y + ++ T+ + K
Sbjct: 1650 TKDGERISTTRRIRQTQDENGNCKLSISKAESD-DMGVYVCSATSVAGVDSTSSMVMIAK 1708
Query: 1476 ETKIQSPTV---------EKP----LKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGK 1520
T S V EKP E NE + T I V P+P VTW +DG+
Sbjct: 1709 TTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGR 1768
Query: 1521 K-LKTAK-----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVI 1573
+ L+T + T + + C A N +G V V +Q+ KP
Sbjct: 1769 EILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPAN 1828
Query: 1574 TISNEDIKQKHKVGDEWLV-------TAVIEGIPPPEVIWY---KNGNKL---ENDKEYN 1620
++N K + D +V + + G P P + W +G+K+ + ++
Sbjct: 1829 QLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWT 1888
Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
K + ++ + + R Y A+N++G ++ + L V + +P GP
Sbjct: 1889 ECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGP 1940
Score = 49.2 bits (112), Expect = 3e-05
Identities = 22/69 (31%), Positives = 39/69 (56%)
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
A + G P P + W K G KL N+++Y + + ++RI + R+ + KY + A N +G
Sbjct: 2509 AKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 2568
Query: 1654 SSVEVTLKV 1662
++ E+ L V
Sbjct: 2569 ANAELELTV 2577
Score = 46.8 bits (106), Expect = 2e-04
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
+ Q P TIS + K DE+ + G P P V WYK ++ D++ ++ T
Sbjct: 1404 VGQAPQFTISPQS-KIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTST 1462
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+S++ +K + + + IE N G +S + +++KP+
Sbjct: 1463 SSILNLKSQEENGTFNCLIE--NELGQASASCQVTIFNKPA 1501
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 1481 SPTVEKPLKNITTEPNEDIE-LTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXX 1534
+P+V+K L++I + I L+C GVP PKV WY+D K+L Y E
Sbjct: 426 APSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAE 485
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
Y C A ND G + T + ++
Sbjct: 486 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVK 519
Score = 42.3 bits (95), Expect = 0.004
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
++G+P P+V WYK+ +L +Y+ E + + +K + S + KYT A+N G+
Sbjct: 451 VDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATNDLGSI 510
Query: 1655 SVEVTLKV 1662
L V
Sbjct: 511 MTHAKLSV 518
Score = 42.3 bits (95), Expect = 0.004
Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1564 VVG--IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
VVG IQ+ PV+T D G+ L+ ++G P P + WY +G + +
Sbjct: 980 VVGGEIQRPPVVTRPLADATVTE--GNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRT 1037
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
+ + ++I E H+ +Y + SN G + V + P E
Sbjct: 1038 YFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETR-AIVVVEAPDAAE 1085
Score = 40.7 bits (91), Expect = 0.011
Identities = 40/208 (19%), Positives = 79/208 (37%), Gaps = 14/208 (6%)
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--- 1529
VI+E P L++ + E L +P+P V WY +G+ + + Y
Sbjct: 548 VIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRK 607
Query: 1530 --ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVITISNEDIKQ 1582
+ R +K + N GE E+ + + Q P D+K
Sbjct: 608 HDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKC 667
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHS 1640
D + I+ P PE+ W++N +++E+ + + + + + + I + S
Sbjct: 668 SES--DILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDS 725
Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
+Y A N G + +++ + SK
Sbjct: 726 GEYKCVAKNKIGKAHTVCCVRIEELLSK 753
Score = 35.5 bits (78), Expect = 0.42
Identities = 37/182 (20%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-----XYKC 1550
NE + + C P + W R+ +L Y Y C
Sbjct: 2295 NESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYAC 2354
Query: 1551 IAFNDHGEVETSC---VVGIQQKPVITISN----EDIKQKHKVGDEW---LVTAVIEGIP 1600
A N+ G T+ V G+ I E IK KV D L +++
Sbjct: 2355 EAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 2414
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
P ++ W +N + + ++ + E + I ++ +YT+EA N +G + + L
Sbjct: 2415 PLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQL 2474
Query: 1661 KV 1662
V
Sbjct: 2475 DV 2476
Score = 34.7 bits (76), Expect = 0.73
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 5/91 (5%)
Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLEN 1364
TL D P P +W + K + S ++ A LT+K + +DAG Y R N
Sbjct: 446 TLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATN 505
Query: 1365 NCG----HADVEMNVTILDKPSPPGKPNILE 1391
+ G HA + + K P ++E
Sbjct: 506 DLGSIMTHAKLSVKADEKKKKKSKTSPAVIE 536
Score = 31.5 bits (68), Expect = 6.8
Identities = 20/87 (22%), Positives = 32/87 (36%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P P+V W K G LE +Y+I + + + Y A+N G +
Sbjct: 2191 ISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIIT 2250
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES 1682
+ V V R+ +E+
Sbjct: 2251 CTSEIDVLPNKEDSAAQVAKRKSRKEA 2277
Score = 31.1 bits (67), Expect = 9.0
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 1906 TVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
T KGK+WTK VT + + N+ + FR+ A+NT G S P++ + + K+ +
Sbjct: 3 TEKGKTWTKAEVTKQAFI---TLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVS 59
Score = 31.1 bits (67), Expect = 9.0
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 1014 ETIPEFIRKLQDFEVKEKD-VAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
+ P ++L+D D +A L +++ + V W +D + + KYD +
Sbjct: 424 DAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGL 483
Query: 1072 RKLYIRNTSVHDEGEYSC 1089
+L ++N D G+Y+C
Sbjct: 484 AELTVKNIVESDAGKYTC 501
>AY130758-4|AAN61520.1| 2708|Caenorhabditis elegans 301KDa_1 protein
protein.
Length = 2708
Score = 140 bits (340), Expect = 8e-33
Identities = 121/465 (26%), Positives = 198/465 (42%), Gaps = 30/465 (6%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K ++ + P F+E L T +G+ + EC V G P P ITW++ + Y
Sbjct: 869 KEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQY 928
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAG--FASSTTELIVEAPLSDHGSEMTVXXXX 617
D V+ L I V D G +TC A N+ G F T + +V+ LS + +T
Sbjct: 929 TDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK-VVDMGLSK--TRLTPVRSR 985
Query: 618 XXXXXXXXADILEGI--PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675
+ + I PP ++ V EG+ LLE + P P I W G+ +
Sbjct: 986 SRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVA 1045
Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---- 731
+ + + + LKI + G Y N+ G ++ ++ +
Sbjct: 1046 ESRTLRTYFDGRV----AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEH 1101
Query: 732 -KEPPQVIEPLKSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-- 787
+ P ++ L+ ++++ GE+ + Q NP + W N K ++ TKS+ T
Sbjct: 1102 VTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQ--QTKSNYKTRLF 1159
Query: 788 --SITILKPKKVKDE--GVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQ- 840
+ L + V DE G YT A N G TSA +T+ E + A P FI +
Sbjct: 1160 DDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKP 1219
Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
+I V E T+ + A + +P+P + W ++N + S+ I DG N +L++ +V E D
Sbjct: 1220 KINVVEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLE-D 1278
Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGK 944
G Y A N GK V++ K V K +K + +EGK
Sbjct: 1279 EGTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGK 1323
Score = 138 bits (334), Expect = 4e-32
Identities = 226/1028 (21%), Positives = 398/1028 (38%), Gaps = 137/1028 (13%)
Query: 473 YLMDENNYTQYLQKKLNE----KIDKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPD-GST 526
Y E + QY+ K N+ + + V E P + E + P FV+KL+ G T
Sbjct: 1064 YEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGET 1123
Query: 527 VQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
F CQ P Q+ W A+ + +++ DDN ATLVI V E GT+T VA
Sbjct: 1124 ATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVA 1183
Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
N G ++ +L + GSE I+E KPK V
Sbjct: 1184 NNQFGDVHTSAQLTIS------GSEAKKIAASLPYF------IIE-------LKPKINVV 1224
Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG+ + ++ L P P++ WL E+V + I + + + L + +V E
Sbjct: 1225 -EGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQ----LLVRDVGLEDE 1279
Query: 706 GTYTVVAVNREGE----ASLPIVLKIKTGEKEPPQVIE--------PLKSMIVRQGESVI 753
GTYT+ A N +G+ + + + EK+ + +E P + + R +
Sbjct: 1280 GTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASK 1339
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITI-LKPKKVKDEGVYTLKAE 808
+ P+ + + + P + + G T S+ + +K E ++ + +
Sbjct: 1340 TEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGK 1399
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N +G+ E S + + + P I+ +I ++ + P PS+ WY+
Sbjct: 1400 NKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK 1459
Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
N I P E I + I N+ S+ ++G + C+ N G++S +VTI +
Sbjct: 1460 ENLQIVPDEKIDVATTSTSS---ILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPA 1516
Query: 929 TF------------VKHLQKSYETEE---GKTVILECQ-TSHTVST-KWYHNKKEISGMD 971
+ V LQK+ E G+ ++L C+ +S + ST W+ + + I
Sbjct: 1517 SLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAG 1576
Query: 972 HREIIQEGRXXXXXX-XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI----PEFIRK 1022
E+ + + D G +C+V ++ E+ + V++ P F
Sbjct: 1577 RYELSSDKKSNHKLVCHAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSAT 1636
Query: 1023 LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
L D LE ++ A +V W +DGE I + + KL I
Sbjct: 1637 LSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAES 1696
Query: 1082 HDEGEYSC----ILRDESCTAEVTVVELPPE----IITRLQNQK---------------V 1118
D G Y C + +S ++ V + + +I + ++K V
Sbjct: 1697 DDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEV 1756
Query: 1119 NKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDD-AGE 1175
N+ + T + + V W KDG EI +N I + G + I +C + +G
Sbjct: 1757 NESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGI 1816
Query: 1176 YSCEVGNSKCTAILTVE------EPSIN-------FTLRLPEFILV---PANTDAYLTVE 1219
+SC+ N T I + +P+ FT+ L + +V P +T
Sbjct: 1817 FSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGS 1876
Query: 1220 IPDETLDVTWYK----KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA-- 1273
P+ TL+ + K ++ T +T K L + + + Y C+ ++
Sbjct: 1877 -PEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSG 1935
Query: 1274 KSTTKLKVEVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
++TT+ + V E PP+ V ++ + V+ FP P+ W N K
Sbjct: 1936 QATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKK 1995
Query: 1328 IKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD---KPSP 1383
I + K K + S + S L+IK V G+Y + N G + + D K P
Sbjct: 1996 INEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDERRKAEP 2055
Query: 1384 PGKPNILE 1391
P ++LE
Sbjct: 2056 PQFKHVLE 2063
Score = 135 bits (326), Expect = 4e-31
Identities = 139/503 (27%), Positives = 207/503 (41%), Gaps = 46/503 (9%)
Query: 435 EAINLVEGERLYILDTSNQDWWYVQKH--LTEEKGWVPAQYLMDENNYTQYLQ-KKLNEK 491
E I L G + I + D++Y++ H T +KG+ +E T + L K
Sbjct: 2219 EGIILETGNKYSIYNDG--DFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNK 2276
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAII 550
D K S +++ AP F+E L + + ++ EC V YP I W R + +
Sbjct: 2277 EDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRL 2336
Query: 551 KPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
P D + M YD + A+L V P D GT+ C A N G A + L V
Sbjct: 2337 LPQADRYTMSYDGE-CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSG------- 2388
Query: 610 EMTVXXXXXXXXXXXXADILEGIPPTF--SKKPKAQYVDEGSDILLECRLVAIPEP-DIA 666
+ EGIPP F K + V +GS + L LV EP I
Sbjct: 2389 --------------VDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIR 2434
Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
WL IV + S + +M L I +V G YTV A N+ G A + L
Sbjct: 2435 WLRNKVTIVDSPSFSYSRSENMVF----LTIADVFPEDGGEYTVEAKNQSGIARCTMQLD 2490
Query: 727 IKTGEK----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALP 779
++ E+ E P+V + + G SV L A+V+G+P P I+W K + + +
Sbjct: 2491 VRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYM 2550
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
+++GD + I + D G Y L A N G A +TV + T+ P F
Sbjct: 2551 MRNEGDKFILRIANVTRA-DAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESP 2609
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSE 898
+ EK +L A + P P+ W Y NE+I + T N L+I +VD +
Sbjct: 2610 ISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKK 2669
Query: 899 IDSGDYKCVASNSAGKSSHGARV 921
G+Y C N G+ A +
Sbjct: 2670 -HFGEYLCTIRNQNGEELANAMI 2691
Score = 129 bits (312), Expect = 2e-29
Identities = 133/630 (21%), Positives = 248/630 (39%), Gaps = 73/630 (11%)
Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
++ PP + L + V +GN+ E+E+ + W+ DG + S ++ DG+
Sbjct: 1000 IQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVA 1059
Query: 1162 KLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSI--------NFTLRLPEFILVP 1209
LKIY+ + G+Y C+V N + AI+ VE P F +L + +L
Sbjct: 1060 FLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 1119
Query: 1210 ANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKF--TLISDVKKRTLIIRKCTEDDQCEY 1266
A A T + + V W ++ T+ T + D TL+I T++ Y
Sbjct: 1120 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 1179
Query: 1267 TCVLL----DAKSTTKLKVEVVE-------FPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
T V D ++ +L + E P I++ + + + G+ +++ D P
Sbjct: 1180 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 1239
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEM 1373
P W+ ++ + + + D + L ++ V D G Y + EN G + E+
Sbjct: 1240 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 1299
Query: 1374 NVT----ILDK------------PSPPGKPNILEIDSSS----INICWDEP-ENTGNSTI 1412
+VT + +K PG+P + +S + + +D P E +S
Sbjct: 1300 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADS-- 1357
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
Y VE + D EW+S + + I+ L N+ Y FR N+ + + SE T K
Sbjct: 1358 --YEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLK 1415
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYE 1530
+ T+ P I +++ E+ F G P P V WY++ ++ +
Sbjct: 1416 TASVGQAPQFTI-SPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVAT 1474
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---------------VITI 1575
+ C+ N+ G+ SC V I KP V T+
Sbjct: 1475 TSTSSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTL 1534
Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634
+ + G + ++T I V W+K+ ++E+ Y +++ +K++ +
Sbjct: 1535 QKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHA 1594
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
++ + KY +N G + E + V D
Sbjct: 1595 VQSQDTGKYRCVVTNKYGYAESECNVAVED 1624
Score = 128 bits (310), Expect = 3e-29
Identities = 180/773 (23%), Positives = 292/773 (37%), Gaps = 104/773 (13%)
Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543
++KK + K K+ V E E M P F L+ G P P + W
Sbjct: 550 IEKKKDRKTSKVVVIE----EMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDW 605
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ I + + D L I V D G + V KNA G S +L V P
Sbjct: 606 YHNGEHISINDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIP 665
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP 663
+ P+F K+ E + LE + A P P
Sbjct: 666 DGQYA-------------------------PSFGKQLSDVKCSESDILKLEVNIQANPAP 700
Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+I W EI ++ + + Y L I + G Y VA N+ G+A
Sbjct: 701 EINWFRNESEIEHSQHHRLQFDDGSGNYS--LTIIDAYAEDSGEYKCVAKNKIGKAHTVC 758
Query: 724 VLKIKT----------GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
++I+ G K P ++ V QG + L V G P P I W K++K
Sbjct: 759 CVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDK 818
Query: 774 PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
P+ + + T+ + + D+G Y +AEN G+A++ +V+ ++E +++
Sbjct: 819 PIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVR 878
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE-----N 887
P F+ + E + L VT P+P+ITWY++ + + Q D + N
Sbjct: 879 PKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLN 938
Query: 888 IELVITNVDSE--------------------IDSGDYKC----VASNSAGKSSHGARVTI 923
I V+ N D E +D G K V S S +S + V
Sbjct: 939 IMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGG 998
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRX 981
++++ V EG +LE + T + +WYH+ K ++ +GR
Sbjct: 999 EIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRV 1058
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET--------IPEFIRKLQDFEVK 1029
G C V ++ ET ++VV+ +P F++KLQD +K
Sbjct: 1059 AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK 1118
Query: 1030 EK-DVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEK-RGHIRKLYIRNTSVHDEGE 1086
+ A + + A VVW +G+ ++ K+ Y + L I N + G
Sbjct: 1119 TAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 1178
Query: 1087 YSCILR----DESCTAEVTV--------VELPPEIITRLQNQKVNKGNKATFEIELT-KG 1133
Y+ + D +A++T+ P I L+ K+N AT I+ G
Sbjct: 1179 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELK-PKINVVEGATLSIQADLNG 1237
Query: 1134 DAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
+ V W KD SE+ S+ IQ+ DG +L + D L+D G Y+ N K
Sbjct: 1238 SPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEK 1290
Score = 123 bits (297), Expect = 1e-27
Identities = 121/517 (23%), Positives = 219/517 (42%), Gaps = 39/517 (7%)
Query: 510 PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F+ K +P+ + +++ + + G P PQ+ W ++ I++ + +Y D D L
Sbjct: 2182 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGD-FYYL 2240
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
+ V D G + C A N G + T+E+ V D +++ ++
Sbjct: 2241 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 2300
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESD 687
L G ++Q + + +EC + A P I W ++P + +++ + +
Sbjct: 2301 LPG---------RSQ-ANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGE 2350
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL----KS 743
C+ LK +V EGTY AVN G A + L++ + + I PL K
Sbjct: 2351 ----CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKI 2406
Query: 744 MIVRQ---GESVILSAQVVGNPRP-TITWCKNNKPVKALPTKSDGDTHSITILKPKKV-- 797
VR+ G V L+A++V P I W +N + P+ S + ++ L V
Sbjct: 2407 KSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFP 2466
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARV 856
+D G YT++A+N GIA + + V A+ + F+ T + G +++L A+V
Sbjct: 2467 EDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKV 2526
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
+P P I+W + + ++ E +G+ L I NV + D+G Y+ A N +G+++
Sbjct: 2527 IGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANV-TRADAGKYELTAINPSGQAN 2585
Query: 917 HGARVTIDVEKVTFVKHLQK------SYETEEGKTVILECQTSHT--VSTKWYHNKKE-I 967
+T+ V+ V K S +T E L S T + +W++N E I
Sbjct: 2586 AELELTV-VQSTKTVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI 2644
Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
G+D I G C +++Q
Sbjct: 2645 DGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTIRNQ 2681
Score = 108 bits (259), Expect = 5e-23
Identities = 114/496 (22%), Positives = 201/496 (40%), Gaps = 42/496 (8%)
Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ-FECQVEGYPRPQITWFRQTA-IIKPSQ 554
VFE+ + + AP ++L G + C V+G P P++ W++ + PS
Sbjct: 429 VFERNIAFDTDAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSM 488
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614
+ +Y++ +A L ++ + DAG +TC A N G + +L V+A T
Sbjct: 489 KYDSFYNE-GLAELTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSP 547
Query: 615 XXXXXXXXXXXADI-----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
+ + + +PP F + G +L +PEP + W
Sbjct: 548 AVIEKKKDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYH 607
Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
GE I +++ + + D Y L I +V EG + V N GE L +
Sbjct: 608 NGEHISINDS-NYLRKHDKGRY--ELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVI 664
Query: 730 GEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSD 783
+ + P + L + + + + L + NP P I W +N ++ L
Sbjct: 665 PDGQYAPSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDG 724
Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE------ENAEPPLFIN 837
+S+TI+ +D G Y A+N G A T + +EE + ++ P F
Sbjct: 725 SGNYSLTII-DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRF-- 781
Query: 838 RFQEITVKE--KGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
R Q T +E +G + LV V+ P P+I W ++++ I S ++ +G +I
Sbjct: 782 RMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGA 841
Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-------ETEEGKTVI 947
D D G Y C A N G + + +++++ H++ + T EG ++
Sbjct: 842 RDD--DQGRYVCEAENIHGVAQSFS--VVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMV 897
Query: 948 LE-CQTSHTVST-KWY 961
LE C T + T WY
Sbjct: 898 LECCVTGKPIPTITWY 913
Score = 108 bits (259), Expect = 5e-23
Identities = 124/516 (24%), Positives = 206/516 (39%), Gaps = 72/516 (13%)
Query: 638 KKPKAQYVDEGSDIL--LECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSV 694
KK V D++ L C + +P P + W +E+ VP S+ +S + +
Sbjct: 445 KKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVP----SMKYDSFYNEGLAE 500
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE------KEPPQVIEPLKS----- 743
L + N+ + G YT A N G L +K E K P VIE K
Sbjct: 501 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSK 560
Query: 744 -MIVRQ-------------------GESVILSAQVVGNPRPTITWCKNNKPVKALPT--- 780
+++ + GE IL P PT+ W N + + +
Sbjct: 561 VVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYL 620
Query: 781 -KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
K D + + IL DEG + +N+ G E+ A +TV P + A P F +
Sbjct: 621 RKHDKGRYELHILSVDST-DEGKWKAVGKNAFGECESEAKLTVVIPDGQYA--PSFGKQL 677
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ E +KL + NP P I W+RN I S+ FD + +T +D+
Sbjct: 678 SDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYA 737
Query: 900 -DSGDYKCVASNSAGKSSHGARVTIDV------EKVT------FVKHLQKSYETEEGKTV 946
DSG+YKCVA N GK+ V I+ +K+ F L E +G +
Sbjct: 738 EDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADL 797
Query: 947 ILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD- 1003
L C S T + KW + K I M ++++ E D G C ++
Sbjct: 798 TLVCSVSGTPHPNIKWTKDDKPID-MSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENI 856
Query: 1004 ---QETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
++ +++ +KE + P+F+ L + E + +LE + + + W +DG
Sbjct: 857 HGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDG 916
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
+ + + R + +L I N ++D+GEY+C
Sbjct: 917 LKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTC 952
Score = 93.9 bits (223), Expect = 1e-18
Identities = 155/717 (21%), Positives = 281/717 (39%), Gaps = 84/717 (11%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN-KYDFEKRGHIRKL 1074
P R L D V E + +LEVE++ T + W DG+++ + + F+ R K+
Sbjct: 1004 PVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKI 1063
Query: 1075 YIRNTSVHDE--GEYSCILRDESCTAE---VTVVELP---------PEIITRLQNQKVNK 1120
Y H+E G+Y C + ++ E + VVE P P + +LQ+ +
Sbjct: 1064 Y----EAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 1119
Query: 1121 -GNKATFEIELTKGDAL-VRWFKDGSEIQF--SNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
G ATF + A V W +G +Q SN+ D L I + + G Y
Sbjct: 1120 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 1179
Query: 1177 SC----EVGNSKCTAILTVE-EPSINFTLRLPEFIL-----VPANTDAYLTVEIP---DE 1223
+ + G+ +A LT+ + LP FI+ + A L+++
Sbjct: 1180 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 1239
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+V W K S + ++++ + D L++R +D+ YT + K + EV
Sbjct: 1240 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 1299
Query: 1284 VEFPPKIVDYEREYR----------------IKRGSDVTLLVDY-QAFPQPNDEWIVNSK 1326
K V ++E + + R S + AF P++ + +
Sbjct: 1300 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADSYE 1359
Query: 1327 IIKKCKHTKPSID---SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
+ ++C + + +KS L IK + I+++ +N G + + L S
Sbjct: 1360 VERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLKTASV 1419
Query: 1384 PGKPNILEIDSSSINICWDEP-----ENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQ 1437
P S I D+ E +G T + + E +I E I V T +
Sbjct: 1420 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVA--TTST 1477
Query: 1438 TSIQNLKTNSSY-RFRAYAVNEVDISDAS-ETTEYYKV--IKETKIQS------PTVEKP 1487
+SI NLK+ F NE+ + AS + T + K ++ T S PT++K
Sbjct: 1478 SSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKA 1537
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXX 1542
L N + + + I LTC + V W++D +++++A + ++
Sbjct: 1538 LNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQS 1597
Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ--KPVITISNEDIKQKHKV-GDEWLVTAVIEGI 1599
Y+C+ N +G E+ C V ++ K + + + + G + +EG
Sbjct: 1598 QDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGS 1657
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS 1655
P PEV W K+G ++ + T E + + I + + Y A++ AG S
Sbjct: 1658 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDS 1714
Score = 72.9 bits (171), Expect = 2e-12
Identities = 89/420 (21%), Positives = 167/420 (39%), Gaps = 33/420 (7%)
Query: 1274 KSTTKLKV--EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-K 1330
+ T+K+ V E+++ PP ++ K G L+V P+P +W N + I
Sbjct: 556 RKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISIN 615
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKP 1387
+ D L I V++TD G +K +N G + E +T++ + +P
Sbjct: 616 DSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGK 675
Query: 1388 NILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNL 1443
+ ++ S +I E N + I + EI+ ++ ++ +I +
Sbjct: 676 QLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDA 735
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVI--KETKI---QSPTVEKPLKNITTEPN-E 1497
S ++ A N++ + +++ + KI ++P L P
Sbjct: 736 YAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGA 795
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRX-XXXXXXXXXXXXXXYKCIAFN 1554
D+ L C G P P + W +D K + + + +EN Y C A N
Sbjct: 796 DLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAEN 855
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKV---------GDEWLVTAVIEGIPPPEVI 1605
HG ++ VV I++ + + ++ K G+E ++ + G P P +
Sbjct: 856 IHGVAQSFSVVEIKE----AVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTIT 911
Query: 1606 WYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYK+G KL ++ T ++ S + I + + +YT EA N+ G T+KV D
Sbjct: 912 WYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 971
Score = 72.1 bits (169), Expect = 4e-12
Identities = 102/420 (24%), Positives = 173/420 (41%), Gaps = 44/420 (10%)
Query: 1002 KDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK 1057
KD++TS ++V++E I P F LQD E K + IL V + V W +GE I
Sbjct: 554 KDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHIS 613
Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAE--VTVV----ELPPEI 1109
+ Y + +L+I + DEG++ + ++ C +E +TVV + P
Sbjct: 614 INDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSF 673
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID--GKKQKLKIY 1166
+L + K ++ + E+ + A + WF++ SEI+ S H +L D L I
Sbjct: 674 GKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTII 733
Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEE------------PSINFTLRLPEFILVPA 1210
D +D+GEY C ++G + + +EE + F ++LP VP
Sbjct: 734 DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQ 793
Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
D L + ++ W K I+ + K + + TL I +DDQ Y C
Sbjct: 794 GADLTLVCSVSGTPHPNIKWTKDDKPIDMSNK-QVRHENGVCTLHIIGARDDDQGRYVCE 852
Query: 1270 ------LLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
+ + S ++K V+ PK ++ G+++ L P P W
Sbjct: 853 AENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITW 912
Query: 1322 IVNS-KIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
+ K+I + + + + D K S L I V D G Y N+ G V ++D
Sbjct: 913 YKDGLKLIIENRMLQYT-DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 971
Score = 70.1 bits (164), Expect = 2e-11
Identities = 80/320 (25%), Positives = 121/320 (37%), Gaps = 42/320 (13%)
Query: 1480 QSPTVEKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538
Q PT K L+++ + E TC P +V W +GK L+ K+ Y+ R
Sbjct: 1104 QMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNT 1163
Query: 1539 XXXXXXXXX------YKCIAFNDHGEVETSCVVGIQQKPVITISNE------DIKQKHKV 1586
Y +A N G+V TS + I I+ ++K K V
Sbjct: 1164 ATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINV 1223
Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + A + G P PEV+W K+ ++L + + ++++ YT
Sbjct: 1224 VEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYT 1283
Query: 1645 IEASNTAG----------TSSVEVTLKVYDK-----------PSKPEGPVIMREISRESV 1683
I A N G T S EV K K P +P P E V
Sbjct: 1284 ITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQV 1343
Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
T+ + P +G + Y +E+ PD W+ + +E I+ L N EY+FRV
Sbjct: 1344 TMAFDAP-SEGPAD--SYEVERRCPDQREWVSCGST-KSLELE-IKGLTPNTEYIFRVAG 1398
Query: 1744 QNPVGFSEALESEPIVIKTA 1763
+N G E E +KTA
Sbjct: 1399 KNKQGLGEWSEMTS-TLKTA 1417
Score = 70.1 bits (164), Expect = 2e-11
Identities = 106/437 (24%), Positives = 167/437 (38%), Gaps = 56/437 (12%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F+ K + +V E+ ++ L+ I+ V W+++G II NKY G L
Sbjct: 2182 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG-IILETGNKYSIYNDGDFYYL 2240
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL 1130
+ + S D+G Y+C + +CT+E+ V+ + ++ +K K KA IE+
Sbjct: 2241 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 2300
Query: 1131 TKG------------DALVRWFKDGSEIQFSNHIQL---------TIDGKKQKLKIYDCD 1169
G + V + S I N ++L + DG+ LK
Sbjct: 2301 LPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVT 2360
Query: 1170 LDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFIL---------VPANTDAYL 1216
D G Y+CE N +A+ L V N +P V + L
Sbjct: 2361 PGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVEL 2420
Query: 1217 TVEI--PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272
E+ E L + W + K I D+ F+ L I +D EYT +
Sbjct: 2421 AAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQS 2480
Query: 1273 --AKSTTKLKVE-----VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VN 1324
A+ T +L V V + P++ D+E R G V L P P W
Sbjct: 2481 GIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAG 2540
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K+ + K+ + K L I V DAG Y+L N G A+ E+ +T++
Sbjct: 2541 QKLNNEEKYMMRNEGDKFI-LRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTV 2599
Query: 1385 G-KPNILEIDSSSINIC 1400
G KP E S+ C
Sbjct: 2600 GAKPKFNE-SPISVQTC 2615
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/247 (25%), Positives = 96/247 (38%), Gaps = 20/247 (8%)
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
KT+ + +A N I++ + K + +P PL ++ L+C
Sbjct: 1812 KTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSC 1871
Query: 1504 IFGGVPQPKVTW-YRD--GKKLKTAKAT-------YENRXXXXXXXXXXXXXXXYKCIAF 1553
G P+P + W Y D G K+ +T + Y+CIA
Sbjct: 1872 NVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIAT 1931
Query: 1554 NDHGEVETSC--VVG-IQQKPV----ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
N G+ T C +VG + +P +D K E+ V + G P P++ W
Sbjct: 1932 NSSGQATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVE--LAGFPTPDLTW 1989
Query: 1607 YKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
Y N K+ K+ IT + TSV+ IK + + Y +EASN G L V D+
Sbjct: 1990 YHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDE 2049
Query: 1666 PSKPEGP 1672
K E P
Sbjct: 2050 RRKAEPP 2056
Score = 58.8 bits (136), Expect = 4e-08
Identities = 133/587 (22%), Positives = 225/587 (38%), Gaps = 86/587 (14%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F Q + +D + VE + + T V W ++ I P + K D L
Sbjct: 1423 PQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDE-KIDVATTSTSSIL 1481
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PE------IITRLQNQKV 1118
++ S + G ++C++ +E S + +VT+ P P+ ++ LQ
Sbjct: 1482 NLK--SQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALN 1539
Query: 1119 NKGNKATFEIELT-----KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDD 1172
N+ +A +I LT + ++ V WFKD I+ + +L+ D K KL + D
Sbjct: 1540 NESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQD 1599
Query: 1173 AGEYSCEVGN------SKCT-AILTVEE---PSINFTLRLPEFILVPANTDAYLTVEIPD 1222
G+Y C V N S+C A+ V + PS + TL IL N VE
Sbjct: 1600 TGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAIL-GHNITLECKVE-GS 1657
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTC------------- 1268
+V+W K I T + D L I K DD Y C
Sbjct: 1658 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSS 1717
Query: 1269 VLLDAKST-TKLKVEVVEFPPKIVDYEREYR-------IKRGSDVTLLVDYQAFPQPNDE 1320
+++ AK+T T + + + + + R R + TL+ P+P
Sbjct: 1718 MVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVT 1777
Query: 1321 WIVNSKIIKKCK---HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W+ + + I + H + D +S L + V + +GI+ + EN G E V I
Sbjct: 1778 WLKDGREILRTNRIYHHFVTGDGES-HLIAECVVSKTSGIFSCKAENPNGTVIAETQV-I 1835
Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK------ 1431
+ + P + + + D G+ T + V T EWI +
Sbjct: 1836 VQRMKPANQ--LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKI 1893
Query: 1432 NITKTQTS--------IQNLKTNSSYRFRAYAVNEVDISDASE-TTEYYKVIKETKIQS- 1481
N+T + T + LK+ R + + + + + TT+ Y ++ E +
Sbjct: 1894 NLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPA 1953
Query: 1482 --PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P K L++ T E IE + G P P +TWY + KK+ K
Sbjct: 1954 GPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGK 2000
Score = 56.4 bits (130), Expect = 2e-07
Identities = 71/365 (19%), Positives = 133/365 (36%), Gaps = 27/365 (7%)
Query: 1313 AFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
A+P + W NS +++ + S D + ASL V D G Y N G A
Sbjct: 2321 AYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVT 2380
Query: 1372 EMNVTI--LDKPSPPGKPNILE----------IDSSSINICWDEPENTGNSTIIYYVVEY 1419
MN+ + +D + G P + +D S + + + + + I + +
Sbjct: 2381 NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKV 2440
Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
+D+ + ++ +I ++ + A N+ I+ + + +
Sbjct: 2441 TIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVAD 2500
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXX 1535
++P V ++P +EL G P P ++W + G+KL K ++
Sbjct: 2501 EAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFIL 2560
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-------KPVITISNEDIKQKHKVGD 1588
Y+ A N G+ + + Q KP S ++ K
Sbjct: 2561 RIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRA 2620
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
E + A G P P W+ NGN+L + + Y IT+ + S + I + + H +Y
Sbjct: 2621 E--LRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTI 2678
Query: 1648 SNTAG 1652
N G
Sbjct: 2679 RNQNG 2683
Score = 56.0 bits (129), Expect = 3e-07
Identities = 85/380 (22%), Positives = 153/380 (40%), Gaps = 40/380 (10%)
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA------ 1098
A ++W R+ + P+ ++Y G L + + DEG Y+C +E +A
Sbjct: 2325 ASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVTNMNL 2384
Query: 1099 EVTVVE------LPPEI-ITRLQN-QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQF 1148
+V+ V+ +PP ++++ +KV G++ EL + +RW ++ I
Sbjct: 2385 QVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVD 2444
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPE 1204
S + L I D +D GEY+ E N ++CT L V + P
Sbjct: 2445 SPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPR 2504
Query: 1205 -FILVP-ANTDAYLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
F P +D ++VE+ + + ++W K + + EK+ + ++ K L I
Sbjct: 2505 VFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIAN 2564
Query: 1258 CTEDDQCEY--TCVLLDAKSTTKLKVEVVE------FPPKIVDYEREYRIKRGSDVTLLV 1309
T D +Y T + ++ +L++ VV+ PK + + + L
Sbjct: 2565 VTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRAELRA 2624
Query: 1310 DYQAFPQPNDEWIVN-SKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P W N +++I +T S D+ S SL I V+ G Y + N G
Sbjct: 2625 SFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNS-SLLINSVDKKHFGEYLCTIRNQNG 2683
Query: 1368 HADVEMNVTILDKPSPPGKP 1387
+ N IL + S P
Sbjct: 2684 --EELANAMILSEGSSAALP 2701
Score = 54.8 bits (126), Expect = 6e-07
Identities = 165/857 (19%), Positives = 306/857 (35%), Gaps = 104/857 (12%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF------RQTAIIKPS 553
KP ++ ++AP F L +G C V G P P + W + + +
Sbjct: 1840 KPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSST 1899
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
D+ VA L V E GT+ C+A N++G A++ L+V LSD +
Sbjct: 1900 TDWTECRFG-KVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLV-GELSDEPAGPPR 1957
Query: 614 XXXXXXXXXXXXADILE------GIP-PTFSKKPKAQYVDEGSDILLE-----CRLVAIP 661
+ +E G P P + + ++EG D+ + +++I
Sbjct: 1958 FVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIK 2017
Query: 662 EPDIAWLFKGEEIVPDENISVAIE-------SDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
+A L G V NI + SD + +V + VA +
Sbjct: 2018 NVSLASL--GMYFVEASNIHGVLRTAGRLNVSDERRKAEPPQFKHVLEPVLAVQPKVAFS 2075
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-NK 773
E + + + P ++ L+ M ++ G S ++ ++ RP + + +K
Sbjct: 2076 EEHPRASSSAATARVKKGAAPMFLQGLEDMDLKAGASAAVAGKLGRKLRPHRSTTNDADK 2135
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
KAL S+ + +P+ D + E++ A + + P
Sbjct: 2136 LAKAL-------AQSLRLDEPRASIDS-----RPESAANAALDEVRAAINSRNKRVCRPK 2183
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
+ ++E +++L ++ NP+P + W + I+ + DG+ L +
Sbjct: 2184 FMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVH 2243
Query: 894 NVDSEIDSGDYKCVASNSAG-------------KSSHGARVT-----IDVEKVTFVKHLQ 935
+V S D G Y C A+N+ G K A+V + + F++ L
Sbjct: 2244 HV-STFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLP 2302
Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXX 992
+ +++ +EC S S W N + + D + +G
Sbjct: 2303 GRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG 2362
Query: 993 DVGVIKCIVKDQ----ETSTMLVVKETIP---EFIRKLQDFE-VK--EKDVAILEVEI-- 1040
D G C ++ T+ L V P E I L FE +K K V VE+
Sbjct: 2363 DEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAA 2422
Query: 1041 ----NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES- 1095
SE + W R+ I + + + + ++ L I + D GEY+ +++S
Sbjct: 2423 ELVQASEPLQIRWLRNKVTIVDSPS-FSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSG 2481
Query: 1096 ---CTAEV-------TVVELPPEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGS 1144
CT ++ +V + P + + + G + + D ++ W K G
Sbjct: 2482 IARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQ 2541
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-- 1202
++ + +G K L+I + DAG+Y N A +E + T +
Sbjct: 2542 KLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGA 2601
Query: 1203 -PEFILVPANTD------AYLTVEIPDETLDV-TW-YKKKSVIEDTEKFTLISDVKKRTL 1253
P+F P + A L W Y +I+ + +T+ S +L
Sbjct: 2602 KPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSL 2661
Query: 1254 IIRKCTEDDQCEYTCVL 1270
+I + EY C +
Sbjct: 2662 LINSVDKKHFGEYLCTI 2678
Score = 54.0 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 79/204 (38%), Gaps = 20/204 (9%)
Query: 1482 PTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGK---KLKTAKATYENR-XXXX 1536
P V +PL + T TE N ++ L G P P + WY DGK + +T + ++ R
Sbjct: 1004 PVVTRPLADATVTEGNREL-LEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLK 1062
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ---------QKPVITISNEDIKQKHKVG 1587
Y C N G VET +V ++ Q P +D+ K G
Sbjct: 1063 IYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK-TAG 1121
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK---EKTSVIRIKELKRSHSSKYT 1644
+ T P +V+W NG L+ K N T+ + T+ + I+ + YT
Sbjct: 1122 ETATFTCQSYANPAAQVVWLHNGKALQQTKS-NYKTRLFDDNTATLVIENVTDELCGTYT 1180
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSK 1668
A+N G L + +K
Sbjct: 1181 AVANNQFGDVHTSAQLTISGSEAK 1204
Score = 53.2 bits (122), Expect = 2e-06
Identities = 89/412 (21%), Positives = 155/412 (37%), Gaps = 43/412 (10%)
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKL 1360
G + L + + W + + I+ + S D KS L V++ D G Y+
Sbjct: 1546 GQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRC 1605
Query: 1361 RLENNCGHADVEMNVTILD--KPSPPGKPNILEIDSSSI---NICWDEPENTGNSTIIYY 1415
+ N G+A+ E NV + D K P L DS++I NI + + + +
Sbjct: 1606 VVTNKYGYAESECNVAVEDVTKFIAPSFSATLS-DSTAILGHNITLECKVEGSPAPEVSW 1664
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
+ + I TT I + K S Y + ++ T+ + K
Sbjct: 1665 TKDGERISTTRRIRQTQDENGNCKLSISKAESD-DMGVYVCSATSVAGVDSTSSMVMIAK 1723
Query: 1476 ETKIQSPTV---------EKP----LKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGK 1520
T S V EKP E NE + T I V P+P VTW +DG+
Sbjct: 1724 TTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGR 1783
Query: 1521 K-LKTAK-----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVI 1573
+ L+T + T + + C A N +G V V +Q+ KP
Sbjct: 1784 EILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPAN 1843
Query: 1574 TISNEDIKQKHKVGDEWLV-------TAVIEGIPPPEVIWY---KNGNKL---ENDKEYN 1620
++N K + D +V + + G P P + W +G+K+ + ++
Sbjct: 1844 QLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWT 1903
Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
K + ++ + + R Y A+N++G ++ + L V + +P GP
Sbjct: 1904 ECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGP 1955
Score = 49.2 bits (112), Expect = 3e-05
Identities = 22/69 (31%), Positives = 39/69 (56%)
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
A + G P P + W K G KL N+++Y + + ++RI + R+ + KY + A N +G
Sbjct: 2524 AKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 2583
Query: 1654 SSVEVTLKV 1662
++ E+ L V
Sbjct: 2584 ANAELELTV 2592
Score = 46.8 bits (106), Expect = 2e-04
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
+ Q P TIS + K DE+ + G P P V WYK ++ D++ ++ T
Sbjct: 1419 VGQAPQFTISPQS-KIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTST 1477
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+S++ +K + + + IE N G +S + +++KP+
Sbjct: 1478 SSILNLKSQEENGTFNCLIE--NELGQASASCQVTIFNKPA 1516
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 1481 SPTVEKPLKNITTEPNEDIE-LTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXX 1534
+P+V+K L++I + I L+C GVP PKV WY+D K+L Y E
Sbjct: 441 APSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAE 500
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
Y C A ND G + T + ++
Sbjct: 501 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVK 534
Score = 42.3 bits (95), Expect = 0.004
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
++G+P P+V WYK+ +L +Y+ E + + +K + S + KYT A+N G+
Sbjct: 466 VDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATNDLGSI 525
Query: 1655 SVEVTLKV 1662
L V
Sbjct: 526 MTHAKLSV 533
Score = 42.3 bits (95), Expect = 0.004
Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1564 VVG--IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
VVG IQ+ PV+T D G+ L+ ++G P P + WY +G + +
Sbjct: 995 VVGGEIQRPPVVTRPLADATVTE--GNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRT 1052
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
+ + ++I E H+ +Y + SN G + V + P E
Sbjct: 1053 YFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETR-AIVVVEAPDAAE 1100
Score = 40.7 bits (91), Expect = 0.011
Identities = 40/208 (19%), Positives = 79/208 (37%), Gaps = 14/208 (6%)
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--- 1529
VI+E P L++ + E L +P+P V WY +G+ + + Y
Sbjct: 563 VIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRK 622
Query: 1530 --ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVITISNEDIKQ 1582
+ R +K + N GE E+ + + Q P D+K
Sbjct: 623 HDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKC 682
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHS 1640
D + I+ P PE+ W++N +++E+ + + + + + + I + S
Sbjct: 683 SES--DILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDS 740
Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
+Y A N G + +++ + SK
Sbjct: 741 GEYKCVAKNKIGKAHTVCCVRIEELLSK 768
Score = 35.5 bits (78), Expect = 0.42
Identities = 37/182 (20%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-----XYKC 1550
NE + + C P + W R+ +L Y Y C
Sbjct: 2310 NESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYAC 2369
Query: 1551 IAFNDHGEVETSC---VVGIQQKPVITISN----EDIKQKHKVGDEW---LVTAVIEGIP 1600
A N+ G T+ V G+ I E IK KV D L +++
Sbjct: 2370 EAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 2429
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
P ++ W +N + + ++ + E + I ++ +YT+EA N +G + + L
Sbjct: 2430 PLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQL 2489
Query: 1661 KV 1662
V
Sbjct: 2490 DV 2491
Score = 34.7 bits (76), Expect = 0.73
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 5/91 (5%)
Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLEN 1364
TL D P P +W + K + S ++ A LT+K + +DAG Y R N
Sbjct: 461 TLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATN 520
Query: 1365 NCG----HADVEMNVTILDKPSPPGKPNILE 1391
+ G HA + + K P ++E
Sbjct: 521 DLGSIMTHAKLSVKADEKKKKKSKTSPAVIE 551
Score = 31.5 bits (68), Expect = 6.8
Identities = 20/87 (22%), Positives = 32/87 (36%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P P+V W K G LE +Y+I + + + Y A+N G +
Sbjct: 2206 ISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIIT 2265
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES 1682
+ V V R+ +E+
Sbjct: 2266 CTSEIDVLPNKEDSAAQVAKRKSRKEA 2292
Score = 31.1 bits (67), Expect = 9.0
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 1906 TVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
T KGK+WTK VT + + N+ + FR+ A+NT G S P++ + + K+ +
Sbjct: 3 TEKGKTWTKAEVTKQAFI---TLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVS 59
Score = 31.1 bits (67), Expect = 9.0
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 1014 ETIPEFIRKLQDFEVKEKD-VAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
+ P ++L+D D +A L +++ + V W +D + + KYD +
Sbjct: 439 DAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGL 498
Query: 1072 RKLYIRNTSVHDEGEYSC 1089
+L ++N D G+Y+C
Sbjct: 499 AELTVKNIVESDAGKYTC 516
>AY130758-2|AAN61518.1| 18519|Caenorhabditis elegans 2MDa_2 protein
protein.
Length = 18519
Score = 140 bits (340), Expect = 8e-33
Identities = 121/465 (26%), Positives = 198/465 (42%), Gaps = 30/465 (6%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K ++ + P F+E L T +G+ + EC V G P P ITW++ + Y
Sbjct: 16680 KEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQY 16739
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAG--FASSTTELIVEAPLSDHGSEMTVXXXX 617
D V+ L I V D G +TC A N+ G F T + +V+ LS + +T
Sbjct: 16740 TDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK-VVDMGLSK--TRLTPVRSR 16796
Query: 618 XXXXXXXXADILEGI--PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675
+ + I PP ++ V EG+ LLE + P P I W G+ +
Sbjct: 16797 SRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVA 16856
Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---- 731
+ + + + LKI + G Y N+ G ++ ++ +
Sbjct: 16857 ESRTLRTYFDGRV----AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEH 16912
Query: 732 -KEPPQVIEPLKSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-- 787
+ P ++ L+ ++++ GE+ + Q NP + W N K ++ TKS+ T
Sbjct: 16913 VTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQ--QTKSNYKTRLF 16970
Query: 788 --SITILKPKKVKDE--GVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQ- 840
+ L + V DE G YT A N G TSA +T+ E + A P FI +
Sbjct: 16971 DDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKP 17030
Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
+I V E T+ + A + +P+P + W ++N + S+ I DG N +L++ +V E D
Sbjct: 17031 KINVVEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLE-D 17089
Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGK 944
G Y A N GK V++ K V K +K + +EGK
Sbjct: 17090 EGTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGK 17134
Score = 138 bits (335), Expect = 3e-32
Identities = 109/480 (22%), Positives = 205/480 (42%), Gaps = 17/480 (3%)
Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNK 1062
+ T ++V+ + P ++ ++ ++ +K LE A + +W +DG+ I P
Sbjct: 14438 EPTIPVVVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDEN 14497
Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELPPEIITRLQN-QK 1117
+ G + L I + D G Y ++ + TAE V + ++ + +
Sbjct: 14498 TEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELTE 14557
Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
+ +G+ E++ +A+V W+KDG ++ S+ +Q +K+ L+I D+G Y
Sbjct: 14558 IEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADSGVYK 14617
Query: 1178 CEV--GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235
CE G S+ + V E + + + I+ L E V W+K
Sbjct: 14618 CETTDGRSRTEGEVIVNEQEPHILVGPQDAIVKDFGETMVLFCETSKPVRKVKWFKNGVE 14677
Query: 1236 I-EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV--- 1291
I K + +D K+ TL I+ + D YT + + +++ K+ V E P ++
Sbjct: 14678 IWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEKETSAPAKL-VFEVAPNLIIPT 14736
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
+ + G++ V++ FP P N +K DS S+ +K V
Sbjct: 14737 EIRDGVTVHAGNEFDFAVEFSGFPIPTIHLTNNGTPLKAIAVVTEYDDS--VSVRMKDVT 14794
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
++G ++ E+ G E+ + I+DKPS P E+ S+ + W P T +
Sbjct: 14795 LDNSGTVRVIAESPLGQCIKEIPLKIIDKPSAPCDLQFKEVTEDSVFLSWQPPLETNGAP 14854
Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTE 1469
+ YV+E + +D W + T+ + ++L N Y FR AVNEV S+ +T +
Sbjct: 14855 LTGYVIERKAVDNNRWRPCGQVKPTKLTFVAEDLFCNQVYGFRILAVNEVGESEPCDTVD 14914
Score = 138 bits (334), Expect = 4e-32
Identities = 226/1028 (21%), Positives = 398/1028 (38%), Gaps = 137/1028 (13%)
Query: 473 YLMDENNYTQYLQKKLNE----KIDKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPD-GST 526
Y E + QY+ K N+ + + V E P + E + P FV+KL+ G T
Sbjct: 16875 YEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGET 16934
Query: 527 VQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
F CQ P Q+ W A+ + +++ DDN ATLVI V E GT+T VA
Sbjct: 16935 ATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVA 16994
Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
N G ++ +L + GSE I+E KPK V
Sbjct: 16995 NNQFGDVHTSAQLTIS------GSEAKKIAASLPYF------IIE-------LKPKINVV 17035
Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG+ + ++ L P P++ WL E+V + I + + + L + +V E
Sbjct: 17036 -EGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQ----LLVRDVGLEDE 17090
Query: 706 GTYTVVAVNREGE----ASLPIVLKIKTGEKEPPQVIE--------PLKSMIVRQGESVI 753
GTYT+ A N +G+ + + + EK+ + +E P + + R +
Sbjct: 17091 GTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASK 17150
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITI-LKPKKVKDEGVYTLKAE 808
+ P+ + + + P + + G T S+ + +K E ++ + +
Sbjct: 17151 TEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGK 17210
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N +G+ E S + + + P I+ +I ++ + P PS+ WY+
Sbjct: 17211 NKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK 17270
Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
N I P E I + I N+ S+ ++G + C+ N G++S +VTI +
Sbjct: 17271 ENLQIVPDEKIDVATTSTSS---ILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPA 17327
Query: 929 TF------------VKHLQKSYETEE---GKTVILECQ-TSHTVST-KWYHNKKEISGMD 971
+ V LQK+ E G+ ++L C+ +S + ST W+ + + I
Sbjct: 17328 SLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAG 17387
Query: 972 HREIIQEGRXXXXXX-XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI----PEFIRK 1022
E+ + + D G +C+V ++ E+ + V++ P F
Sbjct: 17388 RYELSSDKKSNHKLVCHAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSAT 17447
Query: 1023 LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
L D LE ++ A +V W +DGE I + + KL I
Sbjct: 17448 LSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAES 17507
Query: 1082 HDEGEYSC----ILRDESCTAEVTVVELPPE----IITRLQNQK---------------V 1118
D G Y C + +S ++ V + + +I + ++K V
Sbjct: 17508 DDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEV 17567
Query: 1119 NKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDD-AGE 1175
N+ + T + + V W KDG EI +N I + G + I +C + +G
Sbjct: 17568 NESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGI 17627
Query: 1176 YSCEVGNSKCTAILTVE------EPSIN-------FTLRLPEFILV---PANTDAYLTVE 1219
+SC+ N T I + +P+ FT+ L + +V P +T
Sbjct: 17628 FSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGS 17687
Query: 1220 IPDETLDVTWYK----KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA-- 1273
P+ TL+ + K ++ T +T K L + + + Y C+ ++
Sbjct: 17688 -PEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSG 17746
Query: 1274 KSTTKLKVEVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
++TT+ + V E PP+ V ++ + V+ FP P+ W N K
Sbjct: 17747 QATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKK 17806
Query: 1328 IKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD---KPSP 1383
I + K K + S + S L+IK V G+Y + N G + + D K P
Sbjct: 17807 INEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDERRKAEP 17866
Query: 1384 PGKPNILE 1391
P ++LE
Sbjct: 17867 PQFKHVLE 17874
Score = 135 bits (326), Expect = 4e-31
Identities = 139/503 (27%), Positives = 207/503 (41%), Gaps = 46/503 (9%)
Query: 435 EAINLVEGERLYILDTSNQDWWYVQKH--LTEEKGWVPAQYLMDENNYTQYLQ-KKLNEK 491
E I L G + I + D++Y++ H T +KG+ +E T + L K
Sbjct: 18030 EGIILETGNKYSIYNDG--DFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNK 18087
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAII 550
D K S +++ AP F+E L + + ++ EC V YP I W R + +
Sbjct: 18088 EDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRL 18147
Query: 551 KPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
P D + M YD + A+L V P D GT+ C A N G A + L V
Sbjct: 18148 LPQADRYTMSYDGE-CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSG------- 18199
Query: 610 EMTVXXXXXXXXXXXXADILEGIPPTF--SKKPKAQYVDEGSDILLECRLVAIPEP-DIA 666
+ EGIPP F K + V +GS + L LV EP I
Sbjct: 18200 --------------VDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIR 18245
Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
WL IV + S + +M L I +V G YTV A N+ G A + L
Sbjct: 18246 WLRNKVTIVDSPSFSYSRSENMVF----LTIADVFPEDGGEYTVEAKNQSGIARCTMQLD 18301
Query: 727 IKTGEK----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALP 779
++ E+ E P+V + + G SV L A+V+G+P P I+W K + + +
Sbjct: 18302 VRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYM 18361
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
+++GD + I + D G Y L A N G A +TV + T+ P F
Sbjct: 18362 MRNEGDKFILRIANVTRA-DAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESP 18420
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSE 898
+ EK +L A + P P+ W Y NE+I + T N L+I +VD +
Sbjct: 18421 ISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKK 18480
Query: 899 IDSGDYKCVASNSAGKSSHGARV 921
G+Y C N G+ A +
Sbjct: 18481 -HFGEYLCTIRNQNGEELANAMI 18502
Score = 133 bits (321), Expect = 2e-30
Identities = 100/386 (25%), Positives = 169/386 (43%), Gaps = 17/386 (4%)
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISV-KNITKTQTSIQN 1442
GKP + ++SI + W T ++ + Y V+ +E ++ W V K I++ +I
Sbjct: 15505 GKPEYVSSTATSIALKW-----TSDNDEVTYTVQMKEANSKRPWAVVAKEISECSATIAQ 15559
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
LK +SY FR A N+ + SE +E + T+ + P ++T N ++T
Sbjct: 15560 LKEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTESKKPAFTNAPTDLTAVKNGKTKIT 15619
Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATY-EN---RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
F G P P++ W+++ K++ + K + EN YK + N G
Sbjct: 15620 AEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMREDDEGEYKIVVKNTAGS 15679
Query: 1559 VETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY-KNGNKLEND 1616
VE SC + + Q P I + G+ + G P PEVIW NG +E
Sbjct: 15680 VEHSCKLTMDQLPEINRVDRYASTLVFDKGETVKLRLSFSGRPQPEVIWIDNNGKVIEES 15739
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
++ I +V+ I + ++ ++ N G + ++V D+P+ P P +
Sbjct: 15740 RKMKIEKTVLNTVLTINSIDSQDQGEFALKIKNRCGEDKYAIGIQVTDRPAAPGKPAV-E 15798
Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
+ + +SV + W P +DGG + Y +E W K A+V + + L
Sbjct: 15799 DQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWTK-AEVTKQA-FITLFNLVPGES 15856
Query: 1737 YMFRVIAQNPVGFSE-ALESEPIVIK 1761
Y FRV A N G SE + ESE +V+K
Sbjct: 15857 YRFRVRADNTFGQSEPSDESELVVVK 15882
Score = 129 bits (312), Expect = 2e-29
Identities = 133/630 (21%), Positives = 248/630 (39%), Gaps = 73/630 (11%)
Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
++ PP + L + V +GN+ E+E+ + W+ DG + S ++ DG+
Sbjct: 16811 IQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVA 16870
Query: 1162 KLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSI--------NFTLRLPEFILVP 1209
LKIY+ + G+Y C+V N + AI+ VE P F +L + +L
Sbjct: 16871 FLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 16930
Query: 1210 ANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKF--TLISDVKKRTLIIRKCTEDDQCEY 1266
A A T + + V W ++ T+ T + D TL+I T++ Y
Sbjct: 16931 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 16990
Query: 1267 TCVLL----DAKSTTKLKVEVVE-------FPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
T V D ++ +L + E P I++ + + + G+ +++ D P
Sbjct: 16991 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 17050
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEM 1373
P W+ ++ + + + D + L ++ V D G Y + EN G + E+
Sbjct: 17051 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 17110
Query: 1374 NVT----ILDK------------PSPPGKPNILEIDSSS----INICWDEP-ENTGNSTI 1412
+VT + +K PG+P + +S + + +D P E +S
Sbjct: 17111 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADS-- 17168
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
Y VE + D EW+S + + I+ L N+ Y FR N+ + + SE T K
Sbjct: 17169 --YEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLK 17226
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYE 1530
+ T+ P I +++ E+ F G P P V WY++ ++ +
Sbjct: 17227 TASVGQAPQFTI-SPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVAT 17285
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---------------VITI 1575
+ C+ N+ G+ SC V I KP V T+
Sbjct: 17286 TSTSSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTL 17345
Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634
+ + G + ++T I V W+K+ ++E+ Y +++ +K++ +
Sbjct: 17346 QKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHA 17405
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
++ + KY +N G + E + V D
Sbjct: 17406 VQSQDTGKYRCVVTNKYGYAESECNVAVED 17435
Score = 128 bits (310), Expect = 3e-29
Identities = 180/773 (23%), Positives = 292/773 (37%), Gaps = 104/773 (13%)
Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543
++KK + K K+ V E E M P F L+ G P P + W
Sbjct: 16361 IEKKKDRKTSKVVVIE----EMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDW 16416
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ I + + D L I V D G + V KNA G S +L V P
Sbjct: 16417 YHNGEHISINDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIP 16476
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP 663
+ P+F K+ E + LE + A P P
Sbjct: 16477 DGQYA-------------------------PSFGKQLSDVKCSESDILKLEVNIQANPAP 16511
Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+I W EI ++ + + Y L I + G Y VA N+ G+A
Sbjct: 16512 EINWFRNESEIEHSQHHRLQFDDGSGNYS--LTIIDAYAEDSGEYKCVAKNKIGKAHTVC 16569
Query: 724 VLKIKT----------GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
++I+ G K P ++ V QG + L V G P P I W K++K
Sbjct: 16570 CVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDK 16629
Query: 774 PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
P+ + + T+ + + D+G Y +AEN G+A++ +V+ ++E +++
Sbjct: 16630 PIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVR 16689
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE-----N 887
P F+ + E + L VT P+P+ITWY++ + + Q D + N
Sbjct: 16690 PKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLN 16749
Query: 888 IELVITNVDSE--------------------IDSGDYKC----VASNSAGKSSHGARVTI 923
I V+ N D E +D G K V S S +S + V
Sbjct: 16750 IMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGG 16809
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRX 981
++++ V EG +LE + T + +WYH+ K ++ +GR
Sbjct: 16810 EIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRV 16869
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET--------IPEFIRKLQDFEVK 1029
G C V ++ ET ++VV+ +P F++KLQD +K
Sbjct: 16870 AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK 16929
Query: 1030 EK-DVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEK-RGHIRKLYIRNTSVHDEGE 1086
+ A + + A VVW +G+ ++ K+ Y + L I N + G
Sbjct: 16930 TAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 16989
Query: 1087 YSCILR----DESCTAEVTV--------VELPPEIITRLQNQKVNKGNKATFEIELT-KG 1133
Y+ + D +A++T+ P I L+ K+N AT I+ G
Sbjct: 16990 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELK-PKINVVEGATLSIQADLNG 17048
Query: 1134 DAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
+ V W KD SE+ S+ IQ+ DG +L + D L+D G Y+ N K
Sbjct: 17049 SPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEK 17101
Score = 123 bits (297), Expect = 1e-27
Identities = 121/517 (23%), Positives = 219/517 (42%), Gaps = 39/517 (7%)
Query: 510 PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F+ K +P+ + +++ + + G P PQ+ W ++ I++ + +Y D D L
Sbjct: 17993 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGD-FYYL 18051
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
+ V D G + C A N G + T+E+ V D +++ ++
Sbjct: 18052 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 18111
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESD 687
L G ++Q + + +EC + A P I W ++P + +++ + +
Sbjct: 18112 LPG---------RSQ-ANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGE 18161
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL----KS 743
C+ LK +V EGTY AVN G A + L++ + + I PL K
Sbjct: 18162 ----CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKI 18217
Query: 744 MIVRQ---GESVILSAQVVGNPRP-TITWCKNNKPVKALPTKSDGDTHSITILKPKKV-- 797
VR+ G V L+A++V P I W +N + P+ S + ++ L V
Sbjct: 18218 KSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFP 18277
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARV 856
+D G YT++A+N GIA + + V A+ + F+ T + G +++L A+V
Sbjct: 18278 EDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKV 18337
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
+P P I+W + + ++ E +G+ L I NV + D+G Y+ A N +G+++
Sbjct: 18338 IGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANV-TRADAGKYELTAINPSGQAN 18396
Query: 917 HGARVTIDVEKVTFVKHLQK------SYETEEGKTVILECQTSHT--VSTKWYHNKKE-I 967
+T+ V+ V K S +T E L S T + +W++N E I
Sbjct: 18397 AELELTV-VQSTKTVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI 18455
Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
G+D I G C +++Q
Sbjct: 18456 DGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTIRNQ 18492
Score = 118 bits (283), Expect = 6e-26
Identities = 156/683 (22%), Positives = 273/683 (39%), Gaps = 55/683 (8%)
Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSID 1339
V + + P+++ + +I + ++ L P P W + K II ++T+ +
Sbjct: 14444 VVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNE 14503
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEIDSS-S 1396
++L I ++ D G+YK+ +EN G A+ E V I D + + EI+
Sbjct: 14504 GSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELTEIEEGHD 14563
Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
I + E + ++ + + +++ ++ + + + +T T++ V
Sbjct: 14564 IELTC---EVSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADS-----GV 14615
Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
+ + +D TE ++ E Q P + P I + E + L C P KV W
Sbjct: 14616 YKCETTDGRSRTEGEVIVNE---QEPHILVGPQDAIVKDFGETMVLFCETSK-PVRKVKW 14671
Query: 1516 YRDGKKL--KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+++G ++ + KA EN R Y V +
Sbjct: 14672 FKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEKETSAPAKLVFEVAPN 14731
Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV- 1629
+I D H G+E+ G P P + NG L K + T+ SV
Sbjct: 14732 LIIPTEIRDGVTVH-AGNEFDFAVEFSGFPIPTIHLTNNGTPL---KAIAVVTEYDDSVS 14787
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689
+R+K++ +S + A + G E+ LK+ DKPS P + +E++ +SV + W+P
Sbjct: 14788 VRMKDVTLDNSGTVRVIAESPLGQCIKEIPLKIIDKPSAP-CDLQFKEVTEDSVFLSWQP 14846
Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
PL+ G LT Y IE+ DNNRW V T+ + L N Y FR++A N VG
Sbjct: 14847 PLETNGAPLTGYVIERKAVDNNRWRPCGQVKPTKLTFVAEDLFCNQVYGFRILAVNEVGE 14906
Query: 1750 SEALE---------SEPIVIKTALDVPSXXXXXX--XXXXIDNESVYITWFPSEKNGGSP 1798
SE + SEP+ + L VP +D V + W E+ +
Sbjct: 14907 SEPCDTVDVLTLESSEPVSESSELFVPKIAILRTPQVTVAVDETKVTLRW---EECPETS 14963
Query: 1799 IIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP--YTSDD 1855
+ YKVE K+ G W + + L+ + Y +++ A S P T+
Sbjct: 14964 L--YKVERKKVGDSDWLEIANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPV 15021
Query: 1856 KITIGKTLTPPSQPR---NFVVSESTSRSV--TLKWTEPESNGGSPITNYIIEFKTVKGK 1910
KI + + P S+ + SES +S + + + + S T +E K K
Sbjct: 15022 KILVPGSEMPASKTEKKTDAAKSESEQKSAEEIVAEKQVDQSQASESTTEAVEEKKTKKV 15081
Query: 1911 SWTKIVTVGGSVHEHCIENIKEK 1933
K+ G E ++ +KEK
Sbjct: 15082 VKKKVAENKG---EETLQEVKEK 15101
Score = 116 bits (280), Expect = 1e-25
Identities = 109/451 (24%), Positives = 187/451 (41%), Gaps = 29/451 (6%)
Query: 1512 KVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
KV W +DGK L+ K T YK + V+ S + I
Sbjct: 13996 KVVWLKDGKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDG----VDCSTHLSI 14051
Query: 1568 QQKPVI-TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
Q KPV+ +S D++ + + P +G LE D I +
Sbjct: 14052 QGKPVLKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDD 14111
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
+ + + ++ + +Y ++ N G + + +KV D PS P G V + + + + IE
Sbjct: 14112 GLKLTKRGVSKTDAGEYEVKLKNEFGEVAQKFDVKVNDTPSAP-GDVSVVKAESDCLHIE 14170
Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
W P +D G E+T Y IEK E ++ KVA V+ +Y + L Y+ R+ A N
Sbjct: 14171 WTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNK 14230
Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV-- 1804
G E +E++P+ + VP+ + + S ++W ++GGSP+ Y V
Sbjct: 14231 FGTGEFIETKPVQTGSPFQVPT-VEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDVYK 14289
Query: 1805 -EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKT 1862
E + E +K ++ LS Y+F+I A NE G S K+T+ +
Sbjct: 14290 RENEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVSKKLTV-EG 14348
Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
L P +V + V + W +S+G +++++K+ W V +GG
Sbjct: 14349 LVPEIILDMPMVKVLDNDKVEVTW---KSDGEK---EFVVQYKSDGSSIWAS-VDIGGPR 14401
Query: 1923 HEHC------IENIKEKDEIIFRISAENTVG 1947
E I+ ++E +FR++A N G
Sbjct: 14402 SESAATSKCIIDGLREGIPYVFRVAARNQHG 14432
Score = 113 bits (273), Expect = 1e-24
Identities = 88/381 (23%), Positives = 168/381 (44%), Gaps = 10/381 (2%)
Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG-EYSC 1178
+G+ E EL D V W +G + ++ + L I + + D+G E +
Sbjct: 13887 RGDNVEIEAELLAEDDTVTWKVNGKDADLNSRCHEMSHTFFRTLIIDEVEPTDSGMEITA 13946
Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI--PDETLDVTWYKKKSVI 1236
G T IL VEE ++F LP + ++V + P + V W K +
Sbjct: 13947 TCGTESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPL 14006
Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
E + +++ + +L +R+ +D +Y V +T L ++ + + +
Sbjct: 14007 EINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKPVLKNVSETKPV 14066
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
+ + +LLV Y + P+ + V+ K ++ ++ + LT + V TDAG
Sbjct: 14067 ITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLTKRGVSKTDAG 14126
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
Y+++L+N G + +V + D PS PG ++++ +S ++I W P + + YV
Sbjct: 14127 EYEVKLKNEFGEVAQKFDVKVNDTPSAPGDVSVVKAESDCLHIEWTAPTEDNGAEVTSYV 14186
Query: 1417 VEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
+E +E ++ V + +TS + +L+ + Y R AVN+ + ET V
Sbjct: 14187 IEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGTGEFIETK---PVQ 14243
Query: 1475 KETKIQSPTVEKP--LKNITT 1493
+ Q PTVE P + N+T+
Sbjct: 14244 TGSPFQVPTVEFPPTIDNVTS 14264
Score = 110 bits (264), Expect = 1e-23
Identities = 101/400 (25%), Positives = 169/400 (42%), Gaps = 28/400 (7%)
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDT--HSITILKPKK--------VKD---EG-- 801
+V+ N + +TW + + + KSDG + S+ I P+ + D EG
Sbjct: 14361 KVLDNDKVEVTWKSDGEKEFVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIP 14420
Query: 802 -VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
V+ + A N G E S ++A P + + + + +KG ++L +P
Sbjct: 14421 YVFRVAARNQHGTGEFSEPTIPVVVLADDA--PRVLKAIKPVKIPKKGELRLECHAAGHP 14478
Query: 861 VPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P WY++ + I P++ T+ +G L+I + E D G YK + N G + A
Sbjct: 14479 APEYIWYKDGKEIIPTDENTEIVNEGSMSALIIHELAGE-DVGLYKVLVENIHGTAESEA 14537
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE 978
V I + F + E EEG + L C+ S WY + K++ D +
Sbjct: 14538 EVGISDVRAHFNSSFSELTEIEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRVQFYAM 14597
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD--QETSTMLVVKETIPEFIRKLQDFEVKE-KDVAI 1035
R D GV KC D T ++V E P + QD VK+ + +
Sbjct: 14598 ARKRTLRIKGSTDADSGVYKCETTDGRSRTEGEVIVNEQEPHILVGPQDAIVKDFGETMV 14657
Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
L E + V W ++G I P+ NK E G L I+N HD G Y+ + ++
Sbjct: 14658 LFCETSKPVRKVKWFKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEKE 14717
Query: 1096 CTAEVTVV-ELPPEII--TRLQN-QKVNKGNKATFEIELT 1131
+A +V E+ P +I T +++ V+ GN+ F +E +
Sbjct: 14718 TSAPAKLVFEVAPNLIIPTEIRDGVTVHAGNEFDFAVEFS 14757
Score = 110 bits (264), Expect = 1e-23
Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 12/318 (3%)
Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDV 1248
T E FT P + N +T E ++ W+K K I ++ + +
Sbjct: 15593 TTESKKPAFT-NAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIA 15651
Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPP--KIVDYEREYRIKRGSD 1304
+L I + EDD+ EY V+ + + + K+ + + P ++ Y +G
Sbjct: 15652 GATSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQLPEINRVDRYASTLVFDKGET 15711
Query: 1305 VTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
V L + + PQP WI N+ K+I++ + K + LTI +++ D G + L+++
Sbjct: 15712 VKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFALKIK 15771
Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
N CG + + + D+P+ PGKP + + + S+ + W P N G S + Y VE
Sbjct: 15772 NRCGEDKYAIGIQVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEK 15831
Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
W + + ++ NL SYRFR A N S+ S+ +E V+K S
Sbjct: 15832 GKTWTKAEVTKQAFITLFNLVPGESYRFRVRADNTFGQSEPSDESELV-VVKNV---SRV 15887
Query: 1484 VEKP-LKNITTEPNEDIE 1500
VE+P K + + E ++
Sbjct: 15888 VEEPKKKEVKVKEQESVD 15905
Score = 108 bits (259), Expect = 5e-23
Identities = 114/496 (22%), Positives = 201/496 (40%), Gaps = 42/496 (8%)
Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ-FECQVEGYPRPQITWFRQTA-IIKPSQ 554
VFE+ + + AP ++L G + C V+G P P++ W++ + PS
Sbjct: 16240 VFERNIAFDTDAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSM 16299
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614
+ +Y++ +A L ++ + DAG +TC A N G + +L V+A T
Sbjct: 16300 KYDSFYNE-GLAELTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSP 16358
Query: 615 XXXXXXXXXXXADI-----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
+ + + +PP F + G +L +PEP + W
Sbjct: 16359 AVIEKKKDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYH 16418
Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
GE I +++ + + D Y L I +V EG + V N GE L +
Sbjct: 16419 NGEHISINDS-NYLRKHDKGRY--ELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVI 16475
Query: 730 GEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSD 783
+ + P + L + + + + L + NP P I W +N ++ L
Sbjct: 16476 PDGQYAPSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDG 16535
Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE------ENAEPPLFIN 837
+S+TI+ +D G Y A+N G A T + +EE + ++ P F
Sbjct: 16536 SGNYSLTII-DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRF-- 16592
Query: 838 RFQEITVKE--KGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
R Q T +E +G + LV V+ P P+I W ++++ I S ++ +G +I
Sbjct: 16593 RMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGA 16652
Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-------ETEEGKTVI 947
D D G Y C A N G + + +++++ H++ + T EG ++
Sbjct: 16653 RDD--DQGRYVCEAENIHGVAQSFS--VVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMV 16708
Query: 948 LE-CQTSHTVST-KWY 961
LE C T + T WY
Sbjct: 16709 LECCVTGKPIPTITWY 16724
Score = 108 bits (259), Expect = 5e-23
Identities = 124/516 (24%), Positives = 206/516 (39%), Gaps = 72/516 (13%)
Query: 638 KKPKAQYVDEGSDIL--LECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSV 694
KK V D++ L C + +P P + W +E+ VP S+ +S + +
Sbjct: 16256 KKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVP----SMKYDSFYNEGLAE 16311
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE------KEPPQVIEPLKS----- 743
L + N+ + G YT A N G L +K E K P VIE K
Sbjct: 16312 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSK 16371
Query: 744 -MIVRQ-------------------GESVILSAQVVGNPRPTITWCKNNKPVKALPT--- 780
+++ + GE IL P PT+ W N + + +
Sbjct: 16372 VVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYL 16431
Query: 781 -KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
K D + + IL DEG + +N+ G E+ A +TV P + A P F +
Sbjct: 16432 RKHDKGRYELHILSVDST-DEGKWKAVGKNAFGECESEAKLTVVIPDGQYA--PSFGKQL 16488
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ E +KL + NP P I W+RN I S+ FD + +T +D+
Sbjct: 16489 SDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYA 16548
Query: 900 -DSGDYKCVASNSAGKSSHGARVTIDV------EKVT------FVKHLQKSYETEEGKTV 946
DSG+YKCVA N GK+ V I+ +K+ F L E +G +
Sbjct: 16549 EDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADL 16608
Query: 947 ILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD- 1003
L C S T + KW + K I M ++++ E D G C ++
Sbjct: 16609 TLVCSVSGTPHPNIKWTKDDKPID-MSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENI 16667
Query: 1004 ---QETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
++ +++ +KE + P+F+ L + E + +LE + + + W +DG
Sbjct: 16668 HGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDG 16727
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
+ + + R + +L I N ++D+GEY+C
Sbjct: 16728 LKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTC 16763
Score = 97.9 bits (233), Expect = 7e-20
Identities = 124/553 (22%), Positives = 215/553 (38%), Gaps = 45/553 (8%)
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQSPTVEKPL--KN 1490
T + S L+ NS + + +++ +D +ET E + KET + V K + K
Sbjct: 15132 TSEKRSEAELEKNSEKSAEKKSTSADLEAADKAET-EKSETGKETTEKKKKVVKKVAKKG 15190
Query: 1491 ITTEPNEDIELTC-----IFGGVPQPKVT--WYRDGKKLKTAKATYENRXXXXXXX--XX 1541
+ IELT I V + V+ W +DGK L +
Sbjct: 15191 LVKADKSKIELTAGKEGEISAQVAETGVSVEWKKDGKALDASYTVTSTGGVSTVKIPIVD 15250
Query: 1542 XXXXXXYKCIAFNDHG-EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
+ C + G E E S V ++ V + E + KVGD ++A I P
Sbjct: 15251 VNTSGVFTCKVKSSEGDEEEVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISE-P 15309
Query: 1601 PPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
V W K+ ++ D + + T+ + I + +HS Y + N AG VE+
Sbjct: 15310 ASSVNWTKDDKPIKEDGNVKAQLSPDGTAQLTISKTDSAHSGIYKLNVENDAGKGKVEIA 15369
Query: 1660 LKVYDK----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
L++ P P GP++ +++ S WK P ++GG E+T Y +E+ E N W K
Sbjct: 15370 LRIKGAAKGAPGIPTGPIVFDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGW-K 15428
Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
++++ + L E +Y +V A N +G ALE + +K +
Sbjct: 15429 QCGKTKELK-FKADGLEEGTDYDVKVSAVNTMGTGSALEGKITTLKKKEETGKQKSEKSE 15487
Query: 1776 XXXIDNES------------VYI----TWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXX 1817
+ES Y+ T + + + Y V++K+ K W
Sbjct: 15488 SDEKKSESDKVSELKQIGKPEYVSSTATSIALKWTSDNDEVTYTVQMKEANSKRPWAVVA 15547
Query: 1818 XXXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP--RNFVV 1874
A I +L T+Y FR+ A+N+ G ++ + I K T +P N
Sbjct: 15548 KEISECSATIAQLKEGTSYLFRVIAQNKTGQTVTSEQSESIEC-KDTTESKKPAFTNAPT 15606
Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
+ ++ K T + +P ++ K + I + G+ I ++E D
Sbjct: 15607 DLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGAT-SLTIGEMREDD 15665
Query: 1935 EIIFRISAENTVG 1947
E ++I +NT G
Sbjct: 15666 EGEYKIVVKNTAG 15678
Score = 93.9 bits (223), Expect = 1e-18
Identities = 155/717 (21%), Positives = 281/717 (39%), Gaps = 84/717 (11%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN-KYDFEKRGHIRKL 1074
P R L D V E + +LEVE++ T + W DG+++ + + F+ R K+
Sbjct: 16815 PVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKI 16874
Query: 1075 YIRNTSVHDE--GEYSCILRDESCTAE---VTVVELP---------PEIITRLQNQKVNK 1120
Y H+E G+Y C + ++ E + VVE P P + +LQ+ +
Sbjct: 16875 Y----EAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 16930
Query: 1121 -GNKATFEIELTKGDAL-VRWFKDGSEIQF--SNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
G ATF + A V W +G +Q SN+ D L I + + G Y
Sbjct: 16931 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 16990
Query: 1177 SC----EVGNSKCTAILTVE-EPSINFTLRLPEFIL-----VPANTDAYLTVEIP---DE 1223
+ + G+ +A LT+ + LP FI+ + A L+++
Sbjct: 16991 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 17050
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+V W K S + ++++ + D L++R +D+ YT + K + EV
Sbjct: 17051 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 17110
Query: 1284 VEFPPKIVDYEREYR----------------IKRGSDVTLLVDY-QAFPQPNDEWIVNSK 1326
K V ++E + + R S + AF P++ + +
Sbjct: 17111 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADSYE 17170
Query: 1327 IIKKCKHTKPSID---SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
+ ++C + + +KS L IK + I+++ +N G + + L S
Sbjct: 17171 VERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLKTASV 17230
Query: 1384 PGKPNILEIDSSSINICWDEP-----ENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQ 1437
P S I D+ E +G T + + E +I E I V T +
Sbjct: 17231 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVA--TTST 17288
Query: 1438 TSIQNLKTNSSY-RFRAYAVNEVDISDAS-ETTEYYKV--IKETKIQS------PTVEKP 1487
+SI NLK+ F NE+ + AS + T + K ++ T S PT++K
Sbjct: 17289 SSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKA 17348
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXX 1542
L N + + + I LTC + V W++D +++++A + ++
Sbjct: 17349 LNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQS 17408
Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ--KPVITISNEDIKQKHKV-GDEWLVTAVIEGI 1599
Y+C+ N +G E+ C V ++ K + + + + G + +EG
Sbjct: 17409 QDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGS 17468
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS 1655
P PEV W K+G ++ + T E + + I + + Y A++ AG S
Sbjct: 17469 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDS 17525
Score = 93.1 bits (221), Expect = 2e-18
Identities = 58/185 (31%), Positives = 95/185 (51%), Gaps = 3/185 (1%)
Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
PS P + V ++ S + ++WT P + G+ +T+Y+IE K + + K+ TV G +
Sbjct: 14151 PSAPGDVSVVKAESDCLHIEWTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSY 14210
Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
+++++ + I RI+A N G E++ V+ VP+ P I V S
Sbjct: 14211 VVDDLEIETPYIVRIAAVNKFGTGEFIETKPVQTGSPFQVPTVEFPP-TIDNVTSTSCSL 14269
Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
SW P DGG+P+ GY++ R+ + W ++ G+ V T FN+R LS Y +I A
Sbjct: 14270 SWPKPIEDGGSPVYGYDVYKRE-NEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEAC 14328
Query: 2045 NEIGL 2049
NE GL
Sbjct: 14329 NEAGL 14333
Score = 92.7 bits (220), Expect = 3e-18
Identities = 139/664 (20%), Positives = 250/664 (37%), Gaps = 48/664 (7%)
Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG-EYSCILRDE 1094
+E E+ +E V W+ +G+ ++ R L I D G E + E
Sbjct: 13893 IEAELLAEDDTVTWKVNGKDADLNSRCHEMSHT-FFRTLIIDEVEPTDSGMEITATCGTE 13951
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNK-GNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151
S T + V ELP + + L + K G + T + L + V W KDG ++ +
Sbjct: 13952 SHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPLEINKD 14011
Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEFILVPA 1210
+ G L + +D+G+Y C+ L+++ +P + I V
Sbjct: 14012 YSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKPVLKNVSETKPVITVDK 14071
Query: 1211 NTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
+ L V P+ + +T K + + ++ D K T R ++ D EY
Sbjct: 14072 DDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLTK--RGVSKTDAGEYE 14129
Query: 1268 CVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
L + + K V+V + P D +K SD L +++ A + N + +
Sbjct: 14130 VKLKNEFGEVAQKFDVKVNDTPSAPGDVSV---VKAESDC-LHIEWTAPTEDNGAEVTSY 14185
Query: 1326 KIIKKCK-----HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI--- 1377
I KK H +++ K S + +E I ++ N G + +
Sbjct: 14186 VIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGTGEFIETKPVQTG 14245
Query: 1378 --LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNI 1433
P+ P I + S+S ++ W +P G S + Y V Y+ + EW ++ + +
Sbjct: 14246 SPFQVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDV-YKRENEGEWQKMNGEEL 14304
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
T++ +++ L + Y F+ A NE + S K+ E + ++ P+ +
Sbjct: 14305 VFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVS-KKLTVEGLVPEIILDMPMVKVL 14363
Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX------XXXXXXX 1546
N+ +E+T G + V + DG + + R
Sbjct: 14364 --DNDKVEVTWKSDGEKEFVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIPY 14421
Query: 1547 XYKCIAFNDHGEVETS-----CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
++ A N HG E S VV P + + + +K K E + G P
Sbjct: 14422 VFRVAARNQHGTGEFSEPTIPVVVLADDAPRVLKAIKPVKIPKK--GELRLECHAAGHPA 14479
Query: 1602 PEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PE IWYK+G + + D+ I + S + I EL Y + N GT+ E +
Sbjct: 14480 PEYIWYKDGKEIIPTDENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEV 14539
Query: 1661 KVYD 1664
+ D
Sbjct: 14540 GISD 14543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 99/445 (22%), Positives = 176/445 (39%), Gaps = 37/445 (8%)
Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQ 557
P + + AP VE L DG + C++ P + W + ++ ++D
Sbjct: 812 PPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVT 871
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXX 615
D V L+ E F EDAG + C A N G A + + VE + DH E +
Sbjct: 872 TTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDH-EEAEISE 930
Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQ--YVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
D+ +PP F + A+ + + + + ++ ++W G +
Sbjct: 931 SVLTD------DVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMD 984
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
I +E V +D ++ TN+ G YT A + G ++ +++ +
Sbjct: 985 IYENEKYEVMQFADGAQILTIRAPTNL---DSGVYTCTAESEHGVSNSSCQVELTISAES 1041
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
P+ E ++ + E V + G K A K + + +
Sbjct: 1042 SPESFEKVE---ITPPEEV----KETGIDDDIEVILKEEVSGTAQIEKREEEFKLLV--- 1091
Query: 794 PKKVKDEGVYTLKAE-NSEGIAE-TSAVITVEEPTEEN----AEPPLFINRFQEITVKEK 847
KV D+ TL A E + E ++ E+ E+N + P F E VKE
Sbjct: 1092 --KVADQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQEPRFETSTDEYHVKEN 1149
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
GTIK+ A ++ +P P + WY E + S+ ++ ++ +++ NV G+Y
Sbjct: 1150 GTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKR-QGGNYFLR 1208
Query: 908 ASNSAGKSSHGARVTID-VEKVTFV 931
A N G+S ++T+D +E VT V
Sbjct: 1209 AHNCHGESILPMKLTVDPIEAVTHV 1233
Score = 83.4 bits (197), Expect = 2e-15
Identities = 142/699 (20%), Positives = 267/699 (38%), Gaps = 68/699 (9%)
Query: 1007 STMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEINS--ETADVVWERDGEIIKPKKNKY 1063
+T+L V+E +F++ L + KE + V +N + + VVW +DG+ ++ K+ Y
Sbjct: 13954 TTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPLEINKD-Y 14012
Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK----VN 1119
+ G L +R D G+Y + C+ +++ P ++ + K V+
Sbjct: 14013 SIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKP--VLKNVSETKPVITVD 14070
Query: 1120 KGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
K ++ + + +A DG +++F ++ + KL DAGEY
Sbjct: 14071 KDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLTKRGVSKTDAGEYEV 14130
Query: 1179 EVGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAY---LTVEIPDETLDVTWY---K 1231
++ N + + + +N T P + +V A +D T D +VT Y K
Sbjct: 14131 KLKN-EFGEVAQKFDVKVNDTPSAPGDVSVVKAESDCLHIEWTAPTEDNGAEVTSYVIEK 14189
Query: 1232 KKS---------VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST---TKL 1279
K+S + + ++ D++ T I + ++ T ++ K +
Sbjct: 14190 KESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFG-TGEFIETKPVQTGSPF 14248
Query: 1280 KVEVVEFPPKIVDY-EREYRIKRGSDV----TLLVDYQAFPQPND-EWI-VNSKIIKKCK 1332
+V VEFPP I + + + + + Y + + N+ EW +N + + +
Sbjct: 14249 QVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDVYKRENEGEWQKMNGEELVFTE 14308
Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
S K +AG L +N ++ V L P + +
Sbjct: 14309 SFNVRALSSGKEYEFKIEACNEAG-----LRSNSNVVSKKLTVEGLVPEIILDMPMVKVL 14363
Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-------KNITKTQTSIQNLKT 1445
D+ + + W ++ G +VV+Y+ ++ W SV ++ ++ I L+
Sbjct: 14364 DNDKVEVTW---KSDGEKE---FVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLRE 14417
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
Y FR A N+ + SE T V+ + +P V K +K + ++ L C
Sbjct: 14418 GIPYVFRVAARNQHGTGEFSEPTIPVVVLAD---DAPRVLKAIKPVKIPKKGELRLECHA 14474
Query: 1506 GGVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
G P P+ WY+DGK++ T + YK + N HG E
Sbjct: 14475 AGHPAPEYIWYKDGKEIIPTDENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAE 14534
Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI-WYKNGNKLENDKEY 1619
+ VGI V N + ++ + + E V+ WYK+G KL
Sbjct: 14535 SEAEVGISD--VRAHFNSSFSELTEIEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRV 14592
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
+ +RIK + S Y E ++ + EV
Sbjct: 14593 QFYAMARKRTLRIKGSTDADSGVYKCETTDGRSRTEGEV 14631
Score = 82.6 bits (195), Expect = 3e-15
Identities = 108/496 (21%), Positives = 203/496 (40%), Gaps = 54/496 (10%)
Query: 502 TSEEQSMAPIFVEKL--RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
+S S P FV L R HT + + +C+ G P P W + ++ Q +Q+
Sbjct: 3889 SSITSSTRPHFVVPLPERVTHTVNDH-ITIKCKFSGQPLPAAMW-EKDGVLLDLQKYQVT 3946
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH-GSEMT-VXXXX 617
+D + L I +D +TC N AG S++ + V + DH G + T +
Sbjct: 3947 -TEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDV---VDDHLGLQQTGLHVMC 4002
Query: 618 XXXXXXXXADILE----------GIPP---TFSKKPKAQYVDEGSDIL------LECRLV 658
DIL PP T +++P + ++ L+C ++
Sbjct: 4003 ERDQNDVELDILVQSPNHLGVTFNFPPVNRTLARQPPYFLLPLSDKVVIDEKCTLKCVVM 4062
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
IP + W+ G + D+N + E + ++L++ N+KK + A+N +G+
Sbjct: 4063 GIPLVIVKWIVDGVVVTEDDNHEIHFEDGI----ALLRMKNIKK-DKSVVQCEAINCKGK 4117
Query: 719 ASLPIVL------KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
+ VL + + G+ + P + LK + L VVG P P ++ N
Sbjct: 4118 VTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTT-DHATLKCIVVGTPLPDVSCSFNG 4176
Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEG-VYTLKAENSEGIAETSAVITVEEPTEENAE 831
+ DG I +++ V +EG V N G + ++ V+ + + E+N +
Sbjct: 4177 VTDNSKIRSEDG----IVLIQVNDVTEEGIVVECTISNETGSSTSNCVVKIIKQEEKNYQ 4232
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIEL 890
P+ + Q +V + + + V +P P++ W N + I F DG I L
Sbjct: 4233 RPIIVFN-QAGSVNNERELSVKVGVIASPEPTLFWKHNGKSIEEGGDYYLIFEDGIGI-L 4290
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE---KVTFVKHLQKSYETEEGKTVI 947
+ N+ S ++ C+A N G+++ V I ++ K+T VK L ++ +
Sbjct: 4291 KVFNIQD--GSHEFTCIAKNEYGQTTVEIPVEIGLKTENKLTLVKTLNDIAVVDDIVQLK 4348
Query: 948 LECQTSHTVSTKWYHN 963
+ + + KW+ +
Sbjct: 4349 IVAEGDLPIEFKWFED 4364
Score = 82.6 bits (195), Expect = 3e-15
Identities = 108/519 (20%), Positives = 204/519 (39%), Gaps = 34/519 (6%)
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG-IPPPEVIWYKNGNKLEN 1615
G + ++ +++ PV + K K G E ++ + I +V+W K+G LE
Sbjct: 13949 GTESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPLEI 14008
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
+K+Y+I T + + ++ K S KY + ++ + + K K PVI
Sbjct: 14009 NKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKPVLKNVSETKPVIT 14068
Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
+ + + + +T + E D I V D + + K +
Sbjct: 14069 VDKDDQFSLLVAYDSNPEASFSMTVDG-KDLEFDGRSRIDVVDDGLKLTKRGVSKTDAG- 14126
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
EY ++ + F E + + + D PS +++ ++I W ++
Sbjct: 14127 EYEVKLKNE----FGEVAQKFDVKVN---DTPSAPGDVSVVKA-ESDCLHIEWTAPTEDN 14178
Query: 1796 GSPIIDYKVEIKQEGKK--WKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYT 1852
G+ + Y +E K+ G++ K + + L I T Y RI A N+ GT +
Sbjct: 14179 GAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGTG-EFI 14237
Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
+ G P+ + TS S +L W +P +GGSP+ Y + +K W
Sbjct: 14238 ETKPVQTGSPFQVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDV-YKRENEGEW 14296
Query: 1913 TKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
K+ + S + + + KE + F+I A N G+ + S +L VP
Sbjct: 14297 QKMNGEELVFTESFNVRALSSGKEYE---FKIEACNEAGLRSNSNVVSKKLTVEGLVPEI 14353
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW--MEVG---KVDVNT 2023
++++ ++ V +W + DG + + + ++W +++G T
Sbjct: 14354 ILDMPMVKVLDNDKVEVTWKS---DGEKEFV---VQYKSDGSSIWASVDIGGPRSESAAT 14407
Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
K I L E Y+ R+ ARN+ G E E P V+
Sbjct: 14408 SKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVVVL 14446
Score = 82.6 bits (195), Expect = 3e-15
Identities = 75/286 (26%), Positives = 121/286 (42%), Gaps = 16/286 (5%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR-WF 1140
H GE+S E V + + P ++ ++ K+ K + E A W+
Sbjct: 14431 HGTGEFS-----EPTIPVVVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWY 14485
Query: 1141 KDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPS 1195
KDG EI + ++ +G L I++ +D G Y V G ++ A + + +
Sbjct: 14486 KDGKEIIPTDENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVR 14545
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK--KKSVIEDTEKFTLISDVKKRTL 1253
+F E + D LT E+ DE V WYK KK V D +F ++ +KRTL
Sbjct: 14546 AHFNSSFSELTEIEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRVQFYAMA--RKRTL 14603
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
I+ T+ D Y C D +S T+ +V V E P I+ ++ +K + +L +
Sbjct: 14604 RIKGSTDADSGVYKCETTDGRSRTEGEVIVNEQEPHILVGPQDAIVKDFGETMVLFCETS 14663
Query: 1314 FPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
P +W N +I + D K A+L IK + D G Y
Sbjct: 14664 KPVRKVKWFKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAY 14709
Score = 78.6 bits (185), Expect = 5e-14
Identities = 63/261 (24%), Positives = 114/261 (43%), Gaps = 7/261 (2%)
Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
N++ + + D W+ V+ E+ + + L + K ++ Y VL
Sbjct: 8780 NSEVIIKCKTSQPISDAKWFCNGMVLLPDEQVNMTVTGCEAVLRLVKFLPQNKGNYH-VL 8838
Query: 1271 LDAKSTTKLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
+D ++ + PP I++ + + G T ++ P P + N + +
Sbjct: 8839 IDGSIGSQPAILSGPVPPVILNKLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVS 8898
Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
K I ASL I K+ D G Y + LEN G + ++++T++D P P K +
Sbjct: 8899 F--DVKYEIYDNIASLYIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKPRKAQL 8956
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSS 1448
+ + +S W P +TG S I++Y+V + ++ W ++ ++ KT T+I+ L N
Sbjct: 8957 VALTDTSATFKW-LPPHTGESDILHYIVMRRSTESRRWRNIGHVQEKTFTAIE-LVPNEF 9014
Query: 1449 YRFRAYAVNEVDISDASETTE 1469
Y FR AVN SE E
Sbjct: 9015 YAFRIVAVNGFGEGAPSEIIE 9035
Score = 77.4 bits (182), Expect = 1e-13
Identities = 68/238 (28%), Positives = 113/238 (47%), Gaps = 23/238 (9%)
Query: 700 VKKFQEGT---YTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
+ + +EGT + V+A N+ G E S I K T K+P P V+ G++
Sbjct: 15557 IAQLKEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTESKKPAFTNAPTDLTAVKNGKT 15616
Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
I +A+ G+P P I W KN K + K ++ S+TI + ++ DEG Y + +
Sbjct: 15617 KI-TAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMRE-DDEGEYKIVVK 15674
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867
N+ G E S +T+++ E N ++R+ V +KG T+KL + P P + W
Sbjct: 15675 NTAGSVEHSCKLTMDQLPEINR-----VDRYASTLVFDKGETVKLRLSFSGRPQPEVIWI 15729
Query: 868 RNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH--GARVT 922
NN ++I S + N L I ++DS+ D G++ N G+ + G +VT
Sbjct: 15730 DNNGKVIEESRKMKIEKTVLNTVLTINSIDSQ-DQGEFALKIKNRCGEDKYAIGIQVT 15786
Score = 75.8 bits (178), Expect = 3e-13
Identities = 127/625 (20%), Positives = 226/625 (36%), Gaps = 65/625 (10%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
DGS ++ P W ++ +Q+ + D++N + + ++ P G T
Sbjct: 608 DGSPLKLRVMASSLPPATFLWMLNNFELRSNQNVTIRNDEENSSEIEFQKA-PN--GNVT 664
Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
AKN G T ++I++ G ++T A I + +P
Sbjct: 665 VSAKNHLGEDRWTGKVILQYESPPPGQKITTIEKVTESWTLEEAVITQVVPTA------- 717
Query: 643 QYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
D G I++ R + W G I E VA+ES + S L + +
Sbjct: 718 --ADPGDRIVIIVRFDENKTSNCQFNWTINGVNIEKLEENLVAVESTE--FESSLIVEKL 773
Query: 701 KKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKE------------PPQVIEPLKSMIVR 747
++ G V N+ GE S L+I+ + P+++EPL S
Sbjct: 774 EEQLCGEVVCVVKNQHGEVFSSSAHLRIRDDDSSFEIVPPNLPEECAPKIVEPLHSASFL 833
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI-----TILKPK-KVKDEG 801
G+++ L ++ NP + W K++ V+ D T + +L P+ +D G
Sbjct: 834 DGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCELLNPECFAEDAG 893
Query: 802 VYTLKAENSEGIAETSAVITVEE----PTEENAE--------------PPLFINRFQEIT 843
+Y A N G AET+A I VE E AE PP FI T
Sbjct: 894 LYKCTATNPHGTAETAAFINVEGAEYIKDHEEAEISESVLTDDVHIILPPKFIETLTAET 953
Query: 844 --VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
++ G +++VA V +++W ++ I +E + +++ + +DS
Sbjct: 954 DNFQQLGYVRMVATVRSVAPITVSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDS 1013
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET------EEGKTVILECQTSHT 955
G Y C A + G S+ +V + + + + +K T E G +E
Sbjct: 1014 GVYTCTAESEHGVSNSSCQVELTISAESSPESFEKVEITPPEEVKETGIDDDIEVILKEE 1073
Query: 956 VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET 1015
VS K+E ++ + V K + + E +
Sbjct: 1074 VSGTAQIEKREEEFKLLVKVADQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQ 1133
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
P F ++ VKE + I+ T + W E ++ +N + + G +
Sbjct: 1134 EPRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAG-TSAI 1192
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE 1099
++N G Y LR +C E
Sbjct: 1193 ILKNVQKRQGGNY--FLRAHNCHGE 1215
Score = 74.9 bits (176), Expect = 6e-13
Identities = 71/262 (27%), Positives = 110/262 (41%), Gaps = 22/262 (8%)
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
R++ ++++ + R+ A + +G + +I + K + PS P + E T SV L
Sbjct: 14789 RMKDVTLDNSGTVRVIAESPLGQCIK-----EIPL-KIIDKPSAPCDLQFKEVTEDSVFL 14842
Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
W P G+P+T Y+IE K V W V + E++ FRI A N
Sbjct: 14843 SWQPPLETNGAPLTGYVIERKAVDNNRWRPCGQVKPTKLTFVAEDLFCNQVYGFRILAVN 14902
Query: 1945 TVGVSLPTESQSV-RLEKHATVPS------PPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
VG S P ++ V LE V P A L V + T T W+
Sbjct: 14903 EVGESEPCDTVDVLTLESSEPVSESSELFVPKIAILRTPQVTVAVDETKV-TLRWEECPE 14961
Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y + + V + W+E+ D N KF R L+E+ Y+ ++ A +S P E
Sbjct: 14962 TSLYKVERKKVGDSDWLEIANTDRN--KFKDRSLTESGEYVYQVTATGIHAVSSPSEETN 15019
Query: 2058 PFKV-IPGEGSHADEEPGEQTE 2078
P K+ +PG E P +TE
Sbjct: 15020 PVKILVPG-----SEMPASKTE 15036
Score = 74.1 bits (174), Expect = 1e-12
Identities = 64/270 (23%), Positives = 113/270 (41%), Gaps = 11/270 (4%)
Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
I + A + ++ ++ + + V W K ++ + +T+ S T+ I +
Sbjct: 15199 IELTAGKEGEISAQVAETGVSVEWKKDGKALDAS--YTVTSTGGVSTVKIPIVDVNTSGV 15256
Query: 1266 YTCVLLDAKSTTK-LKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWI 1322
+TC + ++ + + + V P++ E E I + DV L + P + W
Sbjct: 15257 FTCKVKSSEGDEEEVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISEPASSVNWT 15316
Query: 1323 VNSKIIKKCKHTKPSIDSK-SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK- 1380
+ K IK+ + K + +A LTI K ++ +GIYKL +EN+ G VE+ + I
Sbjct: 15317 KDDKPIKEDGNVKAQLSPDGTAQLTISKTDSAHSGIYKLNVENDAGKGKVEIALRIKGAA 15376
Query: 1381 ---PSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
P P P + + + SS W PEN G I Y VE +E W +
Sbjct: 15377 KGAPGIPTGPIVFDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQCGKTKEL 15436
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
+ L+ + Y + AVN + A E
Sbjct: 15437 KFKADGLEEGTDYDVKVSAVNTMGTGSALE 15466
Score = 73.7 bits (173), Expect = 1e-12
Identities = 79/303 (26%), Positives = 125/303 (41%), Gaps = 24/303 (7%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIES 686
+L P K K + + ++ LEC P P+ W G+EI+P DEN + E
Sbjct: 14445 VLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNEG 14504
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
M S L I + G Y V+ N G A + I L +
Sbjct: 14505 SM----SALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELTE--I 14558
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITI-LKPKKVKDEGVYT 804
+G + L+ + V + + W K+ K + A + T+ +K D GVY
Sbjct: 14559 EEGHDIELTCE-VSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADSGVY- 14616
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
K E ++G + T + V E EP + + Q+ VK+ G ++ T PV +
Sbjct: 14617 -KCETTDGRSRTEGEVIVNE-----QEPHILVGP-QDAIVKDFGETMVLFCETSKPVRKV 14669
Query: 865 TWYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
W++N I P ++ I +N DG+ L I N D D G Y AS S ++S A++
Sbjct: 14670 KWFKNGVEIWPQMNKAIMEN-DGKRATLEIKNFDKH-DIGAY--TASVSEKETSAPAKLV 14725
Query: 923 IDV 925
+V
Sbjct: 14726 FEV 14728
Score = 73.3 bits (172), Expect = 2e-12
Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Query: 1800 IDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
ID ++ +E +K K I + +F + +N G +DK I
Sbjct: 15729 IDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFALKIKNRCG-------EDKYAI 15781
Query: 1860 GKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VT 1917
G +T P+ P V + SV L+W P ++GGSP+ NY +E T KGK+WTK VT
Sbjct: 15782 GIQVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWTKAEVT 15841
Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ + N+ + FR+ A+NT G S P++ + + K+ +
Sbjct: 15842 KQAFI---TLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVS 15885
Score = 72.9 bits (171), Expect = 2e-12
Identities = 89/420 (21%), Positives = 167/420 (39%), Gaps = 33/420 (7%)
Query: 1274 KSTTKLKV--EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-K 1330
+ T+K+ V E+++ PP ++ K G L+V P+P +W N + I
Sbjct: 16367 RKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISIN 16426
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKP 1387
+ D L I V++TD G +K +N G + E +T++ + +P
Sbjct: 16427 DSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGK 16486
Query: 1388 NILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNL 1443
+ ++ S +I E N + I + EI+ ++ ++ +I +
Sbjct: 16487 QLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDA 16546
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVI--KETKI---QSPTVEKPLKNITTEPN-E 1497
S ++ A N++ + +++ + KI ++P L P
Sbjct: 16547 YAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGA 16606
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRX-XXXXXXXXXXXXXXYKCIAFN 1554
D+ L C G P P + W +D K + + + +EN Y C A N
Sbjct: 16607 DLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAEN 16666
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKV---------GDEWLVTAVIEGIPPPEVI 1605
HG ++ VV I++ + + ++ K G+E ++ + G P P +
Sbjct: 16667 IHGVAQSFSVVEIKE----AVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTIT 16722
Query: 1606 WYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYK+G KL ++ T ++ S + I + + +YT EA N+ G T+KV D
Sbjct: 16723 WYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 16782
Score = 72.1 bits (169), Expect = 4e-12
Identities = 102/420 (24%), Positives = 173/420 (41%), Gaps = 44/420 (10%)
Query: 1002 KDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK 1057
KD++TS ++V++E I P F LQD E K + IL V + V W +GE I
Sbjct: 16365 KDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHIS 16424
Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAE--VTVV----ELPPEI 1109
+ Y + +L+I + DEG++ + ++ C +E +TVV + P
Sbjct: 16425 INDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSF 16484
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID--GKKQKLKIY 1166
+L + K ++ + E+ + A + WF++ SEI+ S H +L D L I
Sbjct: 16485 GKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTII 16544
Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEE------------PSINFTLRLPEFILVPA 1210
D +D+GEY C ++G + + +EE + F ++LP VP
Sbjct: 16545 DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQ 16604
Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
D L + ++ W K I+ + K + + TL I +DDQ Y C
Sbjct: 16605 GADLTLVCSVSGTPHPNIKWTKDDKPIDMSNK-QVRHENGVCTLHIIGARDDDQGRYVCE 16663
Query: 1270 ------LLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
+ + S ++K V+ PK ++ G+++ L P P W
Sbjct: 16664 AENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITW 16723
Query: 1322 IVNS-KIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
+ K+I + + + + D K S L I V D G Y N+ G V ++D
Sbjct: 16724 YKDGLKLIIENRMLQYT-DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 16782
Score = 70.9 bits (166), Expect = 9e-12
Identities = 55/202 (27%), Positives = 85/202 (42%), Gaps = 19/202 (9%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536
+P + L + N + L +F GVPQP ++W D +L + EN
Sbjct: 3788 APVFTERLPSSACFANSKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAI 3847
Query: 1537 XXXXXXXXXXXY-KCIAFNDHGEVETSC-VVGIQQKPVITISNEDIKQK----------- 1583
+ KC A N G+VETSC +V + VI+ S+ +
Sbjct: 3848 RFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERV 3907
Query: 1584 -HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
H V D + G P P +W K+G L+ K Y +TT++ TS+++I+ +
Sbjct: 3908 THTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQK-YQVTTEDGTSILKIESASLDDKAV 3966
Query: 1643 YTIEASNTAGTSSVEVTLKVYD 1664
YT +N AG S T+ V D
Sbjct: 3967 YTCTIANEAGCESTSCTIDVVD 3988
Score = 70.5 bits (165), Expect = 1e-11
Identities = 75/349 (21%), Positives = 142/349 (40%), Gaps = 28/349 (8%)
Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
H+ G + G P P + NG + D +Y I + + + I ++ + +Y
Sbjct: 8868 HQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIY--DNIASLYIPKMSKRDGGEY 8925
Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
T+ N G ++ + + D P KP ++ ++ S T +W PP G ++ Y +
Sbjct: 8926 TVVLENKYGKDESDLHITMVDTPLKPRKAQLV-ALTDTSATFKWLPP-HTGESDILHYIV 8983
Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT- 1762
+ ++ RW + V +T+ +L N Y FR++A N GF E SE I + T
Sbjct: 8984 MRRSTESRRWRNIGHVQE--KTFTAIELVPNEFYAFRIVAVN--GFGEGAPSEIIEVNTL 9039
Query: 1763 ------ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
+ D ++NE +T E++ I+ ++K++ KK K
Sbjct: 9040 DYDQEESFDFAGEEELKLDDVQVNNE--VVTEITIEES--EVTIEEHRKLKKKSKKSKKT 9095
Query: 1817 XXXXXXXARIQ-KLSINTTYQFRIYARNEIGTSLPYTSD--------DKITIGKTLTPPS 1867
+ I ++S + T I + I + P + + + T+ K P
Sbjct: 9096 TDEPELDSEIALEVSSDITSSLEITTESTIPDTAPESQETLNVEIAVTETTVQKITNPSD 9155
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
+ V+E T+ S +K + + N S + + K ++GK KI+
Sbjct: 9156 ESAKKDVNEDTAVSSIVKKDDKDVNKKSLPESGLTTKKEIQGKPEKKIM 9204
Score = 70.1 bits (164), Expect = 2e-11
Identities = 80/320 (25%), Positives = 121/320 (37%), Gaps = 42/320 (13%)
Query: 1480 QSPTVEKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538
Q PT K L+++ + E TC P +V W +GK L+ K+ Y+ R
Sbjct: 16915 QMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNT 16974
Query: 1539 XXXXXXXXX------YKCIAFNDHGEVETSCVVGIQQKPVITISNE------DIKQKHKV 1586
Y +A N G+V TS + I I+ ++K K V
Sbjct: 16975 ATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINV 17034
Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + A + G P PEV+W K+ ++L + + ++++ YT
Sbjct: 17035 VEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYT 17094
Query: 1645 IEASNTAG----------TSSVEVTLKVYDK-----------PSKPEGPVIMREISRESV 1683
I A N G T S EV K K P +P P E V
Sbjct: 17095 ITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQV 17154
Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
T+ + P +G + Y +E+ PD W+ + +E I+ L N EY+FRV
Sbjct: 17155 TMAFDAP-SEGPAD--SYEVERRCPDQREWVSCGST-KSLELE-IKGLTPNTEYIFRVAG 17209
Query: 1744 QNPVGFSEALESEPIVIKTA 1763
+N G E E +KTA
Sbjct: 17210 KNKQGLGEWSEMTS-TLKTA 17228
Score = 70.1 bits (164), Expect = 2e-11
Identities = 106/437 (24%), Positives = 167/437 (38%), Gaps = 56/437 (12%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F+ K + +V E+ ++ L+ I+ V W+++G II NKY G L
Sbjct: 17993 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG-IILETGNKYSIYNDGDFYYL 18051
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL 1130
+ + S D+G Y+C + +CT+E+ V+ + ++ +K K KA IE+
Sbjct: 18052 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 18111
Query: 1131 TKG------------DALVRWFKDGSEIQFSNHIQL---------TIDGKKQKLKIYDCD 1169
G + V + S I N ++L + DG+ LK
Sbjct: 18112 LPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVT 18171
Query: 1170 LDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFIL---------VPANTDAYL 1216
D G Y+CE N +A+ L V N +P V + L
Sbjct: 18172 PGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVEL 18231
Query: 1217 TVEI--PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272
E+ E L + W + K I D+ F+ L I +D EYT +
Sbjct: 18232 AAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQS 18291
Query: 1273 --AKSTTKLKVE-----VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VN 1324
A+ T +L V V + P++ D+E R G V L P P W
Sbjct: 18292 GIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAG 18351
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K+ + K+ + K L I V DAG Y+L N G A+ E+ +T++
Sbjct: 18352 QKLNNEEKYMMRNEGDKFI-LRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTV 18410
Query: 1385 G-KPNILEIDSSSINIC 1400
G KP E S+ C
Sbjct: 18411 GAKPKFNE-SPISVQTC 18426
Score = 68.1 bits (159), Expect = 6e-11
Identities = 63/273 (23%), Positives = 109/273 (39%), Gaps = 8/273 (2%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXX 1538
SP + +P+ TE + + T F P V W RD ++++ A KA+ E
Sbjct: 10273 SPFISQPVSATVTEMAGEAKFTVKFSRKPI-YVKWMRDDREIRVAYGKASVETTDDSSVL 10331
Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
I E ++ + ++ IT+ + + G ++ I
Sbjct: 10332 VIKNIDGKDVGNIYAVFDSEYRSAMARLDLRVPCKITLESSSNAPEIVAGKNLDLSFKIS 10391
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P I + N+ + ++T + + IR+K LK S + I N + +
Sbjct: 10392 GYPLPTNIELLHNNENLRTRS-DVTDFDDSISIRMKRLKLEDSGEIKIIGKNDSSEDQLR 10450
Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+ + V + SKP + + RE+VT+ W P + G + +Y +E+ D RW
Sbjct: 10451 IPINVIEVTSKPTS-LQVTSTERETVTLTWSLPTELNGSNVNEYLVERKTVDGGRWRHAC 10509
Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
V + L EY+FRV+A N G S
Sbjct: 10510 TVTD--SRAVVDGLFSGTEYVFRVVAVNGAGQS 10540
Score = 66.1 bits (154), Expect = 3e-10
Identities = 57/283 (20%), Positives = 116/283 (40%), Gaps = 15/283 (5%)
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
D + V + K D +I ++ + + D + LD + K+ +
Sbjct: 10310 DREIRVAYGKASVETTDDSSVLVIKNIDGKDVGNIYAVFDSEYRSAMARLDLRVPCKITL 10369
Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
E P+IV G ++ L +P P + ++++ + + D
Sbjct: 10370 ESSSNAPEIV---------AGKNLDLSFKISGYPLPTNIELLHNNENLRTRSDVTDFDD- 10419
Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
S S+ +K+++ D+G K+ +N+ + + + +++ S P + + ++ + W
Sbjct: 10420 SISIRMKRLKLEDSGEIKIIGKNDSSEDQLRIPINVIEVTSKPTSLQVTSTERETVTLTW 10479
Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
P S + Y+VE + +D W +T ++ + L + + Y FR AVN
Sbjct: 10480 SLPTELNGSNVNEYLVERKTVDGGRWRHACTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQ 10539
Query: 1462 SDASE----TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
S S+ TT+ + I ET SP VEK + ++ +P E
Sbjct: 10540 SAPSDTIEATTQAEEEIDETVPTSP-VEKVKEPVSKKPENTKE 10581
Score = 65.3 bits (152), Expect = 5e-10
Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 9/157 (5%)
Query: 802 VYTLKAENSEG---IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
++ + A+N G +E S I ++ TE ++ P F N ++T + G K+ A T
Sbjct: 15567 LFRVIAQNKTGQTVTSEQSESIECKDTTE--SKKPAFTNAPTDLTAVKNGKTKITAEFTG 15624
Query: 859 NPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
+P P I W++N EI S +N G L I + E D G+YK V N+AG H
Sbjct: 15625 HPAPEIHWFKNKKEIFSGKRQWIENIAGAT-SLTIGEM-REDDEGEYKIVVKNTAGSVEH 15682
Query: 918 GARVTID-VEKVTFVKHLQKSYETEEGKTVILECQTS 953
++T+D + ++ V + ++G+TV L S
Sbjct: 15683 SCKLTMDQLPEINRVDRYASTLVFDKGETVKLRLSFS 15719
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/247 (25%), Positives = 96/247 (38%), Gaps = 20/247 (8%)
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
KT+ + +A N I++ + K + +P PL ++ L+C
Sbjct: 17623 KTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSC 17682
Query: 1504 IFGGVPQPKVTW-YRD--GKKLKTAKAT-------YENRXXXXXXXXXXXXXXXYKCIAF 1553
G P+P + W Y D G K+ +T + Y+CIA
Sbjct: 17683 NVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIAT 17742
Query: 1554 NDHGEVETSC--VVG-IQQKPV----ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
N G+ T C +VG + +P +D K E+ V + G P P++ W
Sbjct: 17743 NSSGQATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVE--LAGFPTPDLTW 17800
Query: 1607 YKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
Y N K+ K+ IT + TSV+ IK + + Y +EASN G L V D+
Sbjct: 17801 YHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDE 17860
Query: 1666 PSKPEGP 1672
K E P
Sbjct: 17861 RRKAEPP 17867
Score = 62.5 bits (145), Expect = 3e-09
Identities = 39/152 (25%), Positives = 75/152 (49%), Gaps = 11/152 (7%)
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRNFVVSESTSRSVT 1883
R+++L + + + +I +N+ +S+D++ I + S+P + V+ + +VT
Sbjct: 10424 RMKRLKLEDSGEIKIIGKND-------SSEDQLRIPINVIEVTSKPTSLQVTSTERETVT 10476
Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
L W+ P GS + Y++E KTV G W TV S ++ + E +FR+ A
Sbjct: 10477 LTWSLPTELNGSNVNEYLVERKTVDGGRWRHACTVTDS--RAVVDGLFSGTEYVFRVVAV 10534
Query: 1944 NTVGVSLPTESQSVRLEKHATV-PSPPTAPLE 1974
N G S P+++ + + + PT+P+E
Sbjct: 10535 NGAGQSAPSDTIEATTQAEEEIDETVPTSPVE 10566
Score = 61.7 bits (143), Expect = 6e-09
Identities = 121/594 (20%), Positives = 223/594 (37%), Gaps = 57/594 (9%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP+F E+L S + E G P+P I+W + + ++ V+ +
Sbjct: 3788 APVFTERLPSSACFANSKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAI 3847
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE---APLSDHGSEMTVXXXXXXXXXXXX 625
V G C A N AG ++ E++ + +SD +
Sbjct: 3848 RFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERV 3907
Query: 626 ADILEG---IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE---- 678
+ I FS +P + E +LL+ + + D + K E D+
Sbjct: 3908 THTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKYQVTTEDGTSILKIESASLDDKAVY 3967
Query: 679 NISVAIESDMH-MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---------- 727
++A E+ C++ + + Q+ V+ + + L I+++
Sbjct: 3968 TCTIANEAGCESTSCTIDVVDDHLGLQQTGLHVMCERDQNDVELDILVQSPNHLGVTFNF 4027
Query: 728 ----KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783
+T ++PP + PL +V E L V+G P + W + V
Sbjct: 4028 PPVNRTLARQPPYFLLPLSDKVVID-EKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEI 4086
Query: 784 GDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVIT---VEEPTEENAEPPLFINRF 839
I +L+ K + KD+ V +A N +G TS V+T VEE + + P F+
Sbjct: 4087 HFEDGIALLRMKNIKKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSL 4146
Query: 840 QE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
++ T + T+K + V P+P ++ N ++ + I ++ DG +V+ V+
Sbjct: 4147 KDTCTTTDHATLKCI--VVGTPLPDVSCSFNG--VTDNSKI-RSEDG----IVLIQVNDV 4197
Query: 899 IDSG-DYKCVASNSAGKSSHGARVTI------DVEKVTFVKHLQKSYETEEGKTVILECQ 951
+ G +C SN G S+ V I + ++ V + S E +V +
Sbjct: 4198 TEEGIVVECTISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVI 4257
Query: 952 TSHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETST 1008
S + W HN K I G D+ I ++G CI K++ +T+
Sbjct: 4258 ASPEPTLFWKHNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSH--EFTCIAKNEYGQTTV 4315
Query: 1009 MLVVK-----ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
+ V+ E ++ L D V + V + V + W DG+I++
Sbjct: 4316 EIPVEIGLKTENKLTLVKTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILE 4369
Score = 60.9 bits (141), Expect = 1e-08
Identities = 58/218 (26%), Positives = 99/218 (45%), Gaps = 21/218 (9%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHS--ITILKPKKVKDE 800
+G+ V+ + +VV + P I +N+ PV A + G HS +TI +K+ D
Sbjct: 12187 EGDVVVFTIKVVSDDVPLIRMYRNDFPVANFDKMAFEGFTKGSEHSFNVTINDIRKL-DG 12245
Query: 801 GVYTLKAENSEGIAETSAVITVEEP---TEENAE---PPLFINRFQEITVKEKGTIKLVA 854
G +A+N G+ + + ++ V + E+ +E N ++ VKE T KL
Sbjct: 12246 GKLVFEAKNDYGVDKCTILLDVRDSGSFIEDYSEIHRSAEIQNSVGDVQVKEGETAKLTG 12305
Query: 855 RVTRNPVPSITWYRNN---EIISPSETITQNF--DGENIELVITNVDSEIDSGDYKCVAS 909
RV P+P + W +N +++ PS ++ DGE E I N E D DY +
Sbjct: 12306 RVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGE-FEARIANCTFE-DDDDYSLLVE 12363
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
N AG S +V +D + +H + + G+ V+
Sbjct: 12364 NLAGVDSCNFQVFVDCNEYPDDEHFNRRRRLQRGRRVM 12401
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/301 (22%), Positives = 121/301 (40%), Gaps = 24/301 (7%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+TA G P PE+ W+KN ++ + K I + + I E++ +Y I NTA
Sbjct: 15618 ITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMREDDEGEYKIVVKNTA 15677
Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
G SVE + K+ + + P I R + R + T+ + D G + +
Sbjct: 15678 G--SVEHSCKL----TMDQLPEINR-VDRYASTLVF----DKGETVKLRLSFSGRPQPEV 15726
Query: 1712 RWI----KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKTALDV 1766
WI KV + R ++ I+K N I G F+ +++ K A+ +
Sbjct: 15727 IWIDNNGKVIEESRKMK---IEKTVLNTVLTINSIDSQDQGEFALKIKNRCGEDKYAIGI 15783
Query: 1767 P-SXXXXXXXXXXIDNE---SVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXX 1821
+ ++++ SV + W +GGSP+ +Y VE+ ++GK W
Sbjct: 15784 QVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWTKAEVTKQ 15843
Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
+ L +Y+FR+ A N G S P + + + +P+ V S
Sbjct: 15844 AFITLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVSRVVEEPKKKEVKVKEQES 15903
Query: 1882 V 1882
V
Sbjct: 15904 V 15904
Score = 58.8 bits (136), Expect = 4e-08
Identities = 133/587 (22%), Positives = 225/587 (38%), Gaps = 86/587 (14%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F Q + +D + VE + + T V W ++ I P + K D L
Sbjct: 17234 PQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDE-KIDVATTSTSSIL 17292
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PE------IITRLQNQKV 1118
++ S + G ++C++ +E S + +VT+ P P+ ++ LQ
Sbjct: 17293 NLK--SQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALN 17350
Query: 1119 NKGNKATFEIELT-----KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDD 1172
N+ +A +I LT + ++ V WFKD I+ + +L+ D K KL + D
Sbjct: 17351 NESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQD 17410
Query: 1173 AGEYSCEVGN------SKCT-AILTVEE---PSINFTLRLPEFILVPANTDAYLTVEIPD 1222
G+Y C V N S+C A+ V + PS + TL IL N VE
Sbjct: 17411 TGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAIL-GHNITLECKVE-GS 17468
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTC------------- 1268
+V+W K I T + D L I K DD Y C
Sbjct: 17469 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSS 17528
Query: 1269 VLLDAKST-TKLKVEVVEFPPKIVDYEREYR-------IKRGSDVTLLVDYQAFPQPNDE 1320
+++ AK+T T + + + + + R R + TL+ P+P
Sbjct: 17529 MVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVT 17588
Query: 1321 WIVNSKIIKKCK---HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W+ + + I + H + D +S L + V + +GI+ + EN G E V I
Sbjct: 17589 WLKDGREILRTNRIYHHFVTGDGES-HLIAECVVSKTSGIFSCKAENPNGTVIAETQV-I 17646
Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK------ 1431
+ + P + + + D G+ T + V T EWI +
Sbjct: 17647 VQRMKPANQ--LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKI 17704
Query: 1432 NITKTQTS--------IQNLKTNSSYRFRAYAVNEVDISDASE-TTEYYKVIKETKIQS- 1481
N+T + T + LK+ R + + + + + TT+ Y ++ E +
Sbjct: 17705 NLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPA 17764
Query: 1482 --PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P K L++ T E IE + G P P +TWY + KK+ K
Sbjct: 17765 GPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGK 17811
Score = 57.2 bits (132), Expect = 1e-07
Identities = 88/393 (22%), Positives = 140/393 (35%), Gaps = 37/393 (9%)
Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTL 1660
V W K+G L D Y +T+ S ++I + + S +T + ++ G S+ VT+
Sbjct: 15220 VEWKKDGKAL--DASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVKSSEGDEEEVSIAVTV 15277
Query: 1661 KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720
K+ + P I+ + + K + TK E N +K
Sbjct: 15278 KLPEVPKVEAEQSIVEVKVGDVAKLSAKISEPASSVNWTKDDKPIKEDGN---VKAQLSP 15334
Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
I K + ++++ +N G + +E + A P +
Sbjct: 15335 DGTAQLTISKTDSAHSGIYKLNVENDAGKGK-VEIALRIKGAAKGAPGIPTGPIVFDDVT 15393
Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839
S +W E NGG I Y VE K+ + K WK + L T Y ++
Sbjct: 15394 ESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQCGKTKELKFKADGLEEGTDYDVKV 15453
Query: 1840 YARNEIGTSLPY-----TSDDKITIGKTLTPPSQP-----RNFVVSE-----------ST 1878
A N +GT T K GK + S+ + VSE ST
Sbjct: 15454 SAVNTMGTGSALEGKITTLKKKEETGKQKSEKSESDEKKSESDKVSELKQIGKPEYVSST 15513
Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
+ S+ LKWT Y ++ K K +V S I +KE +F
Sbjct: 15514 ATSIALKWTSDNDE-----VTYTVQMKEANSKRPWAVVAKEISECSATIAQLKEGTSYLF 15568
Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971
R+ A+N G ++ T QS +E T S A
Sbjct: 15569 RVIAQNKTGQTV-TSEQSESIECKDTTESKKPA 15600
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 24/204 (11%)
Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENI 1930
V + T S W PE+NGG IT Y +E K K K W + G E + +
Sbjct: 15388 VFDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQC----GKTKELKFKADGL 15443
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV-------------PSPPTAPLEIRM 1977
+E + ++SA NT+G E + L+K S E++
Sbjct: 15444 EEGTDYDVKVSAVNTMGTGSALEGKITTLKKKEETGKQKSEKSESDEKKSESDKVSELKQ 15503
Query: 1978 VGSNIVMTSWGTP---EWDGGAPLLGYNIAIRDV-TKTMWMEVGKVDVNTLKFNIRDLSE 2033
+G ++S T +W + Y + +++ +K W V K +++ I L E
Sbjct: 15504 IGKPEYVSSTATSIALKWTSDNDEVTYTVQMKEANSKRPWAVVAK-EISECSATIAQLKE 15562
Query: 2034 NHTYMIRIYARNEIGLSEPLESDE 2057
+Y+ R+ A+N+ G + E E
Sbjct: 15563 GTSYLFRVIAQNKTGQTVTSEQSE 15586
Score = 56.4 bits (130), Expect = 2e-07
Identities = 50/205 (24%), Positives = 95/205 (46%), Gaps = 11/205 (5%)
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLK--NITTEPNEDIELTCIFGGV--PQP 1511
V E IS+ + ++ V+K K + ++P+ N N + EL+ G + P+P
Sbjct: 4203 VVECTISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEP 4262
Query: 1512 KVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVG 1566
+ W +GK ++ Y E+ + CIA N++G+ VE +G
Sbjct: 4263 TLFWKHNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSHEFTCIAKNEYGQTTVEIPVEIG 4322
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
++ + +T+ + + V D + V EG P E W+++G LE+D + IT +
Sbjct: 4323 LKTENKLTLV-KTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKC 4381
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTA 1651
S +++K L+ + + T E SN++
Sbjct: 4382 ISTLQLK-LEETGTRIITCEVSNSS 4405
Score = 56.4 bits (130), Expect = 2e-07
Identities = 71/365 (19%), Positives = 133/365 (36%), Gaps = 27/365 (7%)
Query: 1313 AFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
A+P + W NS +++ + S D + ASL V D G Y N G A
Sbjct: 18132 AYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVT 18191
Query: 1372 EMNVTI--LDKPSPPGKPNILE----------IDSSSINICWDEPENTGNSTIIYYVVEY 1419
MN+ + +D + G P + +D S + + + + + I + +
Sbjct: 18192 NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKV 18251
Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
+D+ + ++ +I ++ + A N+ I+ + + +
Sbjct: 18252 TIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVAD 18311
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXX 1535
++P V ++P +EL G P P ++W + G+KL K ++
Sbjct: 18312 EAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFIL 18371
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-------KPVITISNEDIKQKHKVGD 1588
Y+ A N G+ + + Q KP S ++ K
Sbjct: 18372 RIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRA 18431
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
E + A G P P W+ NGN+L + + Y IT+ + S + I + + H +Y
Sbjct: 18432 E--LRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTI 18489
Query: 1648 SNTAG 1652
N G
Sbjct: 18490 RNQNG 18494
Score = 56.0 bits (129), Expect = 3e-07
Identities = 85/380 (22%), Positives = 153/380 (40%), Gaps = 40/380 (10%)
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA------ 1098
A ++W R+ + P+ ++Y G L + + DEG Y+C +E +A
Sbjct: 18136 ASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVTNMNL 18195
Query: 1099 EVTVVE------LPPEI-ITRLQN-QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQF 1148
+V+ V+ +PP ++++ +KV G++ EL + +RW ++ I
Sbjct: 18196 QVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVD 18255
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPE 1204
S + L I D +D GEY+ E N ++CT L V + P
Sbjct: 18256 SPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPR 18315
Query: 1205 -FILVP-ANTDAYLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
F P +D ++VE+ + + ++W K + + EK+ + ++ K L I
Sbjct: 18316 VFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIAN 18375
Query: 1258 CTEDDQCEY--TCVLLDAKSTTKLKVEVVE------FPPKIVDYEREYRIKRGSDVTLLV 1309
T D +Y T + ++ +L++ VV+ PK + + + L
Sbjct: 18376 VTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRAELRA 18435
Query: 1310 DYQAFPQPNDEWIVN-SKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P W N +++I +T S D+ S SL I V+ G Y + N G
Sbjct: 18436 SFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNS-SLLINSVDKKHFGEYLCTIRNQNG 18494
Query: 1368 HADVEMNVTILDKPSPPGKP 1387
+ N IL + S P
Sbjct: 18495 --EELANAMILSEGSSAALP 18512
Score = 55.6 bits (128), Expect = 4e-07
Identities = 83/409 (20%), Positives = 154/409 (37%), Gaps = 36/409 (8%)
Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
+ D + + + + + +++ + KP+ IT + ++ L + P+ + DGK
Sbjct: 14039 VCDGVDCSTHLSIQGKPVLKNVSETKPV--ITVDKDDQFSLLVAYDSNPEASFSMTVDGK 14096
Query: 1521 KL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
L ++ ++ Y+ N+ GEV V + P
Sbjct: 14097 DLEFDGRSRIDVVDDGLKLTKRGVSKTDAGEYEVKLKNEFGEVAQKFDVKVNDTPSAPGD 14156
Query: 1577 NEDIKQKHK-VGDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
+K + + EW G VI K + + K + K+ + V+ E
Sbjct: 14157 VSVVKAESDCLHIEWTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLE 14216
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKP 1689
++ + + I A N GT T V + P+ E P + ++ S ++ W
Sbjct: 14217 IETPYIVR--IAAVNKFGTGEFIETKPVQTGSPFQVPTV-EFPPTIDNVTSTSCSLSWPK 14273
Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD-VETYCIQKLNENCEYMFRVIAQNPVG 1748
P++DGG + Y + K E + W K+ + E++ ++ L+ EY F++ A N G
Sbjct: 14274 PIEDGGSPVYGYDVYKRE-NEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAG 14332
Query: 1749 FSEALESEPIVIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
S + K ++ VP +DN+ V +TW K+ G ++ V+
Sbjct: 14333 LRS--NSNVVSKKLTVEGLVPEIILDMPMVKVLDNDKVEVTW----KSDGEK--EFVVQY 14384
Query: 1807 KQEGKK-WKX-------XXXXXXXXARIQKLSINTTYQFRIYARNEIGT 1847
K +G W I L Y FR+ ARN+ GT
Sbjct: 14385 KSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIPYVFRVAARNQHGT 14433
Score = 55.2 bits (127), Expect = 5e-07
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S AP F+ KL G VQ +C + G P+P+I W I P+ ++ + Y +
Sbjct: 1672 SSAAPQAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVY-E 1730
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAG 590
D V L I ED G + C A N AG
Sbjct: 1731 DGVCILRIESTLIEDEGEYCCTASNVAG 1758
Score = 54.8 bits (126), Expect = 6e-07
Identities = 59/260 (22%), Positives = 104/260 (40%), Gaps = 22/260 (8%)
Query: 1804 VEIKQEGK----KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
VE K++GK + +I + +NT+ F ++ G +++++I
Sbjct: 15220 VEWKKDGKALDASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVKSSEG------DEEEVSI 15273
Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTL----KWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
T+ P P+ V +E + V + K + S S + N+ + K +K K
Sbjct: 15274 AVTVKLPEVPK--VEAEQSIVEVKVGDVAKLSAKISEPASSV-NWTKDDKPIKEDGNVKA 15330
Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT-VPSPPTAPLE 1974
+ I I++++ EN G ++R++ A P PT P+
Sbjct: 15331 QLSPDGTAQLTISKTDSAHSGIYKLNVENDAGKG--KVEIALRIKGAAKGAPGIPTGPIV 15388
Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
V + SW PE +GG + GYN+ ++ W + GK LKF L E
Sbjct: 15389 FDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQCGK--TKELKFKADGLEEG 15446
Query: 2035 HTYMIRIYARNEIGLSEPLE 2054
Y +++ A N +G LE
Sbjct: 15447 TDYDVKVSAVNTMGTGSALE 15466
Score = 54.8 bits (126), Expect = 6e-07
Identities = 165/857 (19%), Positives = 306/857 (35%), Gaps = 104/857 (12%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF------RQTAIIKPS 553
KP ++ ++AP F L +G C V G P P + W + + +
Sbjct: 17651 KPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSST 17710
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
D+ VA L V E GT+ C+A N++G A++ L+V LSD +
Sbjct: 17711 TDWTECRFG-KVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLV-GELSDEPAGPPR 17768
Query: 614 XXXXXXXXXXXXADILE------GIP-PTFSKKPKAQYVDEGSDILLE-----CRLVAIP 661
+ +E G P P + + ++EG D+ + +++I
Sbjct: 17769 FVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIK 17828
Query: 662 EPDIAWLFKGEEIVPDENISVAIE-------SDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
+A L G V NI + SD + +V + VA +
Sbjct: 17829 NVSLASL--GMYFVEASNIHGVLRTAGRLNVSDERRKAEPPQFKHVLEPVLAVQPKVAFS 17886
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-NK 773
E + + + P ++ L+ M ++ G S ++ ++ RP + + +K
Sbjct: 17887 EEHPRASSSAATARVKKGAAPMFLQGLEDMDLKAGASAAVAGKLGRKLRPHRSTTNDADK 17946
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
KAL S+ + +P+ D + E++ A + + P
Sbjct: 17947 LAKAL-------AQSLRLDEPRASIDS-----RPESAANAALDEVRAAINSRNKRVCRPK 17994
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
+ ++E +++L ++ NP+P + W + I+ + DG+ L +
Sbjct: 17995 FMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVH 18054
Query: 894 NVDSEIDSGDYKCVASNSAG-------------KSSHGARVT-----IDVEKVTFVKHLQ 935
+V S D G Y C A+N+ G K A+V + + F++ L
Sbjct: 18055 HV-STFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLP 18113
Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXX 992
+ +++ +EC S S W N + + D + +G
Sbjct: 18114 GRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG 18173
Query: 993 DVGVIKCIVKDQ----ETSTMLVVKETIP---EFIRKLQDFE-VK--EKDVAILEVEI-- 1040
D G C ++ T+ L V P E I L FE +K K V VE+
Sbjct: 18174 DEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAA 18233
Query: 1041 ----NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES- 1095
SE + W R+ I + + + + ++ L I + D GEY+ +++S
Sbjct: 18234 ELVQASEPLQIRWLRNKVTIVDSPS-FSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSG 18292
Query: 1096 ---CTAEV-------TVVELPPEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGS 1144
CT ++ +V + P + + + G + + D ++ W K G
Sbjct: 18293 IARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQ 18352
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-- 1202
++ + +G K L+I + DAG+Y N A +E + T +
Sbjct: 18353 KLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGA 18412
Query: 1203 -PEFILVPANTD------AYLTVEIPDETLDV-TW-YKKKSVIEDTEKFTLISDVKKRTL 1253
P+F P + A L W Y +I+ + +T+ S +L
Sbjct: 18413 KPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSL 18472
Query: 1254 IIRKCTEDDQCEYTCVL 1270
+I + EY C +
Sbjct: 18473 LINSVDKKHFGEYLCTI 18489
Score = 54.4 bits (125), Expect = 8e-07
Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 3/107 (2%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP ++ ++P P ++ EC G+P P+ W++ I P+ + ++ +++ L
Sbjct: 14450 APRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNEGSMSAL 14509
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMT 612
+I E+ ED G + + +N G A S E+ V A + SE+T
Sbjct: 14510 IIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELT 14556
Score = 54.4 bits (125), Expect = 8e-07
Identities = 99/402 (24%), Positives = 162/402 (40%), Gaps = 36/402 (8%)
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNR-WIKVADVDRDVETYCIQKLNENCEYMFR 1740
S+ ++W D E+T Y ++ E ++ R W VA + I +L E Y+FR
Sbjct: 15516 SIALKWTSDND----EVT-YTVQMKEANSKRPWAVVAKEISECSA-TIAQLKEGTSYLFR 15569
Query: 1741 VIAQNPVGFSEALE-SEPIVIK--TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG- 1796
VIAQN G + E SE I K T P+ + N IT +E G
Sbjct: 15570 VIAQNKTGQTVTSEQSESIECKDTTESKKPAFTNAPTDLTAVKNGKTKIT---AEFTGHP 15626
Query: 1797 SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
+P I + K+ GK+ I ++ + +++I +N G S+ ++
Sbjct: 15627 APEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMREDDEGEYKIVVKNTAG-SVEHSC- 15684
Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF-KTVKGKSWT 1913
K+T+ + L ++ + + + T+K S P +I K ++
Sbjct: 15685 -KLTMDQ-LPEINRVDRYASTLVFDKGETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKM 15742
Query: 1914 KIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
KI TV +V I +I +D+ F + +N G + +++ P P
Sbjct: 15743 KIEKTVLNTVLT--INSIDSQDQGEFALKIKNRCGED--KYAIGIQVTDRPAAPGKPA-- 15796
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF-NIRDL 2031
+E + V S V W P DGG+P+ Y + + W K +V F + +L
Sbjct: 15797 VEDQNVDS--VRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWT---KAEVTKQAFITLFNL 15851
Query: 2032 SENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
+Y R+ A N G SEP SDE V+ S EEP
Sbjct: 15852 VPGESYRFRVRADNTFGQSEP--SDESELVVVKNVSRVVEEP 15891
Score = 54.0 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 79/204 (38%), Gaps = 20/204 (9%)
Query: 1482 PTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGK---KLKTAKATYENR-XXXX 1536
P V +PL + T TE N ++ L G P P + WY DGK + +T + ++ R
Sbjct: 16815 PVVTRPLADATVTEGNREL-LEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLK 16873
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ---------QKPVITISNEDIKQKHKVG 1587
Y C N G VET +V ++ Q P +D+ K G
Sbjct: 16874 IYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK-TAG 16932
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK---EKTSVIRIKELKRSHSSKYT 1644
+ T P +V+W NG L+ K N T+ + T+ + I+ + YT
Sbjct: 16933 ETATFTCQSYANPAAQVVWLHNGKALQQTKS-NYKTRLFDDNTATLVIENVTDELCGTYT 16991
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSK 1668
A+N G L + +K
Sbjct: 16992 AVANNQFGDVHTSAQLTISGSEAK 17015
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/196 (25%), Positives = 87/196 (44%), Gaps = 17/196 (8%)
Query: 631 GIPPTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G + + PK+ V + S+++++C+ + P D W G ++PDE +++ +
Sbjct: 8762 GTGQSIIEHPKSHAVGQMNSEVIIKCK-TSQPISDAKWFCNGMVLLPDEQVNMTVTG--- 8817
Query: 690 MYC-SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
C +VL++ +G Y V+ G S P +L PP ++ L I Q
Sbjct: 8818 --CEAVLRLVKFLPQNKGNYHVLIDGSIG--SQPAIL----SGPVPPVILNKLTKPITHQ 8869
Query: 749 -GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLK 806
G+S +G P P + N +PV + K + + ++ PK K D G YT+
Sbjct: 8870 AGKSFTYKFNFMGAPAPRLRVLSNGEPV-SFDVKYEIYDNIASLYIPKMSKRDGGEYTVV 8928
Query: 807 AENSEGIAETSAVITV 822
EN G E+ IT+
Sbjct: 8929 LENKYGKDESDLHITM 8944
Score = 53.2 bits (122), Expect = 2e-06
Identities = 89/412 (21%), Positives = 155/412 (37%), Gaps = 43/412 (10%)
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKL 1360
G + L + + W + + I+ + S D KS L V++ D G Y+
Sbjct: 17357 GQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRC 17416
Query: 1361 RLENNCGHADVEMNVTILD--KPSPPGKPNILEIDSSSI---NICWDEPENTGNSTIIYY 1415
+ N G+A+ E NV + D K P L DS++I NI + + + +
Sbjct: 17417 VVTNKYGYAESECNVAVEDVTKFIAPSFSATLS-DSTAILGHNITLECKVEGSPAPEVSW 17475
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
+ + I TT I + K S Y + ++ T+ + K
Sbjct: 17476 TKDGERISTTRRIRQTQDENGNCKLSISKAESD-DMGVYVCSATSVAGVDSTSSMVMIAK 17534
Query: 1476 ETKIQSPTV---------EKP----LKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGK 1520
T S V EKP E NE + T I V P+P VTW +DG+
Sbjct: 17535 TTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGR 17594
Query: 1521 K-LKTAK-----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVI 1573
+ L+T + T + + C A N +G V V +Q+ KP
Sbjct: 17595 EILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPAN 17654
Query: 1574 TISNEDIKQKHKVGDEWLV-------TAVIEGIPPPEVIWY---KNGNKL---ENDKEYN 1620
++N K + D +V + + G P P + W +G+K+ + ++
Sbjct: 17655 QLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWT 17714
Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
K + ++ + + R Y A+N++G ++ + L V + +P GP
Sbjct: 17715 ECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGP 17766
Score = 52.4 bits (120), Expect = 3e-06
Identities = 70/302 (23%), Positives = 124/302 (41%), Gaps = 45/302 (14%)
Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGE 1086
V E ++ VE++ V W +D + + + + + +G+ R + I NT V D+G
Sbjct: 3014 VMEGQPTVITVELDDPNVIVNWLKDRRPLHENERIRLETDGQGNHRVI-IPNTCVGDQGT 3072
Query: 1087 YSCILRDESCTAEVTVVELPPE----IITR--------LQNQKVNKGNKATFEIELTKGD 1134
Y + ES + V E E +I +Q V G+ AT EL + +
Sbjct: 3073 YLALTSSESVAITLVVEERIEEKEVMVIASGTESEEDDVQEYLVPPGSTATIACELEECE 3132
Query: 1135 AL--VRWFKDGSEIQF----SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
+RW +DG +I+F + H+Q +G K L ++D D+G Y E +C
Sbjct: 3133 LKRSIRWLRDGKDIRFEQGKTEHVQ---NGLKHYLVVHDATSLDSGLYKTERSEEQC--- 3186
Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTL--I 1245
E ++P A + + + + W K ++I D +F +
Sbjct: 3187 ---------------EETIIPRGVVATIQCQTSEPQESIQWSKDGNIIPSDISRFEFRSL 3231
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305
+ + ++I + D Y+ VL++ KS+ K+ VVE E E + DV
Sbjct: 3232 DNNQSHEMVISNISWSDAGVYS-VLINGKSSFVSKIVVVESELITQSVEEEPEAEPEIDV 3290
Query: 1306 TL 1307
+L
Sbjct: 3291 SL 3292
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 10/168 (5%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
G+ +SAQV ++ W K+ K + A T + S + V GV+T K +
Sbjct: 15204 GKEGEISAQVA-ETGVSVEWKKDGKALDASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVK 15262
Query: 809 NSEGIAE-TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
+SEG E S +TV+ P E I + VK KL A+++ P S+ W
Sbjct: 15263 SSEGDEEEVSIAVTVKLPEVPKVEAEQSI-----VEVKVGDVAKLSAKISE-PASSVNWT 15316
Query: 868 RNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGK 914
++++ I + + +L I+ DS SG YK N AGK
Sbjct: 15317 KDDKPIKEDGNVKAQLSPDGTAQLTISKTDSA-HSGIYKLNVENDAGK 15363
Score = 49.2 bits (112), Expect = 3e-05
Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
D G ++L C + P + W G EI P N ++ +E+D + L+I N K
Sbjct: 14651 DFGETMVLFCE-TSKPVRKVKWFKNGVEIWPQMNKAI-MENDGKR--ATLEIKNFDKHDI 14706
Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
G YT +E A +V ++ P ++ + + V G + + G P PT
Sbjct: 14707 GAYTASVSEKETSAPAKLVFEVAPNLIIPTEIRD---GVTVHAGNEFDFAVEFSGFPIPT 14763
Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
I N P+KA+ ++ D +K + + G + AE+ G
Sbjct: 14764 IHLTNNGTPLKAIAVVTEYDDSVSVRMKDVTLDNSGTVRVIAESPLG 14810
Score = 49.2 bits (112), Expect = 3e-05
Identities = 22/69 (31%), Positives = 39/69 (56%)
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
A + G P P + W K G KL N+++Y + + ++RI + R+ + KY + A N +G
Sbjct: 18335 AKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 18394
Query: 1654 SSVEVTLKV 1662
++ E+ L V
Sbjct: 18395 ANAELELTV 18403
Score = 48.4 bits (110), Expect = 6e-05
Identities = 22/78 (28%), Positives = 43/78 (55%)
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
++G+ + +I G+P PE+ W +G+ + + EY+I ++ ++RI+ +Y
Sbjct: 1691 RIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYC 1750
Query: 1645 IEASNTAGTSSVEVTLKV 1662
ASN AGT+ + LK+
Sbjct: 1751 CTASNVAGTTFSKCYLKL 1768
Score = 48.0 bits (109), Expect = 7e-05
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F +K + G + L+C + +P+P+I W G+ IVP++ S+ E + C
Sbjct: 1679 PKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGV---C- 1734
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
+L+I + EG Y A N G LK+ + + ++ L +
Sbjct: 1735 ILRIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDDAVDLLRQLSEI 1785
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/311 (20%), Positives = 115/311 (36%), Gaps = 24/311 (7%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL---VR 1138
H+E E S ES + + LPP+ I L + N + T V
Sbjct: 923 HEEAEIS-----ESVLTDDVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVS 977
Query: 1139 WFKDGSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCE------VGNSKCTAILT 1190
W KDG +I + ++ DG Q L I D+G Y+C V NS C LT
Sbjct: 978 WQKDGMDIYENEKYEVMQFADGA-QILTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELT 1036
Query: 1191 VEEPSINFTLRLPEFI----LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLIS 1246
+ S + E + D + V + +E +K+ E+ + ++
Sbjct: 1037 ISAESSPESFEKVEITPPEEVKETGIDDDIEVILKEEVSGTAQIEKRE--EEFKLLVKVA 1094
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
D TL+ E ++ ++E + P+ EY +K +
Sbjct: 1095 DQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQ-EPRFETSTDEYHVKENGTIK 1153
Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
+ P P EW + ++ ++ ++ ++++ +K V+ G Y LR N
Sbjct: 1154 MAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCH 1213
Query: 1367 GHADVEMNVTI 1377
G + + M +T+
Sbjct: 1214 GESILPMKLTV 1224
Score = 46.8 bits (106), Expect = 2e-04
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
+ Q P TIS + K DE+ + G P P V WYK ++ D++ ++ T
Sbjct: 17230 VGQAPQFTISPQS-KIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTST 17288
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+S++ +K + + + IE N G +S + +++KP+
Sbjct: 17289 SSILNLKSQEENGTFNCLIE--NELGQASASCQVTIFNKPA 17327
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 1481 SPTVEKPLKNITTEPNEDIE-LTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXX 1534
+P+V+K L++I + I L+C GVP PKV WY+D K+L Y E
Sbjct: 16252 APSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAE 16311
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
Y C A ND G + T + ++
Sbjct: 16312 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVK 16345
Score = 46.0 bits (104), Expect = 3e-04
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
PP FI + V TI LV V +P W+ N + + Q G NI +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVGHGINISRL 148
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
S + G YKCV N AG S+ +T++ ++ +HL S E
Sbjct: 149 KV---SRPEQGVYKCVTRNPAGVSTSYGYITVNADR----EHLSSSKE 189
Score = 45.6 bits (103), Expect = 4e-04
Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F +V E I + + P P + W F E++ +N+S+ E+ S
Sbjct: 1135 PRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGT----S 1190
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG---E 750
+ + NV+K Q G Y + A N GE+ LP+ L + E + + ++V Q E
Sbjct: 1191 AIILKNVQKRQGGNYFLRAHNCHGESILPMKLTVDPIEAVTHVLETSIPKVVVEQDAKEE 1250
Query: 751 SVILSAQVV 759
V +A+++
Sbjct: 1251 EVRRAAEII 1259
Score = 45.6 bits (103), Expect = 4e-04
Identities = 86/421 (20%), Positives = 178/421 (42%), Gaps = 53/421 (12%)
Query: 831 EPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+PP F+ + + + EK T+K V V P+ + W + +++ + +F+
Sbjct: 4037 QPPYFLLPLSDKVVIDEKCTLKCV--VMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIAL 4094
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---------DVEKVTFVKHLQKSYET 940
L + N+ D +C A N GK + +T D++K +FV L+ + T
Sbjct: 4095 LRMKNIKK--DKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTT 4152
Query: 941 EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
+ T L+C V T +G+ I+ + V++C
Sbjct: 4153 TDHAT--LKCIV---VGTPLPDVSCSFNGVTDNSKIRSEDGIVLIQVNDVTEEGIVVECT 4207
Query: 1001 VKDQETST-----MLVVKETIPEFIRKLQDFEV-----KEKDVAILEVEINSETADVVWE 1050
+ ++ S+ + ++K+ + R + F E+++++ I S + W+
Sbjct: 4208 ISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWK 4267
Query: 1051 RDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
+G+ I+ + Y FE I K++ H E++CI ++E T VE+P EI
Sbjct: 4268 HNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSH---EFTCIAKNEYGQ---TTVEIPVEI 4321
Query: 1110 ITRLQNQKV---NKGNKATFE--IEL---TKGDALV--RWFKDGSEIQFSNHIQLTIDGK 1159
+ +N+ + A + ++L +GD + +WF+DG ++ + ++T+D
Sbjct: 4322 GLKTENKLTLVKTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKC 4381
Query: 1160 KQKLKIYDCDLDDAGE--YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
L++ L++ G +CEV NS + ++ T + +F++ N+ +L
Sbjct: 4382 ISTLQL---KLEETGTRIITCEVSNSSSKVNASCNVERVHNT--VSDFVMTNDNSTRFLA 4436
Query: 1218 V 1218
V
Sbjct: 4437 V 4437
Score = 44.8 bits (101), Expect = 7e-04
Identities = 47/213 (22%), Positives = 84/213 (39%), Gaps = 23/213 (10%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP+ I+ +K+ V +++ L +V +P W N K V + H I I +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVG-HGINISR 147
Query: 794 PKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENA-----------------EPPLF 835
K + ++GVY N G++ + ITV E + + P F
Sbjct: 148 LKVSRPEQGVYKCVTRNPAGVSTSYGYITVNADREHLSSSKEDMRLQRQHSVTYHQAPRF 207
Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
+ + + V + + V NP +W+ N + S + F ++ +
Sbjct: 208 LTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMF-SPDVNRSVVRF 266
Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
+ +G+YK VASN G + V D++KV
Sbjct: 267 SIPV-AGEYKVVASNVHGSAMSCGHV--DIQKV 296
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/180 (21%), Positives = 71/180 (39%), Gaps = 9/180 (5%)
Query: 1023 LQDFEVKEKDVAILEVEINS---ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ + VK + A + E+N+ + + W I ++D + L IR+
Sbjct: 2911 IPSYVVKLESTATITCELNNYLPKNCTIDWYCGKTKIIIDHEQFDRISHDLLEVLIIRSV 2970
Query: 1080 SVHDEGEYSCILRDESCTAEVTVVE-----LPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ YS + ++ +VE I+TR + Q V +G +EL +
Sbjct: 2971 EAINGNLYSLKINEDLFPVAYLIVENTNLTTSANILTRPETQFVMEGQPTVITVELDDPN 3030
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGK-KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+V W KD + + I+L DG+ ++ I + + D G Y + L VEE
Sbjct: 3031 VIVNWLKDRRPLHENERIRLETDGQGNHRVIIPNTCVGDQGTYLALTSSESVAITLVVEE 3090
Score = 43.2 bits (97), Expect = 0.002
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVN---EVDISDASE 1466
TI + + +++ + E IS+K N+ N+ + A N +V+ S
Sbjct: 3819 TISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVETSCEIV 3878
Query: 1467 TTEYYKVIKETKIQS---PTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
+ VI ++ I S P PL + +T N+ I + C F G P P W +DG L
Sbjct: 3879 AADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLL 3938
Query: 1523 KTAK---ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
K T + Y C N+ G TSC + +
Sbjct: 3939 DLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDV 3986
Score = 43.2 bits (97), Expect = 0.002
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 9/136 (6%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
S +KI V G +T + EG E + I + +K E P+V + V+ G+
Sbjct: 15242 STVKIPIVDVNTSGVFTCKVKSSEGDEEEVSIAVTVKL--PEVPKVEAEQSIVEVKVGDV 15299
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
LSA++ P ++ W K++KP+K S T +TI K G+Y L
Sbjct: 15300 AKLSAKI-SEPASSVNWTKDDKPIKEDGNVKAQLSPDGTAQLTISKTDSA-HSGIYKLNV 15357
Query: 808 ENSEGIAETSAVITVE 823
EN G + + ++
Sbjct: 15358 ENDAGKGKVEIALRIK 15373
Score = 43.2 bits (97), Expect = 0.002
Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 8/189 (4%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
D E P F+ P + + P P+I W +EI + + +
Sbjct: 15592 DTTESKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIA 15651
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ L I +++ EG Y +V N G L + E +V +++
Sbjct: 15652 G----ATSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQ-LPEINRVDRYASTLVF 15706
Query: 747 RQGESVILSAQVVGNPRPTITWCKNN-KPVKALPTKSDGDTHSITILKPKKV--KDEGVY 803
+GE+V L G P+P + W NN K ++ T T+L + +D+G +
Sbjct: 15707 DKGETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEF 15766
Query: 804 TLKAENSEG 812
LK +N G
Sbjct: 15767 ALKIKNRCG 15775
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ E + P F H + T++ + G+P P + W+ ++ SQ+ M
Sbjct: 1124 EEDNQIEATQEPRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSM 1183
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
YY + + ++++ V G + A N G + +L V+
Sbjct: 1184 YY-EAGTSAIILKNVQKRQGGNYFLRAHNCHGESILPMKLTVD 1225
Score = 42.3 bits (95), Expect = 0.004
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 1780 DNESVYITW-FPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
+ E+V +TW P+E NG S + +Y VE K +G +W+ A + L T Y F
Sbjct: 10471 ERETVTLTWSLPTELNG-SNVNEYLVERKTVDGGRWRHACTVTDSRAVVDGLFSGTEYVF 10529
Query: 1838 RIYARNEIGTSLP 1850
R+ A N G S P
Sbjct: 10530 RVVAVNGAGQSAP 10542
Score = 42.3 bits (95), Expect = 0.004
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
++G+P P+V WYK+ +L +Y+ E + + +K + S + KYT A+N G+
Sbjct: 16277 VDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATNDLGSI 16336
Query: 1655 SVEVTLKV 1662
L V
Sbjct: 16337 MTHAKLSV 16344
Score = 42.3 bits (95), Expect = 0.004
Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1564 VVG--IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
VVG IQ+ PV+T D G+ L+ ++G P P + WY +G + +
Sbjct: 16806 VVGGEIQRPPVVTRPLADATVTE--GNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRT 16863
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
+ + ++I E H+ +Y + SN G + V + P E
Sbjct: 16864 YFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETR-AIVVVEAPDAAE 16911
Score = 41.1 bits (92), Expect = 0.008
Identities = 54/256 (21%), Positives = 107/256 (41%), Gaps = 26/256 (10%)
Query: 996 VIKCIVKDQETSTMLVVKETIPE--FIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
V K + +++ T+ VKE + + + K+QD E L+ ++E+ E+
Sbjct: 15082 VKKKVAENKGEETLQEVKEKLKKGKAVEKVQD----ESRRGSLQASSDNESVTTTSEKRS 15137
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRL 1113
E K ++ EK+ L + + ++ E ++ + + V ++ + + +
Sbjct: 15138 EAELEKNSEKSAEKKSTSADLEAADKAETEKSETG---KETTEKKKKVVKKVAKKGLVKA 15194
Query: 1114 QNQKVN--KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
K+ G + ++ + V W KDG + S +T G +KI D++
Sbjct: 15195 DKSKIELTAGKEGEISAQVAETGVSVEWKKDGKALDAS--YTVTSTGGVSTVKIPIVDVN 15252
Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD---------AYLTVEIPD 1222
+G ++C+V +S+ EE SI T++LPE V A A L+ +I +
Sbjct: 15253 TSGVFTCKVKSSEGDE----EEVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISE 15308
Query: 1223 ETLDVTWYKKKSVIED 1238
V W K I++
Sbjct: 15309 PASSVNWTKDDKPIKE 15324
Score = 41.1 bits (92), Expect = 0.008
Identities = 51/220 (23%), Positives = 86/220 (39%), Gaps = 15/220 (6%)
Query: 894 NVDSEIDSGDYKCVASNSAGKSS--HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
+ +++++ D + GK + +V V K VK + E GK + Q
Sbjct: 15153 STSADLEAADKAETEKSETGKETTEKKKKVVKKVAKKGLVKADKSKIELTAGKEGEISAQ 15212
Query: 952 TSHT-VSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVK-----DQ 1004
+ T VS +W KK+ +D + G GV C VK ++
Sbjct: 15213 VAETGVSVEW---KKDGKALDASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVKSSEGDEE 15269
Query: 1005 ETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN-K 1062
E S + VK +P+ + EVK DVA L +I+ + V W +D + IK N K
Sbjct: 15270 EVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISEPASSVNWTKDDKPIKEDGNVK 15329
Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
G + + S H G Y + +++ +V +
Sbjct: 15330 AQLSPDGTAQLTISKTDSAH-SGIYKLNVENDAGKGKVEI 15368
Score = 40.7 bits (91), Expect = 0.011
Identities = 68/301 (22%), Positives = 120/301 (39%), Gaps = 29/301 (9%)
Query: 117 GSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQN 176
G +K E + K+ E+ T + D ++E ESK V + P+
Sbjct: 13359 GKLKIEEESAAKSKQTVEEQAKLDAQTKAKTAEKQTKLEKDEKSTKESESKETVDEKPKK 13418
Query: 177 IIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIE 236
+ + K+ E+S+ I++ SE V E P + ET + + K+ K T K +
Sbjct: 13419 KVLKKKT-----EKSDSSISQKSETSKTVVESAG-PSESETQKVADAARKQ-KETDEK-Q 13470
Query: 237 RKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPES 296
+ E E++ + A+ E K K + ++K T S
Sbjct: 13471 KLEAEITAKKSADE------KSKLEAESKLKKAAEVEAAKKQK-EKDEQLKLDTE--AAS 13521
Query: 297 IKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKL--------PDVEKTELEQPLFSY 348
K + KQ+ I +A K +K++ +L D EK +LE+
Sbjct: 13522 KKAAAEKLELEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKA 13581
Query: 349 EDI--VESKKDENEIIQEKQTLEELPKEDVPEQ--YTITPRKSSAQKIDEIVDEVTIKKR 404
+I +E +K++ ++ QE+ LE+ K+ +Q + T K + + E VDE KK
Sbjct: 13582 AEIALIEIQKEQEKLAQEQSRLEDEAKKSAEKQKLESETKSKQTEEAPKESVDEKPKKKV 13641
Query: 405 L 405
L
Sbjct: 13642 L 13642
Score = 40.7 bits (91), Expect = 0.011
Identities = 40/208 (19%), Positives = 79/208 (37%), Gaps = 14/208 (6%)
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--- 1529
VI+E P L++ + E L +P+P V WY +G+ + + Y
Sbjct: 16374 VIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRK 16433
Query: 1530 --ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVITISNEDIKQ 1582
+ R +K + N GE E+ + + Q P D+K
Sbjct: 16434 HDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKC 16493
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHS 1640
D + I+ P PE+ W++N +++E+ + + + + + + I + S
Sbjct: 16494 SES--DILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDS 16551
Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
+Y A N G + +++ + SK
Sbjct: 16552 GEYKCVAKNKIGKAHTVCCVRIEELLSK 16579
Score = 39.1 bits (87), Expect = 0.034
Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 10/198 (5%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRX-XX 1535
Q+P + L N E ++L C+ G+PQP++ W DG + YE+
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
Y C A N G + C + + + + + K+ D L T
Sbjct: 1737 RIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDDAVDLLRQLSEIKIIDPTLSTGY 1796
Query: 1596 -IEGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTAG 1652
+ I E ++ N L DKE IT + R + +R S++ T++ +
Sbjct: 1797 PMSMISDEENTSHQLLSNVLLTDKEVPITATYNEDLSRAESFRRFFESAETTVKVTELYQ 1856
Query: 1653 TSSVEVTLKVYDKPSKPE 1670
SVE + +P K E
Sbjct: 1857 GESVEAQ---FQQPEKRE 1871
Score = 39.1 bits (87), Expect = 0.034
Identities = 43/225 (19%), Positives = 86/225 (38%), Gaps = 22/225 (9%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWF 1140
+DE E S I D + + + P RL + +K T E+ + + W
Sbjct: 3765 YDEDECSTIA-DTITSLSSSPLYTAPVFTERLPSSACFANSKLTLEVMFSGVPQPTISWL 3823
Query: 1141 KDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILT--- 1190
D E + I + + ++ ++ D + G C N + C +
Sbjct: 3824 IDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEI 3883
Query: 1191 --VEEPSI------NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF 1242
+ + SI +F + LPE + N + + + L ++K V+ D +K+
Sbjct: 3884 SVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKY 3943
Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK--STTKLKVEVVE 1285
+ ++ L I + DD+ YTC + + +T ++VV+
Sbjct: 3944 QVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDVVD 3988
Score = 39.1 bits (87), Expect = 0.034
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 523 DGSTVQFECQVEGYPRPQITWF---RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
+G T + +V+G+P P++ W ++ ++ PS +Q+ Y D I ED
Sbjct: 12297 EGETAKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCTFEDDD 12356
Query: 580 TFTCVAKNAAGFASSTTELIVE 601
++ + +N AG S ++ V+
Sbjct: 12357 DYSLLVENLAGVDSCNFQVFVD 12378
Score = 38.7 bits (86), Expect = 0.045
Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
+ P+ + L + R GE V L + G P+P I W + P+ S + IL
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 793 KPKK--VKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
+ + ++DEG Y A N G + + + E ++
Sbjct: 1737 RIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDD 1774
Score = 38.3 bits (85), Expect = 0.059
Identities = 38/174 (21%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798
++ V +G+ +++ ++ +P + W K+ +P+ + + ++DG + I+ V
Sbjct: 3010 ETQFVMEGQPTVITVEL-DDPNVIVNWLKDRRPLHENERIRLETDGQGNHRVIIPNTCVG 3068
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR------FQEITVKEKGTIKL 852
D+G Y L +SE +A T + VEE EE + QE V T +
Sbjct: 3069 DQGTY-LALTSSESVAIT---LVVEERIEEKEVMVIASGTESEEDDVQEYLVPPGSTATI 3124
Query: 853 VARVTRNPVP-SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
+ + SI W R+ + I + T++ ++ + + +DSG YK
Sbjct: 3125 ACELEECELKRSIRWLRDGKDIRFEQGKTEHVQNGLKHYLVVHDATSLDSGLYK 3178
Score = 37.9 bits (84), Expect = 0.078
Identities = 20/71 (28%), Positives = 34/71 (47%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+ A I G P P + WY KL+ + ++ + TS I +K +++ Y + A N
Sbjct: 1154 MAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCH 1213
Query: 1652 GTSSVEVTLKV 1662
G S + + L V
Sbjct: 1214 GESILPMKLTV 1224
Score = 37.5 bits (83), Expect = 0.10
Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD---ENISVAIESDM 688
IPP F K EG ++++ + PEP + + ++ +++ D + + V E +M
Sbjct: 12438 IPPRFDKILSDHDAIEGENVVMMVETLGEPEPQVRF-YRDGKLIDDGSGDRMEVRHEDEM 12496
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
+ +LK ++ K +E Y A+N GEA
Sbjct: 12497 RKHWLILK--DICKDEEAEYACQAINVAGEA 12525
Score = 37.1 bits (82), Expect = 0.14
Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 19/217 (8%)
Query: 1187 AILTVEEPSINFTLRL---PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
A L VE ++ + + PE V +TVE+ D + V W K + + + E+
Sbjct: 2990 AYLIVENTNLTTSANILTRPETQFVMEGQPTVITVELDDPNVIVNWLKDRRPLHENERIR 3049
Query: 1244 LISDVK--KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV---------D 1292
L +D + R +I C D ++ + T + E +E +V D
Sbjct: 3050 LETDGQGNHRVIIPNTCVGDQGTYLALTSSESVAITLVVEERIEEKEVMVIASGTESEED 3109
Query: 1293 YEREYRIKRGSDVTLLVDYQAFP-QPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKV 1350
+EY + GS T+ + + + + W+ + K I+ + T+ + L +
Sbjct: 3110 DVQEYLVPPGSTATIACELEECELKRSIRWLRDGKDIRFEQGKTEHVQNGLKHYLVVHDA 3169
Query: 1351 ENTDAGIYKL-RLENNCGHADVEMNV--TILDKPSPP 1384
+ D+G+YK R E C + V TI + S P
Sbjct: 3170 TSLDSGLYKTERSEEQCEETIIPRGVVATIQCQTSEP 3206
Score = 37.1 bits (82), Expect = 0.14
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Query: 322 KVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDE--NEIIQEKQTLEELPKE--DVP 377
K +K+ +PP +K E+ S E ++ESKK E I E+Q ++ E VP
Sbjct: 12786 KSRKKEGLPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKISEQQPSDKNKSEVVGVP 12845
Query: 378 EQYTITPRKSSAQKIDEIVDEVTIKKR 404
E+ K +I+E+ + TIKK+
Sbjct: 12846 EKAAGPETKKDVSEIEEVPKKKTIKKK 12872
Score = 36.7 bits (81), Expect = 0.18
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 3/114 (2%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
EPP+ + L S+I V E ++LS V P W N VK + D H+ +
Sbjct: 404 EPPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKKSQSVVLLDEHNKST 463
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA--EPPLFINRFQEIT 843
L +G Y + A N G + +T ++ A EPP + +T
Sbjct: 464 LVLHPPVKQGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVT 517
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 806 KAENSEGIA-ETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +N +GI E ++ TE +A P P F+ + + ++L + P P
Sbjct: 1649 EGDNRQGIEDEPFTEVSQSLATESSAAPQAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQP 1708
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
I W + + I P++ + ++ L I + E D G+Y C ASN AG
Sbjct: 1709 EIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIE-DEGEYCCTASNVAG 1758
Score = 36.7 bits (81), Expect = 0.18
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKAL--PTKSDGDTHSITILKPK----KVKD 799
V++GE+ L+ +V G P P + W KN K + + TK D HS + + +D
Sbjct: 12295 VKEGETAKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCTFED 12354
Query: 800 EGVYTLKAENSEGIAETSAVITVE 823
+ Y+L EN G+ + + V+
Sbjct: 12355 DDDYSLLVENLAGVDSCNFQVFVD 12378
Score = 36.7 bits (81), Expect = 0.18
Identities = 25/121 (20%), Positives = 54/121 (44%), Gaps = 5/121 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEE--QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQIT 542
+K+ +I ++ P + Q + P F + L +G V + G P PQ+
Sbjct: 12413 KKRKKRRIKRVVERRNPNAPRLTQLIPPRFDKILSDHDAIEGENVVMMVETLGEPEPQVR 12472
Query: 543 WFRQTAIIKPSQDFQM---YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
++R +I +M + D+ L+++++ ++ + C A N AG A ++++
Sbjct: 12473 FYRDGKLIDDGSGDRMEVRHEDEMRKHWLILKDICKDEEAEYACQAINVAGEAWCFSDVV 12532
Query: 600 V 600
V
Sbjct: 12533 V 12533
Score = 36.3 bits (80), Expect = 0.24
Identities = 44/194 (22%), Positives = 79/194 (40%), Gaps = 22/194 (11%)
Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
+E L C+ G+P V W DG + + +E+ +C A
Sbjct: 4052 DEKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALLRMKNIKKDKSVVQCEA 4111
Query: 1553 FNDHGEVETSCVV---GIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
N G+V TSCV+ G++ QKP +S +K D + ++ G P P
Sbjct: 4112 INCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLS---LKDTCTTTDHATLKCIVVGTPLP 4168
Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+V NG +N K I +++ +I++ ++ SN G+S+ +K+
Sbjct: 4169 DVSCSFNG-VTDNSK---IRSEDGIVLIQVNDV-TEEGIVVECTISNETGSSTSNCVVKI 4223
Query: 1663 YDKPSKP-EGPVIM 1675
+ K + P+I+
Sbjct: 4224 IKQEEKNYQRPIIV 4237
Score = 36.3 bits (80), Expect = 0.24
Identities = 43/209 (20%), Positives = 83/209 (39%), Gaps = 9/209 (4%)
Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
T + E++ D + + G SH + ++ V FVK+L + +EG+ V +
Sbjct: 13929 TLIIDEVEPTDSGMEITATCGTESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTL 13988
Query: 953 SHTVSTK---WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM 1009
+H + W + K + I G D G K + + ST
Sbjct: 13989 NHPIDISKVVWLKDGKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTH 14048
Query: 1010 LVVK-ETIPEFIRKLQDFEVKEKD--VAILEVEINSETADVVWERDGEIIK-PKKNKYDF 1065
L ++ + + + + + + +KD ++L ++ A DG+ ++ +++ D
Sbjct: 14049 LSIQGKPVLKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDV 14108
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
G KL R S D GEY L++E
Sbjct: 14109 VDDG--LKLTKRGVSKTDAGEYEVKLKNE 14135
Score = 35.9 bits (79), Expect = 0.32
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 3/137 (2%)
Query: 1287 PPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
PPK V + + L VD QA P W VN +KK + +D + S
Sbjct: 405 PPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKK-SQSVVLLDEHNKS- 462
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
T+ G YK+ N+ G V VT + + +I S++ + E
Sbjct: 463 TLVLHPPVKQGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVTCSHEE 522
Query: 1406 NTGNSTIIYYVVEYQEI 1422
+ G+ + + V QE+
Sbjct: 523 DVGSHSSLQTVRRIQEM 539
Score = 35.9 bits (79), Expect = 0.32
Identities = 44/170 (25%), Positives = 73/170 (42%), Gaps = 21/170 (12%)
Query: 1612 KLENDKEYNITTKEK---TSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKP 1666
K EN+ E+ E+ T ++ L ++ IEA N AG ++S V+ K+ +
Sbjct: 14289 KRENEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVSKKLTVEG 14348
Query: 1667 SKPE---GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV---- 1719
PE +++ + + V + WK DG E + ++ ++ W V D+
Sbjct: 14349 LVPEIILDMPMVKVLDNDKVEVTWK---SDGEKE---FVVQYKSDGSSIWASV-DIGGPR 14401
Query: 1720 -DRDVETYCI-QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
+ + CI L E Y+FRV A+N G E E V+ A D P
Sbjct: 14402 SESAATSKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVVVLADDAP 14451
Score = 35.5 bits (78), Expect = 0.42
Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Query: 1091 LRDESCTAEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSE 1145
+RD+ + E+ LP P+I+ L + G + ++T A V W KD
Sbjct: 801 IRDDDSSFEIVPPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVN 860
Query: 1146 IQ---FSNHIQLTI-DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
++ + + T+ DG +L +C +DAG Y C N TA
Sbjct: 861 VEDWVLNKDVTTTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTA 906
Score = 35.5 bits (78), Expect = 0.42
Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 510 PIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P+ + KL +P G + ++ G P P++ + +++Y DN+A+L
Sbjct: 8856 PVILNKLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIY---DNIASL 8912
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEM 611
I ++ D G +T V +N G S + +V+ PL +++
Sbjct: 8913 YIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKPRKAQL 8956
Score = 35.5 bits (78), Expect = 0.42
Identities = 37/182 (20%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-----XYKC 1550
NE + + C P + W R+ +L Y Y C
Sbjct: 18121 NESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYAC 18180
Query: 1551 IAFNDHGEVETSC---VVGIQQKPVITISN----EDIKQKHKVGDEW---LVTAVIEGIP 1600
A N+ G T+ V G+ I E IK KV D L +++
Sbjct: 18181 EAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 18240
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
P ++ W +N + + ++ + E + I ++ +YT+EA N +G + + L
Sbjct: 18241 PLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQL 18300
Query: 1661 KV 1662
V
Sbjct: 18301 DV 18302
Score = 35.1 bits (77), Expect = 0.55
Identities = 22/96 (22%), Positives = 38/96 (39%), Gaps = 1/96 (1%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+S P F + + G+P P+I WF+ I + Q +
Sbjct: 15595 ESKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKR-QWIENIAGA 15653
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
+L I E+ +D G + V KN AG + +L ++
Sbjct: 15654 TSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMD 15689
Score = 34.7 bits (76), Expect = 0.73
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 5/91 (5%)
Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLEN 1364
TL D P P +W + K + S ++ A LT+K + +DAG Y R N
Sbjct: 16272 TLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATN 16331
Query: 1365 NCG----HADVEMNVTILDKPSPPGKPNILE 1391
+ G HA + + K P ++E
Sbjct: 16332 DLGSIMTHAKLSVKADEKKKKKSKTSPAVIE 16362
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PPK + + YR+ ++L+V+ + P EW N K + + + +++
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQV--GHGINIS 146
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
KV + G+YK N G
Sbjct: 147 RLKVSRPEQGVYKCVTRNPAG 167
Score = 33.9 bits (74), Expect = 1.3
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 633 PPTF-SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP F + P V+ ++L + AIP + AW G E+ +++ + D H
Sbjct: 405 PPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKKSQSV---VLLDEHNK 461
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGE-KEPPQVIEPLKSMIV 746
+++ VK +G Y V A N G S+ + ++K G EPP ++E ++
Sbjct: 462 STLVLHPPVK---QGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVTC 518
Query: 747 RQGESV 752
E V
Sbjct: 519 SHEEDV 524
Score = 33.9 bits (74), Expect = 1.3
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1017 PEFIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P+F+RKL + F + V + + ++ W DG+ I P ++Y + L
Sbjct: 1679 PKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPN-DEYSIVYEDGVCILR 1737
Query: 1076 IRNTSVHDEGEYSC 1089
I +T + DEGEY C
Sbjct: 1738 IESTLIEDEGEYCC 1751
Score = 33.1 bits (72), Expect = 2.2
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 11/135 (8%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
+ A + + P V W K+G + EN+K + + ++ I+ S YT A +
Sbjct: 964 MVATVRSVAPITVSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESE 1023
Query: 1651 AGTSS----VEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGLELTKYA-I 1703
G S+ VE+T+ P E I E+ + + + L + E++ A I
Sbjct: 1024 HGVSNSSCQVELTISAESSPESFEKVEITPPEEVKETGIDDDIEVILKE---EVSGTAQI 1080
Query: 1704 EKHEPDNNRWIKVAD 1718
EK E + +KVAD
Sbjct: 1081 EKREEEFKLLVKVAD 1095
Score = 33.1 bits (72), Expect = 2.2
Identities = 12/30 (40%), Positives = 20/30 (66%)
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
K G+ +T ++G P PE+IW KNG +++
Sbjct: 12296 KEGETAKLTGRVDGFPLPELIWIKNGKEID 12325
Score = 32.3 bits (70), Expect = 3.9
Identities = 42/190 (22%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 1345 LTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
LTI+ N D+G+Y E+ G ++ ++ +TI + SP + EI +
Sbjct: 1003 LTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELTISAESSPESFEKV-EITPP------E 1055
Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWIS-----VKNITKTQTSIQN-LKTNSSYRFRAYAV 1456
E + TG I +++ +E+ T I K + K + + L N AV
Sbjct: 1056 EVKETGIDDDIEVILK-EEVSGTAQIEKREEEFKLLVKVADQVASTLVANVFLEAVHEAV 1114
Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
++ ++ E + +E + ++ T E +K N I++ G P P + WY
Sbjct: 1115 KKIVETEDEEEDNQIEATQEPRFETSTDEYHVKE-----NGTIKMAATISGHPTPFLEWY 1169
Query: 1517 RDGKKLKTAK 1526
+KL+ ++
Sbjct: 1170 FGEEKLQVSQ 1179
Score = 32.3 bits (70), Expect = 3.9
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 9/101 (8%)
Query: 149 ERVTLEKSDLFDSQEDESKPDV-SQPPQNII--EEAKSEPKLIEESEQPIAKTSEIDNEV 205
E V E++ +QED K S+P Q + E A SEP ++ + A + I EV
Sbjct: 3565 EDVPKEEAPSEPTQEDVPKEAAPSEPTQENVPKEAAPSEPT--KDVPKEAAPSEPIQEEV 3622
Query: 206 PEKINVPDDKETSQTPTSFNKRSK-LTPIKIERKEMEVSTP 245
P++ + E +Q + +KRS+ + P +I++ E TP
Sbjct: 3623 PKEATL---SEPTQEQSEVSKRSEPVEPTQIQQAASEEETP 3660
Score = 31.5 bits (68), Expect = 6.8
Identities = 29/135 (21%), Positives = 52/135 (38%), Gaps = 6/135 (4%)
Query: 782 SDGDTHSIT--ILKPKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR 838
SDGDT + + PKK + DE V + + EN E ++ T + I
Sbjct: 8713 SDGDTQEVEQKVTLPKKHQSDEDVISKEEENLETSVSYGSIEETVSFTIGTGQS--IIEH 8770
Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
+ V + + ++ T P+ W+ N ++ P E + G L + +
Sbjct: 8771 PKSHAVGQMNSEVIIKCKTSQPISDAKWFCNGMVLLPDEQVNMTVTGCEAVLRLVKFLPQ 8830
Query: 899 IDSGDYKCVASNSAG 913
+ G+Y + S G
Sbjct: 8831 -NKGNYHVLIDGSIG 8844
Score = 31.5 bits (68), Expect = 6.8
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G TV+ G P+P++ W +I+ S+ ++ N L I + +D G F
Sbjct: 15709 GETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLN-TVLTINSIDSQDQGEFA 15767
Query: 583 CVAKNAAG 590
KN G
Sbjct: 15768 LKIKNRCG 15775
Score = 31.5 bits (68), Expect = 6.8
Identities = 20/87 (22%), Positives = 32/87 (36%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P P+V W K G LE +Y+I + + + Y A+N G +
Sbjct: 18017 ISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIIT 18076
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES 1682
+ V V R+ +E+
Sbjct: 18077 CTSEIDVLPNKEDSAAQVAKRKSRKEA 18103
Score = 31.1 bits (67), Expect = 9.0
Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS-QDFQMYYDDDNVAT 567
AP F+ ++ GS V + +V+ P + +WF + S +M+ D N +
Sbjct: 204 APRFLTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMFSPDVNRS- 262
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
V+R P AG + VA N G A S + ++ + S +T
Sbjct: 263 -VVRFSIPV-AGEYKVVASNVHGSAMSCGHVDIQKVIELEESTLT 305
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/81 (19%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
S +TL V + PQP W+++ +++ + ++ +++ V+ G K R
Sbjct: 3804 SKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCR 3863
Query: 1362 LENNCGHADVEMNVTILDKPS 1382
N G + + D+ S
Sbjct: 3864 ATNCAGQVETSCEIVAADEIS 3884
Score = 31.1 bits (67), Expect = 9.0
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 1014 ETIPEFIRKLQDFEVKEKD-VAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
+ P ++L+D D +A L +++ + V W +D + + KYD +
Sbjct: 16250 DAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGL 16309
Query: 1072 RKLYIRNTSVHDEGEYSC 1089
+L ++N D G+Y+C
Sbjct: 16310 AELTVKNIVESDAGKYTC 16327
>AY130758-1|AAN61517.1| 18534|Caenorhabditis elegans 2MDa_1 protein
protein.
Length = 18534
Score = 140 bits (340), Expect = 8e-33
Identities = 121/465 (26%), Positives = 198/465 (42%), Gaps = 30/465 (6%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
K ++ + P F+E L T +G+ + EC V G P P ITW++ + Y
Sbjct: 16695 KEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQY 16754
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAG--FASSTTELIVEAPLSDHGSEMTVXXXX 617
D V+ L I V D G +TC A N+ G F T + +V+ LS + +T
Sbjct: 16755 TDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK-VVDMGLSK--TRLTPVRSR 16811
Query: 618 XXXXXXXXADILEGI--PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675
+ + I PP ++ V EG+ LLE + P P I W G+ +
Sbjct: 16812 SRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVA 16871
Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---- 731
+ + + + LKI + G Y N+ G ++ ++ +
Sbjct: 16872 ESRTLRTYFDGRV----AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEH 16927
Query: 732 -KEPPQVIEPLKSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-- 787
+ P ++ L+ ++++ GE+ + Q NP + W N K ++ TKS+ T
Sbjct: 16928 VTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQ--QTKSNYKTRLF 16985
Query: 788 --SITILKPKKVKDE--GVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQ- 840
+ L + V DE G YT A N G TSA +T+ E + A P FI +
Sbjct: 16986 DDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKP 17045
Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
+I V E T+ + A + +P+P + W ++N + S+ I DG N +L++ +V E D
Sbjct: 17046 KINVVEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLE-D 17104
Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGK 944
G Y A N GK V++ K V K +K + +EGK
Sbjct: 17105 EGTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGK 17149
Score = 138 bits (335), Expect = 3e-32
Identities = 109/480 (22%), Positives = 205/480 (42%), Gaps = 17/480 (3%)
Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNK 1062
+ T ++V+ + P ++ ++ ++ +K LE A + +W +DG+ I P
Sbjct: 14438 EPTIPVVVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDEN 14497
Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELPPEIITRLQN-QK 1117
+ G + L I + D G Y ++ + TAE V + ++ + +
Sbjct: 14498 TEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELTE 14557
Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
+ +G+ E++ +A+V W+KDG ++ S+ +Q +K+ L+I D+G Y
Sbjct: 14558 IEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADSGVYK 14617
Query: 1178 CEV--GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235
CE G S+ + V E + + + I+ L E V W+K
Sbjct: 14618 CETTDGRSRTEGEVIVNEQEPHILVGPQDAIVKDFGETMVLFCETSKPVRKVKWFKNGVE 14677
Query: 1236 I-EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV--- 1291
I K + +D K+ TL I+ + D YT + + +++ K+ V E P ++
Sbjct: 14678 IWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEKETSAPAKL-VFEVAPNLIIPT 14736
Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
+ + G++ V++ FP P N +K DS S+ +K V
Sbjct: 14737 EIRDGVTVHAGNEFDFAVEFSGFPIPTIHLTNNGTPLKAIAVVTEYDDS--VSVRMKDVT 14794
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
++G ++ E+ G E+ + I+DKPS P E+ S+ + W P T +
Sbjct: 14795 LDNSGTVRVIAESPLGQCIKEIPLKIIDKPSAPCDLQFKEVTEDSVFLSWQPPLETNGAP 14854
Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTE 1469
+ YV+E + +D W + T+ + ++L N Y FR AVNEV S+ +T +
Sbjct: 14855 LTGYVIERKAVDNNRWRPCGQVKPTKLTFVAEDLFCNQVYGFRILAVNEVGESEPCDTVD 14914
Score = 138 bits (334), Expect = 4e-32
Identities = 226/1028 (21%), Positives = 398/1028 (38%), Gaps = 137/1028 (13%)
Query: 473 YLMDENNYTQYLQKKLNE----KIDKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPD-GST 526
Y E + QY+ K N+ + + V E P + E + P FV+KL+ G T
Sbjct: 16890 YEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGET 16949
Query: 527 VQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
F CQ P Q+ W A+ + +++ DDN ATLVI V E GT+T VA
Sbjct: 16950 ATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVA 17009
Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
N G ++ +L + GSE I+E KPK V
Sbjct: 17010 NNQFGDVHTSAQLTIS------GSEAKKIAASLPYF------IIE-------LKPKINVV 17050
Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
EG+ + ++ L P P++ WL E+V + I + + + L + +V E
Sbjct: 17051 -EGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQ----LLVRDVGLEDE 17105
Query: 706 GTYTVVAVNREGE----ASLPIVLKIKTGEKEPPQVIE--------PLKSMIVRQGESVI 753
GTYT+ A N +G+ + + + EK+ + +E P + + R +
Sbjct: 17106 GTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASK 17165
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITI-LKPKKVKDEGVYTLKAE 808
+ P+ + + + P + + G T S+ + +K E ++ + +
Sbjct: 17166 TEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGK 17225
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
N +G+ E S + + + P I+ +I ++ + P PS+ WY+
Sbjct: 17226 NKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK 17285
Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
N I P E I + I N+ S+ ++G + C+ N G++S +VTI +
Sbjct: 17286 ENLQIVPDEKIDVATTSTSS---ILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPA 17342
Query: 929 TF------------VKHLQKSYETEE---GKTVILECQ-TSHTVST-KWYHNKKEISGMD 971
+ V LQK+ E G+ ++L C+ +S + ST W+ + + I
Sbjct: 17343 SLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAG 17402
Query: 972 HREIIQEGRXXXXXX-XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI----PEFIRK 1022
E+ + + D G +C+V ++ E+ + V++ P F
Sbjct: 17403 RYELSSDKKSNHKLVCHAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSAT 17462
Query: 1023 LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
L D LE ++ A +V W +DGE I + + KL I
Sbjct: 17463 LSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAES 17522
Query: 1082 HDEGEYSC----ILRDESCTAEVTVVELPPE----IITRLQNQK---------------V 1118
D G Y C + +S ++ V + + +I + ++K V
Sbjct: 17523 DDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEV 17582
Query: 1119 NKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDD-AGE 1175
N+ + T + + V W KDG EI +N I + G + I +C + +G
Sbjct: 17583 NESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGI 17642
Query: 1176 YSCEVGNSKCTAILTVE------EPSIN-------FTLRLPEFILV---PANTDAYLTVE 1219
+SC+ N T I + +P+ FT+ L + +V P +T
Sbjct: 17643 FSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGS 17702
Query: 1220 IPDETLDVTWYK----KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA-- 1273
P+ TL+ + K ++ T +T K L + + + Y C+ ++
Sbjct: 17703 -PEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSG 17761
Query: 1274 KSTTKLKVEVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
++TT+ + V E PP+ V ++ + V+ FP P+ W N K
Sbjct: 17762 QATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKK 17821
Query: 1328 IKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD---KPSP 1383
I + K K + S + S L+IK V G+Y + N G + + D K P
Sbjct: 17822 INEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDERRKAEP 17881
Query: 1384 PGKPNILE 1391
P ++LE
Sbjct: 17882 PQFKHVLE 17889
Score = 135 bits (326), Expect = 4e-31
Identities = 139/503 (27%), Positives = 207/503 (41%), Gaps = 46/503 (9%)
Query: 435 EAINLVEGERLYILDTSNQDWWYVQKH--LTEEKGWVPAQYLMDENNYTQYLQ-KKLNEK 491
E I L G + I + D++Y++ H T +KG+ +E T + L K
Sbjct: 18045 EGIILETGNKYSIYNDG--DFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNK 18102
Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAII 550
D K S +++ AP F+E L + + ++ EC V YP I W R + +
Sbjct: 18103 EDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRL 18162
Query: 551 KPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
P D + M YD + A+L V P D GT+ C A N G A + L V
Sbjct: 18163 LPQADRYTMSYDGE-CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSG------- 18214
Query: 610 EMTVXXXXXXXXXXXXADILEGIPPTF--SKKPKAQYVDEGSDILLECRLVAIPEP-DIA 666
+ EGIPP F K + V +GS + L LV EP I
Sbjct: 18215 --------------VDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIR 18260
Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
WL IV + S + +M L I +V G YTV A N+ G A + L
Sbjct: 18261 WLRNKVTIVDSPSFSYSRSENMVF----LTIADVFPEDGGEYTVEAKNQSGIARCTMQLD 18316
Query: 727 IKTGEK----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALP 779
++ E+ E P+V + + G SV L A+V+G+P P I+W K + + +
Sbjct: 18317 VRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYM 18376
Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
+++GD + I + D G Y L A N G A +TV + T+ P F
Sbjct: 18377 MRNEGDKFILRIANVTRA-DAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESP 18435
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSE 898
+ EK +L A + P P+ W Y NE+I + T N L+I +VD +
Sbjct: 18436 ISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKK 18495
Query: 899 IDSGDYKCVASNSAGKSSHGARV 921
G+Y C N G+ A +
Sbjct: 18496 -HFGEYLCTIRNQNGEELANAMI 18517
Score = 133 bits (321), Expect = 2e-30
Identities = 100/386 (25%), Positives = 169/386 (43%), Gaps = 17/386 (4%)
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISV-KNITKTQTSIQN 1442
GKP + ++SI + W T ++ + Y V+ +E ++ W V K I++ +I
Sbjct: 15505 GKPEYVSSTATSIALKW-----TSDNDEVTYTVQMKEANSKRPWAVVAKEISECSATIAQ 15559
Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
LK +SY FR A N+ + SE +E + T+ + P ++T N ++T
Sbjct: 15560 LKEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTESKKPAFTNAPTDLTAVKNGKTKIT 15619
Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATY-EN---RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
F G P P++ W+++ K++ + K + EN YK + N G
Sbjct: 15620 AEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMREDDEGEYKIVVKNTAGS 15679
Query: 1559 VETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY-KNGNKLEND 1616
VE SC + + Q P I + G+ + G P PEVIW NG +E
Sbjct: 15680 VEHSCKLTMDQLPEINRVDRYASTLVFDKGETVKLRLSFSGRPQPEVIWIDNNGKVIEES 15739
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
++ I +V+ I + ++ ++ N G + ++V D+P+ P P +
Sbjct: 15740 RKMKIEKTVLNTVLTINSIDSQDQGEFALKIKNRCGEDKYAIGIQVTDRPAAPGKPAV-E 15798
Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
+ + +SV + W P +DGG + Y +E W K A+V + + L
Sbjct: 15799 DQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWTK-AEVTKQA-FITLFNLVPGES 15856
Query: 1737 YMFRVIAQNPVGFSE-ALESEPIVIK 1761
Y FRV A N G SE + ESE +V+K
Sbjct: 15857 YRFRVRADNTFGQSEPSDESELVVVK 15882
Score = 129 bits (312), Expect = 2e-29
Identities = 133/630 (21%), Positives = 248/630 (39%), Gaps = 73/630 (11%)
Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
++ PP + L + V +GN+ E+E+ + W+ DG + S ++ DG+
Sbjct: 16826 IQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVA 16885
Query: 1162 KLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSI--------NFTLRLPEFILVP 1209
LKIY+ + G+Y C+V N + AI+ VE P F +L + +L
Sbjct: 16886 FLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 16945
Query: 1210 ANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKF--TLISDVKKRTLIIRKCTEDDQCEY 1266
A A T + + V W ++ T+ T + D TL+I T++ Y
Sbjct: 16946 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 17005
Query: 1267 TCVLL----DAKSTTKLKVEVVE-------FPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
T V D ++ +L + E P I++ + + + G+ +++ D P
Sbjct: 17006 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 17065
Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEM 1373
P W+ ++ + + + D + L ++ V D G Y + EN G + E+
Sbjct: 17066 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 17125
Query: 1374 NVT----ILDK------------PSPPGKPNILEIDSSS----INICWDEP-ENTGNSTI 1412
+VT + +K PG+P + +S + + +D P E +S
Sbjct: 17126 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADS-- 17183
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
Y VE + D EW+S + + I+ L N+ Y FR N+ + + SE T K
Sbjct: 17184 --YEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLK 17241
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYE 1530
+ T+ P I +++ E+ F G P P V WY++ ++ +
Sbjct: 17242 TASVGQAPQFTI-SPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVAT 17300
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---------------VITI 1575
+ C+ N+ G+ SC V I KP V T+
Sbjct: 17301 TSTSSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTL 17360
Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634
+ + G + ++T I V W+K+ ++E+ Y +++ +K++ +
Sbjct: 17361 QKALNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHA 17420
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
++ + KY +N G + E + V D
Sbjct: 17421 VQSQDTGKYRCVVTNKYGYAESECNVAVED 17450
Score = 128 bits (310), Expect = 3e-29
Identities = 180/773 (23%), Positives = 292/773 (37%), Gaps = 104/773 (13%)
Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543
++KK + K K+ V E E M P F L+ G P P + W
Sbjct: 16376 IEKKKDRKTSKVVVIE----EMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDW 16431
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ I + + D L I V D G + V KNA G S +L V P
Sbjct: 16432 YHNGEHISINDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIP 16491
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP 663
+ P+F K+ E + LE + A P P
Sbjct: 16492 DGQYA-------------------------PSFGKQLSDVKCSESDILKLEVNIQANPAP 16526
Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+I W EI ++ + + Y L I + G Y VA N+ G+A
Sbjct: 16527 EINWFRNESEIEHSQHHRLQFDDGSGNYS--LTIIDAYAEDSGEYKCVAKNKIGKAHTVC 16584
Query: 724 VLKIKT----------GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
++I+ G K P ++ V QG + L V G P P I W K++K
Sbjct: 16585 CVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDK 16644
Query: 774 PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
P+ + + T+ + + D+G Y +AEN G+A++ +V+ ++E +++
Sbjct: 16645 PIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVR 16704
Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE-----N 887
P F+ + E + L VT P+P+ITWY++ + + Q D + N
Sbjct: 16705 PKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLN 16764
Query: 888 IELVITNVDSE--------------------IDSGDYKC----VASNSAGKSSHGARVTI 923
I V+ N D E +D G K V S S +S + V
Sbjct: 16765 IMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGG 16824
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRX 981
++++ V EG +LE + T + +WYH+ K ++ +GR
Sbjct: 16825 EIQRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRV 16884
Query: 982 XXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET--------IPEFIRKLQDFEVK 1029
G C V ++ ET ++VV+ +P F++KLQD +K
Sbjct: 16885 AFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK 16944
Query: 1030 EK-DVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEK-RGHIRKLYIRNTSVHDEGE 1086
+ A + + A VVW +G+ ++ K+ Y + L I N + G
Sbjct: 16945 TAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 17004
Query: 1087 YSCILR----DESCTAEVTV--------VELPPEIITRLQNQKVNKGNKATFEIELT-KG 1133
Y+ + D +A++T+ P I L+ K+N AT I+ G
Sbjct: 17005 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELK-PKINVVEGATLSIQADLNG 17063
Query: 1134 DAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
+ V W KD SE+ S+ IQ+ DG +L + D L+D G Y+ N K
Sbjct: 17064 SPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEK 17116
Score = 123 bits (297), Expect = 1e-27
Identities = 121/517 (23%), Positives = 219/517 (42%), Gaps = 39/517 (7%)
Query: 510 PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F+ K +P+ + +++ + + G P PQ+ W ++ I++ + +Y D D L
Sbjct: 18008 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGD-FYYL 18066
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
+ V D G + C A N G + T+E+ V D +++ ++
Sbjct: 18067 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 18126
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESD 687
L G ++Q + + +EC + A P I W ++P + +++ + +
Sbjct: 18127 LPG---------RSQ-ANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGE 18176
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL----KS 743
C+ LK +V EGTY AVN G A + L++ + + I PL K
Sbjct: 18177 ----CASLKFISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKI 18232
Query: 744 MIVRQ---GESVILSAQVVGNPRP-TITWCKNNKPVKALPTKSDGDTHSITILKPKKV-- 797
VR+ G V L+A++V P I W +N + P+ S + ++ L V
Sbjct: 18233 KSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFP 18292
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARV 856
+D G YT++A+N GIA + + V A+ + F+ T + G +++L A+V
Sbjct: 18293 EDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKV 18352
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
+P P I+W + + ++ E +G+ L I NV + D+G Y+ A N +G+++
Sbjct: 18353 IGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANV-TRADAGKYELTAINPSGQAN 18411
Query: 917 HGARVTIDVEKVTFVKHLQK------SYETEEGKTVILECQTSHT--VSTKWYHNKKE-I 967
+T+ V+ V K S +T E L S T + +W++N E I
Sbjct: 18412 AELELTV-VQSTKTVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI 18470
Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
G+D I G C +++Q
Sbjct: 18471 DGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTIRNQ 18507
Score = 118 bits (283), Expect = 6e-26
Identities = 156/683 (22%), Positives = 273/683 (39%), Gaps = 55/683 (8%)
Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSID 1339
V + + P+++ + +I + ++ L P P W + K II ++T+ +
Sbjct: 14444 VVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNE 14503
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEIDSS-S 1396
++L I ++ D G+YK+ +EN G A+ E V I D + + EI+
Sbjct: 14504 GSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELTEIEEGHD 14563
Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
I + E + ++ + + +++ ++ + + + +T T++ V
Sbjct: 14564 IELTC---EVSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADS-----GV 14615
Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
+ + +D TE ++ E Q P + P I + E + L C P KV W
Sbjct: 14616 YKCETTDGRSRTEGEVIVNE---QEPHILVGPQDAIVKDFGETMVLFCETSK-PVRKVKW 14671
Query: 1516 YRDGKKL--KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+++G ++ + KA EN R Y V +
Sbjct: 14672 FKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEKETSAPAKLVFEVAPN 14731
Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV- 1629
+I D H G+E+ G P P + NG L K + T+ SV
Sbjct: 14732 LIIPTEIRDGVTVH-AGNEFDFAVEFSGFPIPTIHLTNNGTPL---KAIAVVTEYDDSVS 14787
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689
+R+K++ +S + A + G E+ LK+ DKPS P + +E++ +SV + W+P
Sbjct: 14788 VRMKDVTLDNSGTVRVIAESPLGQCIKEIPLKIIDKPSAP-CDLQFKEVTEDSVFLSWQP 14846
Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
PL+ G LT Y IE+ DNNRW V T+ + L N Y FR++A N VG
Sbjct: 14847 PLETNGAPLTGYVIERKAVDNNRWRPCGQVKPTKLTFVAEDLFCNQVYGFRILAVNEVGE 14906
Query: 1750 SEALE---------SEPIVIKTALDVPSXXXXXX--XXXXIDNESVYITWFPSEKNGGSP 1798
SE + SEP+ + L VP +D V + W E+ +
Sbjct: 14907 SEPCDTVDVLTLESSEPVSESSELFVPKIAILRTPQVTVAVDETKVTLRW---EECPETS 14963
Query: 1799 IIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP--YTSDD 1855
+ YKVE K+ G W + + L+ + Y +++ A S P T+
Sbjct: 14964 L--YKVERKKVGDSDWLEIANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPV 15021
Query: 1856 KITIGKTLTPPSQPR---NFVVSESTSRSV--TLKWTEPESNGGSPITNYIIEFKTVKGK 1910
KI + + P S+ + SES +S + + + + S T +E K K
Sbjct: 15022 KILVPGSEMPASKTEKKTDAAKSESEQKSAEEIVAEKQVDQSQASESTTEAVEEKKTKKV 15081
Query: 1911 SWTKIVTVGGSVHEHCIENIKEK 1933
K+ G E ++ +KEK
Sbjct: 15082 VKKKVAENKG---EETLQEVKEK 15101
Score = 116 bits (280), Expect = 1e-25
Identities = 109/451 (24%), Positives = 187/451 (41%), Gaps = 29/451 (6%)
Query: 1512 KVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
KV W +DGK L+ K T YK + V+ S + I
Sbjct: 13996 KVVWLKDGKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDG----VDCSTHLSI 14051
Query: 1568 QQKPVI-TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
Q KPV+ +S D++ + + P +G LE D I +
Sbjct: 14052 QGKPVLKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDD 14111
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
+ + + ++ + +Y ++ N G + + +KV D PS P G V + + + + IE
Sbjct: 14112 GLKLTKRGVSKTDAGEYEVKLKNEFGEVAQKFDVKVNDTPSAP-GDVSVVKAESDCLHIE 14170
Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
W P +D G E+T Y IEK E ++ KVA V+ +Y + L Y+ R+ A N
Sbjct: 14171 WTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNK 14230
Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV-- 1804
G E +E++P+ + VP+ + + S ++W ++GGSP+ Y V
Sbjct: 14231 FGTGEFIETKPVQTGSPFQVPT-VEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDVYK 14289
Query: 1805 -EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKT 1862
E + E +K ++ LS Y+F+I A NE G S K+T+ +
Sbjct: 14290 RENEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVSKKLTV-EG 14348
Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
L P +V + V + W +S+G +++++K+ W V +GG
Sbjct: 14349 LVPEIILDMPMVKVLDNDKVEVTW---KSDGEK---EFVVQYKSDGSSIWAS-VDIGGPR 14401
Query: 1923 HEHC------IENIKEKDEIIFRISAENTVG 1947
E I+ ++E +FR++A N G
Sbjct: 14402 SESAATSKCIIDGLREGIPYVFRVAARNQHG 14432
Score = 113 bits (273), Expect = 1e-24
Identities = 88/381 (23%), Positives = 168/381 (44%), Gaps = 10/381 (2%)
Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG-EYSC 1178
+G+ E EL D V W +G + ++ + L I + + D+G E +
Sbjct: 13887 RGDNVEIEAELLAEDDTVTWKVNGKDADLNSRCHEMSHTFFRTLIIDEVEPTDSGMEITA 13946
Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI--PDETLDVTWYKKKSVI 1236
G T IL VEE ++F LP + ++V + P + V W K +
Sbjct: 13947 TCGTESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPL 14006
Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
E + +++ + +L +R+ +D +Y V +T L ++ + + +
Sbjct: 14007 EINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKPVLKNVSETKPV 14066
Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
+ + +LLV Y + P+ + V+ K ++ ++ + LT + V TDAG
Sbjct: 14067 ITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLTKRGVSKTDAG 14126
Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
Y+++L+N G + +V + D PS PG ++++ +S ++I W P + + YV
Sbjct: 14127 EYEVKLKNEFGEVAQKFDVKVNDTPSAPGDVSVVKAESDCLHIEWTAPTEDNGAEVTSYV 14186
Query: 1417 VEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
+E +E ++ V + +TS + +L+ + Y R AVN+ + ET V
Sbjct: 14187 IEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGTGEFIETK---PVQ 14243
Query: 1475 KETKIQSPTVEKP--LKNITT 1493
+ Q PTVE P + N+T+
Sbjct: 14244 TGSPFQVPTVEFPPTIDNVTS 14264
Score = 110 bits (264), Expect = 1e-23
Identities = 101/400 (25%), Positives = 169/400 (42%), Gaps = 28/400 (7%)
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDT--HSITILKPKK--------VKD---EG-- 801
+V+ N + +TW + + + KSDG + S+ I P+ + D EG
Sbjct: 14361 KVLDNDKVEVTWKSDGEKEFVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIP 14420
Query: 802 -VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
V+ + A N G E S ++A P + + + + +KG ++L +P
Sbjct: 14421 YVFRVAARNQHGTGEFSEPTIPVVVLADDA--PRVLKAIKPVKIPKKGELRLECHAAGHP 14478
Query: 861 VPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P WY++ + I P++ T+ +G L+I + E D G YK + N G + A
Sbjct: 14479 APEYIWYKDGKEIIPTDENTEIVNEGSMSALIIHELAGE-DVGLYKVLVENIHGTAESEA 14537
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE 978
V I + F + E EEG + L C+ S WY + K++ D +
Sbjct: 14538 EVGISDVRAHFNSSFSELTEIEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRVQFYAM 14597
Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD--QETSTMLVVKETIPEFIRKLQDFEVKE-KDVAI 1035
R D GV KC D T ++V E P + QD VK+ + +
Sbjct: 14598 ARKRTLRIKGSTDADSGVYKCETTDGRSRTEGEVIVNEQEPHILVGPQDAIVKDFGETMV 14657
Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
L E + V W ++G I P+ NK E G L I+N HD G Y+ + ++
Sbjct: 14658 LFCETSKPVRKVKWFKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEKE 14717
Query: 1096 CTAEVTVV-ELPPEII--TRLQN-QKVNKGNKATFEIELT 1131
+A +V E+ P +I T +++ V+ GN+ F +E +
Sbjct: 14718 TSAPAKLVFEVAPNLIIPTEIRDGVTVHAGNEFDFAVEFS 14757
Score = 110 bits (264), Expect = 1e-23
Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 12/318 (3%)
Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDV 1248
T E FT P + N +T E ++ W+K K I ++ + +
Sbjct: 15593 TTESKKPAFT-NAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIA 15651
Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPP--KIVDYEREYRIKRGSD 1304
+L I + EDD+ EY V+ + + + K+ + + P ++ Y +G
Sbjct: 15652 GATSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQLPEINRVDRYASTLVFDKGET 15711
Query: 1305 VTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
V L + + PQP WI N+ K+I++ + K + LTI +++ D G + L+++
Sbjct: 15712 VKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFALKIK 15771
Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
N CG + + + D+P+ PGKP + + + S+ + W P N G S + Y VE
Sbjct: 15772 NRCGEDKYAIGIQVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEK 15831
Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
W + + ++ NL SYRFR A N S+ S+ +E V+K S
Sbjct: 15832 GKTWTKAEVTKQAFITLFNLVPGESYRFRVRADNTFGQSEPSDESELV-VVKNV---SRV 15887
Query: 1484 VEKP-LKNITTEPNEDIE 1500
VE+P K + + E ++
Sbjct: 15888 VEEPKKKEVKVKEQESVD 15905
Score = 108 bits (259), Expect = 5e-23
Identities = 114/496 (22%), Positives = 201/496 (40%), Gaps = 42/496 (8%)
Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ-FECQVEGYPRPQITWFRQTA-IIKPSQ 554
VFE+ + + AP ++L G + C V+G P P++ W++ + PS
Sbjct: 16255 VFERNIAFDTDAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSM 16314
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614
+ +Y++ +A L ++ + DAG +TC A N G + +L V+A T
Sbjct: 16315 KYDSFYNE-GLAELTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSP 16373
Query: 615 XXXXXXXXXXXADI-----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
+ + + +PP F + G +L +PEP + W
Sbjct: 16374 AVIEKKKDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYH 16433
Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
GE I +++ + + D Y L I +V EG + V N GE L +
Sbjct: 16434 NGEHISINDS-NYLRKHDKGRY--ELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVI 16490
Query: 730 GEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSD 783
+ + P + L + + + + L + NP P I W +N ++ L
Sbjct: 16491 PDGQYAPSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDG 16550
Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE------ENAEPPLFIN 837
+S+TI+ +D G Y A+N G A T + +EE + ++ P F
Sbjct: 16551 SGNYSLTII-DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRF-- 16607
Query: 838 RFQEITVKE--KGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
R Q T +E +G + LV V+ P P+I W ++++ I S ++ +G +I
Sbjct: 16608 RMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGA 16667
Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-------ETEEGKTVI 947
D D G Y C A N G + + +++++ H++ + T EG ++
Sbjct: 16668 RDD--DQGRYVCEAENIHGVAQSFS--VVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMV 16723
Query: 948 LE-CQTSHTVST-KWY 961
LE C T + T WY
Sbjct: 16724 LECCVTGKPIPTITWY 16739
Score = 108 bits (259), Expect = 5e-23
Identities = 124/516 (24%), Positives = 206/516 (39%), Gaps = 72/516 (13%)
Query: 638 KKPKAQYVDEGSDIL--LECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSV 694
KK V D++ L C + +P P + W +E+ VP S+ +S + +
Sbjct: 16271 KKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVP----SMKYDSFYNEGLAE 16326
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE------KEPPQVIEPLKS----- 743
L + N+ + G YT A N G L +K E K P VIE K
Sbjct: 16327 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSK 16386
Query: 744 -MIVRQ-------------------GESVILSAQVVGNPRPTITWCKNNKPVKALPT--- 780
+++ + GE IL P PT+ W N + + +
Sbjct: 16387 VVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYL 16446
Query: 781 -KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
K D + + IL DEG + +N+ G E+ A +TV P + A P F +
Sbjct: 16447 RKHDKGRYELHILSVDST-DEGKWKAVGKNAFGECESEAKLTVVIPDGQYA--PSFGKQL 16503
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ E +KL + NP P I W+RN I S+ FD + +T +D+
Sbjct: 16504 SDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYA 16563
Query: 900 -DSGDYKCVASNSAGKSSHGARVTIDV------EKVT------FVKHLQKSYETEEGKTV 946
DSG+YKCVA N GK+ V I+ +K+ F L E +G +
Sbjct: 16564 EDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADL 16623
Query: 947 ILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD- 1003
L C S T + KW + K I M ++++ E D G C ++
Sbjct: 16624 TLVCSVSGTPHPNIKWTKDDKPID-MSNKQVRHENGVCTLHIIGARDDDQGRYVCEAENI 16682
Query: 1004 ---QETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
++ +++ +KE + P+F+ L + E + +LE + + + W +DG
Sbjct: 16683 HGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDG 16742
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
+ + + R + +L I N ++D+GEY+C
Sbjct: 16743 LKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTC 16778
Score = 97.9 bits (233), Expect = 7e-20
Identities = 124/553 (22%), Positives = 215/553 (38%), Gaps = 45/553 (8%)
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQSPTVEKPL--KN 1490
T + S L+ NS + + +++ +D +ET E + KET + V K + K
Sbjct: 15132 TSEKRSEAELEKNSEKSAEKKSTSADLEAADKAET-EKSETGKETTEKKKKVVKKVAKKG 15190
Query: 1491 ITTEPNEDIELTC-----IFGGVPQPKVT--WYRDGKKLKTAKATYENRXXXXXXX--XX 1541
+ IELT I V + V+ W +DGK L +
Sbjct: 15191 LVKADKSKIELTAGKEGEISAQVAETGVSVEWKKDGKALDASYTVTSTGGVSTVKIPIVD 15250
Query: 1542 XXXXXXYKCIAFNDHG-EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
+ C + G E E S V ++ V + E + KVGD ++A I P
Sbjct: 15251 VNTSGVFTCKVKSSEGDEEEVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISE-P 15309
Query: 1601 PPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
V W K+ ++ D + + T+ + I + +HS Y + N AG VE+
Sbjct: 15310 ASSVNWTKDDKPIKEDGNVKAQLSPDGTAQLTISKTDSAHSGIYKLNVENDAGKGKVEIA 15369
Query: 1660 LKVYDK----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
L++ P P GP++ +++ S WK P ++GG E+T Y +E+ E N W K
Sbjct: 15370 LRIKGAAKGAPGIPTGPIVFDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGW-K 15428
Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
++++ + L E +Y +V A N +G ALE + +K +
Sbjct: 15429 QCGKTKELK-FKADGLEEGTDYDVKVSAVNTMGTGSALEGKITTLKKKEETGKQKSEKSE 15487
Query: 1776 XXXIDNES------------VYI----TWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXX 1817
+ES Y+ T + + + Y V++K+ K W
Sbjct: 15488 SDEKKSESDKVSELKQIGKPEYVSSTATSIALKWTSDNDEVTYTVQMKEANSKRPWAVVA 15547
Query: 1818 XXXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP--RNFVV 1874
A I +L T+Y FR+ A+N+ G ++ + I K T +P N
Sbjct: 15548 KEISECSATIAQLKEGTSYLFRVIAQNKTGQTVTSEQSESIEC-KDTTESKKPAFTNAPT 15606
Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
+ ++ K T + +P ++ K + I + G+ I ++E D
Sbjct: 15607 DLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGAT-SLTIGEMREDD 15665
Query: 1935 EIIFRISAENTVG 1947
E ++I +NT G
Sbjct: 15666 EGEYKIVVKNTAG 15678
Score = 93.9 bits (223), Expect = 1e-18
Identities = 155/717 (21%), Positives = 281/717 (39%), Gaps = 84/717 (11%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN-KYDFEKRGHIRKL 1074
P R L D V E + +LEVE++ T + W DG+++ + + F+ R K+
Sbjct: 16830 PVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKI 16889
Query: 1075 YIRNTSVHDE--GEYSCILRDESCTAE---VTVVELP---------PEIITRLQNQKVNK 1120
Y H+E G+Y C + ++ E + VVE P P + +LQ+ +
Sbjct: 16890 Y----EAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 16945
Query: 1121 -GNKATFEIELTKGDAL-VRWFKDGSEIQF--SNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
G ATF + A V W +G +Q SN+ D L I + + G Y
Sbjct: 16946 AGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGTY 17005
Query: 1177 SC----EVGNSKCTAILTVE-EPSINFTLRLPEFIL-----VPANTDAYLTVEIP---DE 1223
+ + G+ +A LT+ + LP FI+ + A L+++
Sbjct: 17006 TAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGSP 17065
Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+V W K S + ++++ + D L++R +D+ YT + K + EV
Sbjct: 17066 IPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNTEV 17125
Query: 1284 VEFPPKIVDYEREYR----------------IKRGSDVTLLVDY-QAFPQPNDEWIVNSK 1326
K V ++E + + R S + AF P++ + +
Sbjct: 17126 SVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQVTMAFDAPSEGPADSYE 17185
Query: 1327 IIKKCKHTKPSID---SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
+ ++C + + +KS L IK + I+++ +N G + + L S
Sbjct: 17186 VERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLKTASV 17245
Query: 1384 PGKPNILEIDSSSINICWDEP-----ENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQ 1437
P S I D+ E +G T + + E +I E I V T +
Sbjct: 17246 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVA--TTST 17303
Query: 1438 TSIQNLKTNSSY-RFRAYAVNEVDISDAS-ETTEYYKV--IKETKIQS------PTVEKP 1487
+SI NLK+ F NE+ + AS + T + K ++ T S PT++K
Sbjct: 17304 SSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKA 17363
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXX 1542
L N + + + I LTC + V W++D +++++A + ++
Sbjct: 17364 LNNESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQS 17423
Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ--KPVITISNEDIKQKHKV-GDEWLVTAVIEGI 1599
Y+C+ N +G E+ C V ++ K + + + + G + +EG
Sbjct: 17424 QDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGS 17483
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS 1655
P PEV W K+G ++ + T E + + I + + Y A++ AG S
Sbjct: 17484 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDS 17540
Score = 93.1 bits (221), Expect = 2e-18
Identities = 58/185 (31%), Positives = 95/185 (51%), Gaps = 3/185 (1%)
Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
PS P + V ++ S + ++WT P + G+ +T+Y+IE K + + K+ TV G +
Sbjct: 14151 PSAPGDVSVVKAESDCLHIEWTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSY 14210
Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
+++++ + I RI+A N G E++ V+ VP+ P I V S
Sbjct: 14211 VVDDLEIETPYIVRIAAVNKFGTGEFIETKPVQTGSPFQVPTVEFPP-TIDNVTSTSCSL 14269
Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
SW P DGG+P+ GY++ R+ + W ++ G+ V T FN+R LS Y +I A
Sbjct: 14270 SWPKPIEDGGSPVYGYDVYKRE-NEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEAC 14328
Query: 2045 NEIGL 2049
NE GL
Sbjct: 14329 NEAGL 14333
Score = 92.7 bits (220), Expect = 3e-18
Identities = 139/664 (20%), Positives = 250/664 (37%), Gaps = 48/664 (7%)
Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG-EYSCILRDE 1094
+E E+ +E V W+ +G+ ++ R L I D G E + E
Sbjct: 13893 IEAELLAEDDTVTWKVNGKDADLNSRCHEMSHT-FFRTLIIDEVEPTDSGMEITATCGTE 13951
Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNK-GNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151
S T + V ELP + + L + K G + T + L + V W KDG ++ +
Sbjct: 13952 SHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPLEINKD 14011
Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEFILVPA 1210
+ G L + +D+G+Y C+ L+++ +P + I V
Sbjct: 14012 YSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKPVLKNVSETKPVITVDK 14071
Query: 1211 NTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
+ L V P+ + +T K + + ++ D K T R ++ D EY
Sbjct: 14072 DDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLTK--RGVSKTDAGEYE 14129
Query: 1268 CVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
L + + K V+V + P D +K SD L +++ A + N + +
Sbjct: 14130 VKLKNEFGEVAQKFDVKVNDTPSAPGDVSV---VKAESDC-LHIEWTAPTEDNGAEVTSY 14185
Query: 1326 KIIKKCK-----HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI--- 1377
I KK H +++ K S + +E I ++ N G + +
Sbjct: 14186 VIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGTGEFIETKPVQTG 14245
Query: 1378 --LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNI 1433
P+ P I + S+S ++ W +P G S + Y V Y+ + EW ++ + +
Sbjct: 14246 SPFQVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDV-YKRENEGEWQKMNGEEL 14304
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
T++ +++ L + Y F+ A NE + S K+ E + ++ P+ +
Sbjct: 14305 VFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVS-KKLTVEGLVPEIILDMPMVKVL 14363
Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX------XXXXXXX 1546
N+ +E+T G + V + DG + + R
Sbjct: 14364 --DNDKVEVTWKSDGEKEFVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIPY 14421
Query: 1547 XYKCIAFNDHGEVETS-----CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
++ A N HG E S VV P + + + +K K E + G P
Sbjct: 14422 VFRVAARNQHGTGEFSEPTIPVVVLADDAPRVLKAIKPVKIPKK--GELRLECHAAGHPA 14479
Query: 1602 PEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
PE IWYK+G + + D+ I + S + I EL Y + N GT+ E +
Sbjct: 14480 PEYIWYKDGKEIIPTDENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEV 14539
Query: 1661 KVYD 1664
+ D
Sbjct: 14540 GISD 14543
Score = 89.8 bits (213), Expect = 2e-17
Identities = 99/445 (22%), Positives = 176/445 (39%), Gaps = 37/445 (8%)
Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQ 557
P + + AP VE L DG + C++ P + W + ++ ++D
Sbjct: 812 PPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVT 871
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXX 615
D V L+ E F EDAG + C A N G A + + VE + DH E +
Sbjct: 872 TTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDH-EEAEISE 930
Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQ--YVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
D+ +PP F + A+ + + + + ++ ++W G +
Sbjct: 931 SVLTD------DVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMD 984
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
I +E V +D ++ TN+ G YT A + G ++ +++ +
Sbjct: 985 IYENEKYEVMQFADGAQILTIRAPTNL---DSGVYTCTAESEHGVSNSSCQVELTISAES 1041
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
P+ E ++ + E V + G K A K + + +
Sbjct: 1042 SPESFEKVE---ITPPEEV----KETGIDDDIEVILKEEVSGTAQIEKREEEFKLLV--- 1091
Query: 794 PKKVKDEGVYTLKAE-NSEGIAE-TSAVITVEEPTEEN----AEPPLFINRFQEITVKEK 847
KV D+ TL A E + E ++ E+ E+N + P F E VKE
Sbjct: 1092 --KVADQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQEPRFETSTDEYHVKEN 1149
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
GTIK+ A ++ +P P + WY E + S+ ++ ++ +++ NV G+Y
Sbjct: 1150 GTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKR-QGGNYFLR 1208
Query: 908 ASNSAGKSSHGARVTID-VEKVTFV 931
A N G+S ++T+D +E VT V
Sbjct: 1209 AHNCHGESILPMKLTVDPIEAVTHV 1233
Score = 83.4 bits (197), Expect = 2e-15
Identities = 142/699 (20%), Positives = 267/699 (38%), Gaps = 68/699 (9%)
Query: 1007 STMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEINS--ETADVVWERDGEIIKPKKNKY 1063
+T+L V+E +F++ L + KE + V +N + + VVW +DG+ ++ K+ Y
Sbjct: 13954 TTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPLEINKD-Y 14012
Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK----VN 1119
+ G L +R D G+Y + C+ +++ P ++ + K V+
Sbjct: 14013 SIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKP--VLKNVSETKPVITVD 14070
Query: 1120 KGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
K ++ + + +A DG +++F ++ + KL DAGEY
Sbjct: 14071 KDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLTKRGVSKTDAGEYEV 14130
Query: 1179 EVGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAY---LTVEIPDETLDVTWY---K 1231
++ N + + + +N T P + +V A +D T D +VT Y K
Sbjct: 14131 KLKN-EFGEVAQKFDVKVNDTPSAPGDVSVVKAESDCLHIEWTAPTEDNGAEVTSYVIEK 14189
Query: 1232 KKS---------VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST---TKL 1279
K+S + + ++ D++ T I + ++ T ++ K +
Sbjct: 14190 KESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFG-TGEFIETKPVQTGSPF 14248
Query: 1280 KVEVVEFPPKIVDY-EREYRIKRGSDV----TLLVDYQAFPQPND-EWI-VNSKIIKKCK 1332
+V VEFPP I + + + + + Y + + N+ EW +N + + +
Sbjct: 14249 QVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDVYKRENEGEWQKMNGEELVFTE 14308
Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
S K +AG L +N ++ V L P + +
Sbjct: 14309 SFNVRALSSGKEYEFKIEACNEAG-----LRSNSNVVSKKLTVEGLVPEIILDMPMVKVL 14363
Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-------KNITKTQTSIQNLKT 1445
D+ + + W ++ G +VV+Y+ ++ W SV ++ ++ I L+
Sbjct: 14364 DNDKVEVTW---KSDGEKE---FVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLRE 14417
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
Y FR A N+ + SE T V+ + +P V K +K + ++ L C
Sbjct: 14418 GIPYVFRVAARNQHGTGEFSEPTIPVVVLAD---DAPRVLKAIKPVKIPKKGELRLECHA 14474
Query: 1506 GGVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
G P P+ WY+DGK++ T + YK + N HG E
Sbjct: 14475 AGHPAPEYIWYKDGKEIIPTDENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAE 14534
Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI-WYKNGNKLENDKEY 1619
+ VGI V N + ++ + + E V+ WYK+G KL
Sbjct: 14535 SEAEVGISD--VRAHFNSSFSELTEIEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRV 14592
Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
+ +RIK + S Y E ++ + EV
Sbjct: 14593 QFYAMARKRTLRIKGSTDADSGVYKCETTDGRSRTEGEV 14631
Score = 82.6 bits (195), Expect = 3e-15
Identities = 108/496 (21%), Positives = 203/496 (40%), Gaps = 54/496 (10%)
Query: 502 TSEEQSMAPIFVEKL--RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
+S S P FV L R HT + + +C+ G P P W + ++ Q +Q+
Sbjct: 3889 SSITSSTRPHFVVPLPERVTHTVNDH-ITIKCKFSGQPLPAAMW-EKDGVLLDLQKYQVT 3946
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH-GSEMT-VXXXX 617
+D + L I +D +TC N AG S++ + V + DH G + T +
Sbjct: 3947 -TEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDV---VDDHLGLQQTGLHVMC 4002
Query: 618 XXXXXXXXADILE----------GIPP---TFSKKPKAQYVDEGSDIL------LECRLV 658
DIL PP T +++P + ++ L+C ++
Sbjct: 4003 ERDQNDVELDILVQSPNHLGVTFNFPPVNRTLARQPPYFLLPLSDKVVIDEKCTLKCVVM 4062
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
IP + W+ G + D+N + E + ++L++ N+KK + A+N +G+
Sbjct: 4063 GIPLVIVKWIVDGVVVTEDDNHEIHFEDGI----ALLRMKNIKK-DKSVVQCEAINCKGK 4117
Query: 719 ASLPIVL------KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
+ VL + + G+ + P + LK + L VVG P P ++ N
Sbjct: 4118 VTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTT-DHATLKCIVVGTPLPDVSCSFNG 4176
Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEG-VYTLKAENSEGIAETSAVITVEEPTEENAE 831
+ DG I +++ V +EG V N G + ++ V+ + + E+N +
Sbjct: 4177 VTDNSKIRSEDG----IVLIQVNDVTEEGIVVECTISNETGSSTSNCVVKIIKQEEKNYQ 4232
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIEL 890
P+ + Q +V + + + V +P P++ W N + I F DG I L
Sbjct: 4233 RPIIVFN-QAGSVNNERELSVKVGVIASPEPTLFWKHNGKSIEEGGDYYLIFEDGIGI-L 4290
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE---KVTFVKHLQKSYETEEGKTVI 947
+ N+ S ++ C+A N G+++ V I ++ K+T VK L ++ +
Sbjct: 4291 KVFNIQD--GSHEFTCIAKNEYGQTTVEIPVEIGLKTENKLTLVKTLNDIAVVDDIVQLK 4348
Query: 948 LECQTSHTVSTKWYHN 963
+ + + KW+ +
Sbjct: 4349 IVAEGDLPIEFKWFED 4364
Score = 82.6 bits (195), Expect = 3e-15
Identities = 108/519 (20%), Positives = 204/519 (39%), Gaps = 34/519 (6%)
Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG-IPPPEVIWYKNGNKLEN 1615
G + ++ +++ PV + K K G E ++ + I +V+W K+G LE
Sbjct: 13949 GTESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLKDGKPLEI 14008
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
+K+Y+I T + + ++ K S KY + ++ + + K K PVI
Sbjct: 14009 NKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTHLSIQGKPVLKNVSETKPVIT 14068
Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
+ + + + +T + E D I V D + + K +
Sbjct: 14069 VDKDDQFSLLVAYDSNPEASFSMTVDG-KDLEFDGRSRIDVVDDGLKLTKRGVSKTDAG- 14126
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
EY ++ + F E + + + D PS +++ ++I W ++
Sbjct: 14127 EYEVKLKNE----FGEVAQKFDVKVN---DTPSAPGDVSVVKA-ESDCLHIEWTAPTEDN 14178
Query: 1796 GSPIIDYKVEIKQEGKK--WKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYT 1852
G+ + Y +E K+ G++ K + + L I T Y RI A N+ GT +
Sbjct: 14179 GAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGTG-EFI 14237
Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
+ G P+ + TS S +L W +P +GGSP+ Y + +K W
Sbjct: 14238 ETKPVQTGSPFQVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDV-YKRENEGEW 14296
Query: 1913 TKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
K+ + S + + + KE + F+I A N G+ + S +L VP
Sbjct: 14297 QKMNGEELVFTESFNVRALSSGKEYE---FKIEACNEAGLRSNSNVVSKKLTVEGLVPEI 14353
Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW--MEVG---KVDVNT 2023
++++ ++ V +W + DG + + + ++W +++G T
Sbjct: 14354 ILDMPMVKVLDNDKVEVTWKS---DGEKEFV---VQYKSDGSSIWASVDIGGPRSESAAT 14407
Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
K I L E Y+ R+ ARN+ G E E P V+
Sbjct: 14408 SKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVVVL 14446
Score = 82.6 bits (195), Expect = 3e-15
Identities = 75/286 (26%), Positives = 121/286 (42%), Gaps = 16/286 (5%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR-WF 1140
H GE+S E V + + P ++ ++ K+ K + E A W+
Sbjct: 14431 HGTGEFS-----EPTIPVVVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWY 14485
Query: 1141 KDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPS 1195
KDG EI + ++ +G L I++ +D G Y V G ++ A + + +
Sbjct: 14486 KDGKEIIPTDENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVR 14545
Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK--KKSVIEDTEKFTLISDVKKRTL 1253
+F E + D LT E+ DE V WYK KK V D +F ++ +KRTL
Sbjct: 14546 AHFNSSFSELTEIEEGHDIELTCEVSDEEAVVNWYKDGKKLVASDRVQFYAMA--RKRTL 14603
Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
I+ T+ D Y C D +S T+ +V V E P I+ ++ +K + +L +
Sbjct: 14604 RIKGSTDADSGVYKCETTDGRSRTEGEVIVNEQEPHILVGPQDAIVKDFGETMVLFCETS 14663
Query: 1314 FPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
P +W N +I + D K A+L IK + D G Y
Sbjct: 14664 KPVRKVKWFKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAY 14709
Score = 78.6 bits (185), Expect = 5e-14
Identities = 63/261 (24%), Positives = 114/261 (43%), Gaps = 7/261 (2%)
Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
N++ + + D W+ V+ E+ + + L + K ++ Y VL
Sbjct: 8780 NSEVIIKCKTSQPISDAKWFCNGMVLLPDEQVNMTVTGCEAVLRLVKFLPQNKGNYH-VL 8838
Query: 1271 LDAKSTTKLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
+D ++ + PP I++ + + G T ++ P P + N + +
Sbjct: 8839 IDGSIGSQPAILSGPVPPVILNKLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVS 8898
Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
K I ASL I K+ D G Y + LEN G + ++++T++D P P K +
Sbjct: 8899 F--DVKYEIYDNIASLYIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKPRKAQL 8956
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSS 1448
+ + +S W P +TG S I++Y+V + ++ W ++ ++ KT T+I+ L N
Sbjct: 8957 VALTDTSATFKW-LPPHTGESDILHYIVMRRSTESRRWRNIGHVQEKTFTAIE-LVPNEF 9014
Query: 1449 YRFRAYAVNEVDISDASETTE 1469
Y FR AVN SE E
Sbjct: 9015 YAFRIVAVNGFGEGAPSEIIE 9035
Score = 77.4 bits (182), Expect = 1e-13
Identities = 68/238 (28%), Positives = 113/238 (47%), Gaps = 23/238 (9%)
Query: 700 VKKFQEGT---YTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
+ + +EGT + V+A N+ G E S I K T K+P P V+ G++
Sbjct: 15557 IAQLKEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTESKKPAFTNAPTDLTAVKNGKT 15616
Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
I +A+ G+P P I W KN K + K ++ S+TI + ++ DEG Y + +
Sbjct: 15617 KI-TAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMRE-DDEGEYKIVVK 15674
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867
N+ G E S +T+++ E N ++R+ V +KG T+KL + P P + W
Sbjct: 15675 NTAGSVEHSCKLTMDQLPEINR-----VDRYASTLVFDKGETVKLRLSFSGRPQPEVIWI 15729
Query: 868 RNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH--GARVT 922
NN ++I S + N L I ++DS+ D G++ N G+ + G +VT
Sbjct: 15730 DNNGKVIEESRKMKIEKTVLNTVLTINSIDSQ-DQGEFALKIKNRCGEDKYAIGIQVT 15786
Score = 75.8 bits (178), Expect = 3e-13
Identities = 127/625 (20%), Positives = 226/625 (36%), Gaps = 65/625 (10%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
DGS ++ P W ++ +Q+ + D++N + + ++ P G T
Sbjct: 608 DGSPLKLRVMASSLPPATFLWMLNNFELRSNQNVTIRNDEENSSEIEFQKA-PN--GNVT 664
Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
AKN G T ++I++ G ++T A I + +P
Sbjct: 665 VSAKNHLGEDRWTGKVILQYESPPPGQKITTIEKVTESWTLEEAVITQVVPTA------- 717
Query: 643 QYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
D G I++ R + W G I E VA+ES + S L + +
Sbjct: 718 --ADPGDRIVIIVRFDENKTSNCQFNWTINGVNIEKLEENLVAVESTE--FESSLIVEKL 773
Query: 701 KKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKE------------PPQVIEPLKSMIVR 747
++ G V N+ GE S L+I+ + P+++EPL S
Sbjct: 774 EEQLCGEVVCVVKNQHGEVFSSSAHLRIRDDDSSFEIVPPNLPEECAPKIVEPLHSASFL 833
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI-----TILKPK-KVKDEG 801
G+++ L ++ NP + W K++ V+ D T + +L P+ +D G
Sbjct: 834 DGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCELLNPECFAEDAG 893
Query: 802 VYTLKAENSEGIAETSAVITVEE----PTEENAE--------------PPLFINRFQEIT 843
+Y A N G AET+A I VE E AE PP FI T
Sbjct: 894 LYKCTATNPHGTAETAAFINVEGAEYIKDHEEAEISESVLTDDVHIILPPKFIETLTAET 953
Query: 844 --VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
++ G +++VA V +++W ++ I +E + +++ + +DS
Sbjct: 954 DNFQQLGYVRMVATVRSVAPITVSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDS 1013
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET------EEGKTVILECQTSHT 955
G Y C A + G S+ +V + + + + +K T E G +E
Sbjct: 1014 GVYTCTAESEHGVSNSSCQVELTISAESSPESFEKVEITPPEEVKETGIDDDIEVILKEE 1073
Query: 956 VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET 1015
VS K+E ++ + V K + + E +
Sbjct: 1074 VSGTAQIEKREEEFKLLVKVADQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQ 1133
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
P F ++ VKE + I+ T + W E ++ +N + + G +
Sbjct: 1134 EPRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAG-TSAI 1192
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE 1099
++N G Y LR +C E
Sbjct: 1193 ILKNVQKRQGGNY--FLRAHNCHGE 1215
Score = 74.9 bits (176), Expect = 6e-13
Identities = 71/262 (27%), Positives = 110/262 (41%), Gaps = 22/262 (8%)
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
R++ ++++ + R+ A + +G + +I + K + PS P + E T SV L
Sbjct: 14789 RMKDVTLDNSGTVRVIAESPLGQCIK-----EIPL-KIIDKPSAPCDLQFKEVTEDSVFL 14842
Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
W P G+P+T Y+IE K V W V + E++ FRI A N
Sbjct: 14843 SWQPPLETNGAPLTGYVIERKAVDNNRWRPCGQVKPTKLTFVAEDLFCNQVYGFRILAVN 14902
Query: 1945 TVGVSLPTESQSV-RLEKHATVPS------PPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
VG S P ++ V LE V P A L V + T T W+
Sbjct: 14903 EVGESEPCDTVDVLTLESSEPVSESSELFVPKIAILRTPQVTVAVDETKV-TLRWEECPE 14961
Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
Y + + V + W+E+ D N KF R L+E+ Y+ ++ A +S P E
Sbjct: 14962 TSLYKVERKKVGDSDWLEIANTDRN--KFKDRSLTESGEYVYQVTATGIHAVSSPSEETN 15019
Query: 2058 PFKV-IPGEGSHADEEPGEQTE 2078
P K+ +PG E P +TE
Sbjct: 15020 PVKILVPG-----SEMPASKTE 15036
Score = 74.1 bits (174), Expect = 1e-12
Identities = 64/270 (23%), Positives = 113/270 (41%), Gaps = 11/270 (4%)
Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
I + A + ++ ++ + + V W K ++ + +T+ S T+ I +
Sbjct: 15199 IELTAGKEGEISAQVAETGVSVEWKKDGKALDAS--YTVTSTGGVSTVKIPIVDVNTSGV 15256
Query: 1266 YTCVLLDAKSTTK-LKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWI 1322
+TC + ++ + + + V P++ E E I + DV L + P + W
Sbjct: 15257 FTCKVKSSEGDEEEVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISEPASSVNWT 15316
Query: 1323 VNSKIIKKCKHTKPSIDSK-SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK- 1380
+ K IK+ + K + +A LTI K ++ +GIYKL +EN+ G VE+ + I
Sbjct: 15317 KDDKPIKEDGNVKAQLSPDGTAQLTISKTDSAHSGIYKLNVENDAGKGKVEIALRIKGAA 15376
Query: 1381 ---PSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
P P P + + + SS W PEN G I Y VE +E W +
Sbjct: 15377 KGAPGIPTGPIVFDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQCGKTKEL 15436
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
+ L+ + Y + AVN + A E
Sbjct: 15437 KFKADGLEEGTDYDVKVSAVNTMGTGSALE 15466
Score = 73.7 bits (173), Expect = 1e-12
Identities = 79/303 (26%), Positives = 125/303 (41%), Gaps = 24/303 (7%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIES 686
+L P K K + + ++ LEC P P+ W G+EI+P DEN + E
Sbjct: 14445 VLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNEG 14504
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
M S L I + G Y V+ N G A + I L +
Sbjct: 14505 SM----SALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELTE--I 14558
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITI-LKPKKVKDEGVYT 804
+G + L+ + V + + W K+ K + A + T+ +K D GVY
Sbjct: 14559 EEGHDIELTCE-VSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADSGVY- 14616
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
K E ++G + T + V E EP + + Q+ VK+ G ++ T PV +
Sbjct: 14617 -KCETTDGRSRTEGEVIVNE-----QEPHILVGP-QDAIVKDFGETMVLFCETSKPVRKV 14669
Query: 865 TWYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
W++N I P ++ I +N DG+ L I N D D G Y AS S ++S A++
Sbjct: 14670 KWFKNGVEIWPQMNKAIMEN-DGKRATLEIKNFDKH-DIGAY--TASVSEKETSAPAKLV 14725
Query: 923 IDV 925
+V
Sbjct: 14726 FEV 14728
Score = 73.3 bits (172), Expect = 2e-12
Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 12/167 (7%)
Query: 1800 IDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
ID ++ +E +K K I + +F + +N G +DK I
Sbjct: 15729 IDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFALKIKNRCG-------EDKYAI 15781
Query: 1860 GKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VT 1917
G +T P+ P V + SV L+W P ++GGSP+ NY +E T KGK+WTK VT
Sbjct: 15782 GIQVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWTKAEVT 15841
Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ + N+ + FR+ A+NT G S P++ + + K+ +
Sbjct: 15842 KQAFI---TLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVS 15885
Score = 72.9 bits (171), Expect = 2e-12
Identities = 89/420 (21%), Positives = 167/420 (39%), Gaps = 33/420 (7%)
Query: 1274 KSTTKLKV--EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-K 1330
+ T+K+ V E+++ PP ++ K G L+V P+P +W N + I
Sbjct: 16382 RKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISIN 16441
Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKP 1387
+ D L I V++TD G +K +N G + E +T++ + +P
Sbjct: 16442 DSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGK 16501
Query: 1388 NILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNL 1443
+ ++ S +I E N + I + EI+ ++ ++ +I +
Sbjct: 16502 QLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDA 16561
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVI--KETKI---QSPTVEKPLKNITTEPN-E 1497
S ++ A N++ + +++ + KI ++P L P
Sbjct: 16562 YAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGA 16621
Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRX-XXXXXXXXXXXXXXYKCIAFN 1554
D+ L C G P P + W +D K + + + +EN Y C A N
Sbjct: 16622 DLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGRYVCEAEN 16681
Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKV---------GDEWLVTAVIEGIPPPEVI 1605
HG ++ VV I++ + + ++ K G+E ++ + G P P +
Sbjct: 16682 IHGVAQSFSVVEIKE----AVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTIT 16737
Query: 1606 WYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
WYK+G KL ++ T ++ S + I + + +YT EA N+ G T+KV D
Sbjct: 16738 WYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 16797
Score = 72.1 bits (169), Expect = 4e-12
Identities = 102/420 (24%), Positives = 173/420 (41%), Gaps = 44/420 (10%)
Query: 1002 KDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK 1057
KD++TS ++V++E I P F LQD E K + IL V + V W +GE I
Sbjct: 16380 KDRKTSKVVVIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHIS 16439
Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAE--VTVV----ELPPEI 1109
+ Y + +L+I + DEG++ + ++ C +E +TVV + P
Sbjct: 16440 INDSNYLRKHDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSF 16499
Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID--GKKQKLKIY 1166
+L + K ++ + E+ + A + WF++ SEI+ S H +L D L I
Sbjct: 16500 GKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTII 16559
Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEE------------PSINFTLRLPEFILVPA 1210
D +D+GEY C ++G + + +EE + F ++LP VP
Sbjct: 16560 DAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQ 16619
Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
D L + ++ W K I+ + K + + TL I +DDQ Y C
Sbjct: 16620 GADLTLVCSVSGTPHPNIKWTKDDKPIDMSNK-QVRHENGVCTLHIIGARDDDQGRYVCE 16678
Query: 1270 ------LLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
+ + S ++K V+ PK ++ G+++ L P P W
Sbjct: 16679 AENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITW 16738
Query: 1322 IVNS-KIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
+ K+I + + + + D K S L I V D G Y N+ G V ++D
Sbjct: 16739 YKDGLKLIIENRMLQYT-DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVKVVD 16797
Score = 70.9 bits (166), Expect = 9e-12
Identities = 55/202 (27%), Positives = 85/202 (42%), Gaps = 19/202 (9%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536
+P + L + N + L +F GVPQP ++W D +L + EN
Sbjct: 3788 APVFTERLPSSACFANSKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAI 3847
Query: 1537 XXXXXXXXXXXY-KCIAFNDHGEVETSC-VVGIQQKPVITISNEDIKQK----------- 1583
+ KC A N G+VETSC +V + VI+ S+ +
Sbjct: 3848 RFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERV 3907
Query: 1584 -HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
H V D + G P P +W K+G L+ K Y +TT++ TS+++I+ +
Sbjct: 3908 THTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQK-YQVTTEDGTSILKIESASLDDKAV 3966
Query: 1643 YTIEASNTAGTSSVEVTLKVYD 1664
YT +N AG S T+ V D
Sbjct: 3967 YTCTIANEAGCESTSCTIDVVD 3988
Score = 70.5 bits (165), Expect = 1e-11
Identities = 75/349 (21%), Positives = 142/349 (40%), Gaps = 28/349 (8%)
Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
H+ G + G P P + NG + D +Y I + + + I ++ + +Y
Sbjct: 8868 HQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIY--DNIASLYIPKMSKRDGGEY 8925
Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
T+ N G ++ + + D P KP ++ ++ S T +W PP G ++ Y +
Sbjct: 8926 TVVLENKYGKDESDLHITMVDTPLKPRKAQLV-ALTDTSATFKWLPP-HTGESDILHYIV 8983
Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT- 1762
+ ++ RW + V +T+ +L N Y FR++A N GF E SE I + T
Sbjct: 8984 MRRSTESRRWRNIGHVQE--KTFTAIELVPNEFYAFRIVAVN--GFGEGAPSEIIEVNTL 9039
Query: 1763 ------ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
+ D ++NE +T E++ I+ ++K++ KK K
Sbjct: 9040 DYDQEESFDFAGEEELKLDDVQVNNE--VVTEITIEES--EVTIEEHRKLKKKSKKSKKT 9095
Query: 1817 XXXXXXXARIQ-KLSINTTYQFRIYARNEIGTSLPYTSD--------DKITIGKTLTPPS 1867
+ I ++S + T I + I + P + + + T+ K P
Sbjct: 9096 TDEPELDSEIALEVSSDITSSLEITTESTIPDTAPESQETLNVEIAVTETTVQKITNPSD 9155
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
+ V+E T+ S +K + + N S + + K ++GK KI+
Sbjct: 9156 ESAKKDVNEDTAVSSIVKKDDKDVNKKSLPESGLTTKKEIQGKPEKKIM 9204
Score = 70.1 bits (164), Expect = 2e-11
Identities = 80/320 (25%), Positives = 121/320 (37%), Gaps = 42/320 (13%)
Query: 1480 QSPTVEKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538
Q PT K L+++ + E TC P +V W +GK L+ K+ Y+ R
Sbjct: 16930 QMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNT 16989
Query: 1539 XXXXXXXXX------YKCIAFNDHGEVETSCVVGIQQKPVITISNE------DIKQKHKV 1586
Y +A N G+V TS + I I+ ++K K V
Sbjct: 16990 ATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINV 17049
Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G + A + G P PEV+W K+ ++L + + ++++ YT
Sbjct: 17050 VEGATLSIQADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYT 17109
Query: 1645 IEASNTAG----------TSSVEVTLKVYDK-----------PSKPEGPVIMREISRESV 1683
I A N G T S EV K K P +P P E V
Sbjct: 17110 ITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPSGASKTEQV 17169
Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
T+ + P +G + Y +E+ PD W+ + +E I+ L N EY+FRV
Sbjct: 17170 TMAFDAP-SEGPAD--SYEVERRCPDQREWVSCGST-KSLELE-IKGLTPNTEYIFRVAG 17224
Query: 1744 QNPVGFSEALESEPIVIKTA 1763
+N G E E +KTA
Sbjct: 17225 KNKQGLGEWSEMTS-TLKTA 17243
Score = 70.1 bits (164), Expect = 2e-11
Identities = 106/437 (24%), Positives = 167/437 (38%), Gaps = 56/437 (12%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F+ K + +V E+ ++ L+ I+ V W+++G II NKY G L
Sbjct: 18008 PKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG-IILETGNKYSIYNDGDFYYL 18066
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL 1130
+ + S D+G Y+C + +CT+E+ V+ + ++ +K K KA IE+
Sbjct: 18067 EVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEV 18126
Query: 1131 TKG------------DALVRWFKDGSEIQFSNHIQL---------TIDGKKQKLKIYDCD 1169
G + V + S I N ++L + DG+ LK
Sbjct: 18127 LPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVT 18186
Query: 1170 LDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFIL---------VPANTDAYL 1216
D G Y+CE N +A+ L V N +P V + L
Sbjct: 18187 PGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVEL 18246
Query: 1217 TVEI--PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272
E+ E L + W + K I D+ F+ L I +D EYT +
Sbjct: 18247 AAELVQASEPLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQS 18306
Query: 1273 --AKSTTKLKVE-----VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VN 1324
A+ T +L V V + P++ D+E R G V L P P W
Sbjct: 18307 GIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAG 18366
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K+ + K+ + K L I V DAG Y+L N G A+ E+ +T++
Sbjct: 18367 QKLNNEEKYMMRNEGDKFI-LRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTV 18425
Query: 1385 G-KPNILEIDSSSINIC 1400
G KP E S+ C
Sbjct: 18426 GAKPKFNE-SPISVQTC 18441
Score = 68.1 bits (159), Expect = 6e-11
Identities = 63/273 (23%), Positives = 109/273 (39%), Gaps = 8/273 (2%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXX 1538
SP + +P+ TE + + T F P V W RD ++++ A KA+ E
Sbjct: 10273 SPFISQPVSATVTEMAGEAKFTVKFSRKPI-YVKWMRDDREIRVAYGKASVETTDDSSVL 10331
Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
I E ++ + ++ IT+ + + G ++ I
Sbjct: 10332 VIKNIDGKDVGNIYAVFDSEYRSAMARLDLRVPCKITLESSSNAPEIVAGKNLDLSFKIS 10391
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P I + N+ + ++T + + IR+K LK S + I N + +
Sbjct: 10392 GYPLPTNIELLHNNENLRTRS-DVTDFDDSISIRMKRLKLEDSGEIKIIGKNDSSEDQLR 10450
Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+ + V + SKP + + RE+VT+ W P + G + +Y +E+ D RW
Sbjct: 10451 IPINVIEVTSKPTS-LQVTSTERETVTLTWSLPTELNGSNVNEYLVERKTVDGGRWRHAC 10509
Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
V + L EY+FRV+A N G S
Sbjct: 10510 TVTD--SRAVVDGLFSGTEYVFRVVAVNGAGQS 10540
Score = 66.1 bits (154), Expect = 3e-10
Identities = 57/283 (20%), Positives = 116/283 (40%), Gaps = 15/283 (5%)
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
D + V + K D +I ++ + + D + LD + K+ +
Sbjct: 10310 DREIRVAYGKASVETTDDSSVLVIKNIDGKDVGNIYAVFDSEYRSAMARLDLRVPCKITL 10369
Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
E P+IV G ++ L +P P + ++++ + + D
Sbjct: 10370 ESSSNAPEIV---------AGKNLDLSFKISGYPLPTNIELLHNNENLRTRSDVTDFDD- 10419
Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
S S+ +K+++ D+G K+ +N+ + + + +++ S P + + ++ + W
Sbjct: 10420 SISIRMKRLKLEDSGEIKIIGKNDSSEDQLRIPINVIEVTSKPTSLQVTSTERETVTLTW 10479
Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
P S + Y+VE + +D W +T ++ + L + + Y FR AVN
Sbjct: 10480 SLPTELNGSNVNEYLVERKTVDGGRWRHACTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQ 10539
Query: 1462 SDASE----TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
S S+ TT+ + I ET SP VEK + ++ +P E
Sbjct: 10540 SAPSDTIEATTQAEEEIDETVPTSP-VEKVKEPVSKKPENTKE 10581
Score = 65.3 bits (152), Expect = 5e-10
Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 9/157 (5%)
Query: 802 VYTLKAENSEG---IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
++ + A+N G +E S I ++ TE ++ P F N ++T + G K+ A T
Sbjct: 15567 LFRVIAQNKTGQTVTSEQSESIECKDTTE--SKKPAFTNAPTDLTAVKNGKTKITAEFTG 15624
Query: 859 NPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
+P P I W++N EI S +N G L I + E D G+YK V N+AG H
Sbjct: 15625 HPAPEIHWFKNKKEIFSGKRQWIENIAGAT-SLTIGEM-REDDEGEYKIVVKNTAGSVEH 15682
Query: 918 GARVTID-VEKVTFVKHLQKSYETEEGKTVILECQTS 953
++T+D + ++ V + ++G+TV L S
Sbjct: 15683 SCKLTMDQLPEINRVDRYASTLVFDKGETVKLRLSFS 15719
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/247 (25%), Positives = 96/247 (38%), Gaps = 20/247 (8%)
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
KT+ + +A N I++ + K + +P PL ++ L+C
Sbjct: 17638 KTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSC 17697
Query: 1504 IFGGVPQPKVTW-YRD--GKKLKTAKAT-------YENRXXXXXXXXXXXXXXXYKCIAF 1553
G P+P + W Y D G K+ +T + Y+CIA
Sbjct: 17698 NVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIAT 17757
Query: 1554 NDHGEVETSC--VVG-IQQKPV----ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
N G+ T C +VG + +P +D K E+ V + G P P++ W
Sbjct: 17758 NSSGQATTQCYLLVGELSDEPAGPPRFVKCLQDTWTPLKESIEFSVE--LAGFPTPDLTW 17815
Query: 1607 YKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
Y N K+ K+ IT + TSV+ IK + + Y +EASN G L V D+
Sbjct: 17816 YHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEASNIHGVLRTAGRLNVSDE 17875
Query: 1666 PSKPEGP 1672
K E P
Sbjct: 17876 RRKAEPP 17882
Score = 62.5 bits (145), Expect = 3e-09
Identities = 39/152 (25%), Positives = 75/152 (49%), Gaps = 11/152 (7%)
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRNFVVSESTSRSVT 1883
R+++L + + + +I +N+ +S+D++ I + S+P + V+ + +VT
Sbjct: 10424 RMKRLKLEDSGEIKIIGKND-------SSEDQLRIPINVIEVTSKPTSLQVTSTERETVT 10476
Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
L W+ P GS + Y++E KTV G W TV S ++ + E +FR+ A
Sbjct: 10477 LTWSLPTELNGSNVNEYLVERKTVDGGRWRHACTVTDS--RAVVDGLFSGTEYVFRVVAV 10534
Query: 1944 NTVGVSLPTESQSVRLEKHATV-PSPPTAPLE 1974
N G S P+++ + + + PT+P+E
Sbjct: 10535 NGAGQSAPSDTIEATTQAEEEIDETVPTSPVE 10566
Score = 61.7 bits (143), Expect = 6e-09
Identities = 121/594 (20%), Positives = 223/594 (37%), Gaps = 57/594 (9%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP+F E+L S + E G P+P I+W + + ++ V+ +
Sbjct: 3788 APVFTERLPSSACFANSKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAI 3847
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE---APLSDHGSEMTVXXXXXXXXXXXX 625
V G C A N AG ++ E++ + +SD +
Sbjct: 3848 RFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERV 3907
Query: 626 ADILEG---IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE---- 678
+ I FS +P + E +LL+ + + D + K E D+
Sbjct: 3908 THTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKYQVTTEDGTSILKIESASLDDKAVY 3967
Query: 679 NISVAIESDMH-MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---------- 727
++A E+ C++ + + Q+ V+ + + L I+++
Sbjct: 3968 TCTIANEAGCESTSCTIDVVDDHLGLQQTGLHVMCERDQNDVELDILVQSPNHLGVTFNF 4027
Query: 728 ----KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783
+T ++PP + PL +V E L V+G P + W + V
Sbjct: 4028 PPVNRTLARQPPYFLLPLSDKVVID-EKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEI 4086
Query: 784 GDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVIT---VEEPTEENAEPPLFINRF 839
I +L+ K + KD+ V +A N +G TS V+T VEE + + P F+
Sbjct: 4087 HFEDGIALLRMKNIKKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSL 4146
Query: 840 QE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
++ T + T+K + V P+P ++ N ++ + I ++ DG +V+ V+
Sbjct: 4147 KDTCTTTDHATLKCI--VVGTPLPDVSCSFNG--VTDNSKI-RSEDG----IVLIQVNDV 4197
Query: 899 IDSG-DYKCVASNSAGKSSHGARVTI------DVEKVTFVKHLQKSYETEEGKTVILECQ 951
+ G +C SN G S+ V I + ++ V + S E +V +
Sbjct: 4198 TEEGIVVECTISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVI 4257
Query: 952 TSHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETST 1008
S + W HN K I G D+ I ++G CI K++ +T+
Sbjct: 4258 ASPEPTLFWKHNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSH--EFTCIAKNEYGQTTV 4315
Query: 1009 MLVVK-----ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
+ V+ E ++ L D V + V + V + W DG+I++
Sbjct: 4316 EIPVEIGLKTENKLTLVKTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILE 4369
Score = 60.9 bits (141), Expect = 1e-08
Identities = 58/218 (26%), Positives = 99/218 (45%), Gaps = 21/218 (9%)
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHS--ITILKPKKVKDE 800
+G+ V+ + +VV + P I +N+ PV A + G HS +TI +K+ D
Sbjct: 12187 EGDVVVFTIKVVSDDVPLIRMYRNDFPVANFDKMAFEGFTKGSEHSFNVTINDIRKL-DG 12245
Query: 801 GVYTLKAENSEGIAETSAVITVEEP---TEENAE---PPLFINRFQEITVKEKGTIKLVA 854
G +A+N G+ + + ++ V + E+ +E N ++ VKE T KL
Sbjct: 12246 GKLVFEAKNDYGVDKCTILLDVRDSGSFIEDYSEIHRSAEIQNSVGDVQVKEGETAKLTG 12305
Query: 855 RVTRNPVPSITWYRNN---EIISPSETITQNF--DGENIELVITNVDSEIDSGDYKCVAS 909
RV P+P + W +N +++ PS ++ DGE E I N E D DY +
Sbjct: 12306 RVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGE-FEARIANCTFE-DDDDYSLLVE 12363
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
N AG S +V +D + +H + + G+ V+
Sbjct: 12364 NLAGVDSCNFQVFVDCNEYPDDEHFNRRRRLQRGRRVM 12401
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/301 (22%), Positives = 121/301 (40%), Gaps = 24/301 (7%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+TA G P PE+ W+KN ++ + K I + + I E++ +Y I NTA
Sbjct: 15618 ITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMREDDEGEYKIVVKNTA 15677
Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
G SVE + K+ + + P I R + R + T+ + D G + +
Sbjct: 15678 G--SVEHSCKL----TMDQLPEINR-VDRYASTLVF----DKGETVKLRLSFSGRPQPEV 15726
Query: 1712 RWI----KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKTALDV 1766
WI KV + R ++ I+K N I G F+ +++ K A+ +
Sbjct: 15727 IWIDNNGKVIEESRKMK---IEKTVLNTVLTINSIDSQDQGEFALKIKNRCGEDKYAIGI 15783
Query: 1767 P-SXXXXXXXXXXIDNE---SVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXX 1821
+ ++++ SV + W +GGSP+ +Y VE+ ++GK W
Sbjct: 15784 QVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWTKAEVTKQ 15843
Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
+ L +Y+FR+ A N G S P + + + +P+ V S
Sbjct: 15844 AFITLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVSRVVEEPKKKEVKVKEQES 15903
Query: 1882 V 1882
V
Sbjct: 15904 V 15904
Score = 58.8 bits (136), Expect = 4e-08
Identities = 133/587 (22%), Positives = 225/587 (38%), Gaps = 86/587 (14%)
Query: 1017 PEFIRKLQDFEVKEKDVAI-LEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
P+F Q + +D + VE + + T V W ++ I P + K D L
Sbjct: 17249 PQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDE-KIDVATTSTSSIL 17307
Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PE------IITRLQNQKV 1118
++ S + G ++C++ +E S + +VT+ P P+ ++ LQ
Sbjct: 17308 NLK--SQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALN 17365
Query: 1119 NKGNKATFEIELT-----KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDD 1172
N+ +A +I LT + ++ V WFKD I+ + +L+ D K KL + D
Sbjct: 17366 NESAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQD 17425
Query: 1173 AGEYSCEVGN------SKCT-AILTVEE---PSINFTLRLPEFILVPANTDAYLTVEIPD 1222
G+Y C V N S+C A+ V + PS + TL IL N VE
Sbjct: 17426 TGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAIL-GHNITLECKVE-GS 17483
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTC------------- 1268
+V+W K I T + D L I K DD Y C
Sbjct: 17484 PAPEVSWTKDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSS 17543
Query: 1269 VLLDAKST-TKLKVEVVEFPPKIVDYEREYR-------IKRGSDVTLLVDYQAFPQPNDE 1320
+++ AK+T T + + + + + R R + TL+ P+P
Sbjct: 17544 MVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVT 17603
Query: 1321 WIVNSKIIKKCK---HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W+ + + I + H + D +S L + V + +GI+ + EN G E V I
Sbjct: 17604 WLKDGREILRTNRIYHHFVTGDGES-HLIAECVVSKTSGIFSCKAENPNGTVIAETQV-I 17661
Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK------ 1431
+ + P + + + D G+ T + V T EWI +
Sbjct: 17662 VQRMKPANQ--LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKI 17719
Query: 1432 NITKTQTS--------IQNLKTNSSYRFRAYAVNEVDISDASE-TTEYYKVIKETKIQS- 1481
N+T + T + LK+ R + + + + + TT+ Y ++ E +
Sbjct: 17720 NLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPA 17779
Query: 1482 --PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P K L++ T E IE + G P P +TWY + KK+ K
Sbjct: 17780 GPPRFVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGK 17826
Score = 57.2 bits (132), Expect = 1e-07
Identities = 88/393 (22%), Positives = 140/393 (35%), Gaps = 37/393 (9%)
Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTL 1660
V W K+G L D Y +T+ S ++I + + S +T + ++ G S+ VT+
Sbjct: 15220 VEWKKDGKAL--DASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVKSSEGDEEEVSIAVTV 15277
Query: 1661 KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720
K+ + P I+ + + K + TK E N +K
Sbjct: 15278 KLPEVPKVEAEQSIVEVKVGDVAKLSAKISEPASSVNWTKDDKPIKEDGN---VKAQLSP 15334
Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
I K + ++++ +N G + +E + A P +
Sbjct: 15335 DGTAQLTISKTDSAHSGIYKLNVENDAGKGK-VEIALRIKGAAKGAPGIPTGPIVFDDVT 15393
Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839
S +W E NGG I Y VE K+ + K WK + L T Y ++
Sbjct: 15394 ESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQCGKTKELKFKADGLEEGTDYDVKV 15453
Query: 1840 YARNEIGTSLPY-----TSDDKITIGKTLTPPSQP-----RNFVVSE-----------ST 1878
A N +GT T K GK + S+ + VSE ST
Sbjct: 15454 SAVNTMGTGSALEGKITTLKKKEETGKQKSEKSESDEKKSESDKVSELKQIGKPEYVSST 15513
Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
+ S+ LKWT Y ++ K K +V S I +KE +F
Sbjct: 15514 ATSIALKWTSDNDE-----VTYTVQMKEANSKRPWAVVAKEISECSATIAQLKEGTSYLF 15568
Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971
R+ A+N G ++ T QS +E T S A
Sbjct: 15569 RVIAQNKTGQTV-TSEQSESIECKDTTESKKPA 15600
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 24/204 (11%)
Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENI 1930
V + T S W PE+NGG IT Y +E K K K W + G E + +
Sbjct: 15388 VFDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQC----GKTKELKFKADGL 15443
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV-------------PSPPTAPLEIRM 1977
+E + ++SA NT+G E + L+K S E++
Sbjct: 15444 EEGTDYDVKVSAVNTMGTGSALEGKITTLKKKEETGKQKSEKSESDEKKSESDKVSELKQ 15503
Query: 1978 VGSNIVMTSWGTP---EWDGGAPLLGYNIAIRDV-TKTMWMEVGKVDVNTLKFNIRDLSE 2033
+G ++S T +W + Y + +++ +K W V K +++ I L E
Sbjct: 15504 IGKPEYVSSTATSIALKWTSDNDEVTYTVQMKEANSKRPWAVVAK-EISECSATIAQLKE 15562
Query: 2034 NHTYMIRIYARNEIGLSEPLESDE 2057
+Y+ R+ A+N+ G + E E
Sbjct: 15563 GTSYLFRVIAQNKTGQTVTSEQSE 15586
Score = 56.4 bits (130), Expect = 2e-07
Identities = 50/205 (24%), Positives = 95/205 (46%), Gaps = 11/205 (5%)
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLK--NITTEPNEDIELTCIFGGV--PQP 1511
V E IS+ + ++ V+K K + ++P+ N N + EL+ G + P+P
Sbjct: 4203 VVECTISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEP 4262
Query: 1512 KVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVG 1566
+ W +GK ++ Y E+ + CIA N++G+ VE +G
Sbjct: 4263 TLFWKHNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSHEFTCIAKNEYGQTTVEIPVEIG 4322
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
++ + +T+ + + V D + V EG P E W+++G LE+D + IT +
Sbjct: 4323 LKTENKLTLV-KTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKC 4381
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTA 1651
S +++K L+ + + T E SN++
Sbjct: 4382 ISTLQLK-LEETGTRIITCEVSNSS 4405
Score = 56.4 bits (130), Expect = 2e-07
Identities = 71/365 (19%), Positives = 133/365 (36%), Gaps = 27/365 (7%)
Query: 1313 AFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
A+P + W NS +++ + S D + ASL V D G Y N G A
Sbjct: 18147 AYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVT 18206
Query: 1372 EMNVTI--LDKPSPPGKPNILE----------IDSSSINICWDEPENTGNSTIIYYVVEY 1419
MN+ + +D + G P + +D S + + + + + I + +
Sbjct: 18207 NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKV 18266
Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
+D+ + ++ +I ++ + A N+ I+ + + +
Sbjct: 18267 TIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVAD 18326
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXX 1535
++P V ++P +EL G P P ++W + G+KL K ++
Sbjct: 18327 EAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFIL 18386
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-------KPVITISNEDIKQKHKVGD 1588
Y+ A N G+ + + Q KP S ++ K
Sbjct: 18387 RIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRA 18446
Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
E + A G P P W+ NGN+L + + Y IT+ + S + I + + H +Y
Sbjct: 18447 E--LRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKHFGEYLCTI 18504
Query: 1648 SNTAG 1652
N G
Sbjct: 18505 RNQNG 18509
Score = 56.0 bits (129), Expect = 3e-07
Identities = 85/380 (22%), Positives = 153/380 (40%), Gaps = 40/380 (10%)
Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA------ 1098
A ++W R+ + P+ ++Y G L + + DEG Y+C +E +A
Sbjct: 18151 ASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAVTNMNL 18210
Query: 1099 EVTVVE------LPPEI-ITRLQN-QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQF 1148
+V+ V+ +PP ++++ +KV G++ EL + +RW ++ I
Sbjct: 18211 QVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPLQIRWLRNKVTIVD 18270
Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPE 1204
S + L I D +D GEY+ E N ++CT L V + P
Sbjct: 18271 SPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSVADEAPR 18330
Query: 1205 -FILVP-ANTDAYLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
F P +D ++VE+ + + ++W K + + EK+ + ++ K L I
Sbjct: 18331 VFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIAN 18390
Query: 1258 CTEDDQCEY--TCVLLDAKSTTKLKVEVVE------FPPKIVDYEREYRIKRGSDVTLLV 1309
T D +Y T + ++ +L++ VV+ PK + + + L
Sbjct: 18391 VTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPKFNESPISVQTCEKNRAELRA 18450
Query: 1310 DYQAFPQPNDEWIVN-SKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
+ P P W N +++I +T S D+ S SL I V+ G Y + N G
Sbjct: 18451 SFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNS-SLLINSVDKKHFGEYLCTIRNQNG 18509
Query: 1368 HADVEMNVTILDKPSPPGKP 1387
+ N IL + S P
Sbjct: 18510 --EELANAMILSEGSSAALP 18527
Score = 55.6 bits (128), Expect = 4e-07
Identities = 83/409 (20%), Positives = 154/409 (37%), Gaps = 36/409 (8%)
Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
+ D + + + + + +++ + KP+ IT + ++ L + P+ + DGK
Sbjct: 14039 VCDGVDCSTHLSIQGKPVLKNVSETKPV--ITVDKDDQFSLLVAYDSNPEASFSMTVDGK 14096
Query: 1521 KL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
L ++ ++ Y+ N+ GEV V + P
Sbjct: 14097 DLEFDGRSRIDVVDDGLKLTKRGVSKTDAGEYEVKLKNEFGEVAQKFDVKVNDTPSAPGD 14156
Query: 1577 NEDIKQKHK-VGDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
+K + + EW G VI K + + K + K+ + V+ E
Sbjct: 14157 VSVVKAESDCLHIEWTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLE 14216
Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKP 1689
++ + + I A N GT T V + P+ E P + ++ S ++ W
Sbjct: 14217 IETPYIVR--IAAVNKFGTGEFIETKPVQTGSPFQVPTV-EFPPTIDNVTSTSCSLSWPK 14273
Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD-VETYCIQKLNENCEYMFRVIAQNPVG 1748
P++DGG + Y + K E + W K+ + E++ ++ L+ EY F++ A N G
Sbjct: 14274 PIEDGGSPVYGYDVYKRE-NEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAG 14332
Query: 1749 FSEALESEPIVIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
S + K ++ VP +DN+ V +TW K+ G ++ V+
Sbjct: 14333 LRS--NSNVVSKKLTVEGLVPEIILDMPMVKVLDNDKVEVTW----KSDGEK--EFVVQY 14384
Query: 1807 KQEGKK-WKX-------XXXXXXXXARIQKLSINTTYQFRIYARNEIGT 1847
K +G W I L Y FR+ ARN+ GT
Sbjct: 14385 KSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIPYVFRVAARNQHGT 14433
Score = 55.2 bits (127), Expect = 5e-07
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S AP F+ KL G VQ +C + G P+P+I W I P+ ++ + Y +
Sbjct: 1672 SSAAPQAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVY-E 1730
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAG 590
D V L I ED G + C A N AG
Sbjct: 1731 DGVCILRIESTLIEDEGEYCCTASNVAG 1758
Score = 54.8 bits (126), Expect = 6e-07
Identities = 59/260 (22%), Positives = 104/260 (40%), Gaps = 22/260 (8%)
Query: 1804 VEIKQEGK----KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
VE K++GK + +I + +NT+ F ++ G +++++I
Sbjct: 15220 VEWKKDGKALDASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVKSSEG------DEEEVSI 15273
Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTL----KWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
T+ P P+ V +E + V + K + S S + N+ + K +K K
Sbjct: 15274 AVTVKLPEVPK--VEAEQSIVEVKVGDVAKLSAKISEPASSV-NWTKDDKPIKEDGNVKA 15330
Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT-VPSPPTAPLE 1974
+ I I++++ EN G ++R++ A P PT P+
Sbjct: 15331 QLSPDGTAQLTISKTDSAHSGIYKLNVENDAGKG--KVEIALRIKGAAKGAPGIPTGPIV 15388
Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
V + SW PE +GG + GYN+ ++ W + GK LKF L E
Sbjct: 15389 FDDVTESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQCGK--TKELKFKADGLEEG 15446
Query: 2035 HTYMIRIYARNEIGLSEPLE 2054
Y +++ A N +G LE
Sbjct: 15447 TDYDVKVSAVNTMGTGSALE 15466
Score = 54.8 bits (126), Expect = 6e-07
Identities = 165/857 (19%), Positives = 306/857 (35%), Gaps = 104/857 (12%)
Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF------RQTAIIKPS 553
KP ++ ++AP F L +G C V G P P + W + + +
Sbjct: 17666 KPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSST 17725
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
D+ VA L V E GT+ C+A N++G A++ L+V LSD +
Sbjct: 17726 TDWTECRFG-KVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLV-GELSDEPAGPPR 17783
Query: 614 XXXXXXXXXXXXADILE------GIP-PTFSKKPKAQYVDEGSDILLE-----CRLVAIP 661
+ +E G P P + + ++EG D+ + +++I
Sbjct: 17784 FVKCLQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIK 17843
Query: 662 EPDIAWLFKGEEIVPDENISVAIE-------SDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
+A L G V NI + SD + +V + VA +
Sbjct: 17844 NVSLASL--GMYFVEASNIHGVLRTAGRLNVSDERRKAEPPQFKHVLEPVLAVQPKVAFS 17901
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-NK 773
E + + + P ++ L+ M ++ G S ++ ++ RP + + +K
Sbjct: 17902 EEHPRASSSAATARVKKGAAPMFLQGLEDMDLKAGASAAVAGKLGRKLRPHRSTTNDADK 17961
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
KAL S+ + +P+ D + E++ A + + P
Sbjct: 17962 LAKAL-------AQSLRLDEPRASIDS-----RPESAANAALDEVRAAINSRNKRVCRPK 18009
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
+ ++E +++L ++ NP+P + W + I+ + DG+ L +
Sbjct: 18010 FMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVH 18069
Query: 894 NVDSEIDSGDYKCVASNSAG-------------KSSHGARVT-----IDVEKVTFVKHLQ 935
+V S D G Y C A+N+ G K A+V + + F++ L
Sbjct: 18070 HV-STFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLP 18128
Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXX 992
+ +++ +EC S S W N + + D + +G
Sbjct: 18129 GRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG 18188
Query: 993 DVGVIKCIVKDQ----ETSTMLVVKETIP---EFIRKLQDFE-VK--EKDVAILEVEI-- 1040
D G C ++ T+ L V P E I L FE +K K V VE+
Sbjct: 18189 DEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAA 18248
Query: 1041 ----NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES- 1095
SE + W R+ I + + + + ++ L I + D GEY+ +++S
Sbjct: 18249 ELVQASEPLQIRWLRNKVTIVDSPS-FSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSG 18307
Query: 1096 ---CTAEV-------TVVELPPEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGS 1144
CT ++ +V + P + + + G + + D ++ W K G
Sbjct: 18308 IARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQ 18367
Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-- 1202
++ + +G K L+I + DAG+Y N A +E + T +
Sbjct: 18368 KLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGA 18427
Query: 1203 -PEFILVPANTD------AYLTVEIPDETLDV-TW-YKKKSVIEDTEKFTLISDVKKRTL 1253
P+F P + A L W Y +I+ + +T+ S +L
Sbjct: 18428 KPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSL 18487
Query: 1254 IIRKCTEDDQCEYTCVL 1270
+I + EY C +
Sbjct: 18488 LINSVDKKHFGEYLCTI 18504
Score = 54.4 bits (125), Expect = 8e-07
Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 3/107 (2%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP ++ ++P P ++ EC G+P P+ W++ I P+ + ++ +++ L
Sbjct: 14450 APRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNEGSMSAL 14509
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMT 612
+I E+ ED G + + +N G A S E+ V A + SE+T
Sbjct: 14510 IIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSELT 14556
Score = 54.4 bits (125), Expect = 8e-07
Identities = 99/402 (24%), Positives = 162/402 (40%), Gaps = 36/402 (8%)
Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNR-WIKVADVDRDVETYCIQKLNENCEYMFR 1740
S+ ++W D E+T Y ++ E ++ R W VA + I +L E Y+FR
Sbjct: 15516 SIALKWTSDND----EVT-YTVQMKEANSKRPWAVVAKEISECSA-TIAQLKEGTSYLFR 15569
Query: 1741 VIAQNPVGFSEALE-SEPIVIK--TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG- 1796
VIAQN G + E SE I K T P+ + N IT +E G
Sbjct: 15570 VIAQNKTGQTVTSEQSESIECKDTTESKKPAFTNAPTDLTAVKNGKTKIT---AEFTGHP 15626
Query: 1797 SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
+P I + K+ GK+ I ++ + +++I +N G S+ ++
Sbjct: 15627 APEIHWFKNKKEIFSGKRQWIENIAGATSLTIGEMREDDEGEYKIVVKNTAG-SVEHSC- 15684
Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF-KTVKGKSWT 1913
K+T+ + L ++ + + + T+K S P +I K ++
Sbjct: 15685 -KLTMDQ-LPEINRVDRYASTLVFDKGETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKM 15742
Query: 1914 KIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
KI TV +V I +I +D+ F + +N G + +++ P P
Sbjct: 15743 KIEKTVLNTVLT--INSIDSQDQGEFALKIKNRCGED--KYAIGIQVTDRPAAPGKPA-- 15796
Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF-NIRDL 2031
+E + V S V W P DGG+P+ Y + + W K +V F + +L
Sbjct: 15797 VEDQNVDS--VRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWT---KAEVTKQAFITLFNL 15851
Query: 2032 SENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
+Y R+ A N G SEP SDE V+ S EEP
Sbjct: 15852 VPGESYRFRVRADNTFGQSEP--SDESELVVVKNVSRVVEEP 15891
Score = 54.0 bits (124), Expect = 1e-06
Identities = 51/204 (25%), Positives = 79/204 (38%), Gaps = 20/204 (9%)
Query: 1482 PTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGK---KLKTAKATYENR-XXXX 1536
P V +PL + T TE N ++ L G P P + WY DGK + +T + ++ R
Sbjct: 16830 PVVTRPLADATVTEGNREL-LEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLK 16888
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ---------QKPVITISNEDIKQKHKVG 1587
Y C N G VET +V ++ Q P +D+ K G
Sbjct: 16889 IYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLK-TAG 16947
Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK---EKTSVIRIKELKRSHSSKYT 1644
+ T P +V+W NG L+ K N T+ + T+ + I+ + YT
Sbjct: 16948 ETATFTCQSYANPAAQVVWLHNGKALQQTKS-NYKTRLFDDNTATLVIENVTDELCGTYT 17006
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSK 1668
A+N G L + +K
Sbjct: 17007 AVANNQFGDVHTSAQLTISGSEAK 17030
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/196 (25%), Positives = 87/196 (44%), Gaps = 17/196 (8%)
Query: 631 GIPPTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G + + PK+ V + S+++++C+ + P D W G ++PDE +++ +
Sbjct: 8762 GTGQSIIEHPKSHAVGQMNSEVIIKCK-TSQPISDAKWFCNGMVLLPDEQVNMTVTG--- 8817
Query: 690 MYC-SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
C +VL++ +G Y V+ G S P +L PP ++ L I Q
Sbjct: 8818 --CEAVLRLVKFLPQNKGNYHVLIDGSIG--SQPAIL----SGPVPPVILNKLTKPITHQ 8869
Query: 749 -GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLK 806
G+S +G P P + N +PV + K + + ++ PK K D G YT+
Sbjct: 8870 AGKSFTYKFNFMGAPAPRLRVLSNGEPV-SFDVKYEIYDNIASLYIPKMSKRDGGEYTVV 8928
Query: 807 AENSEGIAETSAVITV 822
EN G E+ IT+
Sbjct: 8929 LENKYGKDESDLHITM 8944
Score = 53.2 bits (122), Expect = 2e-06
Identities = 89/412 (21%), Positives = 155/412 (37%), Gaps = 43/412 (10%)
Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKL 1360
G + L + + W + + I+ + S D KS L V++ D G Y+
Sbjct: 17372 GQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRC 17431
Query: 1361 RLENNCGHADVEMNVTILD--KPSPPGKPNILEIDSSSI---NICWDEPENTGNSTIIYY 1415
+ N G+A+ E NV + D K P L DS++I NI + + + +
Sbjct: 17432 VVTNKYGYAESECNVAVEDVTKFIAPSFSATLS-DSTAILGHNITLECKVEGSPAPEVSW 17490
Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
+ + I TT I + K S Y + ++ T+ + K
Sbjct: 17491 TKDGERISTTRRIRQTQDENGNCKLSISKAESD-DMGVYVCSATSVAGVDSTSSMVMIAK 17549
Query: 1476 ETKIQSPTV---------EKP----LKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGK 1520
T S V EKP E NE + T I V P+P VTW +DG+
Sbjct: 17550 TTGTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGR 17609
Query: 1521 K-LKTAK-----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVI 1573
+ L+T + T + + C A N +G V V +Q+ KP
Sbjct: 17610 EILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPAN 17669
Query: 1574 TISNEDIKQKHKVGDEWLV-------TAVIEGIPPPEVIWY---KNGNKL---ENDKEYN 1620
++N K + D +V + + G P P + W +G+K+ + ++
Sbjct: 17670 QLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWT 17729
Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
K + ++ + + R Y A+N++G ++ + L V + +P GP
Sbjct: 17730 ECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGP 17781
Score = 52.4 bits (120), Expect = 3e-06
Identities = 70/302 (23%), Positives = 124/302 (41%), Gaps = 45/302 (14%)
Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGE 1086
V E ++ VE++ V W +D + + + + + +G+ R + I NT V D+G
Sbjct: 3014 VMEGQPTVITVELDDPNVIVNWLKDRRPLHENERIRLETDGQGNHRVI-IPNTCVGDQGT 3072
Query: 1087 YSCILRDESCTAEVTVVELPPE----IITR--------LQNQKVNKGNKATFEIELTKGD 1134
Y + ES + V E E +I +Q V G+ AT EL + +
Sbjct: 3073 YLALTSSESVAITLVVEERIEEKEVMVIASGTESEEDDVQEYLVPPGSTATIACELEECE 3132
Query: 1135 AL--VRWFKDGSEIQF----SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
+RW +DG +I+F + H+Q +G K L ++D D+G Y E +C
Sbjct: 3133 LKRSIRWLRDGKDIRFEQGKTEHVQ---NGLKHYLVVHDATSLDSGLYKTERSEEQC--- 3186
Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTL--I 1245
E ++P A + + + + W K ++I D +F +
Sbjct: 3187 ---------------EETIIPRGVVATIQCQTSEPQESIQWSKDGNIIPSDISRFEFRSL 3231
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305
+ + ++I + D Y+ VL++ KS+ K+ VVE E E + DV
Sbjct: 3232 DNNQSHEMVISNISWSDAGVYS-VLINGKSSFVSKIVVVESELITQSVEEEPEAEPEIDV 3290
Query: 1306 TL 1307
+L
Sbjct: 3291 SL 3292
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 10/168 (5%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
G+ +SAQV ++ W K+ K + A T + S + V GV+T K +
Sbjct: 15204 GKEGEISAQVA-ETGVSVEWKKDGKALDASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVK 15262
Query: 809 NSEGIAE-TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
+SEG E S +TV+ P E I + VK KL A+++ P S+ W
Sbjct: 15263 SSEGDEEEVSIAVTVKLPEVPKVEAEQSI-----VEVKVGDVAKLSAKISE-PASSVNWT 15316
Query: 868 RNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGK 914
++++ I + + +L I+ DS SG YK N AGK
Sbjct: 15317 KDDKPIKEDGNVKAQLSPDGTAQLTISKTDSA-HSGIYKLNVENDAGK 15363
Score = 49.2 bits (112), Expect = 3e-05
Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
D G ++L C + P + W G EI P N ++ +E+D + L+I N K
Sbjct: 14651 DFGETMVLFCE-TSKPVRKVKWFKNGVEIWPQMNKAI-MENDGKR--ATLEIKNFDKHDI 14706
Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
G YT +E A +V ++ P ++ + + V G + + G P PT
Sbjct: 14707 GAYTASVSEKETSAPAKLVFEVAPNLIIPTEIRD---GVTVHAGNEFDFAVEFSGFPIPT 14763
Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
I N P+KA+ ++ D +K + + G + AE+ G
Sbjct: 14764 IHLTNNGTPLKAIAVVTEYDDSVSVRMKDVTLDNSGTVRVIAESPLG 14810
Score = 49.2 bits (112), Expect = 3e-05
Identities = 22/69 (31%), Positives = 39/69 (56%)
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
A + G P P + W K G KL N+++Y + + ++RI + R+ + KY + A N +G
Sbjct: 18350 AKVIGHPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 18409
Query: 1654 SSVEVTLKV 1662
++ E+ L V
Sbjct: 18410 ANAELELTV 18418
Score = 48.4 bits (110), Expect = 6e-05
Identities = 22/78 (28%), Positives = 43/78 (55%)
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
++G+ + +I G+P PE+ W +G+ + + EY+I ++ ++RI+ +Y
Sbjct: 1691 RIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYC 1750
Query: 1645 IEASNTAGTSSVEVTLKV 1662
ASN AGT+ + LK+
Sbjct: 1751 CTASNVAGTTFSKCYLKL 1768
Score = 48.0 bits (109), Expect = 7e-05
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F +K + G + L+C + +P+P+I W G+ IVP++ S+ E + C
Sbjct: 1679 PKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGV---C- 1734
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
+L+I + EG Y A N G LK+ + + ++ L +
Sbjct: 1735 ILRIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDDAVDLLRQLSEI 1785
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/311 (20%), Positives = 115/311 (36%), Gaps = 24/311 (7%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL---VR 1138
H+E E S ES + + LPP+ I L + N + T V
Sbjct: 923 HEEAEIS-----ESVLTDDVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVS 977
Query: 1139 WFKDGSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCE------VGNSKCTAILT 1190
W KDG +I + ++ DG Q L I D+G Y+C V NS C LT
Sbjct: 978 WQKDGMDIYENEKYEVMQFADGA-QILTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELT 1036
Query: 1191 VEEPSINFTLRLPEFI----LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLIS 1246
+ S + E + D + V + +E +K+ E+ + ++
Sbjct: 1037 ISAESSPESFEKVEITPPEEVKETGIDDDIEVILKEEVSGTAQIEKRE--EEFKLLVKVA 1094
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
D TL+ E ++ ++E + P+ EY +K +
Sbjct: 1095 DQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQ-EPRFETSTDEYHVKENGTIK 1153
Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
+ P P EW + ++ ++ ++ ++++ +K V+ G Y LR N
Sbjct: 1154 MAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCH 1213
Query: 1367 GHADVEMNVTI 1377
G + + M +T+
Sbjct: 1214 GESILPMKLTV 1224
Score = 46.8 bits (106), Expect = 2e-04
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
+ Q P TIS + K DE+ + G P P V WYK ++ D++ ++ T
Sbjct: 17245 VGQAPQFTISPQS-KIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTST 17303
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
+S++ +K + + + IE N G +S + +++KP+
Sbjct: 17304 SSILNLKSQEENGTFNCLIE--NELGQASASCQVTIFNKPA 17342
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 1481 SPTVEKPLKNITTEPNEDIE-LTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXX 1534
+P+V+K L++I + I L+C GVP PKV WY+D K+L Y E
Sbjct: 16267 APSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAE 16326
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
Y C A ND G + T + ++
Sbjct: 16327 LTVKNIVESDAGKYTCRATNDLGSIMTHAKLSVK 16360
Score = 46.0 bits (104), Expect = 3e-04
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
PP FI + V TI LV V +P W+ N + + Q G NI +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVGHGINISRL 148
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
S + G YKCV N AG S+ +T++ ++ +HL S E
Sbjct: 149 KV---SRPEQGVYKCVTRNPAGVSTSYGYITVNADR----EHLSSSKE 189
Score = 45.6 bits (103), Expect = 4e-04
Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F +V E I + + P P + W F E++ +N+S+ E+ S
Sbjct: 1135 PRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGT----S 1190
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG---E 750
+ + NV+K Q G Y + A N GE+ LP+ L + E + + ++V Q E
Sbjct: 1191 AIILKNVQKRQGGNYFLRAHNCHGESILPMKLTVDPIEAVTHVLETSIPKVVVEQDAKEE 1250
Query: 751 SVILSAQVV 759
V +A+++
Sbjct: 1251 EVRRAAEII 1259
Score = 45.6 bits (103), Expect = 4e-04
Identities = 86/421 (20%), Positives = 178/421 (42%), Gaps = 53/421 (12%)
Query: 831 EPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+PP F+ + + + EK T+K V V P+ + W + +++ + +F+
Sbjct: 4037 QPPYFLLPLSDKVVIDEKCTLKCV--VMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIAL 4094
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---------DVEKVTFVKHLQKSYET 940
L + N+ D +C A N GK + +T D++K +FV L+ + T
Sbjct: 4095 LRMKNIKK--DKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTT 4152
Query: 941 EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
+ T L+C V T +G+ I+ + V++C
Sbjct: 4153 TDHAT--LKCIV---VGTPLPDVSCSFNGVTDNSKIRSEDGIVLIQVNDVTEEGIVVECT 4207
Query: 1001 VKDQETST-----MLVVKETIPEFIRKLQDFEV-----KEKDVAILEVEINSETADVVWE 1050
+ ++ S+ + ++K+ + R + F E+++++ I S + W+
Sbjct: 4208 ISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWK 4267
Query: 1051 RDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
+G+ I+ + Y FE I K++ H E++CI ++E T VE+P EI
Sbjct: 4268 HNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSH---EFTCIAKNEYGQ---TTVEIPVEI 4321
Query: 1110 ITRLQNQKV---NKGNKATFE--IEL---TKGDALV--RWFKDGSEIQFSNHIQLTIDGK 1159
+ +N+ + A + ++L +GD + +WF+DG ++ + ++T+D
Sbjct: 4322 GLKTENKLTLVKTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKC 4381
Query: 1160 KQKLKIYDCDLDDAGE--YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
L++ L++ G +CEV NS + ++ T + +F++ N+ +L
Sbjct: 4382 ISTLQL---KLEETGTRIITCEVSNSSSKVNASCNVERVHNT--VSDFVMTNDNSTRFLA 4436
Query: 1218 V 1218
V
Sbjct: 4437 V 4437
Score = 44.8 bits (101), Expect = 7e-04
Identities = 47/213 (22%), Positives = 84/213 (39%), Gaps = 23/213 (10%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP+ I+ +K+ V +++ L +V +P W N K V + H I I +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVG-HGINISR 147
Query: 794 PKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENA-----------------EPPLF 835
K + ++GVY N G++ + ITV E + + P F
Sbjct: 148 LKVSRPEQGVYKCVTRNPAGVSTSYGYITVNADREHLSSSKEDMRLQRQHSVTYHQAPRF 207
Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
+ + + V + + V NP +W+ N + S + F ++ +
Sbjct: 208 LTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMF-SPDVNRSVVRF 266
Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
+ +G+YK VASN G + V D++KV
Sbjct: 267 SIPV-AGEYKVVASNVHGSAMSCGHV--DIQKV 296
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/180 (21%), Positives = 71/180 (39%), Gaps = 9/180 (5%)
Query: 1023 LQDFEVKEKDVAILEVEINS---ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ + VK + A + E+N+ + + W I ++D + L IR+
Sbjct: 2911 IPSYVVKLESTATITCELNNYLPKNCTIDWYCGKTKIIIDHEQFDRISHDLLEVLIIRSV 2970
Query: 1080 SVHDEGEYSCILRDESCTAEVTVVE-----LPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ YS + ++ +VE I+TR + Q V +G +EL +
Sbjct: 2971 EAINGNLYSLKINEDLFPVAYLIVENTNLTTSANILTRPETQFVMEGQPTVITVELDDPN 3030
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGK-KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+V W KD + + I+L DG+ ++ I + + D G Y + L VEE
Sbjct: 3031 VIVNWLKDRRPLHENERIRLETDGQGNHRVIIPNTCVGDQGTYLALTSSESVAITLVVEE 3090
Score = 43.2 bits (97), Expect = 0.002
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVN---EVDISDASE 1466
TI + + +++ + E IS+K N+ N+ + A N +V+ S
Sbjct: 3819 TISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVETSCEIV 3878
Query: 1467 TTEYYKVIKETKIQS---PTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
+ VI ++ I S P PL + +T N+ I + C F G P P W +DG L
Sbjct: 3879 AADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLL 3938
Query: 1523 KTAK---ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
K T + Y C N+ G TSC + +
Sbjct: 3939 DLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDV 3986
Score = 43.2 bits (97), Expect = 0.002
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 9/136 (6%)
Query: 693 SVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
S +KI V G +T + EG E + I + +K E P+V + V+ G+
Sbjct: 15242 STVKIPIVDVNTSGVFTCKVKSSEGDEEEVSIAVTVKL--PEVPKVEAEQSIVEVKVGDV 15299
Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
LSA++ P ++ W K++KP+K S T +TI K G+Y L
Sbjct: 15300 AKLSAKI-SEPASSVNWTKDDKPIKEDGNVKAQLSPDGTAQLTISKTDSA-HSGIYKLNV 15357
Query: 808 ENSEGIAETSAVITVE 823
EN G + + ++
Sbjct: 15358 ENDAGKGKVEIALRIK 15373
Score = 43.2 bits (97), Expect = 0.002
Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 8/189 (4%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
D E P F+ P + + P P+I W +EI + + +
Sbjct: 15592 DTTESKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIA 15651
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
+ L I +++ EG Y +V N G L + E +V +++
Sbjct: 15652 G----ATSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQ-LPEINRVDRYASTLVF 15706
Query: 747 RQGESVILSAQVVGNPRPTITWCKNN-KPVKALPTKSDGDTHSITILKPKKV--KDEGVY 803
+GE+V L G P+P + W NN K ++ T T+L + +D+G +
Sbjct: 15707 DKGETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEF 15766
Query: 804 TLKAENSEG 812
LK +N G
Sbjct: 15767 ALKIKNRCG 15775
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ E + P F H + T++ + G+P P + W+ ++ SQ+ M
Sbjct: 1124 EEDNQIEATQEPRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSM 1183
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
YY + + ++++ V G + A N G + +L V+
Sbjct: 1184 YY-EAGTSAIILKNVQKRQGGNYFLRAHNCHGESILPMKLTVD 1225
Score = 42.3 bits (95), Expect = 0.004
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 1780 DNESVYITW-FPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
+ E+V +TW P+E NG S + +Y VE K +G +W+ A + L T Y F
Sbjct: 10471 ERETVTLTWSLPTELNG-SNVNEYLVERKTVDGGRWRHACTVTDSRAVVDGLFSGTEYVF 10529
Query: 1838 RIYARNEIGTSLP 1850
R+ A N G S P
Sbjct: 10530 RVVAVNGAGQSAP 10542
Score = 42.3 bits (95), Expect = 0.004
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
++G+P P+V WYK+ +L +Y+ E + + +K + S + KYT A+N G+
Sbjct: 16292 VDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATNDLGSI 16351
Query: 1655 SVEVTLKV 1662
L V
Sbjct: 16352 MTHAKLSV 16359
Score = 42.3 bits (95), Expect = 0.004
Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1564 VVG--IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
VVG IQ+ PV+T D G+ L+ ++G P P + WY +G + +
Sbjct: 16821 VVGGEIQRPPVVTRPLADATVTE--GNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRT 16878
Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
+ + ++I E H+ +Y + SN G + V + P E
Sbjct: 16879 YFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETR-AIVVVEAPDAAE 16926
Score = 41.1 bits (92), Expect = 0.008
Identities = 54/256 (21%), Positives = 107/256 (41%), Gaps = 26/256 (10%)
Query: 996 VIKCIVKDQETSTMLVVKETIPE--FIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
V K + +++ T+ VKE + + + K+QD E L+ ++E+ E+
Sbjct: 15082 VKKKVAENKGEETLQEVKEKLKKGKAVEKVQD----ESRRGSLQASSDNESVTTTSEKRS 15137
Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRL 1113
E K ++ EK+ L + + ++ E ++ + + V ++ + + +
Sbjct: 15138 EAELEKNSEKSAEKKSTSADLEAADKAETEKSETG---KETTEKKKKVVKKVAKKGLVKA 15194
Query: 1114 QNQKVN--KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
K+ G + ++ + V W KDG + S +T G +KI D++
Sbjct: 15195 DKSKIELTAGKEGEISAQVAETGVSVEWKKDGKALDAS--YTVTSTGGVSTVKIPIVDVN 15252
Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD---------AYLTVEIPD 1222
+G ++C+V +S+ EE SI T++LPE V A A L+ +I +
Sbjct: 15253 TSGVFTCKVKSSEGDE----EEVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISE 15308
Query: 1223 ETLDVTWYKKKSVIED 1238
V W K I++
Sbjct: 15309 PASSVNWTKDDKPIKE 15324
Score = 41.1 bits (92), Expect = 0.008
Identities = 51/220 (23%), Positives = 86/220 (39%), Gaps = 15/220 (6%)
Query: 894 NVDSEIDSGDYKCVASNSAGKSS--HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
+ +++++ D + GK + +V V K VK + E GK + Q
Sbjct: 15153 STSADLEAADKAETEKSETGKETTEKKKKVVKKVAKKGLVKADKSKIELTAGKEGEISAQ 15212
Query: 952 TSHT-VSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVK-----DQ 1004
+ T VS +W KK+ +D + G GV C VK ++
Sbjct: 15213 VAETGVSVEW---KKDGKALDASYTVTSTGGVSTVKIPIVDVNTSGVFTCKVKSSEGDEE 15269
Query: 1005 ETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN-K 1062
E S + VK +P+ + EVK DVA L +I+ + V W +D + IK N K
Sbjct: 15270 EVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISEPASSVNWTKDDKPIKEDGNVK 15329
Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
G + + S H G Y + +++ +V +
Sbjct: 15330 AQLSPDGTAQLTISKTDSAH-SGIYKLNVENDAGKGKVEI 15368
Score = 40.7 bits (91), Expect = 0.011
Identities = 68/301 (22%), Positives = 120/301 (39%), Gaps = 29/301 (9%)
Query: 117 GSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQN 176
G +K E + K+ E+ T + D ++E ESK V + P+
Sbjct: 13359 GKLKIEEESAAKSKQTVEEQAKLDAQTKAKTAEKQTKLEKDEKSTKESESKETVDEKPKK 13418
Query: 177 IIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIE 236
+ + K+ E+S+ I++ SE V E P + ET + + K+ K T K +
Sbjct: 13419 KVLKKKT-----EKSDSSISQKSETSKTVVESAG-PSESETQKVADAARKQ-KETDEK-Q 13470
Query: 237 RKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPES 296
+ E E++ + A+ E K K + ++K T S
Sbjct: 13471 KLEAEITAKKSADE------KSKLEAESKLKKAAEVEAAKKQK-EKDEQLKLDTE--AAS 13521
Query: 297 IKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKL--------PDVEKTELEQPLFSY 348
K + KQ+ I +A K +K++ +L D EK +LE+
Sbjct: 13522 KKAAAEKLELEKQSHIKKAAEVDAVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKA 13581
Query: 349 EDI--VESKKDENEIIQEKQTLEELPKEDVPEQ--YTITPRKSSAQKIDEIVDEVTIKKR 404
+I +E +K++ ++ QE+ LE+ K+ +Q + T K + + E VDE KK
Sbjct: 13582 AEIALIEIQKEQEKLAQEQSRLEDEAKKSAEKQKLESETKSKQTEEAPKESVDEKPKKKV 13641
Query: 405 L 405
L
Sbjct: 13642 L 13642
Score = 40.7 bits (91), Expect = 0.011
Identities = 40/208 (19%), Positives = 79/208 (37%), Gaps = 14/208 (6%)
Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--- 1529
VI+E P L++ + E L +P+P V WY +G+ + + Y
Sbjct: 16389 VIEEMIDMPPNFHHLLQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRK 16448
Query: 1530 --ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVITISNEDIKQ 1582
+ R +K + N GE E+ + + Q P D+K
Sbjct: 16449 HDKGRYELHILSVDSTDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKC 16508
Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHS 1640
D + I+ P PE+ W++N +++E+ + + + + + + I + S
Sbjct: 16509 SES--DILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDS 16566
Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
+Y A N G + +++ + SK
Sbjct: 16567 GEYKCVAKNKIGKAHTVCCVRIEELLSK 16594
Score = 39.1 bits (87), Expect = 0.034
Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 10/198 (5%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRX-XX 1535
Q+P + L N E ++L C+ G+PQP++ W DG + YE+
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
Y C A N G + C + + + + + K+ D L T
Sbjct: 1737 RIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDDAVDLLRQLSEIKIIDPTLSTGY 1796
Query: 1596 -IEGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTAG 1652
+ I E ++ N L DKE IT + R + +R S++ T++ +
Sbjct: 1797 PMSMISDEENTSHQLLSNVLLTDKEVPITATYNEDLSRAESFRRFFESAETTVKVTELYQ 1856
Query: 1653 TSSVEVTLKVYDKPSKPE 1670
SVE + +P K E
Sbjct: 1857 GESVEAQ---FQQPEKRE 1871
Score = 39.1 bits (87), Expect = 0.034
Identities = 43/225 (19%), Positives = 86/225 (38%), Gaps = 22/225 (9%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWF 1140
+DE E S I D + + + P RL + +K T E+ + + W
Sbjct: 3765 YDEDECSTIA-DTITSLSSSPLYTAPVFTERLPSSACFANSKLTLEVMFSGVPQPTISWL 3823
Query: 1141 KDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILT--- 1190
D E + I + + ++ ++ D + G C N + C +
Sbjct: 3824 IDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEI 3883
Query: 1191 --VEEPSI------NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF 1242
+ + SI +F + LPE + N + + + L ++K V+ D +K+
Sbjct: 3884 SVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKY 3943
Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK--STTKLKVEVVE 1285
+ ++ L I + DD+ YTC + + +T ++VV+
Sbjct: 3944 QVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDVVD 3988
Score = 39.1 bits (87), Expect = 0.034
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 523 DGSTVQFECQVEGYPRPQITWF---RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
+G T + +V+G+P P++ W ++ ++ PS +Q+ Y D I ED
Sbjct: 12297 EGETAKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCTFEDDD 12356
Query: 580 TFTCVAKNAAGFASSTTELIVE 601
++ + +N AG S ++ V+
Sbjct: 12357 DYSLLVENLAGVDSCNFQVFVD 12378
Score = 38.7 bits (86), Expect = 0.045
Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
+ P+ + L + R GE V L + G P+P I W + P+ S + IL
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 793 KPKK--VKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
+ + ++DEG Y A N G + + + E ++
Sbjct: 1737 RIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDD 1774
Score = 38.3 bits (85), Expect = 0.059
Identities = 38/174 (21%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798
++ V +G+ +++ ++ +P + W K+ +P+ + + ++DG + I+ V
Sbjct: 3010 ETQFVMEGQPTVITVEL-DDPNVIVNWLKDRRPLHENERIRLETDGQGNHRVIIPNTCVG 3068
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR------FQEITVKEKGTIKL 852
D+G Y L +SE +A T + VEE EE + QE V T +
Sbjct: 3069 DQGTY-LALTSSESVAIT---LVVEERIEEKEVMVIASGTESEEDDVQEYLVPPGSTATI 3124
Query: 853 VARVTRNPVP-SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
+ + SI W R+ + I + T++ ++ + + +DSG YK
Sbjct: 3125 ACELEECELKRSIRWLRDGKDIRFEQGKTEHVQNGLKHYLVVHDATSLDSGLYK 3178
Score = 37.9 bits (84), Expect = 0.078
Identities = 20/71 (28%), Positives = 34/71 (47%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+ A I G P P + WY KL+ + ++ + TS I +K +++ Y + A N
Sbjct: 1154 MAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCH 1213
Query: 1652 GTSSVEVTLKV 1662
G S + + L V
Sbjct: 1214 GESILPMKLTV 1224
Score = 37.5 bits (83), Expect = 0.10
Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD---ENISVAIESDM 688
IPP F K EG ++++ + PEP + + ++ +++ D + + V E +M
Sbjct: 12438 IPPRFDKILSDHDAIEGENVVMMVETLGEPEPQVRF-YRDGKLIDDGSGDRMEVRHEDEM 12496
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
+ +LK ++ K +E Y A+N GEA
Sbjct: 12497 RKHWLILK--DICKDEEAEYACQAINVAGEA 12525
Score = 37.1 bits (82), Expect = 0.14
Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 19/217 (8%)
Query: 1187 AILTVEEPSINFTLRL---PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
A L VE ++ + + PE V +TVE+ D + V W K + + + E+
Sbjct: 2990 AYLIVENTNLTTSANILTRPETQFVMEGQPTVITVELDDPNVIVNWLKDRRPLHENERIR 3049
Query: 1244 LISDVK--KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV---------D 1292
L +D + R +I C D ++ + T + E +E +V D
Sbjct: 3050 LETDGQGNHRVIIPNTCVGDQGTYLALTSSESVAITLVVEERIEEKEVMVIASGTESEED 3109
Query: 1293 YEREYRIKRGSDVTLLVDYQAFP-QPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKV 1350
+EY + GS T+ + + + + W+ + K I+ + T+ + L +
Sbjct: 3110 DVQEYLVPPGSTATIACELEECELKRSIRWLRDGKDIRFEQGKTEHVQNGLKHYLVVHDA 3169
Query: 1351 ENTDAGIYKL-RLENNCGHADVEMNV--TILDKPSPP 1384
+ D+G+YK R E C + V TI + S P
Sbjct: 3170 TSLDSGLYKTERSEEQCEETIIPRGVVATIQCQTSEP 3206
Score = 37.1 bits (82), Expect = 0.14
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Query: 322 KVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDE--NEIIQEKQTLEELPKE--DVP 377
K +K+ +PP +K E+ S E ++ESKK E I E+Q ++ E VP
Sbjct: 12786 KSRKKEGLPPAKKSEKKDEVTAEKQSTEALIESKKKEVDESKISEQQPSDKNKSEVVGVP 12845
Query: 378 EQYTITPRKSSAQKIDEIVDEVTIKKR 404
E+ K +I+E+ + TIKK+
Sbjct: 12846 EKAAGPETKKDVSEIEEVPKKKTIKKK 12872
Score = 36.7 bits (81), Expect = 0.18
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 3/114 (2%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
EPP+ + L S+I V E ++LS V P W N VK + D H+ +
Sbjct: 404 EPPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKKSQSVVLLDEHNKST 463
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA--EPPLFINRFQEIT 843
L +G Y + A N G + +T ++ A EPP + +T
Sbjct: 464 LVLHPPVKQGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVT 517
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 806 KAENSEGIA-ETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +N +GI E ++ TE +A P P F+ + + ++L + P P
Sbjct: 1649 EGDNRQGIEDEPFTEVSQSLATESSAAPQAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQP 1708
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
I W + + I P++ + ++ L I + E D G+Y C ASN AG
Sbjct: 1709 EIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIE-DEGEYCCTASNVAG 1758
Score = 36.7 bits (81), Expect = 0.18
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKAL--PTKSDGDTHSITILKPK----KVKD 799
V++GE+ L+ +V G P P + W KN K + + TK D HS + + +D
Sbjct: 12295 VKEGETAKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCTFED 12354
Query: 800 EGVYTLKAENSEGIAETSAVITVE 823
+ Y+L EN G+ + + V+
Sbjct: 12355 DDDYSLLVENLAGVDSCNFQVFVD 12378
Score = 36.7 bits (81), Expect = 0.18
Identities = 25/121 (20%), Positives = 54/121 (44%), Gaps = 5/121 (4%)
Query: 485 QKKLNEKIDKLPVFEKPTSEE--QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQIT 542
+K+ +I ++ P + Q + P F + L +G V + G P PQ+
Sbjct: 12413 KKRKKRRIKRVVERRNPNAPRLTQLIPPRFDKILSDHDAIEGENVVMMVETLGEPEPQVR 12472
Query: 543 WFRQTAIIKPSQDFQM---YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
++R +I +M + D+ L+++++ ++ + C A N AG A ++++
Sbjct: 12473 FYRDGKLIDDGSGDRMEVRHEDEMRKHWLILKDICKDEEAEYACQAINVAGEAWCFSDVV 12532
Query: 600 V 600
V
Sbjct: 12533 V 12533
Score = 36.3 bits (80), Expect = 0.24
Identities = 44/194 (22%), Positives = 79/194 (40%), Gaps = 22/194 (11%)
Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
+E L C+ G+P V W DG + + +E+ +C A
Sbjct: 4052 DEKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALLRMKNIKKDKSVVQCEA 4111
Query: 1553 FNDHGEVETSCVV---GIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
N G+V TSCV+ G++ QKP +S +K D + ++ G P P
Sbjct: 4112 INCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLS---LKDTCTTTDHATLKCIVVGTPLP 4168
Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+V NG +N K I +++ +I++ ++ SN G+S+ +K+
Sbjct: 4169 DVSCSFNG-VTDNSK---IRSEDGIVLIQVNDV-TEEGIVVECTISNETGSSTSNCVVKI 4223
Query: 1663 YDKPSKP-EGPVIM 1675
+ K + P+I+
Sbjct: 4224 IKQEEKNYQRPIIV 4237
Score = 36.3 bits (80), Expect = 0.24
Identities = 43/209 (20%), Positives = 83/209 (39%), Gaps = 9/209 (4%)
Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
T + E++ D + + G SH + ++ V FVK+L + +EG+ V +
Sbjct: 13929 TLIIDEVEPTDSGMEITATCGTESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTL 13988
Query: 953 SHTVSTK---WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM 1009
+H + W + K + I G D G K + + ST
Sbjct: 13989 NHPIDISKVVWLKDGKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGVDCSTH 14048
Query: 1010 LVVK-ETIPEFIRKLQDFEVKEKD--VAILEVEINSETADVVWERDGEIIK-PKKNKYDF 1065
L ++ + + + + + + +KD ++L ++ A DG+ ++ +++ D
Sbjct: 14049 LSIQGKPVLKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDV 14108
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
G KL R S D GEY L++E
Sbjct: 14109 VDDG--LKLTKRGVSKTDAGEYEVKLKNE 14135
Score = 35.9 bits (79), Expect = 0.32
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 3/137 (2%)
Query: 1287 PPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
PPK V + + L VD QA P W VN +KK + +D + S
Sbjct: 405 PPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKK-SQSVVLLDEHNKS- 462
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
T+ G YK+ N+ G V VT + + +I S++ + E
Sbjct: 463 TLVLHPPVKQGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVTCSHEE 522
Query: 1406 NTGNSTIIYYVVEYQEI 1422
+ G+ + + V QE+
Sbjct: 523 DVGSHSSLQTVRRIQEM 539
Score = 35.9 bits (79), Expect = 0.32
Identities = 44/170 (25%), Positives = 73/170 (42%), Gaps = 21/170 (12%)
Query: 1612 KLENDKEYNITTKEK---TSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKP 1666
K EN+ E+ E+ T ++ L ++ IEA N AG ++S V+ K+ +
Sbjct: 14289 KRENEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVSKKLTVEG 14348
Query: 1667 SKPE---GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV---- 1719
PE +++ + + V + WK DG E + ++ ++ W V D+
Sbjct: 14349 LVPEIILDMPMVKVLDNDKVEVTWK---SDGEKE---FVVQYKSDGSSIWASV-DIGGPR 14401
Query: 1720 -DRDVETYCI-QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
+ + CI L E Y+FRV A+N G E E V+ A D P
Sbjct: 14402 SESAATSKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVVVLADDAP 14451
Score = 35.5 bits (78), Expect = 0.42
Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Query: 1091 LRDESCTAEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSE 1145
+RD+ + E+ LP P+I+ L + G + ++T A V W KD
Sbjct: 801 IRDDDSSFEIVPPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVN 860
Query: 1146 IQ---FSNHIQLTI-DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
++ + + T+ DG +L +C +DAG Y C N TA
Sbjct: 861 VEDWVLNKDVTTTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTA 906
Score = 35.5 bits (78), Expect = 0.42
Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 510 PIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P+ + KL +P G + ++ G P P++ + +++Y DN+A+L
Sbjct: 8856 PVILNKLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIY---DNIASL 8912
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEM 611
I ++ D G +T V +N G S + +V+ PL +++
Sbjct: 8913 YIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKPRKAQL 8956
Score = 35.5 bits (78), Expect = 0.42
Identities = 37/182 (20%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-----XYKC 1550
NE + + C P + W R+ +L Y Y C
Sbjct: 18136 NESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYAC 18195
Query: 1551 IAFNDHGEVETSC---VVGIQQKPVITISN----EDIKQKHKVGDEW---LVTAVIEGIP 1600
A N+ G T+ V G+ I E IK KV D L +++
Sbjct: 18196 EAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 18255
Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
P ++ W +N + + ++ + E + I ++ +YT+EA N +G + + L
Sbjct: 18256 PLQIRWLRNKVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQL 18315
Query: 1661 KV 1662
V
Sbjct: 18316 DV 18317
Score = 35.1 bits (77), Expect = 0.55
Identities = 22/96 (22%), Positives = 38/96 (39%), Gaps = 1/96 (1%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+S P F + + G+P P+I WF+ I + Q +
Sbjct: 15595 ESKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKR-QWIENIAGA 15653
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
+L I E+ +D G + V KN AG + +L ++
Sbjct: 15654 TSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMD 15689
Score = 34.7 bits (76), Expect = 0.73
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 5/91 (5%)
Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLEN 1364
TL D P P +W + K + S ++ A LT+K + +DAG Y R N
Sbjct: 16287 TLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRATN 16346
Query: 1365 NCG----HADVEMNVTILDKPSPPGKPNILE 1391
+ G HA + + K P ++E
Sbjct: 16347 DLGSIMTHAKLSVKADEKKKKKSKTSPAVIE 16377
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PPK + + YR+ ++L+V+ + P EW N K + + + +++
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQV--GHGINIS 146
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
KV + G+YK N G
Sbjct: 147 RLKVSRPEQGVYKCVTRNPAG 167
Score = 33.9 bits (74), Expect = 1.3
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 633 PPTF-SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP F + P V+ ++L + AIP + AW G E+ +++ + D H
Sbjct: 405 PPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKKSQSV---VLLDEHNK 461
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGE-KEPPQVIEPLKSMIV 746
+++ VK +G Y V A N G S+ + ++K G EPP ++E ++
Sbjct: 462 STLVLHPPVK---QGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVTC 518
Query: 747 RQGESV 752
E V
Sbjct: 519 SHEEDV 524
Score = 33.9 bits (74), Expect = 1.3
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1017 PEFIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P+F+RKL + F + V + + ++ W DG+ I P ++Y + L
Sbjct: 1679 PKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPN-DEYSIVYEDGVCILR 1737
Query: 1076 IRNTSVHDEGEYSC 1089
I +T + DEGEY C
Sbjct: 1738 IESTLIEDEGEYCC 1751
Score = 33.1 bits (72), Expect = 2.2
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 11/135 (8%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
+ A + + P V W K+G + EN+K + + ++ I+ S YT A +
Sbjct: 964 MVATVRSVAPITVSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESE 1023
Query: 1651 AGTSS----VEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGLELTKYA-I 1703
G S+ VE+T+ P E I E+ + + + L + E++ A I
Sbjct: 1024 HGVSNSSCQVELTISAESSPESFEKVEITPPEEVKETGIDDDIEVILKE---EVSGTAQI 1080
Query: 1704 EKHEPDNNRWIKVAD 1718
EK E + +KVAD
Sbjct: 1081 EKREEEFKLLVKVAD 1095
Score = 33.1 bits (72), Expect = 2.2
Identities = 12/30 (40%), Positives = 20/30 (66%)
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
K G+ +T ++G P PE+IW KNG +++
Sbjct: 12296 KEGETAKLTGRVDGFPLPELIWIKNGKEID 12325
Score = 32.3 bits (70), Expect = 3.9
Identities = 42/190 (22%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 1345 LTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
LTI+ N D+G+Y E+ G ++ ++ +TI + SP + EI +
Sbjct: 1003 LTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELTISAESSPESFEKV-EITPP------E 1055
Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWIS-----VKNITKTQTSIQN-LKTNSSYRFRAYAV 1456
E + TG I +++ +E+ T I K + K + + L N AV
Sbjct: 1056 EVKETGIDDDIEVILK-EEVSGTAQIEKREEEFKLLVKVADQVASTLVANVFLEAVHEAV 1114
Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
++ ++ E + +E + ++ T E +K N I++ G P P + WY
Sbjct: 1115 KKIVETEDEEEDNQIEATQEPRFETSTDEYHVKE-----NGTIKMAATISGHPTPFLEWY 1169
Query: 1517 RDGKKLKTAK 1526
+KL+ ++
Sbjct: 1170 FGEEKLQVSQ 1179
Score = 32.3 bits (70), Expect = 3.9
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 9/101 (8%)
Query: 149 ERVTLEKSDLFDSQEDESKPDV-SQPPQNII--EEAKSEPKLIEESEQPIAKTSEIDNEV 205
E V E++ +QED K S+P Q + E A SEP ++ + A + I EV
Sbjct: 3565 EDVPKEEAPSEPTQEDVPKEAAPSEPTQENVPKEAAPSEPT--KDVPKEAAPSEPIQEEV 3622
Query: 206 PEKINVPDDKETSQTPTSFNKRSK-LTPIKIERKEMEVSTP 245
P++ + E +Q + +KRS+ + P +I++ E TP
Sbjct: 3623 PKEATL---SEPTQEQSEVSKRSEPVEPTQIQQAASEEETP 3660
Score = 31.5 bits (68), Expect = 6.8
Identities = 29/135 (21%), Positives = 52/135 (38%), Gaps = 6/135 (4%)
Query: 782 SDGDTHSIT--ILKPKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR 838
SDGDT + + PKK + DE V + + EN E ++ T + I
Sbjct: 8713 SDGDTQEVEQKVTLPKKHQSDEDVISKEEENLETSVSYGSIEETVSFTIGTGQS--IIEH 8770
Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
+ V + + ++ T P+ W+ N ++ P E + G L + +
Sbjct: 8771 PKSHAVGQMNSEVIIKCKTSQPISDAKWFCNGMVLLPDEQVNMTVTGCEAVLRLVKFLPQ 8830
Query: 899 IDSGDYKCVASNSAG 913
+ G+Y + S G
Sbjct: 8831 -NKGNYHVLIDGSIG 8844
Score = 31.5 bits (68), Expect = 6.8
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G TV+ G P+P++ W +I+ S+ ++ N L I + +D G F
Sbjct: 15709 GETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLN-TVLTINSIDSQDQGEFA 15767
Query: 583 CVAKNAAG 590
KN G
Sbjct: 15768 LKIKNRCG 15775
Score = 31.5 bits (68), Expect = 6.8
Identities = 20/87 (22%), Positives = 32/87 (36%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
I G P P+V W K G LE +Y+I + + + Y A+N G +
Sbjct: 18032 ISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIIT 18091
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES 1682
+ V V R+ +E+
Sbjct: 18092 CTSEIDVLPNKEDSAAQVAKRKSRKEA 18118
Score = 31.1 bits (67), Expect = 9.0
Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS-QDFQMYYDDDNVAT 567
AP F+ ++ GS V + +V+ P + +WF + S +M+ D N +
Sbjct: 204 APRFLTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMFSPDVNRS- 262
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
V+R P AG + VA N G A S + ++ + S +T
Sbjct: 263 -VVRFSIPV-AGEYKVVASNVHGSAMSCGHVDIQKVIELEESTLT 305
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/81 (19%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
S +TL V + PQP W+++ +++ + ++ +++ V+ G K R
Sbjct: 3804 SKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCR 3863
Query: 1362 LENNCGHADVEMNVTILDKPS 1382
N G + + D+ S
Sbjct: 3864 ATNCAGQVETSCEIVAADEIS 3884
Score = 31.1 bits (67), Expect = 9.0
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 1014 ETIPEFIRKLQDFEVKEKD-VAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
+ P ++L+D D +A L +++ + V W +D + + KYD +
Sbjct: 16265 DAAPSVKKQLEDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGL 16324
Query: 1072 RKLYIRNTSVHDEGEYSC 1089
+L ++N D G+Y+C
Sbjct: 16325 AELTVKNIVESDAGKYTC 16342
>U55364-6|AAA97973.1| 2541|Caenorhabditis elegans Hypothetical protein
F21C10.7 protein.
Length = 2541
Score = 133 bits (321), Expect = 2e-30
Identities = 138/487 (28%), Positives = 222/487 (45%), Gaps = 62/487 (12%)
Query: 360 EIIQEKQTLEELPKEDVPEQYTITPR-KSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVR 418
+ I+E +T+E E Q T+TP K Q + +IV+E+ + + EI V+ +
Sbjct: 985 QTIEETKTIELTSLEQT--QITLTPEEKQELQILKKIVEEIQMWQE-ETIEIIQL-VD-K 1039
Query: 419 CGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDEN 478
TV + + + +E V + + D S +K T K Q M +
Sbjct: 1040 TPKTVQESETKIKKVNEIQQTVVAQTRRLEDASR-----FRKDETFTK---TVQETMTKQ 1091
Query: 479 NYTQYLQKKLNEKIDKLPVFEKPTSEEQS--MAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
Q L K+L+E+ + + EE+S AP + +L+ +G +F ++ G
Sbjct: 1092 QQVQQLVKELHERAASQNIVVRKQEEERSRVQAPQIITQLKDDVVDEGCRYEFSARINGE 1151
Query: 537 PRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTT 596
P P I+W + +K + D++ Y + VATLVI E F ED +T A N G ASS+
Sbjct: 1152 PEPTISWLKDGIDVKSNMDYRQEYVN-GVATLVIEESFIEDTAEYTVKATNTGGTASSSA 1210
Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
LIV++ S M+ + ILE P F K+ ++ V+EG L+C
Sbjct: 1211 SLIVKSR-----SAMS-------------SAILEEDKPRFVKQMQSVQVNEGETARLDCV 1252
Query: 657 LVAIPEPDIAWLFKGEEIVPD-ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
+V PEP+I W FK E V + E + + D +C ++ I G YTV A N
Sbjct: 1253 VVGKPEPEITW-FKEETAVKESERVHLTFSGD---HCQMI-IDKTVPLDTGIYTVRAKNV 1307
Query: 716 EGEASLPIVLKIKTGEKEPPQ-------------VIEP-LKSMIVRQGESVILSAQVVGN 761
GE + L++ ++ PPQ VI+P L + ++GE+ L G
Sbjct: 1308 HGEVANFCQLRVVPKKQPPPQTPPKPRTPIQRPPVIQPALTNTTWQEGETATLQVFSYGE 1367
Query: 762 PRPTITWCKNNKPVKA-----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
P+P + W N+ PV+ + + DG + +TI + V + G+YT+ AEN G A T
Sbjct: 1368 PKPRVHWKFNDSPVQTSSQVQISEQEDGWSR-LTIQQISPV-NAGMYTVVAENEIGEAVT 1425
Query: 817 SAVITVE 823
A + V+
Sbjct: 1426 GATVHVQ 1432
Score = 94.7 bits (225), Expect = 6e-19
Identities = 62/234 (26%), Positives = 115/234 (49%), Gaps = 11/234 (4%)
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEPLKSMIVRQGESVILSAQVVG 760
Q+ +V E AS IV++ + E+ + PQ+I LK +V +G SA++ G
Sbjct: 1091 QQQVQQLVKELHERAASQNIVVRKQEEERSRVQAPQIITQLKDDVVDEGCRYEFSARING 1150
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENSEGIAETSA 818
P PTI+W K+ VK+ + + +++ ++D YT+KA N+ G A +SA
Sbjct: 1151 EPEPTISWLKDGIDVKSNMDYRQEYVNGVATLVIEESFIEDTAEYTVKATNTGGTASSSA 1210
Query: 819 VITVEEPTEENA-----EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
+ V+ + ++ + P F+ + Q + V E T +L V P P ITW++ +
Sbjct: 1211 SLIVKSRSAMSSAILEEDKPRFVKQMQSVQVNEGETARLDCVVVGKPEPEITWFKEETAV 1270
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
SE + F G++ +++I +D+G Y A N G+ ++ ++ + +K
Sbjct: 1271 KESERVHLTFSGDHCQMIIDKT-VPLDTGIYTVRAKNVHGEVANFCQLRVVPKK 1323
Score = 89.4 bits (212), Expect = 2e-17
Identities = 93/340 (27%), Positives = 146/340 (42%), Gaps = 34/340 (10%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P + K VDEG R+ PEP I+WL G ++ N+ E +
Sbjct: 1125 PQIITQLKDDVVDEGCRYEFSARINGEPEPTISWLKDGIDV--KSNMDYRQEYVNGVATL 1182
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG--------EKEPPQVIEPLKSMI 745
V++ + ++ E YTV A N G AS L +K+ E++ P+ ++ ++S+
Sbjct: 1183 VIEESFIEDTAE--YTVKATNTGGTASSSASLIVKSRSAMSSAILEEDKPRFVKQMQSVQ 1240
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGV 802
V +GE+ L VVG P P ITW K VK + GD H I+ D G+
Sbjct: 1241 VNEGETARLDCVVVGKPEPEITWFKEETAVKESERVHLTFSGD-HCQMIIDKTVPLDTGI 1299
Query: 803 YTLKAENSEG-IAE--TSAVITVEEPTEEN--------AEPPLFINRFQEITVKEKGTIK 851
YT++A+N G +A V+ ++P + PP+ T +E T
Sbjct: 1300 YTVRAKNVHGEVANFCQLRVVPKKQPPPQTPPKPRTPIQRPPVIQPALTNTTWQEGETAT 1359
Query: 852 LVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
L P P + W N+ + S I++ DG + L I + S +++G Y VA
Sbjct: 1360 LQVFSYGEPKPRVHWKFNDSPVQTSSQVQISEQEDGWS-RLTIQQI-SPVNAGMYTVVAE 1417
Query: 910 NSAGKSSHGARVTID---VEKVTFVKHLQKSYETEEGKTV 946
N G++ GA V + VT HLQ+ + G+ V
Sbjct: 1418 NEIGEAVTGATVHVQPSLKRVVTTEHHLQEDMNEQIGQPV 1457
Score = 85.0 bits (201), Expect = 5e-16
Identities = 62/202 (30%), Positives = 95/202 (47%), Gaps = 13/202 (6%)
Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSD 783
K KTG PP + L S +V QGE+ V G P P + W + +P+ K + +
Sbjct: 2305 KKKTGH--PPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGRPLDLKDIRVSNI 2362
Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
G S+ + ++ G Y A+N G+A +SA + V T P FI R
Sbjct: 2363 GGRVSLNF-QNCQLSHVGKYMCTAKNDSGVATSSAQLVVRPKTIA----PDFIQRLISEE 2417
Query: 844 VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDS 901
++E +K RVT +P+P + W R+ I E I + DG + LVI V+ DS
Sbjct: 2418 IEEGSQLKWTVRVTGDPMPKVIWMRDGFEIPDCEEVRIVDHGDGYH-SLVIVKVEGA-DS 2475
Query: 902 GDYKCVASNSAGKSSHGARVTI 923
G + C+A N AG++ A + +
Sbjct: 2476 GQFTCLAENIAGEARSTADLVV 2497
Score = 66.1 bits (154), Expect = 3e-10
Identities = 32/95 (33%), Positives = 57/95 (60%)
Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
+++AP F+++L + +GS +++ +V G P P++ W R I ++ ++ D
Sbjct: 2403 KTIAPDFIQRLISEEIEEGSQLKWTVRVTGDPMPKVIWMRDGFEIPDCEEVRIVDHGDGY 2462
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+LVI +V D+G FTC+A+N AG A ST +L+V
Sbjct: 2463 HSLVIVKVEGADSGQFTCLAENIAGEARSTADLVV 2497
Score = 60.9 bits (141), Expect = 1e-08
Identities = 85/379 (22%), Positives = 161/379 (42%), Gaps = 32/379 (8%)
Query: 833 PLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIEL 890
P FI F+ E TV+E G I + + NP P+ ++ NN ++ SE + + +
Sbjct: 2131 PEFIKAFEREYTVEEGGRIAIECILVGNPKPAARFFFNNKQVTEKSEFLKICHVNDTYSI 2190
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
+I+ E +G YK +A N G + + + V + K+ QK E ++
Sbjct: 2191 IISPAKLE-HAGYYKMIAENKRGVTE--SLTVLHVRPRSLQKYQQKKQEETR-----MQQ 2242
Query: 951 QTSHTVSTKWYHNKKEISGMDH--REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST 1008
Q + T++ ++E + ++ R ++ ++ K + ET
Sbjct: 2243 QARNAGPTEYTTVEEEFAMFEYEQRRPLKHEASKLSTPPPAKRIELEHRK-DEEHLETYD 2301
Query: 1009 MLVVKET--IPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDF 1065
+ K+T P F + L V + + E + A +V W DG + K +
Sbjct: 2302 LEGKKKTGHPPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGRPLDLKDIR--V 2359
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDES--CTAEVTVVELP----PEIITRLQNQKVN 1119
G L +N + G+Y C +++S T+ +V P P+ I RL ++++
Sbjct: 2360 SNIGGRVSLNFQNCQLSHVGKYMCTAKNDSGVATSSAQLVVRPKTIAPDFIQRLISEEIE 2419
Query: 1120 KGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK-KQKLKIYDCDLDDAGEY 1176
+G++ + + +T GD + V W +DG EI +++ G L I + D+G++
Sbjct: 2420 EGSQLKWTVRVT-GDPMPKVIWMRDGFEIPDCEEVRIVDHGDGYHSLVIVKVEGADSGQF 2478
Query: 1177 SC----EVGNSKCTAILTV 1191
+C G ++ TA L V
Sbjct: 2479 TCLAENIAGEARSTADLVV 2497
Score = 59.7 bits (138), Expect = 2e-08
Identities = 89/403 (22%), Positives = 161/403 (39%), Gaps = 25/403 (6%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASL 1345
P I +EREY ++ G + + P+P + N+K + +K + K + + S+
Sbjct: 2131 PEFIKAFEREYTVEEGGRIAIECILVGNPKPAARFFFNNKQVTEKSEFLKICHVNDTYSI 2190
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSPPGKPNILEIDSSSINICWDEP 1404
I + AG YK+ EN G V ++T+L +P K + + + + +
Sbjct: 2191 IISPAKLEHAGYYKMIAENKRG---VTESLTVLHVRPRSLQKYQQKKQEETRMQ---QQA 2244
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
N G + Y VE +E E+ + + K + S L T + R E++
Sbjct: 2245 RNAGPTE--YTTVE-EEFAMFEYEQRRPL-KHEAS--KLSTPPPAK-RI----ELEHRKD 2293
Query: 1465 SETTEYYKVIKETKI-QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
E E Y + + K P + L + E I G P P V W DG+ L
Sbjct: 2294 EEHLETYDLEGKKKTGHPPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGRPLD 2353
Query: 1524 TAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNED 1579
N R Y C A ND G +S + ++ K +
Sbjct: 2354 LKDIRVSNIGGRVSLNFQNCQLSHVGKYMCTAKNDSGVATSSAQLVVRPKTIAPDFIQRL 2413
Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKELKRS 1638
I ++ + G + T + G P P+VIW ++G ++ + +E I + + I +++ +
Sbjct: 2414 ISEEIEEGSQLKWTVRVTGDPMPKVIWMRDGFEIPDCEEVRIVDHGDGYHSLVIVKVEGA 2473
Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
S ++T A N AG + L V + + P + ++++E
Sbjct: 2474 DSGQFTCLAENIAGEARSTADLVVRPQGTAPGNYFHVTKVTQE 2516
Score = 53.6 bits (123), Expect = 1e-06
Identities = 69/340 (20%), Positives = 138/340 (40%), Gaps = 33/340 (9%)
Query: 1456 VNEVDISDASETTEYYKVIKE-TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
V E+ AS+ K +E +++Q+P + LK+ + E + G P+P ++
Sbjct: 1098 VKELHERAASQNIVVRKQEEERSRVQAPQIITQLKDDVVDEGCRYEFSARINGEPEPTIS 1157
Query: 1515 WYRDGKKLKT---AKATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
W +DG +K+ + Y N Y A N G +S + ++ +
Sbjct: 1158 WLKDGIDVKSNMDYRQEYVNGVATLVIEESFIEDTAEYTVKATNTGGTASSSASLIVKSR 1217
Query: 1571 PVIT--ISNED----IKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
++ I ED +KQ V G+ + V+ G P PE+ W+K ++ + +
Sbjct: 1218 SAMSSAILEEDKPRFVKQMQSVQVNEGETARLDCVVVGKPEPEITWFKEETAVKESERVH 1277
Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-------PSKPEGPV 1673
+T + I + + YT+ A N G + L+V K P KP P+
Sbjct: 1278 LTFSGDHCQMIIDKTVPLDTGIYTVRAKNVHGEVANFCQLRVVPKKQPPPQTPPKPRTPI 1337
Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEK---HEPDN------NRWIKVADVDRDVE 1724
+ + ++T + L++ Y K H N + +++++ +
Sbjct: 1338 QRPPVIQPALTNTTWQEGETATLQVFSYGEPKPRVHWKFNDSPVQTSSQVQISEQEDGWS 1397
Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
IQ+++ M+ V+A+N +G EA+ + ++ +L
Sbjct: 1398 RLTIQQISPVNAGMYTVVAENEIG--EAVTGATVHVQPSL 1435
Score = 52.4 bits (120), Expect = 3e-06
Identities = 41/164 (25%), Positives = 71/164 (43%), Gaps = 13/164 (7%)
Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
K + V L E E A + V+ +E + P I + ++ V E + AR+
Sbjct: 1090 KQQQVQQLVKELHERAASQNIVVRKQEEERSRVQAPQIITQLKDDVVDEGCRYEFSARIN 1149
Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
P P+I+W ++ + + Q + LVI E D+ +Y A+N+ G +S
Sbjct: 1150 GEPEPTISWLKDGIDVKSNMDYRQEYVNGVATLVIEESFIE-DTAEYTVKATNTGGTASS 1208
Query: 918 GARVTI-----------DVEKVTFVKHLQKSYETEEGKTVILEC 950
A + + + +K FVK +Q S + EG+T L+C
Sbjct: 1209 SASLIVKSRSAMSSAILEEDKPRFVKQMQ-SVQVNEGETARLDC 1251
Score = 51.6 bits (118), Expect = 6e-06
Identities = 50/196 (25%), Positives = 87/196 (44%), Gaps = 11/196 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G PP F++ + V +G E + P P++ W G + ++I V S++
Sbjct: 2309 GHPPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGRPL-DLKDIRV---SNIGG 2364
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
S L N + G Y A N G A+ L ++ + P I+ L S + +G
Sbjct: 2365 RVS-LNFQNCQLSHVGKYMCTAKNDSGVATSSAQLVVRP-KTIAPDFIQRLISEEIEEGS 2422
Query: 751 SVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGD-THSITILKPKKVKDEGVYTLK 806
+ + +V G+P P + W ++ + + + GD HS+ I+K + D G +T
Sbjct: 2423 QLKWTVRVTGDPMPKVIWMRDGFEIPDCEEVRIVDHGDGYHSLVIVKVEGA-DSGQFTCL 2481
Query: 807 AENSEGIAETSAVITV 822
AEN G A ++A + V
Sbjct: 2482 AENIAGEARSTADLVV 2497
Score = 50.4 bits (115), Expect = 1e-05
Identities = 72/352 (20%), Positives = 136/352 (38%), Gaps = 29/352 (8%)
Query: 634 PTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDMHMY 691
P F K + +Y V+EG I +EC LV P+P + F +++ E + + +D +
Sbjct: 2131 PEFIKAFEREYTVEEGGRIAIECILVGNPKPAARFFFNNKQVTEKSEFLKICHVNDTY-- 2188
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
S++ I+ K G Y ++A N+ G VL ++ + Q + ++ + +Q +
Sbjct: 2189 -SII-ISPAKLEHAGYYKMIAENKRGVTESLTVLHVRPRSLQKYQQKKQEETRMQQQARN 2246
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+ + + +P+K +K T K+++ L+ E
Sbjct: 2247 AGPTEYTTVEEEFAMFEYEQRRPLKHEASKLS------TPPPAKRIE------LEHRKDE 2294
Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
ET + E ++ PP F V + VT P P++ W +
Sbjct: 2295 EHLETYDL----EGKKKTGHPPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGR 2350
Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-- 929
+ + N G + L N G Y C A N +G ++ A++ + + +
Sbjct: 2351 PLDLKDIRVSNIGG-RVSLNFQNCQLS-HVGKYMCTAKNDSGVATSSAQLVVRPKTIAPD 2408
Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG 979
F++ L S E EEG + + + K W + EI + I+ G
Sbjct: 2409 FIQRL-ISEEIEEGSQLKWTVRVTGDPMPKVIWMRDGFEIPDCEEVRIVDHG 2459
Score = 50.0 bits (114), Expect = 2e-05
Identities = 63/299 (21%), Positives = 120/299 (40%), Gaps = 36/299 (12%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P+IIT+L++ V++G + F + + + + W KDG +++ + + L I
Sbjct: 1125 PQIITQLKDDVVDEGCRYEFSARINGEPEPTISWLKDGIDVKSNMDYRQEYVNGVATLVI 1184
Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILT---------------VEEPSINFTLRLPEFILVPA 1210
+ ++D EY+ + N+ TA + +EE F ++ +
Sbjct: 1185 EESFIEDTAEYTVKATNTGGTASSSASLIVKSRSAMSSAILEEDKPRFVKQMQSVQVNEG 1244
Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-- 1268
T V + ++TW+K+++ ++++E+ L +II K D YT
Sbjct: 1245 ETARLDCVVVGKPEPEITWFKEETAVKESERVHLTFSGDHCQMIIDKTVPLDTGIYTVRA 1304
Query: 1269 --VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR---------------GSDVTLLVDY 1311
V + + +L+V + PP + I+R G TL V
Sbjct: 1305 KNVHGEVANFCQLRVVPKKQPPPQTPPKPRTPIQRPPVIQPALTNTTWQEGETATLQVFS 1364
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHA 1369
P+P W N ++ + S S LTI+++ +AG+Y + EN G A
Sbjct: 1365 YGEPKPRVHWKFNDSPVQTSSQVQISEQEDGWSRLTIQQISPVNAGMYTVVAENEIGEA 1423
Score = 48.0 bits (109), Expect = 7e-05
Identities = 43/183 (23%), Positives = 76/183 (41%), Gaps = 18/183 (9%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P+ I +L+D V E IN E + W +DG +K + Y E + L
Sbjct: 1125 PQIITQLKDDVVDEGCRYEFSARINGEPEPTISWLKDGIDVKSNMD-YRQEYVNGVATLV 1183
Query: 1076 IRNTSVHDEGEY---------------SCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
I + + D EY S I++ S + + E P + ++Q+ +VN+
Sbjct: 1184 IEESFIEDTAEYTVKATNTGGTASSSASLIVKSRSAMSSAILEEDKPRFVKQMQSVQVNE 1243
Query: 1121 GNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
G A + + + K + + WFK+ + ++ S + LT G ++ I D G Y+
Sbjct: 1244 GETARLDCVVVGKPEPEITWFKEETAVKESERVHLTFSGDHCQMIIDKTVPLDTGIYTVR 1303
Query: 1180 VGN 1182
N
Sbjct: 1304 AKN 1306
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/95 (25%), Positives = 45/95 (47%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P+ L +G T + G P+P++ W + ++ S Q+ +D + L
Sbjct: 1341 PVIQPALTNTTWQEGETATLQVFSYGEPKPRVHWKFNDSPVQTSSQVQISEQEDGWSRLT 1400
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
I+++ P +AG +T VA+N G A + + V+ L
Sbjct: 1401 IQQISPVNAGMYTVVAENEIGEAVTGATVHVQPSL 1435
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/375 (19%), Positives = 146/375 (38%), Gaps = 33/375 (8%)
Query: 930 FVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGM-DHREIIQEGRXXXXXX 986
F+K ++ Y EEG + +EC + + +++ N K+++ + +I
Sbjct: 2133 FIKAFEREYTVEEGGRIAIECILVGNPKPAARFFFNNKQVTEKSEFLKICHVNDTYSIII 2192
Query: 987 XXXXXXDVGVIKCIVKDQETST-MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
G K I +++ T L V P ++K Q + K+++ + + N+
Sbjct: 2193 SPAKLEHAGYYKMIAENKRGVTESLTVLHVRPRSLQKYQ--QKKQEETRMQQQARNAGPT 2250
Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE- 1104
+ ++ + +++E+R ++ + ++ R + E +E
Sbjct: 2251 EYT------TVEEEFAMFEYEQRRPLKHEASKLSTPPPAKRIELEHRKDEEHLETYDLEG 2304
Query: 1105 -----LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDG 1158
PP L + V +G TFE +T A V W DG + + I+++ G
Sbjct: 2305 KKKTGHPPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGRPLDLKD-IRVSNIG 2363
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFIL------VPANT 1212
+ L +C L G+Y C N A + + T+ P+FI + +
Sbjct: 2364 GRVSLNFQNCQLSHVGKYMCTAKNDSGVATSSAQLVVRPKTI-APDFIQRLISEEIEEGS 2422
Query: 1213 DAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTC-- 1268
TV + + + V W + I D E+ ++ +L+I K D ++TC
Sbjct: 2423 QLKWTVRVTGDPMPKVIWMRDGFEIPDCEEVRIVDHGDGYHSLVIVKVEGADSGQFTCLA 2482
Query: 1269 --VLLDAKSTTKLKV 1281
+ +A+ST L V
Sbjct: 2483 ENIAGEARSTADLVV 2497
Score = 40.7 bits (91), Expect = 0.011
Identities = 48/224 (21%), Positives = 95/224 (42%), Gaps = 28/224 (12%)
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE-VEINSETADVVWERDGEIIKP 1058
IVK + + +++E P F++++Q +V E + A L+ V + ++ W ++ +K
Sbjct: 1213 IVKSRSAMSSAILEEDKPRFVKQMQSVQVNEGETARLDCVVVGKPEPEITWFKEETAVKE 1272
Query: 1059 KKNKYDFEKRGHIRKLY------------IRNTSVHDEGEYSCILR--------DESCTA 1098
+ + H + + +R +VH E C LR ++
Sbjct: 1273 SERVHLTFSGDHCQMIIDKTVPLDTGIYTVRAKNVHGEVANFCQLRVVPKKQPPPQTPPK 1332
Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEI-ELTKGDALVRWFKDGSEIQFSNHIQLT-I 1156
T ++ PP I L N +G AT ++ + V W + S +Q S+ +Q++
Sbjct: 1333 PRTPIQRPPVIQPALTNTTWQEGETATLQVFSYGEPKPRVHWKFNDSPVQTSSQVQISEQ 1392
Query: 1157 DGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI 1196
+ +L I +AG Y+ E+G + A + V +PS+
Sbjct: 1393 EDGWSRLTIQQISPVNAGMYTVVAENEIGEAVTGATVHV-QPSL 1435
Score = 38.7 bits (86), Expect = 0.045
Identities = 36/177 (20%), Positives = 70/177 (39%), Gaps = 6/177 (3%)
Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
G+ ++ G P P V W +G L+ K+ ++ + + + SH KY
Sbjct: 2326 GEATTFEGIVTGWPAPNVEWTNDGRPLDL-KDIRVSNIGGRVSLNFQNCQLSHVGKYMCT 2384
Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE--GPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
A N +G ++ L V K P+ +I EI E ++W + + + +
Sbjct: 2385 AKNDSGVATSSAQLVVRPKTIAPDFIQRLISEEI-EEGSQLKWTVRVTGDPMPKVIWMRD 2443
Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
E + +++ D + I K+ F +A+N G EA + +V++
Sbjct: 2444 GFEIPDCEEVRIVDHGDGYHSLVIVKVEGADSGQFTCLAENIAG--EARSTADLVVR 2498
Score = 38.3 bits (85), Expect = 0.059
Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 510 PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F++ ++T +G + EC + G P+P +F + +F ++ ++
Sbjct: 2131 PEFIKAFEREYTVEEGGRIAIECILVGNPKPAARFFFNNKQVTEKSEFLKICHVNDTYSI 2190
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+I E AG + +A+N G S T L V
Sbjct: 2191 IISPAKLEHAGYYKMIAENKRGVTESLTVLHV 2222
Score = 37.5 bits (83), Expect = 0.10
Identities = 32/154 (20%), Positives = 57/154 (37%), Gaps = 13/154 (8%)
Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP-PKI 1290
++S IEDT ++T+ K T + L KS + + ++E P+
Sbjct: 1185 EESFIEDTAEYTV------------KATNTGGTASSSASLIVKSRSAMSSAILEEDKPRF 1232
Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
V + ++ G L P+P W +K+ + + + I K
Sbjct: 1233 VKQMQSVQVNEGETARLDCVVVGKPEPEITWFKEETAVKESERVHLTFSGDHCQMIIDKT 1292
Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
D GIY +R +N G + ++ K PP
Sbjct: 1293 VPLDTGIYTVRAKNVHGEVANFCQLRVVPKKQPP 1326
Score = 36.7 bits (81), Expect = 0.18
Identities = 25/108 (23%), Positives = 45/108 (41%), Gaps = 2/108 (1%)
Query: 493 DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552
+ L ++ ++ P F + L G FE V G+P P + W +
Sbjct: 2295 EHLETYDLEGKKKTGHPPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGRPLD- 2353
Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+D ++ V+ L + G + C AKN +G A+S+ +L+V
Sbjct: 2354 LKDIRVSNIGGRVS-LNFQNCQLSHVGKYMCTAKNDSGVATSSAQLVV 2400
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 3/115 (2%)
Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
A S+ +L V P + I+ GS + V P P W+ + I C+
Sbjct: 2392 ATSSAQLVVRPKTIAPDFIQRLISEEIEEGSQLKWTVRVTGDPMPKVIWMRDGFEIPDCE 2451
Query: 1333 HTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
+ +D SL I KVE D+G + EN G A ++ + + + PG
Sbjct: 2452 EVR-IVDHGDGYHSLVIVKVEGADSGQFTCLAENIAGEARSTADLVVRPQGTAPG 2505
>U80438-4|AAB37634.2| 1415|Caenorhabditis elegans Uncoordinated
protein 40 protein.
Length = 1415
Score = 115 bits (277), Expect = 3e-25
Identities = 135/605 (22%), Positives = 230/605 (38%), Gaps = 51/605 (8%)
Query: 1479 IQSPTVEKPLKNITT------EPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE 1530
+ + TV L ITT E ++ L C+ + +P+V W +D +++ +
Sbjct: 236 VTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVDGVRIRRV 295
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW 1590
Y C A N+ ++ + V ++ P IT + K + D
Sbjct: 296 GVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRAPPRIT-TRPTTKVAVETADVE 354
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
L P V WYKNG + EY + + +RI + R+ + Y A N
Sbjct: 355 LECGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNR---LRILGVVRADQAIYQCIAEND 410
Query: 1651 AGT--SSVEVTLKVYDK---------PSKPEGPVIMREISRES--VTIEWKPPLDDGGLE 1697
G+ +S ++ + D P P+ +R S S + +EW PP+ G
Sbjct: 411 VGSEQASAQLLVDAPDSSSVAASSGVPMTSSAPLGLRSTSSGSRFINVEWDPPVQRNG-N 469
Query: 1698 LTKYAI--EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
+ +Y I + + D R I + + + L + Y+ RV A+N G + +S
Sbjct: 470 IMRYHIFYKDNLIDRERMINSSST-----SATLTSLQPSTMYLIRVTAENEAGMGKFSDS 524
Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ---EGKK 1812
+ VP E++ I W P +GG P + YK+ E +
Sbjct: 525 LKVTTNKEQAVPGKVASLTTTAT-GPETIDIRWSP--PSGGQPALRYKIFYSHDPLEKNE 581
Query: 1813 WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR-N 1871
+ + + T YQ RI A G+ L S D + + PS P N
Sbjct: 582 KETLITTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGL---SSDTVKVRTQSDEPSAPPVN 638
Query: 1872 FVVSESTSRSVTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+S SV + W EPE IT Y +++KT + + + + E+ + N+
Sbjct: 639 IQAEADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYTMGNL 698
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-MVGSNIVMTSWGT 1989
+ + + R++ N G ++ S+ AP EIR G + ++ SW
Sbjct: 699 EPNTQYLIRMAVVNHNGTGPFSDWVSIDTPGQDKEERTLGAPREIRPHAGIDYILVSW-L 757
Query: 1990 PEWDGGAPLLGYNIAI-RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P D + GY I V T E +V +T ++ I L Y+I + A N +G
Sbjct: 758 PPADEQNLVRGYQIGWGLSVPDT---ETIRVTASTTQYKIARLHSERDYVISLRAFNNLG 814
Query: 2049 LSEPL 2053
P+
Sbjct: 815 SGFPI 819
Score = 70.1 bits (164), Expect = 2e-11
Identities = 62/281 (22%), Positives = 107/281 (38%), Gaps = 21/281 (7%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
+G C + + P P WL E IV + S+ L+I++ + EG
Sbjct: 161 KGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSN------TLEISSTQSRHEG 214
Query: 707 TYTVV---AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
TY A R + + + +T E + P + +V QG+ +L V R
Sbjct: 215 TYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTP-RLQVVEQGDEFLLECLVASLIR 273
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
P + W K+++ + + S ++ ++D G+YT +A N++ + + + V
Sbjct: 274 PQVRWLKDSRQIIVDGVRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVR 333
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
P P ++ V+ P + WY+N E I SE F
Sbjct: 334 APPRITTRPT------TKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSE----YF 383
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
E L I V D Y+C+A N G A++ +D
Sbjct: 384 VIEPNRLRILGV-VRADQAIYQCIAENDVGSEQASAQLLVD 423
Score = 54.0 bits (124), Expect = 1e-06
Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 13/191 (6%)
Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
F P+ Q V++G + LLEC + ++ P + WL +I+ D V I + S +
Sbjct: 247 FITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVD---GVRIR---RVGVSSI 300
Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVIL 754
++ G YT A N + + ++++ PP++ P + V + +
Sbjct: 301 LVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRA----PPRITTRPTTKVAVETADVELE 356
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
P + W KN + + + + + IL + D+ +Y AEN G
Sbjct: 357 CGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNRLRILGVVRA-DQAIYQCIAENDVGSE 414
Query: 815 ETSAVITVEEP 825
+ SA + V+ P
Sbjct: 415 QASAQLLVDAP 425
Score = 37.1 bits (82), Expect = 0.14
Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 9/109 (8%)
Query: 1358 YKLRLE----NNCGHADVEMNV-TILDKPSPPGKPNILEIDSS-SINICWDEPENTG-NS 1410
Y++R+E N G + + V T D+PS P E DSS S+ + WDEPE N
Sbjct: 604 YQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQAEADSSTSVRVSWDEPEEESVNG 663
Query: 1411 TIIYYVVEY--QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
I Y ++Y + V + T + ++ NL+ N+ Y R VN
Sbjct: 664 EITGYRLKYKTKARGAKGNTLVIDATAREYTMGNLEPNTQYLIRMAVVN 712
Score = 35.9 bits (79), Expect = 0.32
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 5/103 (4%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT-AIIKPSQDFQMYY 560
T+E S +F+ R + G EC V RPQ+ W + + II +
Sbjct: 237 TTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVDGVRIRRV- 295
Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
V+++++ ED G +TC A N + V AP
Sbjct: 296 ---GVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRAP 335
Score = 34.3 bits (75), Expect = 0.97
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 6/106 (5%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC-QVEGYPRPQITWFRQTAIIKPSQDFQ 557
++ S E P + K + + V+ EC P ++ W++ I S+ F
Sbjct: 325 DRAVSVEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSEYFV 384
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + N L I V D + C+A+N G ++ +L+V+AP
Sbjct: 385 I---EPN--RLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAP 425
Score = 33.9 bits (74), Expect = 1.3
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAI-PEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP + +P + E +D+ LEC A PE + W GE I+ E IE +
Sbjct: 335 PPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSEYF--VIEPNR--- 389
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREG 717
L+I V + + Y +A N G
Sbjct: 390 ---LRILGVVRADQAIYQCIAENDVG 412
>U70618-1|AAB17088.1| 1415|Caenorhabditis elegans unc-40 protein.
Length = 1415
Score = 115 bits (277), Expect = 3e-25
Identities = 135/605 (22%), Positives = 230/605 (38%), Gaps = 51/605 (8%)
Query: 1479 IQSPTVEKPLKNITT------EPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE 1530
+ + TV L ITT E ++ L C+ + +P+V W +D +++ +
Sbjct: 236 VTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVDGVRIRRV 295
Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW 1590
Y C A N+ ++ + V ++ P IT + K + D
Sbjct: 296 GVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRAPPRIT-TRPTTKVAVETADVE 354
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
L P V WYKNG + EY + + +RI + R+ + Y A N
Sbjct: 355 LECGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNR---LRILGVVRADQAIYQCIAEND 410
Query: 1651 AGT--SSVEVTLKVYDK---------PSKPEGPVIMREISRES--VTIEWKPPLDDGGLE 1697
G+ +S ++ + D P P+ +R S S + +EW PP+ G
Sbjct: 411 VGSEQASAQLLVDAPDSSSVAASSGVPMTSSAPLGLRSTSSGSRFINVEWDPPVQRNG-N 469
Query: 1698 LTKYAI--EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
+ +Y I + + D R I + + + L + Y+ RV A+N G + +S
Sbjct: 470 IMRYHIFYKDNLIDRERMINSSST-----SATLTSLQPSTMYLIRVTAENEAGMGKFSDS 524
Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ---EGKK 1812
+ VP E++ I W P +GG P + YK+ E +
Sbjct: 525 LKVTTNKEQAVPGKVASLTTTAT-GPETIDIRWSP--PSGGQPALRYKIFYSHDPLEKNE 581
Query: 1813 WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR-N 1871
+ + + T YQ RI A G+ L S D + + PS P N
Sbjct: 582 KETLITTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGL---SSDTVKVRTQSDEPSAPPVN 638
Query: 1872 FVVSESTSRSVTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
+S SV + W EPE IT Y +++KT + + + + E+ + N+
Sbjct: 639 IQAEADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYTMGNL 698
Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-MVGSNIVMTSWGT 1989
+ + + R++ N G ++ S+ AP EIR G + ++ SW
Sbjct: 699 EPNTQYLIRMAVVNHNGTGPFSDWVSIDTPGQDKEERTLGAPREIRPHAGIDYILVSW-L 757
Query: 1990 PEWDGGAPLLGYNIAI-RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
P D + GY I V T E +V +T ++ I L Y+I + A N +G
Sbjct: 758 PPADEQNLVRGYQIGWGLSVPDT---ETIRVTASTTQYKIARLHSERDYVISLRAFNNLG 814
Query: 2049 LSEPL 2053
P+
Sbjct: 815 SGFPI 819
Score = 70.1 bits (164), Expect = 2e-11
Identities = 62/281 (22%), Positives = 107/281 (38%), Gaps = 21/281 (7%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
+G C + + P P WL E IV + S+ L+I++ + EG
Sbjct: 161 KGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSN------TLEISSTQSRHEG 214
Query: 707 TYTVV---AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
TY A R + + + +T E + P + +V QG+ +L V R
Sbjct: 215 TYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTP-RLQVVEQGDEFLLECLVASLIR 273
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
P + W K+++ + + S ++ ++D G+YT +A N++ + + + V
Sbjct: 274 PQVRWLKDSRQIIVDGVRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVR 333
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
P P ++ V+ P + WY+N E I SE F
Sbjct: 334 APPRITTRPT------TKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSE----YF 383
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
E L I V D Y+C+A N G A++ +D
Sbjct: 384 VIEPNRLRILGV-VRADQAIYQCIAENDVGSEQASAQLLVD 423
Score = 54.0 bits (124), Expect = 1e-06
Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 13/191 (6%)
Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
F P+ Q V++G + LLEC + ++ P + WL +I+ D V I + S +
Sbjct: 247 FITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVD---GVRIR---RVGVSSI 300
Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVIL 754
++ G YT A N + + ++++ PP++ P + V + +
Sbjct: 301 LVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRA----PPRITTRPTTKVAVETADVELE 356
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
P + W KN + + + + + IL + D+ +Y AEN G
Sbjct: 357 CGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNRLRILGVVRA-DQAIYQCIAENDVGSE 414
Query: 815 ETSAVITVEEP 825
+ SA + V+ P
Sbjct: 415 QASAQLLVDAP 425
Score = 37.1 bits (82), Expect = 0.14
Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 9/109 (8%)
Query: 1358 YKLRLE----NNCGHADVEMNV-TILDKPSPPGKPNILEIDSS-SINICWDEPENTG-NS 1410
Y++R+E N G + + V T D+PS P E DSS S+ + WDEPE N
Sbjct: 604 YQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQAEADSSTSVRVSWDEPEEESVNG 663
Query: 1411 TIIYYVVEY--QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
I Y ++Y + V + T + ++ NL+ N+ Y R VN
Sbjct: 664 EITGYRLKYKTKARGAKGNTLVIDATAREYTMGNLEPNTQYLIRMAVVN 712
Score = 35.9 bits (79), Expect = 0.32
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 5/103 (4%)
Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT-AIIKPSQDFQMYY 560
T+E S +F+ R + G EC V RPQ+ W + + II +
Sbjct: 237 TTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVDGVRIRRV- 295
Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
V+++++ ED G +TC A N + V AP
Sbjct: 296 ---GVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRAP 335
Score = 34.3 bits (75), Expect = 0.97
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 6/106 (5%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC-QVEGYPRPQITWFRQTAIIKPSQDFQ 557
++ S E P + K + + V+ EC P ++ W++ I S+ F
Sbjct: 325 DRAVSVEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSEYFV 384
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+ + N L I V D + C+A+N G ++ +L+V+AP
Sbjct: 385 I---EPN--RLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAP 425
Score = 33.9 bits (74), Expect = 1.3
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAI-PEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP + +P + E +D+ LEC A PE + W GE I+ E IE +
Sbjct: 335 PPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSEYF--VIEPNR--- 389
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREG 717
L+I V + + Y +A N G
Sbjct: 390 ---LRILGVVRADQAIYQCIAENDVG 412
>AF106579-2|AAM45363.1| 4447|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform c protein.
Length = 4447
Score = 113 bits (273), Expect = 1e-24
Identities = 114/465 (24%), Positives = 191/465 (41%), Gaps = 64/465 (13%)
Query: 493 DKLPVFEKPTSEEQSMA--PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550
D + + +PT QS P ++L+P G +F + G ++TW + I
Sbjct: 4011 DAVQLKPQPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEI 4070
Query: 551 KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
K + + N ++L I + AG +T +NAAG S L V P +
Sbjct: 4071 KSTFRTLITTTPTN-SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTT----- 4124
Query: 611 MTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFK 670
+G P FS + + + C++ P+P I W
Sbjct: 4125 -------------------QGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKD 4165
Query: 671 GEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI--- 727
G+ + D+ V E + LK +N+ G Y +VA N GEA L +
Sbjct: 4166 GQPLPNDDRFQVVEEGGAYK----LKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQ 4221
Query: 728 KTGEK-------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780
KTG+ E P+ ++ ++V +G+ SAQ G P PTI W +NN+PVK
Sbjct: 4222 KTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADG 4281
Query: 781 KSDGDTHSITILKPKKVKDEGV--YTLKAENSEGIAETSA--VIT--------------- 821
+ IL+ ++E V Y ++A N G A + A V+T
Sbjct: 4282 YEISQSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGG 4341
Query: 822 ---VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
+ + A+ P FI + +I+ ++ T+K A V NP P++ W + IS S
Sbjct: 4342 SASYQSSDKAAADSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNN 4401
Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ + DG+ L + V + +G+Y+ V N G ++ A++T+
Sbjct: 4402 VKISRDGKRAILELARVTPD-SAGEYQIVIRNDKGAATSQAKLTL 4445
Score = 86.2 bits (204), Expect = 2e-16
Identities = 68/298 (22%), Positives = 131/298 (43%), Gaps = 18/298 (6%)
Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
KI +++ E V+++ P KI ++ PP + + LK + G++
Sbjct: 3991 KIKEIQQKPEQPKEEPIVHKDAVQLKPQPTKIGQSKQAPPTISQQLKPLQGELGKAAKFV 4050
Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE--GVYTLKAENSEGI 813
+ G +TW K+ K +K+ T + + L ++++ G YT++ EN+ G
Sbjct: 4051 IEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGT 4110
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
E+ A +TV PT + P F R ++ +++ G + ++ P P+I W+++ + +
Sbjct: 4111 VESLANLTVAPPTTQGKAPD-FSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPL 4169
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
+ +G +L +N+ S D+G Y+ VA N G++ AR+ ++++K
Sbjct: 4170 PNDDRFQVVEEGGAYKLKFSNIIS-TDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAE 4228
Query: 934 LQKSYE------------TEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977
YE +EGK Q S + +WY N + + D EI Q
Sbjct: 4229 EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQ 4286
Score = 76.6 bits (180), Expect = 2e-13
Identities = 53/195 (27%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSI 789
PPQ + +S+ + E+V SA+VVG P P++TW K++ V ++ D
Sbjct: 304 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGR 363
Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
I++ D +Y L A N G ++ + V + ++ E P F +FQ T+ + +
Sbjct: 364 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQ--AKSPEAPEFTGKFQSTTLYDGDS 421
Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
+KL + V S W+++NE IS + + G L I N + + G Y+C A+
Sbjct: 422 VKLYCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMK-EGGWYRCDAT 479
Query: 910 NSAGKSSHGARVTID 924
N G ++ RV ++
Sbjct: 480 NKHGTTTLKGRVVVN 494
Score = 66.1 bits (154), Expect = 3e-10
Identities = 119/539 (22%), Positives = 206/539 (38%), Gaps = 81/539 (15%)
Query: 474 LMDENNYTQYLQKKLN-EKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFEC 531
L+ + ++ LQK E IDK + P E + P +V+ ++ +G TV
Sbjct: 2351 LLLDTSHPASLQKIQELEAIDKYARLDAPEREYEK--PQWVQGFENYENVGEGQTVTLHG 2408
Query: 532 QVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
VE G P ++ W ++ + F+ Y+ N A L I V P D+G +TC A N
Sbjct: 2409 LVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN-AILTIVHVLPHDSGVYTCRAWNTQ 2467
Query: 590 GFASSTTELIV---EAPLSDHGSEMT---VXXXXXXXXXXXXADILEGIPPTF-SKKPKA 642
G AS++ + E L D ++ + +I++ P F ++ A
Sbjct: 2468 GEASTSATVTTAGYEKILYDSQHPVSWERIQELEAPKIVEEIEEIVQKEKPNFLTQLESA 2527
Query: 643 QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDE-----------NISVAIESDMH 689
+ V EG + LE +P+ + W G+ + + + ++ ++ H
Sbjct: 2528 ENVPEGVPLHLESTFQPARDPELKVVWQKNGQPLGASQLVQTKHELGWATLDISSANEDH 2587
Query: 690 MYCSVLKITNVKKFQ--------EGTYTVVAVNREGEASLPIVLKIKTGEKEP------- 734
L ITN + GT ++ R E+ I + E EP
Sbjct: 2588 NGVYTLTITNSEGEAVSTASIRVAGTGPILGNTRHEESWKRIQILEAPKEAEPEAPAPVY 2647
Query: 735 --PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
P + + +G+ V A + V +PR + W +N P+ + I
Sbjct: 2648 DHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQVQWIRNGVPLAHGSKYAIQQDFGIC 2707
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVI----------------------TVEEPT 826
L +DEGVY L+ N EG A +SA + +E P
Sbjct: 2708 TLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCHGKDAILGDVQHQESWKRIQEIEAPK 2767
Query: 827 EENAE-------PPLFINRFQ---EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
++ E PP FI + + + + +P +I W+ N E +S S
Sbjct: 2768 QKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSAS 2827
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
+ D + + I + DSG++KCVA N+AG++ A + + ++V LQ
Sbjct: 2828 SRVKMINDFGWVIMDIAQTEPR-DSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQ 2885
Score = 64.1 bits (149), Expect = 1e-09
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 23/248 (9%)
Query: 500 KPTSEEQS-MAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQ 554
KP+ ++ + P+F ++L P +G +V +C V+ P +I WF +
Sbjct: 1581 KPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGS 1640
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDH- 607
+ +D V L + PED GT+TC A N G +TT++ +E L H
Sbjct: 1641 RIRTIHDFGYVG-LEFLHIHPEDTGTYTCKATNLIG--EATTDIFLECKPRRNIYLDTHH 1697
Query: 608 -GSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD- 664
S + L PPTF++ + EG I LECRL+ + +P
Sbjct: 1698 ESSWQKIQEIENRVDEREPTPELTFQPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTM 1757
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+ W G+ + A D Y + L I + G YT AV+ GEA+
Sbjct: 1758 RVTWTRNGQPLPEASRFMPARNFD---YVN-LDILALYGEDSGVYTCKAVSAFGEAATSC 1813
Query: 724 VLKIKTGE 731
+K G+
Sbjct: 1814 TVKCAAGK 1821
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/319 (22%), Positives = 119/319 (37%), Gaps = 27/319 (8%)
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
+ PP I +L+ + G A F IE + V W KDG EI+ + +T
Sbjct: 4027 QAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSS 4086
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCT----AILTVEEPSI-----NFTLRLPEFILVPANTD 1213
L I + AGEY+ + N+ T A LTV P+ +F+ RL + + + N
Sbjct: 4087 LHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLND-LRIQQNGP 4145
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271
A + +I E + W+K + + ++F ++ + L D Y V
Sbjct: 4146 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4205
Query: 1272 ---DAKSTTKLKVEVV-------EFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+A+ +L V + E P P+ + + G + FP P
Sbjct: 4206 GVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDP 4265
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W N++ +K + S A L I N D YK+ N G A N+ +
Sbjct: 4266 TIRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVL 4325
Query: 1378 LDKPSPPGKPNILEIDSSS 1396
+ K I S+S
Sbjct: 4326 TPRSGRIAKSTISRGGSAS 4344
Score = 62.1 bits (144), Expect = 4e-09
Identities = 83/338 (24%), Positives = 135/338 (39%), Gaps = 32/338 (9%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
P F L P +G ECQV PR I WF + + + +D V
Sbjct: 3183 PKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIHDFGFVV 3242
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---------PLSDHGSEMT-VXXX 616
L + P+D+GT+TC A N G +TEL V ++ +T +
Sbjct: 3243 -LQLTPAEPQDSGTWTCRATNQHGSDEVSTELKVVGGGGVSYEWQSTAERKERITELEDW 3301
Query: 617 XXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
++ P+FS+ ++E C L I +P + W G
Sbjct: 3302 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHP 3361
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK- 732
I IS E + + L I ++ G Y VA N +G A+ + +++ +
Sbjct: 3362 IPYSNRISCTNEFGV----ATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQI 3417
Query: 733 EPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDG 784
+ PQV++ L + + +G+S+ L +V + +PR + W +N P+ + PT G
Sbjct: 3418 DAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFG 3477
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S+ IL +D G Y L N +G A + ITV
Sbjct: 3478 FV-SLDILYAYP-EDNGDYELVVRNDKGEARSKTKITV 3513
Score = 60.1 bits (139), Expect = 2e-08
Identities = 57/222 (25%), Positives = 91/222 (40%), Gaps = 17/222 (7%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F K + DG +V+ C+ G WF+ I + + + N TL
Sbjct: 404 APEFTGKFQSTTLYDGDSVKLYCKAAG-EGVSFKWFKDNEPISSGGSYAVD-NKGNETTL 461
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS---EM-TVXXXXXXXXXXX 624
I ++ G + C A N G + ++V + +G EM T+
Sbjct: 462 HINNATMKEGGWYRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREMITLRKVDKVERSRT 521
Query: 625 XADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPD 677
+ L+ + P F ++Q + EG LE + + +P+ IAWL G+ I+
Sbjct: 522 PVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILAS 581
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I + + + L+I V F +G YTVVAVN GEA
Sbjct: 582 SRIVTFTDFGI----AALEINPVNVFDQGEYTVVAVNPLGEA 619
Score = 59.3 bits (137), Expect = 3e-08
Identities = 43/197 (21%), Positives = 80/197 (40%), Gaps = 20/197 (10%)
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRX 1533
T+ ++P L ++ + N E +C GG P+P + W++DG+ L + E
Sbjct: 4124 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 4183
Query: 1534 XXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVGIQ--------------QKPVITISNE 1578
Y+ +A N GE + + + P T +
Sbjct: 4184 YKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQ 4243
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
I G ++ +A G P P + WY+N +++ Y I+ + +++RI +
Sbjct: 4244 PIVVDEGKGAQF--SAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4301
Query: 1639 HSSKYTIEASNTAGTSS 1655
++Y +EASN AG +S
Sbjct: 4302 DVAEYKVEASNPAGKAS 4318
Score = 55.6 bits (128), Expect = 4e-07
Identities = 51/192 (26%), Positives = 81/192 (42%), Gaps = 15/192 (7%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDG 885
NA PP F+ Q + K T+ A+V P PS+TW +++ + S I DG
Sbjct: 301 NARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDG 360
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV------EKVTFVKHLQKSYE 939
L+I VD+ D+ Y VA N G S +R +++V E F Q S
Sbjct: 361 SG-RLIIEKVDAH-DADMYMLVARNDGG--SFQSRFSLNVLQAKSPEAPEFTGKFQ-STT 415
Query: 940 TEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
+G +V L C+ + VS KW+ + + IS + +G + G +
Sbjct: 416 LYDGDSVKLYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYR 475
Query: 999 CIVKDQETSTML 1010
C ++ +T L
Sbjct: 476 CDATNKHGTTTL 487
Score = 54.8 bits (126), Expect = 6e-07
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+Q AP F LR + +FEC V GYPRP++TWF F++ +D +
Sbjct: 3692 KQKQAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLH 3751
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
T+ + DAG +A+N G ST L
Sbjct: 3752 YLTVSKSRI--SDAGEVVAIARNTEGETISTATL 3783
Score = 53.6 bits (123), Expect = 1e-06
Identities = 49/212 (23%), Positives = 82/212 (38%), Gaps = 15/212 (7%)
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKATY 1529
I ++K PT+ + LK + E + + F G KVTW +DGK++K T T
Sbjct: 4022 IGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTT 4081
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQK 1583
Y N G VE+ + + + P + D++ +
Sbjct: 4082 PTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQ 4141
Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
E+ + I G P P + W+K+G L ND + + + ++ + + + Y
Sbjct: 4142 QNGPAEF--SCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIY 4199
Query: 1644 TIEASNTAGTSSVEVTLKV-YDKPSK--PEGP 1672
I A N G + + L V K K EGP
Sbjct: 4200 EIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4231
Score = 53.2 bits (122), Expect = 2e-06
Identities = 56/223 (25%), Positives = 85/223 (38%), Gaps = 17/223 (7%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P F+++L P + FE VE P +T WF + S +M +D
Sbjct: 2781 PRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMI-NDFGWV 2839
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTT-------ELIVEAPLSDHGSEMTVXXXXXX 619
+ I + P D+G + CVAKNAAG A ST E+I++ L +
Sbjct: 2840 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEAGK 2899
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVPD 677
D P + ++EG L+ + + +P I WL G+ I
Sbjct: 2900 PAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHS 2959
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
+ + +VL I ++ K G YT N GEAS
Sbjct: 2960 NRYKMVHDFGF----AVLDILHLLKHDAGEYTFRVSNNSGEAS 2998
Score = 52.8 bits (121), Expect = 3e-06
Identities = 59/241 (24%), Positives = 93/241 (38%), Gaps = 17/241 (7%)
Query: 491 KIDKLPVFEKPTSEEQSMA-----PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITW 543
K+DK+ P ++ Q ++ P F L+ + +G + + E + P +I W
Sbjct: 512 KVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAW 571
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
I S + + D +A L I V D G +T VA N G A + + V
Sbjct: 572 LLNGKGILASSRI-VTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGEARVSANIAVIGH 630
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIP---PTFSKKPKAQYVDEGSDILLECRLVAI 660
S + + A G P F ++Q V EG I LE +L I
Sbjct: 631 GSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKLTPI 690
Query: 661 PEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+PD + WL G E+ ++ + H + S L I G Y+ A N+ GE
Sbjct: 691 NDPDLRVVWLLDGNELPSNDKYRQTLS---HGFAS-LDIPQTSSNDSGLYSCRAFNKLGE 746
Query: 719 A 719
+
Sbjct: 747 S 747
Score = 52.0 bits (119), Expect = 5e-06
Identities = 64/265 (24%), Positives = 102/265 (38%), Gaps = 22/265 (8%)
Query: 470 PAQYLMDENNYTQYLQK-KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGST 526
PA ++ + + + L K E ++K E Q P FV L+ +G
Sbjct: 1154 PAGQILSDTQHQESLGKINYLENLNKYGRVEIEDKGPQE-PPTFVVPLQADLGDVEEGEP 1212
Query: 527 VQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
+ ECQV +I W R + F+ +YD V+ L I + +DAGT+TC
Sbjct: 1213 IHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFYDFGFVS-LDILGFYAQDAGTYTCR 1271
Query: 585 AKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
A+N+ G A + + + + S + L PP F K
Sbjct: 1272 AENSLGQAETVATIRCAPKDAILGAVQHPRSYARIQEIEAPKPAPQEVPDLPHQPPAFVK 1331
Query: 639 K--PKAQYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSV 694
+ P Q + EG ++ LE ++ + + WL G+ ++ + D
Sbjct: 1332 QLGPAIQCM-EGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRF--VLSQDFGYI--A 1386
Query: 695 LKITNVKKFQEGTYTVVAVNREGEA 719
L I GTYT+V NR GEA
Sbjct: 1387 LNILYCYPEDNGTYTLVVRNRAGEA 1411
Score = 51.6 bits (118), Expect = 6e-06
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 1191 VEEPSINFTLRLPEF-ILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISD 1247
V+ P+ +F+ L + L A+ A++ V P D TL V W I + + + ++
Sbjct: 3314 VDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNE 3373
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP-----PKIVDY--EREYRI 1299
TL+I+ D EY CV + K S T + VE P++V + I
Sbjct: 3374 FGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENI 3433
Query: 1300 KRGSDVTLLVDYQAFPQP--NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
G + L P + EW+ N + + KP+ + SL I D G
Sbjct: 3434 LEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFVSLDILYAYPEDNGD 3493
Query: 1358 YKLRLENNCGHADVEMNVTILDKPS 1382
Y+L + N+ G A + +T+L +PS
Sbjct: 3494 YELVVRNDKGEARSKTKITVLPRPS 3518
Score = 50.8 bits (116), Expect = 1e-05
Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 23/273 (8%)
Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR-PKHTPDGSTVQFECQ 532
L +N + L + + + P E+ E + P+F+E L P T +G F +
Sbjct: 3013 LQPQNEQKAKAVEILEDNLRRRP--EEIEQELKEATPVFIEPLSAPVETEEGGRAHFTAR 3070
Query: 533 VEGYP--RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
E + Q+ W+ +K + + L I +PED G + C A N G
Sbjct: 3071 YEPVNDNQLQVQWYHDGRPLKNGSRIKTI-NSFGYVVLEISPTYPEDNGEYICRAVNRVG 3129
Query: 591 FASSTTEL-------IVEA---PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKK 639
A ++T+L I+ A P + + A + PP F S
Sbjct: 3130 EAVTSTKLTCTPKEGIISATQLPERMANAGRRIAEIEAPRPAREDAPDADHGPPKFTSAL 3189
Query: 640 PKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
+ EG LEC++ + +P I W G+ + N + +++ VL++
Sbjct: 3190 AGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPV----NHTNRMKAIHDFGFVVLQL 3245
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730
T + GT+T A N+ G + LK+ G
Sbjct: 3246 TPAEPQDSGTWTCRATNQHGSDEVSTELKVVGG 3278
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816
+G+P + W N P+ S + + L K + D G Y A N +G A +
Sbjct: 3346 IGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATS 3405
Query: 817 SAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVT--RNPVPSITWYRNNEII 873
I VE T+ +A P + + + E +I L RVT +P + W RN +
Sbjct: 3406 VGKIAVESSTQIDA-PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPL 3464
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ F+ + L I E D+GDY+ V N G++ ++T+
Sbjct: 3465 PEASRFKPTFEFGFVSLDILYAYPE-DNGDYELVVRNDKGEARSKTKITV 3513
Score = 48.4 bits (110), Expect = 6e-05
Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 20/243 (8%)
Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
E+P AP F +L K + V FE ++ + + W+ + +
Sbjct: 916 ERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAAHR 975
Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP----LSDHGSE- 610
F +D VA L + +P+D+GT+T VA+N G A S EL+V L H E
Sbjct: 976 FHPMFDFGYVA-LDLLYAYPQDSGTYTLVARNELGEARSNVELVVGTEKVLYLEPHHPEG 1034
Query: 611 MTVXXXXXXXXXXXXADI----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD-- 664
+ A++ + P + P Q ++E +I ++ R + +P
Sbjct: 1035 LERIKELEQDRRQGIAEVEDRTCDAAPKFLNDLPDIQ-LNEHENIHVDLRATPVNDPTMV 1093
Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
I W G ++ + E L I GTY+V A N GEA V
Sbjct: 1094 IEWFVNGRPLLTGSRVKTLNEFGF----IALDIKGAIAEDSGTYSVRASNLLGEAIRQCV 1149
Query: 725 LKI 727
+ +
Sbjct: 1150 ITV 1152
Score = 48.4 bits (110), Expect = 6e-05
Identities = 52/257 (20%), Positives = 97/257 (37%), Gaps = 24/257 (9%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PP I + + + G ++++ W+ + K IK T + ++SL
Sbjct: 4029 PPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLH 4088
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
I ++EN+ AG Y +RLEN G + N+T+ P+ GK + + I + P
Sbjct: 4089 IGRLENSHAGEYTVRLENAAGTVESLANLTVA-PPTTQGKAPDFSARLNDLRIQQNGPAE 4147
Query: 1407 TG------NSTIIYYVVEYQEIDTTEWISV-----------KNITKTQTSIQNL-KTNSS 1448
I + + Q + + V NI T I + N
Sbjct: 4148 FSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGV 4207
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
R A V++ + E + + ++P ++ I + + + + F G
Sbjct: 4208 GEARCKARLNVNLQKTGKGAE-----EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGF 4262
Query: 1509 PQPKVTWYRDGKKLKTA 1525
P P + WYR+ + +K A
Sbjct: 4263 PDPTIRWYRNNEPVKHA 4279
Score = 46.4 bits (105), Expect = 2e-04
Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 506 QSMAPIFVEKLRPKHTPDG-STVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDD 562
Q + P F+ +++P H FE +++ P +++W + + + Q++ +
Sbjct: 785 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIF-QN 843
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
V +L + +PEDAG +TCV N+ G A S+ EL
Sbjct: 844 FGVVSLSLHPTYPEDAGVYTCVLFNSHGQAQSSAEL 879
Score = 46.0 bits (104), Expect = 3e-04
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 11/157 (7%)
Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQVV--GNPRPTITWCKNNKPVKA---LPTKSDGDT 786
E P ++PL+S+ + +G +L A++V +P + W N++P+ + T +D
Sbjct: 2251 EKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMESNWISTSNDFGC 2310
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITV 844
S+ I P + GVY+ KA N G A TSA + V+ E + P + + QE+
Sbjct: 2311 VSLRIA-PVYARHTGVYSCKAWNDSGNAVTSANVGVQGSEGLLLDTSHPASLQKIQELEA 2369
Query: 845 KEKGTIKLVARVTRNPVPS-ITWYRNNEIISPSETIT 880
+K +L A P + + N E + +T+T
Sbjct: 2370 IDK-YARLDAPEREYEKPQWVQGFENYENVGEGQTVT 2405
Score = 46.0 bits (104), Expect = 3e-04
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L+++NVKK + Y + +G A P +K+ PQ PL+++ V + +
Sbjct: 3668 LRVSNVKKDNKNIYW----SEQGGAVQP-------KQKQAPQFTIPLRNLQVTENQPARF 3716
Query: 755 SAQVVGNPRPTITWCKN-NKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENSEG 812
V G PRP +TW N N+ + K + D H +T+ K ++ D G A N+EG
Sbjct: 3717 ECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSK-SRISDAGEVVAIARNTEG 3775
Query: 813 IAETSAVITV 822
++A + +
Sbjct: 3776 ETISTATLDI 3785
Score = 45.6 bits (103), Expect = 4e-04
Identities = 55/231 (23%), Positives = 89/231 (38%), Gaps = 18/231 (7%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDF 556
EKP +E AP F+E L + + F+ +V + P +I WF+ + S F
Sbjct: 1981 EKPDAEHD--APQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRF 2038
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMT- 612
++ D ++ L I PED+G ++ A NA G A +L V L D E +
Sbjct: 2039 KLTTDFGYIS-LDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTVTGNAVILGDTQHEQSW 2097
Query: 613 ---VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAW 667
D+ G P ++ V EG E + + +P + W
Sbjct: 2098 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 2157
Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
G + + + +D + L+ T + G Y+VV N EGE
Sbjct: 2158 YLNGNPL--SASSRRILRNDFGLVSLDLQYTLGE--DAGEYSVVVKNSEGE 2204
Score = 44.8 bits (101), Expect = 7e-04
Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 17/197 (8%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE- 601
W +K S +++ +D +L I + ED+G +T V N+AG A ++ E V+
Sbjct: 1496 WLFNGNPLKASSRYRVL-NDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVDR 1554
Query: 602 --APLSD--HGSEM-TVXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLE 654
+ LSD H + + D PP F+++ + + EG + ++
Sbjct: 1555 LKSILSDTAHPESLRRIREMEQLQPAKPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMD 1614
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVV 711
C + I +P I W G ++ I +H + V L+ ++ GTYT
Sbjct: 1615 CVVQPINDPSLRIEWFHDGRPLMFGSRIRT-----IHDFGYVGLEFLHIHPEDTGTYTCK 1669
Query: 712 AVNREGEASLPIVLKIK 728
A N GEA+ I L+ K
Sbjct: 1670 ATNLIGEATTDIFLECK 1686
Score = 44.8 bits (101), Expect = 7e-04
Identities = 63/285 (22%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
K+ P ++L+ + + A +E + V W +DG+ IK +
Sbjct: 4026 KQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTN- 4084
Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE-----LPPEIITRLQNQKVNKGN 1122
L+I GEY+ L + + T E +TV P+ RL + ++ +
Sbjct: 4085 SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNG 4144
Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
A F ++ + ++WFKDG + + Q+ +G KLK + DAG Y
Sbjct: 4145 PAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAK 4204
Query: 1179 -EVGNSKCTAILTV----------EEP---SINFTLRLPEFILVPANTDAYLTVE---IP 1221
VG ++C A L V E P + FT ++ + I+V A + + P
Sbjct: 4205 NGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQI-QPIVVDEGKGAQFSAQFSGFP 4263
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
D T + WY+ ++ + + + + L I +D EY
Sbjct: 4264 DPT--IRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEY 4306
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 25/223 (11%)
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD----VAILEVEINSETADVVWERDGE 1054
I + +E + V P F + L D ++ E D V +LE I T V WE +G
Sbjct: 3302 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLE-PIGDPTLRVQWEHNGH 3360
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELP----- 1106
I P N+ + L I++ D GEY C+ ++ + + VE
Sbjct: 3361 PI-PYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDA 3419
Query: 1107 PEIITRLQNQKVN--KGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
P+++ +L + N +G+ E +T D V W ++G+ + ++ + T +
Sbjct: 3420 PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFV 3479
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK-----CTAILTVEEPSINFT 1199
L I +D G+Y V N K T I + PS+++T
Sbjct: 3480 SLDILYAYPEDNGDYELVVRNDKGEARSKTKITVLPRPSLDYT 3522
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P I +L + +G+ F E+ + V+W G I SN+++++ DGK+ L++
Sbjct: 4356 PHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILEL 4415
Query: 1166 YDCDLDDAGEYSCEVGNSKCTA 1187
D AGEY + N K A
Sbjct: 4416 ARVTPDSAGEYQIVIRNDKGAA 4437
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGSTVQFECQVEGYPRPQIT--WFR 545
++I+ E +E + AP FV +L +G + E QVE Q+T WF
Sbjct: 1837 QEIENREKLEAVDAEPEKTAPKFVTQLNSSLGELQEGVPIHLEAQVEPTNDNQLTVQWFH 1896
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ F+ +D VA L I F +D G + CVA+N+ G A + V
Sbjct: 1897 NGQPLANGHRFRTRHDFGYVA-LDILYAFAQDTGEWACVARNSLGEAQTIANFTV 1950
Score = 43.6 bits (98), Expect = 0.002
Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 24/247 (9%)
Query: 490 EKIDKLPVFEKPTSEEQSMA---PIFVEKLRPKH-TPDGSTVQFECQVEGY--PRPQITW 543
+KI + P EE + P FV +L +G FE Q + P+ + W
Sbjct: 2098 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 2157
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-- 601
+ + S ++ +D + +L ++ EDAG ++ V KN+ G ++ +L
Sbjct: 2158 YLNGNPLSASSR-RILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTR 2216
Query: 602 -APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD------EGSDILLE 654
A L D E + EG P + K Q + EGS LLE
Sbjct: 2217 AAILGDTQHEQSWQRIQEIEAPRAPGAEPEG--PVYEKPSFVQPLQSVGDLPEGSVALLE 2274
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
RLV + +P+ + W + + ++ IS + + C L+I V G Y+ A
Sbjct: 2275 ARLVPVNDPNLRVQWFYNDQPLMESNWISTSND----FGCVSLRIAPVYARHTGVYSCKA 2330
Query: 713 VNREGEA 719
N G A
Sbjct: 2331 WNDSGNA 2337
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/184 (20%), Positives = 68/184 (36%), Gaps = 12/184 (6%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWER-DGEIIKPKKNKYDFEKRGH-IRK 1073
P+F+ Q K + ++ + T + W++ DG +I+ KY E +
Sbjct: 305 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQ-SGGKYKIENGPDGSGR 363
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAE------VTVVELP--PEIITRLQNQKVNKGNKAT 1125
L I HD Y + R++ + + V + P PE + Q+ + G+
Sbjct: 364 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVK 423
Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
+ +WFKD I + G + L I + + + G Y C+ N
Sbjct: 424 LYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRCDATNKHG 483
Query: 1186 TAIL 1189
T L
Sbjct: 484 TTTL 487
Score = 43.2 bits (97), Expect = 0.002
Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 18/223 (8%)
Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P FV++L P +G V E QV +T W + + F + D +A
Sbjct: 1327 PAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRFVLSQDFGYIA 1386
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMTVXXXXXXXXXX 623
L I +PED GT+T V +N AG A ST ++ +D ++
Sbjct: 1387 -LNILYCYPEDNGTYTLVVRNRAGEAQSTVDINCGHTGGNFTDSFHPNSLHRIAELETPI 1445
Query: 624 XXADIL---EGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVP 676
A+ L E PT +K A V E + LE ++ I + + WLF G +
Sbjct: 1446 QRAEPLPDKEKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKA 1505
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
V +D L I + G YT+V N G A
Sbjct: 1506 SSRYRVL--NDFGFVS--LDIDYIIAEDSGKYTLVVYNSAGRA 1544
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT--ITWCKNNKPV-KALPTKSDGDTH 787
E + PQ IEPL S+ + +S +V P I W K+ +P+ + K D
Sbjct: 1986 EHDAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFG 2045
Query: 788 SITILKPKKV-KDEGVYTLKAENSEGIAETSAVITV 822
I++ V +D GVY++KA N++G AE A +TV
Sbjct: 2046 YISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTV 2081
Score = 41.5 bits (93), Expect = 0.006
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 526 TVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
TV F +V G P P +TW + +I+ +++ D L+I +V DA + V
Sbjct: 321 TVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRLIIEKVDAHDADMYMLV 380
Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMT 612
A+N G S L V S E T
Sbjct: 381 ARNDGGSFQSRFSLNVLQAKSPEAPEFT 408
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 821 TVEEPTEENA-EPPLFINRFQ-EITVKEKGTIKLVARVT-RNPVP-SITWYRNNEIISPS 876
+VE P E N+ E P F +I V E + AR+ N V ++ WY N + +
Sbjct: 914 SVERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAA 973
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
FD + L + + DSG Y VA N G++ + + EKV +++
Sbjct: 974 HRFHPMFDFGYVALDLLYAYPQ-DSGTYTLVARNELGEARSNVELVVGTEKVLYLE 1028
Score = 41.5 bits (93), Expect = 0.006
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 1285 EFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E P + +E + G VTL LV+ P EW++N ++ + + +
Sbjct: 2384 EKPQWVQGFENYENVGEGQTVTLHGLVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN 2443
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
A LTI V D+G+Y R N G A VT
Sbjct: 2444 AILTIVHVLPHDSGVYTCRAWNTQGEASTSATVT 2477
Score = 41.5 bits (93), Expect = 0.006
Identities = 53/264 (20%), Positives = 93/264 (35%), Gaps = 25/264 (9%)
Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
E+++ Q+ Q KL + + +E AP F +L+ +G +FE QV
Sbjct: 3534 ESHFKQHSQAKLQLTANDI------YNESDKRAPEFRTQLQNIGVLEGEFCRFETQVAPI 3587
Query: 537 PRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
P ++ WF+ + F+ D A L + P+D G + CVA N G
Sbjct: 3588 NDPYLKVEWFKDKKPVLLGHRFRSTLDF-GFACLDLLYALPDDTGEYHCVATNRHGQTMI 3646
Query: 595 TTELIVEAPL-----SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP------KAQ 643
+ +L + S + V ++ + P + P +
Sbjct: 3647 SAKLACQGASHVITDSQMPQGLRVSNVKKDNKNIYWSEQGGAVQPKQKQAPQFTIPLRNL 3706
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V E EC + P P + W G + + + + ++ S +I++
Sbjct: 3707 QVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDA--- 3763
Query: 704 QEGTYTVVAVNREGEASLPIVLKI 727
G +A N EGE L I
Sbjct: 3764 --GEVVAIARNTEGETISTATLDI 3785
Score = 40.7 bits (91), Expect = 0.011
Identities = 44/207 (21%), Positives = 76/207 (36%), Gaps = 6/207 (2%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A ++ PP F P++ + ++V P P + W K + V IE
Sbjct: 297 AALVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSGGKYKIE 355
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSM 744
+ L I V Y +VA N G L + + E P+ +S
Sbjct: 356 NGPD-GSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQST 414
Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITI-LKPKKVKDEGV 802
+ G+SV L + G + W K+N+P+ + + + D + T+ + +K+ G
Sbjct: 415 TLYDGDSVKLYCKAAGE-GVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGW 473
Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN 829
Y A N G + V + N
Sbjct: 474 YRCDATNKHGTTTLKGRVVVNSRQKFN 500
Score = 40.7 bits (91), Expect = 0.011
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P + I R++ Q + K T + T + ++WFKDG + SN +LT D L I
Sbjct: 1995 PLDSIDRMEFQSAHFQTKVTPQ---TDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDI 2051
Query: 1166 YDCDLDDAGEYSCEVGNSK 1184
+D+G YS + N+K
Sbjct: 2052 AHTVPEDSGVYSVKASNAK 2070
Score = 40.3 bits (90), Expect = 0.015
Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 730 GEKEPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKS 782
G +EPP + PL++ + V +GE + L QV + + I W ++ + + T
Sbjct: 1189 GPQEPPTFVVPLQADLGDVEEGEPIHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFY 1248
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
D S+ IL +D G YT +AENS G AET A I
Sbjct: 1249 DFGFVSLDILG-FYAQDAGTYTCRAENSLGQAETVATI 1285
Score = 40.3 bits (90), Expect = 0.015
Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%)
Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVV--GNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
PP+ + L S+ V +G+ AQ + +P+ ++ W N P+ A + + +
Sbjct: 2120 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 2179
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVIT----------------------VEEPT 826
L + +D G Y++ +NSEG TS ++ +E P
Sbjct: 2180 SLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTRAAILGDTQHEQSWQRIQEIEAPR 2239
Query: 827 EENAEP-------PLFINRFQEITVKEKGTIKLV-ARV--TRNPVPSITWYRNNEIISPS 876
AEP P F+ Q + +G++ L+ AR+ +P + W+ N++ + S
Sbjct: 2240 APGAEPEGPVYEKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMES 2299
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I+ + D + L I V + +G Y C A N +G + A V +
Sbjct: 2300 NWISTSNDFGCVSLRIAPVYAR-HTGVYSCKAWNDSGNAVTSANVGV 2345
Score = 39.5 bits (88), Expect = 0.026
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
Q+P PL+N+ N+ C G P+PKVTW+ +G +
Sbjct: 3695 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQ 3736
Score = 39.5 bits (88), Expect = 0.026
Identities = 21/78 (26%), Positives = 36/78 (46%)
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
++G V + P+P +W K I + K S D K A L + +V AG Y+
Sbjct: 4368 RQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQ 4427
Query: 1360 LRLENNCGHADVEMNVTI 1377
+ + N+ G A + +T+
Sbjct: 4428 IVIRNDKGAATSQAKLTL 4445
Score = 39.1 bits (87), Expect = 0.034
Identities = 58/279 (20%), Positives = 103/279 (36%), Gaps = 22/279 (7%)
Query: 490 EKIDKLPVFEKPT-SEEQSMAPIF-----VEKLRPKHTPDGSTVQFECQVEGY--PRPQI 541
E ++ + E P +E ++ AP++ ++ K +G V FE + PR Q+
Sbjct: 2624 ESWKRIQILEAPKEAEPEAPAPVYDHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQV 2683
Query: 542 TWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV- 600
W R + + + D + TL + +PED G + N G A S+ L
Sbjct: 2684 QWIRNGVPLAHGSKYAIQ-QDFGICTLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCH 2742
Query: 601 --EAPLSD---HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLE 654
+A L D S + AD PP F ++ + E E
Sbjct: 2743 GKDAILGDVQHQESWKRIQEIEAPKQKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFE 2802
Query: 655 CRLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
+ + +P I W GE + + + +D ++ I + G + VA
Sbjct: 2803 ATVEPVDDPTLTINWFLNGEPMSASSRVKMI--NDFGWV--IMDIAQTEPRDSGEWKCVA 2858
Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
N GEA ++++ E ++P +RQ E+
Sbjct: 2859 KNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEA 2897
Score = 38.7 bits (86), Expect = 0.045
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 731 EKEPPQVIEPLKSMI--VRQGESVILSAQVVGNPRPTIT--WCKNNKPVKALPTKSDGDT 786
EKE P + +PL + I V + +++ L AQV T+ W N P+KA +
Sbjct: 1455 EKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKASSRYRVLND 1514
Query: 787 HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE 823
L + +D G YTL NS G AETS V+
Sbjct: 1515 FGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1553
Score = 38.7 bits (86), Expect = 0.045
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PE T+LQN V +G FE ++ D V WFKD + + + T+D L
Sbjct: 3561 PEFRTQLQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACL 3620
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
+ DD GEY C N
Sbjct: 3621 DLLYALPDDTGEYHCVATN 3639
Score = 37.9 bits (84), Expect = 0.078
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
+P + W N I S I+ + L+I ++ + D+G+YKCVA+N G ++
Sbjct: 3348 DPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAA-DAGEYKCVATNVKGSATSV 3406
Query: 919 ARVTID----VEKVTFVKHLQKSYET-EEGKTVILECQTS 953
++ ++ ++ V+ L S E EG ++ LEC+ +
Sbjct: 3407 GKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVT 3446
Score = 37.5 bits (83), Expect = 0.10
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNN 772
E EA P + PP+ L +++G+ L QV V +PR I W N
Sbjct: 3164 EIEAPRPAREDAPDADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNG 3223
Query: 773 KPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+PV K+ D + + L P + +D G +T +A N G E S + V
Sbjct: 3224 QPVNHTNRMKAIHDFGFVVLQLTPAEPQDSGTWTCRATNQHGSDEVSTELKV 3275
Score = 37.1 bits (82), Expect = 0.14
Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 1107 PEIITRLQNQ-KVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
P I+ LQ Q + +G A + + T V W KDG I SN ++ D
Sbjct: 2913 PAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHSNRYKMVHDFGFAV 2972
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIP 1221
L I DAGEY+ V N+ A S +F + IL P N VEI
Sbjct: 2973 LDILHLLKHDAGEYTFRVSNNSGEA-----STSTSFEVSESSGLILQPQNEQKAKAVEIL 3027
Query: 1222 DETL 1225
++ L
Sbjct: 3028 EDNL 3031
Score = 36.7 bits (81), Expect = 0.18
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 36/249 (14%)
Query: 709 TVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPT 765
T+ V++ + P+ L+ + K P+ L+S + +G+S L + V +P
Sbjct: 509 TLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLR 568
Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
I W N K + A + T +D ++ I P V D+G YT+ A N G A SA I V
Sbjct: 569 IAWLLNGKGILASSRIVTFTDFGIAALEI-NPVNVFDQGEYTVVAVNPLGEARVSANIAV 627
Query: 823 --------------------------EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
+ P + + P F + + V E I L ++
Sbjct: 628 IGHGSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKL 687
Query: 857 T--RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
T +P + W + + ++ Q L I S DSG Y C A N G+
Sbjct: 688 TPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSN-DSGLYSCRAFNKLGE 746
Query: 915 SSHGARVTI 923
S + A + I
Sbjct: 747 SENQATIII 755
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P + L++Q+V +G + E +LT D V W DG+E+ ++ + T+ L
Sbjct: 664 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 723
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
I +D+G YSC N
Sbjct: 724 DIPQTSSNDSGLYSCRAFN 742
Score = 36.3 bits (80), Expect = 0.24
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDGD 785
+PP E L ++G+S+ L ++ V +P +TW +N +P+ + +P ++ D
Sbjct: 1723 QPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPLPEASRFMPARNF-D 1781
Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++ IL +D GVYT KA ++ G A TS +
Sbjct: 1782 YVNLDILALYG-EDSGVYTCKAVSAFGEAATSCTV 1815
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P + W+K+G L N + +TT + I S Y+++ASN G + V+
Sbjct: 2019 PNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQ 2078
Query: 1660 LKV 1662
L V
Sbjct: 2079 LTV 2081
Score = 36.3 bits (80), Expect = 0.24
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
+P ++ A P F + + V E + VT P P +TW+ N NF
Sbjct: 3690 QPKQKQA--PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNF 3747
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
DG + + + D+G+ +A N+ G++ A + I
Sbjct: 3748 DG--LHYLTVSKSRISDAGEVVAIARNTEGETISTATLDI 3785
Score = 35.9 bits (79), Expect = 0.32
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870
+ E E+P E+ + P FI I E + +VT P+ I W+++
Sbjct: 1971 VLEAPRAAAPEKPDAEH-DAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDG 2029
Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ + S D I L I + E DSG Y ASN+ G + A++T+
Sbjct: 2030 QPLMNSNRFKLTTDFGYISLDIAHTVPE-DSGVYSVKASNAKGDAEVQAQLTV 2081
Score = 34.7 bits (76), Expect = 0.73
Identities = 17/66 (25%), Positives = 31/66 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P V+W +GN+L ++ +Y T + + I + + S Y+ A N G S + T
Sbjct: 693 PDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSNDSGLYSCRAFNKLGESENQAT 752
Query: 1660 LKVYDK 1665
+ + K
Sbjct: 753 IIIVPK 758
Score = 34.3 bits (75), Expect = 0.97
Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
+P F L+ EV E LE + IN VVW DG + P +KY
Sbjct: 663 LPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFA 721
Query: 1073 KLYIRNTSVHDEGEYSC 1089
L I TS +D G YSC
Sbjct: 722 SLDIPQTSSNDSGLYSC 738
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 1013 KETIPEFIRKLQDFEVKEK-DVAILEVEI---NSETADVVWERDGEIIKPKKNKYDFEKR 1068
++ P+F+ ++Q F +++ + E I N T V W +DG+ + P N+ +
Sbjct: 785 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNANRIQIFQN 843
Query: 1069 GHIRKLYIRNTSVHDEGEYSCIL 1091
+ L + T D G Y+C+L
Sbjct: 844 FGVVSLSLHPTYPEDAGVYTCVL 866
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P +V W K+G + + Y + +V+ I L + + +YT SN +G +S +
Sbjct: 2943 PSIKVEWLKDGQPIFHSNRYKMVHDFGFAVLDILHLLKHDAGEYTFRVSNNSGEASTSTS 3002
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIE 1686
+V S+ G ++ + +++ +E
Sbjct: 3003 FEV----SESSGLILQPQNEQKAKAVE 3025
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASL 1345
PK + ++ G L + Y PN W++N K I D A+L
Sbjct: 536 PKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILASSRIVTFTDFGIAAL 595
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
I V D G Y + N G A V N+ ++
Sbjct: 596 EINPVNVFDQGEYTVVAVNPLGEARVSANIAVI 628
Score = 33.1 bits (72), Expect = 2.2
Identities = 47/216 (21%), Positives = 81/216 (37%), Gaps = 12/216 (5%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P F LR + +G + E ++ P ++ W + PS D A+
Sbjct: 664 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFAS 722
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXA 626
L I + D+G ++C A N G + + +I+ P SD E A
Sbjct: 723 LDIPQTSSNDSGLYSCRAFNKLGESENQATIII-VPKSDLQQFEQHRQLDVEDVREIQFA 781
Query: 627 DILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVA 683
+ + P F + + + + E E R+ I +P ++WL G+ + P+ N
Sbjct: 782 HSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNAN---R 837
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I+ + L + G YT V N G+A
Sbjct: 838 IQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 873
Score = 33.1 bits (72), Expect = 2.2
Identities = 16/47 (34%), Positives = 25/47 (53%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
V W KDG + +N IQ+ + L ++ +DAG Y+C + NS
Sbjct: 823 VSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNS 869
Score = 33.1 bits (72), Expect = 2.2
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 1106 PPEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
PP+ +T+L + V +G + FE I + V+W+ +G+ + S+ L D
Sbjct: 2120 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 2179
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK 1184
L + +DAGEYS V NS+
Sbjct: 2180 SLDLQYTLGEDAGEYSVVVKNSE 2202
Score = 32.7 bits (71), Expect = 3.0
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 7/116 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKN 771
R+ EA P + + E P ++ L+ + +G S L Q V +P + W K+
Sbjct: 2893 RQIEAGKPAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKD 2952
Query: 772 NKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
+P+ D + IL K D G YT + N+ G A TS V E
Sbjct: 2953 GQPIFHSNRYKMVHDFGFAVLDILHLLK-HDAGEYTFRVSNNSGEASTSTSFEVSE 3007
Score = 32.3 bits (70), Expect = 3.9
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 735 PQVIEPLKSMIVRQGES--VILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITI 791
P+ + L + + + E+ V L A V +P I W N +P+ K+ + I +
Sbjct: 1061 PKFLNDLPDIQLNEHENIHVDLRATPVNDPTMVIEWFVNGRPLLTGSRVKTLNEFGFIAL 1120
Query: 792 -LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+K +D G Y+++A N G A VITV
Sbjct: 1121 DIKGAIAEDSGTYSVRASNLLGEAIRQCVITV 1152
Score = 32.3 bits (70), Expect = 3.9
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTIT--WCKN 771
+E EA P ++ +PP ++ L I +G++V L AQV ++T W N
Sbjct: 1307 QEIEAPKPAPQEVPDLPHQPPAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVN 1366
Query: 772 NKPV-KA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
+P+ KA D ++ IL +D G YTL N G A+++ I
Sbjct: 1367 GQPLMKAHRFVLSQDFGYIALNILYCYP-EDNGTYTLVVRNRAGEAQSTVDI 1417
Score = 31.9 bits (69), Expect = 5.2
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIA 814
Q + +P ++W K+ +P+ + L P +D GVYT NS G A
Sbjct: 814 QPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 873
Query: 815 ETSAVIT 821
++SA +T
Sbjct: 874 QSSAELT 880
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
+A ++G P P V W G + I+ K +++ + + + +Y I N G
Sbjct: 4376 SAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQIVIRNDKG 4435
Query: 1653 --TSSVEVTL 1660
TS ++TL
Sbjct: 4436 AATSQAKLTL 4445
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/66 (24%), Positives = 29/66 (43%)
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
Q P +W + + + K + D SL I D+G+Y ++ N G A+V
Sbjct: 2016 QTDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEV 2075
Query: 1372 EMNVTI 1377
+ +T+
Sbjct: 2076 QAQLTV 2081
Score = 31.1 bits (67), Expect = 9.0
Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ G P P+V W+ NGN+ + + + + + + + + S + + A NT G +
Sbjct: 3720 VTGYPRPKVTWFINGNQCLHGHRFKLNF-DGLHYLTVSKSRISDAGEVVAIARNTEGETI 3778
Query: 1656 VEVTLKVY 1663
TL ++
Sbjct: 3779 STATLDIF 3786
>AY819766-1|AAV69856.1| 4250|Caenorhabditis elegans kettin protein.
Length = 4250
Score = 113 bits (271), Expect = 2e-24
Identities = 113/458 (24%), Positives = 188/458 (41%), Gaps = 64/458 (13%)
Query: 500 KPTSEEQSMA--PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
+PT QS P ++L+P G +F + G ++TW + IK +
Sbjct: 3821 QPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTL 3880
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ N ++L I + AG +T +NAAG S L V P +
Sbjct: 3881 ITTTPTN-SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTT------------ 3927
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
+G P FS + + + C++ P+P I W G+ + D
Sbjct: 3928 ------------QGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPND 3975
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---KTGEK-- 732
+ V E + LK +N+ G Y +VA N GEA L + KTG+
Sbjct: 3976 DRFQVVEEGGAYK----LKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAE 4031
Query: 733 -----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
E P+ ++ ++V +G+ SAQ G P PTI W +NN+PVK +
Sbjct: 4032 EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSK 4091
Query: 788 SITILKPKKVKDEGV--YTLKAENSEGIAETSA--VIT------------------VEEP 825
IL+ ++E V Y ++A N G A + A V+T +
Sbjct: 4092 GEAILRISAARNEDVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSS 4151
Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
+ A+ P FI + +I+ ++ T+K A V NP P++ W + IS S + + DG
Sbjct: 4152 DKAAADSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDG 4211
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ L + V + +G+Y+ V N G ++ A++T+
Sbjct: 4212 KRAILELARVTPD-SAGEYQIVIRNDKGAATSQAKLTL 4248
Score = 84.2 bits (199), Expect = 9e-16
Identities = 64/272 (23%), Positives = 121/272 (44%), Gaps = 18/272 (6%)
Query: 722 PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
P KI ++ PP + + LK + G++ + G +TW K+ K +K+
Sbjct: 3820 PQPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRT 3879
Query: 782 SDGDTHSITILKPKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
T + + L ++++ G YT++ EN+ G E+ A +TV PT + P F R
Sbjct: 3880 LITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPD-FSARL 3938
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ +++ G + ++ P P+I W+++ + + + +G +L +N+ S
Sbjct: 3939 NDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIIS-T 3997
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE------------TEEGKTVI 947
D+G Y+ VA N G++ AR+ ++++K YE +EGK
Sbjct: 3998 DAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQ 4057
Query: 948 LECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977
Q S + +WY N + + D EI Q
Sbjct: 4058 FSAQFSGFPDPTIRWYRNNEPVKHADGYEISQ 4089
Score = 76.6 bits (180), Expect = 2e-13
Identities = 53/195 (27%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSI 789
PPQ + +S+ + E+V SA+VVG P P++TW K++ V ++ D
Sbjct: 66 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGR 125
Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
I++ D +Y L A N G ++ + V + ++ E P F +FQ T+ + +
Sbjct: 126 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQ--AKSPEAPEFTGKFQSTTLYDGDS 183
Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
+KL + V S W+++NE IS + + G L I N + + G Y+C A+
Sbjct: 184 VKLYCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMK-EGGWYRCDAT 241
Query: 910 NSAGKSSHGARVTID 924
N G ++ RV ++
Sbjct: 242 NKHGTTTLKGRVVVN 256
Score = 66.1 bits (154), Expect = 3e-10
Identities = 119/539 (22%), Positives = 206/539 (38%), Gaps = 81/539 (15%)
Query: 474 LMDENNYTQYLQKKLN-EKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFEC 531
L+ + ++ LQK E IDK + P E + P +V+ ++ +G TV
Sbjct: 2113 LLLDTSHPASLQKIQELEAIDKYARLDAPEREYEK--PQWVQGFENYENVGEGQTVTLHG 2170
Query: 532 QVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
VE G P ++ W ++ + F+ Y+ N A L I V P D+G +TC A N
Sbjct: 2171 LVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN-AILTIVHVLPHDSGVYTCRAWNTQ 2229
Query: 590 GFASSTTELIV---EAPLSDHGSEMT---VXXXXXXXXXXXXADILEGIPPTF-SKKPKA 642
G AS++ + E L D ++ + +I++ P F ++ A
Sbjct: 2230 GEASTSATVTTAGYEKILYDSQHPVSWERIQELEAPKIVEEIEEIVQKEKPNFLTQLESA 2289
Query: 643 QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDE-----------NISVAIESDMH 689
+ V EG + LE +P+ + W G+ + + + ++ ++ H
Sbjct: 2290 ENVPEGVPLHLESTFQPARDPELKVVWQKNGQPLGASQLVQTKHELGWATLDISSANEDH 2349
Query: 690 MYCSVLKITNVKKFQ--------EGTYTVVAVNREGEASLPIVLKIKTGEKEP------- 734
L ITN + GT ++ R E+ I + E EP
Sbjct: 2350 NGVYTLTITNSEGEAVSTASIRVAGTGPILGNTRHEESWKRIQILEAPKEAEPEAPAPVY 2409
Query: 735 --PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
P + + +G+ V A + V +PR + W +N P+ + I
Sbjct: 2410 DHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQVQWIRNGVPLAHGSKYAIQQDFGIC 2469
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVI----------------------TVEEPT 826
L +DEGVY L+ N EG A +SA + +E P
Sbjct: 2470 TLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCHGKDAILGDVQHQESWKRIQEIEAPK 2529
Query: 827 EENAE-------PPLFINRFQ---EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
++ E PP FI + + + + +P +I W+ N E +S S
Sbjct: 2530 QKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSAS 2589
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
+ D + + I + DSG++KCVA N+AG++ A + + ++V LQ
Sbjct: 2590 SRVKMINDFGWVIMDIAQTEPR-DSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQ 2647
Score = 64.1 bits (149), Expect = 1e-09
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 23/248 (9%)
Query: 500 KPTSEEQS-MAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQ 554
KP+ ++ + P+F ++L P +G +V +C V+ P +I WF +
Sbjct: 1343 KPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGS 1402
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDH- 607
+ +D V L + PED GT+TC A N G +TT++ +E L H
Sbjct: 1403 RIRTIHDFGYVG-LEFLHIHPEDTGTYTCKATNLIG--EATTDIFLECKPRRNIYLDTHH 1459
Query: 608 -GSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD- 664
S + L PPTF++ + EG I LECRL+ + +P
Sbjct: 1460 ESSWQKIQEIENRVDEREPTPELTFQPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTM 1519
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+ W G+ + A D Y + L I + G YT AV+ GEA+
Sbjct: 1520 RVTWTRNGQPLPEASRFMPARNFD---YVN-LDILALYGEDSGVYTCKAVSAFGEAATSC 1575
Query: 724 VLKIKTGE 731
+K G+
Sbjct: 1576 TVKCAAGK 1583
Score = 63.3 bits (147), Expect = 2e-09
Identities = 78/409 (19%), Positives = 161/409 (39%), Gaps = 29/409 (7%)
Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP-QPNDEWIVNSKIIK 1329
LD + ++K++ + P + D E ++K ++ + + Q P QP +E IV+ ++
Sbjct: 3718 LDVPARDQVKLKTAK-PTRGKDLEAGEKVKLKTEKAKIKEIQQKPEQPKEEPIVHKDAVQ 3776
Query: 1330 KCKHTKPSIDSKSASLTI---KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
P K T+ K ++ T A + + E + + + P
Sbjct: 3777 LKTQQLPKTGIKGDHFTVDREKDLKETPAVVKPVIEETRISNKPQPTKIGQSKQAPPTIS 3836
Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
+ + E G + + + ++ + +EI +T + ++ T T +S+ +
Sbjct: 3837 QQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKST-FRTLITTTPTNSSLHIGRL 3895
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKET-KIQSPTVEKPLKNITTEPNEDIELTCI 1504
+S+ Y V + + E+ V T + ++P L ++ + N E +C
Sbjct: 3896 ENSHAGE-YTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQ 3954
Query: 1505 FGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVE 1560
GG P+P + W++DG+ L + E Y+ +A N GE
Sbjct: 3955 IGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEAR 4014
Query: 1561 TSCVVGIQ--------------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
+ + + P T + I G ++ +A G P P + W
Sbjct: 4015 CKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQF--SAQFSGFPDPTIRW 4072
Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
Y+N +++ Y I+ + +++RI + ++Y +EASN AG +S
Sbjct: 4073 YRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKAS 4121
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/319 (22%), Positives = 119/319 (37%), Gaps = 27/319 (8%)
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
+ PP I +L+ + G A F IE + V W KDG EI+ + +T
Sbjct: 3830 QAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSS 3889
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCT----AILTVEEPSI-----NFTLRLPEFILVPANTD 1213
L I + AGEY+ + N+ T A LTV P+ +F+ RL + + + N
Sbjct: 3890 LHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLND-LRIQQNGP 3948
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271
A + +I E + W+K + + ++F ++ + L D Y V
Sbjct: 3949 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4008
Query: 1272 ---DAKSTTKLKVEVV-------EFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+A+ +L V + E P P+ + + G + FP P
Sbjct: 4009 GVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDP 4068
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W N++ +K + S A L I N D YK+ N G A N+ +
Sbjct: 4069 TIRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVL 4128
Query: 1378 LDKPSPPGKPNILEIDSSS 1396
+ K I S+S
Sbjct: 4129 TPRSGRIAKSTISRGGSAS 4147
Score = 62.1 bits (144), Expect = 4e-09
Identities = 83/338 (24%), Positives = 135/338 (39%), Gaps = 32/338 (9%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
P F L P +G ECQV PR I WF + + + +D V
Sbjct: 2945 PKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIHDFGFVV 3004
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---------PLSDHGSEMT-VXXX 616
L + P+D+GT+TC A N G +TEL V ++ +T +
Sbjct: 3005 -LQLTPAEPQDSGTWTCRATNQHGSDEVSTELKVVGGGGVSYEWQSTAERKERITELEDW 3063
Query: 617 XXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
++ P+FS+ ++E C L I +P + W G
Sbjct: 3064 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHP 3123
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK- 732
I IS E + + L I ++ G Y VA N +G A+ + +++ +
Sbjct: 3124 IPYSNRISCTNEFGV----ATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQI 3179
Query: 733 EPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDG 784
+ PQV++ L + + +G+S+ L +V + +PR + W +N P+ + PT G
Sbjct: 3180 DAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFG 3239
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S+ IL +D G Y L N +G A + ITV
Sbjct: 3240 FV-SLDILYAYP-EDNGDYELVVRNDKGEARSKTKITV 3275
Score = 60.1 bits (139), Expect = 2e-08
Identities = 57/222 (25%), Positives = 91/222 (40%), Gaps = 17/222 (7%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F K + DG +V+ C+ G WF+ I + + + N TL
Sbjct: 166 APEFTGKFQSTTLYDGDSVKLYCKAAG-EGVSFKWFKDNEPISSGGSYAVD-NKGNETTL 223
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS---EM-TVXXXXXXXXXXX 624
I ++ G + C A N G + ++V + +G EM T+
Sbjct: 224 HINNATMKEGGWYRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREMITLRKVDKVERSRT 283
Query: 625 XADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPD 677
+ L+ + P F ++Q + EG LE + + +P+ IAWL G+ I+
Sbjct: 284 PVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILAS 343
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I + + + L+I V F +G YTVVAVN GEA
Sbjct: 344 SRIVTFTDFGI----AALEINPVNVFDQGEYTVVAVNPLGEA 381
Score = 55.6 bits (128), Expect = 4e-07
Identities = 51/192 (26%), Positives = 81/192 (42%), Gaps = 15/192 (7%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDG 885
NA PP F+ Q + K T+ A+V P PS+TW +++ + S I DG
Sbjct: 63 NARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDG 122
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV------EKVTFVKHLQKSYE 939
L+I VD+ D+ Y VA N G S +R +++V E F Q S
Sbjct: 123 SG-RLIIEKVDAH-DADMYMLVARNDGG--SFQSRFSLNVLQAKSPEAPEFTGKFQ-STT 177
Query: 940 TEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
+G +V L C+ + VS KW+ + + IS + +G + G +
Sbjct: 178 LYDGDSVKLYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYR 237
Query: 999 CIVKDQETSTML 1010
C ++ +T L
Sbjct: 238 CDATNKHGTTTL 249
Score = 54.8 bits (126), Expect = 6e-07
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+Q AP F LR + +FEC V GYPRP++TWF F++ +D +
Sbjct: 3454 KQKQAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLH 3513
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
T+ + DAG +A+N G ST L
Sbjct: 3514 YLTVSKSRI--SDAGEVVAIARNTEGETISTATL 3545
Score = 54.8 bits (126), Expect = 6e-07
Identities = 53/230 (23%), Positives = 90/230 (39%), Gaps = 19/230 (8%)
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
+ E IS+ + T+ I ++K PT+ + LK + E + + F G KVTW
Sbjct: 3811 IEETRISNKPQPTK----IGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTW 3866
Query: 1516 YRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
+DGK++K T T Y N G VE+ + +
Sbjct: 3867 LKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPT 3926
Query: 1569 ---QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
+ P + D++ + E+ + I G P P + W+K+G L ND + + +
Sbjct: 3927 TQGKAPDFSARLNDLRIQQNGPAEF--SCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEG 3984
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSK--PEGP 1672
++ + + + Y I A N G + + L V K K EGP
Sbjct: 3985 GAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4034
Score = 53.2 bits (122), Expect = 2e-06
Identities = 56/223 (25%), Positives = 85/223 (38%), Gaps = 17/223 (7%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P F+++L P + FE VE P +T WF + S +M +D
Sbjct: 2543 PRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMI-NDFGWV 2601
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTT-------ELIVEAPLSDHGSEMTVXXXXXX 619
+ I + P D+G + CVAKNAAG A ST E+I++ L +
Sbjct: 2602 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEAGK 2661
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVPD 677
D P + ++EG L+ + + +P I WL G+ I
Sbjct: 2662 PAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHS 2721
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
+ + +VL I ++ K G YT N GEAS
Sbjct: 2722 NRYKMVHDFGF----AVLDILHLLKHDAGEYTFRVSNNSGEAS 2760
Score = 52.8 bits (121), Expect = 3e-06
Identities = 59/241 (24%), Positives = 93/241 (38%), Gaps = 17/241 (7%)
Query: 491 KIDKLPVFEKPTSEEQSMA-----PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITW 543
K+DK+ P ++ Q ++ P F L+ + +G + + E + P +I W
Sbjct: 274 KVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAW 333
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
I S + + D +A L I V D G +T VA N G A + + V
Sbjct: 334 LLNGKGILASSRI-VTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGEARVSANIAVIGH 392
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIP---PTFSKKPKAQYVDEGSDILLECRLVAI 660
S + + A G P F ++Q V EG I LE +L I
Sbjct: 393 GSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKLTPI 452
Query: 661 PEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+PD + WL G E+ ++ + H + S L I G Y+ A N+ GE
Sbjct: 453 NDPDLRVVWLLDGNELPSNDKYRQTLS---HGFAS-LDIPQTSSNDSGLYSCRAFNKLGE 508
Query: 719 A 719
+
Sbjct: 509 S 509
Score = 52.0 bits (119), Expect = 5e-06
Identities = 64/265 (24%), Positives = 102/265 (38%), Gaps = 22/265 (8%)
Query: 470 PAQYLMDENNYTQYLQK-KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGST 526
PA ++ + + + L K E ++K E Q P FV L+ +G
Sbjct: 916 PAGQILSDTQHQESLGKINYLENLNKYGRVEIEDKGPQE-PPTFVVPLQADLGDVEEGEP 974
Query: 527 VQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
+ ECQV +I W R + F+ +YD V+ L I + +DAGT+TC
Sbjct: 975 IHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFYDFGFVS-LDILGFYAQDAGTYTCR 1033
Query: 585 AKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
A+N+ G A + + + + S + L PP F K
Sbjct: 1034 AENSLGQAETVATIRCAPKDAILGAVQHPRSYARIQEIEAPKPAPQEVPDLPHQPPAFVK 1093
Query: 639 K--PKAQYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSV 694
+ P Q + EG ++ LE ++ + + WL G+ ++ + D
Sbjct: 1094 QLGPAIQCM-EGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRF--VLSQDFGYI--A 1148
Query: 695 LKITNVKKFQEGTYTVVAVNREGEA 719
L I GTYT+V NR GEA
Sbjct: 1149 LNILYCYPEDNGTYTLVVRNRAGEA 1173
Score = 51.6 bits (118), Expect = 6e-06
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 1191 VEEPSINFTLRLPEF-ILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISD 1247
V+ P+ +F+ L + L A+ A++ V P D TL V W I + + + ++
Sbjct: 3076 VDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNE 3135
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP-----PKIVDY--EREYRI 1299
TL+I+ D EY CV + K S T + VE P++V + I
Sbjct: 3136 FGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENI 3195
Query: 1300 KRGSDVTLLVDYQAFPQP--NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
G + L P + EW+ N + + KP+ + SL I D G
Sbjct: 3196 LEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFVSLDILYAYPEDNGD 3255
Query: 1358 YKLRLENNCGHADVEMNVTILDKPS 1382
Y+L + N+ G A + +T+L +PS
Sbjct: 3256 YELVVRNDKGEARSKTKITVLPRPS 3280
Score = 50.8 bits (116), Expect = 1e-05
Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 23/273 (8%)
Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR-PKHTPDGSTVQFECQ 532
L +N + L + + + P E+ E + P+F+E L P T +G F +
Sbjct: 2775 LQPQNEQKAKAVEILEDNLRRRP--EEIEQELKEATPVFIEPLSAPVETEEGGRAHFTAR 2832
Query: 533 VEGYP--RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
E + Q+ W+ +K + + L I +PED G + C A N G
Sbjct: 2833 YEPVNDNQLQVQWYHDGRPLKNGSRIKTI-NSFGYVVLEISPTYPEDNGEYICRAVNRVG 2891
Query: 591 FASSTTEL-------IVEA---PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKK 639
A ++T+L I+ A P + + A + PP F S
Sbjct: 2892 EAVTSTKLTCTPKEGIISATQLPERMANAGRRIAEIEAPRPAREDAPDADHGPPKFTSAL 2951
Query: 640 PKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
+ EG LEC++ + +P I W G+ + N + +++ VL++
Sbjct: 2952 AGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPV----NHTNRMKAIHDFGFVVLQL 3007
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730
T + GT+T A N+ G + LK+ G
Sbjct: 3008 TPAEPQDSGTWTCRATNQHGSDEVSTELKVVGG 3040
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816
+G+P + W N P+ S + + L K + D G Y A N +G A +
Sbjct: 3108 IGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATS 3167
Query: 817 SAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVT--RNPVPSITWYRNNEII 873
I VE T+ +A P + + + E +I L RVT +P + W RN +
Sbjct: 3168 VGKIAVESSTQIDA-PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPL 3226
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ F+ + L I E D+GDY+ V N G++ ++T+
Sbjct: 3227 PEASRFKPTFEFGFVSLDILYAYPE-DNGDYELVVRNDKGEARSKTKITV 3275
Score = 48.4 bits (110), Expect = 6e-05
Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 20/243 (8%)
Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
E+P AP F +L K + V FE ++ + + W+ + +
Sbjct: 678 ERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAAHR 737
Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP----LSDHGSE- 610
F +D VA L + +P+D+GT+T VA+N G A S EL+V L H E
Sbjct: 738 FHPMFDFGYVA-LDLLYAYPQDSGTYTLVARNELGEARSNVELVVGTEKVLYLEPHHPEG 796
Query: 611 MTVXXXXXXXXXXXXADI----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD-- 664
+ A++ + P + P Q ++E +I ++ R + +P
Sbjct: 797 LERIKELEQDRRQGIAEVEDRTCDAAPKFLNDLPDIQ-LNEHENIHVDLRATPVNDPTMV 855
Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
I W G ++ + E L I GTY+V A N GEA V
Sbjct: 856 IEWFVNGRPLLTGSRVKTLNEFGF----IALDIKGAIAEDSGTYSVRASNLLGEAIRQCV 911
Query: 725 LKI 727
+ +
Sbjct: 912 ITV 914
Score = 46.4 bits (105), Expect = 2e-04
Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 506 QSMAPIFVEKLRPKHTPDG-STVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDD 562
Q + P F+ +++P H FE +++ P +++W + + + Q++ +
Sbjct: 547 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIF-QN 605
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
V +L + +PEDAG +TCV N+ G A S+ EL
Sbjct: 606 FGVVSLSLHPTYPEDAGVYTCVLFNSHGQAQSSAEL 641
Score = 46.0 bits (104), Expect = 3e-04
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 11/157 (7%)
Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQVV--GNPRPTITWCKNNKPVKA---LPTKSDGDT 786
E P ++PL+S+ + +G +L A++V +P + W N++P+ + T +D
Sbjct: 2013 EKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMESNWISTSNDFGC 2072
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITV 844
S+ I P + GVY+ KA N G A TSA + V+ E + P + + QE+
Sbjct: 2073 VSLRIA-PVYARHTGVYSCKAWNDSGNAVTSANVGVQGSEGLLLDTSHPASLQKIQELEA 2131
Query: 845 KEKGTIKLVARVTRNPVPS-ITWYRNNEIISPSETIT 880
+K +L A P + + N E + +T+T
Sbjct: 2132 IDK-YARLDAPEREYEKPQWVQGFENYENVGEGQTVT 2167
Score = 46.0 bits (104), Expect = 3e-04
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L+++NVKK + Y + +G A P +K+ PQ PL+++ V + +
Sbjct: 3430 LRVSNVKKDNKNIYW----SEQGGAVQP-------KQKQAPQFTIPLRNLQVTENQPARF 3478
Query: 755 SAQVVGNPRPTITWCKN-NKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENSEG 812
V G PRP +TW N N+ + K + D H +T+ K ++ D G A N+EG
Sbjct: 3479 ECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSK-SRISDAGEVVAIARNTEG 3537
Query: 813 IAETSAVITV 822
++A + +
Sbjct: 3538 ETISTATLDI 3547
Score = 45.6 bits (103), Expect = 4e-04
Identities = 55/231 (23%), Positives = 89/231 (38%), Gaps = 18/231 (7%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDF 556
EKP +E AP F+E L + + F+ +V + P +I WF+ + S F
Sbjct: 1743 EKPDAEHD--APQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRF 1800
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMT- 612
++ D ++ L I PED+G ++ A NA G A +L V L D E +
Sbjct: 1801 KLTTDFGYIS-LDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTVTGNAVILGDTQHEQSW 1859
Query: 613 ---VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAW 667
D+ G P ++ V EG E + + +P + W
Sbjct: 1860 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 1919
Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
G + + + +D + L+ T + G Y+VV N EGE
Sbjct: 1920 YLNGNPL--SASSRRILRNDFGLVSLDLQYTLGE--DAGEYSVVVKNSEGE 1966
Score = 44.8 bits (101), Expect = 7e-04
Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 17/197 (8%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE- 601
W +K S +++ +D +L I + ED+G +T V N+AG A ++ E V+
Sbjct: 1258 WLFNGNPLKASSRYRVL-NDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVDR 1316
Query: 602 --APLSD--HGSEM-TVXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLE 654
+ LSD H + + D PP F+++ + + EG + ++
Sbjct: 1317 LKSILSDTAHPESLRRIREMEQLQPAKPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMD 1376
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVV 711
C + I +P I W G ++ I +H + V L+ ++ GTYT
Sbjct: 1377 CVVQPINDPSLRIEWFHDGRPLMFGSRIRT-----IHDFGYVGLEFLHIHPEDTGTYTCK 1431
Query: 712 AVNREGEASLPIVLKIK 728
A N GEA+ I L+ K
Sbjct: 1432 ATNLIGEATTDIFLECK 1448
Score = 44.8 bits (101), Expect = 7e-04
Identities = 63/285 (22%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
K+ P ++L+ + + A +E + V W +DG+ IK +
Sbjct: 3829 KQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTN- 3887
Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE-----LPPEIITRLQNQKVNKGN 1122
L+I GEY+ L + + T E +TV P+ RL + ++ +
Sbjct: 3888 SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNG 3947
Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
A F ++ + ++WFKDG + + Q+ +G KLK + DAG Y
Sbjct: 3948 PAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAK 4007
Query: 1179 -EVGNSKCTAILTV----------EEP---SINFTLRLPEFILVPANTDAYLTVE---IP 1221
VG ++C A L V E P + FT ++ + I+V A + + P
Sbjct: 4008 NGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQI-QPIVVDEGKGAQFSAQFSGFP 4066
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
D T + WY+ ++ + + + + L I +D EY
Sbjct: 4067 DPT--IRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEY 4109
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 25/223 (11%)
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD----VAILEVEINSETADVVWERDGE 1054
I + +E + V P F + L D ++ E D V +LE I T V WE +G
Sbjct: 3064 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLE-PIGDPTLRVQWEHNGH 3122
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELP----- 1106
I P N+ + L I++ D GEY C+ ++ + + VE
Sbjct: 3123 PI-PYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDA 3181
Query: 1107 PEIITRLQNQKVN--KGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
P+++ +L + N +G+ E +T D V W ++G+ + ++ + T +
Sbjct: 3182 PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFV 3241
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK-----CTAILTVEEPSINFT 1199
L I +D G+Y V N K T I + PS+++T
Sbjct: 3242 SLDILYAYPEDNGDYELVVRNDKGEARSKTKITVLPRPSLDYT 3284
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P I +L + +G+ F E+ + V+W G I SN+++++ DGK+ L++
Sbjct: 4159 PHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILEL 4218
Query: 1166 YDCDLDDAGEYSCEVGNSKCTA 1187
D AGEY + N K A
Sbjct: 4219 ARVTPDSAGEYQIVIRNDKGAA 4240
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGSTVQFECQVEGYPRPQIT--WFR 545
++I+ E +E + AP FV +L +G + E QVE Q+T WF
Sbjct: 1599 QEIENREKLEAVDAEPEKTAPKFVTQLNSSLGELQEGVPIHLEAQVEPTNDNQLTVQWFH 1658
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ F+ +D VA L I F +D G + CVA+N+ G A + V
Sbjct: 1659 NGQPLANGHRFRTRHDFGYVA-LDILYAFAQDTGEWACVARNSLGEAQTIANFTV 1712
Score = 43.6 bits (98), Expect = 0.002
Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 24/247 (9%)
Query: 490 EKIDKLPVFEKPTSEEQSMA---PIFVEKLRPKH-TPDGSTVQFECQVEGY--PRPQITW 543
+KI + P EE + P FV +L +G FE Q + P+ + W
Sbjct: 1860 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 1919
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-- 601
+ + S ++ +D + +L ++ EDAG ++ V KN+ G ++ +L
Sbjct: 1920 YLNGNPLSASSR-RILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTR 1978
Query: 602 -APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD------EGSDILLE 654
A L D E + EG P + K Q + EGS LLE
Sbjct: 1979 AAILGDTQHEQSWQRIQEIEAPRAPGAEPEG--PVYEKPSFVQPLQSVGDLPEGSVALLE 2036
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
RLV + +P+ + W + + ++ IS + + C L+I V G Y+ A
Sbjct: 2037 ARLVPVNDPNLRVQWFYNDQPLMESNWISTSND----FGCVSLRIAPVYARHTGVYSCKA 2092
Query: 713 VNREGEA 719
N G A
Sbjct: 2093 WNDSGNA 2099
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/184 (20%), Positives = 68/184 (36%), Gaps = 12/184 (6%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWER-DGEIIKPKKNKYDFEKRGH-IRK 1073
P+F+ Q K + ++ + T + W++ DG +I+ KY E +
Sbjct: 67 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQ-SGGKYKIENGPDGSGR 125
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAE------VTVVELP--PEIITRLQNQKVNKGNKAT 1125
L I HD Y + R++ + + V + P PE + Q+ + G+
Sbjct: 126 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVK 185
Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
+ +WFKD I + G + L I + + + G Y C+ N
Sbjct: 186 LYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRCDATNKHG 245
Query: 1186 TAIL 1189
T L
Sbjct: 246 TTTL 249
Score = 43.2 bits (97), Expect = 0.002
Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 18/223 (8%)
Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P FV++L P +G V E QV +T W + + F + D +A
Sbjct: 1089 PAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRFVLSQDFGYIA 1148
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMTVXXXXXXXXXX 623
L I +PED GT+T V +N AG A ST ++ +D ++
Sbjct: 1149 -LNILYCYPEDNGTYTLVVRNRAGEAQSTVDINCGHTGGNFTDSFHPNSLHRIAELETPI 1207
Query: 624 XXADIL---EGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVP 676
A+ L E PT +K A V E + LE ++ I + + WLF G +
Sbjct: 1208 QRAEPLPDKEKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKA 1267
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
V +D L I + G YT+V N G A
Sbjct: 1268 SSRYRVL--NDFGFVS--LDIDYIIAEDSGKYTLVVYNSAGRA 1306
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT--ITWCKNNKPV-KALPTKSDGDTH 787
E + PQ IEPL S+ + +S +V P I W K+ +P+ + K D
Sbjct: 1748 EHDAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFG 1807
Query: 788 SITILKPKKV-KDEGVYTLKAENSEGIAETSAVITV 822
I++ V +D GVY++KA N++G AE A +TV
Sbjct: 1808 YISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTV 1843
Score = 41.5 bits (93), Expect = 0.006
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 526 TVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
TV F +V G P P +TW + +I+ +++ D L+I +V DA + V
Sbjct: 83 TVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRLIIEKVDAHDADMYMLV 142
Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMT 612
A+N G S L V S E T
Sbjct: 143 ARNDGGSFQSRFSLNVLQAKSPEAPEFT 170
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 821 TVEEPTEENA-EPPLFINRFQ-EITVKEKGTIKLVARVT-RNPVP-SITWYRNNEIISPS 876
+VE P E N+ E P F +I V E + AR+ N V ++ WY N + +
Sbjct: 676 SVERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAA 735
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
FD + L + + DSG Y VA N G++ + + EKV +++
Sbjct: 736 HRFHPMFDFGYVALDLLYAYPQ-DSGTYTLVARNELGEARSNVELVVGTEKVLYLE 790
Score = 41.5 bits (93), Expect = 0.006
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 1285 EFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E P + +E + G VTL LV+ P EW++N ++ + + +
Sbjct: 2146 EKPQWVQGFENYENVGEGQTVTLHGLVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN 2205
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
A LTI V D+G+Y R N G A VT
Sbjct: 2206 AILTIVHVLPHDSGVYTCRAWNTQGEASTSATVT 2239
Score = 41.5 bits (93), Expect = 0.006
Identities = 53/264 (20%), Positives = 93/264 (35%), Gaps = 25/264 (9%)
Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
E+++ Q+ Q KL + + +E AP F +L+ +G +FE QV
Sbjct: 3296 ESHFKQHSQAKLQLTANDI------YNESDKRAPEFRTQLQNIGVLEGEFCRFETQVAPI 3349
Query: 537 PRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
P ++ WF+ + F+ D A L + P+D G + CVA N G
Sbjct: 3350 NDPYLKVEWFKDKKPVLLGHRFRSTLDF-GFACLDLLYALPDDTGEYHCVATNRHGQTMI 3408
Query: 595 TTELIVEAPL-----SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP------KAQ 643
+ +L + S + V ++ + P + P +
Sbjct: 3409 SAKLACQGASHVITDSQMPQGLRVSNVKKDNKNIYWSEQGGAVQPKQKQAPQFTIPLRNL 3468
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V E EC + P P + W G + + + + ++ S +I++
Sbjct: 3469 QVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDA--- 3525
Query: 704 QEGTYTVVAVNREGEASLPIVLKI 727
G +A N EGE L I
Sbjct: 3526 --GEVVAIARNTEGETISTATLDI 3547
Score = 40.7 bits (91), Expect = 0.011
Identities = 44/207 (21%), Positives = 76/207 (36%), Gaps = 6/207 (2%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A ++ PP F P++ + ++V P P + W K + V IE
Sbjct: 59 AALVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSGGKYKIE 117
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSM 744
+ L I V Y +VA N G L + + E P+ +S
Sbjct: 118 NGPD-GSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQST 176
Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITI-LKPKKVKDEGV 802
+ G+SV L + G + W K+N+P+ + + + D + T+ + +K+ G
Sbjct: 177 TLYDGDSVKLYCKAAGE-GVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGW 235
Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN 829
Y A N G + V + N
Sbjct: 236 YRCDATNKHGTTTLKGRVVVNSRQKFN 262
Score = 40.7 bits (91), Expect = 0.011
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P + I R++ Q + K T + T + ++WFKDG + SN +LT D L I
Sbjct: 1757 PLDSIDRMEFQSAHFQTKVTPQ---TDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDI 1813
Query: 1166 YDCDLDDAGEYSCEVGNSK 1184
+D+G YS + N+K
Sbjct: 1814 AHTVPEDSGVYSVKASNAK 1832
Score = 40.3 bits (90), Expect = 0.015
Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 730 GEKEPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKS 782
G +EPP + PL++ + V +GE + L QV + + I W ++ + + T
Sbjct: 951 GPQEPPTFVVPLQADLGDVEEGEPIHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFY 1010
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
D S+ IL +D G YT +AENS G AET A I
Sbjct: 1011 DFGFVSLDILG-FYAQDAGTYTCRAENSLGQAETVATI 1047
Score = 40.3 bits (90), Expect = 0.015
Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%)
Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVV--GNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
PP+ + L S+ V +G+ AQ + +P+ ++ W N P+ A + + +
Sbjct: 1882 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 1941
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVIT----------------------VEEPT 826
L + +D G Y++ +NSEG TS ++ +E P
Sbjct: 1942 SLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTRAAILGDTQHEQSWQRIQEIEAPR 2001
Query: 827 EENAEP-------PLFINRFQEITVKEKGTIKLV-ARV--TRNPVPSITWYRNNEIISPS 876
AEP P F+ Q + +G++ L+ AR+ +P + W+ N++ + S
Sbjct: 2002 APGAEPEGPVYEKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMES 2061
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I+ + D + L I V + +G Y C A N +G + A V +
Sbjct: 2062 NWISTSNDFGCVSLRIAPVYAR-HTGVYSCKAWNDSGNAVTSANVGV 2107
Score = 39.5 bits (88), Expect = 0.026
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
Q+P PL+N+ N+ C G P+PKVTW+ +G +
Sbjct: 3457 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQ 3498
Score = 39.5 bits (88), Expect = 0.026
Identities = 21/78 (26%), Positives = 36/78 (46%)
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
++G V + P+P +W K I + K S D K A L + +V AG Y+
Sbjct: 4171 RQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQ 4230
Query: 1360 LRLENNCGHADVEMNVTI 1377
+ + N+ G A + +T+
Sbjct: 4231 IVIRNDKGAATSQAKLTL 4248
Score = 39.1 bits (87), Expect = 0.034
Identities = 58/279 (20%), Positives = 103/279 (36%), Gaps = 22/279 (7%)
Query: 490 EKIDKLPVFEKPT-SEEQSMAPIF-----VEKLRPKHTPDGSTVQFECQVEGY--PRPQI 541
E ++ + E P +E ++ AP++ ++ K +G V FE + PR Q+
Sbjct: 2386 ESWKRIQILEAPKEAEPEAPAPVYDHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQV 2445
Query: 542 TWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV- 600
W R + + + D + TL + +PED G + N G A S+ L
Sbjct: 2446 QWIRNGVPLAHGSKYAIQ-QDFGICTLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCH 2504
Query: 601 --EAPLSD---HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLE 654
+A L D S + AD PP F ++ + E E
Sbjct: 2505 GKDAILGDVQHQESWKRIQEIEAPKQKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFE 2564
Query: 655 CRLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
+ + +P I W GE + + + +D ++ I + G + VA
Sbjct: 2565 ATVEPVDDPTLTINWFLNGEPMSASSRVKMI--NDFGWV--IMDIAQTEPRDSGEWKCVA 2620
Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
N GEA ++++ E ++P +RQ E+
Sbjct: 2621 KNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEA 2659
Score = 38.7 bits (86), Expect = 0.045
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 731 EKEPPQVIEPLKSMI--VRQGESVILSAQVVGNPRPTIT--WCKNNKPVKALPTKSDGDT 786
EKE P + +PL + I V + +++ L AQV T+ W N P+KA +
Sbjct: 1217 EKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKASSRYRVLND 1276
Query: 787 HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE 823
L + +D G YTL NS G AETS V+
Sbjct: 1277 FGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1315
Score = 38.7 bits (86), Expect = 0.045
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PE T+LQN V +G FE ++ D V WFKD + + + T+D L
Sbjct: 3323 PEFRTQLQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACL 3382
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
+ DD GEY C N
Sbjct: 3383 DLLYALPDDTGEYHCVATN 3401
Score = 37.9 bits (84), Expect = 0.078
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
+P + W N I S I+ + L+I ++ + D+G+YKCVA+N G ++
Sbjct: 3110 DPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAA-DAGEYKCVATNVKGSATSV 3168
Query: 919 ARVTID----VEKVTFVKHLQKSYET-EEGKTVILECQTS 953
++ ++ ++ V+ L S E EG ++ LEC+ +
Sbjct: 3169 GKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVT 3208
Score = 37.5 bits (83), Expect = 0.10
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNN 772
E EA P + PP+ L +++G+ L QV V +PR I W N
Sbjct: 2926 EIEAPRPAREDAPDADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNG 2985
Query: 773 KPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+PV K+ D + + L P + +D G +T +A N G E S + V
Sbjct: 2986 QPVNHTNRMKAIHDFGFVVLQLTPAEPQDSGTWTCRATNQHGSDEVSTELKV 3037
Score = 37.1 bits (82), Expect = 0.14
Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 1107 PEIITRLQNQ-KVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
P I+ LQ Q + +G A + + T V W KDG I SN ++ D
Sbjct: 2675 PAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHSNRYKMVHDFGFAV 2734
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIP 1221
L I DAGEY+ V N+ A S +F + IL P N VEI
Sbjct: 2735 LDILHLLKHDAGEYTFRVSNNSGEA-----STSTSFEVSESSGLILQPQNEQKAKAVEIL 2789
Query: 1222 DETL 1225
++ L
Sbjct: 2790 EDNL 2793
Score = 36.7 bits (81), Expect = 0.18
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 36/249 (14%)
Query: 709 TVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPT 765
T+ V++ + P+ L+ + K P+ L+S + +G+S L + V +P
Sbjct: 271 TLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLR 330
Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
I W N K + A + T +D ++ I P V D+G YT+ A N G A SA I V
Sbjct: 331 IAWLLNGKGILASSRIVTFTDFGIAALEI-NPVNVFDQGEYTVVAVNPLGEARVSANIAV 389
Query: 823 --------------------------EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
+ P + + P F + + V E I L ++
Sbjct: 390 IGHGSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKL 449
Query: 857 T--RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
T +P + W + + ++ Q L I S DSG Y C A N G+
Sbjct: 450 TPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSN-DSGLYSCRAFNKLGE 508
Query: 915 SSHGARVTI 923
S + A + I
Sbjct: 509 SENQATIII 517
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P + L++Q+V +G + E +LT D V W DG+E+ ++ + T+ L
Sbjct: 426 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 485
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
I +D+G YSC N
Sbjct: 486 DIPQTSSNDSGLYSCRAFN 504
Score = 36.3 bits (80), Expect = 0.24
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDGD 785
+PP E L ++G+S+ L ++ V +P +TW +N +P+ + +P ++ D
Sbjct: 1485 QPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPLPEASRFMPARNF-D 1543
Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++ IL +D GVYT KA ++ G A TS +
Sbjct: 1544 YVNLDILALYG-EDSGVYTCKAVSAFGEAATSCTV 1577
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P + W+K+G L N + +TT + I S Y+++ASN G + V+
Sbjct: 1781 PNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQ 1840
Query: 1660 LKV 1662
L V
Sbjct: 1841 LTV 1843
Score = 36.3 bits (80), Expect = 0.24
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
+P ++ A P F + + V E + VT P P +TW+ N NF
Sbjct: 3452 QPKQKQA--PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNF 3509
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
DG + + + D+G+ +A N+ G++ A + I
Sbjct: 3510 DG--LHYLTVSKSRISDAGEVVAIARNTEGETISTATLDI 3547
Score = 35.9 bits (79), Expect = 0.32
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870
+ E E+P E+ + P FI I E + +VT P+ I W+++
Sbjct: 1733 VLEAPRAAAPEKPDAEH-DAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDG 1791
Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ + S D I L I + E DSG Y ASN+ G + A++T+
Sbjct: 1792 QPLMNSNRFKLTTDFGYISLDIAHTVPE-DSGVYSVKASNAKGDAEVQAQLTV 1843
Score = 34.7 bits (76), Expect = 0.73
Identities = 17/66 (25%), Positives = 31/66 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P V+W +GN+L ++ +Y T + + I + + S Y+ A N G S + T
Sbjct: 455 PDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSNDSGLYSCRAFNKLGESENQAT 514
Query: 1660 LKVYDK 1665
+ + K
Sbjct: 515 IIIVPK 520
Score = 34.3 bits (75), Expect = 0.97
Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
+P F L+ EV E LE + IN VVW DG + P +KY
Sbjct: 425 LPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFA 483
Query: 1073 KLYIRNTSVHDEGEYSC 1089
L I TS +D G YSC
Sbjct: 484 SLDIPQTSSNDSGLYSC 500
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 1013 KETIPEFIRKLQDFEVKEK-DVAILEVEI---NSETADVVWERDGEIIKPKKNKYDFEKR 1068
++ P+F+ ++Q F +++ + E I N T V W +DG+ + P N+ +
Sbjct: 547 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNANRIQIFQN 605
Query: 1069 GHIRKLYIRNTSVHDEGEYSCIL 1091
+ L + T D G Y+C+L
Sbjct: 606 FGVVSLSLHPTYPEDAGVYTCVL 628
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P +V W K+G + + Y + +V+ I L + + +YT SN +G +S +
Sbjct: 2705 PSIKVEWLKDGQPIFHSNRYKMVHDFGFAVLDILHLLKHDAGEYTFRVSNNSGEASTSTS 2764
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIE 1686
+V S+ G ++ + +++ +E
Sbjct: 2765 FEV----SESSGLILQPQNEQKAKAVE 2787
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASL 1345
PK + ++ G L + Y PN W++N K I D A+L
Sbjct: 298 PKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILASSRIVTFTDFGIAAL 357
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
I V D G Y + N G A V N+ ++
Sbjct: 358 EINPVNVFDQGEYTVVAVNPLGEARVSANIAVI 390
Score = 33.1 bits (72), Expect = 2.2
Identities = 47/216 (21%), Positives = 81/216 (37%), Gaps = 12/216 (5%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P F LR + +G + E ++ P ++ W + PS D A+
Sbjct: 426 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFAS 484
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXA 626
L I + D+G ++C A N G + + +I+ P SD E A
Sbjct: 485 LDIPQTSSNDSGLYSCRAFNKLGESENQATIII-VPKSDLQQFEQHRQLDVEDVREIQFA 543
Query: 627 DILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVA 683
+ + P F + + + + E E R+ I +P ++WL G+ + P+ N
Sbjct: 544 HSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNAN---R 599
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I+ + L + G YT V N G+A
Sbjct: 600 IQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 635
Score = 33.1 bits (72), Expect = 2.2
Identities = 16/47 (34%), Positives = 25/47 (53%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
V W KDG + +N IQ+ + L ++ +DAG Y+C + NS
Sbjct: 585 VSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNS 631
Score = 33.1 bits (72), Expect = 2.2
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 1106 PPEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
PP+ +T+L + V +G + FE I + V+W+ +G+ + S+ L D
Sbjct: 1882 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 1941
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK 1184
L + +DAGEYS V NS+
Sbjct: 1942 SLDLQYTLGEDAGEYSVVVKNSE 1964
Score = 32.7 bits (71), Expect = 3.0
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 7/116 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKN 771
R+ EA P + + E P ++ L+ + +G S L Q V +P + W K+
Sbjct: 2655 RQIEAGKPAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKD 2714
Query: 772 NKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
+P+ D + IL K D G YT + N+ G A TS V E
Sbjct: 2715 GQPIFHSNRYKMVHDFGFAVLDILHLLK-HDAGEYTFRVSNNSGEASTSTSFEVSE 2769
Score = 32.3 bits (70), Expect = 3.9
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 735 PQVIEPLKSMIVRQGES--VILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITI 791
P+ + L + + + E+ V L A V +P I W N +P+ K+ + I +
Sbjct: 823 PKFLNDLPDIQLNEHENIHVDLRATPVNDPTMVIEWFVNGRPLLTGSRVKTLNEFGFIAL 882
Query: 792 -LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+K +D G Y+++A N G A VITV
Sbjct: 883 DIKGAIAEDSGTYSVRASNLLGEAIRQCVITV 914
Score = 32.3 bits (70), Expect = 3.9
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTIT--WCKN 771
+E EA P ++ +PP ++ L I +G++V L AQV ++T W N
Sbjct: 1069 QEIEAPKPAPQEVPDLPHQPPAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVN 1128
Query: 772 NKPV-KA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
+P+ KA D ++ IL +D G YTL N G A+++ I
Sbjct: 1129 GQPLMKAHRFVLSQDFGYIALNILYCYP-EDNGTYTLVVRNRAGEAQSTVDI 1179
Score = 31.9 bits (69), Expect = 5.2
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIA 814
Q + +P ++W K+ +P+ + L P +D GVYT NS G A
Sbjct: 576 QPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 635
Query: 815 ETSAVIT 821
++SA +T
Sbjct: 636 QSSAELT 642
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
+A ++G P P V W G + I+ K +++ + + + +Y I N G
Sbjct: 4179 SAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQIVIRNDKG 4238
Query: 1653 --TSSVEVTL 1660
TS ++TL
Sbjct: 4239 AATSQAKLTL 4248
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/66 (24%), Positives = 29/66 (43%)
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
Q P +W + + + K + D SL I D+G+Y ++ N G A+V
Sbjct: 1778 QTDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEV 1837
Query: 1372 EMNVTI 1377
+ +T+
Sbjct: 1838 QAQLTV 1843
Score = 31.1 bits (67), Expect = 9.0
Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ G P P+V W+ NGN+ + + + + + + + + S + + A NT G +
Sbjct: 3482 VTGYPRPKVTWFINGNQCLHGHRFKLNF-DGLHYLTVSKSRISDAGEVVAIARNTEGETI 3540
Query: 1656 VEVTLKVY 1663
TL ++
Sbjct: 3541 STATLDIF 3548
>AF106579-4|AAK82895.1| 4203|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform b protein.
Length = 4203
Score = 113 bits (271), Expect = 2e-24
Identities = 113/458 (24%), Positives = 188/458 (41%), Gaps = 64/458 (13%)
Query: 500 KPTSEEQSMA--PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
+PT QS P ++L+P G +F + G ++TW + IK +
Sbjct: 3774 QPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTL 3833
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ N ++L I + AG +T +NAAG S L V P +
Sbjct: 3834 ITTTPTN-SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTT------------ 3880
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
+G P FS + + + C++ P+P I W G+ + D
Sbjct: 3881 ------------QGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPND 3928
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---KTGEK-- 732
+ V E + LK +N+ G Y +VA N GEA L + KTG+
Sbjct: 3929 DRFQVVEEGGAYK----LKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAE 3984
Query: 733 -----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
E P+ ++ ++V +G+ SAQ G P PTI W +NN+PVK +
Sbjct: 3985 EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSK 4044
Query: 788 SITILKPKKVKDEGV--YTLKAENSEGIAETSA--VIT------------------VEEP 825
IL+ ++E V Y ++A N G A + A V+T +
Sbjct: 4045 GEAILRISAARNEDVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSS 4104
Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
+ A+ P FI + +I+ ++ T+K A V NP P++ W + IS S + + DG
Sbjct: 4105 DKAAADSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDG 4164
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ L + V + +G+Y+ V N G ++ A++T+
Sbjct: 4165 KRAILELARVTPD-SAGEYQIVIRNDKGAATSQAKLTL 4201
Score = 84.2 bits (199), Expect = 9e-16
Identities = 64/272 (23%), Positives = 121/272 (44%), Gaps = 18/272 (6%)
Query: 722 PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
P KI ++ PP + + LK + G++ + G +TW K+ K +K+
Sbjct: 3773 PQPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRT 3832
Query: 782 SDGDTHSITILKPKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
T + + L ++++ G YT++ EN+ G E+ A +TV PT + P F R
Sbjct: 3833 LITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPD-FSARL 3891
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ +++ G + ++ P P+I W+++ + + + +G +L +N+ S
Sbjct: 3892 NDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIIS-T 3950
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE------------TEEGKTVI 947
D+G Y+ VA N G++ AR+ ++++K YE +EGK
Sbjct: 3951 DAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQ 4010
Query: 948 LECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977
Q S + +WY N + + D EI Q
Sbjct: 4011 FSAQFSGFPDPTIRWYRNNEPVKHADGYEISQ 4042
Score = 72.5 bits (170), Expect = 3e-12
Identities = 83/350 (23%), Positives = 137/350 (39%), Gaps = 24/350 (6%)
Query: 491 KIDKLPVFEKPTSEEQSMA-----PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITW 543
K+DK+ P ++ Q ++ P F L+ + +G + + E + P +I W
Sbjct: 215 KVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAW 274
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
I S + + D +A L I V D G +T VA N G A + + V
Sbjct: 275 LLNGKGILASSRI-VTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGEARVSANIAVIGH 333
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIP---PTFSKKPKAQYVDEGSDILLECRLVAI 660
S + + A G P F ++Q V EG I LE +L I
Sbjct: 334 GSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKLTPI 393
Query: 661 PEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+PD + WL G E+ ++ + H + S L I G Y+ A N+ GE
Sbjct: 394 NDPDLRVVWLLDGNELPSNDKYRQTLS---HGFAS-LDIPQTSSNDSGLYSCRAFNKLGE 449
Query: 719 A--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ--GESVI-LSAQVVGNPRPTITWCKNNK 773
+ I++ + + P+ + ++ Q G S Q + +P ++W K+ +
Sbjct: 450 SENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQ 509
Query: 774 PVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIAETSAVIT 821
P+ + L P +D GVYT NS G A++SA +T
Sbjct: 510 PLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQAQSSAELT 559
Score = 66.1 bits (154), Expect = 3e-10
Identities = 119/539 (22%), Positives = 206/539 (38%), Gaps = 81/539 (15%)
Query: 474 LMDENNYTQYLQKKLN-EKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFEC 531
L+ + ++ LQK E IDK + P E + P +V+ ++ +G TV
Sbjct: 2030 LLLDTSHPASLQKIQELEAIDKYARLDAPEREYEK--PQWVQGFENYENVGEGQTVTLHG 2087
Query: 532 QVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
VE G P ++ W ++ + F+ Y+ N A L I V P D+G +TC A N
Sbjct: 2088 LVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN-AILTIVHVLPHDSGVYTCRAWNTQ 2146
Query: 590 GFASSTTELIV---EAPLSDHGSEMT---VXXXXXXXXXXXXADILEGIPPTF-SKKPKA 642
G AS++ + E L D ++ + +I++ P F ++ A
Sbjct: 2147 GEASTSATVTTAGYEKILYDSQHPVSWERIQELEAPKIVEEIEEIVQKEKPNFLTQLESA 2206
Query: 643 QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDE-----------NISVAIESDMH 689
+ V EG + LE +P+ + W G+ + + + ++ ++ H
Sbjct: 2207 ENVPEGVPLHLESTFQPARDPELKVVWQKNGQPLGASQLVQTKHELGWATLDISSANEDH 2266
Query: 690 MYCSVLKITNVKKFQ--------EGTYTVVAVNREGEASLPIVLKIKTGEKEP------- 734
L ITN + GT ++ R E+ I + E EP
Sbjct: 2267 NGVYTLTITNSEGEAVSTASIRVAGTGPILGNTRHEESWKRIQILEAPKEAEPEAPAPVY 2326
Query: 735 --PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
P + + +G+ V A + V +PR + W +N P+ + I
Sbjct: 2327 DHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQVQWIRNGVPLAHGSKYAIQQDFGIC 2386
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVI----------------------TVEEPT 826
L +DEGVY L+ N EG A +SA + +E P
Sbjct: 2387 TLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCHGKDAILGDVQHQESWKRIQEIEAPK 2446
Query: 827 EENAE-------PPLFINRFQ---EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
++ E PP FI + + + + +P +I W+ N E +S S
Sbjct: 2447 QKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSAS 2506
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
+ D + + I + DSG++KCVA N+AG++ A + + ++V LQ
Sbjct: 2507 SRVKMINDFGWVIMDIAQTEPR-DSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQ 2564
Score = 64.1 bits (149), Expect = 1e-09
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 23/248 (9%)
Query: 500 KPTSEEQS-MAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQ 554
KP+ ++ + P+F ++L P +G +V +C V+ P +I WF +
Sbjct: 1260 KPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGS 1319
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDH- 607
+ +D V L + PED GT+TC A N G +TT++ +E L H
Sbjct: 1320 RIRTIHDFGYVG-LEFLHIHPEDTGTYTCKATNLIG--EATTDIFLECKPRRNIYLDTHH 1376
Query: 608 -GSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD- 664
S + L PPTF++ + EG I LECRL+ + +P
Sbjct: 1377 ESSWQKIQEIENRVDEREPTPELTFQPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTM 1436
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+ W G+ + A D Y + L I + G YT AV+ GEA+
Sbjct: 1437 RVTWTRNGQPLPEASRFMPARNFD---YVN-LDILALYGEDSGVYTCKAVSAFGEAATSC 1492
Query: 724 VLKIKTGE 731
+K G+
Sbjct: 1493 TVKCAAGK 1500
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/319 (22%), Positives = 119/319 (37%), Gaps = 27/319 (8%)
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
+ PP I +L+ + G A F IE + V W KDG EI+ + +T
Sbjct: 3783 QAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSS 3842
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCT----AILTVEEPSI-----NFTLRLPEFILVPANTD 1213
L I + AGEY+ + N+ T A LTV P+ +F+ RL + + + N
Sbjct: 3843 LHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLND-LRIQQNGP 3901
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271
A + +I E + W+K + + ++F ++ + L D Y V
Sbjct: 3902 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 3961
Query: 1272 ---DAKSTTKLKVEVV-------EFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+A+ +L V + E P P+ + + G + FP P
Sbjct: 3962 GVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDP 4021
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W N++ +K + S A L I N D YK+ N G A N+ +
Sbjct: 4022 TIRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVL 4081
Query: 1378 LDKPSPPGKPNILEIDSSS 1396
+ K I S+S
Sbjct: 4082 TPRSGRIAKSTISRGGSAS 4100
Score = 62.1 bits (144), Expect = 4e-09
Identities = 83/338 (24%), Positives = 135/338 (39%), Gaps = 32/338 (9%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
P F L P +G ECQV PR I WF + + + +D V
Sbjct: 2862 PKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIHDFGFVV 2921
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---------PLSDHGSEMT-VXXX 616
L + P+D+GT+TC A N G +TEL V ++ +T +
Sbjct: 2922 -LQLTPAEPQDSGTWTCRATNQHGSDEVSTELKVVGGGGVSYEWQSTAERKERITELEDW 2980
Query: 617 XXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
++ P+FS+ ++E C L I +P + W G
Sbjct: 2981 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHP 3040
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK- 732
I IS E + + L I ++ G Y VA N +G A+ + +++ +
Sbjct: 3041 IPYSNRISCTNEFGV----ATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQI 3096
Query: 733 EPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDG 784
+ PQV++ L + + +G+S+ L +V + +PR + W +N P+ + PT G
Sbjct: 3097 DAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFG 3156
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S+ IL +D G Y L N +G A + ITV
Sbjct: 3157 FV-SLDILYAYP-EDNGDYELVVRNDKGEARSKTKITV 3192
Score = 59.3 bits (137), Expect = 3e-08
Identities = 43/197 (21%), Positives = 80/197 (40%), Gaps = 20/197 (10%)
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRX 1533
T+ ++P L ++ + N E +C GG P+P + W++DG+ L + E
Sbjct: 3880 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 3939
Query: 1534 XXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVGIQ--------------QKPVITISNE 1578
Y+ +A N GE + + + P T +
Sbjct: 3940 YKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQ 3999
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
I G ++ +A G P P + WY+N +++ Y I+ + +++RI +
Sbjct: 4000 PIVVDEGKGAQF--SAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4057
Query: 1639 HSSKYTIEASNTAGTSS 1655
++Y +EASN AG +S
Sbjct: 4058 DVAEYKVEASNPAGKAS 4074
Score = 54.8 bits (126), Expect = 6e-07
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+Q AP F LR + +FEC V GYPRP++TWF F++ +D +
Sbjct: 3371 KQKQAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLH 3430
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
T+ + DAG +A+N G ST L
Sbjct: 3431 YLTVSKSRI--SDAGEVVAIARNTEGETISTATL 3462
Score = 53.6 bits (123), Expect = 1e-06
Identities = 49/212 (23%), Positives = 82/212 (38%), Gaps = 15/212 (7%)
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKATY 1529
I ++K PT+ + LK + E + + F G KVTW +DGK++K T T
Sbjct: 3778 IGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTT 3837
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQK 1583
Y N G VE+ + + + P + D++ +
Sbjct: 3838 PTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQ 3897
Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
E+ + I G P P + W+K+G L ND + + + ++ + + + Y
Sbjct: 3898 QNGPAEF--SCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIY 3955
Query: 1644 TIEASNTAGTSSVEVTLKV-YDKPSK--PEGP 1672
I A N G + + L V K K EGP
Sbjct: 3956 EIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 3987
Score = 53.2 bits (122), Expect = 2e-06
Identities = 56/223 (25%), Positives = 85/223 (38%), Gaps = 17/223 (7%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P F+++L P + FE VE P +T WF + S +M +D
Sbjct: 2460 PRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMI-NDFGWV 2518
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTT-------ELIVEAPLSDHGSEMTVXXXXXX 619
+ I + P D+G + CVAKNAAG A ST E+I++ L +
Sbjct: 2519 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEAGK 2578
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVPD 677
D P + ++EG L+ + + +P I WL G+ I
Sbjct: 2579 PAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHS 2638
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
+ + +VL I ++ K G YT N GEAS
Sbjct: 2639 NRYKMVHDFGF----AVLDILHLLKHDAGEYTFRVSNNSGEAS 2677
Score = 52.0 bits (119), Expect = 5e-06
Identities = 64/265 (24%), Positives = 102/265 (38%), Gaps = 22/265 (8%)
Query: 470 PAQYLMDENNYTQYLQK-KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGST 526
PA ++ + + + L K E ++K E Q P FV L+ +G
Sbjct: 833 PAGQILSDTQHQESLGKINYLENLNKYGRVEIEDKGPQE-PPTFVVPLQADLGDVEEGEP 891
Query: 527 VQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
+ ECQV +I W R + F+ +YD V+ L I + +DAGT+TC
Sbjct: 892 IHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFYDFGFVS-LDILGFYAQDAGTYTCR 950
Query: 585 AKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
A+N+ G A + + + + S + L PP F K
Sbjct: 951 AENSLGQAETVATIRCAPKDAILGAVQHPRSYARIQEIEAPKPAPQEVPDLPHQPPAFVK 1010
Query: 639 K--PKAQYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSV 694
+ P Q + EG ++ LE ++ + + WL G+ ++ + D
Sbjct: 1011 QLGPAIQCM-EGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRF--VLSQDFGYI--A 1065
Query: 695 LKITNVKKFQEGTYTVVAVNREGEA 719
L I GTYT+V NR GEA
Sbjct: 1066 LNILYCYPEDNGTYTLVVRNRAGEA 1090
Score = 51.6 bits (118), Expect = 6e-06
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 1191 VEEPSINFTLRLPEF-ILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISD 1247
V+ P+ +F+ L + L A+ A++ V P D TL V W I + + + ++
Sbjct: 2993 VDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNE 3052
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP-----PKIVDY--EREYRI 1299
TL+I+ D EY CV + K S T + VE P++V + I
Sbjct: 3053 FGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENI 3112
Query: 1300 KRGSDVTLLVDYQAFPQP--NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
G + L P + EW+ N + + KP+ + SL I D G
Sbjct: 3113 LEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFVSLDILYAYPEDNGD 3172
Query: 1358 YKLRLENNCGHADVEMNVTILDKPS 1382
Y+L + N+ G A + +T+L +PS
Sbjct: 3173 YELVVRNDKGEARSKTKITVLPRPS 3197
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/184 (27%), Positives = 82/184 (44%), Gaps = 17/184 (9%)
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
+P F L+ EV E LE + IN VVW DG + P +KY
Sbjct: 366 LPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFA 424
Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAE--VTVV-------ELPPEIITRLQNQKVNKG-N 1122
L I TS +D G YSC ++ +E T++ +L P+ ++++Q +
Sbjct: 425 SLDIPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELG 484
Query: 1123 KATFEIELTK-GDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
++ FE + D +R W KDG + +N IQ+ + L ++ +DAG Y+C
Sbjct: 485 RSFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCV 544
Query: 1180 VGNS 1183
+ NS
Sbjct: 545 LFNS 548
Score = 50.8 bits (116), Expect = 1e-05
Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 23/273 (8%)
Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR-PKHTPDGSTVQFECQ 532
L +N + L + + + P E+ E + P+F+E L P T +G F +
Sbjct: 2692 LQPQNEQKAKAVEILEDNLRRRP--EEIEQELKEATPVFIEPLSAPVETEEGGRAHFTAR 2749
Query: 533 VEGYP--RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
E + Q+ W+ +K + + L I +PED G + C A N G
Sbjct: 2750 YEPVNDNQLQVQWYHDGRPLKNGSRIKTI-NSFGYVVLEISPTYPEDNGEYICRAVNRVG 2808
Query: 591 FASSTTEL-------IVEA---PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKK 639
A ++T+L I+ A P + + A + PP F S
Sbjct: 2809 EAVTSTKLTCTPKEGIISATQLPERMANAGRRIAEIEAPRPAREDAPDADHGPPKFTSAL 2868
Query: 640 PKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
+ EG LEC++ + +P I W G+ + N + +++ VL++
Sbjct: 2869 AGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPV----NHTNRMKAIHDFGFVVLQL 2924
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730
T + GT+T A N+ G + LK+ G
Sbjct: 2925 TPAEPQDSGTWTCRATNQHGSDEVSTELKVVGG 2957
Score = 50.4 bits (115), Expect = 1e-05
Identities = 63/272 (23%), Positives = 109/272 (40%), Gaps = 31/272 (11%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDG 885
NA PP F+ Q + K T+ A+V P PS+TW +++ + S I DG
Sbjct: 64 NARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDG 123
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
L+I VD+ D+ Y VA N G + ++D + H+ + +EG
Sbjct: 124 SG-RLIIEKVDAH-DADMYMLVARNDGG----SFQSSVDNKGNETTLHINNA-TMKEGGW 176
Query: 946 VILECQTSHTVST----KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
+ H +T +++++ +G HRE+I + +
Sbjct: 177 YRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREMITLRKVDKVERSRTPVNQL------- 229
Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKP 1058
Q+ S ++ P+F LQ ++ E A LE++ + + W +G+ I
Sbjct: 230 --QDVS----ASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILA 283
Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
F G I L I +V D+GEY+ +
Sbjct: 284 SSRIVTFTDFG-IAALEINPVNVFDQGEYTVV 314
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816
+G+P + W N P+ S + + L K + D G Y A N +G A +
Sbjct: 3025 IGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATS 3084
Query: 817 SAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVT--RNPVPSITWYRNNEII 873
I VE T+ +A P + + + E +I L RVT +P + W RN +
Sbjct: 3085 VGKIAVESSTQIDA-PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPL 3143
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ F+ + L I E D+GDY+ V N G++ ++T+
Sbjct: 3144 PEASRFKPTFEFGFVSLDILYAYPE-DNGDYELVVRNDKGEARSKTKITV 3192
Score = 49.6 bits (113), Expect = 2e-05
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 16/176 (9%)
Query: 556 FQMYYDDD-NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS---EM 611
FQ D+ N TL I ++ G + C A N G + ++V + +G EM
Sbjct: 151 FQSSVDNKGNETTLHINNATMKEGGWYRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREM 210
Query: 612 -TVXXXXXXXXXXXXADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPD- 664
T+ + L+ + P F ++Q + EG LE + + +P+
Sbjct: 211 ITLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNL 270
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
IAWL G+ I+ I + + + L+I V F +G YTVVAVN GEA
Sbjct: 271 RIAWLLNGKGILASSRIVTFTDFGI----AALEINPVNVFDQGEYTVVAVNPLGEA 322
Score = 48.4 bits (110), Expect = 6e-05
Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 20/243 (8%)
Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
E+P AP F +L K + V FE ++ + + W+ + +
Sbjct: 595 ERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAAHR 654
Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP----LSDHGSE- 610
F +D VA L + +P+D+GT+T VA+N G A S EL+V L H E
Sbjct: 655 FHPMFDFGYVA-LDLLYAYPQDSGTYTLVARNELGEARSNVELVVGTEKVLYLEPHHPEG 713
Query: 611 MTVXXXXXXXXXXXXADI----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD-- 664
+ A++ + P + P Q ++E +I ++ R + +P
Sbjct: 714 LERIKELEQDRRQGIAEVEDRTCDAAPKFLNDLPDIQ-LNEHENIHVDLRATPVNDPTMV 772
Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
I W G ++ + E L I GTY+V A N GEA V
Sbjct: 773 IEWFVNGRPLLTGSRVKTLNEFGF----IALDIKGAIAEDSGTYSVRASNLLGEAIRQCV 828
Query: 725 LKI 727
+ +
Sbjct: 829 ITV 831
Score = 48.4 bits (110), Expect = 6e-05
Identities = 52/257 (20%), Positives = 98/257 (38%), Gaps = 10/257 (3%)
Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
E+D VK T T ++L+ + + +I E + ++ + +Q
Sbjct: 3634 ELDVPARDQVKLKTAKPTRGKDLEAGEKVKLKTEKAKIKEIQQKPEQPKEEPIVHKDAVQ 3693
Query: 1481 SPTVEKPLKNI-----TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535
T + P I T + +D++ T V +P + R K+ + T ++
Sbjct: 3694 LKTQQLPKTGIKGDHFTVDREKDLKET---PAVVKPVIEETRISNKVYLSVETADSFSQV 3750
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
+ I F+ T +G ++ TIS + + ++G
Sbjct: 3751 QRLEYSPRSPRRERIIGFHMIRPQPTK--IGQSKQAPPTISQQLKPLQGELGKAAKFVIE 3808
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
G P +V W K+G ++++ ITT S + I L+ SH+ +YT+ N AGT
Sbjct: 3809 FAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVE 3868
Query: 1656 VEVTLKVYDKPSKPEGP 1672
L V ++ + P
Sbjct: 3869 SLANLTVAPPTTQGKAP 3885
Score = 48.4 bits (110), Expect = 6e-05
Identities = 52/257 (20%), Positives = 97/257 (37%), Gaps = 24/257 (9%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PP I + + + G ++++ W+ + K IK T + ++SL
Sbjct: 3785 PPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLH 3844
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
I ++EN+ AG Y +RLEN G + N+T+ P+ GK + + I + P
Sbjct: 3845 IGRLENSHAGEYTVRLENAAGTVESLANLTVA-PPTTQGKAPDFSARLNDLRIQQNGPAE 3903
Query: 1407 TG------NSTIIYYVVEYQEIDTTEWISV-----------KNITKTQTSIQNL-KTNSS 1448
I + + Q + + V NI T I + N
Sbjct: 3904 FSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGV 3963
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
R A V++ + E + + ++P ++ I + + + + F G
Sbjct: 3964 GEARCKARLNVNLQKTGKGAE-----EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGF 4018
Query: 1509 PQPKVTWYRDGKKLKTA 1525
P P + WYR+ + +K A
Sbjct: 4019 PDPTIRWYRNNEPVKHA 4035
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDG-STV 527
+P D Y+ KL E ++ + S Q + P F+ +++P H
Sbjct: 428 IPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSS-QDLTPKFLSQIQPFHCEQELGRS 486
Query: 528 QFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
FE +++ P +++W + + + Q++ + V +L + +PEDAG +TCV
Sbjct: 487 FFEARIQPINDPTLRVSWLKDGQPLPNANRIQIF-QNFGVVSLSLHPTYPEDAGVYTCVL 545
Query: 586 KNAAGFASSTTEL 598
N+ G A S+ EL
Sbjct: 546 FNSHGQAQSSAEL 558
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 13/197 (6%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
P L+S V +G+ + L ++ + +P + W + + + +H L
Sbjct: 367 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 426
Query: 793 KPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK-GT 849
+ D G+Y+ +A N G +E A I + + ++ P F+++ Q +++ G
Sbjct: 427 DIPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPK-FLSQIQPFHCEQELGR 485
Query: 850 IKLVARVT--RNPVPSITWYRNNEIISPSETIT--QNFDGENIELVITNVDSEIDSGDYK 905
AR+ +P ++W ++ + + + I QNF ++ L T + D+G Y
Sbjct: 486 SFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPE---DAGVYT 542
Query: 906 CVASNSAGKSSHGARVT 922
CV NS G++ A +T
Sbjct: 543 CVLFNSHGQAQSSAELT 559
Score = 46.0 bits (104), Expect = 3e-04
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 11/157 (7%)
Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQVV--GNPRPTITWCKNNKPVKA---LPTKSDGDT 786
E P ++PL+S+ + +G +L A++V +P + W N++P+ + T +D
Sbjct: 1930 EKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMESNWISTSNDFGC 1989
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITV 844
S+ I P + GVY+ KA N G A TSA + V+ E + P + + QE+
Sbjct: 1990 VSLRIA-PVYARHTGVYSCKAWNDSGNAVTSANVGVQGSEGLLLDTSHPASLQKIQELEA 2048
Query: 845 KEKGTIKLVARVTRNPVPS-ITWYRNNEIISPSETIT 880
+K +L A P + + N E + +T+T
Sbjct: 2049 IDK-YARLDAPEREYEKPQWVQGFENYENVGEGQTVT 2084
Score = 46.0 bits (104), Expect = 3e-04
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L+++NVKK + Y + +G A P +K+ PQ PL+++ V + +
Sbjct: 3347 LRVSNVKKDNKNIYW----SEQGGAVQP-------KQKQAPQFTIPLRNLQVTENQPARF 3395
Query: 755 SAQVVGNPRPTITWCKN-NKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENSEG 812
V G PRP +TW N N+ + K + D H +T+ K ++ D G A N+EG
Sbjct: 3396 ECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSK-SRISDAGEVVAIARNTEG 3454
Query: 813 IAETSAVITV 822
++A + +
Sbjct: 3455 ETISTATLDI 3464
Score = 45.6 bits (103), Expect = 4e-04
Identities = 42/192 (21%), Positives = 82/192 (42%), Gaps = 15/192 (7%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P + L++Q+V +G + E +LT D V W DG+E+ ++ + T+ L
Sbjct: 367 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 426
Query: 1164 KIYDCDLDDAGEYSC----EVGNSKCTAILTV-----EEPSINFTLRLPEFILVPANTDA 1214
I +D+G YSC ++G S+ A + + ++ + F ++ F +
Sbjct: 427 DIPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRS 486
Query: 1215 YLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
+ I D TL V+W K + + + + + +L + +D YTCVL
Sbjct: 487 FFEARIQPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLF 546
Query: 1272 DAKSTTKLKVEV 1283
++ + E+
Sbjct: 547 NSHGQAQSSAEL 558
Score = 45.6 bits (103), Expect = 4e-04
Identities = 55/231 (23%), Positives = 89/231 (38%), Gaps = 18/231 (7%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDF 556
EKP +E AP F+E L + + F+ +V + P +I WF+ + S F
Sbjct: 1660 EKPDAEHD--APQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRF 1717
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMT- 612
++ D ++ L I PED+G ++ A NA G A +L V L D E +
Sbjct: 1718 KLTTDFGYIS-LDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTVTGNAVILGDTQHEQSW 1776
Query: 613 ---VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAW 667
D+ G P ++ V EG E + + +P + W
Sbjct: 1777 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 1836
Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
G + + + +D + L+ T + G Y+VV N EGE
Sbjct: 1837 YLNGNPL--SASSRRILRNDFGLVSLDLQYTLGE--DAGEYSVVVKNSEGE 1883
Score = 44.8 bits (101), Expect = 7e-04
Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 17/197 (8%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE- 601
W +K S +++ +D +L I + ED+G +T V N+AG A ++ E V+
Sbjct: 1175 WLFNGNPLKASSRYRVL-NDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVDR 1233
Query: 602 --APLSD--HGSEM-TVXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLE 654
+ LSD H + + D PP F+++ + + EG + ++
Sbjct: 1234 LKSILSDTAHPESLRRIREMEQLQPAKPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMD 1293
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVV 711
C + I +P I W G ++ I +H + V L+ ++ GTYT
Sbjct: 1294 CVVQPINDPSLRIEWFHDGRPLMFGSRIRT-----IHDFGYVGLEFLHIHPEDTGTYTCK 1348
Query: 712 AVNREGEASLPIVLKIK 728
A N GEA+ I L+ K
Sbjct: 1349 ATNLIGEATTDIFLECK 1365
Score = 44.8 bits (101), Expect = 7e-04
Identities = 63/285 (22%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
K+ P ++L+ + + A +E + V W +DG+ IK +
Sbjct: 3782 KQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTN- 3840
Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE-----LPPEIITRLQNQKVNKGN 1122
L+I GEY+ L + + T E +TV P+ RL + ++ +
Sbjct: 3841 SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNG 3900
Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
A F ++ + ++WFKDG + + Q+ +G KLK + DAG Y
Sbjct: 3901 PAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAK 3960
Query: 1179 -EVGNSKCTAILTV----------EEP---SINFTLRLPEFILVPANTDAYLTVE---IP 1221
VG ++C A L V E P + FT ++ + I+V A + + P
Sbjct: 3961 NGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQI-QPIVVDEGKGAQFSAQFSGFP 4019
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
D T + WY+ ++ + + + + L I +D EY
Sbjct: 4020 DPT--IRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEY 4062
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 25/223 (11%)
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD----VAILEVEINSETADVVWERDGE 1054
I + +E + V P F + L D ++ E D V +LE I T V WE +G
Sbjct: 2981 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLE-PIGDPTLRVQWEHNGH 3039
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELP----- 1106
I P N+ + L I++ D GEY C+ ++ + + VE
Sbjct: 3040 PI-PYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDA 3098
Query: 1107 PEIITRLQNQKVN--KGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
P+++ +L + N +G+ E +T D V W ++G+ + ++ + T +
Sbjct: 3099 PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFV 3158
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK-----CTAILTVEEPSINFT 1199
L I +D G+Y V N K T I + PS+++T
Sbjct: 3159 SLDILYAYPEDNGDYELVVRNDKGEARSKTKITVLPRPSLDYT 3201
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P I +L + +G+ F E+ + V+W G I SN+++++ DGK+ L++
Sbjct: 4112 PHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILEL 4171
Query: 1166 YDCDLDDAGEYSCEVGNSKCTA 1187
D AGEY + N K A
Sbjct: 4172 ARVTPDSAGEYQIVIRNDKGAA 4193
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGSTVQFECQVEGYPRPQIT--WFR 545
++I+ E +E + AP FV +L +G + E QVE Q+T WF
Sbjct: 1516 QEIENREKLEAVDAEPEKTAPKFVTQLNSSLGELQEGVPIHLEAQVEPTNDNQLTVQWFH 1575
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ F+ +D VA L I F +D G + CVA+N+ G A + V
Sbjct: 1576 NGQPLANGHRFRTRHDFGYVA-LDILYAFAQDTGEWACVARNSLGEAQTIANFTV 1629
Score = 43.6 bits (98), Expect = 0.002
Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 24/247 (9%)
Query: 490 EKIDKLPVFEKPTSEEQSMA---PIFVEKLRPKH-TPDGSTVQFECQVEGY--PRPQITW 543
+KI + P EE + P FV +L +G FE Q + P+ + W
Sbjct: 1777 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 1836
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-- 601
+ + S ++ +D + +L ++ EDAG ++ V KN+ G ++ +L
Sbjct: 1837 YLNGNPLSASSR-RILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTR 1895
Query: 602 -APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD------EGSDILLE 654
A L D E + EG P + K Q + EGS LLE
Sbjct: 1896 AAILGDTQHEQSWQRIQEIEAPRAPGAEPEG--PVYEKPSFVQPLQSVGDLPEGSVALLE 1953
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
RLV + +P+ + W + + ++ IS + + C L+I V G Y+ A
Sbjct: 1954 ARLVPVNDPNLRVQWFYNDQPLMESNWISTSND----FGCVSLRIAPVYARHTGVYSCKA 2009
Query: 713 VNREGEA 719
N G A
Sbjct: 2010 WNDSGNA 2016
Score = 43.2 bits (97), Expect = 0.002
Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 18/223 (8%)
Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P FV++L P +G V E QV +T W + + F + D +A
Sbjct: 1006 PAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRFVLSQDFGYIA 1065
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMTVXXXXXXXXXX 623
L I +PED GT+T V +N AG A ST ++ +D ++
Sbjct: 1066 -LNILYCYPEDNGTYTLVVRNRAGEAQSTVDINCGHTGGNFTDSFHPNSLHRIAELETPI 1124
Query: 624 XXADIL---EGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVP 676
A+ L E PT +K A V E + LE ++ I + + WLF G +
Sbjct: 1125 QRAEPLPDKEKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKA 1184
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
V +D L I + G YT+V N G A
Sbjct: 1185 SSRYRVL--NDFGFVS--LDIDYIIAEDSGKYTLVVYNSAGRA 1223
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT--ITWCKNNKPV-KALPTKSDGDTH 787
E + PQ IEPL S+ + +S +V P I W K+ +P+ + K D
Sbjct: 1665 EHDAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFG 1724
Query: 788 SITILKPKKV-KDEGVYTLKAENSEGIAETSAVITV 822
I++ V +D GVY++KA N++G AE A +TV
Sbjct: 1725 YISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTV 1760
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 821 TVEEPTEENA-EPPLFINRFQ-EITVKEKGTIKLVARVT-RNPVP-SITWYRNNEIISPS 876
+VE P E N+ E P F +I V E + AR+ N V ++ WY N + +
Sbjct: 593 SVERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAA 652
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
FD + L + + DSG Y VA N G++ + + EKV +++
Sbjct: 653 HRFHPMFDFGYVALDLLYAYPQ-DSGTYTLVARNELGEARSNVELVVGTEKVLYLE 707
Score = 41.5 bits (93), Expect = 0.006
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 1285 EFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E P + +E + G VTL LV+ P EW++N ++ + + +
Sbjct: 2063 EKPQWVQGFENYENVGEGQTVTLHGLVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN 2122
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
A LTI V D+G+Y R N G A VT
Sbjct: 2123 AILTIVHVLPHDSGVYTCRAWNTQGEASTSATVT 2156
Score = 41.5 bits (93), Expect = 0.006
Identities = 53/264 (20%), Positives = 93/264 (35%), Gaps = 25/264 (9%)
Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
E+++ Q+ Q KL + + +E AP F +L+ +G +FE QV
Sbjct: 3213 ESHFKQHSQAKLQLTANDI------YNESDKRAPEFRTQLQNIGVLEGEFCRFETQVAPI 3266
Query: 537 PRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
P ++ WF+ + F+ D A L + P+D G + CVA N G
Sbjct: 3267 NDPYLKVEWFKDKKPVLLGHRFRSTLDF-GFACLDLLYALPDDTGEYHCVATNRHGQTMI 3325
Query: 595 TTELIVEAPL-----SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP------KAQ 643
+ +L + S + V ++ + P + P +
Sbjct: 3326 SAKLACQGASHVITDSQMPQGLRVSNVKKDNKNIYWSEQGGAVQPKQKQAPQFTIPLRNL 3385
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V E EC + P P + W G + + + + ++ S +I++
Sbjct: 3386 QVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDA--- 3442
Query: 704 QEGTYTVVAVNREGEASLPIVLKI 727
G +A N EGE L I
Sbjct: 3443 --GEVVAIARNTEGETISTATLDI 3464
Score = 41.1 bits (92), Expect = 0.008
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSI 789
PPQ + +S+ + E+V SA+VVG P P++TW K++ V ++ D
Sbjct: 67 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGR 126
Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETS 817
I++ D +Y L A N G ++S
Sbjct: 127 LIIEKVDAHDADMYMLVARNDGGSFQSS 154
Score = 40.7 bits (91), Expect = 0.011
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P + I R++ Q + K T + T + ++WFKDG + SN +LT D L I
Sbjct: 1674 PLDSIDRMEFQSAHFQTKVTPQ---TDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDI 1730
Query: 1166 YDCDLDDAGEYSCEVGNSK 1184
+D+G YS + N+K
Sbjct: 1731 AHTVPEDSGVYSVKASNAK 1749
Score = 40.3 bits (90), Expect = 0.015
Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 730 GEKEPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKS 782
G +EPP + PL++ + V +GE + L QV + + I W ++ + + T
Sbjct: 868 GPQEPPTFVVPLQADLGDVEEGEPIHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFY 927
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
D S+ IL +D G YT +AENS G AET A I
Sbjct: 928 DFGFVSLDILG-FYAQDAGTYTCRAENSLGQAETVATI 964
Score = 40.3 bits (90), Expect = 0.015
Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%)
Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVV--GNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
PP+ + L S+ V +G+ AQ + +P+ ++ W N P+ A + + +
Sbjct: 1799 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 1858
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVIT----------------------VEEPT 826
L + +D G Y++ +NSEG TS ++ +E P
Sbjct: 1859 SLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTRAAILGDTQHEQSWQRIQEIEAPR 1918
Query: 827 EENAEP-------PLFINRFQEITVKEKGTIKLV-ARV--TRNPVPSITWYRNNEIISPS 876
AEP P F+ Q + +G++ L+ AR+ +P + W+ N++ + S
Sbjct: 1919 APGAEPEGPVYEKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMES 1978
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I+ + D + L I V + +G Y C A N +G + A V +
Sbjct: 1979 NWISTSNDFGCVSLRIAPVYAR-HTGVYSCKAWNDSGNAVTSANVGV 2024
Score = 39.9 bits (89), Expect = 0.019
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 526 TVQFECQVEGYPRPQITWFRQT-AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
TV F +V G P P +TW + +I+ +++ D L+I +V DA + V
Sbjct: 84 TVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRLIIEKVDAHDADMYMLV 143
Query: 585 AKNAAGFASSTTE 597
A+N G S+ +
Sbjct: 144 ARNDGGSFQSSVD 156
Score = 39.5 bits (88), Expect = 0.026
Identities = 74/336 (22%), Positives = 128/336 (38%), Gaps = 45/336 (13%)
Query: 709 TVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPT 765
T+ V++ + P+ L+ + K P+ L+S + +G+S L + V +P
Sbjct: 212 TLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLR 271
Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
I W N K + A + T +D ++ I P V D+G YT+ A N G A SA I V
Sbjct: 272 IAWLLNGKGILASSRIVTFTDFGIAALEI-NPVNVFDQGEYTVVAVNPLGEARVSANIAV 330
Query: 823 --------------------------EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
+ P + + P F + + V E I L ++
Sbjct: 331 IGHGSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKL 390
Query: 857 T--RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
T +P + W + + ++ Q L I S DSG Y C A N G+
Sbjct: 391 TPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSN-DSGLYSCRAFNKLGE 449
Query: 915 SSHGARVTI---DVEKVT--FVKHLQKSY-ETEEGKTVI---LECQTSHTVSTKWYHNKK 965
S + A + I + +T F+ +Q + E E G++ ++ T+ W + +
Sbjct: 450 SENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQ 509
Query: 966 EISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
+ + +I Q D GV C++
Sbjct: 510 PLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVL 545
Score = 39.5 bits (88), Expect = 0.026
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
Q+P PL+N+ N+ C G P+PKVTW+ +G +
Sbjct: 3374 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQ 3415
Score = 39.5 bits (88), Expect = 0.026
Identities = 21/78 (26%), Positives = 36/78 (46%)
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
++G V + P+P +W K I + K S D K A L + +V AG Y+
Sbjct: 4124 RQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQ 4183
Query: 1360 LRLENNCGHADVEMNVTI 1377
+ + N+ G A + +T+
Sbjct: 4184 IVIRNDKGAATSQAKLTL 4201
Score = 39.1 bits (87), Expect = 0.034
Identities = 58/279 (20%), Positives = 103/279 (36%), Gaps = 22/279 (7%)
Query: 490 EKIDKLPVFEKPT-SEEQSMAPIF-----VEKLRPKHTPDGSTVQFECQVEGY--PRPQI 541
E ++ + E P +E ++ AP++ ++ K +G V FE + PR Q+
Sbjct: 2303 ESWKRIQILEAPKEAEPEAPAPVYDHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQV 2362
Query: 542 TWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV- 600
W R + + + D + TL + +PED G + N G A S+ L
Sbjct: 2363 QWIRNGVPLAHGSKYAIQ-QDFGICTLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCH 2421
Query: 601 --EAPLSD---HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLE 654
+A L D S + AD PP F ++ + E E
Sbjct: 2422 GKDAILGDVQHQESWKRIQEIEAPKQKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFE 2481
Query: 655 CRLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
+ + +P I W GE + + + +D ++ I + G + VA
Sbjct: 2482 ATVEPVDDPTLTINWFLNGEPMSASSRVKMI--NDFGWV--IMDIAQTEPRDSGEWKCVA 2537
Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
N GEA ++++ E ++P +RQ E+
Sbjct: 2538 KNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEA 2576
Score = 38.7 bits (86), Expect = 0.045
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 731 EKEPPQVIEPLKSMI--VRQGESVILSAQVVGNPRPTIT--WCKNNKPVKALPTKSDGDT 786
EKE P + +PL + I V + +++ L AQV T+ W N P+KA +
Sbjct: 1134 EKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKASSRYRVLND 1193
Query: 787 HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE 823
L + +D G YTL NS G AETS V+
Sbjct: 1194 FGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1232
Score = 38.7 bits (86), Expect = 0.045
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PE T+LQN V +G FE ++ D V WFKD + + + T+D L
Sbjct: 3240 PEFRTQLQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACL 3299
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
+ DD GEY C N
Sbjct: 3300 DLLYALPDDTGEYHCVATN 3318
Score = 37.9 bits (84), Expect = 0.078
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
+P + W N I S I+ + L+I ++ + D+G+YKCVA+N G ++
Sbjct: 3027 DPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAA-DAGEYKCVATNVKGSATSV 3085
Query: 919 ARVTID----VEKVTFVKHLQKSYET-EEGKTVILECQTS 953
++ ++ ++ V+ L S E EG ++ LEC+ +
Sbjct: 3086 GKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVT 3125
Score = 37.5 bits (83), Expect = 0.10
Identities = 19/79 (24%), Positives = 37/79 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P V+W +GN+L ++ +Y T + + I + + S Y+ A N G S + T
Sbjct: 396 PDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSNDSGLYSCRAFNKLGESENQAT 455
Query: 1660 LKVYDKPSKPEGPVIMREI 1678
+ ++ S+ P + +I
Sbjct: 456 IIIFAHSSQDLTPKFLSQI 474
Score = 37.5 bits (83), Expect = 0.10
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNN 772
E EA P + PP+ L +++G+ L QV V +PR I W N
Sbjct: 2843 EIEAPRPAREDAPDADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNG 2902
Query: 773 KPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+PV K+ D + + L P + +D G +T +A N G E S + V
Sbjct: 2903 QPVNHTNRMKAIHDFGFVVLQLTPAEPQDSGTWTCRATNQHGSDEVSTELKV 2954
Score = 37.1 bits (82), Expect = 0.14
Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 1107 PEIITRLQNQ-KVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
P I+ LQ Q + +G A + + T V W KDG I SN ++ D
Sbjct: 2592 PAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHSNRYKMVHDFGFAV 2651
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIP 1221
L I DAGEY+ V N+ A S +F + IL P N VEI
Sbjct: 2652 LDILHLLKHDAGEYTFRVSNNSGEA-----STSTSFEVSESSGLILQPQNEQKAKAVEIL 2706
Query: 1222 DETL 1225
++ L
Sbjct: 2707 EDNL 2710
Score = 36.3 bits (80), Expect = 0.24
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDGD 785
+PP E L ++G+S+ L ++ V +P +TW +N +P+ + +P ++ D
Sbjct: 1402 QPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPLPEASRFMPARNF-D 1460
Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++ IL +D GVYT KA ++ G A TS +
Sbjct: 1461 YVNLDILALYG-EDSGVYTCKAVSAFGEAATSCTV 1494
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P + W+K+G L N + +TT + I S Y+++ASN G + V+
Sbjct: 1698 PNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQ 1757
Query: 1660 LKV 1662
L V
Sbjct: 1758 LTV 1760
Score = 36.3 bits (80), Expect = 0.24
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
+P ++ A P F + + V E + VT P P +TW+ N NF
Sbjct: 3369 QPKQKQA--PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNF 3426
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
DG + + + D+G+ +A N+ G++ A + I
Sbjct: 3427 DG--LHYLTVSKSRISDAGEVVAIARNTEGETISTATLDI 3464
Score = 35.9 bits (79), Expect = 0.32
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870
+ E E+P E+ + P FI I E + +VT P+ I W+++
Sbjct: 1650 VLEAPRAAAPEKPDAEH-DAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDG 1708
Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ + S D I L I + E DSG Y ASN+ G + A++T+
Sbjct: 1709 QPLMNSNRFKLTTDFGYISLDIAHTVPE-DSGVYSVKASNAKGDAEVQAQLTV 1760
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P +V W K+G + + Y + +V+ I L + + +YT SN +G +S +
Sbjct: 2622 PSIKVEWLKDGQPIFHSNRYKMVHDFGFAVLDILHLLKHDAGEYTFRVSNNSGEASTSTS 2681
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIE 1686
+V S+ G ++ + +++ +E
Sbjct: 2682 FEV----SESSGLILQPQNEQKAKAVE 2704
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASL 1345
PK + ++ G L + Y PN W++N K I D A+L
Sbjct: 239 PKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILASSRIVTFTDFGIAAL 298
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
I V D G Y + N G A V N+ ++
Sbjct: 299 EINPVNVFDQGEYTVVAVNPLGEARVSANIAVI 331
Score = 33.1 bits (72), Expect = 2.2
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 1106 PPEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
PP+ +T+L + V +G + FE I + V+W+ +G+ + S+ L D
Sbjct: 1799 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 1858
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK 1184
L + +DAGEYS V NS+
Sbjct: 1859 SLDLQYTLGEDAGEYSVVVKNSE 1881
Score = 32.7 bits (71), Expect = 3.0
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 7/116 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKN 771
R+ EA P + + E P ++ L+ + +G S L Q V +P + W K+
Sbjct: 2572 RQIEAGKPAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKD 2631
Query: 772 NKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
+P+ D + IL K D G YT + N+ G A TS V E
Sbjct: 2632 GQPIFHSNRYKMVHDFGFAVLDILHLLK-HDAGEYTFRVSNNSGEASTSTSFEVSE 2686
Score = 32.3 bits (70), Expect = 3.9
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 735 PQVIEPLKSMIVRQGES--VILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITI 791
P+ + L + + + E+ V L A V +P I W N +P+ K+ + I +
Sbjct: 740 PKFLNDLPDIQLNEHENIHVDLRATPVNDPTMVIEWFVNGRPLLTGSRVKTLNEFGFIAL 799
Query: 792 -LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+K +D G Y+++A N G A VITV
Sbjct: 800 DIKGAIAEDSGTYSVRASNLLGEAIRQCVITV 831
Score = 32.3 bits (70), Expect = 3.9
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTIT--WCKN 771
+E EA P ++ +PP ++ L I +G++V L AQV ++T W N
Sbjct: 986 QEIEAPKPAPQEVPDLPHQPPAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVN 1045
Query: 772 NKPV-KA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
+P+ KA D ++ IL +D G YTL N G A+++ I
Sbjct: 1046 GQPLMKAHRFVLSQDFGYIALNILYCYP-EDNGTYTLVVRNRAGEAQSTVDI 1096
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
+A ++G P P V W G + I+ K +++ + + + +Y I N G
Sbjct: 4132 SAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQIVIRNDKG 4191
Query: 1653 --TSSVEVTL 1660
TS ++TL
Sbjct: 4192 AATSQAKLTL 4201
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/66 (24%), Positives = 29/66 (43%)
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
Q P +W + + + K + D SL I D+G+Y ++ N G A+V
Sbjct: 1695 QTDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEV 1754
Query: 1372 EMNVTI 1377
+ +T+
Sbjct: 1755 QAQLTV 1760
Score = 31.1 bits (67), Expect = 9.0
Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ G P P+V W+ NGN+ + + + + + + + + S + + A NT G +
Sbjct: 3399 VTGYPRPKVTWFINGNQCLHGHRFKLNF-DGLHYLTVSKSRISDAGEVVAIARNTEGETI 3457
Query: 1656 VEVTLKVY 1663
TL ++
Sbjct: 3458 STATLDIF 3465
>AF106579-1|AAC78200.4| 4889|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform a protein.
Length = 4889
Score = 113 bits (271), Expect = 2e-24
Identities = 113/458 (24%), Positives = 188/458 (41%), Gaps = 64/458 (13%)
Query: 500 KPTSEEQSMA--PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
+PT QS P ++L+P G +F + G ++TW + IK +
Sbjct: 4460 QPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTL 4519
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ N ++L I + AG +T +NAAG S L V P +
Sbjct: 4520 ITTTPTN-SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTT------------ 4566
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
+G P FS + + + C++ P+P I W G+ + D
Sbjct: 4567 ------------QGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPND 4614
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---KTGEK-- 732
+ V E + LK +N+ G Y +VA N GEA L + KTG+
Sbjct: 4615 DRFQVVEEGGAYK----LKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAE 4670
Query: 733 -----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
E P+ ++ ++V +G+ SAQ G P PTI W +NN+PVK +
Sbjct: 4671 EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSK 4730
Query: 788 SITILKPKKVKDEGV--YTLKAENSEGIAETSA--VIT------------------VEEP 825
IL+ ++E V Y ++A N G A + A V+T +
Sbjct: 4731 GEAILRISAARNEDVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSS 4790
Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
+ A+ P FI + +I+ ++ T+K A V NP P++ W + IS S + + DG
Sbjct: 4791 DKAAADSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDG 4850
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ L + V + +G+Y+ V N G ++ A++T+
Sbjct: 4851 KRAILELARVTPD-SAGEYQIVIRNDKGAATSQAKLTL 4887
Score = 95.5 bits (227), Expect = 4e-19
Identities = 69/226 (30%), Positives = 103/226 (45%), Gaps = 14/226 (6%)
Query: 498 FEKPTSEEQS---MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
F++P E + +AP F+ L K G T+ ECQ+EG+P P I W + +
Sbjct: 3 FKQPLGERDAANRVAPTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSMCP 62
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI-VEAPLSDHGSEMTV 613
D+++ +D LVI +V D+G FT A N+AG ST LI AP G++ V
Sbjct: 63 DYRI-EEDGLKHRLVIPQVQAADSGRFTAQASNSAGTKQSTCILICAPAPTPVPGAKSAV 121
Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
+ P F K+ + Q + G+ + E R++A+P P+I W+ G+
Sbjct: 122 ASPAPPQTPVGPS------APIFLKELRHQPLKPGAGVTFEGRVIAVPPPNIEWMKNGK- 174
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
P +N IE D L I + G YT+ A N GEA
Sbjct: 175 --PLQNYRAKIEHDQKTGIISLIIPQMFNDDAGEYTIKATNVHGEA 218
Score = 84.2 bits (199), Expect = 9e-16
Identities = 64/272 (23%), Positives = 121/272 (44%), Gaps = 18/272 (6%)
Query: 722 PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
P KI ++ PP + + LK + G++ + G +TW K+ K +K+
Sbjct: 4459 PQPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRT 4518
Query: 782 SDGDTHSITILKPKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
T + + L ++++ G YT++ EN+ G E+ A +TV PT + P F R
Sbjct: 4519 LITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPD-FSARL 4577
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ +++ G + ++ P P+I W+++ + + + +G +L +N+ S
Sbjct: 4578 NDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIIS-T 4636
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE------------TEEGKTVI 947
D+G Y+ VA N G++ AR+ ++++K YE +EGK
Sbjct: 4637 DAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQ 4696
Query: 948 LECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977
Q S + +WY N + + D EI Q
Sbjct: 4697 FSAQFSGFPDPTIRWYRNNEPVKHADGYEISQ 4728
Score = 76.6 bits (180), Expect = 2e-13
Identities = 53/195 (27%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSI 789
PPQ + +S+ + E+V SA+VVG P P++TW K++ V ++ D
Sbjct: 705 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGR 764
Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
I++ D +Y L A N G ++ + V + ++ E P F +FQ T+ + +
Sbjct: 765 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQ--AKSPEAPEFTGKFQSTTLYDGDS 822
Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
+KL + V S W+++NE IS + + G L I N + + G Y+C A+
Sbjct: 823 VKLYCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMK-EGGWYRCDAT 880
Query: 910 NSAGKSSHGARVTID 924
N G ++ RV ++
Sbjct: 881 NKHGTTTLKGRVVVN 895
Score = 66.1 bits (154), Expect = 3e-10
Identities = 119/539 (22%), Positives = 206/539 (38%), Gaps = 81/539 (15%)
Query: 474 LMDENNYTQYLQKKLN-EKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFEC 531
L+ + ++ LQK E IDK + P E + P +V+ ++ +G TV
Sbjct: 2752 LLLDTSHPASLQKIQELEAIDKYARLDAPEREYEK--PQWVQGFENYENVGEGQTVTLHG 2809
Query: 532 QVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
VE G P ++ W ++ + F+ Y+ N A L I V P D+G +TC A N
Sbjct: 2810 LVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN-AILTIVHVLPHDSGVYTCRAWNTQ 2868
Query: 590 GFASSTTELIV---EAPLSDHGSEMT---VXXXXXXXXXXXXADILEGIPPTF-SKKPKA 642
G AS++ + E L D ++ + +I++ P F ++ A
Sbjct: 2869 GEASTSATVTTAGYEKILYDSQHPVSWERIQELEAPKIVEEIEEIVQKEKPNFLTQLESA 2928
Query: 643 QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDE-----------NISVAIESDMH 689
+ V EG + LE +P+ + W G+ + + + ++ ++ H
Sbjct: 2929 ENVPEGVPLHLESTFQPARDPELKVVWQKNGQPLGASQLVQTKHELGWATLDISSANEDH 2988
Query: 690 MYCSVLKITNVKKFQ--------EGTYTVVAVNREGEASLPIVLKIKTGEKEP------- 734
L ITN + GT ++ R E+ I + E EP
Sbjct: 2989 NGVYTLTITNSEGEAVSTASIRVAGTGPILGNTRHEESWKRIQILEAPKEAEPEAPAPVY 3048
Query: 735 --PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
P + + +G+ V A + V +PR + W +N P+ + I
Sbjct: 3049 DHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQVQWIRNGVPLAHGSKYAIQQDFGIC 3108
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVI----------------------TVEEPT 826
L +DEGVY L+ N EG A +SA + +E P
Sbjct: 3109 TLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCHGKDAILGDVQHQESWKRIQEIEAPK 3168
Query: 827 EENAE-------PPLFINRFQ---EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
++ E PP FI + + + + +P +I W+ N E +S S
Sbjct: 3169 QKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSAS 3228
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
+ D + + I + DSG++KCVA N+AG++ A + + ++V LQ
Sbjct: 3229 SRVKMINDFGWVIMDIAQTEPR-DSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQ 3286
Score = 65.7 bits (153), Expect = 3e-10
Identities = 58/222 (26%), Positives = 89/222 (40%), Gaps = 28/222 (12%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
D + PTF + + G I+LEC+L P+P I WL G + + + +
Sbjct: 11 DAANRVAPTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSMCPDYRIEEDG 70
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL------------KIKTGEKEP 734
H L I V+ G +T A N G +L K P
Sbjct: 71 LKHR----LVIPQVQAADSGRFTAQASNSAGTKQSTCILICAPAPTPVPGAKSAVASPAP 126
Query: 735 PQV---------IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785
PQ ++ L+ ++ G V +V+ P P I W KN KP++ K + D
Sbjct: 127 PQTPVGPSAPIFLKELRHQPLKPGAGVTFEGRVIAVPPPNIEWMKNGKPLQNYRAKIEHD 186
Query: 786 --THSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITVEE 824
T I+++ P+ D+ G YT+KA N G A + A + E
Sbjct: 187 QKTGIISLIIPQMFNDDAGEYTIKATNVHGEAISGAQLLPRE 228
Score = 64.1 bits (149), Expect = 1e-09
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 23/248 (9%)
Query: 500 KPTSEEQS-MAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQ 554
KP+ ++ + P+F ++L P +G +V +C V+ P +I WF +
Sbjct: 1982 KPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGS 2041
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDH- 607
+ +D V L + PED GT+TC A N G +TT++ +E L H
Sbjct: 2042 RIRTIHDFGYVG-LEFLHIHPEDTGTYTCKATNLIG--EATTDIFLECKPRRNIYLDTHH 2098
Query: 608 -GSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD- 664
S + L PPTF++ + EG I LECRL+ + +P
Sbjct: 2099 ESSWQKIQEIENRVDEREPTPELTFQPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTM 2158
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+ W G+ + A D Y + L I + G YT AV+ GEA+
Sbjct: 2159 RVTWTRNGQPLPEASRFMPARNFD---YVN-LDILALYGEDSGVYTCKAVSAFGEAATSC 2214
Query: 724 VLKIKTGE 731
+K G+
Sbjct: 2215 TVKCAAGK 2222
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/209 (24%), Positives = 90/209 (43%), Gaps = 24/209 (11%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITI 791
P I PL GE++IL Q+ G+P P I W K+ V P + DG H + +
Sbjct: 18 PTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSMCPDYRIEEDGLKHRL-V 76
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVI--------------TVEEP----TEENAEPP 833
+ + D G +T +A NS G +++ ++ V P T P
Sbjct: 77 IPQVQAADSGRFTAQASNSAGTKQSTCILICAPAPTPVPGAKSAVASPAPPQTPVGPSAP 136
Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVI 892
+F+ + +K + RV P P+I W +N + + I + I L+I
Sbjct: 137 IFLKELRHQPLKPGAGVTFEGRVIAVPPPNIEWMKNGKPLQNYRAKIEHDQKTGIISLII 196
Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARV 921
+ ++ D+G+Y A+N G++ GA++
Sbjct: 197 PQMFND-DAGEYTIKATNVHGEAISGAQL 224
Score = 63.3 bits (147), Expect = 2e-09
Identities = 78/409 (19%), Positives = 161/409 (39%), Gaps = 29/409 (7%)
Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP-QPNDEWIVNSKIIK 1329
LD + ++K++ + P + D E ++K ++ + + Q P QP +E IV+ ++
Sbjct: 4357 LDVPARDQVKLKTAK-PTRGKDLEAGEKVKLKTEKAKIKEIQQKPEQPKEEPIVHKDAVQ 4415
Query: 1330 KCKHTKPSIDSKSASLTI---KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
P K T+ K ++ T A + + E + + + P
Sbjct: 4416 LKTQQLPKTGIKGDHFTVDREKDLKETPAVVKPVIEETRISNKPQPTKIGQSKQAPPTIS 4475
Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
+ + E G + + + ++ + +EI +T + ++ T T +S+ +
Sbjct: 4476 QQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKST-FRTLITTTPTNSSLHIGRL 4534
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKET-KIQSPTVEKPLKNITTEPNEDIELTCI 1504
+S+ Y V + + E+ V T + ++P L ++ + N E +C
Sbjct: 4535 ENSHAGE-YTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQ 4593
Query: 1505 FGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVE 1560
GG P+P + W++DG+ L + E Y+ +A N GE
Sbjct: 4594 IGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEAR 4653
Query: 1561 TSCVVGIQ--------------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
+ + + P T + I G ++ +A G P P + W
Sbjct: 4654 CKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQF--SAQFSGFPDPTIRW 4711
Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
Y+N +++ Y I+ + +++RI + ++Y +EASN AG +S
Sbjct: 4712 YRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKAS 4760
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/319 (22%), Positives = 119/319 (37%), Gaps = 27/319 (8%)
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
+ PP I +L+ + G A F IE + V W KDG EI+ + +T
Sbjct: 4469 QAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSS 4528
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCT----AILTVEEPSI-----NFTLRLPEFILVPANTD 1213
L I + AGEY+ + N+ T A LTV P+ +F+ RL + + + N
Sbjct: 4529 LHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLND-LRIQQNGP 4587
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271
A + +I E + W+K + + ++F ++ + L D Y V
Sbjct: 4588 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4647
Query: 1272 ---DAKSTTKLKVEVV-------EFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+A+ +L V + E P P+ + + G + FP P
Sbjct: 4648 GVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDP 4707
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W N++ +K + S A L I N D YK+ N G A N+ +
Sbjct: 4708 TIRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVL 4767
Query: 1378 LDKPSPPGKPNILEIDSSS 1396
+ K I S+S
Sbjct: 4768 TPRSGRIAKSTISRGGSAS 4786
Score = 62.1 bits (144), Expect = 4e-09
Identities = 83/338 (24%), Positives = 135/338 (39%), Gaps = 32/338 (9%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
P F L P +G ECQV PR I WF + + + +D V
Sbjct: 3584 PKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIHDFGFVV 3643
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---------PLSDHGSEMT-VXXX 616
L + P+D+GT+TC A N G +TEL V ++ +T +
Sbjct: 3644 -LQLTPAEPQDSGTWTCRATNQHGSDEVSTELKVVGGGGVSYEWQSTAERKERITELEDW 3702
Query: 617 XXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
++ P+FS+ ++E C L I +P + W G
Sbjct: 3703 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHP 3762
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK- 732
I IS E + + L I ++ G Y VA N +G A+ + +++ +
Sbjct: 3763 IPYSNRISCTNEFGV----ATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQI 3818
Query: 733 EPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDG 784
+ PQV++ L + + +G+S+ L +V + +PR + W +N P+ + PT G
Sbjct: 3819 DAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFG 3878
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S+ IL +D G Y L N +G A + ITV
Sbjct: 3879 FV-SLDILYAYP-EDNGDYELVVRNDKGEARSKTKITV 3914
Score = 60.1 bits (139), Expect = 2e-08
Identities = 57/222 (25%), Positives = 91/222 (40%), Gaps = 17/222 (7%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F K + DG +V+ C+ G WF+ I + + + N TL
Sbjct: 805 APEFTGKFQSTTLYDGDSVKLYCKAAG-EGVSFKWFKDNEPISSGGSYAVD-NKGNETTL 862
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS---EM-TVXXXXXXXXXXX 624
I ++ G + C A N G + ++V + +G EM T+
Sbjct: 863 HINNATMKEGGWYRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREMITLRKVDKVERSRT 922
Query: 625 XADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPD 677
+ L+ + P F ++Q + EG LE + + +P+ IAWL G+ I+
Sbjct: 923 PVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILAS 982
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I + + + L+I V F +G YTVVAVN GEA
Sbjct: 983 SRIVTFTDFGI----AALEINPVNVFDQGEYTVVAVNPLGEA 1020
Score = 55.6 bits (128), Expect = 4e-07
Identities = 51/192 (26%), Positives = 81/192 (42%), Gaps = 15/192 (7%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDG 885
NA PP F+ Q + K T+ A+V P PS+TW +++ + S I DG
Sbjct: 702 NARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDG 761
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV------EKVTFVKHLQKSYE 939
L+I VD+ D+ Y VA N G S +R +++V E F Q S
Sbjct: 762 SG-RLIIEKVDAH-DADMYMLVARNDGG--SFQSRFSLNVLQAKSPEAPEFTGKFQ-STT 816
Query: 940 TEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
+G +V L C+ + VS KW+ + + IS + +G + G +
Sbjct: 817 LYDGDSVKLYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYR 876
Query: 999 CIVKDQETSTML 1010
C ++ +T L
Sbjct: 877 CDATNKHGTTTL 888
Score = 55.2 bits (127), Expect = 5e-07
Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILK 793
P + PL+ + + +G IL A +VGNP+P I W N +P++ P S+ +LK
Sbjct: 303 PIIRTPLRGLRLTEGTDAILQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTYKGSMAVLK 362
Query: 794 PKKVKDE--GVYTLKAENSEGIAETSAVITV 822
V E G YT+ +EN G E+SA I V
Sbjct: 363 ISMVTTEEAGDYTVASENRFGKVESSARIEV 393
Score = 54.8 bits (126), Expect = 6e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 6/94 (6%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN---V 565
APIF+++LR + G+ V FE +V P P I W + KP Q+++ + D +
Sbjct: 135 APIFLKELRHQPLKPGAGVTFEGRVIAVPPPNIEWMKNG---KPLQNYRAKIEHDQKTGI 191
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
+L+I ++F +DAG +T A N G A S +L+
Sbjct: 192 ISLIIPQMFNDDAGEYTIKATNVHGEAISGAQLL 225
Score = 54.8 bits (126), Expect = 6e-07
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+Q AP F LR + +FEC V GYPRP++TWF F++ +D +
Sbjct: 4093 KQKQAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLH 4152
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
T+ + DAG +A+N G ST L
Sbjct: 4153 YLTVSKSRI--SDAGEVVAIARNTEGETISTATL 4184
Score = 54.8 bits (126), Expect = 6e-07
Identities = 53/230 (23%), Positives = 90/230 (39%), Gaps = 19/230 (8%)
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
+ E IS+ + T+ I ++K PT+ + LK + E + + F G KVTW
Sbjct: 4450 IEETRISNKPQPTK----IGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTW 4505
Query: 1516 YRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
+DGK++K T T Y N G VE+ + +
Sbjct: 4506 LKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPT 4565
Query: 1569 ---QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
+ P + D++ + E+ + I G P P + W+K+G L ND + + +
Sbjct: 4566 TQGKAPDFSARLNDLRIQQNGPAEF--SCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEG 4623
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSK--PEGP 1672
++ + + + Y I A N G + + L V K K EGP
Sbjct: 4624 GAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4673
Score = 53.2 bits (122), Expect = 2e-06
Identities = 56/223 (25%), Positives = 85/223 (38%), Gaps = 17/223 (7%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P F+++L P + FE VE P +T WF + S +M +D
Sbjct: 3182 PRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMI-NDFGWV 3240
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTT-------ELIVEAPLSDHGSEMTVXXXXXX 619
+ I + P D+G + CVAKNAAG A ST E+I++ L +
Sbjct: 3241 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEAGK 3300
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVPD 677
D P + ++EG L+ + + +P I WL G+ I
Sbjct: 3301 PAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHS 3360
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
+ + +VL I ++ K G YT N GEAS
Sbjct: 3361 NRYKMVHDFGF----AVLDILHLLKHDAGEYTFRVSNNSGEAS 3399
Score = 52.8 bits (121), Expect = 3e-06
Identities = 59/241 (24%), Positives = 93/241 (38%), Gaps = 17/241 (7%)
Query: 491 KIDKLPVFEKPTSEEQSMA-----PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITW 543
K+DK+ P ++ Q ++ P F L+ + +G + + E + P +I W
Sbjct: 913 KVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAW 972
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
I S + + D +A L I V D G +T VA N G A + + V
Sbjct: 973 LLNGKGILASSRI-VTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGEARVSANIAVIGH 1031
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIP---PTFSKKPKAQYVDEGSDILLECRLVAI 660
S + + A G P F ++Q V EG I LE +L I
Sbjct: 1032 GSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKLTPI 1091
Query: 661 PEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+PD + WL G E+ ++ + H + S L I G Y+ A N+ GE
Sbjct: 1092 NDPDLRVVWLLDGNELPSNDKYRQTLS---HGFAS-LDIPQTSSNDSGLYSCRAFNKLGE 1147
Query: 719 A 719
+
Sbjct: 1148 S 1148
Score = 52.0 bits (119), Expect = 5e-06
Identities = 64/265 (24%), Positives = 102/265 (38%), Gaps = 22/265 (8%)
Query: 470 PAQYLMDENNYTQYLQK-KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGST 526
PA ++ + + + L K E ++K E Q P FV L+ +G
Sbjct: 1555 PAGQILSDTQHQESLGKINYLENLNKYGRVEIEDKGPQE-PPTFVVPLQADLGDVEEGEP 1613
Query: 527 VQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
+ ECQV +I W R + F+ +YD V+ L I + +DAGT+TC
Sbjct: 1614 IHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFYDFGFVS-LDILGFYAQDAGTYTCR 1672
Query: 585 AKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
A+N+ G A + + + + S + L PP F K
Sbjct: 1673 AENSLGQAETVATIRCAPKDAILGAVQHPRSYARIQEIEAPKPAPQEVPDLPHQPPAFVK 1732
Query: 639 K--PKAQYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSV 694
+ P Q + EG ++ LE ++ + + WL G+ ++ + D
Sbjct: 1733 QLGPAIQCM-EGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRF--VLSQDFGYI--A 1787
Query: 695 LKITNVKKFQEGTYTVVAVNREGEA 719
L I GTYT+V NR GEA
Sbjct: 1788 LNILYCYPEDNGTYTLVVRNRAGEA 1812
Score = 51.6 bits (118), Expect = 6e-06
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 1191 VEEPSINFTLRLPEF-ILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISD 1247
V+ P+ +F+ L + L A+ A++ V P D TL V W I + + + ++
Sbjct: 3715 VDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNE 3774
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP-----PKIVDY--EREYRI 1299
TL+I+ D EY CV + K S T + VE P++V + I
Sbjct: 3775 FGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENI 3834
Query: 1300 KRGSDVTLLVDYQAFPQP--NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
G + L P + EW+ N + + KP+ + SL I D G
Sbjct: 3835 LEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFVSLDILYAYPEDNGD 3894
Query: 1358 YKLRLENNCGHADVEMNVTILDKPS 1382
Y+L + N+ G A + +T+L +PS
Sbjct: 3895 YELVVRNDKGEARSKTKITVLPRPS 3919
Score = 50.8 bits (116), Expect = 1e-05
Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 23/273 (8%)
Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR-PKHTPDGSTVQFECQ 532
L +N + L + + + P E+ E + P+F+E L P T +G F +
Sbjct: 3414 LQPQNEQKAKAVEILEDNLRRRP--EEIEQELKEATPVFIEPLSAPVETEEGGRAHFTAR 3471
Query: 533 VEGYP--RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
E + Q+ W+ +K + + L I +PED G + C A N G
Sbjct: 3472 YEPVNDNQLQVQWYHDGRPLKNGSRIKTI-NSFGYVVLEISPTYPEDNGEYICRAVNRVG 3530
Query: 591 FASSTTEL-------IVEA---PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKK 639
A ++T+L I+ A P + + A + PP F S
Sbjct: 3531 EAVTSTKLTCTPKEGIISATQLPERMANAGRRIAEIEAPRPAREDAPDADHGPPKFTSAL 3590
Query: 640 PKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
+ EG LEC++ + +P I W G+ + N + +++ VL++
Sbjct: 3591 AGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPV----NHTNRMKAIHDFGFVVLQL 3646
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730
T + GT+T A N+ G + LK+ G
Sbjct: 3647 TPAEPQDSGTWTCRATNQHGSDEVSTELKVVGG 3679
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816
+G+P + W N P+ S + + L K + D G Y A N +G A +
Sbjct: 3747 IGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATS 3806
Query: 817 SAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVT--RNPVPSITWYRNNEII 873
I VE T+ +A P + + + E +I L RVT +P + W RN +
Sbjct: 3807 VGKIAVESSTQIDA-PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPL 3865
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ F+ + L I E D+GDY+ V N G++ ++T+
Sbjct: 3866 PEASRFKPTFEFGFVSLDILYAYPE-DNGDYELVVRNDKGEARSKTKITV 3914
Score = 48.4 bits (110), Expect = 6e-05
Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 20/243 (8%)
Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
E+P AP F +L K + V FE ++ + + W+ + +
Sbjct: 1317 ERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAAHR 1376
Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP----LSDHGSE- 610
F +D VA L + +P+D+GT+T VA+N G A S EL+V L H E
Sbjct: 1377 FHPMFDFGYVA-LDLLYAYPQDSGTYTLVARNELGEARSNVELVVGTEKVLYLEPHHPEG 1435
Query: 611 MTVXXXXXXXXXXXXADI----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD-- 664
+ A++ + P + P Q ++E +I ++ R + +P
Sbjct: 1436 LERIKELEQDRRQGIAEVEDRTCDAAPKFLNDLPDIQ-LNEHENIHVDLRATPVNDPTMV 1494
Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
I W G ++ + E L I GTY+V A N GEA V
Sbjct: 1495 IEWFVNGRPLLTGSRVKTLNEFGF----IALDIKGAIAEDSGTYSVRASNLLGEAIRQCV 1550
Query: 725 LKI 727
+ +
Sbjct: 1551 ITV 1553
Score = 46.8 bits (106), Expect = 2e-04
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMH 689
G P + + EG+D +L+ +V P+P I WLF G + V + + + M
Sbjct: 300 GTKPIIRTPLRGLRLTEGTDAILQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTYKGSM- 358
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+VLKI+ V + G YTV + NR G+
Sbjct: 359 ---AVLKISMVTTEEAGDYTVASENRFGK 384
Score = 46.4 bits (105), Expect = 2e-04
Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 506 QSMAPIFVEKLRPKHTPDG-STVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDD 562
Q + P F+ +++P H FE +++ P +++W + + + Q++ +
Sbjct: 1186 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIF-QN 1244
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
V +L + +PEDAG +TCV N+ G A S+ EL
Sbjct: 1245 FGVVSLSLHPTYPEDAGVYTCVLFNSHGQAQSSAEL 1280
Score = 46.0 bits (104), Expect = 3e-04
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 11/157 (7%)
Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQVV--GNPRPTITWCKNNKPVKA---LPTKSDGDT 786
E P ++PL+S+ + +G +L A++V +P + W N++P+ + T +D
Sbjct: 2652 EKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMESNWISTSNDFGC 2711
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITV 844
S+ I P + GVY+ KA N G A TSA + V+ E + P + + QE+
Sbjct: 2712 VSLRIA-PVYARHTGVYSCKAWNDSGNAVTSANVGVQGSEGLLLDTSHPASLQKIQELEA 2770
Query: 845 KEKGTIKLVARVTRNPVPS-ITWYRNNEIISPSETIT 880
+K +L A P + + N E + +T+T
Sbjct: 2771 IDK-YARLDAPEREYEKPQWVQGFENYENVGEGQTVT 2806
Score = 46.0 bits (104), Expect = 3e-04
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L+++NVKK + Y + +G A P +K+ PQ PL+++ V + +
Sbjct: 4069 LRVSNVKKDNKNIYW----SEQGGAVQP-------KQKQAPQFTIPLRNLQVTENQPARF 4117
Query: 755 SAQVVGNPRPTITWCKN-NKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENSEG 812
V G PRP +TW N N+ + K + D H +T+ K ++ D G A N+EG
Sbjct: 4118 ECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSK-SRISDAGEVVAIARNTEG 4176
Query: 813 IAETSAVITV 822
++A + +
Sbjct: 4177 ETISTATLDI 4186
Score = 45.6 bits (103), Expect = 4e-04
Identities = 55/231 (23%), Positives = 89/231 (38%), Gaps = 18/231 (7%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDF 556
EKP +E AP F+E L + + F+ +V + P +I WF+ + S F
Sbjct: 2382 EKPDAEHD--APQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRF 2439
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMT- 612
++ D ++ L I PED+G ++ A NA G A +L V L D E +
Sbjct: 2440 KLTTDFGYIS-LDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTVTGNAVILGDTQHEQSW 2498
Query: 613 ---VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAW 667
D+ G P ++ V EG E + + +P + W
Sbjct: 2499 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 2558
Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
G + + + +D + L+ T + G Y+VV N EGE
Sbjct: 2559 YLNGNPL--SASSRRILRNDFGLVSLDLQYTLGE--DAGEYSVVVKNSEGE 2605
Score = 44.8 bits (101), Expect = 7e-04
Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 17/197 (8%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE- 601
W +K S +++ +D +L I + ED+G +T V N+AG A ++ E V+
Sbjct: 1897 WLFNGNPLKASSRYRVL-NDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVDR 1955
Query: 602 --APLSD--HGSEM-TVXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLE 654
+ LSD H + + D PP F+++ + + EG + ++
Sbjct: 1956 LKSILSDTAHPESLRRIREMEQLQPAKPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMD 2015
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVV 711
C + I +P I W G ++ I +H + V L+ ++ GTYT
Sbjct: 2016 CVVQPINDPSLRIEWFHDGRPLMFGSRIRT-----IHDFGYVGLEFLHIHPEDTGTYTCK 2070
Query: 712 AVNREGEASLPIVLKIK 728
A N GEA+ I L+ K
Sbjct: 2071 ATNLIGEATTDIFLECK 2087
Score = 44.8 bits (101), Expect = 7e-04
Identities = 63/285 (22%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
K+ P ++L+ + + A +E + V W +DG+ IK +
Sbjct: 4468 KQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTN- 4526
Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE-----LPPEIITRLQNQKVNKGN 1122
L+I GEY+ L + + T E +TV P+ RL + ++ +
Sbjct: 4527 SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNG 4586
Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
A F ++ + ++WFKDG + + Q+ +G KLK + DAG Y
Sbjct: 4587 PAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAK 4646
Query: 1179 -EVGNSKCTAILTV----------EEP---SINFTLRLPEFILVPANTDAYLTVE---IP 1221
VG ++C A L V E P + FT ++ + I+V A + + P
Sbjct: 4647 NGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQI-QPIVVDEGKGAQFSAQFSGFP 4705
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
D T + WY+ ++ + + + + L I +D EY
Sbjct: 4706 DPT--IRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEY 4748
Score = 44.4 bits (100), Expect = 0.001
Identities = 23/86 (26%), Positives = 42/86 (48%)
Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
VG+ ++ +EG P P + W K+G+ + +Y I + I +++ + S ++T
Sbjct: 31 VGETIILECQLEGHPDPAIKWLKDGHNVSMCPDYRIEEDGLKHRLVIPQVQAADSGRFTA 90
Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEG 1671
+ASN+AGT L P+ G
Sbjct: 91 QASNSAGTKQSTCILICAPAPTPVPG 116
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 25/223 (11%)
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD----VAILEVEINSETADVVWERDGE 1054
I + +E + V P F + L D ++ E D V +LE I T V WE +G
Sbjct: 3703 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLE-PIGDPTLRVQWEHNGH 3761
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELP----- 1106
I P N+ + L I++ D GEY C+ ++ + + VE
Sbjct: 3762 PI-PYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDA 3820
Query: 1107 PEIITRLQNQKVN--KGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
P+++ +L + N +G+ E +T D V W ++G+ + ++ + T +
Sbjct: 3821 PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFV 3880
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK-----CTAILTVEEPSINFT 1199
L I +D G+Y V N K T I + PS+++T
Sbjct: 3881 SLDILYAYPEDNGDYELVVRNDKGEARSKTKITVLPRPSLDYT 3923
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P I +L + +G+ F E+ + V+W G I SN+++++ DGK+ L++
Sbjct: 4798 PHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILEL 4857
Query: 1166 YDCDLDDAGEYSCEVGNSKCTA 1187
D AGEY + N K A
Sbjct: 4858 ARVTPDSAGEYQIVIRNDKGAA 4879
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGSTVQFECQVEGYPRPQIT--WFR 545
++I+ E +E + AP FV +L +G + E QVE Q+T WF
Sbjct: 2238 QEIENREKLEAVDAEPEKTAPKFVTQLNSSLGELQEGVPIHLEAQVEPTNDNQLTVQWFH 2297
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ F+ +D VA L I F +D G + CVA+N+ G A + V
Sbjct: 2298 NGQPLANGHRFRTRHDFGYVA-LDILYAFAQDTGEWACVARNSLGEAQTIANFTV 2351
Score = 43.6 bits (98), Expect = 0.002
Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 24/247 (9%)
Query: 490 EKIDKLPVFEKPTSEEQSMA---PIFVEKLRPKH-TPDGSTVQFECQVEGY--PRPQITW 543
+KI + P EE + P FV +L +G FE Q + P+ + W
Sbjct: 2499 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 2558
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-- 601
+ + S ++ +D + +L ++ EDAG ++ V KN+ G ++ +L
Sbjct: 2559 YLNGNPLSASSR-RILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTR 2617
Query: 602 -APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD------EGSDILLE 654
A L D E + EG P + K Q + EGS LLE
Sbjct: 2618 AAILGDTQHEQSWQRIQEIEAPRAPGAEPEG--PVYEKPSFVQPLQSVGDLPEGSVALLE 2675
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
RLV + +P+ + W + + ++ IS + + C L+I V G Y+ A
Sbjct: 2676 ARLVPVNDPNLRVQWFYNDQPLMESNWISTSND----FGCVSLRIAPVYARHTGVYSCKA 2731
Query: 713 VNREGEA 719
N G A
Sbjct: 2732 WNDSGNA 2738
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/184 (20%), Positives = 68/184 (36%), Gaps = 12/184 (6%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWER-DGEIIKPKKNKYDFEKRGH-IRK 1073
P+F+ Q K + ++ + T + W++ DG +I+ KY E +
Sbjct: 706 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQ-SGGKYKIENGPDGSGR 764
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAE------VTVVELP--PEIITRLQNQKVNKGNKAT 1125
L I HD Y + R++ + + V + P PE + Q+ + G+
Sbjct: 765 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVK 824
Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
+ +WFKD I + G + L I + + + G Y C+ N
Sbjct: 825 LYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRCDATNKHG 884
Query: 1186 TAIL 1189
T L
Sbjct: 885 TTTL 888
Score = 43.2 bits (97), Expect = 0.002
Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 18/223 (8%)
Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P FV++L P +G V E QV +T W + + F + D +A
Sbjct: 1728 PAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRFVLSQDFGYIA 1787
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMTVXXXXXXXXXX 623
L I +PED GT+T V +N AG A ST ++ +D ++
Sbjct: 1788 -LNILYCYPEDNGTYTLVVRNRAGEAQSTVDINCGHTGGNFTDSFHPNSLHRIAELETPI 1846
Query: 624 XXADIL---EGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVP 676
A+ L E PT +K A V E + LE ++ I + + WLF G +
Sbjct: 1847 QRAEPLPDKEKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKA 1906
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
V +D L I + G YT+V N G A
Sbjct: 1907 SSRYRVL--NDFGFVS--LDIDYIIAEDSGKYTLVVYNSAGRA 1945
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT--ITWCKNNKPV-KALPTKSDGDTH 787
E + PQ IEPL S+ + +S +V P I W K+ +P+ + K D
Sbjct: 2387 EHDAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFG 2446
Query: 788 SITILKPKKV-KDEGVYTLKAENSEGIAETSAVITV 822
I++ V +D GVY++KA N++G AE A +TV
Sbjct: 2447 YISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTV 2482
Score = 41.5 bits (93), Expect = 0.006
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 526 TVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
TV F +V G P P +TW + +I+ +++ D L+I +V DA + V
Sbjct: 722 TVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRLIIEKVDAHDADMYMLV 781
Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMT 612
A+N G S L V S E T
Sbjct: 782 ARNDGGSFQSRFSLNVLQAKSPEAPEFT 809
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 821 TVEEPTEENA-EPPLFINRFQ-EITVKEKGTIKLVARVT-RNPVP-SITWYRNNEIISPS 876
+VE P E N+ E P F +I V E + AR+ N V ++ WY N + +
Sbjct: 1315 SVERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAA 1374
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
FD + L + + DSG Y VA N G++ + + EKV +++
Sbjct: 1375 HRFHPMFDFGYVALDLLYAYPQ-DSGTYTLVARNELGEARSNVELVVGTEKVLYLE 1429
Score = 41.5 bits (93), Expect = 0.006
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 1285 EFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E P + +E + G VTL LV+ P EW++N ++ + + +
Sbjct: 2785 EKPQWVQGFENYENVGEGQTVTLHGLVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN 2844
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
A LTI V D+G+Y R N G A VT
Sbjct: 2845 AILTIVHVLPHDSGVYTCRAWNTQGEASTSATVT 2878
Score = 41.5 bits (93), Expect = 0.006
Identities = 53/264 (20%), Positives = 93/264 (35%), Gaps = 25/264 (9%)
Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
E+++ Q+ Q KL + + +E AP F +L+ +G +FE QV
Sbjct: 3935 ESHFKQHSQAKLQLTANDI------YNESDKRAPEFRTQLQNIGVLEGEFCRFETQVAPI 3988
Query: 537 PRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
P ++ WF+ + F+ D A L + P+D G + CVA N G
Sbjct: 3989 NDPYLKVEWFKDKKPVLLGHRFRSTLDF-GFACLDLLYALPDDTGEYHCVATNRHGQTMI 4047
Query: 595 TTELIVEAPL-----SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP------KAQ 643
+ +L + S + V ++ + P + P +
Sbjct: 4048 SAKLACQGASHVITDSQMPQGLRVSNVKKDNKNIYWSEQGGAVQPKQKQAPQFTIPLRNL 4107
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V E EC + P P + W G + + + + ++ S +I++
Sbjct: 4108 QVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDA--- 4164
Query: 704 QEGTYTVVAVNREGEASLPIVLKI 727
G +A N EGE L I
Sbjct: 4165 --GEVVAIARNTEGETISTATLDI 4186
Score = 40.7 bits (91), Expect = 0.011
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAG 1652
+PPP + W KNG L+N + I +KT +I I ++ + +YTI+A+N G
Sbjct: 162 VPPPNIEWMKNGKPLQNYRA-KIEHDQKTGIISLIIPQMFNDDAGEYTIKATNVHG 216
Score = 40.7 bits (91), Expect = 0.011
Identities = 44/207 (21%), Positives = 76/207 (36%), Gaps = 6/207 (2%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A ++ PP F P++ + ++V P P + W K + V IE
Sbjct: 698 AALVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSGGKYKIE 756
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSM 744
+ L I V Y +VA N G L + + E P+ +S
Sbjct: 757 NGPD-GSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQST 815
Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITI-LKPKKVKDEGV 802
+ G+SV L + G + W K+N+P+ + + + D + T+ + +K+ G
Sbjct: 816 TLYDGDSVKLYCKAAGE-GVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGW 874
Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN 829
Y A N G + V + N
Sbjct: 875 YRCDATNKHGTTTLKGRVVVNSRQKFN 901
Score = 40.7 bits (91), Expect = 0.011
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P + I R++ Q + K T + T + ++WFKDG + SN +LT D L I
Sbjct: 2396 PLDSIDRMEFQSAHFQTKVTPQ---TDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDI 2452
Query: 1166 YDCDLDDAGEYSCEVGNSK 1184
+D+G YS + N+K
Sbjct: 2453 AHTVPEDSGVYSVKASNAK 2471
Score = 40.3 bits (90), Expect = 0.015
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTK 1624
G+ KP+I ++ G + ++ A I G P P + W NG L+ + +T K
Sbjct: 298 GVGTKPIIRTPLRGLRLTE--GTDAILQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTYK 355
Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
+V++I + + YT+ + N G ++VY
Sbjct: 356 GSMAVLKISMVTTEEAGDYTVASENRFGKVESSARIEVY 394
Score = 40.3 bits (90), Expect = 0.015
Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 730 GEKEPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKS 782
G +EPP + PL++ + V +GE + L QV + + I W ++ + + T
Sbjct: 1590 GPQEPPTFVVPLQADLGDVEEGEPIHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFY 1649
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
D S+ IL +D G YT +AENS G AET A I
Sbjct: 1650 DFGFVSLDILG-FYAQDAGTYTCRAENSLGQAETVATI 1686
Score = 40.3 bits (90), Expect = 0.015
Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%)
Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVV--GNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
PP+ + L S+ V +G+ AQ + +P+ ++ W N P+ A + + +
Sbjct: 2521 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 2580
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVIT----------------------VEEPT 826
L + +D G Y++ +NSEG TS ++ +E P
Sbjct: 2581 SLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTRAAILGDTQHEQSWQRIQEIEAPR 2640
Query: 827 EENAEP-------PLFINRFQEITVKEKGTIKLV-ARV--TRNPVPSITWYRNNEIISPS 876
AEP P F+ Q + +G++ L+ AR+ +P + W+ N++ + S
Sbjct: 2641 APGAEPEGPVYEKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMES 2700
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I+ + D + L I V + +G Y C A N +G + A V +
Sbjct: 2701 NWISTSNDFGCVSLRIAPVYAR-HTGVYSCKAWNDSGNAVTSANVGV 2746
Score = 39.9 bits (89), Expect = 0.019
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATL 568
PI LR +G+ + + G P+P+I W F + QM Y ++A L
Sbjct: 303 PIIRTPLRGLRLTEGTDAILQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTY-KGSMAVL 361
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
I V E+AG +T ++N G S+ + V PLS
Sbjct: 362 KISMVTTEEAGDYTVASENRFGKVESSARIEV-YPLS 397
Score = 39.5 bits (88), Expect = 0.026
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
Q+P PL+N+ N+ C G P+PKVTW+ +G +
Sbjct: 4096 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQ 4137
Score = 39.5 bits (88), Expect = 0.026
Identities = 21/78 (26%), Positives = 36/78 (46%)
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
++G V + P+P +W K I + K S D K A L + +V AG Y+
Sbjct: 4810 RQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQ 4869
Query: 1360 LRLENNCGHADVEMNVTI 1377
+ + N+ G A + +T+
Sbjct: 4870 IVIRNDKGAATSQAKLTL 4887
Score = 39.1 bits (87), Expect = 0.034
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVEN 1352
R +K G+ VT A P PN EW+ N K ++ + K D K+ SL I ++ N
Sbjct: 143 RHQPLKPGAGVTFEGRVIAVPPPNIEWMKNGKPLQNYR-AKIEHDQKTGIISLIIPQMFN 201
Query: 1353 TDAGIYKLRLENNCGHA 1369
DAG Y ++ N G A
Sbjct: 202 DDAGEYTIKATNVHGEA 218
Score = 39.1 bits (87), Expect = 0.034
Identities = 58/279 (20%), Positives = 103/279 (36%), Gaps = 22/279 (7%)
Query: 490 EKIDKLPVFEKPT-SEEQSMAPIF-----VEKLRPKHTPDGSTVQFECQVEGY--PRPQI 541
E ++ + E P +E ++ AP++ ++ K +G V FE + PR Q+
Sbjct: 3025 ESWKRIQILEAPKEAEPEAPAPVYDHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQV 3084
Query: 542 TWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV- 600
W R + + + D + TL + +PED G + N G A S+ L
Sbjct: 3085 QWIRNGVPLAHGSKYAIQ-QDFGICTLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCH 3143
Query: 601 --EAPLSD---HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLE 654
+A L D S + AD PP F ++ + E E
Sbjct: 3144 GKDAILGDVQHQESWKRIQEIEAPKQKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFE 3203
Query: 655 CRLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
+ + +P I W GE + + + +D ++ I + G + VA
Sbjct: 3204 ATVEPVDDPTLTINWFLNGEPMSASSRVKMI--NDFGWV--IMDIAQTEPRDSGEWKCVA 3259
Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
N GEA ++++ E ++P +RQ E+
Sbjct: 3260 KNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEA 3298
Score = 38.7 bits (86), Expect = 0.045
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P I L +++ G E +L D ++W KDG + ++ DG K +L I
Sbjct: 18 PTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSMCPDYRIEEDGLKHRLVI 77
Query: 1166 YDCDLDDAGEYSCEVGNSKCT 1186
D+G ++ + NS T
Sbjct: 78 PQVQAADSGRFTAQASNSAGT 98
Score = 38.7 bits (86), Expect = 0.045
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 731 EKEPPQVIEPLKSMI--VRQGESVILSAQVVGNPRPTIT--WCKNNKPVKALPTKSDGDT 786
EKE P + +PL + I V + +++ L AQV T+ W N P+KA +
Sbjct: 1856 EKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKASSRYRVLND 1915
Query: 787 HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE 823
L + +D G YTL NS G AETS V+
Sbjct: 1916 FGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1954
Score = 38.7 bits (86), Expect = 0.045
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PE T+LQN V +G FE ++ D V WFKD + + + T+D L
Sbjct: 3962 PEFRTQLQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACL 4021
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
+ DD GEY C N
Sbjct: 4022 DLLYALPDDTGEYHCVATN 4040
Score = 38.3 bits (85), Expect = 0.059
Identities = 74/395 (18%), Positives = 151/395 (38%), Gaps = 25/395 (6%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P FIR L D + ILE ++ + W +DG + + Y E+ G +L
Sbjct: 18 PTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSMCPD-YRIEEDGLKHRLV 76
Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
I D G ++ + + T + T + + T + K + A + + G +
Sbjct: 77 IPQVQAADSGRFTAQASNSAGTKQSTCILICAPAPTPVPGAKSAVASPAPPQTPV--GPS 134
Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE----YSCEVGNSKCTAILTV 1191
+ K+ +T +G+ + + + G+ Y ++ + + T I+++
Sbjct: 135 APIFLKELRHQPLKPGAGVTFEGRVIAVPPPNIEWMKNGKPLQNYRAKIEHDQKTGIISL 194
Query: 1192 EEPSINFTLRLPEFILVPANT--DAYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDV 1248
P + F E+ + N +A ++ P E D + +++ + K L+S
Sbjct: 195 IIPQM-FNDDAGEYTIKATNVHGEAISGAQLLPREQYDRWFSNEQTRLTKDRKQGLLSQT 253
Query: 1249 KKRTLIIRKCTED-----DQCEYTCVLLDAKSTTKLKVEVVEF-----PPKIVDYEREYR 1298
+ + + +K + DQ ++S T+ ++ ++ P I R R
Sbjct: 254 LRPSSVAQKQMQKQGYDTDQGSVDMHWTISESETEPELSALDARGVGTKPIIRTPLRGLR 313
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGI 1357
+ G+D L + P+P +W+ N + ++ + + A L I V +AG
Sbjct: 314 LTEGTDAILQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTYKGSMAVLKISMVTTEEAGD 373
Query: 1358 YKLRLENNCGHADVEMNVTI--LDKPSPPGKPNIL 1390
Y + EN G + + + L P K N L
Sbjct: 374 YTVASENRFGKVESSARIEVYPLSVPDERRKENQL 408
Score = 37.9 bits (84), Expect = 0.078
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888
N P FI + TI L ++ +P P+I W ++ +S DG
Sbjct: 14 NRVAPTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSMCPDYRIEEDGLKH 73
Query: 889 ELVITNVDSEIDSGDYKCVASNSAG 913
LVI V + DSG + ASNSAG
Sbjct: 74 RLVIPQVQA-ADSGRFTAQASNSAG 97
Score = 37.9 bits (84), Expect = 0.078
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
+P + W N I S I+ + L+I ++ + D+G+YKCVA+N G ++
Sbjct: 3749 DPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAA-DAGEYKCVATNVKGSATSV 3807
Query: 919 ARVTID----VEKVTFVKHLQKSYET-EEGKTVILECQTS 953
++ ++ ++ V+ L S E EG ++ LEC+ +
Sbjct: 3808 GKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVT 3847
Score = 37.5 bits (83), Expect = 0.10
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNN 772
E EA P + PP+ L +++G+ L QV V +PR I W N
Sbjct: 3565 EIEAPRPAREDAPDADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNG 3624
Query: 773 KPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+PV K+ D + + L P + +D G +T +A N G E S + V
Sbjct: 3625 QPVNHTNRMKAIHDFGFVVLQLTPAEPQDSGTWTCRATNQHGSDEVSTELKV 3676
Score = 37.1 bits (82), Expect = 0.14
Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 1107 PEIITRLQNQ-KVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
P I+ LQ Q + +G A + + T V W KDG I SN ++ D
Sbjct: 3314 PAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHSNRYKMVHDFGFAV 3373
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIP 1221
L I DAGEY+ V N+ A S +F + IL P N VEI
Sbjct: 3374 LDILHLLKHDAGEYTFRVSNNSGEA-----STSTSFEVSESSGLILQPQNEQKAKAVEIL 3428
Query: 1222 DETL 1225
++ L
Sbjct: 3429 EDNL 3432
Score = 36.7 bits (81), Expect = 0.18
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 36/249 (14%)
Query: 709 TVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPT 765
T+ V++ + P+ L+ + K P+ L+S + +G+S L + V +P
Sbjct: 910 TLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLR 969
Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
I W N K + A + T +D ++ I P V D+G YT+ A N G A SA I V
Sbjct: 970 IAWLLNGKGILASSRIVTFTDFGIAALEI-NPVNVFDQGEYTVVAVNPLGEARVSANIAV 1028
Query: 823 --------------------------EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
+ P + + P F + + V E I L ++
Sbjct: 1029 IGHGSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKL 1088
Query: 857 T--RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
T +P + W + + ++ Q L I S DSG Y C A N G+
Sbjct: 1089 TPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSN-DSGLYSCRAFNKLGE 1147
Query: 915 SSHGARVTI 923
S + A + I
Sbjct: 1148 SENQATIII 1156
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQ-NFDGENIELVITNVDSEIDSGDYKCVASN 910
L A + NP P I W N + S Q + G L I+ V +E ++GDY + N
Sbjct: 322 LQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTYKGSMAVLKISMVTTE-EAGDYTVASEN 380
Query: 911 SAGKSSHGARVTI 923
GK AR+ +
Sbjct: 381 RFGKVESSARIEV 393
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P + L++Q+V +G + E +LT D V W DG+E+ ++ + T+ L
Sbjct: 1065 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 1124
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
I +D+G YSC N
Sbjct: 1125 DIPQTSSNDSGLYSCRAFN 1143
Score = 36.3 bits (80), Expect = 0.24
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDGD 785
+PP E L ++G+S+ L ++ V +P +TW +N +P+ + +P ++ D
Sbjct: 2124 QPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPLPEASRFMPARNF-D 2182
Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++ IL +D GVYT KA ++ G A TS +
Sbjct: 2183 YVNLDILALYG-EDSGVYTCKAVSAFGEAATSCTV 2216
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P + W+K+G L N + +TT + I S Y+++ASN G + V+
Sbjct: 2420 PNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQ 2479
Query: 1660 LKV 1662
L V
Sbjct: 2480 LTV 2482
Score = 36.3 bits (80), Expect = 0.24
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
+P ++ A P F + + V E + VT P P +TW+ N NF
Sbjct: 4091 QPKQKQA--PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNF 4148
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
DG + + + D+G+ +A N+ G++ A + I
Sbjct: 4149 DG--LHYLTVSKSRISDAGEVVAIARNTEGETISTATLDI 4186
Score = 35.9 bits (79), Expect = 0.32
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870
+ E E+P E+ + P FI I E + +VT P+ I W+++
Sbjct: 2372 VLEAPRAAAPEKPDAEH-DAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDG 2430
Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ + S D I L I + E DSG Y ASN+ G + A++T+
Sbjct: 2431 QPLMNSNRFKLTTDFGYISLDIAHTVPE-DSGVYSVKASNAKGDAEVQAQLTV 2482
Score = 34.7 bits (76), Expect = 0.73
Identities = 17/66 (25%), Positives = 31/66 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P V+W +GN+L ++ +Y T + + I + + S Y+ A N G S + T
Sbjct: 1094 PDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSNDSGLYSCRAFNKLGESENQAT 1153
Query: 1660 LKVYDK 1665
+ + K
Sbjct: 1154 IIIVPK 1159
Score = 34.3 bits (75), Expect = 0.97
Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
+P F L+ EV E LE + IN VVW DG + P +KY
Sbjct: 1064 LPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFA 1122
Query: 1073 KLYIRNTSVHDEGEYSC 1089
L I TS +D G YSC
Sbjct: 1123 SLDIPQTSSNDSGLYSC 1139
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 1013 KETIPEFIRKLQDFEVKEK-DVAILEVEI---NSETADVVWERDGEIIKPKKNKYDFEKR 1068
++ P+F+ ++Q F +++ + E I N T V W +DG+ + P N+ +
Sbjct: 1186 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNANRIQIFQN 1244
Query: 1069 GHIRKLYIRNTSVHDEGEYSCIL 1091
+ L + T D G Y+C+L
Sbjct: 1245 FGVVSLSLHPTYPEDAGVYTCVL 1267
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P +V W K+G + + Y + +V+ I L + + +YT SN +G +S +
Sbjct: 3344 PSIKVEWLKDGQPIFHSNRYKMVHDFGFAVLDILHLLKHDAGEYTFRVSNNSGEASTSTS 3403
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIE 1686
+V S+ G ++ + +++ +E
Sbjct: 3404 FEV----SESSGLILQPQNEQKAKAVE 3426
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASL 1345
PK + ++ G L + Y PN W++N K I D A+L
Sbjct: 937 PKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILASSRIVTFTDFGIAAL 996
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
I V D G Y + N G A V N+ ++
Sbjct: 997 EINPVNVFDQGEYTVVAVNPLGEARVSANIAVI 1029
Score = 33.1 bits (72), Expect = 2.2
Identities = 47/216 (21%), Positives = 81/216 (37%), Gaps = 12/216 (5%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P F LR + +G + E ++ P ++ W + PS D A+
Sbjct: 1065 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFAS 1123
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXA 626
L I + D+G ++C A N G + + +I+ P SD E A
Sbjct: 1124 LDIPQTSSNDSGLYSCRAFNKLGESENQATIII-VPKSDLQQFEQHRQLDVEDVREIQFA 1182
Query: 627 DILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVA 683
+ + P F + + + + E E R+ I +P ++WL G+ + P+ N
Sbjct: 1183 HSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNAN---R 1238
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I+ + L + G YT V N G+A
Sbjct: 1239 IQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 1274
Score = 33.1 bits (72), Expect = 2.2
Identities = 16/47 (34%), Positives = 25/47 (53%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
V W KDG + +N IQ+ + L ++ +DAG Y+C + NS
Sbjct: 1224 VSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNS 1270
Score = 33.1 bits (72), Expect = 2.2
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 1106 PPEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
PP+ +T+L + V +G + FE I + V+W+ +G+ + S+ L D
Sbjct: 2521 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 2580
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK 1184
L + +DAGEYS V NS+
Sbjct: 2581 SLDLQYTLGEDAGEYSVVVKNSE 2603
Score = 32.7 bits (71), Expect = 3.0
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 7/116 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKN 771
R+ EA P + + E P ++ L+ + +G S L Q V +P + W K+
Sbjct: 3294 RQIEAGKPAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKD 3353
Query: 772 NKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
+P+ D + IL K D G YT + N+ G A TS V E
Sbjct: 3354 GQPIFHSNRYKMVHDFGFAVLDILHLLK-HDAGEYTFRVSNNSGEASTSTSFEVSE 3408
Score = 32.3 bits (70), Expect = 3.9
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 735 PQVIEPLKSMIVRQGES--VILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITI 791
P+ + L + + + E+ V L A V +P I W N +P+ K+ + I +
Sbjct: 1462 PKFLNDLPDIQLNEHENIHVDLRATPVNDPTMVIEWFVNGRPLLTGSRVKTLNEFGFIAL 1521
Query: 792 -LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+K +D G Y+++A N G A VITV
Sbjct: 1522 DIKGAIAEDSGTYSVRASNLLGEAIRQCVITV 1553
Score = 32.3 bits (70), Expect = 3.9
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTIT--WCKN 771
+E EA P ++ +PP ++ L I +G++V L AQV ++T W N
Sbjct: 1708 QEIEAPKPAPQEVPDLPHQPPAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVN 1767
Query: 772 NKPV-KA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
+P+ KA D ++ IL +D G YTL N G A+++ I
Sbjct: 1768 GQPLMKAHRFVLSQDFGYIALNILYCYP-EDNGTYTLVVRNRAGEAQSTVDI 1818
Score = 31.9 bits (69), Expect = 5.2
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIA 814
Q + +P ++W K+ +P+ + L P +D GVYT NS G A
Sbjct: 1215 QPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 1274
Query: 815 ETSAVIT 821
++SA +T
Sbjct: 1275 QSSAELT 1281
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
+A ++G P P V W G + I+ K +++ + + + +Y I N G
Sbjct: 4818 SAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQIVIRNDKG 4877
Query: 1653 --TSSVEVTL 1660
TS ++TL
Sbjct: 4878 AATSQAKLTL 4887
Score = 31.5 bits (68), Expect = 6.8
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+PT +PL + E I L C G P P + W +DG
Sbjct: 17 APTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDG 55
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/66 (24%), Positives = 29/66 (43%)
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
Q P +W + + + K + D SL I D+G+Y ++ N G A+V
Sbjct: 2417 QTDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEV 2476
Query: 1372 EMNVTI 1377
+ +T+
Sbjct: 2477 QAQLTV 2482
Score = 31.1 bits (67), Expect = 9.0
Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ G P P+V W+ NGN+ + + + + + + + + S + + A NT G +
Sbjct: 4121 VTGYPRPKVTWFINGNQCLHGHRFKLNF-DGLHYLTVSKSRISDAGEVVAIARNTEGETI 4179
Query: 1656 VEVTLKVY 1663
TL ++
Sbjct: 4180 STATLDIF 4187
>AB026846-1|BAA90302.2| 4219|Caenorhabditis elegans kettin protein.
Length = 4219
Score = 113 bits (271), Expect = 2e-24
Identities = 113/458 (24%), Positives = 188/458 (41%), Gaps = 64/458 (13%)
Query: 500 KPTSEEQSMA--PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
+PT QS P ++L+P G +F + G ++TW + IK +
Sbjct: 3790 QPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTL 3849
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ N ++L I + AG +T +NAAG S L V P +
Sbjct: 3850 ITTTPTN-SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTT------------ 3896
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
+G P FS + + + C++ P+P I W G+ + D
Sbjct: 3897 ------------QGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPND 3944
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---KTGEK-- 732
+ V E + LK +N+ G Y +VA N GEA L + KTG+
Sbjct: 3945 DRFQVVEEGGAYK----LKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAE 4000
Query: 733 -----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
E P+ ++ ++V +G+ SAQ G P PTI W +NN+PVK +
Sbjct: 4001 EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSK 4060
Query: 788 SITILKPKKVKDEGV--YTLKAENSEGIAETSA--VIT------------------VEEP 825
IL+ ++E V Y ++A N G A + A V+T +
Sbjct: 4061 GEAILRISAARNEDVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSS 4120
Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
+ A+ P FI + +I+ ++ T+K A V NP P++ W + IS S + + DG
Sbjct: 4121 DKAAADSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDG 4180
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ L + V + +G+Y+ V N G ++ A++T+
Sbjct: 4181 KRAILELARVTPD-SAGEYQIVIRNDKGAATSQAKLTL 4217
Score = 84.2 bits (199), Expect = 9e-16
Identities = 64/272 (23%), Positives = 121/272 (44%), Gaps = 18/272 (6%)
Query: 722 PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
P KI ++ PP + + LK + G++ + G +TW K+ K +K+
Sbjct: 3789 PQPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRT 3848
Query: 782 SDGDTHSITILKPKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
T + + L ++++ G YT++ EN+ G E+ A +TV PT + P F R
Sbjct: 3849 LITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPD-FSARL 3907
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ +++ G + ++ P P+I W+++ + + + +G +L +N+ S
Sbjct: 3908 NDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIIS-T 3966
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE------------TEEGKTVI 947
D+G Y+ VA N G++ AR+ ++++K YE +EGK
Sbjct: 3967 DAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQ 4026
Query: 948 LECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977
Q S + +WY N + + D EI Q
Sbjct: 4027 FSAQFSGFPDPTIRWYRNNEPVKHADGYEISQ 4058
Score = 72.5 bits (170), Expect = 3e-12
Identities = 83/350 (23%), Positives = 137/350 (39%), Gaps = 24/350 (6%)
Query: 491 KIDKLPVFEKPTSEEQSMA-----PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITW 543
K+DK+ P ++ Q ++ P F L+ + +G + + E + P +I W
Sbjct: 215 KVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAW 274
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
I S + + D +A L I V D G +T VA N G A + + V
Sbjct: 275 LLNGKGILASSRI-VTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGEARVSANIAVIGH 333
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIP---PTFSKKPKAQYVDEGSDILLECRLVAI 660
S + + A G P F ++Q V EG I LE +L I
Sbjct: 334 GSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKLTPI 393
Query: 661 PEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+PD + WL G E+ ++ + H + S L I G Y+ A N+ GE
Sbjct: 394 NDPDLRVVWLLDGNELPSNDKYRQTLS---HGFAS-LDIPQTSSNDSGLYSCRAFNKLGE 449
Query: 719 A--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ--GESVI-LSAQVVGNPRPTITWCKNNK 773
+ I++ + + P+ + ++ Q G S Q + +P ++W K+ +
Sbjct: 450 SENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQ 509
Query: 774 PVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIAETSAVIT 821
P+ + L P +D GVYT NS G A++SA +T
Sbjct: 510 PLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQAQSSAELT 559
Score = 66.1 bits (154), Expect = 3e-10
Identities = 119/539 (22%), Positives = 206/539 (38%), Gaps = 81/539 (15%)
Query: 474 LMDENNYTQYLQKKLN-EKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFEC 531
L+ + ++ LQK E IDK + P E + P +V+ ++ +G TV
Sbjct: 2046 LLLDTSHPASLQKIQELEAIDKYARLDAPEREYEK--PQWVQGFENYENVGEGQTVTLHG 2103
Query: 532 QVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
VE G P ++ W ++ + F+ Y+ N A L I V P D+G +TC A N
Sbjct: 2104 LVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN-AILTIVHVLPHDSGVYTCRAWNTQ 2162
Query: 590 GFASSTTELIV---EAPLSDHGSEMT---VXXXXXXXXXXXXADILEGIPPTF-SKKPKA 642
G AS++ + E L D ++ + +I++ P F ++ A
Sbjct: 2163 GEASTSATVTTAGYEKILYDSQHPVSWERIQELEAPKIVEEIEEIVQKEKPNFLTQLESA 2222
Query: 643 QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDE-----------NISVAIESDMH 689
+ V EG + LE +P+ + W G+ + + + ++ ++ H
Sbjct: 2223 ENVPEGVPLHLESTFQPARDPELKVVWQKNGQPLGASQLVQTKHELGWATLDISSANEDH 2282
Query: 690 MYCSVLKITNVKKFQ--------EGTYTVVAVNREGEASLPIVLKIKTGEKEP------- 734
L ITN + GT ++ R E+ I + E EP
Sbjct: 2283 NGVYTLTITNSEGEAVSTASIRVAGTGPILGNTRHEESWKRIQILEAPKEAEPEAPAPVY 2342
Query: 735 --PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
P + + +G+ V A + V +PR + W +N P+ + I
Sbjct: 2343 DHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQVQWIRNGVPLAHGSKYAIQQDFGIC 2402
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVI----------------------TVEEPT 826
L +DEGVY L+ N EG A +SA + +E P
Sbjct: 2403 TLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCHGKDAILGDVQHQESWKRIQEIEAPK 2462
Query: 827 EENAE-------PPLFINRFQ---EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
++ E PP FI + + + + +P +I W+ N E +S S
Sbjct: 2463 QKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSAS 2522
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
+ D + + I + DSG++KCVA N+AG++ A + + ++V LQ
Sbjct: 2523 SRVKMINDFGWVIMDIAQTEPR-DSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQ 2580
Score = 64.1 bits (149), Expect = 1e-09
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 23/248 (9%)
Query: 500 KPTSEEQS-MAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQ 554
KP+ ++ + P+F ++L P +G +V +C V+ P +I WF +
Sbjct: 1276 KPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGS 1335
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDH- 607
+ +D V L + PED GT+TC A N G +TT++ +E L H
Sbjct: 1336 RIRTIHDFGYVG-LEFLHIHPEDTGTYTCKATNLIG--EATTDIFLECKPRRNIYLDTHH 1392
Query: 608 -GSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD- 664
S + L PPTF++ + EG I LECRL+ + +P
Sbjct: 1393 ESSWQKIQEIENRVDEREPTPELTFQPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTM 1452
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+ W G+ + A D Y + L I + G YT AV+ GEA+
Sbjct: 1453 RVTWTRNGQPLPEASRFMPARNFD---YVN-LDILALYGEDSGVYTCKAVSAFGEAATSC 1508
Query: 724 VLKIKTGE 731
+K G+
Sbjct: 1509 TVKCAAGK 1516
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/319 (22%), Positives = 119/319 (37%), Gaps = 27/319 (8%)
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
+ PP I +L+ + G A F IE + V W KDG EI+ + +T
Sbjct: 3799 QAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSS 3858
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCT----AILTVEEPSI-----NFTLRLPEFILVPANTD 1213
L I + AGEY+ + N+ T A LTV P+ +F+ RL + + + N
Sbjct: 3859 LHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLND-LRIQQNGP 3917
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271
A + +I E + W+K + + ++F ++ + L D Y V
Sbjct: 3918 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 3977
Query: 1272 ---DAKSTTKLKVEVV-------EFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+A+ +L V + E P P+ + + G + FP P
Sbjct: 3978 GVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDP 4037
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W N++ +K + S A L I N D YK+ N G A N+ +
Sbjct: 4038 TIRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVL 4097
Query: 1378 LDKPSPPGKPNILEIDSSS 1396
+ K I S+S
Sbjct: 4098 TPRSGRIAKSTISRGGSAS 4116
Score = 62.1 bits (144), Expect = 4e-09
Identities = 83/338 (24%), Positives = 135/338 (39%), Gaps = 32/338 (9%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
P F L P +G ECQV PR I WF + + + +D V
Sbjct: 2878 PKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIHDFGFVV 2937
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---------PLSDHGSEMT-VXXX 616
L + P+D+GT+TC A N G +TEL V ++ +T +
Sbjct: 2938 -LQLTPAEPQDSGTWTCRATNQHGSDEVSTELKVVGGGGVSYEWQSTAERKERITELEDW 2996
Query: 617 XXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
++ P+FS+ ++E C L I +P + W G
Sbjct: 2997 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHP 3056
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK- 732
I IS E + + L I ++ G Y VA N +G A+ + +++ +
Sbjct: 3057 IPYSNRISCTNEFGV----ATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQI 3112
Query: 733 EPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDG 784
+ PQV++ L + + +G+S+ L +V + +PR + W +N P+ + PT G
Sbjct: 3113 DAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFG 3172
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S+ IL +D G Y L N +G A + ITV
Sbjct: 3173 FV-SLDILYAYP-EDNGDYELVVRNDKGEARSKTKITV 3208
Score = 59.3 bits (137), Expect = 3e-08
Identities = 43/197 (21%), Positives = 80/197 (40%), Gaps = 20/197 (10%)
Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRX 1533
T+ ++P L ++ + N E +C GG P+P + W++DG+ L + E
Sbjct: 3896 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 3955
Query: 1534 XXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVGIQ--------------QKPVITISNE 1578
Y+ +A N GE + + + P T +
Sbjct: 3956 YKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQ 4015
Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
I G ++ +A G P P + WY+N +++ Y I+ + +++RI +
Sbjct: 4016 PIVVDEGKGAQF--SAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4073
Query: 1639 HSSKYTIEASNTAGTSS 1655
++Y +EASN AG +S
Sbjct: 4074 DVAEYKVEASNPAGKAS 4090
Score = 54.8 bits (126), Expect = 6e-07
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+Q AP F LR + +FEC V GYPRP++TWF F++ +D +
Sbjct: 3387 KQKQAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLH 3446
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
T+ + DAG +A+N G ST L
Sbjct: 3447 YLTVSKSRI--SDAGEVVAIARNTEGETISTATL 3478
Score = 53.6 bits (123), Expect = 1e-06
Identities = 49/212 (23%), Positives = 82/212 (38%), Gaps = 15/212 (7%)
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKATY 1529
I ++K PT+ + LK + E + + F G KVTW +DGK++K T T
Sbjct: 3794 IGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTT 3853
Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQK 1583
Y N G VE+ + + + P + D++ +
Sbjct: 3854 PTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQ 3913
Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
E+ + I G P P + W+K+G L ND + + + ++ + + + Y
Sbjct: 3914 QNGPAEF--SCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIY 3971
Query: 1644 TIEASNTAGTSSVEVTLKV-YDKPSK--PEGP 1672
I A N G + + L V K K EGP
Sbjct: 3972 EIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4003
Score = 53.2 bits (122), Expect = 2e-06
Identities = 56/223 (25%), Positives = 85/223 (38%), Gaps = 17/223 (7%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P F+++L P + FE VE P +T WF + S +M +D
Sbjct: 2476 PRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMI-NDFGWV 2534
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTT-------ELIVEAPLSDHGSEMTVXXXXXX 619
+ I + P D+G + CVAKNAAG A ST E+I++ L +
Sbjct: 2535 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEAGK 2594
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVPD 677
D P + ++EG L+ + + +P I WL G+ I
Sbjct: 2595 PAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHS 2654
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
+ + +VL I ++ K G YT N GEAS
Sbjct: 2655 NRYKMVHDFGF----AVLDILHLLKHDAGEYTFRVSNNSGEAS 2693
Score = 51.6 bits (118), Expect = 6e-06
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 1191 VEEPSINFTLRLPEF-ILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISD 1247
V+ P+ +F+ L + L A+ A++ V P D TL V W I + + + ++
Sbjct: 3009 VDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNE 3068
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP-----PKIVDY--EREYRI 1299
TL+I+ D EY CV + K S T + VE P++V + I
Sbjct: 3069 FGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENI 3128
Query: 1300 KRGSDVTLLVDYQAFPQP--NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
G + L P + EW+ N + + KP+ + SL I D G
Sbjct: 3129 LEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFVSLDILYAYPEDNGD 3188
Query: 1358 YKLRLENNCGHADVEMNVTILDKPS 1382
Y+L + N+ G A + +T+L +PS
Sbjct: 3189 YELVVRNDKGEARSKTKITVLPRPS 3213
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/184 (27%), Positives = 82/184 (44%), Gaps = 17/184 (9%)
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
+P F L+ EV E LE + IN VVW DG + P +KY
Sbjct: 366 LPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFA 424
Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAE--VTVV-------ELPPEIITRLQNQKVNKG-N 1122
L I TS +D G YSC ++ +E T++ +L P+ ++++Q +
Sbjct: 425 SLDIPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELG 484
Query: 1123 KATFEIELTK-GDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
++ FE + D +R W KDG + +N IQ+ + L ++ +DAG Y+C
Sbjct: 485 RSFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCV 544
Query: 1180 VGNS 1183
+ NS
Sbjct: 545 LFNS 548
Score = 50.8 bits (116), Expect = 1e-05
Identities = 62/258 (24%), Positives = 101/258 (39%), Gaps = 23/258 (8%)
Query: 479 NYTQYLQKKLNEK-IDKLPVFEKPTSEEQS-MAPIFVEKL---RPKHTPDGSTVQFECQV 533
N +Y + ++ +K + P F P + ++P F K R +G + ECQV
Sbjct: 855 NLNKYGRVEIEDKGPQEPPTFVVPLQADLGDVSPTFFLKNTTNRYLQVEEGEPIHLECQV 914
Query: 534 EGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
+I W R + F+ +YD V+ L I + +DAGT+TC A+N+ G
Sbjct: 915 NPINDNSLKIIWLRDGQSLPHGHRFRTFYDFGFVS-LDILGFYAQDAGTYTCRAENSLGQ 973
Query: 592 ASSTTEL------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK--PKAQ 643
A + + + + S + L PP F K+ P Q
Sbjct: 974 AETVATIRCAPKDAILGAVQHPRSYARIQEIEAPKPAPQEVPDLPHQPPAFVKQLGPAIQ 1033
Query: 644 YVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
+ EG ++ LE ++ + + WL G+ ++ + D L I
Sbjct: 1034 CM-EGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRF--VLSQDFGYI--ALNILYCY 1088
Query: 702 KFQEGTYTVVAVNREGEA 719
GTYT+V NR GEA
Sbjct: 1089 PEDNGTYTLVVRNRAGEA 1106
Score = 50.8 bits (116), Expect = 1e-05
Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 23/273 (8%)
Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR-PKHTPDGSTVQFECQ 532
L +N + L + + + P E+ E + P+F+E L P T +G F +
Sbjct: 2708 LQPQNEQKAKAVEILEDNLRRRP--EEIEQELKEATPVFIEPLSAPVETEEGGRAHFTAR 2765
Query: 533 VEGYP--RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
E + Q+ W+ +K + + L I +PED G + C A N G
Sbjct: 2766 YEPVNDNQLQVQWYHDGRPLKNGSRIKTI-NSFGYVVLEISPTYPEDNGEYICRAVNRVG 2824
Query: 591 FASSTTEL-------IVEA---PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKK 639
A ++T+L I+ A P + + A + PP F S
Sbjct: 2825 EAVTSTKLTCTPKEGIISATQLPERMANAGRRIAEIEAPRPAREDAPDADHGPPKFTSAL 2884
Query: 640 PKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
+ EG LEC++ + +P I W G+ + N + +++ VL++
Sbjct: 2885 AGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPV----NHTNRMKAIHDFGFVVLQL 2940
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730
T + GT+T A N+ G + LK+ G
Sbjct: 2941 TPAEPQDSGTWTCRATNQHGSDEVSTELKVVGG 2973
Score = 50.4 bits (115), Expect = 1e-05
Identities = 63/272 (23%), Positives = 109/272 (40%), Gaps = 31/272 (11%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDG 885
NA PP F+ Q + K T+ A+V P PS+TW +++ + S I DG
Sbjct: 64 NARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDG 123
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
L+I VD+ D+ Y VA N G + ++D + H+ + +EG
Sbjct: 124 SG-RLIIEKVDAH-DADMYMLVARNDGG----SFQSSVDNKGNETTLHINNA-TMKEGGW 176
Query: 946 VILECQTSHTVST----KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
+ H +T +++++ +G HRE+I + +
Sbjct: 177 YRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREMITLRKVDKVERSRTPVNQL------- 229
Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKP 1058
Q+ S ++ P+F LQ ++ E A LE++ + + W +G+ I
Sbjct: 230 --QDVS----ASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILA 283
Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
F G I L I +V D+GEY+ +
Sbjct: 284 SSRIVTFTDFG-IAALEINPVNVFDQGEYTVV 314
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816
+G+P + W N P+ S + + L K + D G Y A N +G A +
Sbjct: 3041 IGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATS 3100
Query: 817 SAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVT--RNPVPSITWYRNNEII 873
I VE T+ +A P + + + E +I L RVT +P + W RN +
Sbjct: 3101 VGKIAVESSTQIDA-PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPL 3159
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ F+ + L I E D+GDY+ V N G++ ++T+
Sbjct: 3160 PEASRFKPTFEFGFVSLDILYAYPE-DNGDYELVVRNDKGEARSKTKITV 3208
Score = 49.6 bits (113), Expect = 2e-05
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 16/176 (9%)
Query: 556 FQMYYDDD-NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS---EM 611
FQ D+ N TL I ++ G + C A N G + ++V + +G EM
Sbjct: 151 FQSSVDNKGNETTLHINNATMKEGGWYRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREM 210
Query: 612 -TVXXXXXXXXXXXXADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPD- 664
T+ + L+ + P F ++Q + EG LE + + +P+
Sbjct: 211 ITLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNL 270
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
IAWL G+ I+ I + + + L+I V F +G YTVVAVN GEA
Sbjct: 271 RIAWLLNGKGILASSRIVTFTDFGI----AALEINPVNVFDQGEYTVVAVNPLGEA 322
Score = 48.4 bits (110), Expect = 6e-05
Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 20/243 (8%)
Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
E+P AP F +L K + V FE ++ + + W+ + +
Sbjct: 595 ERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAAHR 654
Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP----LSDHGSE- 610
F +D VA L + +P+D+GT+T VA+N G A S EL+V L H E
Sbjct: 655 FHPMFDFGYVA-LDLLYAYPQDSGTYTLVARNELGEARSNVELVVGTEKVLYLEPHHPEG 713
Query: 611 MTVXXXXXXXXXXXXADI----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD-- 664
+ A++ + P + P Q ++E +I ++ R + +P
Sbjct: 714 LERIKELEQDRRQGIAEVEDRTCDAAPKFLNDLPDIQ-LNEHENIHVDLRATPVNDPTMV 772
Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
I W G ++ + E L I GTY+V A N GEA V
Sbjct: 773 IEWFVNGRPLLTGSRVKTLNEFGF----IALDIKGAIAEDSGTYSVRASNLLGEAIRQCV 828
Query: 725 LKI 727
+ +
Sbjct: 829 ITV 831
Score = 48.4 bits (110), Expect = 6e-05
Identities = 52/257 (20%), Positives = 98/257 (38%), Gaps = 10/257 (3%)
Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
E+D VK T T ++L+ + + +I E + ++ + +Q
Sbjct: 3650 ELDVPARDQVKLKTAKPTRGKDLEAGEKVKLKTEKAKIKEIQQKPEQPKEEPIVHKDAVQ 3709
Query: 1481 SPTVEKPLKNI-----TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535
T + P I T + +D++ T V +P + R K+ + T ++
Sbjct: 3710 LKTQQLPKTGIKGDHFTVDREKDLKET---PAVVKPVIEETRISNKVYLSVETADSFSQV 3766
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
+ I F+ T +G ++ TIS + + ++G
Sbjct: 3767 QRLEYSPRSPRRERIIGFHMIRPQPTK--IGQSKQAPPTISQQLKPLQGELGKAAKFVIE 3824
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
G P +V W K+G ++++ ITT S + I L+ SH+ +YT+ N AGT
Sbjct: 3825 FAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVE 3884
Query: 1656 VEVTLKVYDKPSKPEGP 1672
L V ++ + P
Sbjct: 3885 SLANLTVAPPTTQGKAP 3901
Score = 48.4 bits (110), Expect = 6e-05
Identities = 52/257 (20%), Positives = 97/257 (37%), Gaps = 24/257 (9%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PP I + + + G ++++ W+ + K IK T + ++SL
Sbjct: 3801 PPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLH 3860
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
I ++EN+ AG Y +RLEN G + N+T+ P+ GK + + I + P
Sbjct: 3861 IGRLENSHAGEYTVRLENAAGTVESLANLTVA-PPTTQGKAPDFSARLNDLRIQQNGPAE 3919
Query: 1407 TG------NSTIIYYVVEYQEIDTTEWISV-----------KNITKTQTSIQNL-KTNSS 1448
I + + Q + + V NI T I + N
Sbjct: 3920 FSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGV 3979
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
R A V++ + E + + ++P ++ I + + + + F G
Sbjct: 3980 GEARCKARLNVNLQKTGKGAE-----EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGF 4034
Query: 1509 PQPKVTWYRDGKKLKTA 1525
P P + WYR+ + +K A
Sbjct: 4035 PDPTIRWYRNNEPVKHA 4051
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDG-STV 527
+P D Y+ KL E ++ + S Q + P F+ +++P H
Sbjct: 428 IPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSS-QDLTPKFLSQIQPFHCEQELGRS 486
Query: 528 QFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
FE +++ P +++W + + + Q++ + V +L + +PEDAG +TCV
Sbjct: 487 FFEARIQPINDPTLRVSWLKDGQPLPNANRIQIF-QNFGVVSLSLHPTYPEDAGVYTCVL 545
Query: 586 KNAAGFASSTTEL 598
N+ G A S+ EL
Sbjct: 546 FNSHGQAQSSAEL 558
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 13/197 (6%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
P L+S V +G+ + L ++ + +P + W + + + +H L
Sbjct: 367 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 426
Query: 793 KPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK-GT 849
+ D G+Y+ +A N G +E A I + + ++ P F+++ Q +++ G
Sbjct: 427 DIPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPK-FLSQIQPFHCEQELGR 485
Query: 850 IKLVARVT--RNPVPSITWYRNNEIISPSETIT--QNFDGENIELVITNVDSEIDSGDYK 905
AR+ +P ++W ++ + + + I QNF ++ L T + D+G Y
Sbjct: 486 SFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPE---DAGVYT 542
Query: 906 CVASNSAGKSSHGARVT 922
CV NS G++ A +T
Sbjct: 543 CVLFNSHGQAQSSAELT 559
Score = 46.0 bits (104), Expect = 3e-04
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 11/157 (7%)
Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQVV--GNPRPTITWCKNNKPVKA---LPTKSDGDT 786
E P ++PL+S+ + +G +L A++V +P + W N++P+ + T +D
Sbjct: 1946 EKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMESNWISTSNDFGC 2005
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITV 844
S+ I P + GVY+ KA N G A TSA + V+ E + P + + QE+
Sbjct: 2006 VSLRIA-PVYARHTGVYSCKAWNDSGNAVTSANVGVQGSEGLLLDTSHPASLQKIQELEA 2064
Query: 845 KEKGTIKLVARVTRNPVPS-ITWYRNNEIISPSETIT 880
+K +L A P + + N E + +T+T
Sbjct: 2065 IDK-YARLDAPEREYEKPQWVQGFENYENVGEGQTVT 2100
Score = 46.0 bits (104), Expect = 3e-04
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L+++NVKK + Y + +G A P +K+ PQ PL+++ V + +
Sbjct: 3363 LRVSNVKKDNKNIYW----SEQGGAVQP-------KQKQAPQFTIPLRNLQVTENQPARF 3411
Query: 755 SAQVVGNPRPTITWCKN-NKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENSEG 812
V G PRP +TW N N+ + K + D H +T+ K ++ D G A N+EG
Sbjct: 3412 ECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSK-SRISDAGEVVAIARNTEG 3470
Query: 813 IAETSAVITV 822
++A + +
Sbjct: 3471 ETISTATLDI 3480
Score = 45.6 bits (103), Expect = 4e-04
Identities = 42/192 (21%), Positives = 82/192 (42%), Gaps = 15/192 (7%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P + L++Q+V +G + E +LT D V W DG+E+ ++ + T+ L
Sbjct: 367 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 426
Query: 1164 KIYDCDLDDAGEYSC----EVGNSKCTAILTV-----EEPSINFTLRLPEFILVPANTDA 1214
I +D+G YSC ++G S+ A + + ++ + F ++ F +
Sbjct: 427 DIPQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRS 486
Query: 1215 YLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
+ I D TL V+W K + + + + + +L + +D YTCVL
Sbjct: 487 FFEARIQPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLF 546
Query: 1272 DAKSTTKLKVEV 1283
++ + E+
Sbjct: 547 NSHGQAQSSAEL 558
Score = 45.6 bits (103), Expect = 4e-04
Identities = 55/231 (23%), Positives = 89/231 (38%), Gaps = 18/231 (7%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDF 556
EKP +E AP F+E L + + F+ +V + P +I WF+ + S F
Sbjct: 1676 EKPDAEHD--APQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRF 1733
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMT- 612
++ D ++ L I PED+G ++ A NA G A +L V L D E +
Sbjct: 1734 KLTTDFGYIS-LDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTVTGNAVILGDTQHEQSW 1792
Query: 613 ---VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAW 667
D+ G P ++ V EG E + + +P + W
Sbjct: 1793 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 1852
Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
G + + + +D + L+ T + G Y+VV N EGE
Sbjct: 1853 YLNGNPL--SASSRRILRNDFGLVSLDLQYTLGE--DAGEYSVVVKNSEGE 1899
Score = 44.8 bits (101), Expect = 7e-04
Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 17/197 (8%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE- 601
W +K S +++ +D +L I + ED+G +T V N+AG A ++ E V+
Sbjct: 1191 WLFNGNPLKASSRYRVL-NDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVDR 1249
Query: 602 --APLSD--HGSEM-TVXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLE 654
+ LSD H + + D PP F+++ + + EG + ++
Sbjct: 1250 LKSILSDTAHPESLRRIREMEQLQPAKPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMD 1309
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVV 711
C + I +P I W G ++ I +H + V L+ ++ GTYT
Sbjct: 1310 CVVQPINDPSLRIEWFHDGRPLMFGSRIRT-----IHDFGYVGLEFLHIHPEDTGTYTCK 1364
Query: 712 AVNREGEASLPIVLKIK 728
A N GEA+ I L+ K
Sbjct: 1365 ATNLIGEATTDIFLECK 1381
Score = 44.8 bits (101), Expect = 7e-04
Identities = 63/285 (22%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
K+ P ++L+ + + A +E + V W +DG+ IK +
Sbjct: 3798 KQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTN- 3856
Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE-----LPPEIITRLQNQKVNKGN 1122
L+I GEY+ L + + T E +TV P+ RL + ++ +
Sbjct: 3857 SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNG 3916
Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
A F ++ + ++WFKDG + + Q+ +G KLK + DAG Y
Sbjct: 3917 PAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAK 3976
Query: 1179 -EVGNSKCTAILTV----------EEP---SINFTLRLPEFILVPANTDAYLTVE---IP 1221
VG ++C A L V E P + FT ++ + I+V A + + P
Sbjct: 3977 NGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQI-QPIVVDEGKGAQFSAQFSGFP 4035
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
D T + WY+ ++ + + + + L I +D EY
Sbjct: 4036 DPT--IRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEY 4078
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 25/223 (11%)
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD----VAILEVEINSETADVVWERDGE 1054
I + +E + V P F + L D ++ E D V +LE I T V WE +G
Sbjct: 2997 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLE-PIGDPTLRVQWEHNGH 3055
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELP----- 1106
I P N+ + L I++ D GEY C+ ++ + + VE
Sbjct: 3056 PI-PYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDA 3114
Query: 1107 PEIITRLQNQKVN--KGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
P+++ +L + N +G+ E +T D V W ++G+ + ++ + T +
Sbjct: 3115 PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFV 3174
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK-----CTAILTVEEPSINFT 1199
L I +D G+Y V N K T I + PS+++T
Sbjct: 3175 SLDILYAYPEDNGDYELVVRNDKGEARSKTKITVLPRPSLDYT 3217
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P I +L + +G+ F E+ + V+W G I SN+++++ DGK+ L++
Sbjct: 4128 PHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILEL 4187
Query: 1166 YDCDLDDAGEYSCEVGNSKCTA 1187
D AGEY + N K A
Sbjct: 4188 ARVTPDSAGEYQIVIRNDKGAA 4209
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGSTVQFECQVEGYPRPQIT--WFR 545
++I+ E +E + AP FV +L +G + E QVE Q+T WF
Sbjct: 1532 QEIENREKLEAVDAEPEKTAPKFVTQLNSSLGELQEGVPIHLEAQVEPTNDNQLTVQWFH 1591
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ F+ +D VA L I F +D G + CVA+N+ G A + V
Sbjct: 1592 NGQPLANGHRFRTRHDFGYVA-LDILYAFAQDTGEWACVARNSLGEAQTIANFTV 1645
Score = 43.6 bits (98), Expect = 0.002
Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 24/247 (9%)
Query: 490 EKIDKLPVFEKPTSEEQSMA---PIFVEKLRPKH-TPDGSTVQFECQVEGY--PRPQITW 543
+KI + P EE + P FV +L +G FE Q + P+ + W
Sbjct: 1793 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 1852
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-- 601
+ + S ++ +D + +L ++ EDAG ++ V KN+ G ++ +L
Sbjct: 1853 YLNGNPLSASSR-RILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTR 1911
Query: 602 -APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD------EGSDILLE 654
A L D E + EG P + K Q + EGS LLE
Sbjct: 1912 AAILGDTQHEQSWQRIQEIEAPRAPGAEPEG--PVYEKPSFVQPLQSVGDLPEGSVALLE 1969
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
RLV + +P+ + W + + ++ IS + + C L+I V G Y+ A
Sbjct: 1970 ARLVPVNDPNLRVQWFYNDQPLMESNWISTSND----FGCVSLRIAPVYARHTGVYSCKA 2025
Query: 713 VNREGEA 719
N G A
Sbjct: 2026 WNDSGNA 2032
Score = 43.2 bits (97), Expect = 0.002
Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 18/223 (8%)
Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P FV++L P +G V E QV +T W + + F + D +A
Sbjct: 1022 PAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRFVLSQDFGYIA 1081
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMTVXXXXXXXXXX 623
L I +PED GT+T V +N AG A ST ++ +D ++
Sbjct: 1082 -LNILYCYPEDNGTYTLVVRNRAGEAQSTVDINCGHTGGNFTDSFHPNSLHRIAELETPI 1140
Query: 624 XXADIL---EGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVP 676
A+ L E PT +K A V E + LE ++ I + + WLF G +
Sbjct: 1141 QRAEPLPDKEKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKA 1200
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
V +D L I + G YT+V N G A
Sbjct: 1201 SSRYRVL--NDFGFVS--LDIDYIIAEDSGKYTLVVYNSAGRA 1239
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT--ITWCKNNKPV-KALPTKSDGDTH 787
E + PQ IEPL S+ + +S +V P I W K+ +P+ + K D
Sbjct: 1681 EHDAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFG 1740
Query: 788 SITILKPKKV-KDEGVYTLKAENSEGIAETSAVITV 822
I++ V +D GVY++KA N++G AE A +TV
Sbjct: 1741 YISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTV 1776
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 821 TVEEPTEENA-EPPLFINRFQ-EITVKEKGTIKLVARVT-RNPVP-SITWYRNNEIISPS 876
+VE P E N+ E P F +I V E + AR+ N V ++ WY N + +
Sbjct: 593 SVERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAA 652
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
FD + L + + DSG Y VA N G++ + + EKV +++
Sbjct: 653 HRFHPMFDFGYVALDLLYAYPQ-DSGTYTLVARNELGEARSNVELVVGTEKVLYLE 707
Score = 41.5 bits (93), Expect = 0.006
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 1285 EFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E P + +E + G VTL LV+ P EW++N ++ + + +
Sbjct: 2079 EKPQWVQGFENYENVGEGQTVTLHGLVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN 2138
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
A LTI V D+G+Y R N G A VT
Sbjct: 2139 AILTIVHVLPHDSGVYTCRAWNTQGEASTSATVT 2172
Score = 41.5 bits (93), Expect = 0.006
Identities = 53/264 (20%), Positives = 93/264 (35%), Gaps = 25/264 (9%)
Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
E+++ Q+ Q KL + + +E AP F +L+ +G +FE QV
Sbjct: 3229 ESHFKQHSQAKLQLTANDI------YNESDKRAPEFRTQLQNIGVLEGEFCRFETQVAPI 3282
Query: 537 PRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
P ++ WF+ + F+ D A L + P+D G + CVA N G
Sbjct: 3283 NDPYLKVEWFKDKKPVLLGHRFRSTLDF-GFACLDLLYALPDDTGEYHCVATNRHGQTMI 3341
Query: 595 TTELIVEAPL-----SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP------KAQ 643
+ +L + S + V ++ + P + P +
Sbjct: 3342 SAKLACQGASHVITDSQMPQGLRVSNVKKDNKNIYWSEQGGAVQPKQKQAPQFTIPLRNL 3401
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V E EC + P P + W G + + + + ++ S +I++
Sbjct: 3402 QVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDA--- 3458
Query: 704 QEGTYTVVAVNREGEASLPIVLKI 727
G +A N EGE L I
Sbjct: 3459 --GEVVAIARNTEGETISTATLDI 3480
Score = 41.1 bits (92), Expect = 0.008
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSI 789
PPQ + +S+ + E+V SA+VVG P P++TW K++ V ++ D
Sbjct: 67 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGR 126
Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETS 817
I++ D +Y L A N G ++S
Sbjct: 127 LIIEKVDAHDADMYMLVARNDGGSFQSS 154
Score = 40.7 bits (91), Expect = 0.011
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P + I R++ Q + K T + T + ++WFKDG + SN +LT D L I
Sbjct: 1690 PLDSIDRMEFQSAHFQTKVTPQ---TDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDI 1746
Query: 1166 YDCDLDDAGEYSCEVGNSK 1184
+D+G YS + N+K
Sbjct: 1747 AHTVPEDSGVYSVKASNAK 1765
Score = 40.3 bits (90), Expect = 0.015
Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%)
Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVV--GNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
PP+ + L S+ V +G+ AQ + +P+ ++ W N P+ A + + +
Sbjct: 1815 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 1874
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVIT----------------------VEEPT 826
L + +D G Y++ +NSEG TS ++ +E P
Sbjct: 1875 SLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTRAAILGDTQHEQSWQRIQEIEAPR 1934
Query: 827 EENAEP-------PLFINRFQEITVKEKGTIKLV-ARV--TRNPVPSITWYRNNEIISPS 876
AEP P F+ Q + +G++ L+ AR+ +P + W+ N++ + S
Sbjct: 1935 APGAEPEGPVYEKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMES 1994
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I+ + D + L I V + +G Y C A N +G + A V +
Sbjct: 1995 NWISTSNDFGCVSLRIAPVYAR-HTGVYSCKAWNDSGNAVTSANVGV 2040
Score = 39.9 bits (89), Expect = 0.019
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 526 TVQFECQVEGYPRPQITWFRQT-AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
TV F +V G P P +TW + +I+ +++ D L+I +V DA + V
Sbjct: 84 TVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRLIIEKVDAHDADMYMLV 143
Query: 585 AKNAAGFASSTTE 597
A+N G S+ +
Sbjct: 144 ARNDGGSFQSSVD 156
Score = 39.5 bits (88), Expect = 0.026
Identities = 74/336 (22%), Positives = 128/336 (38%), Gaps = 45/336 (13%)
Query: 709 TVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPT 765
T+ V++ + P+ L+ + K P+ L+S + +G+S L + V +P
Sbjct: 212 TLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLR 271
Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
I W N K + A + T +D ++ I P V D+G YT+ A N G A SA I V
Sbjct: 272 IAWLLNGKGILASSRIVTFTDFGIAALEI-NPVNVFDQGEYTVVAVNPLGEARVSANIAV 330
Query: 823 --------------------------EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
+ P + + P F + + V E I L ++
Sbjct: 331 IGHGSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKL 390
Query: 857 T--RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
T +P + W + + ++ Q L I S DSG Y C A N G+
Sbjct: 391 TPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSN-DSGLYSCRAFNKLGE 449
Query: 915 SSHGARVTI---DVEKVT--FVKHLQKSY-ETEEGKTVI---LECQTSHTVSTKWYHNKK 965
S + A + I + +T F+ +Q + E E G++ ++ T+ W + +
Sbjct: 450 SENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQ 509
Query: 966 EISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
+ + +I Q D GV C++
Sbjct: 510 PLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVL 545
Score = 39.5 bits (88), Expect = 0.026
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
Q+P PL+N+ N+ C G P+PKVTW+ +G +
Sbjct: 3390 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQ 3431
Score = 39.5 bits (88), Expect = 0.026
Identities = 21/78 (26%), Positives = 36/78 (46%)
Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
++G V + P+P +W K I + K S D K A L + +V AG Y+
Sbjct: 4140 RQGHTVKFSAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQ 4199
Query: 1360 LRLENNCGHADVEMNVTI 1377
+ + N+ G A + +T+
Sbjct: 4200 IVIRNDKGAATSQAKLTL 4217
Score = 39.1 bits (87), Expect = 0.034
Identities = 58/279 (20%), Positives = 103/279 (36%), Gaps = 22/279 (7%)
Query: 490 EKIDKLPVFEKPT-SEEQSMAPIF-----VEKLRPKHTPDGSTVQFECQVEGY--PRPQI 541
E ++ + E P +E ++ AP++ ++ K +G V FE + PR Q+
Sbjct: 2319 ESWKRIQILEAPKEAEPEAPAPVYDHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQV 2378
Query: 542 TWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV- 600
W R + + + D + TL + +PED G + N G A S+ L
Sbjct: 2379 QWIRNGVPLAHGSKYAIQ-QDFGICTLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCH 2437
Query: 601 --EAPLSD---HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLE 654
+A L D S + AD PP F ++ + E E
Sbjct: 2438 GKDAILGDVQHQESWKRIQEIEAPKQKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFE 2497
Query: 655 CRLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
+ + +P I W GE + + + +D ++ I + G + VA
Sbjct: 2498 ATVEPVDDPTLTINWFLNGEPMSASSRVKMI--NDFGWV--IMDIAQTEPRDSGEWKCVA 2553
Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
N GEA ++++ E ++P +RQ E+
Sbjct: 2554 KNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEA 2592
Score = 38.7 bits (86), Expect = 0.045
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 731 EKEPPQVIEPLKSMI--VRQGESVILSAQVVGNPRPTIT--WCKNNKPVKALPTKSDGDT 786
EKE P + +PL + I V + +++ L AQV T+ W N P+KA +
Sbjct: 1150 EKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKASSRYRVLND 1209
Query: 787 HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE 823
L + +D G YTL NS G AETS V+
Sbjct: 1210 FGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1248
Score = 38.7 bits (86), Expect = 0.045
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PE T+LQN V +G FE ++ D V WFKD + + + T+D L
Sbjct: 3256 PEFRTQLQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACL 3315
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
+ DD GEY C N
Sbjct: 3316 DLLYALPDDTGEYHCVATN 3334
Score = 37.9 bits (84), Expect = 0.078
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
+P + W N I S I+ + L+I ++ + D+G+YKCVA+N G ++
Sbjct: 3043 DPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAA-DAGEYKCVATNVKGSATSV 3101
Query: 919 ARVTID----VEKVTFVKHLQKSYET-EEGKTVILECQTS 953
++ ++ ++ V+ L S E EG ++ LEC+ +
Sbjct: 3102 GKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVT 3141
Score = 37.5 bits (83), Expect = 0.10
Identities = 19/79 (24%), Positives = 37/79 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P V+W +GN+L ++ +Y T + + I + + S Y+ A N G S + T
Sbjct: 396 PDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSNDSGLYSCRAFNKLGESENQAT 455
Query: 1660 LKVYDKPSKPEGPVIMREI 1678
+ ++ S+ P + +I
Sbjct: 456 IIIFAHSSQDLTPKFLSQI 474
Score = 37.5 bits (83), Expect = 0.10
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNN 772
E EA P + PP+ L +++G+ L QV V +PR I W N
Sbjct: 2859 EIEAPRPAREDAPDADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNG 2918
Query: 773 KPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+PV K+ D + + L P + +D G +T +A N G E S + V
Sbjct: 2919 QPVNHTNRMKAIHDFGFVVLQLTPAEPQDSGTWTCRATNQHGSDEVSTELKV 2970
Score = 37.1 bits (82), Expect = 0.14
Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 1107 PEIITRLQNQ-KVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
P I+ LQ Q + +G A + + T V W KDG I SN ++ D
Sbjct: 2608 PAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHSNRYKMVHDFGFAV 2667
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIP 1221
L I DAGEY+ V N+ A S +F + IL P N VEI
Sbjct: 2668 LDILHLLKHDAGEYTFRVSNNSGEA-----STSTSFEVSESSGLILQPQNEQKAKAVEIL 2722
Query: 1222 DETL 1225
++ L
Sbjct: 2723 EDNL 2726
Score = 36.3 bits (80), Expect = 0.24
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDGD 785
+PP E L ++G+S+ L ++ V +P +TW +N +P+ + +P ++ D
Sbjct: 1418 QPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPLPEASRFMPARNF-D 1476
Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++ IL +D GVYT KA ++ G A TS +
Sbjct: 1477 YVNLDILALYG-EDSGVYTCKAVSAFGEAATSCTV 1510
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P + W+K+G L N + +TT + I S Y+++ASN G + V+
Sbjct: 1714 PNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQ 1773
Query: 1660 LKV 1662
L V
Sbjct: 1774 LTV 1776
Score = 36.3 bits (80), Expect = 0.24
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
+P ++ A P F + + V E + VT P P +TW+ N NF
Sbjct: 3385 QPKQKQA--PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNF 3442
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
DG + + + D+G+ +A N+ G++ A + I
Sbjct: 3443 DG--LHYLTVSKSRISDAGEVVAIARNTEGETISTATLDI 3480
Score = 35.9 bits (79), Expect = 0.32
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870
+ E E+P E+ + P FI I E + +VT P+ I W+++
Sbjct: 1666 VLEAPRAAAPEKPDAEH-DAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDG 1724
Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ + S D I L I + E DSG Y ASN+ G + A++T+
Sbjct: 1725 QPLMNSNRFKLTTDFGYISLDIAHTVPE-DSGVYSVKASNAKGDAEVQAQLTV 1776
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P +V W K+G + + Y + +V+ I L + + +YT SN +G +S +
Sbjct: 2638 PSIKVEWLKDGQPIFHSNRYKMVHDFGFAVLDILHLLKHDAGEYTFRVSNNSGEASTSTS 2697
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIE 1686
+V S+ G ++ + +++ +E
Sbjct: 2698 FEV----SESSGLILQPQNEQKAKAVE 2720
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASL 1345
PK + ++ G L + Y PN W++N K I D A+L
Sbjct: 239 PKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILASSRIVTFTDFGIAAL 298
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
I V D G Y + N G A V N+ ++
Sbjct: 299 EINPVNVFDQGEYTVVAVNPLGEARVSANIAVI 331
Score = 33.1 bits (72), Expect = 2.2
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 1106 PPEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
PP+ +T+L + V +G + FE I + V+W+ +G+ + S+ L D
Sbjct: 1815 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 1874
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK 1184
L + +DAGEYS V NS+
Sbjct: 1875 SLDLQYTLGEDAGEYSVVVKNSE 1897
Score = 32.7 bits (71), Expect = 3.0
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 7/116 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKN 771
R+ EA P + + E P ++ L+ + +G S L Q V +P + W K+
Sbjct: 2588 RQIEAGKPAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKD 2647
Query: 772 NKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
+P+ D + IL K D G YT + N+ G A TS V E
Sbjct: 2648 GQPIFHSNRYKMVHDFGFAVLDILHLLK-HDAGEYTFRVSNNSGEASTSTSFEVSE 2702
Score = 32.3 bits (70), Expect = 3.9
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 735 PQVIEPLKSMIVRQGES--VILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITI 791
P+ + L + + + E+ V L A V +P I W N +P+ K+ + I +
Sbjct: 740 PKFLNDLPDIQLNEHENIHVDLRATPVNDPTMVIEWFVNGRPLLTGSRVKTLNEFGFIAL 799
Query: 792 -LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+K +D G Y+++A N G A VITV
Sbjct: 800 DIKGAIAEDSGTYSVRASNLLGEAIRQCVITV 831
Score = 32.3 bits (70), Expect = 3.9
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTIT--WCKN 771
+E EA P ++ +PP ++ L I +G++V L AQV ++T W N
Sbjct: 1002 QEIEAPKPAPQEVPDLPHQPPAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVN 1061
Query: 772 NKPV-KA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
+P+ KA D ++ IL +D G YTL N G A+++ I
Sbjct: 1062 GQPLMKAHRFVLSQDFGYIALNILYCYP-EDNGTYTLVVRNRAGEAQSTVDI 1112
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
+A ++G P P V W G + I+ K +++ + + + +Y I N G
Sbjct: 4148 SAEVDGNPEPTVQWQFKGKPISASNNVKISRDGKRAILELARVTPDSAGEYQIVIRNDKG 4207
Query: 1653 --TSSVEVTL 1660
TS ++TL
Sbjct: 4208 AATSQAKLTL 4217
Score = 31.1 bits (67), Expect = 9.0
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Query: 746 VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDE 800
V +GE + L QV + + I W ++ + + T D S+ IL +D
Sbjct: 902 VEEGEPIHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFYDFGFVSLDILG-FYAQDA 960
Query: 801 GVYTLKAENSEGIAETSAVI 820
G YT +AENS G AET A I
Sbjct: 961 GTYTCRAENSLGQAETVATI 980
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/66 (24%), Positives = 29/66 (43%)
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
Q P +W + + + K + D SL I D+G+Y ++ N G A+V
Sbjct: 1711 QTDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEV 1770
Query: 1372 EMNVTI 1377
+ +T+
Sbjct: 1771 QAQLTV 1776
Score = 31.1 bits (67), Expect = 9.0
Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ G P P+V W+ NGN+ + + + + + + + + S + + A NT G +
Sbjct: 3415 VTGYPRPKVTWFINGNQCLHGHRFKLNF-DGLHYLTVSKSRISDAGEVVAIARNTEGETI 3473
Query: 1656 VEVTLKVY 1663
TL ++
Sbjct: 3474 STATLDIF 3481
>U88183-2|AAM69080.1| 1273|Caenorhabditis elegans Sensory axon
guidance protein 3,isoform b protein.
Length = 1273
Score = 99.5 bits (237), Expect = 2e-20
Identities = 100/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)
Query: 636 FSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
F +P+ G +LEC PEP ++W +E+ + + SD ++
Sbjct: 135 FRVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI--- 191
Query: 695 LKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
I V + GTY VA N GE S P L + E P+ + K M V G +V+
Sbjct: 192 --IDPVDRSDSGTYQCVANNMVGERVSNPARLSVF----EKPKFEQEPKDMTVDVGAAVL 245
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
+V G+P+P ITW + N+P+ D + I + + DEG Y A N G
Sbjct: 246 FDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIERVQP-SDEGEYVCYARNPAGT 304
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNE 871
E SA + V+ PP F + + +V GT + P P+ W + +
Sbjct: 305 LEASAHLRVQ-------APPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQD 357
Query: 872 IISPSETITQNFDGENIELVITNVD-SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT- 929
++ PS + +T + ++D G Y C NSAG S A + + + VT
Sbjct: 358 LLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTG 417
Query: 930 --------FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG 979
++H ++ G + IL CQ S T W + I D R I +
Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSR--ISQH 475
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
D GV CI K+++ + T+ + Q
Sbjct: 476 STGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQ 520
Score = 93.1 bits (221), Expect = 2e-18
Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 28/303 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F ++PK VD G+ +L +CR+ P+P I W K E +P +A ++
Sbjct: 227 PKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP-MPVTRAYIAKDN------R 279
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L+I V+ EG Y A N G L+++ PP V G +
Sbjct: 280 GLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQA----PPSFQTKPADQSVPAGGTAT 335
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPT--KSDG-----DTHSITILKPKKVKDEGVYTLK 806
+VG P P W K + P+ +DG T ++TI + ++V DEG Y
Sbjct: 336 FECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQV-DEGAYVCA 394
Query: 807 AENSEG--IAETSAVITVEEPTEEN-AEPPLFINR-FQEITVKEKGTIKLVARVTRNPVP 862
NS G +++ + +T + T A+PP I Q T+ + L + + P P
Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454
Query: 863 SITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
I+W R+ I +++ I+Q+ G L I ++ + D+G Y C+A N G+S+ A +
Sbjct: 455 GISWLRDGLPIDITDSRISQHSTG---SLHIADL-KKPDTGVYTCIAKNEDGESTWSASL 510
Query: 922 TID 924
T++
Sbjct: 511 TVE 513
Score = 93.1 bits (221), Expect = 2e-18
Identities = 66/207 (31%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP+F KP Q V G EC LV P P W +G++ + + A
Sbjct: 316 PPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPT 375
Query: 693 SVLKITNVKKFQEGTYTVVAVNREG----EASLPIVLKIKTGE---KEPPQVIEPLKSMI 745
L I V++ EG Y +N G +A+L + K TG K PP + ++
Sbjct: 376 GTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQT 435
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804
+ G S IL Q G P P I+W ++ P+ ++ S T S+ I KK D GVYT
Sbjct: 436 LMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKK-PDTGVYT 494
Query: 805 LKAENSEGIAETSAVITVEEPTEENAE 831
A+N +G + SA +TVE+ T NA+
Sbjct: 495 CIAKNEDGESTWSASLTVEDHT-SNAQ 520
Score = 78.6 bits (185), Expect = 5e-14
Identities = 126/603 (20%), Positives = 223/603 (36%), Gaps = 62/603 (10%)
Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTEKFT---LISDVKKRTLII--- 1255
P ++V + A L T +TWYK + VI + E+ ++ D L+
Sbjct: 37 PIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNS 96
Query: 1256 -RKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR--GSDVTLLV--D 1310
+ + D Y CV + K ++ D+ R + G ++ +L
Sbjct: 97 GKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMAVLECSP 156
Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH-A 1369
+ FP+P W + K ++ + ++ S +L I V+ +D+G Y+ N G
Sbjct: 157 PRGFPEPVVSWRKDDKELRIQDMPRYTLHS-DGNLIIDPVDRSDSGTYQCVANNMVGERV 215
Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
+++ +KP +P + +D + + +D I + + + + T
Sbjct: 216 SNPARLSVFEKPKFEQEPKDMTVDVGAA-VLFDCRVTGDPQPQITWKRKNEPMPVTRAYI 274
Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
K+ I+ ++ + + YA N +AS + +V Q+ ++ +
Sbjct: 275 AKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASA---HLRVQAPPSFQTKPADQSVP 329
Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK--LKTAKATYENRXXXXXXXXXXXXXX- 1546
T E C G P P W ++G++ L + + + R
Sbjct: 330 AGGTATFE-----CTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVR 384
Query: 1547 -----XYKCIAFNDHG--------EVETSCVVG-IQQKPVITISNEDIKQKHKVGDEWLV 1592
Y C N G +V T V G KP TI + Q VG ++
Sbjct: 385 QVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAIL 444
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
G P P + W ++G L D + ++ T + I +LK+ + YT A N G
Sbjct: 445 PCQASGKPTPGISWLRDG--LPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDG 502
Query: 1653 TSSVEVTLKVYDK---------------PSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
S+ +L V D PS P P+I+ ++ V + W P G
Sbjct: 503 ESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIV-NVTDTEVELHWNAPSTSGAGP 561
Query: 1698 LTKYAIEKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
+T Y I+ + PD W + D E Y I+ L + YMF + A+N G S
Sbjct: 562 ITGYIIQYYSPDLGQTWFNIPDYVASTE-YRIKGLKPSHSYMFVIRAENEKGIGTPSVSS 620
Query: 1757 PIV 1759
+V
Sbjct: 621 ALV 623
Score = 72.5 bits (170), Expect = 3e-12
Identities = 135/617 (21%), Positives = 231/617 (37%), Gaps = 82/617 (13%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542
+E P+ ++ L C G P K+TWY+DG+ + T K +
Sbjct: 34 IEHPI-DVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90
Query: 1543 ------------XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK----V 1586
Y C+A N+HGEV+++ + + + ED + + + +
Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSN-----EGSLKLAMLREDFRVRPRTVQAL 145
Query: 1587 GDEWLVTAVI--EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G E V G P P V W K+ +L T ++I I + RS S Y
Sbjct: 146 GGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI-IDPVDRSDSGTYQ 204
Query: 1645 IEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
A+N G S L V++KP + P M +V + + D K
Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWK--- 261
Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA-----LESEPI 1758
K+EP +A +R + +Q +E EY+ A+NP G EA +++ P
Sbjct: 262 RKNEPMPVTRAYIAKDNRGLRIERVQPSDEG-EYV--CYARNPAGTLEASAHLRVQAPPS 318
Query: 1759 VIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
D VP+ + S W K G ++ + + +G+ K
Sbjct: 319 FQTKPADQSVPAGGTATFECTLVGQPSPAYFW---SKEGQQDLL-FPSYVSADGRT-KVS 373
Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
++++ + N G+SL + T T P++P +
Sbjct: 374 PTGTLTIEEVRQVDEGA---YVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHG 430
Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK----IVTVGGSVHEHC-----I 1927
++++ + G S I K G SW + I + +H I
Sbjct: 431 HQNQTLMV--------GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHI 482
Query: 1928 ENIKEKDEIIFRISAENTVG-----VSLPTE-----SQSVRLEKHATVPSPPTAPLEIRM 1977
++K+ D ++ A+N G SL E +Q VR+ + PS PT P+ + +
Sbjct: 483 ADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIVNV 542
Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ + + W P G P+ GY I D+ +T W + +T ++ I+ L +H
Sbjct: 543 TDTEVEL-HWNAPSTSGAGPITGYIIQYYSPDLGQT-WFNIPDYVAST-EYRIKGLKPSH 599
Query: 2036 TYMIRIYARNEIGLSEP 2052
+YM I A NE G+ P
Sbjct: 600 SYMFVIRAENEKGIGTP 616
Score = 68.9 bits (161), Expect = 4e-11
Identities = 134/623 (21%), Positives = 222/623 (35%), Gaps = 65/623 (10%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXX 1538
+ P E+ K++T + + C G PQP++TW R + + +A ++
Sbjct: 225 EKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIE 284
Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
Y C A N G +E S + +Q P D Q G + G
Sbjct: 285 RVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPAD--QSVPAGGTATFECTLVG 342
Query: 1599 IPPPEVIWYKNGNKLENDKEY----NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
P P W K G + Y T T + I+E+++ Y N+AG+S
Sbjct: 343 QPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSS 402
Query: 1655 SVEVTLKVYDK------PSKPEGPVIMREISRESVTI----------EWKPP-----LDD 1693
+ LKV K P+KP P I +++ + KP L D
Sbjct: 403 LSKAALKVTTKAVTGNTPAKPP-PTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRD 461
Query: 1694 G-GLELTKYAIEKHEPDNNRWIKVADVDR-DVETY-CIQKLNENCEYMFRVIAQNPVGFS 1750
G +++T I +H + + +AD+ + D Y CI K NE+ E + S
Sbjct: 462 GLPIDITDSRISQHSTGS---LHIADLKKPDTGVYTCIAK-NEDGESTWSASLTVEDHTS 517
Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE- 1809
A + + + + PS D E V + W +G PI Y ++
Sbjct: 518 NA---QFVRMPDPSNFPSSPTQPIIVNVTDTE-VELHWNAPSTSGAGPITGYIIQYYSPD 573
Query: 1810 -GKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-----T 1862
G+ W RI+ L + +Y F I A NE G P S +T K
Sbjct: 574 LGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPSVSSALVTTSKPAAQVA 633
Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP-------------ITNYIIEFKTVKG 1909
L+ ++ + + + +K E ++ + I Y I+++
Sbjct: 634 LSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAVRLFWKKRKLEELIDGYYIKWRGPPR 693
Query: 1910 KSWTKIVTV-GGSVHEHCIENIKE-KDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
+ + V V S + + N+ + F I + V S S+ + PS
Sbjct: 694 TNDNQYVNVTSPSTENYVVSNLMPFTNYEFFVIPYHSGVHSIHGAPSNSMDVLTAEAPPS 753
Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
P + IRM+ + SW P+ DG L G+ I I + +
Sbjct: 754 LPPEDVRIRMLNLTTLRISWKAPKADGINGILKGFQIVIVGQAPNNNRNI-TTNERAASV 812
Query: 2027 NIRDLSENHTYMIRIYARNEIGL 2049
+ L TY IR+ AR+ G+
Sbjct: 813 TLFHLVTGMTYKIRVAARSNGGV 835
Score = 65.3 bits (152), Expect = 5e-10
Identities = 107/496 (21%), Positives = 183/496 (36%), Gaps = 43/496 (8%)
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI-----QFSNHIQLTIDGK 1159
L P II + V++G+ AT A + W+KDG + Q ++H + G
Sbjct: 29 LAPVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGS 88
Query: 1160 KQKLKI---YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD--- 1213
LK+ + DAG Y C N + E S+ + +F + P
Sbjct: 89 LFLLKVNSGKNGKDSDAGAYYCVASNEH--GEVKSNEGSLKLAMLREDFRVRPRTVQALG 146
Query: 1214 ---AYLTVEIPDETLD--VTWYK--KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
A L P + V+W K K+ I+D ++TL SD LII D Y
Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSD---GNLIIDPVDRSDSGTY 203
Query: 1267 TCV---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV ++ + + ++ V E PK ++ + G+ V PQP W
Sbjct: 204 QCVANNMVGERVSNPARLSVFE-KPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITW-- 260
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
+ + T+ I + L I++V+ +D G Y N G + ++ + PS
Sbjct: 261 -KRKNEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSF 319
Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE--YQEIDTTEWISVKNITKTQ---- 1437
KP + + E G + Y+ + Q++ ++S TK
Sbjct: 320 QTKPADQSVPAG--GTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGT 377
Query: 1438 TSIQNLKTNSSYRFRAYAVNEV--DISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTE 1494
+I+ ++ + +N +S A+ V T + PT+E +N T
Sbjct: 378 LTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLM 437
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
L C G P P ++W RDG + ++ + + Y CIA
Sbjct: 438 VGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIA 497
Query: 1553 FNDHGEVETSCVVGIQ 1568
N+ GE S + ++
Sbjct: 498 KNEDGESTWSASLTVE 513
Score = 64.5 bits (150), Expect = 8e-10
Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 42/350 (12%)
Query: 864 ITWYRNNE-IISPSETITQN---FDGENIELVITNVDS---EIDSGDYKCVASNSAG--K 914
ITWY++ + +I+ E + + D ++ L+ N + D+G Y CVASN G K
Sbjct: 61 ITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVK 120
Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKE--ISG 969
S+ G+ + + + + F + ++ + G+ +LEC W + KE I
Sbjct: 121 SNEGS-LKLAMLREDF-RVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQD 178
Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ-----ETSTMLVVKETIPEFIRKLQ 1024
M + +G D G +C+ + L V E P+F ++ +
Sbjct: 179 MPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARLSVFEK-PKFEQEPK 234
Query: 1025 DFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
D V + + + + + W+R E + + + RG L I D
Sbjct: 235 DMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRG----LRIERVQPSD 290
Query: 1084 EGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139
EGEY C R+ + T E + V+ PP T+ +Q V G ATFE L + W
Sbjct: 291 EGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFW 350
Query: 1140 FKDG-SEIQFSNHIQLTIDGKKQ-----KLKIYDCDLDDAGEYSCEVGNS 1183
K+G ++ F +++ + DG+ + L I + D G Y C NS
Sbjct: 351 SKEGQQDLLFPSYV--SADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNS 398
Score = 62.5 bits (145), Expect = 3e-09
Identities = 60/223 (26%), Positives = 84/223 (37%), Gaps = 30/223 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQ-DFQMYYDDDNVA 566
P F K + P G T FEC + G P P W + Q ++ PS
Sbjct: 317 PSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTG 376
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
TL I EV D G + C N+AG + S L V
Sbjct: 377 TLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKV-------------------TTKAVTG 417
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIE 685
+ PPT + Q + GS +L C+ P P I+WL G I + D IS
Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHST 477
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
+H I ++KK G YT +A N +GE++ L ++
Sbjct: 478 GSLH-------IADLKKPDTGVYTCIAKNEDGESTWSASLTVE 513
Score = 61.7 bits (143), Expect = 6e-09
Identities = 101/466 (21%), Positives = 181/466 (38%), Gaps = 60/466 (12%)
Query: 1047 VVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-----SCTAEV 1100
V W +D + ++ + +Y G+ L I D G Y C+ + S A +
Sbjct: 165 VSWRKDDKELRIQDMPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARL 221
Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDG 1158
+V E P+ ++ V+ G F+ +T GD + W + + + + I
Sbjct: 222 SVFE-KPKFEQEPKDMTVDVGAAVLFDCRVT-GDPQPQITWKRKNEPMPVT---RAYIAK 276
Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
+ L+I D GEY C G + +A L V+ P +F + P VPA A
Sbjct: 277 DNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPP-SFQTK-PADQSVPAGGTA 334
Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR-----TLIIRKCTEDDQCEYTCV 1269
+ + ++ K+ + + +D + + TL I + + D+ Y C
Sbjct: 335 TFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCA 394
Query: 1270 LLDA------KSTTKLKVEVV------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+++ K+ K+ + V + PP I + + GS L P P
Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
W+ + I T I S SL I ++ D G+Y +N G + ++T
Sbjct: 455 GISWLRDGLPIDI---TDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLT 511
Query: 1377 ILDK---------------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
+ D PS P +P I+ + + + + W+ P +G I Y+++Y
Sbjct: 512 VEDHTSNAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTSGAGPITGYIIQYYS 571
Query: 1422 IDTTE-WISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
D + W ++ + + T+ I+ LK + SY F A NE I S
Sbjct: 572 PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPS 617
Score = 61.7 bits (143), Expect = 6e-09
Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 20/135 (14%)
Query: 476 DENNYTQYLQKKLNEKID---KLPVFEKPTSEEQSMAPIFVEKLRPKH-TPD-GSTVQFE 530
D Y + E++ +L VFEKP E++ PK T D G+ V F+
Sbjct: 199 DSGTYQCVANNMVGERVSNPARLSVFEKPKFEQE-----------PKDMTVDVGAAVLFD 247
Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
C+V G P+PQITW R+ +P + Y DN L I V P D G + C A+N AG
Sbjct: 248 CRVTGDPQPQITWKRKN---EPMPVTRAYIAKDN-RGLRIERVQPSDEGEYVCYARNPAG 303
Query: 591 FASSTTELIVEAPLS 605
++ L V+AP S
Sbjct: 304 TLEASAHLRVQAPPS 318
Score = 54.8 bits (126), Expect = 6e-07
Identities = 84/403 (20%), Positives = 142/403 (35%), Gaps = 42/403 (10%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK----RGHIR 1072
P I D V A L TA + W +DG+ + K + + + G +
Sbjct: 31 PVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90
Query: 1073 KLYI---RNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124
L + +N D G Y C+ +E S + + L + R + + G A
Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMA 150
Query: 1125 TFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
E +G + +V W KD E++ + + T+ L I D D+G Y C N
Sbjct: 151 VLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLH-SDGNLIIDPVDRSDSGTYQCVANN 209
Query: 1183 ------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSV 1235
S + E+P + P+ + V + D +TW +K
Sbjct: 210 MVGERVSNPARLSVFEKPKFE---QEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP 266
Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYE 1294
+ T + + D R L I + D+ EY C + T + + V+ PP
Sbjct: 267 MPVTRAY-IAKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKP 323
Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEW-------IVNSKIIKKCKHTKPSIDSKSASLTI 1347
+ + G T P P W ++ + TK S + +LTI
Sbjct: 324 ADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKV---SPTGTLTI 380
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKP 1387
++V D G Y N+ G + + + + K + P KP
Sbjct: 381 EEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKP 423
Score = 36.7 bits (81), Expect = 0.18
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 524 GSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGT 580
G EC G+P P ++W + ++ QD Y + D N L+I V D+GT
Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELR-IQDMPRYTLHSDGN---LIIDPVDRSDSGT 202
Query: 581 FTCVAKNAAG 590
+ CVA N G
Sbjct: 203 YQCVANNMVG 212
>U88183-1|AAB52657.2| 1269|Caenorhabditis elegans Sensory axon
guidance protein 3,isoform a protein.
Length = 1269
Score = 99.5 bits (237), Expect = 2e-20
Identities = 100/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)
Query: 636 FSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
F +P+ G +LEC PEP ++W +E+ + + SD ++
Sbjct: 135 FRVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI--- 191
Query: 695 LKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
I V + GTY VA N GE S P L + E P+ + K M V G +V+
Sbjct: 192 --IDPVDRSDSGTYQCVANNMVGERVSNPARLSVF----EKPKFEQEPKDMTVDVGAAVL 245
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
+V G+P+P ITW + N+P+ D + I + + DEG Y A N G
Sbjct: 246 FDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIERVQP-SDEGEYVCYARNPAGT 304
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNE 871
E SA + V+ PP F + + +V GT + P P+ W + +
Sbjct: 305 LEASAHLRVQ-------APPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQD 357
Query: 872 IISPSETITQNFDGENIELVITNVD-SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT- 929
++ PS + +T + ++D G Y C NSAG S A + + + VT
Sbjct: 358 LLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTG 417
Query: 930 --------FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG 979
++H ++ G + IL CQ S T W + I D R I +
Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSR--ISQH 475
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
D GV CI K+++ + T+ + Q
Sbjct: 476 STGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQ 520
Score = 93.1 bits (221), Expect = 2e-18
Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 28/303 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F ++PK VD G+ +L +CR+ P+P I W K E +P +A ++
Sbjct: 227 PKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP-MPVTRAYIAKDN------R 279
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L+I V+ EG Y A N G L+++ PP V G +
Sbjct: 280 GLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQA----PPSFQTKPADQSVPAGGTAT 335
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPT--KSDG-----DTHSITILKPKKVKDEGVYTLK 806
+VG P P W K + P+ +DG T ++TI + ++V DEG Y
Sbjct: 336 FECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQV-DEGAYVCA 394
Query: 807 AENSEG--IAETSAVITVEEPTEEN-AEPPLFINR-FQEITVKEKGTIKLVARVTRNPVP 862
NS G +++ + +T + T A+PP I Q T+ + L + + P P
Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454
Query: 863 SITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
I+W R+ I +++ I+Q+ G L I ++ + D+G Y C+A N G+S+ A +
Sbjct: 455 GISWLRDGLPIDITDSRISQHSTG---SLHIADL-KKPDTGVYTCIAKNEDGESTWSASL 510
Query: 922 TID 924
T++
Sbjct: 511 TVE 513
Score = 93.1 bits (221), Expect = 2e-18
Identities = 66/207 (31%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP+F KP Q V G EC LV P P W +G++ + + A
Sbjct: 316 PPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPT 375
Query: 693 SVLKITNVKKFQEGTYTVVAVNREG----EASLPIVLKIKTGE---KEPPQVIEPLKSMI 745
L I V++ EG Y +N G +A+L + K TG K PP + ++
Sbjct: 376 GTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQT 435
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804
+ G S IL Q G P P I+W ++ P+ ++ S T S+ I KK D GVYT
Sbjct: 436 LMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKK-PDTGVYT 494
Query: 805 LKAENSEGIAETSAVITVEEPTEENAE 831
A+N +G + SA +TVE+ T NA+
Sbjct: 495 CIAKNEDGESTWSASLTVEDHT-SNAQ 520
Score = 78.6 bits (185), Expect = 5e-14
Identities = 126/603 (20%), Positives = 223/603 (36%), Gaps = 62/603 (10%)
Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTEKFT---LISDVKKRTLII--- 1255
P ++V + A L T +TWYK + VI + E+ ++ D L+
Sbjct: 37 PIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNS 96
Query: 1256 -RKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR--GSDVTLLV--D 1310
+ + D Y CV + K ++ D+ R + G ++ +L
Sbjct: 97 GKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMAVLECSP 156
Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH-A 1369
+ FP+P W + K ++ + ++ S +L I V+ +D+G Y+ N G
Sbjct: 157 PRGFPEPVVSWRKDDKELRIQDMPRYTLHS-DGNLIIDPVDRSDSGTYQCVANNMVGERV 215
Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
+++ +KP +P + +D + + +D I + + + + T
Sbjct: 216 SNPARLSVFEKPKFEQEPKDMTVDVGAA-VLFDCRVTGDPQPQITWKRKNEPMPVTRAYI 274
Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
K+ I+ ++ + + YA N +AS + +V Q+ ++ +
Sbjct: 275 AKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASA---HLRVQAPPSFQTKPADQSVP 329
Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK--LKTAKATYENRXXXXXXXXXXXXXX- 1546
T E C G P P W ++G++ L + + + R
Sbjct: 330 AGGTATFE-----CTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVR 384
Query: 1547 -----XYKCIAFNDHG--------EVETSCVVG-IQQKPVITISNEDIKQKHKVGDEWLV 1592
Y C N G +V T V G KP TI + Q VG ++
Sbjct: 385 QVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAIL 444
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
G P P + W ++G L D + ++ T + I +LK+ + YT A N G
Sbjct: 445 PCQASGKPTPGISWLRDG--LPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDG 502
Query: 1653 TSSVEVTLKVYDK---------------PSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
S+ +L V D PS P P+I+ ++ V + W P G
Sbjct: 503 ESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIV-NVTDTEVELHWNAPSTSGAGP 561
Query: 1698 LTKYAIEKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
+T Y I+ + PD W + D E Y I+ L + YMF + A+N G S
Sbjct: 562 ITGYIIQYYSPDLGQTWFNIPDYVASTE-YRIKGLKPSHSYMFVIRAENEKGIGTPSVSS 620
Query: 1757 PIV 1759
+V
Sbjct: 621 ALV 623
Score = 72.5 bits (170), Expect = 3e-12
Identities = 135/617 (21%), Positives = 231/617 (37%), Gaps = 82/617 (13%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542
+E P+ ++ L C G P K+TWY+DG+ + T K +
Sbjct: 34 IEHPI-DVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90
Query: 1543 ------------XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK----V 1586
Y C+A N+HGEV+++ + + + ED + + + +
Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSN-----EGSLKLAMLREDFRVRPRTVQAL 145
Query: 1587 GDEWLVTAVI--EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G E V G P P V W K+ +L T ++I I + RS S Y
Sbjct: 146 GGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI-IDPVDRSDSGTYQ 204
Query: 1645 IEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
A+N G S L V++KP + P M +V + + D K
Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWK--- 261
Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA-----LESEPI 1758
K+EP +A +R + +Q +E EY+ A+NP G EA +++ P
Sbjct: 262 RKNEPMPVTRAYIAKDNRGLRIERVQPSDEG-EYV--CYARNPAGTLEASAHLRVQAPPS 318
Query: 1759 VIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
D VP+ + S W K G ++ + + +G+ K
Sbjct: 319 FQTKPADQSVPAGGTATFECTLVGQPSPAYFW---SKEGQQDLL-FPSYVSADGRT-KVS 373
Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
++++ + N G+SL + T T P++P +
Sbjct: 374 PTGTLTIEEVRQVDEGA---YVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHG 430
Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK----IVTVGGSVHEHC-----I 1927
++++ + G S I K G SW + I + +H I
Sbjct: 431 HQNQTLMV--------GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHI 482
Query: 1928 ENIKEKDEIIFRISAENTVG-----VSLPTE-----SQSVRLEKHATVPSPPTAPLEIRM 1977
++K+ D ++ A+N G SL E +Q VR+ + PS PT P+ + +
Sbjct: 483 ADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIVNV 542
Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ + + W P G P+ GY I D+ +T W + +T ++ I+ L +H
Sbjct: 543 TDTEVEL-HWNAPSTSGAGPITGYIIQYYSPDLGQT-WFNIPDYVAST-EYRIKGLKPSH 599
Query: 2036 TYMIRIYARNEIGLSEP 2052
+YM I A NE G+ P
Sbjct: 600 SYMFVIRAENEKGIGTP 616
Score = 68.9 bits (161), Expect = 4e-11
Identities = 134/623 (21%), Positives = 222/623 (35%), Gaps = 65/623 (10%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXX 1538
+ P E+ K++T + + C G PQP++TW R + + +A ++
Sbjct: 225 EKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIE 284
Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
Y C A N G +E S + +Q P D Q G + G
Sbjct: 285 RVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPAD--QSVPAGGTATFECTLVG 342
Query: 1599 IPPPEVIWYKNGNKLENDKEY----NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
P P W K G + Y T T + I+E+++ Y N+AG+S
Sbjct: 343 QPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSS 402
Query: 1655 SVEVTLKVYDK------PSKPEGPVIMREISRESVTI----------EWKPP-----LDD 1693
+ LKV K P+KP P I +++ + KP L D
Sbjct: 403 LSKAALKVTTKAVTGNTPAKPP-PTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRD 461
Query: 1694 G-GLELTKYAIEKHEPDNNRWIKVADVDR-DVETY-CIQKLNENCEYMFRVIAQNPVGFS 1750
G +++T I +H + + +AD+ + D Y CI K NE+ E + S
Sbjct: 462 GLPIDITDSRISQHSTGS---LHIADLKKPDTGVYTCIAK-NEDGESTWSASLTVEDHTS 517
Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE- 1809
A + + + + PS D E V + W +G PI Y ++
Sbjct: 518 NA---QFVRMPDPSNFPSSPTQPIIVNVTDTE-VELHWNAPSTSGAGPITGYIIQYYSPD 573
Query: 1810 -GKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-----T 1862
G+ W RI+ L + +Y F I A NE G P S +T K
Sbjct: 574 LGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPSVSSALVTTSKPAAQVA 633
Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP-------------ITNYIIEFKTVKG 1909
L+ ++ + + + +K E ++ + I Y I+++
Sbjct: 634 LSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAVRLFWKKRKLEELIDGYYIKWRGPPR 693
Query: 1910 KSWTKIVTV-GGSVHEHCIENIKE-KDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
+ + V V S + + N+ + F I + V S S+ + PS
Sbjct: 694 TNDNQYVNVTSPSTENYVVSNLMPFTNYEFFVIPYHSGVHSIHGAPSNSMDVLTAEAPPS 753
Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
P + IRM+ + SW P+ DG L G+ I I + +
Sbjct: 754 LPPEDVRIRMLNLTTLRISWKAPKADGINGILKGFQIVIVGQAPNNNRNI-TTNERAASV 812
Query: 2027 NIRDLSENHTYMIRIYARNEIGL 2049
+ L TY IR+ AR+ G+
Sbjct: 813 TLFHLVTGMTYKIRVAARSNGGV 835
Score = 65.3 bits (152), Expect = 5e-10
Identities = 107/496 (21%), Positives = 183/496 (36%), Gaps = 43/496 (8%)
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI-----QFSNHIQLTIDGK 1159
L P II + V++G+ AT A + W+KDG + Q ++H + G
Sbjct: 29 LAPVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGS 88
Query: 1160 KQKLKI---YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD--- 1213
LK+ + DAG Y C N + E S+ + +F + P
Sbjct: 89 LFLLKVNSGKNGKDSDAGAYYCVASNEH--GEVKSNEGSLKLAMLREDFRVRPRTVQALG 146
Query: 1214 ---AYLTVEIPDETLD--VTWYK--KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
A L P + V+W K K+ I+D ++TL SD LII D Y
Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSD---GNLIIDPVDRSDSGTY 203
Query: 1267 TCV---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV ++ + + ++ V E PK ++ + G+ V PQP W
Sbjct: 204 QCVANNMVGERVSNPARLSVFE-KPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITW-- 260
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
+ + T+ I + L I++V+ +D G Y N G + ++ + PS
Sbjct: 261 -KRKNEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSF 319
Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE--YQEIDTTEWISVKNITKTQ---- 1437
KP + + E G + Y+ + Q++ ++S TK
Sbjct: 320 QTKPADQSVPAG--GTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGT 377
Query: 1438 TSIQNLKTNSSYRFRAYAVNEV--DISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTE 1494
+I+ ++ + +N +S A+ V T + PT+E +N T
Sbjct: 378 LTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLM 437
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
L C G P P ++W RDG + ++ + + Y CIA
Sbjct: 438 VGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIA 497
Query: 1553 FNDHGEVETSCVVGIQ 1568
N+ GE S + ++
Sbjct: 498 KNEDGESTWSASLTVE 513
Score = 64.5 bits (150), Expect = 8e-10
Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 42/350 (12%)
Query: 864 ITWYRNNE-IISPSETITQN---FDGENIELVITNVDS---EIDSGDYKCVASNSAG--K 914
ITWY++ + +I+ E + + D ++ L+ N + D+G Y CVASN G K
Sbjct: 61 ITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVK 120
Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKE--ISG 969
S+ G+ + + + + F + ++ + G+ +LEC W + KE I
Sbjct: 121 SNEGS-LKLAMLREDF-RVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQD 178
Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ-----ETSTMLVVKETIPEFIRKLQ 1024
M + +G D G +C+ + L V E P+F ++ +
Sbjct: 179 MPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARLSVFEK-PKFEQEPK 234
Query: 1025 DFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
D V + + + + + W+R E + + + RG L I D
Sbjct: 235 DMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRG----LRIERVQPSD 290
Query: 1084 EGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139
EGEY C R+ + T E + V+ PP T+ +Q V G ATFE L + W
Sbjct: 291 EGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFW 350
Query: 1140 FKDG-SEIQFSNHIQLTIDGKKQ-----KLKIYDCDLDDAGEYSCEVGNS 1183
K+G ++ F +++ + DG+ + L I + D G Y C NS
Sbjct: 351 SKEGQQDLLFPSYV--SADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNS 398
Score = 62.5 bits (145), Expect = 3e-09
Identities = 60/223 (26%), Positives = 84/223 (37%), Gaps = 30/223 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQ-DFQMYYDDDNVA 566
P F K + P G T FEC + G P P W + Q ++ PS
Sbjct: 317 PSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTG 376
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
TL I EV D G + C N+AG + S L V
Sbjct: 377 TLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKV-------------------TTKAVTG 417
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIE 685
+ PPT + Q + GS +L C+ P P I+WL G I + D IS
Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHST 477
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
+H I ++KK G YT +A N +GE++ L ++
Sbjct: 478 GSLH-------IADLKKPDTGVYTCIAKNEDGESTWSASLTVE 513
Score = 61.7 bits (143), Expect = 6e-09
Identities = 101/466 (21%), Positives = 181/466 (38%), Gaps = 60/466 (12%)
Query: 1047 VVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-----SCTAEV 1100
V W +D + ++ + +Y G+ L I D G Y C+ + S A +
Sbjct: 165 VSWRKDDKELRIQDMPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARL 221
Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDG 1158
+V E P+ ++ V+ G F+ +T GD + W + + + + I
Sbjct: 222 SVFE-KPKFEQEPKDMTVDVGAAVLFDCRVT-GDPQPQITWKRKNEPMPVT---RAYIAK 276
Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
+ L+I D GEY C G + +A L V+ P +F + P VPA A
Sbjct: 277 DNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPP-SFQTK-PADQSVPAGGTA 334
Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR-----TLIIRKCTEDDQCEYTCV 1269
+ + ++ K+ + + +D + + TL I + + D+ Y C
Sbjct: 335 TFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCA 394
Query: 1270 LLDA------KSTTKLKVEVV------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+++ K+ K+ + V + PP I + + GS L P P
Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
W+ + I T I S SL I ++ D G+Y +N G + ++T
Sbjct: 455 GISWLRDGLPIDI---TDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLT 511
Query: 1377 ILDK---------------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
+ D PS P +P I+ + + + + W+ P +G I Y+++Y
Sbjct: 512 VEDHTSNAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTSGAGPITGYIIQYYS 571
Query: 1422 IDTTE-WISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
D + W ++ + + T+ I+ LK + SY F A NE I S
Sbjct: 572 PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPS 617
Score = 61.7 bits (143), Expect = 6e-09
Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 20/135 (14%)
Query: 476 DENNYTQYLQKKLNEKID---KLPVFEKPTSEEQSMAPIFVEKLRPKH-TPD-GSTVQFE 530
D Y + E++ +L VFEKP E++ PK T D G+ V F+
Sbjct: 199 DSGTYQCVANNMVGERVSNPARLSVFEKPKFEQE-----------PKDMTVDVGAAVLFD 247
Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
C+V G P+PQITW R+ +P + Y DN L I V P D G + C A+N AG
Sbjct: 248 CRVTGDPQPQITWKRKN---EPMPVTRAYIAKDN-RGLRIERVQPSDEGEYVCYARNPAG 303
Query: 591 FASSTTELIVEAPLS 605
++ L V+AP S
Sbjct: 304 TLEASAHLRVQAPPS 318
Score = 54.8 bits (126), Expect = 6e-07
Identities = 84/403 (20%), Positives = 142/403 (35%), Gaps = 42/403 (10%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK----RGHIR 1072
P I D V A L TA + W +DG+ + K + + + G +
Sbjct: 31 PVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90
Query: 1073 KLYI---RNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124
L + +N D G Y C+ +E S + + L + R + + G A
Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMA 150
Query: 1125 TFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
E +G + +V W KD E++ + + T+ L I D D+G Y C N
Sbjct: 151 VLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLH-SDGNLIIDPVDRSDSGTYQCVANN 209
Query: 1183 ------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSV 1235
S + E+P + P+ + V + D +TW +K
Sbjct: 210 MVGERVSNPARLSVFEKPKFE---QEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP 266
Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYE 1294
+ T + + D R L I + D+ EY C + T + + V+ PP
Sbjct: 267 MPVTRAY-IAKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKP 323
Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEW-------IVNSKIIKKCKHTKPSIDSKSASLTI 1347
+ + G T P P W ++ + TK S + +LTI
Sbjct: 324 ADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKV---SPTGTLTI 380
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKP 1387
++V D G Y N+ G + + + + K + P KP
Sbjct: 381 EEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKP 423
Score = 36.7 bits (81), Expect = 0.18
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 524 GSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGT 580
G EC G+P P ++W + ++ QD Y + D N L+I V D+GT
Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELR-IQDMPRYTLHSDGN---LIIDPVDRSDSGT 202
Query: 581 FTCVAKNAAG 590
+ CVA N G
Sbjct: 203 YQCVANNMVG 212
>AF041053-1|AAC38848.1| 1273|Caenorhabditis elegans SAX-3 protein.
Length = 1273
Score = 99.5 bits (237), Expect = 2e-20
Identities = 100/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)
Query: 636 FSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
F +P+ G +LEC PEP ++W +E+ + + SD ++
Sbjct: 135 FRVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI--- 191
Query: 695 LKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
I V + GTY VA N GE S P L + E P+ + K M V G +V+
Sbjct: 192 --IDPVDRSDSGTYQCVANNMVGERVSNPARLSVF----EKPKFEQEPKDMTVDVGAAVL 245
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
+V G+P+P ITW + N+P+ D + I + + DEG Y A N G
Sbjct: 246 FDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIERVQP-SDEGEYVCYARNPAGT 304
Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNE 871
E SA + V+ PP F + + +V GT + P P+ W + +
Sbjct: 305 LEASAHLRVQ-------APPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQD 357
Query: 872 IISPSETITQNFDGENIELVITNVD-SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT- 929
++ PS + +T + ++D G Y C NSAG S A + + + VT
Sbjct: 358 LLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTG 417
Query: 930 --------FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG 979
++H ++ G + IL CQ S T W + I D R I +
Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSR--ISQH 475
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
D GV CI K+++ + T+ + Q
Sbjct: 476 STGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQ 520
Score = 93.1 bits (221), Expect = 2e-18
Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 28/303 (9%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F ++PK VD G+ +L +CR+ P+P I W K E +P +A ++
Sbjct: 227 PKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP-MPVTRAYIAKDN------R 279
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
L+I V+ EG Y A N G L+++ PP V G +
Sbjct: 280 GLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQA----PPSFQTKPADQSVPAGGTAT 335
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPT--KSDG-----DTHSITILKPKKVKDEGVYTLK 806
+VG P P W K + P+ +DG T ++TI + ++V DEG Y
Sbjct: 336 FECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQV-DEGAYVCA 394
Query: 807 AENSEG--IAETSAVITVEEPTEEN-AEPPLFINR-FQEITVKEKGTIKLVARVTRNPVP 862
NS G +++ + +T + T A+PP I Q T+ + L + + P P
Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454
Query: 863 SITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
I+W R+ I +++ I+Q+ G L I ++ + D+G Y C+A N G+S+ A +
Sbjct: 455 GISWLRDGLPIDITDSRISQHSTG---SLHIADL-KKPDTGVYTCIAKNEDGESTWSASL 510
Query: 922 TID 924
T++
Sbjct: 511 TVE 513
Score = 93.1 bits (221), Expect = 2e-18
Identities = 66/207 (31%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PP+F KP Q V G EC LV P P W +G++ + + A
Sbjct: 316 PPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPT 375
Query: 693 SVLKITNVKKFQEGTYTVVAVNREG----EASLPIVLKIKTGE---KEPPQVIEPLKSMI 745
L I V++ EG Y +N G +A+L + K TG K PP + ++
Sbjct: 376 GTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQT 435
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804
+ G S IL Q G P P I+W ++ P+ ++ S T S+ I KK D GVYT
Sbjct: 436 LMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKK-PDTGVYT 494
Query: 805 LKAENSEGIAETSAVITVEEPTEENAE 831
A+N +G + SA +TVE+ T NA+
Sbjct: 495 CIAKNEDGESTWSASLTVEDHT-SNAQ 520
Score = 78.6 bits (185), Expect = 5e-14
Identities = 126/603 (20%), Positives = 223/603 (36%), Gaps = 62/603 (10%)
Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTEKFT---LISDVKKRTLII--- 1255
P ++V + A L T +TWYK + VI + E+ ++ D L+
Sbjct: 37 PIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNS 96
Query: 1256 -RKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR--GSDVTLLV--D 1310
+ + D Y CV + K ++ D+ R + G ++ +L
Sbjct: 97 GKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMAVLECSP 156
Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH-A 1369
+ FP+P W + K ++ + ++ S +L I V+ +D+G Y+ N G
Sbjct: 157 PRGFPEPVVSWRKDDKELRIQDMPRYTLHS-DGNLIIDPVDRSDSGTYQCVANNMVGERV 215
Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
+++ +KP +P + +D + + +D I + + + + T
Sbjct: 216 SNPARLSVFEKPKFEQEPKDMTVDVGAA-VLFDCRVTGDPQPQITWKRKNEPMPVTRAYI 274
Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
K+ I+ ++ + + YA N +AS + +V Q+ ++ +
Sbjct: 275 AKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASA---HLRVQAPPSFQTKPADQSVP 329
Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK--LKTAKATYENRXXXXXXXXXXXXXX- 1546
T E C G P P W ++G++ L + + + R
Sbjct: 330 AGGTATFE-----CTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVR 384
Query: 1547 -----XYKCIAFNDHG--------EVETSCVVG-IQQKPVITISNEDIKQKHKVGDEWLV 1592
Y C N G +V T V G KP TI + Q VG ++
Sbjct: 385 QVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAIL 444
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
G P P + W ++G L D + ++ T + I +LK+ + YT A N G
Sbjct: 445 PCQASGKPTPGISWLRDG--LPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDG 502
Query: 1653 TSSVEVTLKVYDK---------------PSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
S+ +L V D PS P P+I+ ++ V + W P G
Sbjct: 503 ESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIV-NVTDTEVELHWNAPSTSGAGP 561
Query: 1698 LTKYAIEKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
+T Y I+ + PD W + D E Y I+ L + YMF + A+N G S
Sbjct: 562 ITGYIIQYYSPDLGQTWFNIPDYVASTE-YRIKGLKPSHSYMFVIRAENEKGIGTPSVSS 620
Query: 1757 PIV 1759
+V
Sbjct: 621 ALV 623
Score = 72.5 bits (170), Expect = 3e-12
Identities = 135/617 (21%), Positives = 231/617 (37%), Gaps = 82/617 (13%)
Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542
+E P+ ++ L C G P K+TWY+DG+ + T K +
Sbjct: 34 IEHPI-DVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90
Query: 1543 ------------XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK----V 1586
Y C+A N+HGEV+++ + + + ED + + + +
Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSN-----EGSLKLAMLREDFRVRPRTVQAL 145
Query: 1587 GDEWLVTAVI--EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
G E V G P P V W K+ +L T ++I I + RS S Y
Sbjct: 146 GGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI-IDPVDRSDSGTYQ 204
Query: 1645 IEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
A+N G S L V++KP + P M +V + + D K
Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWK--- 261
Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA-----LESEPI 1758
K+EP +A +R + +Q +E EY+ A+NP G EA +++ P
Sbjct: 262 RKNEPMPVTRAYIAKDNRGLRIERVQPSDEG-EYV--CYARNPAGTLEASAHLRVQAPPS 318
Query: 1759 VIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
D VP+ + S W K G ++ + + +G+ K
Sbjct: 319 FQTKPADQSVPAGGTATFECTLVGQPSPAYFW---SKEGQQDLL-FPSYVSADGRT-KVS 373
Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
++++ + N G+SL + T T P++P +
Sbjct: 374 PTGTLTIEEVRQVDEGA---YVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHG 430
Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK----IVTVGGSVHEHC-----I 1927
++++ + G S I K G SW + I + +H I
Sbjct: 431 HQNQTLMV--------GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHI 482
Query: 1928 ENIKEKDEIIFRISAENTVG-----VSLPTE-----SQSVRLEKHATVPSPPTAPLEIRM 1977
++K+ D ++ A+N G SL E +Q VR+ + PS PT P+ + +
Sbjct: 483 ADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIVNV 542
Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
+ + + W P G P+ GY I D+ +T W + +T ++ I+ L +H
Sbjct: 543 TDTEVEL-HWNAPSTSGAGPITGYIIQYYSPDLGQT-WFNIPDYVAST-EYRIKGLKPSH 599
Query: 2036 TYMIRIYARNEIGLSEP 2052
+YM I A NE G+ P
Sbjct: 600 SYMFVIRAENEKGIGTP 616
Score = 68.9 bits (161), Expect = 4e-11
Identities = 134/623 (21%), Positives = 222/623 (35%), Gaps = 65/623 (10%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXX 1538
+ P E+ K++T + + C G PQP++TW R + + +A ++
Sbjct: 225 EKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIE 284
Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
Y C A N G +E S + +Q P D Q G + G
Sbjct: 285 RVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPAD--QSVPAGGTATFECTLVG 342
Query: 1599 IPPPEVIWYKNGNKLENDKEY----NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
P P W K G + Y T T + I+E+++ Y N+AG+S
Sbjct: 343 QPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSS 402
Query: 1655 SVEVTLKVYDK------PSKPEGPVIMREISRESVTI----------EWKPP-----LDD 1693
+ LKV K P+KP P I +++ + KP L D
Sbjct: 403 LSKAALKVTTKAVTGNTPAKPP-PTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRD 461
Query: 1694 G-GLELTKYAIEKHEPDNNRWIKVADVDR-DVETY-CIQKLNENCEYMFRVIAQNPVGFS 1750
G +++T I +H + + +AD+ + D Y CI K NE+ E + S
Sbjct: 462 GLPIDITDSRISQHSTGS---LHIADLKKPDTGVYTCIAK-NEDGESTWSASLTVEDHTS 517
Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE- 1809
A + + + + PS D E V + W +G PI Y ++
Sbjct: 518 NA---QFVRMPDPSNFPSSPTQPIIVNVTDTE-VELHWNAPSTSGAGPITGYIIQYYSPD 573
Query: 1810 -GKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-----T 1862
G+ W RI+ L + +Y F I A NE G P S +T K
Sbjct: 574 LGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPSVSSALVTTSKPAAQVA 633
Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP-------------ITNYIIEFKTVKG 1909
L+ ++ + + + +K E ++ + I Y I+++
Sbjct: 634 LSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAVRLFWKKRKLEELIDGYYIKWRGPPR 693
Query: 1910 KSWTKIVTV-GGSVHEHCIENIKE-KDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
+ + V V S + + N+ + F I + V S S+ + PS
Sbjct: 694 TNDNQYVNVTSPSTENYVVSNLMPFTNYEFFVIPYHSGVHSIHGAPSNSMDVLTAEAPPS 753
Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
P + IRM+ + SW P+ DG L G+ I I + +
Sbjct: 754 LPPEDVRIRMLNLTTLRISWKAPKADGINGILKGFQIVIVGQAPNNNRNI-TTNERAASV 812
Query: 2027 NIRDLSENHTYMIRIYARNEIGL 2049
+ L TY IR+ AR+ G+
Sbjct: 813 TLFHLVTGMTYKIRVAARSNGGV 835
Score = 65.3 bits (152), Expect = 5e-10
Identities = 107/496 (21%), Positives = 183/496 (36%), Gaps = 43/496 (8%)
Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI-----QFSNHIQLTIDGK 1159
L P II + V++G+ AT A + W+KDG + Q ++H + G
Sbjct: 29 LAPVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGS 88
Query: 1160 KQKLKI---YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD--- 1213
LK+ + DAG Y C N + E S+ + +F + P
Sbjct: 89 LFLLKVNSGKNGKDSDAGAYYCVASNEH--GEVKSNEGSLKLAMLREDFRVRPRTVQALG 146
Query: 1214 ---AYLTVEIPDETLD--VTWYK--KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
A L P + V+W K K+ I+D ++TL SD LII D Y
Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSD---GNLIIDPVDRSDSGTY 203
Query: 1267 TCV---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
CV ++ + + ++ V E PK ++ + G+ V PQP W
Sbjct: 204 QCVANNMVGERVSNPARLSVFE-KPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITW-- 260
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
+ + T+ I + L I++V+ +D G Y N G + ++ + PS
Sbjct: 261 -KRKNEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSF 319
Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE--YQEIDTTEWISVKNITKTQ---- 1437
KP + + E G + Y+ + Q++ ++S TK
Sbjct: 320 QTKPADQSVPAG--GTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGT 377
Query: 1438 TSIQNLKTNSSYRFRAYAVNEV--DISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTE 1494
+I+ ++ + +N +S A+ V T + PT+E +N T
Sbjct: 378 LTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLM 437
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
L C G P P ++W RDG + ++ + + Y CIA
Sbjct: 438 VGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIA 497
Query: 1553 FNDHGEVETSCVVGIQ 1568
N+ GE S + ++
Sbjct: 498 KNEDGESTWSASLTVE 513
Score = 64.5 bits (150), Expect = 8e-10
Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 42/350 (12%)
Query: 864 ITWYRNNE-IISPSETITQN---FDGENIELVITNVDS---EIDSGDYKCVASNSAG--K 914
ITWY++ + +I+ E + + D ++ L+ N + D+G Y CVASN G K
Sbjct: 61 ITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVK 120
Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKE--ISG 969
S+ G+ + + + + F + ++ + G+ +LEC W + KE I
Sbjct: 121 SNEGS-LKLAMLREDF-RVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQD 178
Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ-----ETSTMLVVKETIPEFIRKLQ 1024
M + +G D G +C+ + L V E P+F ++ +
Sbjct: 179 MPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARLSVFEK-PKFEQEPK 234
Query: 1025 DFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
D V + + + + + W+R E + + + RG L I D
Sbjct: 235 DMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRG----LRIERVQPSD 290
Query: 1084 EGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139
EGEY C R+ + T E + V+ PP T+ +Q V G ATFE L + W
Sbjct: 291 EGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFW 350
Query: 1140 FKDG-SEIQFSNHIQLTIDGKKQ-----KLKIYDCDLDDAGEYSCEVGNS 1183
K+G ++ F +++ + DG+ + L I + D G Y C NS
Sbjct: 351 SKEGQQDLLFPSYV--SADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNS 398
Score = 62.5 bits (145), Expect = 3e-09
Identities = 60/223 (26%), Positives = 84/223 (37%), Gaps = 30/223 (13%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQ-DFQMYYDDDNVA 566
P F K + P G T FEC + G P P W + Q ++ PS
Sbjct: 317 PSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTG 376
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
TL I EV D G + C N+AG + S L V
Sbjct: 377 TLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKV-------------------TTKAVTG 417
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIE 685
+ PPT + Q + GS +L C+ P P I+WL G I + D IS
Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHST 477
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
+H I ++KK G YT +A N +GE++ L ++
Sbjct: 478 GSLH-------IADLKKPDTGVYTCIAKNEDGESTWSASLTVE 513
Score = 61.7 bits (143), Expect = 6e-09
Identities = 101/466 (21%), Positives = 181/466 (38%), Gaps = 60/466 (12%)
Query: 1047 VVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-----SCTAEV 1100
V W +D + ++ + +Y G+ L I D G Y C+ + S A +
Sbjct: 165 VSWRKDDKELRIQDMPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARL 221
Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDG 1158
+V E P+ ++ V+ G F+ +T GD + W + + + + I
Sbjct: 222 SVFE-KPKFEQEPKDMTVDVGAAVLFDCRVT-GDPQPQITWKRKNEPMPVT---RAYIAK 276
Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
+ L+I D GEY C G + +A L V+ P +F + P VPA A
Sbjct: 277 DNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPP-SFQTK-PADQSVPAGGTA 334
Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR-----TLIIRKCTEDDQCEYTCV 1269
+ + ++ K+ + + +D + + TL I + + D+ Y C
Sbjct: 335 TFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCA 394
Query: 1270 LLDA------KSTTKLKVEVV------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+++ K+ K+ + V + PP I + + GS L P P
Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
W+ + I T I S SL I ++ D G+Y +N G + ++T
Sbjct: 455 GISWLRDGLPIDI---TDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLT 511
Query: 1377 ILDK---------------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
+ D PS P +P I+ + + + + W+ P +G I Y+++Y
Sbjct: 512 VEDHTSNAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTSGAGPITGYIIQYYS 571
Query: 1422 IDTTE-WISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
D + W ++ + + T+ I+ LK + SY F A NE I S
Sbjct: 572 PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPS 617
Score = 61.7 bits (143), Expect = 6e-09
Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 20/135 (14%)
Query: 476 DENNYTQYLQKKLNEKID---KLPVFEKPTSEEQSMAPIFVEKLRPKH-TPD-GSTVQFE 530
D Y + E++ +L VFEKP E++ PK T D G+ V F+
Sbjct: 199 DSGTYQCVANNMVGERVSNPARLSVFEKPKFEQE-----------PKDMTVDVGAAVLFD 247
Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
C+V G P+PQITW R+ +P + Y DN L I V P D G + C A+N AG
Sbjct: 248 CRVTGDPQPQITWKRKN---EPMPVTRAYIAKDN-RGLRIERVQPSDEGEYVCYARNPAG 303
Query: 591 FASSTTELIVEAPLS 605
++ L V+AP S
Sbjct: 304 TLEASAHLRVQAPPS 318
Score = 54.8 bits (126), Expect = 6e-07
Identities = 84/403 (20%), Positives = 142/403 (35%), Gaps = 42/403 (10%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK----RGHIR 1072
P I D V A L TA + W +DG+ + K + + + G +
Sbjct: 31 PVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90
Query: 1073 KLYI---RNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124
L + +N D G Y C+ +E S + + L + R + + G A
Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMA 150
Query: 1125 TFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
E +G + +V W KD E++ + + T+ L I D D+G Y C N
Sbjct: 151 VLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLH-SDGNLIIDPVDRSDSGTYQCVANN 209
Query: 1183 ------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSV 1235
S + E+P + P+ + V + D +TW +K
Sbjct: 210 MVGERVSNPARLSVFEKPKFE---QEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP 266
Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYE 1294
+ T + + D R L I + D+ EY C + T + + V+ PP
Sbjct: 267 MPVTRAY-IAKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKP 323
Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEW-------IVNSKIIKKCKHTKPSIDSKSASLTI 1347
+ + G T P P W ++ + TK S + +LTI
Sbjct: 324 ADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKV---SPTGTLTI 380
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKP 1387
++V D G Y N+ G + + + + K + P KP
Sbjct: 381 EEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKP 423
Score = 36.7 bits (81), Expect = 0.18
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 524 GSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGT 580
G EC G+P P ++W + ++ QD Y + D N L+I V D+GT
Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELR-IQDMPRYTLHSDGN---LIIDPVDRSDSGT 202
Query: 581 FTCVAKNAAG 590
+ CVA N G
Sbjct: 203 YQCVANNMVG 212
>AY724774-1|AAU21474.1| 750|Caenorhabditis elegans UNC-89-B
protein.
Length = 750
Score = 97.9 bits (233), Expect = 7e-20
Identities = 91/332 (27%), Positives = 132/332 (39%), Gaps = 27/332 (8%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F L + G +V FEC G P P I W + + + +M D L
Sbjct: 3 APGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRL 62
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
++ +V G F CVA N G AS+ EL++E + T+
Sbjct: 63 ILSDVTFLSEGYFRCVATNEHGTASTKAELVIE-------GDRTIGSRPLPEVNGEP--- 112
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
E P + + EG+ + + IP P + W G+EIV D +
Sbjct: 113 -EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 171
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG----EASLPIV-------LKIKTGEKEPPQV 737
L I N EG Y++ A N+ G E SL I+ + G PP
Sbjct: 172 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGF 231
Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKS-DGDTHSITILK 793
+ LK+ V I VVG+P P + W N K P + +S G +H++ IL
Sbjct: 232 VRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL- 290
Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
++D G Y A+NS G A +SAV+ V P
Sbjct: 291 DTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 322
Score = 89.8 bits (213), Expect = 2e-17
Identities = 86/333 (25%), Positives = 136/333 (40%), Gaps = 36/333 (10%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G P F+ + G + EC P P I WL G E+ DE I + +D
Sbjct: 1 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAAD--- 57
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGEKE--PP 735
L +++V EG + VA N G AS L I+ GE E P
Sbjct: 58 GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKP 117
Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKSDGDTHS 788
++ L +M + +G V + G P PT+ W K+ + + K + + H
Sbjct: 118 RIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHH 177
Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPLFINRFQ 840
+ I+ DEG Y+L+A N G A+T + + P +A+ PP F+ + +
Sbjct: 178 LVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 236
Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEI 899
V V +P P + W+ N + I P I Q+ G + L+I + E
Sbjct: 237 NKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLE- 295
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
D+G+Y A NS G +S A + + V + +K
Sbjct: 296 DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 328
Score = 70.9 bits (166), Expect = 9e-12
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
+Y E + + + P+PDI W F+G +I S + L IT K
Sbjct: 498 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 557
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
G Y A N G+A I++ + T P I+PL + + + + +V G P
Sbjct: 558 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 613
Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
P + W K +P+ + DG I+ +D G+Y+ A N G A TS
Sbjct: 614 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 673
Query: 820 ITVEEPTEEN 829
+TVE + N
Sbjct: 674 VTVEAEGDYN 683
Score = 61.3 bits (142), Expect = 7e-09
Identities = 33/97 (34%), Positives = 47/97 (48%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P FV +L+ KH + F+C V G+P P++ WF I P ++ L+
Sbjct: 229 PGFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALI 288
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606
I + EDAG + AKN+ G ASS+ L V P D
Sbjct: 289 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVPFLD 325
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
++P PL +P + + C+ G P P + W +DG +L + +A +
Sbjct: 2 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 61
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
++C+A N+HG T +G + P + E+ K + +
Sbjct: 62 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 121
Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
G E V +I GIP P V WYK+G ++ D K T + + I
Sbjct: 122 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 181
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+Y++EA+N G++ E +L +
Sbjct: 182 NASPDDEGEYSLEATNKLGSAKTEGSLNI 210
Score = 53.6 bits (123), Expect = 1e-06
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
+ +++ + V G P P I W + P + G + + + ++ G
Sbjct: 502 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 561
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
Y A+N G A+ + I V+ T N PL +N+ T +++ RV P
Sbjct: 562 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 614
Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
P + W + I S I DG + +I N DSG Y CVA N AG+++ V
Sbjct: 615 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 674
Query: 922 TIDVE 926
T++ E
Sbjct: 675 TVEAE 679
Score = 53.2 bits (122), Expect = 2e-06
Identities = 26/93 (27%), Positives = 49/93 (52%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+
Sbjct: 586 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 645
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
I + D+G ++CVA N AG A+++ + VEA
Sbjct: 646 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 678
Score = 48.0 bits (109), Expect = 7e-05
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
+E P R L + + E +V + V T V W +DG+ I P + F
Sbjct: 113 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 172
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
I L I N S DEGEYS ++ +A+ + ++ PP +
Sbjct: 173 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 232
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
+L+N+ V F+ + A V WF +G +I I++ + G L I D
Sbjct: 233 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 292
Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
L+DAGEY G++ +A+L V P ++ E + P T+ Y
Sbjct: 293 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 343
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437
P+PP + P I E+ + + W + + YV+E +E+ +W ++ NI +
Sbjct: 354 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 413
Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
++NL+ SY+FR A N ISD S
Sbjct: 414 CKVRNLELGKSYQFRVRAENIYGISDPS 441
Score = 39.9 bits (89), Expect = 0.019
Identities = 45/203 (22%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXX 1534
P + + L N++ +E+ G+P P V WY+DG+++ K T E
Sbjct: 117 PRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIH 176
Query: 1535 XXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE------------DIK 1581
Y A N G +T + I + I ++E +K
Sbjct: 177 HLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLK 236
Query: 1582 QKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSH 1639
KH + ++ G P PEV W+ NG K+ I + S + I +
Sbjct: 237 NKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLED 296
Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
+ +Y A N+ G++S L V
Sbjct: 297 AGEYVATAKNSHGSASSSAVLDV 319
Score = 39.1 bits (87), Expect = 0.034
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++
Sbjct: 481 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 540
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
Y + TL I E+ G + C AKN G A
Sbjct: 541 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 574
Score = 37.9 bits (84), Expect = 0.078
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
NP PSI W ++ + E I + + +I + + + G ++CVA+N G +S
Sbjct: 30 NPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTK 89
Query: 919 ARVTIDVEKVTFVKHL-QKSYETEEGK 944
A + I+ ++ + L + + E EE K
Sbjct: 90 AELVIEGDRTIGSRPLPEVNGEPEECK 116
Score = 35.9 bits (79), Expect = 0.32
Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 11/130 (8%)
Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDD----KITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
L + + I EI + PY +++ K+ TPP R + E T +TL
Sbjct: 317 LDVTVPFLDSIKFNGEIDVT-PYLTEEYGFKKLNTASLPTPPD--RGPFIKEVTGHYLTL 373
Query: 1885 KWTEPE-SNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA 1942
W + + P Y+IE + + K W+ + + V + + N++ FR+ A
Sbjct: 374 SWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCK--VRNLELGKSYQFRVRA 431
Query: 1943 ENTVGVSLPT 1952
EN G+S P+
Sbjct: 432 ENIYGISDPS 441
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1786 ITWFPSEKNGGS-PIIDYKVEIKQ-EGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYAR 1842
++W P+++ P + Y +EI++ K+W +++ L + +YQFR+ A
Sbjct: 373 LSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAE 432
Query: 1843 NEIGTSLP 1850
N G S P
Sbjct: 433 NIYGISDP 440
>Z49938-4|CAA90189.3| 2180|Caenorhabditis elegans Hypothetical protein
C09D8.1a protein.
Length = 2180
Score = 96.3 bits (229), Expect = 2e-19
Identities = 117/527 (22%), Positives = 203/527 (38%), Gaps = 39/527 (7%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKATYENRXXX 1535
P +E + E + ++C G P+ KV W RD L + + +T N
Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCV---VGIQQKPVITISNEDIKQKHKVGDEWLV 1592
Y+CIA N G + V +++ P + + VG +
Sbjct: 211 MIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINL 270
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
T V G P P V W K + +D T +V+ + ++ + + +T A + G
Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPS---TAPIGKNVLTLTHVESTEN--FTCVAVSALG 325
Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE--LTKYAIEKHEPDN 1710
T+ + P P +++ ++ ESV I WKPP + + + Y ++ E +
Sbjct: 326 NIEATTTVIAKELPPPPVN-IVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGRS 384
Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
+R + ++ + I L Y F V + PVG LES P+ +T P+
Sbjct: 385 SRGKTMETLENSL---VIDGLVAFQTYEFTVRSAGPVGV--GLESLPVEAQTKPSKPATA 439
Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-----IKQEGKKWK-XXXXXXXXXA 1824
++ +S+ + W P E+ G I YKV + ++WK
Sbjct: 440 PVSPQARSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMT 498
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
I L ++ Y R+ A+N G S P ++ +T+ P QP V SR + L
Sbjct: 499 TINGLEPDSRYFVRVIAQNSEGDS-PLST--LVTVATRQGIPGQPPMLTVKALDSRRMQL 555
Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
W +P + SP+ Y + + T G+ K +T+ +H + + FR++A +
Sbjct: 556 TWDKPLYS--SPVVGYTVRYNTSDGE---KELTLTSPHEKHVVTGLHPDKYYYFRVAAYS 610
Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
G TE + A++P + S V W PE
Sbjct: 611 DRGQGEFTEPMISK--TIASIPLSSPTIVSAAATSSKSVEIRWKGPE 655
Score = 66.9 bits (156), Expect = 1e-10
Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 36/301 (11%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E P +P + V + S I CR P P + W G+ I IS+ +
Sbjct: 44 EDDPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISI---KSLA 100
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV----LKIKTGEKEP---PQV-IEP- 740
S L+ V + TVV+ + + + P+V L + +K P PQ+ + P
Sbjct: 101 TGLSTLRFERVS--LDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPS 158
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP------ 794
LKS V QG++ +S +V G+PR + W ++ P L ++DG TI P
Sbjct: 159 LKS--VEQGKTAYVSCRVRGDPRAKVLWLRDLIP---LDIRADGRYSVSTIGNPGALMIQ 213
Query: 795 -KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKL 852
+ +D+G Y A N+ G+A + A + PP F + + + V G I L
Sbjct: 214 HAREEDQGKYECIARNTLGVAHSKAANLY---VKVRRVPPYFSYKLERQYVVGVGGNINL 270
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
P+P + W + + ++ + G+N+ L +T+V+S + ++ CVA ++
Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPSTAP--IGKNV-LTLTHVES---TENFTCVAVSAL 324
Query: 913 G 913
G
Sbjct: 325 G 325
Score = 64.5 bits (150), Expect = 8e-10
Identities = 206/967 (21%), Positives = 345/967 (35%), Gaps = 115/967 (11%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQL-TIDGKKQK 1162
P ++ R + V +K +F G+ L V W +G I N I + ++
Sbjct: 47 PARLVVRPDSSTVVDESKISFFCR-ADGNPLPSVIWRVNGKSITDHNRISIKSLATGLST 105
Query: 1163 LKIYDCDLDD-AGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPA------N 1211
L+ LDD A SC N ++ P + P+ L P+
Sbjct: 106 LRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQG 165
Query: 1212 TDAYLTVEIP-DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
AY++ + D V W + ++ ++++ + L+I+ E+DQ +Y C
Sbjct: 166 KTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYEC 225
Query: 1269 VLLDA-----KSTTKLKVEVVEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
+ + L V+V PP ER+Y + G ++ L +P P W
Sbjct: 226 IARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWK 285
Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
++ T P K+ LT+ VE+T+ + + G+ + V + P
Sbjct: 286 KTDLMVLDDPSTAPI--GKNV-LTLTHVESTEN--FTCVAVSALGNIEATTTVIAKELPP 340
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
PP + + S S+ I W P+ N I YVV Y+ + +E S + KT +++N
Sbjct: 341 PPVNIVVSSVTSESVVITWKPPKY--NEAINKYVVNYR-LKYSEGRSSRG--KTMETLEN 395
Query: 1443 -LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
L + F+ Y E V +TK P P+ N D +
Sbjct: 396 SLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPAT-APVSPQARSLNRD-SI 453
Query: 1502 TCIFGGVPQPK--VTWYR---DGKKLKTAKATYENRXXXXXXXXXX------XXXXXYKC 1550
+G QP +T Y+ + T ++ +
Sbjct: 454 LVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRV 513
Query: 1551 IAFNDHGEVETSCVVGIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
IA N G+ S +V + Q P++T+ D ++ D+ L ++ + G
Sbjct: 514 IAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGY---- 569
Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK-V 1662
+ Y N + +KE +T+ + V+ + + + + G + + K +
Sbjct: 570 TVRY---NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTI 626
Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPP-------------LDDGGLELTKYA-IEKHEP 1708
P V S +SV I WK P ++ LE +K A +E E
Sbjct: 627 ASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEY 686
Query: 1709 DNNRWIKVADVDR-------DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
D + + +DR D +Y + L Y V A G+ ES V+K
Sbjct: 687 DEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGP--ESSIRVVK 744
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNGG----SPIIDYKVE---IKQEGKKW 1813
T DVPS SV +TW P+ NG +D V + ++G K
Sbjct: 745 TLEDVPSAPRNFNAELT-SATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKK 803
Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
+ + L NT Y FR+ A N G IT G PP P
Sbjct: 804 RIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQG---IPPEAPE- 859
Query: 1872 FVVSESTSRS-----VTLKWTEPESN-GGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHE 1924
+VS S R ++W P+ +PI Y + + S+ K TV G+
Sbjct: 860 -IVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLS 918
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM-VGSNIV 1983
I + ++AEN G SQ+ V SP P++++ V +
Sbjct: 919 TTISGLWMGVVYDVLLAAENREG-----RSQNATETIATPVGSPDGEPIDVQYEVMKGKI 973
Query: 1984 MTSWGTP 1990
+ SW P
Sbjct: 974 VVSWRPP 980
Score = 61.3 bits (142), Expect = 7e-09
Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 20/205 (9%)
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KTVKGKSWTKIV 1916
I K L PP P N VVS TS SV + W P+ N I Y++ + K +G+S ++
Sbjct: 334 IAKELPPP--PVNIVVSSVTSESVVITWKPPKYN--EAINKYVVNYRLKYSEGRS-SRGK 388
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGV---SLPTESQSVRLEKHATVPSPPTAPL 1973
T+ + I+ + F + + VGV SLP E+Q+ + K AT P P A
Sbjct: 389 TMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQT-KPSKPATAPVSPQA-- 445
Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNTLKF--NIRD 2030
R + + ++ WG E G + GY + D+ T E + D + +F I
Sbjct: 446 --RSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTING 502
Query: 2031 LSENHTYMIRIYARNEIGLSEPLES 2055
L + Y +R+ A+N G PL +
Sbjct: 503 LEPDSRYFVRVIAQNSEG-DSPLST 526
Score = 60.1 bits (139), Expect = 2e-08
Identities = 100/451 (22%), Positives = 177/451 (39%), Gaps = 53/451 (11%)
Query: 1641 SKYTIE--ASNTAGTSSVEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGL 1696
S+Y + A N+ G S + + V + P P ++ + + + + W PL
Sbjct: 507 SRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSS-- 564
Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
+ Y + + D + + + E + + L+ + Y FRV A + G E +E
Sbjct: 565 PVVGYTVRYNTSDGEKELTLTSPH---EKHVVTGLHPDKYYYFRVAAYSDRGQGEF--TE 619
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVE-IKQEGKKW- 1813
P++ KT +P ++SV I W P +K + Y++ + E K
Sbjct: 620 PMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTA 679
Query: 1814 -----KXXXXXXXXXARIQKLSI-----NTTY---QFRIYARNEI----GTSLPYTSDDK 1856
+ + + ++S+ T+Y Y+ EI T Y +
Sbjct: 680 NLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESS 739
Query: 1857 ITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK----- 1910
I + KTL PS PRNF +++ SV L W P + G+ + Y+ + V G+
Sbjct: 740 IRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEK 799
Query: 1911 -SWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
S +IV + S + ++++ E FR++A N G +E +S+ T P
Sbjct: 800 GSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIP 854
Query: 1969 PTAPLEIRMVGSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVD 2020
P AP EI V + + W P+ P+ YN+ +R +++ VD
Sbjct: 855 PEAP-EIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVD 913
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
L I L Y + + A N G S+
Sbjct: 914 GTDLSTTISGLWMGVVYDVLLAAENREGRSQ 944
Score = 44.0 bits (99), Expect = 0.001
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPED 577
K G T C+V G PR ++ W R + D + N L+I+ ED
Sbjct: 160 KSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREED 219
Query: 578 AGTFTCVAKNAAGFASS 594
G + C+A+N G A S
Sbjct: 220 QGKYECIARNTLGVAHS 236
Score = 38.7 bits (86), Expect = 0.045
Identities = 75/305 (24%), Positives = 109/305 (35%), Gaps = 30/305 (9%)
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGP 1672
D+ + + TS + + +L S + T+ AS G SS+ V + D PS P
Sbjct: 698 DRMSVVVPSDATSYV-LSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRN- 755
Query: 1673 VIMREI-SRESVTIEWKPPLDDGGLELTKYA----IEKHEPDNNRWIKVADV---DRDVE 1724
E+ S SV + W P G L Y + EP + K V D
Sbjct: 756 -FNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKR 814
Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
+ + L+ N EY FR+ A N G E E + I+ T P D V
Sbjct: 815 YFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSII--TQGIPPEAPEIVSVSLDRDEPPV 872
Query: 1785 Y--ITW-FPSEKNGGSPIIDYKVEIKQEG-----KKWKXXXXXXXXXARIQKLSINTTYQ 1836
I W P K +PI Y + ++ +G K K I L + Y
Sbjct: 873 VARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTT-ISGLWMGVVYD 931
Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGS 1895
+ A N G S T +G +P +P + V E + + W P E
Sbjct: 932 VLLAAENREGRSQNATETIATPVG---SPDGEPID-VQYEVMKGKIVVSWRPPSEEKRNG 987
Query: 1896 PITNY 1900
IT+Y
Sbjct: 988 NITSY 992
Score = 37.5 bits (83), Expect = 0.10
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 13/96 (13%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F KL ++ G + C GYP P++ W ++T + M DD + A +
Sbjct: 250 PYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFW-KKTDL--------MVLDDPSTAPI 300
Query: 569 ---VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V+ E FTCVA +A G +TT +I +
Sbjct: 301 GKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAK 336
Score = 36.7 bits (81), Expect = 0.18
Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 31/273 (11%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEG-PV-IMREISRESVTIEWKPPLDD---GGLELT 1699
+ A N G S T + P+G P+ + E+ + + + W+PP ++ G +
Sbjct: 934 LAAENREGRSQ-NATETIATPVGSPDGEPIDVQYEVMKGKIVVSWRPPSEEKRNGNITSY 992
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756
K + + +R+ + T+ ++N Y+F+V A G +S L
Sbjct: 993 KAILSAMDATADRYEQPVPAPSTSSTF---EVNVRRAYLFKVAAATMKGIGPYSPVLTIN 1049
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWK 1814
P AL P N + + W + S ++ Y E + + +KWK
Sbjct: 1050 PD--PAALVGPPTNVRVEATS---NSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWK 1104
Query: 1815 XXXXXXXXX------ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
A + L+ + Y F + A + + D T+ +++TP
Sbjct: 1105 QLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLA---VKNNRQGPCSDPPTVLESVTPTYM 1161
Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
+N V TS SV L W E NG + Y+
Sbjct: 1162 VQNLRVLWKTSNSVQLTW---EYNGPRNVGFYV 1191
>Z46811-1|CAA86842.3| 2180|Caenorhabditis elegans Hypothetical protein
C09D8.1a protein.
Length = 2180
Score = 96.3 bits (229), Expect = 2e-19
Identities = 117/527 (22%), Positives = 203/527 (38%), Gaps = 39/527 (7%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKATYENRXXX 1535
P +E + E + ++C G P+ KV W RD L + + +T N
Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCV---VGIQQKPVITISNEDIKQKHKVGDEWLV 1592
Y+CIA N G + V +++ P + + VG +
Sbjct: 211 MIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINL 270
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
T V G P P V W K + +D T +V+ + ++ + + +T A + G
Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPS---TAPIGKNVLTLTHVESTEN--FTCVAVSALG 325
Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE--LTKYAIEKHEPDN 1710
T+ + P P +++ ++ ESV I WKPP + + + Y ++ E +
Sbjct: 326 NIEATTTVIAKELPPPPVN-IVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGRS 384
Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
+R + ++ + I L Y F V + PVG LES P+ +T P+
Sbjct: 385 SRGKTMETLENSL---VIDGLVAFQTYEFTVRSAGPVGV--GLESLPVEAQTKPSKPATA 439
Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-----IKQEGKKWK-XXXXXXXXXA 1824
++ +S+ + W P E+ G I YKV + ++WK
Sbjct: 440 PVSPQARSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMT 498
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
I L ++ Y R+ A+N G S P ++ +T+ P QP V SR + L
Sbjct: 499 TINGLEPDSRYFVRVIAQNSEGDS-PLST--LVTVATRQGIPGQPPMLTVKALDSRRMQL 555
Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
W +P + SP+ Y + + T G+ K +T+ +H + + FR++A +
Sbjct: 556 TWDKPLYS--SPVVGYTVRYNTSDGE---KELTLTSPHEKHVVTGLHPDKYYYFRVAAYS 610
Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
G TE + A++P + S V W PE
Sbjct: 611 DRGQGEFTEPMISK--TIASIPLSSPTIVSAAATSSKSVEIRWKGPE 655
Score = 66.9 bits (156), Expect = 1e-10
Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 36/301 (11%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E P +P + V + S I CR P P + W G+ I IS+ +
Sbjct: 44 EDDPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISI---KSLA 100
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV----LKIKTGEKEP---PQV-IEP- 740
S L+ V + TVV+ + + + P+V L + +K P PQ+ + P
Sbjct: 101 TGLSTLRFERVS--LDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPS 158
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP------ 794
LKS V QG++ +S +V G+PR + W ++ P L ++DG TI P
Sbjct: 159 LKS--VEQGKTAYVSCRVRGDPRAKVLWLRDLIP---LDIRADGRYSVSTIGNPGALMIQ 213
Query: 795 -KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKL 852
+ +D+G Y A N+ G+A + A + PP F + + + V G I L
Sbjct: 214 HAREEDQGKYECIARNTLGVAHSKAANLY---VKVRRVPPYFSYKLERQYVVGVGGNINL 270
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
P+P + W + + ++ + G+N+ L +T+V+S + ++ CVA ++
Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPSTAP--IGKNV-LTLTHVES---TENFTCVAVSAL 324
Query: 913 G 913
G
Sbjct: 325 G 325
Score = 64.5 bits (150), Expect = 8e-10
Identities = 206/967 (21%), Positives = 345/967 (35%), Gaps = 115/967 (11%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQL-TIDGKKQK 1162
P ++ R + V +K +F G+ L V W +G I N I + ++
Sbjct: 47 PARLVVRPDSSTVVDESKISFFCR-ADGNPLPSVIWRVNGKSITDHNRISIKSLATGLST 105
Query: 1163 LKIYDCDLDD-AGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPA------N 1211
L+ LDD A SC N ++ P + P+ L P+
Sbjct: 106 LRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQG 165
Query: 1212 TDAYLTVEIP-DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
AY++ + D V W + ++ ++++ + L+I+ E+DQ +Y C
Sbjct: 166 KTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYEC 225
Query: 1269 VLLDA-----KSTTKLKVEVVEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
+ + L V+V PP ER+Y + G ++ L +P P W
Sbjct: 226 IARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWK 285
Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
++ T P K+ LT+ VE+T+ + + G+ + V + P
Sbjct: 286 KTDLMVLDDPSTAPI--GKNV-LTLTHVESTEN--FTCVAVSALGNIEATTTVIAKELPP 340
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
PP + + S S+ I W P+ N I YVV Y+ + +E S + KT +++N
Sbjct: 341 PPVNIVVSSVTSESVVITWKPPKY--NEAINKYVVNYR-LKYSEGRSSRG--KTMETLEN 395
Query: 1443 -LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
L + F+ Y E V +TK P P+ N D +
Sbjct: 396 SLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPAT-APVSPQARSLNRD-SI 453
Query: 1502 TCIFGGVPQPK--VTWYR---DGKKLKTAKATYENRXXXXXXXXXX------XXXXXYKC 1550
+G QP +T Y+ + T ++ +
Sbjct: 454 LVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRV 513
Query: 1551 IAFNDHGEVETSCVVGIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
IA N G+ S +V + Q P++T+ D ++ D+ L ++ + G
Sbjct: 514 IAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGY---- 569
Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK-V 1662
+ Y N + +KE +T+ + V+ + + + + G + + K +
Sbjct: 570 TVRY---NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTI 626
Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPP-------------LDDGGLELTKYA-IEKHEP 1708
P V S +SV I WK P ++ LE +K A +E E
Sbjct: 627 ASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEY 686
Query: 1709 DNNRWIKVADVDR-------DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
D + + +DR D +Y + L Y V A G+ ES V+K
Sbjct: 687 DEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGP--ESSIRVVK 744
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNGG----SPIIDYKVE---IKQEGKKW 1813
T DVPS SV +TW P+ NG +D V + ++G K
Sbjct: 745 TLEDVPSAPRNFNAELT-SATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKK 803
Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
+ + L NT Y FR+ A N G IT G PP P
Sbjct: 804 RIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQG---IPPEAPE- 859
Query: 1872 FVVSESTSRS-----VTLKWTEPESN-GGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHE 1924
+VS S R ++W P+ +PI Y + + S+ K TV G+
Sbjct: 860 -IVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLS 918
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM-VGSNIV 1983
I + ++AEN G SQ+ V SP P++++ V +
Sbjct: 919 TTISGLWMGVVYDVLLAAENREG-----RSQNATETIATPVGSPDGEPIDVQYEVMKGKI 973
Query: 1984 MTSWGTP 1990
+ SW P
Sbjct: 974 VVSWRPP 980
Score = 61.3 bits (142), Expect = 7e-09
Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 20/205 (9%)
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KTVKGKSWTKIV 1916
I K L PP P N VVS TS SV + W P+ N I Y++ + K +G+S ++
Sbjct: 334 IAKELPPP--PVNIVVSSVTSESVVITWKPPKYN--EAINKYVVNYRLKYSEGRS-SRGK 388
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGV---SLPTESQSVRLEKHATVPSPPTAPL 1973
T+ + I+ + F + + VGV SLP E+Q+ + K AT P P A
Sbjct: 389 TMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQT-KPSKPATAPVSPQA-- 445
Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNTLKF--NIRD 2030
R + + ++ WG E G + GY + D+ T E + D + +F I
Sbjct: 446 --RSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTING 502
Query: 2031 LSENHTYMIRIYARNEIGLSEPLES 2055
L + Y +R+ A+N G PL +
Sbjct: 503 LEPDSRYFVRVIAQNSEG-DSPLST 526
Score = 60.1 bits (139), Expect = 2e-08
Identities = 100/451 (22%), Positives = 177/451 (39%), Gaps = 53/451 (11%)
Query: 1641 SKYTIE--ASNTAGTSSVEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGL 1696
S+Y + A N+ G S + + V + P P ++ + + + + W PL
Sbjct: 507 SRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSS-- 564
Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
+ Y + + D + + + E + + L+ + Y FRV A + G E +E
Sbjct: 565 PVVGYTVRYNTSDGEKELTLTSPH---EKHVVTGLHPDKYYYFRVAAYSDRGQGEF--TE 619
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVE-IKQEGKKW- 1813
P++ KT +P ++SV I W P +K + Y++ + E K
Sbjct: 620 PMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTA 679
Query: 1814 -----KXXXXXXXXXARIQKLSI-----NTTY---QFRIYARNEI----GTSLPYTSDDK 1856
+ + + ++S+ T+Y Y+ EI T Y +
Sbjct: 680 NLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESS 739
Query: 1857 ITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK----- 1910
I + KTL PS PRNF +++ SV L W P + G+ + Y+ + V G+
Sbjct: 740 IRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEK 799
Query: 1911 -SWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
S +IV + S + ++++ E FR++A N G +E +S+ T P
Sbjct: 800 GSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIP 854
Query: 1969 PTAPLEIRMVGSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVD 2020
P AP EI V + + W P+ P+ YN+ +R +++ VD
Sbjct: 855 PEAP-EIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVD 913
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
L I L Y + + A N G S+
Sbjct: 914 GTDLSTTISGLWMGVVYDVLLAAENREGRSQ 944
Score = 44.0 bits (99), Expect = 0.001
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPED 577
K G T C+V G PR ++ W R + D + N L+I+ ED
Sbjct: 160 KSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREED 219
Query: 578 AGTFTCVAKNAAGFASS 594
G + C+A+N G A S
Sbjct: 220 QGKYECIARNTLGVAHS 236
Score = 38.7 bits (86), Expect = 0.045
Identities = 75/305 (24%), Positives = 109/305 (35%), Gaps = 30/305 (9%)
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGP 1672
D+ + + TS + + +L S + T+ AS G SS+ V + D PS P
Sbjct: 698 DRMSVVVPSDATSYV-LSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRN- 755
Query: 1673 VIMREI-SRESVTIEWKPPLDDGGLELTKYA----IEKHEPDNNRWIKVADV---DRDVE 1724
E+ S SV + W P G L Y + EP + K V D
Sbjct: 756 -FNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKR 814
Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
+ + L+ N EY FR+ A N G E E + I+ T P D V
Sbjct: 815 YFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSII--TQGIPPEAPEIVSVSLDRDEPPV 872
Query: 1785 Y--ITW-FPSEKNGGSPIIDYKVEIKQEG-----KKWKXXXXXXXXXARIQKLSINTTYQ 1836
I W P K +PI Y + ++ +G K K I L + Y
Sbjct: 873 VARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTT-ISGLWMGVVYD 931
Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGS 1895
+ A N G S T +G +P +P + V E + + W P E
Sbjct: 932 VLLAAENREGRSQNATETIATPVG---SPDGEPID-VQYEVMKGKIVVSWRPPSEEKRNG 987
Query: 1896 PITNY 1900
IT+Y
Sbjct: 988 NITSY 992
Score = 37.5 bits (83), Expect = 0.10
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 13/96 (13%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F KL ++ G + C GYP P++ W ++T + M DD + A +
Sbjct: 250 PYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFW-KKTDL--------MVLDDPSTAPI 300
Query: 569 ---VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V+ E FTCVA +A G +TT +I +
Sbjct: 301 GKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAK 336
Score = 36.7 bits (81), Expect = 0.18
Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 31/273 (11%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEG-PV-IMREISRESVTIEWKPPLDD---GGLELT 1699
+ A N G S T + P+G P+ + E+ + + + W+PP ++ G +
Sbjct: 934 LAAENREGRSQ-NATETIATPVGSPDGEPIDVQYEVMKGKIVVSWRPPSEEKRNGNITSY 992
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756
K + + +R+ + T+ ++N Y+F+V A G +S L
Sbjct: 993 KAILSAMDATADRYEQPVPAPSTSSTF---EVNVRRAYLFKVAAATMKGIGPYSPVLTIN 1049
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWK 1814
P AL P N + + W + S ++ Y E + + +KWK
Sbjct: 1050 PD--PAALVGPPTNVRVEATS---NSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWK 1104
Query: 1815 XXXXXXXXX------ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
A + L+ + Y F + A + + D T+ +++TP
Sbjct: 1105 QLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLA---VKNNRQGPCSDPPTVLESVTPTYM 1161
Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
+N V TS SV L W E NG + Y+
Sbjct: 1162 VQNLRVLWKTSNSVQLTW---EYNGPRNVGFYV 1191
>AF316539-1|AAK01632.1| 2200|Caenorhabditis elegans PTP-3A protein.
Length = 2200
Score = 96.3 bits (229), Expect = 2e-19
Identities = 117/527 (22%), Positives = 203/527 (38%), Gaps = 39/527 (7%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKATYENRXXX 1535
P +E + E + ++C G P+ KV W RD L + + +T N
Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCV---VGIQQKPVITISNEDIKQKHKVGDEWLV 1592
Y+CIA N G + V +++ P + + VG +
Sbjct: 211 MIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINL 270
Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
T V G P P V W K + +D T +V+ + ++ + + +T A + G
Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPS---TAPIGKNVLTLTHVESTEN--FTCVAVSALG 325
Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE--LTKYAIEKHEPDN 1710
T+ + P P +++ ++ ESV I WKPP + + + Y ++ E +
Sbjct: 326 NIEATTTVIAKELPPPPVN-IVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGRS 384
Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
+R + ++ + I L Y F V + PVG LES P+ +T P+
Sbjct: 385 SRGKTMETLENSL---VIDGLVAFQTYEFTVRSAGPVGV--GLESLPVEAQTKPSKPATA 439
Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-----IKQEGKKWK-XXXXXXXXXA 1824
++ +S+ + W P E+ G I YKV + ++WK
Sbjct: 440 PVSPQARSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMT 498
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
I L ++ Y R+ A+N G S P ++ +T+ P QP V SR + L
Sbjct: 499 TINGLEPDSRYFVRVIAQNSEGDS-PLST--LVTVATRQGIPGQPPMLTVKALDSRRMQL 555
Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
W +P + SP+ Y + + T G+ K +T+ +H + + FR++A +
Sbjct: 556 TWDKPLYS--SPVVGYTVRYNTSDGE---KELTLTSPHEKHVVTGLHPDKYYYFRVAAYS 610
Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
G TE + A++P + S V W PE
Sbjct: 611 DRGQGEFTEPMISK--TIASIPLSSPTIVSAAATSSKSVEIRWKGPE 655
Score = 66.9 bits (156), Expect = 1e-10
Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 36/301 (11%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E P +P + V + S I CR P P + W G+ I IS+ +
Sbjct: 44 EDDPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISI---KSLA 100
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV----LKIKTGEKEP---PQV-IEP- 740
S L+ V + TVV+ + + + P+V L + +K P PQ+ + P
Sbjct: 101 TGLSTLRFERVS--LDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPS 158
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP------ 794
LKS V QG++ +S +V G+PR + W ++ P L ++DG TI P
Sbjct: 159 LKS--VEQGKTAYVSCRVRGDPRAKVLWLRDLIP---LDIRADGRYSVSTIGNPGALMIQ 213
Query: 795 -KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKL 852
+ +D+G Y A N+ G+A + A + PP F + + + V G I L
Sbjct: 214 HAREEDQGKYECIARNTLGVAHSKAANLY---VKVRRVPPYFSYKLERQYVVGVGGNINL 270
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
P+P + W + + ++ + G+N+ L +T+V+S + ++ CVA ++
Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPSTAP--IGKNV-LTLTHVES---TENFTCVAVSAL 324
Query: 913 G 913
G
Sbjct: 325 G 325
Score = 64.5 bits (150), Expect = 8e-10
Identities = 206/967 (21%), Positives = 345/967 (35%), Gaps = 115/967 (11%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQL-TIDGKKQK 1162
P ++ R + V +K +F G+ L V W +G I N I + ++
Sbjct: 47 PARLVVRPDSSTVVDESKISFFCR-ADGNPLPSVIWRVNGKSITDHNRISIKSLATGLST 105
Query: 1163 LKIYDCDLDD-AGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPA------N 1211
L+ LDD A SC N ++ P + P+ L P+
Sbjct: 106 LRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQG 165
Query: 1212 TDAYLTVEIP-DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
AY++ + D V W + ++ ++++ + L+I+ E+DQ +Y C
Sbjct: 166 KTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYEC 225
Query: 1269 VLLDA-----KSTTKLKVEVVEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
+ + L V+V PP ER+Y + G ++ L +P P W
Sbjct: 226 IARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWK 285
Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
++ T P K+ LT+ VE+T+ + + G+ + V + P
Sbjct: 286 KTDLMVLDDPSTAPI--GKNV-LTLTHVESTEN--FTCVAVSALGNIEATTTVIAKELPP 340
Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
PP + + S S+ I W P+ N I YVV Y+ + +E S + KT +++N
Sbjct: 341 PPVNIVVSSVTSESVVITWKPPKY--NEAINKYVVNYR-LKYSEGRSSRG--KTMETLEN 395
Query: 1443 -LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
L + F+ Y E V +TK P P+ N D +
Sbjct: 396 SLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPAT-APVSPQARSLNRD-SI 453
Query: 1502 TCIFGGVPQPK--VTWYR---DGKKLKTAKATYENRXXXXXXXXXX------XXXXXYKC 1550
+G QP +T Y+ + T ++ +
Sbjct: 454 LVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRV 513
Query: 1551 IAFNDHGEVETSCVVGIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
IA N G+ S +V + Q P++T+ D ++ D+ L ++ + G
Sbjct: 514 IAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGY---- 569
Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK-V 1662
+ Y N + +KE +T+ + V+ + + + + G + + K +
Sbjct: 570 TVRY---NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTI 626
Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPP-------------LDDGGLELTKYA-IEKHEP 1708
P V S +SV I WK P ++ LE +K A +E E
Sbjct: 627 ASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEY 686
Query: 1709 DNNRWIKVADVDR-------DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
D + + +DR D +Y + L Y V A G+ ES V+K
Sbjct: 687 DEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGP--ESSIRVVK 744
Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNGG----SPIIDYKVE---IKQEGKKW 1813
T DVPS SV +TW P+ NG +D V + ++G K
Sbjct: 745 TLEDVPSAPRNFNAELT-SATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKK 803
Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
+ + L NT Y FR+ A N G IT G PP P
Sbjct: 804 RIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQG---IPPEAPE- 859
Query: 1872 FVVSESTSRS-----VTLKWTEPESN-GGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHE 1924
+VS S R ++W P+ +PI Y + + S+ K TV G+
Sbjct: 860 -IVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLS 918
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM-VGSNIV 1983
I + ++AEN G SQ+ V SP P++++ V +
Sbjct: 919 TTISGLWMGVVYDVLLAAENREG-----RSQNATETIATPVGSPDGEPIDVQYEVMKGKI 973
Query: 1984 MTSWGTP 1990
+ SW P
Sbjct: 974 VVSWRPP 980
Score = 61.3 bits (142), Expect = 7e-09
Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 20/205 (9%)
Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KTVKGKSWTKIV 1916
I K L PP P N VVS TS SV + W P+ N I Y++ + K +G+S ++
Sbjct: 334 IAKELPPP--PVNIVVSSVTSESVVITWKPPKYN--EAINKYVVNYRLKYSEGRS-SRGK 388
Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGV---SLPTESQSVRLEKHATVPSPPTAPL 1973
T+ + I+ + F + + VGV SLP E+Q+ + K AT P P A
Sbjct: 389 TMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQT-KPSKPATAPVSPQA-- 445
Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNTLKF--NIRD 2030
R + + ++ WG E G + GY + D+ T E + D + +F I
Sbjct: 446 --RSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTING 502
Query: 2031 LSENHTYMIRIYARNEIGLSEPLES 2055
L + Y +R+ A+N G PL +
Sbjct: 503 LEPDSRYFVRVIAQNSEG-DSPLST 526
Score = 60.1 bits (139), Expect = 2e-08
Identities = 100/451 (22%), Positives = 177/451 (39%), Gaps = 53/451 (11%)
Query: 1641 SKYTIE--ASNTAGTSSVEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGL 1696
S+Y + A N+ G S + + V + P P ++ + + + + W PL
Sbjct: 507 SRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSS-- 564
Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
+ Y + + D + + + E + + L+ + Y FRV A + G E +E
Sbjct: 565 PVVGYTVRYNTSDGEKELTLTSPH---EKHVVTGLHPDKYYYFRVAAYSDRGQGEF--TE 619
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVE-IKQEGKKW- 1813
P++ KT +P ++SV I W P +K + Y++ + E K
Sbjct: 620 PMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTA 679
Query: 1814 -----KXXXXXXXXXARIQKLSI-----NTTY---QFRIYARNEI----GTSLPYTSDDK 1856
+ + + ++S+ T+Y Y+ EI T Y +
Sbjct: 680 NLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESS 739
Query: 1857 ITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK----- 1910
I + KTL PS PRNF +++ SV L W P + G+ + Y+ + V G+
Sbjct: 740 IRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEK 799
Query: 1911 -SWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
S +IV + S + ++++ E FR++A N G +E +S+ T P
Sbjct: 800 GSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIP 854
Query: 1969 PTAPLEIRMVGSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVD 2020
P AP EI V + + W P+ P+ YN+ +R +++ VD
Sbjct: 855 PEAP-EIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVD 913
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
L I L Y + + A N G S+
Sbjct: 914 GTDLSTTISGLWMGVVYDVLLAAENREGRSQ 944
Score = 44.0 bits (99), Expect = 0.001
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPED 577
K G T C+V G PR ++ W R + D + N L+I+ ED
Sbjct: 160 KSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREED 219
Query: 578 AGTFTCVAKNAAGFASS 594
G + C+A+N G A S
Sbjct: 220 QGKYECIARNTLGVAHS 236
Score = 39.9 bits (89), Expect = 0.019
Identities = 100/460 (21%), Positives = 164/460 (35%), Gaps = 35/460 (7%)
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGP 1672
D+ + + TS + + +L S + T+ AS G SS+ V + D PS P
Sbjct: 698 DRMSVVVPSDATSYV-LSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRN- 755
Query: 1673 VIMREI-SRESVTIEWKPPLDDGGLELTKYA----IEKHEPDNNRWIKVADV---DRDVE 1724
E+ S SV + W P G L Y + EP + K V D
Sbjct: 756 -FNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKR 814
Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
+ + L+ N EY FR+ A N G E E + I+ T P D V
Sbjct: 815 YFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSII--TQGIPPEAPEIVSVSLDRDEPPV 872
Query: 1785 Y--ITW-FPSEKNGGSPIIDYKVEIKQEG-----KKWKXXXXXXXXXARIQKLSINTTYQ 1836
I W P K +PI Y + ++ +G K K I L + Y
Sbjct: 873 VARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTT-ISGLWMGVVYD 931
Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGS 1895
+ A N G S T +G +P +P + V E + + W P E
Sbjct: 932 VLLAAENREGRSQNATETIATPVG---SPDGEPID-VQYEVMKGKIVVSWRPPSEEKRNG 987
Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
IT+Y + + V E + + +F+++A G+ +
Sbjct: 988 NITSYKAILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVL 1046
Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR-DVTKTMWM 2014
++ + A V P +E + +V + + + D + R D K +
Sbjct: 1047 TINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQL 1106
Query: 2015 EVGKVD-VNTLKFN-IRDLSENHTYMIRIYA-RNEIGLSE 2051
V +D N +F + DL+ + Y + A +N + L+E
Sbjct: 1107 PVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNLTLNE 1146
Score = 37.5 bits (83), Expect = 0.10
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 13/96 (13%)
Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P F KL ++ G + C GYP P++ W ++T + M DD + A +
Sbjct: 250 PYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFW-KKTDL--------MVLDDPSTAPI 300
Query: 569 ---VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V+ E FTCVA +A G +TT +I +
Sbjct: 301 GKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAK 336
>AC024778-2|AAF60566.2| 2325|Caenorhabditis elegans Neuronal igcam
protein 4 protein.
Length = 2325
Score = 96.3 bits (229), Expect = 2e-19
Identities = 186/914 (20%), Positives = 358/914 (39%), Gaps = 83/914 (9%)
Query: 1193 EPSINFTLRLPEFILVPANTDAYLT--VEIPDETLDVTWYKKKSVIE-DTEKFTLISDVK 1249
EPS ++ P+ + V + TD + ++ W I+ D K+ L +D
Sbjct: 455 EPSQKL-IKTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTND-- 511
Query: 1250 KRTLIIRKCTEDDQCEYTCVLL--DAKSTTKLKVE---VVEFPPKIVDYEREYRIKRGSD 1304
L I + D+ EYTC + + K+T ++V ++E+ P +++ I +
Sbjct: 512 --GLAIHDIRKSDEGEYTCEISGSNVKATANVQVNGDSLIEYGPA----DQKSLIGTNVE 565
Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLE 1363
+ V + + + EW +N ++ ++ I ++ SL I++V + G Y+ R+
Sbjct: 566 FSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSLIIRQVGPDNTGEYRCRVT 625
Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
+ + + I++KP+ P + E + + + W+E + GN II + +E +
Sbjct: 626 VDGREENASAMLQIIEKPAMPERVRAELHNETMPAKVRVRWNEGFD-GNEPIIKHAIEMR 684
Query: 1421 EIDTT----EWIS-VKNITKTQ------TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
+ T +W + + NI K + T I++L+ +S+ FR A N+ S +
Sbjct: 685 TMGPTGLWSDWTTAIDNIPKEEGKPCCWTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSY 744
Query: 1470 YYKVIKETKIQSP-----TVEKPLKNITT--EPNEDIELTCIFGGVPQPKV------TWY 1516
+ ++ +P + P + +P E+++ + G V + ++ TW
Sbjct: 745 SVTMPQQPPSAAPRNVAASARSPHSVMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWN 804
Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA-FNDHGEVETSCVVGIQQKPVITI 1575
K A+ T + + + F++ EV TS + +P
Sbjct: 805 EKNLTTKDARNTLVDELITWREYEIQVAAYNKRGLGVFSESIEVTTS-----EGRPTQAP 859
Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK------NGNKLENDKEYNITTKEKTSV 1629
N +K + TA + P + YK K E K+ + +
Sbjct: 860 KNVRVKVLNSTAVAIEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLT 919
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTIEW 1687
+ EL++ T T G +KV + PE + + E+ I W
Sbjct: 920 TVVNELEKFGHYNLTTLCFTTPGDGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAVITW 979
Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
PL G+ +TKY I +H ++ +K +VD + I L + Y V+A
Sbjct: 980 NSPLKQNGI-VTKYTI-RHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTR 1037
Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
G +E ++P I +V + + P +G + I + VE
Sbjct: 1038 KG-DGPVEETKFESGVPPELPGRPSMLSIGD-ISATTVQLHFTPGF-DGHTAIRQWVVEG 1094
Query: 1807 KQ-EGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
K + + AR + L T YQ R+ A N G P S+ +
Sbjct: 1095 KMADSSVFAHVFNVSAPKARSITVTGLRPFTQYQLRLIAENVKGRGAP--SEPSRSFETL 1152
Query: 1863 LTPPSQPRNFVVSESTSR-SVTLKWTEPESN--GGSPITNYIIEFKTVKGKSWTKIVTVG 1919
T P P + +E S S+++ WT + G P Y+I ++ + ++W ++ T
Sbjct: 1153 QTNPDTPSQRLFAEPVSATSISVSWTPLLATHWNGQP-KGYLIVYREIDDENWKEVRTPA 1211
Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
EH + +++ + +EN G SLPT+ SV+ + +VPS + + G
Sbjct: 1212 LRSSEHTVTDLRPFTSYEVNVFSENGFGRSLPTD--SVKARTYESVPSGSPRNIVVTAEG 1269
Query: 1980 SNIVMTSWG-TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV-DV---NTLKFNIRDLSEN 2034
S + W E ++GY + + +++ + KV D+ +TL + DL
Sbjct: 1270 SKAAIIKWNPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPF 1329
Query: 2035 HTYMIRIYARNEIG 2048
+Y + + A +G
Sbjct: 1330 TSYHVYMSAYTIVG 1343
Score = 79.8 bits (188), Expect = 2e-14
Identities = 103/455 (22%), Positives = 174/455 (38%), Gaps = 30/455 (6%)
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPV 1673
E N+TTK+ + + + EL + + A N G + S+EVT +P++ V
Sbjct: 805 EKNLTTKDARNTL-VDELITWREYEIQVAAYNKRGLGVFSESIEVTTSE-GRPTQAPKNV 862
Query: 1674 IMREISRESVTIEWKPPLDDG--GLELT-KYAIEKHEPDNNRWIK--VADVDRDVETYCI 1728
++ ++ +V IE+ P G+ L K K EP+ K + D DR T +
Sbjct: 863 RVKVLNSTAVAIEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLTTVV 922
Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
+L + Y + G + S + + T D P + N +V ITW
Sbjct: 923 NELEKFGHYNLTTLCFTTPG--DGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAV-ITW 979
Query: 1789 FPSEKNGGSPIIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845
K G + Y + K K I L +T Y + A
Sbjct: 980 NSPLKQNGI-VTKYTIRHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRK 1038
Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
G P + K G P +P + + ++ +V L +T P +G + I +++E K
Sbjct: 1039 GDG-P-VEETKFESGVPPELPGRPSMLSIGDISATTVQLHFT-PGFDGHTAIRQWVVEGK 1095
Query: 1906 TVKGKSWTKIVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
+ + V + ++ + R+ AEN G P+E S E T
Sbjct: 1096 MADSSVFAHVFNVSAPKARSITVTGLRPFTQYQLRLIAENVKGRGAPSEP-SRSFETLQT 1154
Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTP----EWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
P P+ L V + + SW TP W+G GY I R++ W EV
Sbjct: 1155 NPDTPSQRLFAEPVSATSISVSW-TPLLATHWNGQPK--GYLIVYREIDDENWKEVRTPA 1211
Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
+ + + + DL +Y + +++ N G S P +S
Sbjct: 1212 LRSSEHTVTDLRPFTSYEVNVFSENGFGRSLPTDS 1246
Score = 72.1 bits (169), Expect = 4e-12
Identities = 86/394 (21%), Positives = 149/394 (37%), Gaps = 24/394 (6%)
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK-YAIEKHEPDNNRWIKVADVDRDVE 1724
P P + +S S+++ W P L K Y I E D+ W +V
Sbjct: 1156 PDTPSQRLFAEPVSATSISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSS 1215
Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
+ + L Y V ++N GF +L ++ + +T VPS +++
Sbjct: 1216 EHTVTDLRPFTSYEVNVFSEN--GFGRSLPTDSVKARTYESVPSGSPRNIVVTAEGSKAA 1273
Query: 1785 YITWFP-SEKNGGSPIIDYKVEIKQEGKKWKXXXX-------XXXXXARIQKLSINTTYQ 1836
I W P +E + +I YK+ + E + A++ L T+Y
Sbjct: 1274 IIKWNPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYH 1333
Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
+ A +G P S I+ P+ P +F S + + V +KW P S G
Sbjct: 1334 VYMSAYTIVGNG-PENS-TPISFETMEDVPAPPESFQCSYISEQEVRMKWLPPGSPNGK- 1390
Query: 1897 ITNYIIEF-KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS----LP 1951
ITNYII + K+ + +S + G++ ++ + F I A N+ G S
Sbjct: 1391 ITNYIISYWKSHEPRSMAIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEEAVAE 1450
Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE---WDGGAPLLGYNIAIRDV 2008
+ SVRL P+P L I+ P D +P+ ++ +
Sbjct: 1451 VMTSSVRLPVR-NAPAPVRDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQVSYQKT 1509
Query: 2009 TKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRI 2041
+ W+ + K + + + I+ LS N + RI
Sbjct: 1510 NEDEWITLEKKFEYSKRRSVIKHLSPNSMFRFRI 1543
Score = 65.7 bits (153), Expect = 3e-10
Identities = 123/608 (20%), Positives = 219/608 (36%), Gaps = 42/608 (6%)
Query: 1486 KPLKNITTEPNED-IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXX 1543
K K++T D I + C G P P + W +G +++T Y+
Sbjct: 462 KTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTNDGLAIHDIRKS 521
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
Y C + V+ + V + +I D K E+ E +
Sbjct: 522 DEGEYTCEISGSN--VKATANVQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYVRKAS 579
Query: 1604 VIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
V WY N L + I+ K S+I I+++ ++ +Y + + L+
Sbjct: 580 VEWYLNDVLLPVNGNSGLRISRNRKGSLI-IRQVGPDNTGEYRCRVTVDGREENASAMLQ 638
Query: 1662 VYDKPSKPE--GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDN--NRWIK 1715
+ +KP+ PE + E V + W DG + K+AIE P + W
Sbjct: 639 IIEKPAMPERVRAELHNETMPAKVRVRWNEGF-DGNEPIIKHAIEMRTMGPTGLWSDWTT 697
Query: 1716 VAD-VDRDVETYC----IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSX 1769
D + ++ C I+ L + FRV+A N G + +L S + + PS
Sbjct: 698 AIDNIPKEEGKPCCWTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSYSVTMPQ--QPPSA 755
Query: 1770 XXXXXXXXXIDNESVYITW-FPSEKNGGSPIIDYKVEIKQEGKK---W--KXXXXXXXXX 1823
SV + W P E+ ++ Y V + G W K
Sbjct: 756 APRNVAASARSPHSVMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWNEKNLTTKDARN 815
Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883
+ +L Y+ ++ A N+ G + ++ ++T + P P+N V S +V
Sbjct: 816 TLVDELITWREYEIQVAAYNKRGLGV-FSESIEVTTSEG-RPTQAPKNVRVKVLNSTAVA 873
Query: 1884 LKWTEPESNGGSPIT-NYIIEF---KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
+++T PE + Y ++F + KG+ + +++ + N EK F
Sbjct: 874 IEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLTTVVNELEK----FG 929
Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTA--PLEIRMVGSNIVMTSWGTPEWDGGAP 1997
T+ + P + + K T P + L I V N + +W +P G
Sbjct: 930 HYNLTTLCFTTPGDGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAVITWNSPLKQNGI- 988
Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
+ Y I + +VD +T F I L + Y + + A G P+E +
Sbjct: 989 VTKYTIRHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRKG-DGPVEETK 1047
Query: 2058 PFKVIPGE 2065
+P E
Sbjct: 1048 FESGVPPE 1055
Score = 54.8 bits (126), Expect = 6e-07
Identities = 132/654 (20%), Positives = 249/654 (38%), Gaps = 53/654 (8%)
Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
W +S +K TK +D + + TI ++ + + G VE
Sbjct: 997 WAASSPDVK----TKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRKGDGPVEETKFESGV 1052
Query: 1381 PSP-PGKPNILEI-DSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
P PG+P++L I D S+ + P G++ I +VVE + D++ + V N++ +
Sbjct: 1053 PPELPGRPSMLSIGDISATTVQLHFTPGFDGHTAIRQWVVEGKMADSSVFAHVFNVSAPK 1112
Query: 1438 T---SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNI 1491
++ L+ + Y+ R A N SE + ++ + +T +P+ +P+
Sbjct: 1113 ARSITVTGLRPFTQYQLRLIAENVKGRGAPSEPSRSFETL-QTNPDTPSQRLFAEPVSAT 1171
Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
+ + L + G P+ + YR+ + Y+
Sbjct: 1172 SISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSSEHTVTDLRPFTSYEVN 1231
Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE------VI 1605
F+++G + ++ + ++ + + V E A+I+ P E VI
Sbjct: 1232 VFSENGFGRSLPTDSVKARTYESVPSGS-PRNIVVTAEGSKAAIIKWNPVAELSTNGDVI 1290
Query: 1606 WYKNGNKLENDKEYNITTK------EKTSVIRIKELK-----RSHSSKYTIEASNTAGTS 1654
YK E + TK + T + ++ +L+ + S YTI + ++
Sbjct: 1291 GYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYHVYMSAYTIVGNGPENST 1350
Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
+ + D P+ PE IS + V ++W PP G ++T Y I + R +
Sbjct: 1351 PISFET-MEDVPAPPES-FQCSYISEQEVRMKWLPPGSPNG-KITNYIISYWKSHEPRSM 1407
Query: 1715 KV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
+ A + ++ + LN N +Y F + A+N G SE +E + L V +
Sbjct: 1408 AIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEEAVAEVMTSSVRLPVRNAPAPV 1467
Query: 1774 XXXXXIDNES-VYITWFPS-----EKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR- 1825
+ + I W S ++ SP+ +V ++ + +W R
Sbjct: 1468 RDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWITLEKKFEYSKRR 1527
Query: 1826 --IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL--TPPSQPRNFVVSESTSRS 1881
I+ LS N+ ++FRI IG L + + +TL P +QP + + S
Sbjct: 1528 SVIKHLSPNSMFRFRI---RFIGDFLESSWSPESEWMRTLPSAPFAQPISLKATPYERNS 1584
Query: 1882 VTLKWTEP-ESNGGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIKEK 1933
V L+W P +S S Y I ++ ++W HE E I K
Sbjct: 1585 VQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIAIRDEHEDKEEKILAK 1638
Score = 48.8 bits (111), Expect = 4e-05
Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Query: 1139 WFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
W +G EIQ N LT DG L I+D D GEY+CE+ S A V+ +
Sbjct: 492 WLLNGHEIQTDNVKYDLTNDG----LAIHDIRKSDEGEYTCEISGSNVKATANVQVNGDS 547
Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTL-ISDVKKRTL 1253
P T+ + E+ E + V WY ++ L IS +K +L
Sbjct: 548 LIEYGPADQKSLIGTNVEFSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSL 607
Query: 1254 IIRKCTEDDQCEYTC-VLLDAK-STTKLKVEVVEFP 1287
IIR+ D+ EY C V +D + ++++E P
Sbjct: 608 IIRQVGPDNTGEYRCRVTVDGREENASAMLQIIEKP 643
Score = 43.2 bits (97), Expect = 0.002
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 8/73 (10%)
Query: 638 KKPKAQYVDEGSD-ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K PK V G+D I++EC P P+I WL G EI D N+ + +D L
Sbjct: 462 KTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTD-NVKYDLTND------GLA 514
Query: 697 ITNVKKFQEGTYT 709
I +++K EG YT
Sbjct: 515 IHDIRKSDEGEYT 527
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
S +++W +G I+ KYD G L I + DEGEY+C + + A
Sbjct: 485 SPPPNIIWLLNGHEIQTDNVKYDLTNDG----LAIHDIRKSDEGEYTCEISGSNVKATAN 540
Query: 1102 VVELPPEIIT-RLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTID 1157
V +I +QK G F E+ K A V W+ + + + + L I
Sbjct: 541 VQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRIS 600
Query: 1158 -GKKQKLKIYDCDLDDAGEYSCEV 1180
+K L I D+ GEY C V
Sbjct: 601 RNRKGSLIIRQVGPDNTGEYRCRV 624
Score = 40.3 bits (90), Expect = 0.015
Identities = 47/219 (21%), Positives = 90/219 (41%), Gaps = 19/219 (8%)
Query: 729 TGEKEPPQ-VIEPLKSMIVRQG-ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786
T E EP Q +I+ K + V G + +++ G+P P I W N ++ K D
Sbjct: 451 TSELEPSQKLIKTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTN 510
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
+ I +K DEG YT + S A + + + E ++ I
Sbjct: 511 DGLAIHDIRK-SDEGEYTCEISGSNVKATANVQVNGDSLIEYGP-----ADQKSLIGTNV 564
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEII----SPSETITQNFDGENIELVITNVDSEIDSG 902
+ + ++ R S+ WY N+ ++ + I++N G L+I V + ++G
Sbjct: 565 EFSCEVAKEYVRK--ASVEWYLNDVLLPVNGNSGLRISRNRKG---SLIIRQVGPD-NTG 618
Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
+Y+C + + + A + I +EK + ++ E
Sbjct: 619 EYRCRVTVDGREENASAMLQI-IEKPAMPERVRAELHNE 656
Score = 37.9 bits (84), Expect = 0.078
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
T+ DKP P G ++ S+ + WDEP N +I Y+V Y+ E KN +
Sbjct: 1769 TLEDKPGPVGILRFSDVLMDSVKVSWDEPSQP-NGNVIGYIVNYKGYRMQE--EFKNEDQ 1825
Query: 1436 TQTS 1439
+TS
Sbjct: 1826 QRTS 1829
Score = 33.9 bits (74), Expect = 1.3
Identities = 19/83 (22%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 524 GSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
G+ V+F C+V E + + W+ ++ + + + + +L+IR+V P++ G +
Sbjct: 561 GTNVEFSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSLIIRQVGPDNTGEY 620
Query: 582 TC-VAKNAAGFASSTTELIVEAP 603
C V + +S I+E P
Sbjct: 621 RCRVTVDGREENASAMLQIIEKP 643
Score = 31.1 bits (67), Expect = 9.0
Identities = 32/101 (31%), Positives = 40/101 (39%), Gaps = 17/101 (16%)
Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKH----TPDGSTV-------QFECQVEGYPRPQIT 542
KL F+ S+EQ + P F +L P TP TV EC G P P I
Sbjct: 434 KLKFFDNSKSQEQ-LFP-FTSELEPSQKLIKTPKDLTVASGTDRIMMECAATGSPPPNII 491
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
W I Q + YD N L I ++ D G +TC
Sbjct: 492 WLLNGHEI---QTDNVKYDLTNDG-LAIHDIRKSDEGEYTC 528
>AY753200-1|AAV31408.1| 402|Caenorhabditis elegans UNC-89 protein.
Length = 402
Score = 92.7 bits (220), Expect = 3e-18
Identities = 97/389 (24%), Positives = 163/389 (41%), Gaps = 27/389 (6%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSI 789
+K+PP+ +E L +V+ +V G P+PT+TW + +K + SI
Sbjct: 6 QKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSI 65
Query: 790 TI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
I +K K++D G A NSEG ET A +TV ++ P F R +TV++
Sbjct: 66 KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTV----QKKPFAPEFDLRPVSLTVEKGS 121
Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSE---TITQN---FDGENIELVIT-NVDSEIDS 901
A P+P+ W N + + +T++ DG +I + T SE++
Sbjct: 122 EAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNH 181
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI--LECQTSHTVSTK 959
VA N+ G GA++TI+ +K K + KT + E H K
Sbjct: 182 LTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATECK 241
Query: 960 WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET 1015
W+ + KEI+ + ++ + G + + + ET T L V ET
Sbjct: 242 WFLDGKEITTAQGVTVSKDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLET 301
Query: 1016 -----IPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH 1070
PEF KL+D EV + D ++V I + W ++G +++ KN + +
Sbjct: 302 PKETKKPEFTDKLRDMEVTKGDTVQMDV-IALHSPLYKWYQNGNLLEDGKNGVTIKNEEN 360
Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
L I N D G+ + +E ++E
Sbjct: 361 KSSLIIPN--AQDSGKITVEASNEVGSSE 387
Score = 85.4 bits (202), Expect = 4e-16
Identities = 98/431 (22%), Positives = 168/431 (38%), Gaps = 39/431 (9%)
Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
E+Q P FVE L K +TV FE +VEG P+P +TW+ + +K S ++ D
Sbjct: 4 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 63
Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXX 622
++ + I+ + EDAG VA N+ G + +L V+ P + V
Sbjct: 64 SI-KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSE 122
Query: 623 XXXADILEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
+ GIP PT+ + V +G + G + DE+
Sbjct: 123 AVFSAHAFGIPLPTYEWSVNGRKVRDGQE--------------------GARVTRDES-- 160
Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
D ++ T + T +VVA N G L I+ + P++ L
Sbjct: 161 ---TVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDL 217
Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKD 799
K V + + + +VV W + K + T S D +
Sbjct: 218 KLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVSKDDQFEFRCSIDTTMFG 275
Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
G ++ A N+ G ET + V E +E +P F ++ +++ V + T+++ +
Sbjct: 276 SGTVSVVASNAAGSVETKTELKVLETPKETKKPE-FTDKLRDMEVTKGDTVQMDVIALHS 334
Query: 860 PVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
P+ WY+N ++ + +T + L+I N DSG ASN G S
Sbjct: 335 PL--YKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DSGKITVEASNEVGSSESS 389
Query: 919 ARVTIDVEKVT 929
A++T++ T
Sbjct: 390 AQLTVNPPSTT 400
Score = 84.6 bits (200), Expect = 7e-16
Identities = 94/403 (23%), Positives = 174/403 (43%), Gaps = 42/403 (10%)
Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDG 885
E+ +PP F+ + T T+ RV P P++TWY E + S+ + + FDG
Sbjct: 4 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 63
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ---KSYETEE 942
+I++ I N+ E D+G+ + VA+NS G A++T V+K F S E+
Sbjct: 64 -SIKISIKNIKIE-DAGEIRAVATNSEGSDETKAKLT--VQKKPFAPEFDLRPVSLTVEK 119
Query: 943 GKTVILECQT--SHTVSTKWYHNKKEI-SGMDHREIIQ-----EGRXXXXXXXXXXXXDV 994
G + + +W N +++ G + + + +G +V
Sbjct: 120 GSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEV 179
Query: 995 G--VIKCIVKD----QETSTMLVV---KETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
I + ++ +ET L + K P+ R L+ V + D+A EV + T
Sbjct: 180 NHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHAT- 238
Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVT 1101
+ W DG+ I + K +T++ G S + + + E+
Sbjct: 239 ECKWFLDGKEITTAQG-VTVSKDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELK 297
Query: 1102 VVELP-----PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI 1156
V+E P PE +L++ +V KG+ ++ + L +W+++G+ ++ + +TI
Sbjct: 298 VLETPKETKKPEFTDKLRDMEVTKGDTVQMDV-IALHSPLYKWYQNGNLLEDGKN-GVTI 355
Query: 1157 DGKKQKLKIYDCDLDDAG----EYSCEVGNSKCTAILTVEEPS 1195
++ K + + D+G E S EVG+S+ +A LTV PS
Sbjct: 356 KNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPS 398
Score = 82.2 bits (194), Expect = 4e-15
Identities = 84/348 (24%), Positives = 143/348 (41%), Gaps = 31/348 (8%)
Query: 633 PPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
PP F + K + VD + ++ E R+ P+P + W KGEE+ + + + E D +
Sbjct: 9 PPKFVEILVDKTETVD--NTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR-EFDGSI 65
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
S I N+K G VA N EG L ++ P + P+ S+ V +G
Sbjct: 66 KIS---IKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPV-SLTVEKGS 121
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVK-----DE 800
+ SA G P PT W N + V+ A T+ + +IL +
Sbjct: 122 EAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNH 181
Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
++ AEN+ G ET A +T+ EP + A + Q + + ++V
Sbjct: 182 LTISVVAENTLGAEETGAQLTI-EPKKPPAPKLTRDLKLQTVNKTDLAHFEVVV----EH 236
Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
W+ + + I+ ++ +T + D + E + + SG VASN+AG
Sbjct: 237 ATECKWFLDGKEITTAQGVTVSKD-DQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTE 295
Query: 921 VTI-----DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN 963
+ + + +K F L + E +G TV ++ H+ KWY N
Sbjct: 296 LKVLETPKETKKPEFTDKL-RDMEVTKGDTVQMDVIALHSPLYKWYQN 342
Score = 65.3 bits (152), Expect = 5e-10
Identities = 86/396 (21%), Positives = 147/396 (37%), Gaps = 16/396 (4%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PPK V+ + + V V + P+P W + + +K+ + S ++
Sbjct: 9 PPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKIS 68
Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG---KPNILEIDSSSINICWDE 1403
IK ++ DAG + N+ G + + +T+ KP P +P L ++ S +
Sbjct: 69 IKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAH 128
Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDI 1461
T + V + D E V T SI + T + Y + V
Sbjct: 129 AFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVA 188
Query: 1462 SDA--SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
+ +E T I+ K +P + + LK T + + + K W+ DG
Sbjct: 189 ENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATECK--WFLDG 246
Query: 1520 KKLKTAKATYENRXXXX----XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
K++ TA+ ++ +A N G VET + + + P T
Sbjct: 247 KEITTAQGVTVSKDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETK 306
Query: 1576 SNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
E D + +V V + + P WY+NGN LE+ K +T K + + +
Sbjct: 307 KPEFTDKLRDMEVTKGDTVQMDVIALHSPLYKWYQNGNLLEDGKN-GVTIKNEENKSSLI 365
Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
S K T+EASN G+S L V + P
Sbjct: 366 IPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTP 401
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/218 (23%), Positives = 91/218 (41%), Gaps = 21/218 (9%)
Query: 1485 EKPLK--NITTEPNEDIELTCIFG----GVPQPKVTWYRDGKKLKTAKAT----YENRXX 1534
+KP K I + E ++ T +F G P+P VTWY G++LK + ++
Sbjct: 7 KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIK 66
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVT 1593
+ +A N G ET + +Q+KP + + G E + +
Sbjct: 67 ISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFS 126
Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--------TI 1645
A GIP P W NG K+ + +E T+++++V L ++ Y ++
Sbjct: 127 AHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISV 186
Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
A NT G L + +P KP P + R++ ++V
Sbjct: 187 VAENTLGAEETGAQLTI--EPKKPPAPKLTRDLKLQTV 222
Score = 47.2 bits (107), Expect = 1e-04
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
Q+KP + E + K + D +V V +EG P P V WY G +L+ I +
Sbjct: 6 QKKPPKFV--EILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 63
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
+ I IK +K + + A+N+ G+ + L V KP PE
Sbjct: 64 SIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPE 107
Score = 46.8 bits (106), Expect = 2e-04
Identities = 59/295 (20%), Positives = 118/295 (40%), Gaps = 23/295 (7%)
Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISD 1463
E T+ +Y+ + +E+ ++ + ++ + + SI+N+K + RA A N S+
Sbjct: 34 EGEPKPTVTWYL-KGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATN----SE 88
Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
S+ T+ K+ + K +P + ++T E + + G+P P W +G+K++
Sbjct: 89 GSDETKA-KLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVR 147
Query: 1524 T----AKATYENRXXXXXXXXXXXXXXXYK--------CIAFNDHGEVETSCVVGIQ-QK 1570
A+ T + Y +A N G ET + I+ +K
Sbjct: 148 DGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKK 207
Query: 1571 PVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
P D+K Q D V+E E W+ +G ++ + ++ ++
Sbjct: 208 PPAPKLTRDLKLQTVNKTDLAHFEVVVEHAT--ECKWFLDGKEITTAQGVTVSKDDQFEF 265
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
+ S ++ ASN AG+ + LKV + P + + P ++ VT
Sbjct: 266 RCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVT 320
Score = 45.2 bits (102), Expect = 5e-04
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 7/110 (6%)
Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
+L V E P +++ P F +KLR G TVQ + V P W++ +++
Sbjct: 295 ELKVLETP---KETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGNLLEDG 349
Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
++ +++N ++L+I +D+G T A N G + S+ +L V P
Sbjct: 350 KNGVTIKNEENKSSLIIPNA--QDSGKITVEASNEVGSSESSAQLTVNPP 397
Score = 37.5 bits (83), Expect = 0.10
Identities = 56/314 (17%), Positives = 120/314 (38%), Gaps = 18/314 (5%)
Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVE 1282
VTWY K ++ +++ + + I+ +D E V +++ + KL V+
Sbjct: 41 VTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 100
Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK----CKHTKPSI 1338
F P+ +++GS+ P P EW VN + ++ + T+
Sbjct: 101 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 160
Query: 1339 DSKSASLTIKKVENTDAGIYKLRL----ENNCGHADVEMNVTI-LDKPSPPGKPNILEID 1393
AS+ + + L + EN G + +TI KP P L++
Sbjct: 161 TVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTIEPKKPPAPKLTRDLKLQ 220
Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
+ + ++T + ++ +EI T + ++V Q + + +
Sbjct: 221 TVNKTDLAHFEVVVEHATECKWFLDGKEITTAQGVTVSK--DDQFEFRCSIDTTMFGSGT 278
Query: 1454 YAVNEVDISDASETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
+V + + + ET KV++ K + P L+++ + +++ I + P
Sbjct: 279 VSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPL 336
Query: 1513 VTWYRDGKKLKTAK 1526
WY++G L+ K
Sbjct: 337 YKWYQNGNLLEDGK 350
Score = 36.3 bits (80), Expect = 0.24
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 14/125 (11%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+
Sbjct: 9 PPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKIS 68
Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
I + ++DAGE NS + A LTV++ PEF L P + LTVE
Sbjct: 69 IKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPF-----APEFDLRPVS----LTVEK 119
Query: 1221 PDETL 1225
E +
Sbjct: 120 GSEAV 124
>AY130758-3|AAN61519.1| 10578|Caenorhabditis elegans 1MDa_1 protein
protein.
Length = 10578
Score = 89.8 bits (213), Expect = 2e-17
Identities = 99/445 (22%), Positives = 176/445 (39%), Gaps = 37/445 (8%)
Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQ 557
P + + AP VE L DG + C++ P + W + ++ ++D
Sbjct: 812 PPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVT 871
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXX 615
D V L+ E F EDAG + C A N G A + + VE + DH E +
Sbjct: 872 TTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDH-EEAEISE 930
Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQ--YVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
D+ +PP F + A+ + + + + ++ ++W G +
Sbjct: 931 SVLTD------DVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMD 984
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
I +E V +D ++ TN+ G YT A + G ++ +++ +
Sbjct: 985 IYENEKYEVMQFADGAQILTIRAPTNL---DSGVYTCTAESEHGVSNSSCQVELTISAES 1041
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
P+ E ++ + E V + G K A K + + +
Sbjct: 1042 SPESFEKVE---ITPPEEV----KETGIDDDIEVILKEEVSGTAQIEKREEEFKLLV--- 1091
Query: 794 PKKVKDEGVYTLKAE-NSEGIAE-TSAVITVEEPTEEN----AEPPLFINRFQEITVKEK 847
KV D+ TL A E + E ++ E+ E+N + P F E VKE
Sbjct: 1092 --KVADQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQEPRFETSTDEYHVKEN 1149
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
GTIK+ A ++ +P P + WY E + S+ ++ ++ +++ NV G+Y
Sbjct: 1150 GTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKR-QGGNYFLR 1208
Query: 908 ASNSAGKSSHGARVTID-VEKVTFV 931
A N G+S ++T+D +E VT V
Sbjct: 1209 AHNCHGESILPMKLTVDPIEAVTHV 1233
Score = 82.6 bits (195), Expect = 3e-15
Identities = 108/496 (21%), Positives = 203/496 (40%), Gaps = 54/496 (10%)
Query: 502 TSEEQSMAPIFVEKL--RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
+S S P FV L R HT + + +C+ G P P W + ++ Q +Q+
Sbjct: 3889 SSITSSTRPHFVVPLPERVTHTVNDH-ITIKCKFSGQPLPAAMW-EKDGVLLDLQKYQVT 3946
Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH-GSEMT-VXXXX 617
+D + L I +D +TC N AG S++ + V + DH G + T +
Sbjct: 3947 -TEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDV---VDDHLGLQQTGLHVMC 4002
Query: 618 XXXXXXXXADILE----------GIPP---TFSKKPKAQYVDEGSDIL------LECRLV 658
DIL PP T +++P + ++ L+C ++
Sbjct: 4003 ERDQNDVELDILVQSPNHLGVTFNFPPVNRTLARQPPYFLLPLSDKVVIDEKCTLKCVVM 4062
Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
IP + W+ G + D+N + E + ++L++ N+KK + A+N +G+
Sbjct: 4063 GIPLVIVKWIVDGVVVTEDDNHEIHFEDGI----ALLRMKNIKK-DKSVVQCEAINCKGK 4117
Query: 719 ASLPIVL------KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
+ VL + + G+ + P + LK + L VVG P P ++ N
Sbjct: 4118 VTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTT-DHATLKCIVVGTPLPDVSCSFNG 4176
Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEG-VYTLKAENSEGIAETSAVITVEEPTEENAE 831
+ DG I +++ V +EG V N G + ++ V+ + + E+N +
Sbjct: 4177 VTDNSKIRSEDG----IVLIQVNDVTEEGIVVECTISNETGSSTSNCVVKIIKQEEKNYQ 4232
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIEL 890
P+ + Q +V + + + V +P P++ W N + I F DG I L
Sbjct: 4233 RPIIVFN-QAGSVNNERELSVKVGVIASPEPTLFWKHNGKSIEEGGDYYLIFEDGIGI-L 4290
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE---KVTFVKHLQKSYETEEGKTVI 947
+ N+ S ++ C+A N G+++ V I ++ K+T VK L ++ +
Sbjct: 4291 KVFNIQD--GSHEFTCIAKNEYGQTTVEIPVEIGLKTENKLTLVKTLNDIAVVDDIVQLK 4348
Query: 948 LECQTSHTVSTKWYHN 963
+ + + KW+ +
Sbjct: 4349 IVAEGDLPIEFKWFED 4364
Score = 78.6 bits (185), Expect = 5e-14
Identities = 63/261 (24%), Positives = 114/261 (43%), Gaps = 7/261 (2%)
Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
N++ + + D W+ V+ E+ + + L + K ++ Y VL
Sbjct: 8760 NSEVIIKCKTSQPISDAKWFCNGMVLLPDEQVNMTVTGCEAVLRLVKFLPQNKGNYH-VL 8818
Query: 1271 LDAKSTTKLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
+D ++ + PP I++ + + G T ++ P P + N + +
Sbjct: 8819 IDGSIGSQPAILSGPVPPVILNKLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVS 8878
Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
K I ASL I K+ D G Y + LEN G + ++++T++D P P K +
Sbjct: 8879 F--DVKYEIYDNIASLYIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKPRKAQL 8936
Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSS 1448
+ + +S W P +TG S I++Y+V + ++ W ++ ++ KT T+I+ L N
Sbjct: 8937 VALTDTSATFKW-LPPHTGESDILHYIVMRRSTESRRWRNIGHVQEKTFTAIE-LVPNEF 8994
Query: 1449 YRFRAYAVNEVDISDASETTE 1469
Y FR AVN SE E
Sbjct: 8995 YAFRIVAVNGFGEGAPSEIIE 9015
Score = 75.8 bits (178), Expect = 3e-13
Identities = 127/625 (20%), Positives = 226/625 (36%), Gaps = 65/625 (10%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
DGS ++ P W ++ +Q+ + D++N + + ++ P G T
Sbjct: 608 DGSPLKLRVMASSLPPATFLWMLNNFELRSNQNVTIRNDEENSSEIEFQKA-PN--GNVT 664
Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
AKN G T ++I++ G ++T A I + +P
Sbjct: 665 VSAKNHLGEDRWTGKVILQYESPPPGQKITTIEKVTESWTLEEAVITQVVPTA------- 717
Query: 643 QYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
D G I++ R + W G I E VA+ES + S L + +
Sbjct: 718 --ADPGDRIVIIVRFDENKTSNCQFNWTINGVNIEKLEENLVAVESTE--FESSLIVEKL 773
Query: 701 KKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKE------------PPQVIEPLKSMIVR 747
++ G V N+ GE S L+I+ + P+++EPL S
Sbjct: 774 EEQLCGEVVCVVKNQHGEVFSSSAHLRIRDDDSSFEIVPPNLPEECAPKIVEPLHSASFL 833
Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI-----TILKPK-KVKDEG 801
G+++ L ++ NP + W K++ V+ D T + +L P+ +D G
Sbjct: 834 DGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCELLNPECFAEDAG 893
Query: 802 VYTLKAENSEGIAETSAVITVEE----PTEENAE--------------PPLFINRFQEIT 843
+Y A N G AET+A I VE E AE PP FI T
Sbjct: 894 LYKCTATNPHGTAETAAFINVEGAEYIKDHEEAEISESVLTDDVHIILPPKFIETLTAET 953
Query: 844 --VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
++ G +++VA V +++W ++ I +E + +++ + +DS
Sbjct: 954 DNFQQLGYVRMVATVRSVAPITVSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDS 1013
Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET------EEGKTVILECQTSHT 955
G Y C A + G S+ +V + + + + +K T E G +E
Sbjct: 1014 GVYTCTAESEHGVSNSSCQVELTISAESSPESFEKVEITPPEEVKETGIDDDIEVILKEE 1073
Query: 956 VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET 1015
VS K+E ++ + V K + + E +
Sbjct: 1074 VSGTAQIEKREEEFKLLVKVADQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQ 1133
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
P F ++ VKE + I+ T + W E ++ +N + + G +
Sbjct: 1134 EPRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAG-TSAI 1192
Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE 1099
++N G Y LR +C E
Sbjct: 1193 ILKNVQKRQGGNY--FLRAHNCHGE 1215
Score = 70.9 bits (166), Expect = 9e-12
Identities = 55/202 (27%), Positives = 85/202 (42%), Gaps = 19/202 (9%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536
+P + L + N + L +F GVPQP ++W D +L + EN
Sbjct: 3788 APVFTERLPSSACFANSKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAI 3847
Query: 1537 XXXXXXXXXXXY-KCIAFNDHGEVETSC-VVGIQQKPVITISNEDIKQK----------- 1583
+ KC A N G+VETSC +V + VI+ S+ +
Sbjct: 3848 RFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERV 3907
Query: 1584 -HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
H V D + G P P +W K+G L+ K Y +TT++ TS+++I+ +
Sbjct: 3908 THTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQK-YQVTTEDGTSILKIESASLDDKAV 3966
Query: 1643 YTIEASNTAGTSSVEVTLKVYD 1664
YT +N AG S T+ V D
Sbjct: 3967 YTCTIANEAGCESTSCTIDVVD 3988
Score = 70.5 bits (165), Expect = 1e-11
Identities = 75/349 (21%), Positives = 142/349 (40%), Gaps = 28/349 (8%)
Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
H+ G + G P P + NG + D +Y I + + + I ++ + +Y
Sbjct: 8848 HQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIY--DNIASLYIPKMSKRDGGEY 8905
Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
T+ N G ++ + + D P KP ++ ++ S T +W PP G ++ Y +
Sbjct: 8906 TVVLENKYGKDESDLHITMVDTPLKPRKAQLV-ALTDTSATFKWLPP-HTGESDILHYIV 8963
Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT- 1762
+ ++ RW + V +T+ +L N Y FR++A N GF E SE I + T
Sbjct: 8964 MRRSTESRRWRNIGHVQE--KTFTAIELVPNEFYAFRIVAVN--GFGEGAPSEIIEVNTL 9019
Query: 1763 ------ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
+ D ++NE +T E++ I+ ++K++ KK K
Sbjct: 9020 DYDQEESFDFAGEEELKLDDVQVNNE--VVTEITIEES--EVTIEEHRKLKKKSKKSKKT 9075
Query: 1817 XXXXXXXARIQ-KLSINTTYQFRIYARNEIGTSLPYTSD--------DKITIGKTLTPPS 1867
+ I ++S + T I + I + P + + + T+ K P
Sbjct: 9076 TDEPELDSEIALEVSSDITSSLEITTESTIPDTAPESQETLNVEIAVTETTVQKITNPSD 9135
Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
+ V+E T+ S +K + + N S + + K ++GK KI+
Sbjct: 9136 ESAKKDVNEDTAVSSIVKKDDKDVNKKSLPESGLTTKKEIQGKPEKKIM 9184
Score = 68.1 bits (159), Expect = 6e-11
Identities = 63/273 (23%), Positives = 109/273 (39%), Gaps = 8/273 (2%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXX 1538
SP + +P+ TE + + T F P V W RD ++++ A KA+ E
Sbjct: 10253 SPFISQPVSATVTEMAGEAKFTVKFSRKPI-YVKWMRDDREIRVAYGKASVETTDDSSVL 10311
Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
I E ++ + ++ IT+ + + G ++ I
Sbjct: 10312 VIKNIDGKDVGNIYAVFDSEYRSAMARLDLRVPCKITLESSSNAPEIVAGKNLDLSFKIS 10371
Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
G P P I + N+ + ++T + + IR+K LK S + I N + +
Sbjct: 10372 GYPLPTNIELLHNNENLRTRS-DVTDFDDSISIRMKRLKLEDSGEIKIIGKNDSSEDQLR 10430
Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+ + V + SKP + + RE+VT+ W P + G + +Y +E+ D RW
Sbjct: 10431 IPINVIEVTSKPTS-LQVTSTERETVTLTWSLPTELNGSNVNEYLVERKTVDGGRWRHAC 10489
Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
V + L EY+FRV+A N G S
Sbjct: 10490 TVTD--SRAVVDGLFSGTEYVFRVVAVNGAGQS 10520
Score = 63.3 bits (147), Expect = 2e-09
Identities = 55/269 (20%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
D + V + K D +I ++ + + D + LD + K+ +
Sbjct: 10290 DREIRVAYGKASVETTDDSSVLVIKNIDGKDVGNIYAVFDSEYRSAMARLDLRVPCKITL 10349
Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
E P+IV G ++ L +P P + ++++ + + D
Sbjct: 10350 ESSSNAPEIV---------AGKNLDLSFKISGYPLPTNIELLHNNENLRTRSDVTDFDD- 10399
Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
S S+ +K+++ D+G K+ +N+ + + + +++ S P + + ++ + W
Sbjct: 10400 SISIRMKRLKLEDSGEIKIIGKNDSSEDQLRIPINVIEVTSKPTSLQVTSTERETVTLTW 10459
Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
P S + Y+VE + +D W +T ++ + L + + Y FR AVN
Sbjct: 10460 SLPTELNGSNVNEYLVERKTVDGGRWRHACTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQ 10519
Query: 1462 SDASE----TTEYYKVIKETKIQSPTVEK 1486
S S+ TT+ + I ET SP VEK
Sbjct: 10520 SAPSDTIEATTQAEEEIDETVPTSP-VEK 10547
Score = 62.5 bits (145), Expect = 3e-09
Identities = 39/152 (25%), Positives = 75/152 (49%), Gaps = 11/152 (7%)
Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRNFVVSESTSRSVT 1883
R+++L + + + +I +N+ +S+D++ I + S+P + V+ + +VT
Sbjct: 10404 RMKRLKLEDSGEIKIIGKND-------SSEDQLRIPINVIEVTSKPTSLQVTSTERETVT 10456
Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
L W+ P GS + Y++E KTV G W TV S ++ + E +FR+ A
Sbjct: 10457 LTWSLPTELNGSNVNEYLVERKTVDGGRWRHACTVTDS--RAVVDGLFSGTEYVFRVVAV 10514
Query: 1944 NTVGVSLPTESQSVRLEKHATV-PSPPTAPLE 1974
N G S P+++ + + + PT+P+E
Sbjct: 10515 NGAGQSAPSDTIEATTQAEEEIDETVPTSPVE 10546
Score = 61.7 bits (143), Expect = 6e-09
Identities = 121/594 (20%), Positives = 223/594 (37%), Gaps = 57/594 (9%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP+F E+L S + E G P+P I+W + + ++ V+ +
Sbjct: 3788 APVFTERLPSSACFANSKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAI 3847
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE---APLSDHGSEMTVXXXXXXXXXXXX 625
V G C A N AG ++ E++ + +SD +
Sbjct: 3848 RFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERV 3907
Query: 626 ADILEG---IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE---- 678
+ I FS +P + E +LL+ + + D + K E D+
Sbjct: 3908 THTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKYQVTTEDGTSILKIESASLDDKAVY 3967
Query: 679 NISVAIESDMH-MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---------- 727
++A E+ C++ + + Q+ V+ + + L I+++
Sbjct: 3968 TCTIANEAGCESTSCTIDVVDDHLGLQQTGLHVMCERDQNDVELDILVQSPNHLGVTFNF 4027
Query: 728 ----KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783
+T ++PP + PL +V E L V+G P + W + V
Sbjct: 4028 PPVNRTLARQPPYFLLPLSDKVVID-EKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEI 4086
Query: 784 GDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVIT---VEEPTEENAEPPLFINRF 839
I +L+ K + KD+ V +A N +G TS V+T VEE + + P F+
Sbjct: 4087 HFEDGIALLRMKNIKKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSL 4146
Query: 840 QE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
++ T + T+K + V P+P ++ N ++ + I ++ DG +V+ V+
Sbjct: 4147 KDTCTTTDHATLKCI--VVGTPLPDVSCSFNG--VTDNSKI-RSEDG----IVLIQVNDV 4197
Query: 899 IDSG-DYKCVASNSAGKSSHGARVTI------DVEKVTFVKHLQKSYETEEGKTVILECQ 951
+ G +C SN G S+ V I + ++ V + S E +V +
Sbjct: 4198 TEEGIVVECTISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVI 4257
Query: 952 TSHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETST 1008
S + W HN K I G D+ I ++G CI K++ +T+
Sbjct: 4258 ASPEPTLFWKHNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSH--EFTCIAKNEYGQTTV 4315
Query: 1009 MLVVK-----ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
+ V+ E ++ L D V + V + V + W DG+I++
Sbjct: 4316 EIPVEIGLKTENKLTLVKTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILE 4369
Score = 56.4 bits (130), Expect = 2e-07
Identities = 50/205 (24%), Positives = 95/205 (46%), Gaps = 11/205 (5%)
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLK--NITTEPNEDIELTCIFGGV--PQP 1511
V E IS+ + ++ V+K K + ++P+ N N + EL+ G + P+P
Sbjct: 4203 VVECTISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEP 4262
Query: 1512 KVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVG 1566
+ W +GK ++ Y E+ + CIA N++G+ VE +G
Sbjct: 4263 TLFWKHNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSHEFTCIAKNEYGQTTVEIPVEIG 4322
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
++ + +T+ + + V D + V EG P E W+++G LE+D + IT +
Sbjct: 4323 LKTENKLTLV-KTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKC 4381
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTA 1651
S +++K L+ + + T E SN++
Sbjct: 4382 ISTLQLK-LEETGTRIITCEVSNSS 4405
Score = 55.2 bits (127), Expect = 5e-07
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
S AP F+ KL G VQ +C + G P+P+I W I P+ ++ + Y +
Sbjct: 1672 SSAAPQAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVY-E 1730
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAG 590
D V L I ED G + C A N AG
Sbjct: 1731 DGVCILRIESTLIEDEGEYCCTASNVAG 1758
Score = 53.2 bits (122), Expect = 2e-06
Identities = 50/196 (25%), Positives = 87/196 (44%), Gaps = 17/196 (8%)
Query: 631 GIPPTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
G + + PK+ V + S+++++C+ + P D W G ++PDE +++ +
Sbjct: 8742 GTGQSIIEHPKSHAVGQMNSEVIIKCK-TSQPISDAKWFCNGMVLLPDEQVNMTVTG--- 8797
Query: 690 MYC-SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
C +VL++ +G Y V+ G S P +L PP ++ L I Q
Sbjct: 8798 --CEAVLRLVKFLPQNKGNYHVLIDGSIG--SQPAIL----SGPVPPVILNKLTKPITHQ 8849
Query: 749 -GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLK 806
G+S +G P P + N +PV + K + + ++ PK K D G YT+
Sbjct: 8850 AGKSFTYKFNFMGAPAPRLRVLSNGEPV-SFDVKYEIYDNIASLYIPKMSKRDGGEYTVV 8908
Query: 807 AENSEGIAETSAVITV 822
EN G E+ IT+
Sbjct: 8909 LENKYGKDESDLHITM 8924
Score = 52.4 bits (120), Expect = 3e-06
Identities = 70/302 (23%), Positives = 124/302 (41%), Gaps = 45/302 (14%)
Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGE 1086
V E ++ VE++ V W +D + + + + + +G+ R + I NT V D+G
Sbjct: 3014 VMEGQPTVITVELDDPNVIVNWLKDRRPLHENERIRLETDGQGNHRVI-IPNTCVGDQGT 3072
Query: 1087 YSCILRDESCTAEVTVVELPPE----IITR--------LQNQKVNKGNKATFEIELTKGD 1134
Y + ES + V E E +I +Q V G+ AT EL + +
Sbjct: 3073 YLALTSSESVAITLVVEERIEEKEVMVIASGTESEEDDVQEYLVPPGSTATIACELEECE 3132
Query: 1135 AL--VRWFKDGSEIQF----SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
+RW +DG +I+F + H+Q +G K L ++D D+G Y E +C
Sbjct: 3133 LKRSIRWLRDGKDIRFEQGKTEHVQ---NGLKHYLVVHDATSLDSGLYKTERSEEQC--- 3186
Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTL--I 1245
E ++P A + + + + W K ++I D +F +
Sbjct: 3187 ---------------EETIIPRGVVATIQCQTSEPQESIQWSKDGNIIPSDISRFEFRSL 3231
Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305
+ + ++I + D Y+ VL++ KS+ K+ VVE E E + DV
Sbjct: 3232 DNNQSHEMVISNISWSDAGVYS-VLINGKSSFVSKIVVVESELITQSVEEEPEAEPEIDV 3290
Query: 1306 TL 1307
+L
Sbjct: 3291 SL 3292
Score = 48.4 bits (110), Expect = 6e-05
Identities = 22/78 (28%), Positives = 43/78 (55%)
Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
++G+ + +I G+P PE+ W +G+ + + EY+I ++ ++RI+ +Y
Sbjct: 1691 RIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYC 1750
Query: 1645 IEASNTAGTSSVEVTLKV 1662
ASN AGT+ + LK+
Sbjct: 1751 CTASNVAGTTFSKCYLKL 1768
Score = 48.0 bits (109), Expect = 7e-05
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F +K + G + L+C + +P+P+I W G+ IVP++ S+ E + C
Sbjct: 1679 PKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGV---C- 1734
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
+L+I + EG Y A N G LK+ + + ++ L +
Sbjct: 1735 ILRIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDDAVDLLRQLSEI 1785
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/311 (20%), Positives = 115/311 (36%), Gaps = 24/311 (7%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL---VR 1138
H+E E S ES + + LPP+ I L + N + T V
Sbjct: 923 HEEAEIS-----ESVLTDDVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVS 977
Query: 1139 WFKDGSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCE------VGNSKCTAILT 1190
W KDG +I + ++ DG Q L I D+G Y+C V NS C LT
Sbjct: 978 WQKDGMDIYENEKYEVMQFADGA-QILTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELT 1036
Query: 1191 VEEPSINFTLRLPEFI----LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLIS 1246
+ S + E + D + V + +E +K+ E+ + ++
Sbjct: 1037 ISAESSPESFEKVEITPPEEVKETGIDDDIEVILKEEVSGTAQIEKRE--EEFKLLVKVA 1094
Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
D TL+ E ++ ++E + P+ EY +K +
Sbjct: 1095 DQVASTLVANVFLEAVHEAVKKIVETEDEEEDNQIEATQ-EPRFETSTDEYHVKENGTIK 1153
Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
+ P P EW + ++ ++ ++ ++++ +K V+ G Y LR N
Sbjct: 1154 MAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCH 1213
Query: 1367 GHADVEMNVTI 1377
G + + M +T+
Sbjct: 1214 GESILPMKLTV 1224
Score = 46.0 bits (104), Expect = 3e-04
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
PP FI + V TI LV V +P W+ N + + Q G NI +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVGHGINISRL 148
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
S + G YKCV N AG S+ +T++ ++ +HL S E
Sbjct: 149 KV---SRPEQGVYKCVTRNPAGVSTSYGYITVNADR----EHLSSSKE 189
Score = 45.6 bits (103), Expect = 4e-04
Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F +V E I + + P P + W F E++ +N+S+ E+ S
Sbjct: 1135 PRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGT----S 1190
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG---E 750
+ + NV+K Q G Y + A N GE+ LP+ L + E + + ++V Q E
Sbjct: 1191 AIILKNVQKRQGGNYFLRAHNCHGESILPMKLTVDPIEAVTHVLETSIPKVVVEQDAKEE 1250
Query: 751 SVILSAQVV 759
V +A+++
Sbjct: 1251 EVRRAAEII 1259
Score = 45.6 bits (103), Expect = 4e-04
Identities = 86/421 (20%), Positives = 178/421 (42%), Gaps = 53/421 (12%)
Query: 831 EPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
+PP F+ + + + EK T+K V V P+ + W + +++ + +F+
Sbjct: 4037 QPPYFLLPLSDKVVIDEKCTLKCV--VMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIAL 4094
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---------DVEKVTFVKHLQKSYET 940
L + N+ D +C A N GK + +T D++K +FV L+ + T
Sbjct: 4095 LRMKNIKK--DKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTT 4152
Query: 941 EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
+ T L+C V T +G+ I+ + V++C
Sbjct: 4153 TDHAT--LKCIV---VGTPLPDVSCSFNGVTDNSKIRSEDGIVLIQVNDVTEEGIVVECT 4207
Query: 1001 VKDQETST-----MLVVKETIPEFIRKLQDFEV-----KEKDVAILEVEINSETADVVWE 1050
+ ++ S+ + ++K+ + R + F E+++++ I S + W+
Sbjct: 4208 ISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWK 4267
Query: 1051 RDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
+G+ I+ + Y FE I K++ H E++CI ++E T VE+P EI
Sbjct: 4268 HNGKSIEEGGDYYLIFEDGIGILKVFNIQDGSH---EFTCIAKNEYGQ---TTVEIPVEI 4321
Query: 1110 ITRLQNQKV---NKGNKATFE--IEL---TKGDALV--RWFKDGSEIQFSNHIQLTIDGK 1159
+ +N+ + A + ++L +GD + +WF+DG ++ + ++T+D
Sbjct: 4322 GLKTENKLTLVKTLNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKC 4381
Query: 1160 KQKLKIYDCDLDDAGE--YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
L++ L++ G +CEV NS + ++ T + +F++ N+ +L
Sbjct: 4382 ISTLQL---KLEETGTRIITCEVSNSSSKVNASCNVERVHNT--VSDFVMTNDNSTRFLA 4436
Query: 1218 V 1218
V
Sbjct: 4437 V 4437
Score = 44.8 bits (101), Expect = 7e-04
Identities = 47/213 (22%), Positives = 84/213 (39%), Gaps = 23/213 (10%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP+ I+ +K+ V +++ L +V +P W N K V + H I I +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVG-HGINISR 147
Query: 794 PKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENA-----------------EPPLF 835
K + ++GVY N G++ + ITV E + + P F
Sbjct: 148 LKVSRPEQGVYKCVTRNPAGVSTSYGYITVNADREHLSSSKEDMRLQRQHSVTYHQAPRF 207
Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
+ + + V + + V NP +W+ N + S + F ++ +
Sbjct: 208 LTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMF-SPDVNRSVVRF 266
Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
+ +G+YK VASN G + V D++KV
Sbjct: 267 SIPV-AGEYKVVASNVHGSAMSCGHV--DIQKV 296
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/180 (21%), Positives = 71/180 (39%), Gaps = 9/180 (5%)
Query: 1023 LQDFEVKEKDVAILEVEINS---ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
+ + VK + A + E+N+ + + W I ++D + L IR+
Sbjct: 2911 IPSYVVKLESTATITCELNNYLPKNCTIDWYCGKTKIIIDHEQFDRISHDLLEVLIIRSV 2970
Query: 1080 SVHDEGEYSCILRDESCTAEVTVVE-----LPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
+ YS + ++ +VE I+TR + Q V +G +EL +
Sbjct: 2971 EAINGNLYSLKINEDLFPVAYLIVENTNLTTSANILTRPETQFVMEGQPTVITVELDDPN 3030
Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGK-KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
+V W KD + + I+L DG+ ++ I + + D G Y + L VEE
Sbjct: 3031 VIVNWLKDRRPLHENERIRLETDGQGNHRVIIPNTCVGDQGTYLALTSSESVAITLVVEE 3090
Score = 43.2 bits (97), Expect = 0.002
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVN---EVDISDASE 1466
TI + + +++ + E IS+K N+ N+ + A N +V+ S
Sbjct: 3819 TISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVETSCEIV 3878
Query: 1467 TTEYYKVIKETKIQS---PTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
+ VI ++ I S P PL + +T N+ I + C F G P P W +DG L
Sbjct: 3879 AADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLL 3938
Query: 1523 KTAK---ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
K T + Y C N+ G TSC + +
Sbjct: 3939 DLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDV 3986
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
E+ E + P F H + T++ + G+P P + W+ ++ SQ+ M
Sbjct: 1124 EEDNQIEATQEPRFETSTDEYHVKENGTIKMAATISGHPTPFLEWYFGEEKLQVSQNVSM 1183
Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
YY + + ++++ V G + A N G + +L V+
Sbjct: 1184 YY-EAGTSAIILKNVQKRQGGNYFLRAHNCHGESILPMKLTVD 1225
Score = 42.3 bits (95), Expect = 0.004
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 1780 DNESVYITW-FPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
+ E+V +TW P+E NG S + +Y VE K +G +W+ A + L T Y F
Sbjct: 10451 ERETVTLTWSLPTELNG-SNVNEYLVERKTVDGGRWRHACTVTDSRAVVDGLFSGTEYVF 10509
Query: 1838 RIYARNEIGTSLP 1850
R+ A N G S P
Sbjct: 10510 RVVAVNGAGQSAP 10522
Score = 39.1 bits (87), Expect = 0.034
Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 10/198 (5%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRX-XX 1535
Q+P + L N E ++L C+ G+PQP++ W DG + YE+
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
Y C A N G + C + + + + + K+ D L T
Sbjct: 1737 RIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDDAVDLLRQLSEIKIIDPTLSTGY 1796
Query: 1596 -IEGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTAG 1652
+ I E ++ N L DKE IT + R + +R S++ T++ +
Sbjct: 1797 PMSMISDEENTSHQLLSNVLLTDKEVPITATYNEDLSRAESFRRFFESAETTVKVTELYQ 1856
Query: 1653 TSSVEVTLKVYDKPSKPE 1670
SVE + +P K E
Sbjct: 1857 GESVEAQ---FQQPEKRE 1871
Score = 39.1 bits (87), Expect = 0.034
Identities = 43/225 (19%), Positives = 86/225 (38%), Gaps = 22/225 (9%)
Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWF 1140
+DE E S I D + + + P RL + +K T E+ + + W
Sbjct: 3765 YDEDECSTIA-DTITSLSSSPLYTAPVFTERLPSSACFANSKLTLEVMFSGVPQPTISWL 3823
Query: 1141 KDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILT--- 1190
D E + I + + ++ ++ D + G C N + C +
Sbjct: 3824 IDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVETSCEIVAADEI 3883
Query: 1191 --VEEPSI------NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF 1242
+ + SI +F + LPE + N + + + L ++K V+ D +K+
Sbjct: 3884 SVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKY 3943
Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK--STTKLKVEVVE 1285
+ ++ L I + DD+ YTC + + +T ++VV+
Sbjct: 3944 QVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDVVD 3988
Score = 38.7 bits (86), Expect = 0.045
Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
+ P+ + L + R GE V L + G P+P I W + P+ S + IL
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 793 KPKK--VKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
+ + ++DEG Y A N G + + + E ++
Sbjct: 1737 RIESTLIEDEGEYCCTASNVAGTTFSKCYLKLSEADDD 1774
Score = 38.3 bits (85), Expect = 0.059
Identities = 38/174 (21%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798
++ V +G+ +++ ++ +P + W K+ +P+ + + ++DG + I+ V
Sbjct: 3010 ETQFVMEGQPTVITVEL-DDPNVIVNWLKDRRPLHENERIRLETDGQGNHRVIIPNTCVG 3068
Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR------FQEITVKEKGTIKL 852
D+G Y L +SE +A T + VEE EE + QE V T +
Sbjct: 3069 DQGTY-LALTSSESVAIT---LVVEERIEEKEVMVIASGTESEEDDVQEYLVPPGSTATI 3124
Query: 853 VARVTRNPVP-SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
+ + SI W R+ + I + T++ ++ + + +DSG YK
Sbjct: 3125 ACELEECELKRSIRWLRDGKDIRFEQGKTEHVQNGLKHYLVVHDATSLDSGLYK 3178
Score = 37.9 bits (84), Expect = 0.078
Identities = 20/71 (28%), Positives = 34/71 (47%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
+ A I G P P + WY KL+ + ++ + TS I +K +++ Y + A N
Sbjct: 1154 MAATISGHPTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCH 1213
Query: 1652 GTSSVEVTLKV 1662
G S + + L V
Sbjct: 1214 GESILPMKLTV 1224
Score = 37.1 bits (82), Expect = 0.14
Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 19/217 (8%)
Query: 1187 AILTVEEPSINFTLRL---PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
A L VE ++ + + PE V +TVE+ D + V W K + + + E+
Sbjct: 2990 AYLIVENTNLTTSANILTRPETQFVMEGQPTVITVELDDPNVIVNWLKDRRPLHENERIR 3049
Query: 1244 LISDVK--KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV---------D 1292
L +D + R +I C D ++ + T + E +E +V D
Sbjct: 3050 LETDGQGNHRVIIPNTCVGDQGTYLALTSSESVAITLVVEERIEEKEVMVIASGTESEED 3109
Query: 1293 YEREYRIKRGSDVTLLVDYQAFP-QPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKV 1350
+EY + GS T+ + + + + W+ + K I+ + T+ + L +
Sbjct: 3110 DVQEYLVPPGSTATIACELEECELKRSIRWLRDGKDIRFEQGKTEHVQNGLKHYLVVHDA 3169
Query: 1351 ENTDAGIYKL-RLENNCGHADVEMNV--TILDKPSPP 1384
+ D+G+YK R E C + V TI + S P
Sbjct: 3170 TSLDSGLYKTERSEEQCEETIIPRGVVATIQCQTSEP 3206
Score = 36.7 bits (81), Expect = 0.18
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 3/114 (2%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
EPP+ + L S+I V E ++LS V P W N VK + D H+ +
Sbjct: 404 EPPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKKSQSVVLLDEHNKST 463
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA--EPPLFINRFQEIT 843
L +G Y + A N G + +T ++ A EPP + +T
Sbjct: 464 LVLHPPVKQGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVT 517
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 806 KAENSEGIA-ETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVP 862
+ +N +GI E ++ TE +A P P F+ + + ++L + P P
Sbjct: 1649 EGDNRQGIEDEPFTEVSQSLATESSAAPQAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQP 1708
Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
I W + + I P++ + ++ L I + E D G+Y C ASN AG
Sbjct: 1709 EIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIE-DEGEYCCTASNVAG 1758
Score = 36.3 bits (80), Expect = 0.24
Identities = 44/194 (22%), Positives = 79/194 (40%), Gaps = 22/194 (11%)
Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
+E L C+ G+P V W DG + + +E+ +C A
Sbjct: 4052 DEKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALLRMKNIKKDKSVVQCEA 4111
Query: 1553 FNDHGEVETSCVV---GIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
N G+V TSCV+ G++ QKP +S +K D + ++ G P P
Sbjct: 4112 INCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLS---LKDTCTTTDHATLKCIVVGTPLP 4168
Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+V NG +N K I +++ +I++ ++ SN G+S+ +K+
Sbjct: 4169 DVSCSFNG-VTDNSK---IRSEDGIVLIQVNDV-TEEGIVVECTISNETGSSTSNCVVKI 4223
Query: 1663 YDKPSKP-EGPVIM 1675
+ K + P+I+
Sbjct: 4224 IKQEEKNYQRPIIV 4237
Score = 35.9 bits (79), Expect = 0.32
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 3/137 (2%)
Query: 1287 PPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
PPK V + + L VD QA P W VN +KK + +D + S
Sbjct: 405 PPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKK-SQSVVLLDEHNKS- 462
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
T+ G YK+ N+ G V VT + + +I S++ + E
Sbjct: 463 TLVLHPPVKQGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVTCSHEE 522
Query: 1406 NTGNSTIIYYVVEYQEI 1422
+ G+ + + V QE+
Sbjct: 523 DVGSHSSLQTVRRIQEM 539
Score = 35.5 bits (78), Expect = 0.42
Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Query: 1091 LRDESCTAEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSE 1145
+RD+ + E+ LP P+I+ L + G + ++T A V W KD
Sbjct: 801 IRDDDSSFEIVPPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVN 860
Query: 1146 IQ---FSNHIQLTI-DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
++ + + T+ DG +L +C +DAG Y C N TA
Sbjct: 861 VEDWVLNKDVTTTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTA 906
Score = 35.5 bits (78), Expect = 0.42
Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 510 PIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
P+ + KL +P G + ++ G P P++ + +++Y DN+A+L
Sbjct: 8836 PVILNKLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIY---DNIASL 8892
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEM 611
I ++ D G +T V +N G S + +V+ PL +++
Sbjct: 8893 YIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKPRKAQL 8936
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PPK + + YR+ ++L+V+ + P EW N K + + + +++
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQV--GHGINIS 146
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
KV + G+YK N G
Sbjct: 147 RLKVSRPEQGVYKCVTRNPAG 167
Score = 33.9 bits (74), Expect = 1.3
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 633 PPTF-SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP F + P V+ ++L + AIP + AW G E+ +++ + D H
Sbjct: 405 PPKFVTTLPSVITVNAEEKLVLSVDVQAIPAAEFAWHVNGFEVKKSQSV---VLLDEHNK 461
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGE-KEPPQVIEPLKSMIV 746
+++ VK +G Y V A N G S+ + ++K G EPP ++E ++
Sbjct: 462 STLVLHPPVK---QGKYKVTARNDVGSDSVTTQVTRIGEVKDGAGSEPPDIVESAVTVTC 518
Query: 747 RQGESV 752
E V
Sbjct: 519 SHEEDV 524
Score = 33.9 bits (74), Expect = 1.3
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1017 PEFIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
P+F+RKL + F + V + + ++ W DG+ I P ++Y + L
Sbjct: 1679 PKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPN-DEYSIVYEDGVCILR 1737
Query: 1076 IRNTSVHDEGEYSC 1089
I +T + DEGEY C
Sbjct: 1738 IESTLIEDEGEYCC 1751
Score = 33.1 bits (72), Expect = 2.2
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 11/135 (8%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
+ A + + P V W K+G + EN+K + + ++ I+ S YT A +
Sbjct: 964 MVATVRSVAPITVSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESE 1023
Query: 1651 AGTSS----VEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGLELTKYA-I 1703
G S+ VE+T+ P E I E+ + + + L + E++ A I
Sbjct: 1024 HGVSNSSCQVELTISAESSPESFEKVEITPPEEVKETGIDDDIEVILKE---EVSGTAQI 1080
Query: 1704 EKHEPDNNRWIKVAD 1718
EK E + +KVAD
Sbjct: 1081 EKREEEFKLLVKVAD 1095
Score = 32.3 bits (70), Expect = 3.9
Identities = 42/190 (22%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 1345 LTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
LTI+ N D+G+Y E+ G ++ ++ +TI + SP + EI +
Sbjct: 1003 LTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELTISAESSPESFEKV-EITPP------E 1055
Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWIS-----VKNITKTQTSIQN-LKTNSSYRFRAYAV 1456
E + TG I +++ +E+ T I K + K + + L N AV
Sbjct: 1056 EVKETGIDDDIEVILK-EEVSGTAQIEKREEEFKLLVKVADQVASTLVANVFLEAVHEAV 1114
Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
++ ++ E + +E + ++ T E +K N I++ G P P + WY
Sbjct: 1115 KKIVETEDEEEDNQIEATQEPRFETSTDEYHVKE-----NGTIKMAATISGHPTPFLEWY 1169
Query: 1517 RDGKKLKTAK 1526
+KL+ ++
Sbjct: 1170 FGEEKLQVSQ 1179
Score = 32.3 bits (70), Expect = 3.9
Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 9/101 (8%)
Query: 149 ERVTLEKSDLFDSQEDESKPDV-SQPPQNII--EEAKSEPKLIEESEQPIAKTSEIDNEV 205
E V E++ +QED K S+P Q + E A SEP ++ + A + I EV
Sbjct: 3565 EDVPKEEAPSEPTQEDVPKEAAPSEPTQENVPKEAAPSEPT--KDVPKEAAPSEPIQEEV 3622
Query: 206 PEKINVPDDKETSQTPTSFNKRSK-LTPIKIERKEMEVSTP 245
P++ + E +Q + +KRS+ + P +I++ E TP
Sbjct: 3623 PKEATL---SEPTQEQSEVSKRSEPVEPTQIQQAASEEETP 3660
Score = 31.5 bits (68), Expect = 6.8
Identities = 29/135 (21%), Positives = 52/135 (38%), Gaps = 6/135 (4%)
Query: 782 SDGDTHSIT--ILKPKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR 838
SDGDT + + PKK + DE V + + EN E ++ T + I
Sbjct: 8693 SDGDTQEVEQKVTLPKKHQSDEDVISKEEENLETSVSYGSIEETVSFTIGTGQS--IIEH 8750
Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
+ V + + ++ T P+ W+ N ++ P E + G L + +
Sbjct: 8751 PKSHAVGQMNSEVIIKCKTSQPISDAKWFCNGMVLLPDEQVNMTVTGCEAVLRLVKFLPQ 8810
Query: 899 IDSGDYKCVASNSAG 913
+ G+Y + S G
Sbjct: 8811 -NKGNYHVLIDGSIG 8824
Score = 31.1 bits (67), Expect = 9.0
Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS-QDFQMYYDDDNVAT 567
AP F+ ++ GS V + +V+ P + +WF + S +M+ D N +
Sbjct: 204 APRFLTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMFSPDVNRS- 262
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
V+R P AG + VA N G A S + ++ + S +T
Sbjct: 263 -VVRFSIPV-AGEYKVVASNVHGSAMSCGHVDIQKVIELEESTLT 305
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/81 (19%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 1303 SDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
S +TL V + PQP W+++ +++ + ++ +++ V+ G K R
Sbjct: 3804 SKLTLEVMFSGVPQPTISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCR 3863
Query: 1362 LENNCGHADVEMNVTILDKPS 1382
N G + + D+ S
Sbjct: 3864 ATNCAGQVETSCEIVAADEIS 3884
>AF106579-3|AAM45364.1| 4369|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform d protein.
Length = 4369
Score = 87.0 bits (206), Expect = 1e-16
Identities = 83/305 (27%), Positives = 130/305 (42%), Gaps = 22/305 (7%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT S++ K + G + WL G+EI +
Sbjct: 4070 PPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTN---- 4125
Query: 693 SVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
S L I ++ G YTV N G E+ + + T + + P L + ++Q
Sbjct: 4126 SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNG 4185
Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
S Q+ G P+PTI W K+ +P+ +G + + D G+Y + A
Sbjct: 4186 PAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIIST-DAGIYEIVA 4244
Query: 808 ENSEGIAETSAVITVE-EPTEENAEP------PLFINRFQEITVKEKGTIKLVARVTRNP 860
+N G A A + V + T + AE P F ++ Q I V E + A+ + P
Sbjct: 4245 KNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFP 4304
Query: 861 VPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
P+I WYRNNE + ++ I+Q+ GE I L I+ +E D +YK ASN AGK+S
Sbjct: 4305 DPTIRWYRNNEPVKHADGYEISQS-KGEAI-LRISAARNE-DVAEYKVEASNPAGKASSV 4361
Query: 919 ARVTI 923
A + +
Sbjct: 4362 ANLVL 4366
Score = 84.6 bits (200), Expect = 7e-16
Identities = 83/332 (25%), Positives = 131/332 (39%), Gaps = 41/332 (12%)
Query: 500 KPTSEEQSMA--PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
+PT QS P ++L+P G +F + G ++TW + IK +
Sbjct: 4059 QPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTL 4118
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
+ N ++L I + AG +T +NAAG S L V P +
Sbjct: 4119 ITTTPTN-SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTT------------ 4165
Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
+G P FS + + + C++ P+P I W G+ + D
Sbjct: 4166 ------------QGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPND 4213
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI---KTGEK-- 732
+ V E + LK +N+ G Y +VA N GEA L + KTG+
Sbjct: 4214 DRFQVVEEGGAYK----LKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAE 4269
Query: 733 -----EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
E P+ ++ ++V +G+ SAQ G P PTI W +NN+PVK +
Sbjct: 4270 EGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSK 4329
Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
IL+ ++E V K E S + S+V
Sbjct: 4330 GEAILRISAARNEDVAEYKVEASNPAGKASSV 4361
Score = 84.2 bits (199), Expect = 9e-16
Identities = 64/272 (23%), Positives = 121/272 (44%), Gaps = 18/272 (6%)
Query: 722 PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
P KI ++ PP + + LK + G++ + G +TW K+ K +K+
Sbjct: 4058 PQPTKIGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRT 4117
Query: 782 SDGDTHSITILKPKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
T + + L ++++ G YT++ EN+ G E+ A +TV PT + P F R
Sbjct: 4118 LITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPD-FSARL 4176
Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
++ +++ G + ++ P P+I W+++ + + + +G +L +N+ S
Sbjct: 4177 NDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIIS-T 4235
Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE------------TEEGKTVI 947
D+G Y+ VA N G++ AR+ ++++K YE +EGK
Sbjct: 4236 DAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQ 4295
Query: 948 LECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977
Q S + +WY N + + D EI Q
Sbjct: 4296 FSAQFSGFPDPTIRWYRNNEPVKHADGYEISQ 4327
Score = 76.6 bits (180), Expect = 2e-13
Identities = 53/195 (27%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSI 789
PPQ + +S+ + E+V SA+VVG P P++TW K++ V ++ D
Sbjct: 304 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGR 363
Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
I++ D +Y L A N G ++ + V + ++ E P F +FQ T+ + +
Sbjct: 364 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQ--AKSPEAPEFTGKFQSTTLYDGDS 421
Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
+KL + V S W+++NE IS + + G L I N + + G Y+C A+
Sbjct: 422 VKLYCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMK-EGGWYRCDAT 479
Query: 910 NSAGKSSHGARVTID 924
N G ++ RV ++
Sbjct: 480 NKHGTTTLKGRVVVN 494
Score = 66.1 bits (154), Expect = 3e-10
Identities = 119/539 (22%), Positives = 206/539 (38%), Gaps = 81/539 (15%)
Query: 474 LMDENNYTQYLQKKLN-EKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFEC 531
L+ + ++ LQK E IDK + P E + P +V+ ++ +G TV
Sbjct: 2351 LLLDTSHPASLQKIQELEAIDKYARLDAPEREYEK--PQWVQGFENYENVGEGQTVTLHG 2408
Query: 532 QVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
VE G P ++ W ++ + F+ Y+ N A L I V P D+G +TC A N
Sbjct: 2409 LVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN-AILTIVHVLPHDSGVYTCRAWNTQ 2467
Query: 590 GFASSTTELIV---EAPLSDHGSEMT---VXXXXXXXXXXXXADILEGIPPTF-SKKPKA 642
G AS++ + E L D ++ + +I++ P F ++ A
Sbjct: 2468 GEASTSATVTTAGYEKILYDSQHPVSWERIQELEAPKIVEEIEEIVQKEKPNFLTQLESA 2527
Query: 643 QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDE-----------NISVAIESDMH 689
+ V EG + LE +P+ + W G+ + + + ++ ++ H
Sbjct: 2528 ENVPEGVPLHLESTFQPARDPELKVVWQKNGQPLGASQLVQTKHELGWATLDISSANEDH 2587
Query: 690 MYCSVLKITNVKKFQ--------EGTYTVVAVNREGEASLPIVLKIKTGEKEP------- 734
L ITN + GT ++ R E+ I + E EP
Sbjct: 2588 NGVYTLTITNSEGEAVSTASIRVAGTGPILGNTRHEESWKRIQILEAPKEAEPEAPAPVY 2647
Query: 735 --PQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
P + + +G+ V A + V +PR + W +N P+ + I
Sbjct: 2648 DHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQVQWIRNGVPLAHGSKYAIQQDFGIC 2707
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVI----------------------TVEEPT 826
L +DEGVY L+ N EG A +SA + +E P
Sbjct: 2708 TLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCHGKDAILGDVQHQESWKRIQEIEAPK 2767
Query: 827 EENAE-------PPLFINRFQ---EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
++ E PP FI + + + + +P +I W+ N E +S S
Sbjct: 2768 QKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSAS 2827
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
+ D + + I + DSG++KCVA N+AG++ A + + ++V LQ
Sbjct: 2828 SRVKMINDFGWVIMDIAQTEPR-DSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQ 2885
Score = 64.1 bits (149), Expect = 1e-09
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 23/248 (9%)
Query: 500 KPTSEEQS-MAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQ 554
KP+ ++ + P+F ++L P +G +V +C V+ P +I WF +
Sbjct: 1581 KPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGS 1640
Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDH- 607
+ +D V L + PED GT+TC A N G +TT++ +E L H
Sbjct: 1641 RIRTIHDFGYVG-LEFLHIHPEDTGTYTCKATNLIG--EATTDIFLECKPRRNIYLDTHH 1697
Query: 608 -GSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD- 664
S + L PPTF++ + EG I LECRL+ + +P
Sbjct: 1698 ESSWQKIQEIENRVDEREPTPELTFQPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTM 1757
Query: 665 -IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
+ W G+ + A D Y + L I + G YT AV+ GEA+
Sbjct: 1758 RVTWTRNGQPLPEASRFMPARNFD---YVN-LDILALYGEDSGVYTCKAVSAFGEAATSC 1813
Query: 724 VLKIKTGE 731
+K G+
Sbjct: 1814 TVKCAAGK 1821
Score = 63.3 bits (147), Expect = 2e-09
Identities = 78/409 (19%), Positives = 161/409 (39%), Gaps = 29/409 (7%)
Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP-QPNDEWIVNSKIIK 1329
LD + ++K++ + P + D E ++K ++ + + Q P QP +E IV+ ++
Sbjct: 3956 LDVPARDQVKLKTAK-PTRGKDLEAGEKVKLKTEKAKIKEIQQKPEQPKEEPIVHKDAVQ 4014
Query: 1330 KCKHTKPSIDSKSASLTI---KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
P K T+ K ++ T A + + E + + + P
Sbjct: 4015 LKTQQLPKTGIKGDHFTVDREKDLKETPAVVKPVIEETRISNKPQPTKIGQSKQAPPTIS 4074
Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
+ + E G + + + ++ + +EI +T + ++ T T +S+ +
Sbjct: 4075 QQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKST-FRTLITTTPTNSSLHIGRL 4133
Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKET-KIQSPTVEKPLKNITTEPNEDIELTCI 1504
+S+ Y V + + E+ V T + ++P L ++ + N E +C
Sbjct: 4134 ENSHAGE-YTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQ 4192
Query: 1505 FGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVE 1560
GG P+P + W++DG+ L + E Y+ +A N GE
Sbjct: 4193 IGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEAR 4252
Query: 1561 TSCVVGIQ--------------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
+ + + P T + I G ++ +A G P P + W
Sbjct: 4253 CKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQF--SAQFSGFPDPTIRW 4310
Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
Y+N +++ Y I+ + +++RI + ++Y +EASN AG +S
Sbjct: 4311 YRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKAS 4359
Score = 62.1 bits (144), Expect = 4e-09
Identities = 83/338 (24%), Positives = 135/338 (39%), Gaps = 32/338 (9%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
P F L P +G ECQV PR I WF + + + +D V
Sbjct: 3183 PKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIHDFGFVV 3242
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---------PLSDHGSEMT-VXXX 616
L + P+D+GT+TC A N G +TEL V ++ +T +
Sbjct: 3243 -LQLTPAEPQDSGTWTCRATNQHGSDEVSTELKVVGGGGVSYEWQSTAERKERITELEDW 3301
Query: 617 XXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
++ P+FS+ ++E C L I +P + W G
Sbjct: 3302 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHP 3361
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK- 732
I IS E + + L I ++ G Y VA N +G A+ + +++ +
Sbjct: 3362 IPYSNRISCTNEFGV----ATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQI 3417
Query: 733 EPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDG 784
+ PQV++ L + + +G+S+ L +V + +PR + W +N P+ + PT G
Sbjct: 3418 DAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFG 3477
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S+ IL +D G Y L N +G A + ITV
Sbjct: 3478 FV-SLDILYAYP-EDNGDYELVVRNDKGEARSKTKITV 3513
Score = 61.7 bits (143), Expect = 6e-09
Identities = 69/300 (23%), Positives = 113/300 (37%), Gaps = 27/300 (9%)
Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
+ PP I +L+ + G A F IE + V W KDG EI+ + +T
Sbjct: 4068 QAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTNSS 4127
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCT----AILTVEEPSI-----NFTLRLPEFILVPANTD 1213
L I + AGEY+ + N+ T A LTV P+ +F+ RL + + + N
Sbjct: 4128 LHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLND-LRIQQNGP 4186
Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271
A + +I E + W+K + + ++F ++ + L D Y V
Sbjct: 4187 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4246
Query: 1272 ---DAKSTTKLKVEVV-------EFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
+A+ +L V + E P P+ + + G + FP P
Sbjct: 4247 GVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDP 4306
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
W N++ +K + S A L I N D YK+ N G A N+ +
Sbjct: 4307 TIRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVL 4366
Score = 60.1 bits (139), Expect = 2e-08
Identities = 57/222 (25%), Positives = 91/222 (40%), Gaps = 17/222 (7%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F K + DG +V+ C+ G WF+ I + + + N TL
Sbjct: 404 APEFTGKFQSTTLYDGDSVKLYCKAAG-EGVSFKWFKDNEPISSGGSYAVD-NKGNETTL 461
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS---EM-TVXXXXXXXXXXX 624
I ++ G + C A N G + ++V + +G EM T+
Sbjct: 462 HINNATMKEGGWYRCDATNKHGTTTLKGRVVVNSRQKFNGPAHREMITLRKVDKVERSRT 521
Query: 625 XADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPD 677
+ L+ + P F ++Q + EG LE + + +P+ IAWL G+ I+
Sbjct: 522 PVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILAS 581
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I + + + L+I V F +G YTVVAVN GEA
Sbjct: 582 SRIVTFTDFGI----AALEINPVNVFDQGEYTVVAVNPLGEA 619
Score = 55.6 bits (128), Expect = 4e-07
Identities = 51/192 (26%), Positives = 81/192 (42%), Gaps = 15/192 (7%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDG 885
NA PP F+ Q + K T+ A+V P PS+TW +++ + S I DG
Sbjct: 301 NARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDG 360
Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV------EKVTFVKHLQKSYE 939
L+I VD+ D+ Y VA N G S +R +++V E F Q S
Sbjct: 361 SG-RLIIEKVDAH-DADMYMLVARNDGG--SFQSRFSLNVLQAKSPEAPEFTGKFQ-STT 415
Query: 940 TEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
+G +V L C+ + VS KW+ + + IS + +G + G +
Sbjct: 416 LYDGDSVKLYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYR 475
Query: 999 CIVKDQETSTML 1010
C ++ +T L
Sbjct: 476 CDATNKHGTTTL 487
Score = 54.8 bits (126), Expect = 6e-07
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
+Q AP F LR + +FEC V GYPRP++TWF F++ +D +
Sbjct: 3692 KQKQAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLH 3751
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
T+ + DAG +A+N G ST L
Sbjct: 3752 YLTVSKSRI--SDAGEVVAIARNTEGETISTATL 3783
Score = 54.8 bits (126), Expect = 6e-07
Identities = 53/230 (23%), Positives = 90/230 (39%), Gaps = 19/230 (8%)
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
+ E IS+ + T+ I ++K PT+ + LK + E + + F G KVTW
Sbjct: 4049 IEETRISNKPQPTK----IGQSKQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTW 4104
Query: 1516 YRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
+DGK++K T T Y N G VE+ + +
Sbjct: 4105 LKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPT 4164
Query: 1569 ---QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
+ P + D++ + E+ + I G P P + W+K+G L ND + + +
Sbjct: 4165 TQGKAPDFSARLNDLRIQQNGPAEF--SCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEG 4222
Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSK--PEGP 1672
++ + + + Y I A N G + + L V K K EGP
Sbjct: 4223 GAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4272
Score = 53.2 bits (122), Expect = 2e-06
Identities = 56/223 (25%), Positives = 85/223 (38%), Gaps = 17/223 (7%)
Query: 510 PIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P F+++L P + FE VE P +T WF + S +M +D
Sbjct: 2781 PRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMI-NDFGWV 2839
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTT-------ELIVEAPLSDHGSEMTVXXXXXX 619
+ I + P D+G + CVAKNAAG A ST E+I++ L +
Sbjct: 2840 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEAGK 2899
Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVPD 677
D P + ++EG L+ + + +P I WL G+ I
Sbjct: 2900 PAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHS 2959
Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
+ + +VL I ++ K G YT N GEAS
Sbjct: 2960 NRYKMVHDFGF----AVLDILHLLKHDAGEYTFRVSNNSGEAS 2998
Score = 52.8 bits (121), Expect = 3e-06
Identities = 59/241 (24%), Positives = 93/241 (38%), Gaps = 17/241 (7%)
Query: 491 KIDKLPVFEKPTSEEQSMA-----PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITW 543
K+DK+ P ++ Q ++ P F L+ + +G + + E + P +I W
Sbjct: 512 KVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAW 571
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
I S + + D +A L I V D G +T VA N G A + + V
Sbjct: 572 LLNGKGILASSRI-VTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGEARVSANIAVIGH 630
Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIP---PTFSKKPKAQYVDEGSDILLECRLVAI 660
S + + A G P F ++Q V EG I LE +L I
Sbjct: 631 GSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKLTPI 690
Query: 661 PEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+PD + WL G E+ ++ + H + S L I G Y+ A N+ GE
Sbjct: 691 NDPDLRVVWLLDGNELPSNDKYRQTLS---HGFAS-LDIPQTSSNDSGLYSCRAFNKLGE 746
Query: 719 A 719
+
Sbjct: 747 S 747
Score = 52.0 bits (119), Expect = 5e-06
Identities = 64/265 (24%), Positives = 102/265 (38%), Gaps = 22/265 (8%)
Query: 470 PAQYLMDENNYTQYLQK-KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGST 526
PA ++ + + + L K E ++K E Q P FV L+ +G
Sbjct: 1154 PAGQILSDTQHQESLGKINYLENLNKYGRVEIEDKGPQE-PPTFVVPLQADLGDVEEGEP 1212
Query: 527 VQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
+ ECQV +I W R + F+ +YD V+ L I + +DAGT+TC
Sbjct: 1213 IHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFYDFGFVS-LDILGFYAQDAGTYTCR 1271
Query: 585 AKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
A+N+ G A + + + + S + L PP F K
Sbjct: 1272 AENSLGQAETVATIRCAPKDAILGAVQHPRSYARIQEIEAPKPAPQEVPDLPHQPPAFVK 1331
Query: 639 K--PKAQYVDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSV 694
+ P Q + EG ++ LE ++ + + WL G+ ++ + D
Sbjct: 1332 QLGPAIQCM-EGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRF--VLSQDFGYI--A 1386
Query: 695 LKITNVKKFQEGTYTVVAVNREGEA 719
L I GTYT+V NR GEA
Sbjct: 1387 LNILYCYPEDNGTYTLVVRNRAGEA 1411
Score = 52.0 bits (119), Expect = 5e-06
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F +++P +G QF Q G+P P I W+R +K + +++ A L
Sbjct: 4276 APRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEI-SQSKGEAIL 4334
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
I ED + A N AG ASS L++
Sbjct: 4335 RISAARNEDVAEYKVEASNPAGKASSVANLVL 4366
Score = 51.6 bits (118), Expect = 6e-06
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 1191 VEEPSINFTLRLPEF-ILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISD 1247
V+ P+ +F+ L + L A+ A++ V P D TL V W I + + + ++
Sbjct: 3314 VDYPAPSFSQGLTDLGQLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNE 3373
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP-----PKIVDY--EREYRI 1299
TL+I+ D EY CV + K S T + VE P++V + I
Sbjct: 3374 FGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENI 3433
Query: 1300 KRGSDVTLLVDYQAFPQP--NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
G + L P + EW+ N + + KP+ + SL I D G
Sbjct: 3434 LEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFVSLDILYAYPEDNGD 3493
Query: 1358 YKLRLENNCGHADVEMNVTILDKPS 1382
Y+L + N+ G A + +T+L +PS
Sbjct: 3494 YELVVRNDKGEARSKTKITVLPRPS 3518
Score = 50.8 bits (116), Expect = 1e-05
Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 23/273 (8%)
Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR-PKHTPDGSTVQFECQ 532
L +N + L + + + P E+ E + P+F+E L P T +G F +
Sbjct: 3013 LQPQNEQKAKAVEILEDNLRRRP--EEIEQELKEATPVFIEPLSAPVETEEGGRAHFTAR 3070
Query: 533 VEGYP--RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
E + Q+ W+ +K + + L I +PED G + C A N G
Sbjct: 3071 YEPVNDNQLQVQWYHDGRPLKNGSRIKTI-NSFGYVVLEISPTYPEDNGEYICRAVNRVG 3129
Query: 591 FASSTTEL-------IVEA---PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKK 639
A ++T+L I+ A P + + A + PP F S
Sbjct: 3130 EAVTSTKLTCTPKEGIISATQLPERMANAGRRIAEIEAPRPAREDAPDADHGPPKFTSAL 3189
Query: 640 PKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
+ EG LEC++ + +P I W G+ + N + +++ VL++
Sbjct: 3190 AGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPV----NHTNRMKAIHDFGFVVLQL 3245
Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730
T + GT+T A N+ G + LK+ G
Sbjct: 3246 TPAEPQDSGTWTCRATNQHGSDEVSTELKVVGG 3278
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816
+G+P + W N P+ S + + L K + D G Y A N +G A +
Sbjct: 3346 IGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATS 3405
Query: 817 SAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVT--RNPVPSITWYRNNEII 873
I VE T+ +A P + + + E +I L RVT +P + W RN +
Sbjct: 3406 VGKIAVESSTQIDA-PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPL 3464
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ F+ + L I E D+GDY+ V N G++ ++T+
Sbjct: 3465 PEASRFKPTFEFGFVSLDILYAYPE-DNGDYELVVRNDKGEARSKTKITV 3513
Score = 48.4 bits (110), Expect = 6e-05
Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 20/243 (8%)
Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
E+P AP F +L K + V FE ++ + + W+ + +
Sbjct: 916 ERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAAHR 975
Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP----LSDHGSE- 610
F +D VA L + +P+D+GT+T VA+N G A S EL+V L H E
Sbjct: 976 FHPMFDFGYVA-LDLLYAYPQDSGTYTLVARNELGEARSNVELVVGTEKVLYLEPHHPEG 1034
Query: 611 MTVXXXXXXXXXXXXADI----LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD-- 664
+ A++ + P + P Q ++E +I ++ R + +P
Sbjct: 1035 LERIKELEQDRRQGIAEVEDRTCDAAPKFLNDLPDIQ-LNEHENIHVDLRATPVNDPTMV 1093
Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
I W G ++ + E L I GTY+V A N GEA V
Sbjct: 1094 IEWFVNGRPLLTGSRVKTLNEFGF----IALDIKGAIAEDSGTYSVRASNLLGEAIRQCV 1149
Query: 725 LKI 727
+ +
Sbjct: 1150 ITV 1152
Score = 46.4 bits (105), Expect = 2e-04
Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 506 QSMAPIFVEKLRPKHTPDG-STVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDD 562
Q + P F+ +++P H FE +++ P +++W + + + Q++ +
Sbjct: 785 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPLPNANRIQIF-QN 843
Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
V +L + +PEDAG +TCV N+ G A S+ EL
Sbjct: 844 FGVVSLSLHPTYPEDAGVYTCVLFNSHGQAQSSAEL 879
Score = 46.0 bits (104), Expect = 3e-04
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 11/157 (7%)
Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQVV--GNPRPTITWCKNNKPVKA---LPTKSDGDT 786
E P ++PL+S+ + +G +L A++V +P + W N++P+ + T +D
Sbjct: 2251 EKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMESNWISTSNDFGC 2310
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITV 844
S+ I P + GVY+ KA N G A TSA + V+ E + P + + QE+
Sbjct: 2311 VSLRIA-PVYARHTGVYSCKAWNDSGNAVTSANVGVQGSEGLLLDTSHPASLQKIQELEA 2369
Query: 845 KEKGTIKLVARVTRNPVPS-ITWYRNNEIISPSETIT 880
+K +L A P + + N E + +T+T
Sbjct: 2370 IDK-YARLDAPEREYEKPQWVQGFENYENVGEGQTVT 2405
Score = 46.0 bits (104), Expect = 3e-04
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L+++NVKK + Y + +G A P +K+ PQ PL+++ V + +
Sbjct: 3668 LRVSNVKKDNKNIYW----SEQGGAVQP-------KQKQAPQFTIPLRNLQVTENQPARF 3716
Query: 755 SAQVVGNPRPTITWCKN-NKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENSEG 812
V G PRP +TW N N+ + K + D H +T+ K ++ D G A N+EG
Sbjct: 3717 ECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSK-SRISDAGEVVAIARNTEG 3775
Query: 813 IAETSAVITV 822
++A + +
Sbjct: 3776 ETISTATLDI 3785
Score = 45.6 bits (103), Expect = 4e-04
Identities = 55/231 (23%), Positives = 89/231 (38%), Gaps = 18/231 (7%)
Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDF 556
EKP +E AP F+E L + + F+ +V + P +I WF+ + S F
Sbjct: 1981 EKPDAEHD--APQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRF 2038
Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMT- 612
++ D ++ L I PED+G ++ A NA G A +L V L D E +
Sbjct: 2039 KLTTDFGYIS-LDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTVTGNAVILGDTQHEQSW 2097
Query: 613 ---VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAW 667
D+ G P ++ V EG E + + +P + W
Sbjct: 2098 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 2157
Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
G + + + +D + L+ T + G Y+VV N EGE
Sbjct: 2158 YLNGNPL--SASSRRILRNDFGLVSLDLQYTLGE--DAGEYSVVVKNSEGE 2204
Score = 44.8 bits (101), Expect = 7e-04
Identities = 49/197 (24%), Positives = 84/197 (42%), Gaps = 17/197 (8%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE- 601
W +K S +++ +D +L I + ED+G +T V N+AG A ++ E V+
Sbjct: 1496 WLFNGNPLKASSRYRVL-NDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVDR 1554
Query: 602 --APLSD--HGSEM-TVXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLE 654
+ LSD H + + D PP F+++ + + EG + ++
Sbjct: 1555 LKSILSDTAHPESLRRIREMEQLQPAKPSDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMD 1614
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVV 711
C + I +P I W G ++ I +H + V L+ ++ GTYT
Sbjct: 1615 CVVQPINDPSLRIEWFHDGRPLMFGSRIRT-----IHDFGYVGLEFLHIHPEDTGTYTCK 1669
Query: 712 AVNREGEASLPIVLKIK 728
A N GEA+ I L+ K
Sbjct: 1670 ATNLIGEATTDIFLECK 1686
Score = 44.8 bits (101), Expect = 7e-04
Identities = 63/285 (22%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
K+ P ++L+ + + A +E + V W +DG+ IK +
Sbjct: 4067 KQAPPTISQQLKPLQGELGKAAKFVIEFAGAAPVKVTWLKDGKEIKSTFRTLITTTPTN- 4125
Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE-----LPPEIITRLQNQKVNKGN 1122
L+I GEY+ L + + T E +TV P+ RL + ++ +
Sbjct: 4126 SSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNG 4185
Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
A F ++ + ++WFKDG + + Q+ +G KLK + DAG Y
Sbjct: 4186 PAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAK 4245
Query: 1179 -EVGNSKCTAILTV----------EEP---SINFTLRLPEFILVPANTDAYLTVE---IP 1221
VG ++C A L V E P + FT ++ + I+V A + + P
Sbjct: 4246 NGVGEARCKARLNVNLQKTGKGAEEGPRYEAPRFTSQI-QPIVVDEGKGAQFSAQFSGFP 4304
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
D T + WY+ ++ + + + + L I +D EY
Sbjct: 4305 DPT--IRWYRNNEPVKHADGYEISQSKGEAILRISAARNEDVAEY 4347
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 25/223 (11%)
Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD----VAILEVEINSETADVVWERDGE 1054
I + +E + V P F + L D ++ E D V +LE I T V WE +G
Sbjct: 3302 IHRPKEDLNLPAVDYPAPSFSQGLTDLGQLNEADATAFVCVLE-PIGDPTLRVQWEHNGH 3360
Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELP----- 1106
I P N+ + L I++ D GEY C+ ++ + + VE
Sbjct: 3361 PI-PYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSATSVGKIAVESSTQIDA 3419
Query: 1107 PEIITRLQNQKVN--KGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
P+++ +L + N +G+ E +T D V W ++G+ + ++ + T +
Sbjct: 3420 PQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLPEASRFKPTFEFGFV 3479
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK-----CTAILTVEEPSINFT 1199
L I +D G+Y V N K T I + PS+++T
Sbjct: 3480 SLDILYAYPEDNGDYELVVRNDKGEARSKTKITVLPRPSLDYT 3522
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 5/115 (4%)
Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPK--HTPDGSTVQFECQVEGYPRPQIT--WFR 545
++I+ E +E + AP FV +L +G + E QVE Q+T WF
Sbjct: 1837 QEIENREKLEAVDAEPEKTAPKFVTQLNSSLGELQEGVPIHLEAQVEPTNDNQLTVQWFH 1896
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
+ F+ +D VA L I F +D G + CVA+N+ G A + V
Sbjct: 1897 NGQPLANGHRFRTRHDFGYVA-LDILYAFAQDTGEWACVARNSLGEAQTIANFTV 1950
Score = 43.6 bits (98), Expect = 0.002
Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 24/247 (9%)
Query: 490 EKIDKLPVFEKPTSEEQSMA---PIFVEKLRPKH-TPDGSTVQFECQVEGY--PRPQITW 543
+KI + P EE + P FV +L +G FE Q + P+ + W
Sbjct: 2098 QKIQLIEAPRAPGEEEPDVKHGPPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQW 2157
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-- 601
+ + S ++ +D + +L ++ EDAG ++ V KN+ G ++ +L
Sbjct: 2158 YLNGNPLSASSR-RILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTR 2216
Query: 602 -APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD------EGSDILLE 654
A L D E + EG P + K Q + EGS LLE
Sbjct: 2217 AAILGDTQHEQSWQRIQEIEAPRAPGAEPEG--PVYEKPSFVQPLQSVGDLPEGSVALLE 2274
Query: 655 CRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
RLV + +P+ + W + + ++ IS + + C L+I V G Y+ A
Sbjct: 2275 ARLVPVNDPNLRVQWFYNDQPLMESNWISTSND----FGCVSLRIAPVYARHTGVYSCKA 2330
Query: 713 VNREGEA 719
N G A
Sbjct: 2331 WNDSGNA 2337
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/184 (20%), Positives = 68/184 (36%), Gaps = 12/184 (6%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWER-DGEIIKPKKNKYDFEKRGH-IRK 1073
P+F+ Q K + ++ + T + W++ DG +I+ KY E +
Sbjct: 305 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQ-SGGKYKIENGPDGSGR 363
Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAE------VTVVELP--PEIITRLQNQKVNKGNKAT 1125
L I HD Y + R++ + + V + P PE + Q+ + G+
Sbjct: 364 LIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVK 423
Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
+ +WFKD I + G + L I + + + G Y C+ N
Sbjct: 424 LYCKAAGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRCDATNKHG 483
Query: 1186 TAIL 1189
T L
Sbjct: 484 TTTL 487
Score = 43.2 bits (97), Expect = 0.002
Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 18/223 (8%)
Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVA 566
P FV++L P +G V E QV +T W + + F + D +A
Sbjct: 1327 PAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVNGQPLMKAHRFVLSQDFGYIA 1386
Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL---IVEAPLSDHGSEMTVXXXXXXXXXX 623
L I +PED GT+T V +N AG A ST ++ +D ++
Sbjct: 1387 -LNILYCYPEDNGTYTLVVRNRAGEAQSTVDINCGHTGGNFTDSFHPNSLHRIAELETPI 1445
Query: 624 XXADIL---EGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDI--AWLFKGEEIVP 676
A+ L E PT +K A V E + LE ++ I + + WLF G +
Sbjct: 1446 QRAEPLPDKEKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKA 1505
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
V +D L I + G YT+V N G A
Sbjct: 1506 SSRYRVL--NDFGFVS--LDIDYIIAEDSGKYTLVVYNSAGRA 1544
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT--ITWCKNNKPV-KALPTKSDGDTH 787
E + PQ IEPL S+ + +S +V P I W K+ +P+ + K D
Sbjct: 1986 EHDAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFG 2045
Query: 788 SITILKPKKV-KDEGVYTLKAENSEGIAETSAVITV 822
I++ V +D GVY++KA N++G AE A +TV
Sbjct: 2046 YISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQLTV 2081
Score = 41.5 bits (93), Expect = 0.006
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 526 TVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
TV F +V G P P +TW + +I+ +++ D L+I +V DA + V
Sbjct: 321 TVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRLIIEKVDAHDADMYMLV 380
Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMT 612
A+N G S L V S E T
Sbjct: 381 ARNDGGSFQSRFSLNVLQAKSPEAPEFT 408
Score = 41.5 bits (93), Expect = 0.006
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 821 TVEEPTEENA-EPPLFINRFQ-EITVKEKGTIKLVARVT-RNPVP-SITWYRNNEIISPS 876
+VE P E N+ E P F +I V E + AR+ N V ++ WY N + +
Sbjct: 914 SVERPEEFNSLEAPKFARELAGKIEVMENERVHFEARILPANDVKMTVEWYHNGNPLPAA 973
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
FD + L + + DSG Y VA N G++ + + EKV +++
Sbjct: 974 HRFHPMFDFGYVALDLLYAYPQ-DSGTYTLVARNELGEARSNVELVVGTEKVLYLE 1028
Score = 41.5 bits (93), Expect = 0.006
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 1285 EFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E P + +E + G VTL LV+ P EW++N ++ + + +
Sbjct: 2384 EKPQWVQGFENYENVGEGQTVTLHGLVEPSGDPHLRLEWLLNGTPLRNANRFRQEYEFGN 2443
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
A LTI V D+G+Y R N G A VT
Sbjct: 2444 AILTIVHVLPHDSGVYTCRAWNTQGEASTSATVT 2477
Score = 41.5 bits (93), Expect = 0.006
Identities = 53/264 (20%), Positives = 93/264 (35%), Gaps = 25/264 (9%)
Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
E+++ Q+ Q KL + + +E AP F +L+ +G +FE QV
Sbjct: 3534 ESHFKQHSQAKLQLTANDI------YNESDKRAPEFRTQLQNIGVLEGEFCRFETQVAPI 3587
Query: 537 PRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
P ++ WF+ + F+ D A L + P+D G + CVA N G
Sbjct: 3588 NDPYLKVEWFKDKKPVLLGHRFRSTLDF-GFACLDLLYALPDDTGEYHCVATNRHGQTMI 3646
Query: 595 TTELIVEAPL-----SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP------KAQ 643
+ +L + S + V ++ + P + P +
Sbjct: 3647 SAKLACQGASHVITDSQMPQGLRVSNVKKDNKNIYWSEQGGAVQPKQKQAPQFTIPLRNL 3706
Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
V E EC + P P + W G + + + + ++ S +I++
Sbjct: 3707 QVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDA--- 3763
Query: 704 QEGTYTVVAVNREGEASLPIVLKI 727
G +A N EGE L I
Sbjct: 3764 --GEVVAIARNTEGETISTATLDI 3785
Score = 40.7 bits (91), Expect = 0.011
Identities = 44/207 (21%), Positives = 76/207 (36%), Gaps = 6/207 (2%)
Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
A ++ PP F P++ + ++V P P + W K + V IE
Sbjct: 297 AALVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSGGKYKIE 355
Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSM 744
+ L I V Y +VA N G L + + E P+ +S
Sbjct: 356 NGPD-GSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQST 414
Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITI-LKPKKVKDEGV 802
+ G+SV L + G + W K+N+P+ + + + D + T+ + +K+ G
Sbjct: 415 TLYDGDSVKLYCKAAGE-GVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGW 473
Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN 829
Y A N G + V + N
Sbjct: 474 YRCDATNKHGTTTLKGRVVVNSRQKFN 500
Score = 40.7 bits (91), Expect = 0.011
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
P + I R++ Q + K T + T + ++WFKDG + SN +LT D L I
Sbjct: 1995 PLDSIDRMEFQSAHFQTKVTPQ---TDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDI 2051
Query: 1166 YDCDLDDAGEYSCEVGNSK 1184
+D+G YS + N+K
Sbjct: 2052 AHTVPEDSGVYSVKASNAK 2070
Score = 40.3 bits (90), Expect = 0.015
Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 730 GEKEPPQVIEPLKSMI--VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKS 782
G +EPP + PL++ + V +GE + L QV + + I W ++ + + T
Sbjct: 1189 GPQEPPTFVVPLQADLGDVEEGEPIHLECQVNPINDNSLKIIWLRDGQSLPHGHRFRTFY 1248
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
D S+ IL +D G YT +AENS G AET A I
Sbjct: 1249 DFGFVSLDILG-FYAQDAGTYTCRAENSLGQAETVATI 1285
Score = 40.3 bits (90), Expect = 0.015
Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%)
Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVV--GNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
PP+ + L S+ V +G+ AQ + +P+ ++ W N P+ A + + +
Sbjct: 2120 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 2179
Query: 791 ILKPKKV--KDEGVYTLKAENSEGIAETSAVIT----------------------VEEPT 826
L + +D G Y++ +NSEG TS ++ +E P
Sbjct: 2180 SLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQLSCTTRAAILGDTQHEQSWQRIQEIEAPR 2239
Query: 827 EENAEP-------PLFINRFQEITVKEKGTIKLV-ARV--TRNPVPSITWYRNNEIISPS 876
AEP P F+ Q + +G++ L+ AR+ +P + W+ N++ + S
Sbjct: 2240 APGAEPEGPVYEKPSFVQPLQSVGDLPEGSVALLEARLVPVNDPNLRVQWFYNDQPLMES 2299
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I+ + D + L I V + +G Y C A N +G + A V +
Sbjct: 2300 NWISTSNDFGCVSLRIAPVYAR-HTGVYSCKAWNDSGNAVTSANVGV 2345
Score = 39.5 bits (88), Expect = 0.026
Identities = 15/42 (35%), Positives = 23/42 (54%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
Q+P PL+N+ N+ C G P+PKVTW+ +G +
Sbjct: 3695 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQ 3736
Score = 39.1 bits (87), Expect = 0.034
Identities = 58/279 (20%), Positives = 103/279 (36%), Gaps = 22/279 (7%)
Query: 490 EKIDKLPVFEKPT-SEEQSMAPIF-----VEKLRPKHTPDGSTVQFECQVEGY--PRPQI 541
E ++ + E P +E ++ AP++ ++ K +G V FE + PR Q+
Sbjct: 2624 ESWKRIQILEAPKEAEPEAPAPVYDHPAITTQIDDKECNEGDHVHFEALITPVNDPRLQV 2683
Query: 542 TWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV- 600
W R + + + D + TL + +PED G + N G A S+ L
Sbjct: 2684 QWIRNGVPLAHGSKYAIQ-QDFGICTLDVAYTYPEDEGVYQLRIWNPEGEAVSSATLKCH 2742
Query: 601 --EAPLSD---HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK-PKAQYVDEGSDILLE 654
+A L D S + AD PP F ++ + E E
Sbjct: 2743 GKDAILGDVQHQESWKRIQEIEAPKQKLEEADPEPKGPPRFIQQLTSPGSLVENQPAHFE 2802
Query: 655 CRLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
+ + +P I W GE + + + +D ++ I + G + VA
Sbjct: 2803 ATVEPVDDPTLTINWFLNGEPMSASSRVKMI--NDFGWV--IMDIAQTEPRDSGEWKCVA 2858
Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
N GEA ++++ E ++P +RQ E+
Sbjct: 2859 KNAAGEAVSTATIEVQGKEVILQDSLQPQSLDRIRQIEA 2897
Score = 38.7 bits (86), Expect = 0.045
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 731 EKEPPQVIEPLKSMI--VRQGESVILSAQVVGNPRPTIT--WCKNNKPVKALPTKSDGDT 786
EKE P + +PL + I V + +++ L AQV T+ W N P+KA +
Sbjct: 1455 EKEVPTIAKPLPATIDSVHESQTLHLEAQVTPIDDNTLRYEWLFNGNPLKASSRYRVLND 1514
Query: 787 HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE 823
L + +D G YTL NS G AETS V+
Sbjct: 1515 FGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1553
Score = 38.7 bits (86), Expect = 0.045
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
PE T+LQN V +G FE ++ D V WFKD + + + T+D L
Sbjct: 3561 PEFRTQLQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACL 3620
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
+ DD GEY C N
Sbjct: 3621 DLLYALPDDTGEYHCVATN 3639
Score = 37.9 bits (84), Expect = 0.078
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
+P + W N I S I+ + L+I ++ + D+G+YKCVA+N G ++
Sbjct: 3348 DPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAA-DAGEYKCVATNVKGSATSV 3406
Query: 919 ARVTID----VEKVTFVKHLQKSYET-EEGKTVILECQTS 953
++ ++ ++ V+ L S E EG ++ LEC+ +
Sbjct: 3407 GKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVT 3446
Score = 37.5 bits (83), Expect = 0.10
Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNN 772
E EA P + PP+ L +++G+ L QV V +PR I W N
Sbjct: 3164 EIEAPRPAREDAPDADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNG 3223
Query: 773 KPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+PV K+ D + + L P + +D G +T +A N G E S + V
Sbjct: 3224 QPVNHTNRMKAIHDFGFVVLQLTPAEPQDSGTWTCRATNQHGSDEVSTELKV 3275
Score = 37.1 bits (82), Expect = 0.14
Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 1107 PEIITRLQNQ-KVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
P I+ LQ Q + +G A + + T V W KDG I SN ++ D
Sbjct: 2913 PAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKDGQPIFHSNRYKMVHDFGFAV 2972
Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIP 1221
L I DAGEY+ V N+ A S +F + IL P N VEI
Sbjct: 2973 LDILHLLKHDAGEYTFRVSNNSGEA-----STSTSFEVSESSGLILQPQNEQKAKAVEIL 3027
Query: 1222 DETL 1225
++ L
Sbjct: 3028 EDNL 3031
Score = 36.7 bits (81), Expect = 0.18
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 36/249 (14%)
Query: 709 TVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPT 765
T+ V++ + P+ L+ + K P+ L+S + +G+S L + V +P
Sbjct: 509 TLRKVDKVERSRTPVNQLQDVSASKSSPKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLR 568
Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
I W N K + A + T +D ++ I P V D+G YT+ A N G A SA I V
Sbjct: 569 IAWLLNGKGILASSRIVTFTDFGIAALEI-NPVNVFDQGEYTVVAVNPLGEARVSANIAV 627
Query: 823 --------------------------EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
+ P + + P F + + V E I L ++
Sbjct: 628 IGHGSFIQQQQSGSQFGGTAYQSKGAQAPAGTHLDLPNFHSDLRSQEVFEGQQIHLETKL 687
Query: 857 T--RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
T +P + W + + ++ Q L I S DSG Y C A N G+
Sbjct: 688 TPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSN-DSGLYSCRAFNKLGE 746
Query: 915 SSHGARVTI 923
S + A + I
Sbjct: 747 SENQATIII 755
Score = 36.3 bits (80), Expect = 0.24
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
P + L++Q+V +G + E +LT D V W DG+E+ ++ + T+ L
Sbjct: 664 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASL 723
Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
I +D+G YSC N
Sbjct: 724 DIPQTSSNDSGLYSCRAFN 742
Score = 36.3 bits (80), Expect = 0.24
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 733 EPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPV----KALPTKSDGD 785
+PP E L ++G+S+ L ++ V +P +TW +N +P+ + +P ++ D
Sbjct: 1723 QPPTFTENLADKEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPLPEASRFMPARNF-D 1781
Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
++ IL +D GVYT KA ++ G A TS +
Sbjct: 1782 YVNLDILALYG-EDSGVYTCKAVSAFGEAATSCTV 1815
Score = 36.3 bits (80), Expect = 0.24
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P + W+K+G L N + +TT + I S Y+++ASN G + V+
Sbjct: 2019 PNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEVQAQ 2078
Query: 1660 LKV 1662
L V
Sbjct: 2079 LTV 2081
Score = 36.3 bits (80), Expect = 0.24
Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
+P ++ A P F + + V E + VT P P +TW+ N NF
Sbjct: 3690 QPKQKQA--PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNF 3747
Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
DG + + + D+G+ +A N+ G++ A + I
Sbjct: 3748 DG--LHYLTVSKSRISDAGEVVAIARNTEGETISTATLDI 3785
Score = 35.9 bits (79), Expect = 0.32
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870
+ E E+P E+ + P FI I E + +VT P+ I W+++
Sbjct: 1971 VLEAPRAAAPEKPDAEH-DAPQFIEPLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDG 2029
Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ + S D I L I + E DSG Y ASN+ G + A++T+
Sbjct: 2030 QPLMNSNRFKLTTDFGYISLDIAHTVPE-DSGVYSVKASNAKGDAEVQAQLTV 2081
Score = 34.7 bits (76), Expect = 0.73
Identities = 17/66 (25%), Positives = 31/66 (46%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P V+W +GN+L ++ +Y T + + I + + S Y+ A N G S + T
Sbjct: 693 PDLRVVWLLDGNELPSNDKYRQTLSHGFASLDIPQTSSNDSGLYSCRAFNKLGESENQAT 752
Query: 1660 LKVYDK 1665
+ + K
Sbjct: 753 IIIVPK 758
Score = 34.3 bits (75), Expect = 0.97
Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
+P F L+ EV E LE + IN VVW DG + P +KY
Sbjct: 663 LPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFA 721
Query: 1073 KLYIRNTSVHDEGEYSC 1089
L I TS +D G YSC
Sbjct: 722 SLDIPQTSSNDSGLYSC 738
Score = 34.3 bits (75), Expect = 0.97
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 1013 KETIPEFIRKLQDFEVKEK-DVAILEVEI---NSETADVVWERDGEIIKPKKNKYDFEKR 1068
++ P+F+ ++Q F +++ + E I N T V W +DG+ + P N+ +
Sbjct: 785 QDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNANRIQIFQN 843
Query: 1069 GHIRKLYIRNTSVHDEGEYSCIL 1091
+ L + T D G Y+C+L
Sbjct: 844 FGVVSLSLHPTYPEDAGVYTCVL 866
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P +V W K+G + + Y + +V+ I L + + +YT SN +G +S +
Sbjct: 2943 PSIKVEWLKDGQPIFHSNRYKMVHDFGFAVLDILHLLKHDAGEYTFRVSNNSGEASTSTS 3002
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIE 1686
+V S+ G ++ + +++ +E
Sbjct: 3003 FEV----SESSGLILQPQNEQKAKAVE 3025
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASL 1345
PK + ++ G L + Y PN W++N K I D A+L
Sbjct: 536 PKFEGSLQSQQLVEGQSARLEIKYTPVEDPNLRIAWLLNGKGILASSRIVTFTDFGIAAL 595
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
I V D G Y + N G A V N+ ++
Sbjct: 596 EINPVNVFDQGEYTVVAVNPLGEARVSANIAVI 628
Score = 33.1 bits (72), Expect = 2.2
Identities = 47/216 (21%), Positives = 81/216 (37%), Gaps = 12/216 (5%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVAT 567
P F LR + +G + E ++ P ++ W + PS D A+
Sbjct: 664 PNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNEL-PSNDKYRQTLSHGFAS 722
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXA 626
L I + D+G ++C A N G + + +I+ P SD E A
Sbjct: 723 LDIPQTSSNDSGLYSCRAFNKLGESENQATIII-VPKSDLQQFEQHRQLDVEDVREIQFA 781
Query: 627 DILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVA 683
+ + P F + + + + E E R+ I +P ++WL G+ + P+ N
Sbjct: 782 HSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPL-PNAN---R 837
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I+ + L + G YT V N G+A
Sbjct: 838 IQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 873
Score = 33.1 bits (72), Expect = 2.2
Identities = 16/47 (34%), Positives = 25/47 (53%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
V W KDG + +N IQ+ + L ++ +DAG Y+C + NS
Sbjct: 823 VSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNS 869
Score = 33.1 bits (72), Expect = 2.2
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 1106 PPEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
PP+ +T+L + V +G + FE I + V+W+ +G+ + S+ L D
Sbjct: 2120 PPKFVTQLHSLDGVVEGQPSHFEAQFIPFSDPKTSVQWYLNGNPLSASSRRILRNDFGLV 2179
Query: 1162 KLKIYDCDLDDAGEYSCEVGNSK 1184
L + +DAGEYS V NS+
Sbjct: 2180 SLDLQYTLGEDAGEYSVVVKNSE 2202
Score = 32.7 bits (71), Expect = 3.0
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 7/116 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKN 771
R+ EA P + + E P ++ L+ + +G S L Q V +P + W K+
Sbjct: 2893 RQIEAGKPAPEERPDQQFEAPAIVNALQVQGALEEGGSAHLQTQFTPVADPSIKVEWLKD 2952
Query: 772 NKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
+P+ D + IL K D G YT + N+ G A TS V E
Sbjct: 2953 GQPIFHSNRYKMVHDFGFAVLDILHLLK-HDAGEYTFRVSNNSGEASTSTSFEVSE 3007
Score = 32.3 bits (70), Expect = 3.9
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 735 PQVIEPLKSMIVRQGES--VILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITI 791
P+ + L + + + E+ V L A V +P I W N +P+ K+ + I +
Sbjct: 1061 PKFLNDLPDIQLNEHENIHVDLRATPVNDPTMVIEWFVNGRPLLTGSRVKTLNEFGFIAL 1120
Query: 792 -LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
+K +D G Y+++A N G A VITV
Sbjct: 1121 DIKGAIAEDSGTYSVRASNLLGEAIRQCVITV 1152
Score = 32.3 bits (70), Expect = 3.9
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTIT--WCKN 771
+E EA P ++ +PP ++ L I +G++V L AQV ++T W N
Sbjct: 1307 QEIEAPKPAPQEVPDLPHQPPAFVKQLGPAIQCMEGDNVYLEAQVTPTDDNSLTYEWLVN 1366
Query: 772 NKPV-KA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
+P+ KA D ++ IL +D G YTL N G A+++ I
Sbjct: 1367 GQPLMKAHRFVLSQDFGYIALNILYCYP-EDNGTYTLVVRNRAGEAQSTVDI 1417
Score = 31.9 bits (69), Expect = 5.2
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIA 814
Q + +P ++W K+ +P+ + L P +D GVYT NS G A
Sbjct: 814 QPINDPTLRVSWLKDGQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQA 873
Query: 815 ETSAVIT 821
++SA +T
Sbjct: 874 QSSAELT 880
Score = 31.1 bits (67), Expect = 9.0
Identities = 16/66 (24%), Positives = 29/66 (43%)
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
Q P +W + + + K + D SL I D+G+Y ++ N G A+V
Sbjct: 2016 QTDPNLRIQWFKDGQPLMNSNRFKLTTDFGYISLDIAHTVPEDSGVYSVKASNAKGDAEV 2075
Query: 1372 EMNVTI 1377
+ +T+
Sbjct: 2076 QAQLTV 2081
Score = 31.1 bits (67), Expect = 9.0
Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ G P P+V W+ NGN+ + + + + + + + + S + + A NT G +
Sbjct: 3720 VTGYPRPKVTWFINGNQCLHGHRFKLNF-DGLHYLTVSKSRISDAGEVVAIARNTEGETI 3778
Query: 1656 VEVTLKVY 1663
TL ++
Sbjct: 3779 STATLDIF 3786
>U58729-3|AAM54204.1| 955|Caenorhabditis elegans Hypothetical protein
F02G3.1c protein.
Length = 955
Score = 80.6 bits (190), Expect = 1e-14
Identities = 152/724 (20%), Positives = 267/724 (36%), Gaps = 63/724 (8%)
Query: 1112 RLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYD 1167
RLQN++ +++ G DA + W++DG I +F + + + Q L I
Sbjct: 57 RLQNRRSGDNFLVVCKVKDFDGAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQ-LMINR 115
Query: 1168 CDLDDAGEYSCEVG----NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD- 1222
+ D G+Y+C+ + +A ++ +P F L + E T A + E+
Sbjct: 116 PKISDGGKYTCKTEIQGEQQEVSAEISFVDPP-KF-LNVQESQHPEEGTRAEIVCEVEGT 173
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT-EDDQCEYTCVLLDAKSTTKLKV 1281
+ L+V W +++T + + L I T + D Y C S L V
Sbjct: 174 DQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAAQYSSFETLSV 233
Query: 1282 EVVEFP-PKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
V + P I D R G + L P+P +W + + K ++
Sbjct: 234 NVTGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNV 293
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
+ L I+ + + DAG YK N G + ++ + KP K + + +
Sbjct: 294 EE--GLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYVVKEGDDVE 351
Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
+ G+ T +V + E +V+N + + +S R +
Sbjct: 352 LVCSY-HGEGHVTA-KFVSGHSEF------AVRN--------EAVSAGNSEEIRPESNES 395
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR- 1517
+++ SE +E ET Q K +N+ E + + + W R
Sbjct: 396 EEVTTTSENSE------ETSTQDEVELKSAENVNDEEDHTSQQDDGEQDEQEESKKWKRF 449
Query: 1518 --DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT- 1574
D + + EN+ Y C ND G V VGI P +
Sbjct: 450 ADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 509
Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIK 1633
+ I+ G+ V + +P P+ W+KNG ++E N I T+ ++ + ++
Sbjct: 510 YTGPHIRSFD--GNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLE 567
Query: 1634 ELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-------SRESVTI 1685
S + YT A N G ++ + P+ P G + + S ES
Sbjct: 568 NFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPSGMNCKKMVYPNYGKCSFESDIY 627
Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQ 1744
E K +EL +E+ E D N W V E I L N +Y+ + A
Sbjct: 628 E-KEESKPQTMELLVAKLEEMESDYN-WSHAQPVSVPFEDDLTIPNLTSNTQYVIKARAV 685
Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
N G SE SE I ++T P ++ ++W + + GSP++ +KV
Sbjct: 686 NEAGSSE--YSEEISLETT--DPWAPQAPGSVAMKCSDYCTVSW-DTPNDHGSPLLKFKV 740
Query: 1805 EIKQ 1808
I++
Sbjct: 741 TIQE 744
Score = 77.4 bits (182), Expect = 1e-13
Identities = 118/552 (21%), Positives = 221/552 (40%), Gaps = 48/552 (8%)
Query: 648 GSDILLECRLV----AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
G + L+ C++ A + I W ++ +++P ++ IE Y + L I K
Sbjct: 64 GDNFLVVCKVKDFDGAASDAKIEW-YRDGKLIPRFGSTMTIE---RTYSNQLMINRPKIS 119
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
G YT +GE + + +PP+ + +S +G + +V G +
Sbjct: 120 DGGKYTC-KTEIQGEQQ---EVSAEISFVDPPKFLNVQESQHPEEGTRAEIVCEVEGTDQ 175
Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKV---KDEGVYTLKAENSEGIAETSAVI 820
+ W N + + + + IL KD+G+Y A S +
Sbjct: 176 LEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAAQYSSFETLSVNV 235
Query: 821 T-VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
T PT + P N + I E TI+L P P+ W+ ++ + + +
Sbjct: 236 TGYARPTITVFDVP---NGNRGI---EGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSD 289
Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
N + E + L+I +++SE D+G YKCVA+N+ G + + + ++ +KH Y
Sbjct: 290 KHNVE-EGL-LIIESLNSE-DAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKH---EYV 343
Query: 940 TEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
+EG V L C V+ K+ E + E + G +V
Sbjct: 344 VKEGDDVELVCSYHGEGHVTAKFVSGHSEFA--VRNEAVSAGNSEEIRPESNESEEVTTT 401
Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
+ETST V+ E + +D ++ D E + + W+R + +
Sbjct: 402 S--ENSEETSTQDEVELKSAENVNDEEDHTSQQDD-----GEQDEQEESKKWKRFADDVN 454
Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA-EVTVVE-LPPEIITRLQN 1115
++ E+ I L I++ S+ D +Y+C + +++ T +VT V + P +
Sbjct: 455 NQRISVRAEENKLI--LTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHYTG 512
Query: 1116 QKVNK--GNKATFEIELTK-GDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCD-L 1170
+ GN + +++ WFK+G E++ + IQ+ G KL + + D
Sbjct: 513 PHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGS 572
Query: 1171 DDAGEYSCEVGN 1182
D+ G Y+C N
Sbjct: 573 DNFGVYTCRADN 584
Score = 74.5 bits (175), Expect = 7e-13
Identities = 124/630 (19%), Positives = 245/630 (38%), Gaps = 46/630 (7%)
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++I P T + ++ N D G Y C + A ++
Sbjct: 85 IEWYRDGKLI-PRFGSTMTIERTYSNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISF 143
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREI-IQEGR 980
V+ F+ ++Q+S EEG + C+ T + W N + R E
Sbjct: 144 -VDPPKFL-NVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENN 201
Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV------KETIPEFIRKLQDFEVKEKDVA 1034
D G+ C + L V + TI F + ++ +
Sbjct: 202 QILYIPHFTAKKDDGIYNCNAAQYSSFETLSVNVTGYARPTITVFDVPNGNRGIEGHTIE 261
Query: 1035 ILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
+ + W D E+ + +K++ E+ L I + + D G Y C+ +
Sbjct: 262 LKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEEG----LLIIESLNSEDAGTYKCVANN 317
Query: 1094 ESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS 1149
+ E T V L P++ + V +G+ +G ++ SE
Sbjct: 318 TVGSNERTFDLAVFLKPKVDLK-HEYVVKEGDDVELVCSYHGEGHVTAKFVSGHSEFAVR 376
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
N + G ++++ + +++ E + NS+ T+ T +E L+ E +
Sbjct: 377 N--EAVSAGNSEEIRP---ESNESEEVTTTSENSEETS--TQDEVE----LKSAENVNDE 425
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
+ + DE + +K+ + + ++ ++ ++ K L I+ + +D +YTC
Sbjct: 426 EDHTSQQDDGEQDEQEESKKWKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCA 485
Query: 1270 LL-DAKSTTKLKVEVVEFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
+ DA + K+ + PP + Y + R G+ V++ D A P P W N K
Sbjct: 486 VSNDAGTVNKVTQVGIIHPPTLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKE 545
Query: 1328 IK-KCKHTKPSIDSKSASLTIKKVENTD-AGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
++ + S LT++ + +D G+Y R +N G + +++V + P+ P
Sbjct: 546 VEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPS 605
Query: 1386 KPNILEIDSSSINIC-----WDEPENTGNSTIIYYVVEYQEIDTT-EWISVKNIT---KT 1436
N ++ + C E E + T+ V + +E+++ W + ++ +
Sbjct: 606 GMNCKKMVYPNYGKCSFESDIYEKEESKPQTMELLVAKLEEMESDYNWSHAQPVSVPFED 665
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
+I NL +N+ Y +A AVNE S+ SE
Sbjct: 666 DLTIPNLTSNTQYVIKARAVNEAGSSEYSE 695
Score = 50.4 bits (115), Expect = 1e-05
Identities = 47/229 (20%), Positives = 84/229 (36%), Gaps = 7/229 (3%)
Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654
+ +L++ P G + T A+I PP F ++Q+ +EG+ +
Sbjct: 108 SNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIV 167
Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
C + + ++ W F G + DE E + + KK +G Y A
Sbjct: 168 CEVEGTDQLEVFWQFNG--VTLDETSQRGYEFSENNQILYIPHFTAKK-DDGIYNCNAAQ 224
Query: 715 REGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
+L + + TG P V + +G ++ L VG P+PT W +
Sbjct: 225 YSSFETLSVNV---TGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDD 281
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
V + + I++ +D G Y A N+ G E + + V
Sbjct: 282 EVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAV 330
Score = 46.0 bits (104), Expect = 3e-04
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G T++ +C G P+P WF + + ++ + ++ L+I + EDAGT+
Sbjct: 256 EGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEE---GLLIIESLNSEDAGTYK 312
Query: 583 CVAKNAAGFASSTTELIV 600
CVA N G T +L V
Sbjct: 313 CVANNTVGSNERTFDLAV 330
Score = 40.7 bits (91), Expect = 0.011
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
I N+ + + + A N G S S+ + LE T P P AP + M S+ S
Sbjct: 669 IPNLTSNTQYVIKARAVNEAGSS--EYSEEISLE--TTDPWAPQAPGSVAMKCSDYCTVS 724
Query: 1987 WGTPEWDGGAPLLGYNIAIRDV 2008
W TP D G+PLL + + I+++
Sbjct: 725 WDTPN-DHGSPLLKFKVTIQEM 745
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 9/128 (7%)
Query: 789 ITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
I +K ++D YT N G + + + V + PT + P I F +
Sbjct: 468 ILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHYTGP-HIRSF------DG 520
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKC 906
T+ + V+ P P W++N + + + Q F G + +L + N D + G Y C
Sbjct: 521 NTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTC 580
Query: 907 VASNSAGK 914
A N G+
Sbjct: 581 RADNGVGQ 588
Score = 35.1 bits (77), Expect = 0.55
Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED-AGTF 581
DG+TV C V P P+ WF+ ++ + + + L + D G +
Sbjct: 519 DGNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVY 578
Query: 582 TCVAKNAAGFASSTTELI-VEAPLSDHG 608
TC A N G ++I V +P + G
Sbjct: 579 TCRADNGVGQLEKQIDVIKVVSPATPSG 606
Score = 32.7 bits (71), Expect = 3.0
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDH 607
++N L I+ + EDA +TC N AG + T++ I+ P H
Sbjct: 463 EENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 509
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/87 (20%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ +H +G+ + C+VEG + ++ W + + + ++N +
Sbjct: 147 PKFLNVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYI 206
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTT 596
+D G + C NAA ++S T
Sbjct: 207 PHFTAKKDDGIYNC---NAAQYSSFET 230
>U58729-2|AAM54203.1| 913|Caenorhabditis elegans Hypothetical protein
F02G3.1b protein.
Length = 913
Score = 80.6 bits (190), Expect = 1e-14
Identities = 152/724 (20%), Positives = 267/724 (36%), Gaps = 63/724 (8%)
Query: 1112 RLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYD 1167
RLQN++ +++ G DA + W++DG I +F + + + Q L I
Sbjct: 30 RLQNRRSGDNFLVVCKVKDFDGAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQ-LMINR 88
Query: 1168 CDLDDAGEYSCEVG----NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD- 1222
+ D G+Y+C+ + +A ++ +P F L + E T A + E+
Sbjct: 89 PKISDGGKYTCKTEIQGEQQEVSAEISFVDPP-KF-LNVQESQHPEEGTRAEIVCEVEGT 146
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT-EDDQCEYTCVLLDAKSTTKLKV 1281
+ L+V W +++T + + L I T + D Y C S L V
Sbjct: 147 DQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAAQYSSFETLSV 206
Query: 1282 EVVEFP-PKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
V + P I D R G + L P+P +W + + K ++
Sbjct: 207 NVTGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNV 266
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
+ L I+ + + DAG YK N G + ++ + KP K + + +
Sbjct: 267 EE--GLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYVVKEGDDVE 324
Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
+ G+ T +V + E +V+N + + +S R +
Sbjct: 325 LVCSY-HGEGHVTA-KFVSGHSEF------AVRN--------EAVSAGNSEEIRPESNES 368
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR- 1517
+++ SE +E ET Q K +N+ E + + + W R
Sbjct: 369 EEVTTTSENSE------ETSTQDEVELKSAENVNDEEDHTSQQDDGEQDEQEESKKWKRF 422
Query: 1518 --DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT- 1574
D + + EN+ Y C ND G V VGI P +
Sbjct: 423 ADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 482
Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIK 1633
+ I+ G+ V + +P P+ W+KNG ++E N I T+ ++ + ++
Sbjct: 483 YTGPHIRSFD--GNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLE 540
Query: 1634 ELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-------SRESVTI 1685
S + YT A N G ++ + P+ P G + + S ES
Sbjct: 541 NFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPSGMNCKKMVYPNYGKCSFESDIY 600
Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQ 1744
E K +EL +E+ E D N W V E I L N +Y+ + A
Sbjct: 601 E-KEESKPQTMELLVAKLEEMESDYN-WSHAQPVSVPFEDDLTIPNLTSNTQYVIKARAV 658
Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
N G SE SE I ++T P ++ ++W + + GSP++ +KV
Sbjct: 659 NEAGSSE--YSEEISLETT--DPWAPQAPGSVAMKCSDYCTVSW-DTPNDHGSPLLKFKV 713
Query: 1805 EIKQ 1808
I++
Sbjct: 714 TIQE 717
Score = 78.2 bits (184), Expect = 6e-14
Identities = 125/579 (21%), Positives = 231/579 (39%), Gaps = 55/579 (9%)
Query: 628 ILEGIPP----TFSKKPKAQYVDE---GSDILLECRLV----AIPEPDIAWLFKGEEIVP 676
+L GIP T S P + + G + L+ C++ A + I W ++ +++P
Sbjct: 10 LLAGIPAISGWTLSLSPTEERLQNRRSGDNFLVVCKVKDFDGAASDAKIEW-YRDGKLIP 68
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
++ IE Y + L I K G YT +GE + + +PP+
Sbjct: 69 RFGSTMTIE---RTYSNQLMINRPKISDGGKYTC-KTEIQGEQQ---EVSAEISFVDPPK 121
Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796
+ +S +G + +V G + + W N + + + + IL
Sbjct: 122 FLNVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPH 181
Query: 797 V---KDEGVYTLKAENSEGIAETSAVIT-VEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
KD+G+Y A S +T PT + P N + I E TI+L
Sbjct: 182 FTAKKDDGIYNCNAAQYSSFETLSVNVTGYARPTITVFDVP---NGNRGI---EGHTIEL 235
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
P P+ W+ ++ + + + N + E + L+I +++SE D+G YKCVA+N+
Sbjct: 236 KCGAVGKPKPTYKWFFEDDEVPIARSDKHNVE-EGL-LIIESLNSE-DAGTYKCVANNTV 292
Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGM 970
G + + + ++ +KH Y +EG V L C V+ K+ E +
Sbjct: 293 GSNERTFDLAVFLKPKVDLKH---EYVVKEGDDVELVCSYHGEGHVTAKFVSGHSEFA-- 347
Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030
E + G +V +ETST V+ E + +D ++
Sbjct: 348 VRNEAVSAGNSEEIRPESNESEEVTTTS--ENSEETSTQDEVELKSAENVNDEEDHTSQQ 405
Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
D E + + W+R + + ++ E+ I L I++ S+ D +Y+C
Sbjct: 406 DD-----GEQDEQEESKKWKRFADDVNNQRISVRAEENKLI--LTIKSISLEDAADYTCA 458
Query: 1091 LRDESCTA-EVTVVE-LPPEIITRLQNQKVNK--GNKATFEIELTK-GDALVRWFKDGSE 1145
+ +++ T +VT V + P + + GN + +++ WFK+G E
Sbjct: 459 VSNDAGTVNKVTQVGIIHPPTLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKE 518
Query: 1146 IQFSN-HIQLTIDGKKQKLKIYDCD-LDDAGEYSCEVGN 1182
++ + IQ+ G KL + + D D+ G Y+C N
Sbjct: 519 VEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADN 557
Score = 74.5 bits (175), Expect = 7e-13
Identities = 124/630 (19%), Positives = 245/630 (38%), Gaps = 46/630 (7%)
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++I P T + ++ N D G Y C + A ++
Sbjct: 58 IEWYRDGKLI-PRFGSTMTIERTYSNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISF 116
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREI-IQEGR 980
V+ F+ ++Q+S EEG + C+ T + W N + R E
Sbjct: 117 -VDPPKFL-NVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENN 174
Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV------KETIPEFIRKLQDFEVKEKDVA 1034
D G+ C + L V + TI F + ++ +
Sbjct: 175 QILYIPHFTAKKDDGIYNCNAAQYSSFETLSVNVTGYARPTITVFDVPNGNRGIEGHTIE 234
Query: 1035 ILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
+ + W D E+ + +K++ E+ L I + + D G Y C+ +
Sbjct: 235 LKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEEG----LLIIESLNSEDAGTYKCVANN 290
Query: 1094 ESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS 1149
+ E T V L P++ + V +G+ +G ++ SE
Sbjct: 291 TVGSNERTFDLAVFLKPKVDLK-HEYVVKEGDDVELVCSYHGEGHVTAKFVSGHSEFAVR 349
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
N + G ++++ + +++ E + NS+ T+ T +E L+ E +
Sbjct: 350 N--EAVSAGNSEEIRP---ESNESEEVTTTSENSEETS--TQDEVE----LKSAENVNDE 398
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
+ + DE + +K+ + + ++ ++ ++ K L I+ + +D +YTC
Sbjct: 399 EDHTSQQDDGEQDEQEESKKWKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCA 458
Query: 1270 LL-DAKSTTKLKVEVVEFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
+ DA + K+ + PP + Y + R G+ V++ D A P P W N K
Sbjct: 459 VSNDAGTVNKVTQVGIIHPPTLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKE 518
Query: 1328 IK-KCKHTKPSIDSKSASLTIKKVENTD-AGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
++ + S LT++ + +D G+Y R +N G + +++V + P+ P
Sbjct: 519 VEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPS 578
Query: 1386 KPNILEIDSSSINIC-----WDEPENTGNSTIIYYVVEYQEIDTT-EWISVKNIT---KT 1436
N ++ + C E E + T+ V + +E+++ W + ++ +
Sbjct: 579 GMNCKKMVYPNYGKCSFESDIYEKEESKPQTMELLVAKLEEMESDYNWSHAQPVSVPFED 638
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
+I NL +N+ Y +A AVNE S+ SE
Sbjct: 639 DLTIPNLTSNTQYVIKARAVNEAGSSEYSE 668
Score = 50.4 bits (115), Expect = 1e-05
Identities = 47/229 (20%), Positives = 84/229 (36%), Gaps = 7/229 (3%)
Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654
+ +L++ P G + T A+I PP F ++Q+ +EG+ +
Sbjct: 81 SNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIV 140
Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
C + + ++ W F G + DE E + + KK +G Y A
Sbjct: 141 CEVEGTDQLEVFWQFNG--VTLDETSQRGYEFSENNQILYIPHFTAKK-DDGIYNCNAAQ 197
Query: 715 REGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
+L + + TG P V + +G ++ L VG P+PT W +
Sbjct: 198 YSSFETLSVNV---TGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDD 254
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
V + + I++ +D G Y A N+ G E + + V
Sbjct: 255 EVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAV 303
Score = 46.0 bits (104), Expect = 3e-04
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G T++ +C G P+P WF + + ++ + ++ L+I + EDAGT+
Sbjct: 229 EGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEE---GLLIIESLNSEDAGTYK 285
Query: 583 CVAKNAAGFASSTTELIV 600
CVA N G T +L V
Sbjct: 286 CVANNTVGSNERTFDLAV 303
Score = 40.7 bits (91), Expect = 0.011
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
I N+ + + + A N G S S+ + LE T P P AP + M S+ S
Sbjct: 642 IPNLTSNTQYVIKARAVNEAGSS--EYSEEISLE--TTDPWAPQAPGSVAMKCSDYCTVS 697
Query: 1987 WGTPEWDGGAPLLGYNIAIRDV 2008
W TP D G+PLL + + I+++
Sbjct: 698 WDTPN-DHGSPLLKFKVTIQEM 718
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 9/128 (7%)
Query: 789 ITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
I +K ++D YT N G + + + V + PT + P I F +
Sbjct: 441 ILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHYTGP-HIRSF------DG 493
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKC 906
T+ + V+ P P W++N + + + Q F G + +L + N D + G Y C
Sbjct: 494 NTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTC 553
Query: 907 VASNSAGK 914
A N G+
Sbjct: 554 RADNGVGQ 561
Score = 35.1 bits (77), Expect = 0.55
Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED-AGTF 581
DG+TV C V P P+ WF+ ++ + + + L + D G +
Sbjct: 492 DGNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVY 551
Query: 582 TCVAKNAAGFASSTTELI-VEAPLSDHG 608
TC A N G ++I V +P + G
Sbjct: 552 TCRADNGVGQLEKQIDVIKVVSPATPSG 579
Score = 32.7 bits (71), Expect = 3.0
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDH 607
++N L I+ + EDA +TC N AG + T++ I+ P H
Sbjct: 436 EENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 482
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/87 (20%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ +H +G+ + C+VEG + ++ W + + + ++N +
Sbjct: 120 PKFLNVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYI 179
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTT 596
+D G + C NAA ++S T
Sbjct: 180 PHFTAKKDDGIYNC---NAAQYSSFET 203
>U58729-1|AAM54202.1| 928|Caenorhabditis elegans Hypothetical protein
F02G3.1a protein.
Length = 928
Score = 80.6 bits (190), Expect = 1e-14
Identities = 152/724 (20%), Positives = 267/724 (36%), Gaps = 63/724 (8%)
Query: 1112 RLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYD 1167
RLQN++ +++ G DA + W++DG I +F + + + Q L I
Sbjct: 30 RLQNRRSGDNFLVVCKVKDFDGAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQ-LMINR 88
Query: 1168 CDLDDAGEYSCEVG----NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD- 1222
+ D G+Y+C+ + +A ++ +P F L + E T A + E+
Sbjct: 89 PKISDGGKYTCKTEIQGEQQEVSAEISFVDPP-KF-LNVQESQHPEEGTRAEIVCEVEGT 146
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT-EDDQCEYTCVLLDAKSTTKLKV 1281
+ L+V W +++T + + L I T + D Y C S L V
Sbjct: 147 DQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAAQYSSFETLSV 206
Query: 1282 EVVEFP-PKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
V + P I D R G + L P+P +W + + K ++
Sbjct: 207 NVTGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNV 266
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
+ L I+ + + DAG YK N G + ++ + KP K + + +
Sbjct: 267 EE--GLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYVVKEGDDVE 324
Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
+ G+ T +V + E +V+N + + +S R +
Sbjct: 325 LVCSY-HGEGHVTA-KFVSGHSEF------AVRN--------EAVSAGNSEEIRPESNES 368
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR- 1517
+++ SE +E ET Q K +N+ E + + + W R
Sbjct: 369 EEVTTTSENSE------ETSTQDEVELKSAENVNDEEDHTSQQDDGEQDEQEESKKWKRF 422
Query: 1518 --DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT- 1574
D + + EN+ Y C ND G V VGI P +
Sbjct: 423 ADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 482
Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIK 1633
+ I+ G+ V + +P P+ W+KNG ++E N I T+ ++ + ++
Sbjct: 483 YTGPHIRSFD--GNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLE 540
Query: 1634 ELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-------SRESVTI 1685
S + YT A N G ++ + P+ P G + + S ES
Sbjct: 541 NFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPSGMNCKKMVYPNYGKCSFESDIY 600
Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQ 1744
E K +EL +E+ E D N W V E I L N +Y+ + A
Sbjct: 601 E-KEESKPQTMELLVAKLEEMESDYN-WSHAQPVSVPFEDDLTIPNLTSNTQYVIKARAV 658
Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
N G SE SE I ++T P ++ ++W + + GSP++ +KV
Sbjct: 659 NEAGSSE--YSEEISLETT--DPWAPQAPGSVAMKCSDYCTVSW-DTPNDHGSPLLKFKV 713
Query: 1805 EIKQ 1808
I++
Sbjct: 714 TIQE 717
Score = 78.2 bits (184), Expect = 6e-14
Identities = 125/579 (21%), Positives = 231/579 (39%), Gaps = 55/579 (9%)
Query: 628 ILEGIPP----TFSKKPKAQYVDE---GSDILLECRLV----AIPEPDIAWLFKGEEIVP 676
+L GIP T S P + + G + L+ C++ A + I W ++ +++P
Sbjct: 10 LLAGIPAISGWTLSLSPTEERLQNRRSGDNFLVVCKVKDFDGAASDAKIEW-YRDGKLIP 68
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
++ IE Y + L I K G YT +GE + + +PP+
Sbjct: 69 RFGSTMTIE---RTYSNQLMINRPKISDGGKYTC-KTEIQGEQQ---EVSAEISFVDPPK 121
Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796
+ +S +G + +V G + + W N + + + + IL
Sbjct: 122 FLNVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPH 181
Query: 797 V---KDEGVYTLKAENSEGIAETSAVIT-VEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
KD+G+Y A S +T PT + P N + I E TI+L
Sbjct: 182 FTAKKDDGIYNCNAAQYSSFETLSVNVTGYARPTITVFDVP---NGNRGI---EGHTIEL 235
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
P P+ W+ ++ + + + N + E + L+I +++SE D+G YKCVA+N+
Sbjct: 236 KCGAVGKPKPTYKWFFEDDEVPIARSDKHNVE-EGL-LIIESLNSE-DAGTYKCVANNTV 292
Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGM 970
G + + + ++ +KH Y +EG V L C V+ K+ E +
Sbjct: 293 GSNERTFDLAVFLKPKVDLKH---EYVVKEGDDVELVCSYHGEGHVTAKFVSGHSEFA-- 347
Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030
E + G +V +ETST V+ E + +D ++
Sbjct: 348 VRNEAVSAGNSEEIRPESNESEEVTTTS--ENSEETSTQDEVELKSAENVNDEEDHTSQQ 405
Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
D E + + W+R + + ++ E+ I L I++ S+ D +Y+C
Sbjct: 406 DD-----GEQDEQEESKKWKRFADDVNNQRISVRAEENKLI--LTIKSISLEDAADYTCA 458
Query: 1091 LRDESCTA-EVTVVE-LPPEIITRLQNQKVNK--GNKATFEIELTK-GDALVRWFKDGSE 1145
+ +++ T +VT V + P + + GN + +++ WFK+G E
Sbjct: 459 VSNDAGTVNKVTQVGIIHPPTLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKE 518
Query: 1146 IQFSN-HIQLTIDGKKQKLKIYDCD-LDDAGEYSCEVGN 1182
++ + IQ+ G KL + + D D+ G Y+C N
Sbjct: 519 VEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADN 557
Score = 74.5 bits (175), Expect = 7e-13
Identities = 124/630 (19%), Positives = 245/630 (38%), Gaps = 46/630 (7%)
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++I P T + ++ N D G Y C + A ++
Sbjct: 58 IEWYRDGKLI-PRFGSTMTIERTYSNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISF 116
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREI-IQEGR 980
V+ F+ ++Q+S EEG + C+ T + W N + R E
Sbjct: 117 -VDPPKFL-NVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENN 174
Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV------KETIPEFIRKLQDFEVKEKDVA 1034
D G+ C + L V + TI F + ++ +
Sbjct: 175 QILYIPHFTAKKDDGIYNCNAAQYSSFETLSVNVTGYARPTITVFDVPNGNRGIEGHTIE 234
Query: 1035 ILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
+ + W D E+ + +K++ E+ L I + + D G Y C+ +
Sbjct: 235 LKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEEG----LLIIESLNSEDAGTYKCVANN 290
Query: 1094 ESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS 1149
+ E T V L P++ + V +G+ +G ++ SE
Sbjct: 291 TVGSNERTFDLAVFLKPKVDLK-HEYVVKEGDDVELVCSYHGEGHVTAKFVSGHSEFAVR 349
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
N + G ++++ + +++ E + NS+ T+ T +E L+ E +
Sbjct: 350 N--EAVSAGNSEEIRP---ESNESEEVTTTSENSEETS--TQDEVE----LKSAENVNDE 398
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
+ + DE + +K+ + + ++ ++ ++ K L I+ + +D +YTC
Sbjct: 399 EDHTSQQDDGEQDEQEESKKWKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCA 458
Query: 1270 LL-DAKSTTKLKVEVVEFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
+ DA + K+ + PP + Y + R G+ V++ D A P P W N K
Sbjct: 459 VSNDAGTVNKVTQVGIIHPPTLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKE 518
Query: 1328 IK-KCKHTKPSIDSKSASLTIKKVENTD-AGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
++ + S LT++ + +D G+Y R +N G + +++V + P+ P
Sbjct: 519 VEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPS 578
Query: 1386 KPNILEIDSSSINIC-----WDEPENTGNSTIIYYVVEYQEIDTT-EWISVKNIT---KT 1436
N ++ + C E E + T+ V + +E+++ W + ++ +
Sbjct: 579 GMNCKKMVYPNYGKCSFESDIYEKEESKPQTMELLVAKLEEMESDYNWSHAQPVSVPFED 638
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
+I NL +N+ Y +A AVNE S+ SE
Sbjct: 639 DLTIPNLTSNTQYVIKARAVNEAGSSEYSE 668
Score = 50.4 bits (115), Expect = 1e-05
Identities = 47/229 (20%), Positives = 84/229 (36%), Gaps = 7/229 (3%)
Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654
+ +L++ P G + T A+I PP F ++Q+ +EG+ +
Sbjct: 81 SNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIV 140
Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
C + + ++ W F G + DE E + + KK +G Y A
Sbjct: 141 CEVEGTDQLEVFWQFNG--VTLDETSQRGYEFSENNQILYIPHFTAKK-DDGIYNCNAAQ 197
Query: 715 REGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
+L + + TG P V + +G ++ L VG P+PT W +
Sbjct: 198 YSSFETLSVNV---TGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDD 254
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
V + + I++ +D G Y A N+ G E + + V
Sbjct: 255 EVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAV 303
Score = 46.0 bits (104), Expect = 3e-04
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G T++ +C G P+P WF + + ++ + ++ L+I + EDAGT+
Sbjct: 229 EGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEE---GLLIIESLNSEDAGTYK 285
Query: 583 CVAKNAAGFASSTTELIV 600
CVA N G T +L V
Sbjct: 286 CVANNTVGSNERTFDLAV 303
Score = 40.7 bits (91), Expect = 0.011
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
I N+ + + + A N G S S+ + LE T P P AP + M S+ S
Sbjct: 642 IPNLTSNTQYVIKARAVNEAGSS--EYSEEISLE--TTDPWAPQAPGSVAMKCSDYCTVS 697
Query: 1987 WGTPEWDGGAPLLGYNIAIRDV 2008
W TP D G+PLL + + I+++
Sbjct: 698 WDTPN-DHGSPLLKFKVTIQEM 718
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 9/128 (7%)
Query: 789 ITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
I +K ++D YT N G + + + V + PT + P I F +
Sbjct: 441 ILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHYTGP-HIRSF------DG 493
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKC 906
T+ + V+ P P W++N + + + Q F G + +L + N D + G Y C
Sbjct: 494 NTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTC 553
Query: 907 VASNSAGK 914
A N G+
Sbjct: 554 RADNGVGQ 561
Score = 35.1 bits (77), Expect = 0.55
Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED-AGTF 581
DG+TV C V P P+ WF+ ++ + + + L + D G +
Sbjct: 492 DGNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVY 551
Query: 582 TCVAKNAAGFASSTTELI-VEAPLSDHG 608
TC A N G ++I V +P + G
Sbjct: 552 TCRADNGVGQLEKQIDVIKVVSPATPSG 579
Score = 32.7 bits (71), Expect = 3.0
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDH 607
++N L I+ + EDA +TC N AG + T++ I+ P H
Sbjct: 436 EENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 482
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/87 (20%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ +H +G+ + C+VEG + ++ W + + + ++N +
Sbjct: 120 PKFLNVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYI 179
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTT 596
+D G + C NAA ++S T
Sbjct: 180 PHFTAKKDDGIYNC---NAAQYSSFET 203
>AF456360-1|AAL60231.1| 928|Caenorhabditis elegans immunoglobulin
domain-containingprotein F02G3.1 protein.
Length = 928
Score = 80.6 bits (190), Expect = 1e-14
Identities = 152/724 (20%), Positives = 267/724 (36%), Gaps = 63/724 (8%)
Query: 1112 RLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYD 1167
RLQN++ +++ G DA + W++DG I +F + + + Q L I
Sbjct: 30 RLQNRRSGDNFLVVCKVKDFDGAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQ-LMINR 88
Query: 1168 CDLDDAGEYSCEVG----NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD- 1222
+ D G+Y+C+ + +A ++ +P F L + E T A + E+
Sbjct: 89 PKISDGGKYTCKTEIQGEQQEVSAEISFVDPP-KF-LNVQESQHPEEGTRAEIVCEVEGT 146
Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT-EDDQCEYTCVLLDAKSTTKLKV 1281
+ L+V W +++T + + L I T + D Y C S L V
Sbjct: 147 DQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAAQYSSFETLSV 206
Query: 1282 EVVEFP-PKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
V + P I D R G + L P+P +W + + K ++
Sbjct: 207 NVTGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNV 266
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
+ L I+ + + DAG YK N G + ++ + KP K + + +
Sbjct: 267 EE--GLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYVVKEGDDVE 324
Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
+ G+ T +V + E +V+N + + +S R +
Sbjct: 325 LVCSY-HGEGHVTA-KFVSGHSEF------AVRN--------EAVSAGNSEEIRPESNES 368
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR- 1517
+++ SE +E ET Q K +N+ E + + + W R
Sbjct: 369 EEVTTTSENSE------ETSTQDEVELKSAENVNDEEDHTSQQDDGEQDEQEESKKWKRF 422
Query: 1518 --DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT- 1574
D + + EN+ Y C ND G V VGI P +
Sbjct: 423 ADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 482
Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIK 1633
+ I+ G+ V + +P P+ W+KNG ++E N I T+ ++ + ++
Sbjct: 483 YTGPHIRSFD--GNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLE 540
Query: 1634 ELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-------SRESVTI 1685
S + YT A N G ++ + P+ P G + + S ES
Sbjct: 541 NFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPSGMNCKKMVYPNYGKCSFESDIY 600
Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQ 1744
E K +EL +E+ E D N W V E I L N +Y+ + A
Sbjct: 601 E-KEESKPQTMELLVAKLEEMESDYN-WSHAQPVSVPFEDDLTIPNLTSNTQYVIKARAV 658
Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
N G SE SE I ++T P ++ ++W + + GSP++ +KV
Sbjct: 659 NEAGSSE--YSEEISLETT--DPWAPQAPGSVAMKCSDYCTVSW-DTPNDHGSPLLKFKV 713
Query: 1805 EIKQ 1808
I++
Sbjct: 714 TIQE 717
Score = 78.2 bits (184), Expect = 6e-14
Identities = 125/579 (21%), Positives = 231/579 (39%), Gaps = 55/579 (9%)
Query: 628 ILEGIPP----TFSKKPKAQYVDE---GSDILLECRLV----AIPEPDIAWLFKGEEIVP 676
+L GIP T S P + + G + L+ C++ A + I W ++ +++P
Sbjct: 10 LLAGIPAISGWTLSLSPTEERLQNRRSGDNFLVVCKVKDFDGAASDAKIEW-YRDGKLIP 68
Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
++ IE Y + L I K G YT +GE + + +PP+
Sbjct: 69 RFGSTMTIE---RTYSNQLMINRPKISDGGKYTC-KTEIQGEQQ---EVSAEISFVDPPK 121
Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796
+ +S +G + +V G + + W N + + + + IL
Sbjct: 122 FLNVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPH 181
Query: 797 V---KDEGVYTLKAENSEGIAETSAVIT-VEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
KD+G+Y A S +T PT + P N + I E TI+L
Sbjct: 182 FTAKKDDGIYNCNAAQYSSFETLSVNVTGYARPTITVFDVP---NGNRGI---EGHTIEL 235
Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
P P+ W+ ++ + + + N + E + L+I +++SE D+G YKCVA+N+
Sbjct: 236 KCGAVGKPKPTYKWFFEDDEVPIARSDKHNVE-EGL-LIIESLNSE-DAGTYKCVANNTV 292
Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGM 970
G + + + ++ +KH Y +EG V L C V+ K+ E +
Sbjct: 293 GSNERTFDLAVFLKPKVDLKH---EYVVKEGDDVELVCSYHGEGHVTAKFVSGHSEFA-- 347
Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030
E + G +V +ETST V+ E + +D ++
Sbjct: 348 VRNEAVSAGNSEEIRPESNESEEVTTTS--ENSEETSTQDEVELKSAENVNDEEDHTSQQ 405
Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
D E + + W+R + + ++ E+ I L I++ S+ D +Y+C
Sbjct: 406 DD-----GEQDEQEESKKWKRFADDVNNQRISVRAEENKLI--LTIKSISLEDAADYTCA 458
Query: 1091 LRDESCTA-EVTVVE-LPPEIITRLQNQKVNK--GNKATFEIELTK-GDALVRWFKDGSE 1145
+ +++ T +VT V + P + + GN + +++ WFK+G E
Sbjct: 459 VSNDAGTVNKVTQVGIIHPPTLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKE 518
Query: 1146 IQFSN-HIQLTIDGKKQKLKIYDCD-LDDAGEYSCEVGN 1182
++ + IQ+ G KL + + D D+ G Y+C N
Sbjct: 519 VEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADN 557
Score = 74.5 bits (175), Expect = 7e-13
Identities = 124/630 (19%), Positives = 245/630 (38%), Gaps = 46/630 (7%)
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I WYR+ ++I P T + ++ N D G Y C + A ++
Sbjct: 58 IEWYRDGKLI-PRFGSTMTIERTYSNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISF 116
Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREI-IQEGR 980
V+ F+ ++Q+S EEG + C+ T + W N + R E
Sbjct: 117 -VDPPKFL-NVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENN 174
Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV------KETIPEFIRKLQDFEVKEKDVA 1034
D G+ C + L V + TI F + ++ +
Sbjct: 175 QILYIPHFTAKKDDGIYNCNAAQYSSFETLSVNVTGYARPTITVFDVPNGNRGIEGHTIE 234
Query: 1035 ILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
+ + W D E+ + +K++ E+ L I + + D G Y C+ +
Sbjct: 235 LKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEEG----LLIIESLNSEDAGTYKCVANN 290
Query: 1094 ESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS 1149
+ E T V L P++ + V +G+ +G ++ SE
Sbjct: 291 TVGSNERTFDLAVFLKPKVDLK-HEYVVKEGDDVELVCSYHGEGHVTAKFVSGHSEFAVR 349
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
N + G ++++ + +++ E + NS+ T+ T +E L+ E +
Sbjct: 350 N--EAVSAGNSEEIRP---ESNESEEVTTTSENSEETS--TQDEVE----LKSAENVNDE 398
Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
+ + DE + +K+ + + ++ ++ ++ K L I+ + +D +YTC
Sbjct: 399 EDHTSQQDDGEQDEQEESKKWKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCA 458
Query: 1270 LL-DAKSTTKLKVEVVEFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
+ DA + K+ + PP + Y + R G+ V++ D A P P W N K
Sbjct: 459 VSNDAGTVNKVTQVGIIHPPTLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNGKE 518
Query: 1328 IK-KCKHTKPSIDSKSASLTIKKVENTD-AGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
++ + S LT++ + +D G+Y R +N G + +++V + P+ P
Sbjct: 519 VEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQIDVIKVVSPATPS 578
Query: 1386 KPNILEIDSSSINIC-----WDEPENTGNSTIIYYVVEYQEIDTT-EWISVKNIT---KT 1436
N ++ + C E E + T+ V + +E+++ W + ++ +
Sbjct: 579 GMNCKKMVYPNYGKCSFESDIYEKEESKPQTMELLVAKLEEMESDYNWSHAQPVSVPFED 638
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
+I NL +N+ Y +A AVNE S+ SE
Sbjct: 639 DLTIPNLTSNTQYVIKARAVNEAGSSEYSE 668
Score = 50.4 bits (115), Expect = 1e-05
Identities = 47/229 (20%), Positives = 84/229 (36%), Gaps = 7/229 (3%)
Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654
+ +L++ P G + T A+I PP F ++Q+ +EG+ +
Sbjct: 81 SNQLMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIV 140
Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
C + + ++ W F G + DE E + + KK +G Y A
Sbjct: 141 CEVEGTDQLEVFWQFNG--VTLDETSQRGYEFSENNQILYIPHFTAKK-DDGIYNCNAAQ 197
Query: 715 REGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
+L + + TG P V + +G ++ L VG P+PT W +
Sbjct: 198 YSSFETLSVNV---TGYARPTITVFDVPNGNRGIEGHTIELKCGAVGKPKPTYKWFFEDD 254
Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
V + + I++ +D G Y A N+ G E + + V
Sbjct: 255 EVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTFDLAV 303
Score = 46.0 bits (104), Expect = 3e-04
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
+G T++ +C G P+P WF + + ++ + ++ L+I + EDAGT+
Sbjct: 229 EGHTIELKCGAVGKPKPTYKWFFEDDEVPIARSDKHNVEE---GLLIIESLNSEDAGTYK 285
Query: 583 CVAKNAAGFASSTTELIV 600
CVA N G T +L V
Sbjct: 286 CVANNTVGSNERTFDLAV 303
Score = 40.7 bits (91), Expect = 0.011
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
I N+ + + + A N G S S+ + LE T P P AP + M S+ S
Sbjct: 642 IPNLTSNTQYVIKARAVNEAGSS--EYSEEISLE--TTDPWAPQAPGSVAMKCSDYCTVS 697
Query: 1987 WGTPEWDGGAPLLGYNIAIRDV 2008
W TP D G+PLL + + I+++
Sbjct: 698 WDTPN-DHGSPLLKFKVTIQEM 718
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 9/128 (7%)
Query: 789 ITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
I +K ++D YT N G + + + V + PT + P I F +
Sbjct: 441 ILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHYTGP-HIRSF------DG 493
Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKC 906
T+ + V+ P P W++N + + + Q F G + +L + N D + G Y C
Sbjct: 494 NTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTC 553
Query: 907 VASNSAGK 914
A N G+
Sbjct: 554 RADNGVGQ 561
Score = 35.1 bits (77), Expect = 0.55
Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED-AGTF 581
DG+TV C V P P+ WF+ ++ + + + L + D G +
Sbjct: 492 DGNTVSVYCDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVY 551
Query: 582 TCVAKNAAGFASSTTELI-VEAPLSDHG 608
TC A N G ++I V +P + G
Sbjct: 552 TCRADNGVGQLEKQIDVIKVVSPATPSG 579
Score = 32.7 bits (71), Expect = 3.0
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDH 607
++N L I+ + EDA +TC N AG + T++ I+ P H
Sbjct: 436 EENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPPTLRH 482
Score = 32.3 bits (70), Expect = 3.9
Identities = 18/87 (20%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
P F+ +H +G+ + C+VEG + ++ W + + + ++N +
Sbjct: 120 PKFLNVQESQHPEEGTRAEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYI 179
Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTT 596
+D G + C NAA ++S T
Sbjct: 180 PHFTAKKDDGIYNC---NAAQYSSFET 203
>AF022977-1|ABF71715.1| 1285|Caenorhabditis elegans Peroxidasin
(drosophila peroxidase)homolog protein 1 protein.
Length = 1285
Score = 79.0 bits (186), Expect = 3e-14
Identities = 52/189 (27%), Positives = 89/189 (47%), Gaps = 7/189 (3%)
Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
PQ + R+G V ++ +V+GNP+PTI W N K + + G ++++ + P
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYP 374
Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
+D G YT +A NS G + + + ++ PP Q ++ G++ V
Sbjct: 375 FLEEDSGRYTCEAVNSVGKVRHAFSLDL-----ISSVPPNIYEGPQSVSQNLGGSVVFVC 429
Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
+ NPVP TW + I + D + EL I+N++ + D G Y C+A N G
Sbjct: 430 KANGNPVPDYTWSFDGSTIGHIKGRFMVSD-DGTELRISNIEKK-DEGYYSCMAGNPVGA 487
Query: 915 SSHGARVTI 923
S A++T+
Sbjct: 488 MSADAKLTV 496
Score = 74.5 bits (175), Expect = 7e-13
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 14/229 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ KP+ EGS++ + C ++ P+P I W G+ + + + + +
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSN------N 368
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
VL+I + G YT AVN G+ L + + PP + E +S+ G SV+
Sbjct: 369 VLRIYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLIS--SVPPNIYEGPQSVSQNLGGSVV 426
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENS 810
+ GNP P TW + + + + SD T + I +K KDEG Y+ A N
Sbjct: 427 FVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGT-ELRISNIEK-KDEGYYSCMAGNP 484
Query: 811 EGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
G A +TV T + A P + + I K + ++ TR
Sbjct: 485 VGAMSADAKLTVIGGETRKAAAPQIDEELLRAIAQKARQNVENAVEKTR 533
Score = 52.0 bits (119), Expect = 5e-06
Identities = 41/190 (21%), Positives = 81/190 (42%), Gaps = 9/190 (4%)
Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
D++ +PP + P++ + G ++ C+ P PD W F G I + + +
Sbjct: 401 DLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDD 460
Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKS 743
+ L+I+N++K EG Y+ +A N G S L + GE PQ+ E L
Sbjct: 461 G-----TELRISNIEKKDEGYYSCMAGNPVGAMSADAKLTVIGGETRKAAAPQIDEELLR 515
Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
I ++ + +A + T N +K L + ++ + K +++ +E V
Sbjct: 516 AIAQKARQNVENAVEKTRKQLTQDKVTNTNDLKRL-FRFSTPKQAVELSKAREIYEESVR 574
Query: 804 TLKAENSEGI 813
++ +G+
Sbjct: 575 LVREHVEKGL 584
Score = 49.6 bits (113), Expect = 2e-05
Identities = 42/198 (21%), Positives = 76/198 (38%), Gaps = 5/198 (2%)
Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXX 1543
KP N E +E +++ C G P+P + WY +GK+ +++ +
Sbjct: 320 KPRDNSFREGSE-VKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYPFLEE 378
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
Y C A N G+V + + + I +G + G P P+
Sbjct: 379 DSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGNPVPD 438
Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
W +G+ + + K + + + T +RI +++ Y+ A N G S + L V
Sbjct: 439 YTWSFDGSTIGHIKGRFMVSDDGTE-LRISNIEKKDEGYYSCMAGNPVGAMSADAKLTVI 497
Query: 1664 -DKPSKPEGPVIMREISR 1680
+ K P I E+ R
Sbjct: 498 GGETRKAAAPQIDEELLR 515
Score = 45.6 bits (103), Expect = 4e-04
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
+P F K R +GS V+ C+V G P+P I W+ S+ Q+ ++ L
Sbjct: 314 SPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNN---VL 370
Query: 569 VIREVFPEDAGTFTCVAKNAAG 590
I ED+G +TC A N+ G
Sbjct: 371 RIYPFLEEDSGRYTCEAVNSVG 392
Score = 38.7 bits (86), Expect = 0.045
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G +V F C+ G P P TW + I + M DD L I + +D G ++C
Sbjct: 422 GGSVVFVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDDG--TELRISNIEKKDEGYYSC 479
Query: 584 VAKNAAGFASSTTELIV 600
+A N G S+ +L V
Sbjct: 480 MAGNPVGAMSADAKLTV 496
Score = 33.5 bits (73), Expect = 1.7
Identities = 39/176 (22%), Positives = 69/176 (39%), Gaps = 17/176 (9%)
Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGE-IIKPKKNKYDFEKRGHIRKL 1074
P+F K +D +E + E+ + W +G+ I +K + ++ ++
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSN--NVLRI 372
Query: 1075 YIRNTSVHDEGEYSC-----ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129
Y D G Y+C + + + + +PP I Q+ N G F +
Sbjct: 373 Y--PFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCK 430
Query: 1130 LTKGDAL--VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
G+ + W DGS I ++ DG + L+I + + D G YSC GN
Sbjct: 431 -ANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTE--LRISNIEKKDEGYYSCMAGN 483
>AL110479-24|CAJ76966.1| 1084|Caenorhabditis elegans Hypothetical
protein Y105C5B.21b protein.
Length = 1084
Score = 78.6 bits (185), Expect = 5e-14
Identities = 104/426 (24%), Positives = 162/426 (38%), Gaps = 57/426 (13%)
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
PS P P ++ + VT+ W PL G E+ Y IE E + W + +T
Sbjct: 35 PSAPGVPDVV-DAGIGEVTVVWSAPLQSNGGEVRGYQIEMREFPDGEWESMGVDHLLKDT 93
Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK-TALDVPSXXXX-----XXXXXX 1778
C + E FRV A GF A S P+ I + D+ +
Sbjct: 94 TCRVTNLTSHEVQFRVSAYGRTGFGPASNPSLPVKIPISETDLATSAGAPLAPGRPTVIA 153
Query: 1779 IDNESVYITWFPSEKN-GGSPIIDYKVEIKQEGKK-W--KXXXXXXXXXARIQKLSINTT 1834
+D + V + W P + SP Y+VE + G + W ++ L N
Sbjct: 154 VDGQGVLLEWTPPVADVHSSPPQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGV 213
Query: 1835 YQFRIYARNEIGTSLPYTSDDKITI--------------GKTLTPPSQPRNFVVSESTSR 1880
Y+FR+ +N+ G P S + I +++ PP QP+ V +
Sbjct: 214 YEFRVRGKNQDGLGHPSMSSGGVAIRPAAPQRHVPARKVSESVQPPGQPQMVEVGDDV-- 271
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-----TKIVTVG--------GSVHEHCI 1927
V L+W N YI+E++ V W IV G S +E C+
Sbjct: 272 -VKLEWAPSVQN-----ARYIVEYREVGDPEWHTANYDPIVQNGIQVEGLHRNSTYEFCV 325
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
+I D I + S + + PT + S P+ AP + + G I + W
Sbjct: 326 ISI--VDNIASQPSETSDIIHLRPTCNTSAL----RPAPNILEAPEFLEVDGDKITI-CW 378
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTK-TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
P P++GY++ RD+ + W +V V K + DL +H Y R+ A N
Sbjct: 379 -LPA-QSQLPVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNA 436
Query: 2047 IGLSEP 2052
G S+P
Sbjct: 437 SGCSQP 442
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/241 (23%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
+P G M E+ + V +EW P + + +Y +E E + W A+ D V+
Sbjct: 257 QPPGQPQMVEVGDDVVKLEWAPSVQNA-----RYIVEYREVGDPEW-HTANYDPIVQNGI 310
Query: 1728 -IQKLNENCEYMFRVI------AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
++ L+ N Y F VI A P S+ + P +AL +D
Sbjct: 311 QVEGLHRNSTYEFCVISIVDNIASQPSETSDIIHLRPTCNTSALRPAPNILEAPEFLEVD 370
Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXXAR--IQKLSINTTYQ 1836
+ + I W P++ P++ Y VE + Q+ +W + + L ++ YQ
Sbjct: 371 GDKITICWLPAQSQ--LPVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDLIMDHDYQ 428
Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
FR+ A N G S P D + I + S + + S +K+ E E G P
Sbjct: 429 FRVLAHNASGCSQPSPPSDFVHIEPSTNRFSS--DTMESPHLGHHDVVKYVEAERFGAVP 486
Query: 1897 I 1897
+
Sbjct: 487 L 487
Score = 44.4 bits (100), Expect = 0.001
Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNIT 1434
+ + PPG+P ++E+ + + W Y+VEY+E+ EW + I
Sbjct: 252 VSESVQPPGQPQMVEVGDDVVKLEWAPSVQNAR-----YIVEYREVGDPEWHTANYDPIV 306
Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
+ ++ L NS+Y F ++ + S SET++ +I + + +P NI
Sbjct: 307 QNGIQVEGLHRNSTYEFCVISIVDNIASQPSETSD---IIHLRPTCNTSALRPAPNILEA 363
Query: 1495 P 1495
P
Sbjct: 364 P 364
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 3/102 (2%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQT 1438
PS PG P++++ + + W P + + Y +E +E EW + V ++ K T
Sbjct: 35 PSAPGVPDVVDAGIGEVTVVWSAPLQSNGGEVRGYQIEMREFPDGEWESMGVDHLLKDTT 94
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKI 1479
T+ +FR A AS + K+ I ET +
Sbjct: 95 CRVTNLTSHEVQFRVSAYGRTGFGPASNPSLPVKIPISETDL 136
Score = 41.9 bits (94), Expect = 0.005
Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISVKN--ITKTQTSIQNL 1443
P LE+D I ICW ++ ++ Y VE++++ + W V + + + ++ +L
Sbjct: 364 PEFLEVDGDKITICWLPAQS--QLPVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDL 421
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKET-KIQSPTVEKP 1487
+ Y+FR A N S S +++ + T + S T+E P
Sbjct: 422 IMDHDYQFRVLAHNASGCSQPSPPSDFVHIEPSTNRFSSDTMESP 466
Score = 33.9 bits (74), Expect = 1.3
Identities = 27/113 (23%), Positives = 43/113 (38%), Gaps = 5/113 (4%)
Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
P S L + + +PS P P ++ G V W P G + GY I +R+
Sbjct: 20 PPAPASRFLHEDSGIPSAPGVP-DVVDAGIGEVTVVWSAPLQSNGGEVRGYQIEMREFPD 78
Query: 2011 TMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
W +G VD + + +L+ +H R+ A G P K+
Sbjct: 79 GEWESMG-VDHLLKDTTCRVTNLT-SHEVQFRVSAYGRTGFGPASNPSLPVKI 129
>AL110479-23|CAB60320.2| 1254|Caenorhabditis elegans Hypothetical
protein Y105C5B.21a protein.
Length = 1254
Score = 78.6 bits (185), Expect = 5e-14
Identities = 104/426 (24%), Positives = 162/426 (38%), Gaps = 57/426 (13%)
Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
PS P P ++ + VT+ W PL G E+ Y IE E + W + +T
Sbjct: 205 PSAPGVPDVV-DAGIGEVTVVWSAPLQSNGGEVRGYQIEMREFPDGEWESMGVDHLLKDT 263
Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK-TALDVPSXXXX-----XXXXXX 1778
C + E FRV A GF A S P+ I + D+ +
Sbjct: 264 TCRVTNLTSHEVQFRVSAYGRTGFGPASNPSLPVKIPISETDLATSAGAPLAPGRPTVIA 323
Query: 1779 IDNESVYITWFPSEKN-GGSPIIDYKVEIKQEGKK-W--KXXXXXXXXXARIQKLSINTT 1834
+D + V + W P + SP Y+VE + G + W ++ L N
Sbjct: 324 VDGQGVLLEWTPPVADVHSSPPQGYQVEYRVYGSRDWIVANEQLVQENVFTVESLRPNGV 383
Query: 1835 YQFRIYARNEIGTSLPYTSDDKITI--------------GKTLTPPSQPRNFVVSESTSR 1880
Y+FR+ +N+ G P S + I +++ PP QP+ V +
Sbjct: 384 YEFRVRGKNQDGLGHPSMSSGGVAIRPAAPQRHVPARKVSESVQPPGQPQMVEVGDDV-- 441
Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-----TKIVTVG--------GSVHEHCI 1927
V L+W N YI+E++ V W IV G S +E C+
Sbjct: 442 -VKLEWAPSVQN-----ARYIVEYREVGDPEWHTANYDPIVQNGIQVEGLHRNSTYEFCV 495
Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
+I D I + S + + PT + S P+ AP + + G I + W
Sbjct: 496 ISI--VDNIASQPSETSDIIHLRPTCNTSAL----RPAPNILEAPEFLEVDGDKITI-CW 548
Query: 1988 GTPEWDGGAPLLGYNIAIRDVTK-TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
P P++GY++ RD+ + W +V V K + DL +H Y R+ A N
Sbjct: 549 -LPA-QSQLPVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNA 606
Query: 2047 IGLSEP 2052
G S+P
Sbjct: 607 SGCSQP 612
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/241 (23%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
+P G M E+ + V +EW P + + +Y +E E + W A+ D V+
Sbjct: 427 QPPGQPQMVEVGDDVVKLEWAPSVQNA-----RYIVEYREVGDPEW-HTANYDPIVQNGI 480
Query: 1728 -IQKLNENCEYMFRVI------AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
++ L+ N Y F VI A P S+ + P +AL +D
Sbjct: 481 QVEGLHRNSTYEFCVISIVDNIASQPSETSDIIHLRPTCNTSALRPAPNILEAPEFLEVD 540
Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXXAR--IQKLSINTTYQ 1836
+ + I W P++ P++ Y VE + Q+ +W + + L ++ YQ
Sbjct: 541 GDKITICWLPAQSQ--LPVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDLIMDHDYQ 598
Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
FR+ A N G S P D + I + S + + S +K+ E E G P
Sbjct: 599 FRVLAHNASGCSQPSPPSDFVHIEPSTNRFSS--DTMESPHLGHHDVVKYVEAERFGAVP 656
Query: 1897 I 1897
+
Sbjct: 657 L 657
Score = 44.4 bits (100), Expect = 0.001
Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNIT 1434
+ + PPG+P ++E+ + + W Y+VEY+E+ EW + I
Sbjct: 422 VSESVQPPGQPQMVEVGDDVVKLEWAPSVQNAR-----YIVEYREVGDPEWHTANYDPIV 476
Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
+ ++ L NS+Y F ++ + S SET++ +I + + +P NI
Sbjct: 477 QNGIQVEGLHRNSTYEFCVISIVDNIASQPSETSD---IIHLRPTCNTSALRPAPNILEA 533
Query: 1495 P 1495
P
Sbjct: 534 P 534
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 3/102 (2%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQT 1438
PS PG P++++ + + W P + + Y +E +E EW + V ++ K T
Sbjct: 205 PSAPGVPDVVDAGIGEVTVVWSAPLQSNGGEVRGYQIEMREFPDGEWESMGVDHLLKDTT 264
Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKI 1479
T+ +FR A AS + K+ I ET +
Sbjct: 265 CRVTNLTSHEVQFRVSAYGRTGFGPASNPSLPVKIPISETDL 306
Score = 41.9 bits (94), Expect = 0.005
Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISVKN--ITKTQTSIQNL 1443
P LE+D I ICW ++ ++ Y VE++++ + W V + + + ++ +L
Sbjct: 534 PEFLEVDGDKITICWLPAQS--QLPVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDL 591
Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKET-KIQSPTVEKP 1487
+ Y+FR A N S S +++ + T + S T+E P
Sbjct: 592 IMDHDYQFRVLAHNASGCSQPSPPSDFVHIEPSTNRFSSDTMESP 636
Score = 33.9 bits (74), Expect = 1.3
Identities = 27/113 (23%), Positives = 43/113 (38%), Gaps = 5/113 (4%)
Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
P S L + + +PS P P ++ G V W P G + GY I +R+
Sbjct: 190 PPAPASRFLHEDSGIPSAPGVP-DVVDAGIGEVTVVWSAPLQSNGGEVRGYQIEMREFPD 248
Query: 2011 TMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
W +G VD + + +L+ +H R+ A G P K+
Sbjct: 249 GEWESMG-VDHLLKDTTCRVTNLT-SHEVQFRVSAYGRTGFGPASNPSLPVKI 299
>U39667-7|AAP31442.1| 324|Caenorhabditis elegans Disorganized
muscle protein 1,isoform b protein.
Length = 324
Score = 74.1 bits (174), Expect = 1e-12
Identities = 79/320 (24%), Positives = 137/320 (42%), Gaps = 33/320 (10%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDM 688
+G P F ++P A+ D+GS + LEC + A P P + W + +E+ S +
Sbjct: 3 DGKAPHFPQQPVARQNDDGS-LELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGS 61
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
Y ++L I + G Y VN G+ + LK+ TG P V +P S
Sbjct: 62 DSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKL-TGFSSPTFVEKPQISS-RDD 119
Query: 749 GESVILSAQVVGNPRPTITWCK-----------NNKPVKALPTKSDGDTH--SITILKPK 795
G+ +++ + PT W K N+ +KA+ G+ + ++ I +P
Sbjct: 120 GQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPT 179
Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR---FQEITVKEKGTIKL 852
K KD G + +N G + +A TV+ E A P F + Q+ + + I
Sbjct: 180 KDKDAGQFICTVKNESG--KLTATFTVKFEVPEGA--PSFTRKPQILQQTSAGGEPAICF 235
Query: 853 VARVTRNPVPSITWYR-NNEIISPSETI--TQNFDGE---NIELVITNVDSEIDSGDYKC 906
+ P +TW ++ + S I N +G +L +TN ++ DSG Y C
Sbjct: 236 DIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAK-DSGTYTC 294
Query: 907 VASNSAGKSSHGARVTIDVE 926
N AG+++ +T+++E
Sbjct: 295 NIKNDAGEAN--VELTLNIE 312
Score = 64.5 bits (150), Expect = 8e-10
Identities = 81/341 (23%), Positives = 134/341 (39%), Gaps = 44/341 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F ++ + DGS ++ EC V+ P PQ+ W YYD+ V
Sbjct: 6 APHFPQQPVARQNDDGS-LELECFVDANPTPQVKW---------------YYDNKEV--- 46
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
E++G F+ N + S I E +D G+
Sbjct: 47 -------ENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLK 99
Query: 629 LEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW--LFKG--EEIVPDENISVA 683
L G PTF +KP+ D+G +++E R +I EP W L G EEI+ + + A
Sbjct: 100 LTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKA 159
Query: 684 IE--SDMHMYCSVLKITNVKKFQE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
++ ++Y S L+I K ++ G + N G+ + +K + E P +P
Sbjct: 160 VKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPSFTRKP 219
Query: 741 -LKSMIVRQGE-SVILSAQVVGNPRPTITWCK-NNKPVK-----ALPTKSDGDTHSITIL 792
+ GE ++ P +TW +K +K T +G+ + L
Sbjct: 220 QILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQL 279
Query: 793 K--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
+ K KD G YT +N G A + +E P ++ A+
Sbjct: 280 ELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYAD 320
Score = 46.4 bits (105), Expect = 2e-04
Identities = 59/288 (20%), Positives = 117/288 (40%), Gaps = 34/288 (11%)
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF---DGENIELVITNVD-SEIDS 901
+ G+++L V NP P + WY +N+ + S + N ++ ++T + ++ D+
Sbjct: 19 DDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADA 78
Query: 902 GDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960
G Y+C N GK + + + TFV+ Q S ++G+ +++E + + +
Sbjct: 79 GAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQIS-SRDDGQVMVMEFRAKSILEPTF 137
Query: 961 YHNK------KEISGMDHR----EIIQEGRXXXXXXXX---XXXXDVGVIKCIVKDQE-- 1005
K +EI R + ++ G D G C VK++
Sbjct: 138 VWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGK 197
Query: 1006 -TSTMLV---VKETIPEFIRK---LQDFEVKEKDVAILEVEINSE-TADVVW--ERDGEI 1055
T+T V V E P F RK LQ + ++ ++ V W + ++
Sbjct: 198 LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKM 257
Query: 1056 IKPKKNKYDFEKRGH---IRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + K+ G+ +L + N D G Y+C +++++ A V
Sbjct: 258 KESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANV 305
Score = 41.5 bits (93), Expect = 0.006
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Query: 509 APIFVEK---LRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDDDN 564
AP F K L+ + F+ PQ+TW ++ +K S + +D+
Sbjct: 212 APSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEG 271
Query: 565 ----VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
A L + +D+GT+TC KN AG A+ L +E PL D+ +
Sbjct: 272 NGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYADD 321
Score = 39.9 bits (89), Expect = 0.019
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 7/94 (7%)
Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLEN--N 1365
A P P +W ++K ++ ++ DS SA LTIK++ + DAG Y+ + N
Sbjct: 31 ANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHG 90
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
G+A+ + +T P+ KP I D + +
Sbjct: 91 KGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMV 124
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-----TSVIRIKELKRSHSSKYTIEASNT 1650
++ P P+V WY + ++EN ++ K ++++ IKEL + + Y N
Sbjct: 29 VDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNP 88
Query: 1651 AGTSSVEVTLKV--YDKPSKPEGPVIMREISRESVTIEWK 1688
G + LK+ + P+ E P I + + +E++
Sbjct: 89 HGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFR 128
Score = 35.5 bits (78), Expect = 0.42
Identities = 64/277 (23%), Positives = 111/277 (40%), Gaps = 38/277 (13%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
V+W+ D E++ S + K Y L + G +C + + +
Sbjct: 37 VKWYYDNKEVENSGRFSANLANKGSDS--YSAILTIKELADADAGAYRCAIVNPHGKGNA 94
Query: 1197 NFTLRL-----PEFILVP---ANTDAYLTV-EIPDET-LDVTWYKKKSVIEDTEKFTLIS 1246
NF L+L P F+ P + D + V E ++ L+ T+ +K V E+ S
Sbjct: 95 NFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANS 154
Query: 1247 D----VKK--------RTLIIRKCTED-DQCEYTCVLLDAK----STTKLKVEVVEFPPK 1289
D VKK L I++ T+D D ++ C + + +T +K EV E P
Sbjct: 155 DRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPS 214
Query: 1290 IVDYEREYR-IKRGSDVTLLVD--YQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSK---- 1341
+ + G + + D Y A P WI SK +K+ K + +
Sbjct: 215 FTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGN 274
Query: 1342 -SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+A L + + D+G Y ++N+ G A+VE+ + I
Sbjct: 275 FTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNI 311
>U39667-6|AAC69011.2| 640|Caenorhabditis elegans Disorganized
muscle protein 1,isoform a protein.
Length = 640
Score = 74.1 bits (174), Expect = 1e-12
Identities = 79/320 (24%), Positives = 137/320 (42%), Gaps = 33/320 (10%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDM 688
+G P F ++P A+ D+GS + LEC + A P P + W + +E+ S +
Sbjct: 319 DGKAPHFPQQPVARQNDDGS-LELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGS 377
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
Y ++L I + G Y VN G+ + LK+ TG P V +P S
Sbjct: 378 DSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKL-TGFSSPTFVEKPQISS-RDD 435
Query: 749 GESVILSAQVVGNPRPTITWCK-----------NNKPVKALPTKSDGDTH--SITILKPK 795
G+ +++ + PT W K N+ +KA+ G+ + ++ I +P
Sbjct: 436 GQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPT 495
Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR---FQEITVKEKGTIKL 852
K KD G + +N G + +A TV+ E A P F + Q+ + + I
Sbjct: 496 KDKDAGQFICTVKNESG--KLTATFTVKFEVPEGA--PSFTRKPQILQQTSAGGEPAICF 551
Query: 853 VARVTRNPVPSITWYR-NNEIISPSETI--TQNFDGE---NIELVITNVDSEIDSGDYKC 906
+ P +TW ++ + S I N +G +L +TN ++ DSG Y C
Sbjct: 552 DIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAK-DSGTYTC 610
Query: 907 VASNSAGKSSHGARVTIDVE 926
N AG+++ +T+++E
Sbjct: 611 NIKNDAGEAN--VELTLNIE 628
Score = 64.5 bits (150), Expect = 8e-10
Identities = 81/341 (23%), Positives = 134/341 (39%), Gaps = 44/341 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F ++ + DGS ++ EC V+ P PQ+ W YYD+ V
Sbjct: 322 APHFPQQPVARQNDDGS-LELECFVDANPTPQVKW---------------YYDNKEV--- 362
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
E++G F+ N + S I E +D G+
Sbjct: 363 -------ENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLK 415
Query: 629 LEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW--LFKG--EEIVPDENISVA 683
L G PTF +KP+ D+G +++E R +I EP W L G EEI+ + + A
Sbjct: 416 LTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKA 475
Query: 684 IE--SDMHMYCSVLKITNVKKFQE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
++ ++Y S L+I K ++ G + N G+ + +K + E P +P
Sbjct: 476 VKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPSFTRKP 535
Query: 741 -LKSMIVRQGE-SVILSAQVVGNPRPTITWCK-NNKPVK-----ALPTKSDGDTHSITIL 792
+ GE ++ P +TW +K +K T +G+ + L
Sbjct: 536 QILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQL 595
Query: 793 K--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
+ K KD G YT +N G A + +E P ++ A+
Sbjct: 596 ELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYAD 636
Score = 46.4 bits (105), Expect = 2e-04
Identities = 59/288 (20%), Positives = 117/288 (40%), Gaps = 34/288 (11%)
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF---DGENIELVITNVD-SEIDS 901
+ G+++L V NP P + WY +N+ + S + N ++ ++T + ++ D+
Sbjct: 335 DDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADA 394
Query: 902 GDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960
G Y+C N GK + + + TFV+ Q S ++G+ +++E + + +
Sbjct: 395 GAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQIS-SRDDGQVMVMEFRAKSILEPTF 453
Query: 961 YHNK------KEISGMDHR----EIIQEGRXXXXXXXX---XXXXDVGVIKCIVKDQE-- 1005
K +EI R + ++ G D G C VK++
Sbjct: 454 VWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGK 513
Query: 1006 -TSTMLV---VKETIPEFIRK---LQDFEVKEKDVAILEVEINSE-TADVVW--ERDGEI 1055
T+T V V E P F RK LQ + ++ ++ V W + ++
Sbjct: 514 LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKM 573
Query: 1056 IKPKKNKYDFEKRGH---IRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + K+ G+ +L + N D G Y+C +++++ A V
Sbjct: 574 KESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANV 621
Score = 41.5 bits (93), Expect = 0.006
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Query: 509 APIFVEK---LRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDDDN 564
AP F K L+ + F+ PQ+TW ++ +K S + +D+
Sbjct: 528 APSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEG 587
Query: 565 ----VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
A L + +D+GT+TC KN AG A+ L +E PL D+ +
Sbjct: 588 NGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYADD 637
Score = 39.9 bits (89), Expect = 0.019
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 7/94 (7%)
Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLEN--N 1365
A P P +W ++K ++ ++ DS SA LTIK++ + DAG Y+ + N
Sbjct: 347 ANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHG 406
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
G+A+ + +T P+ KP I D + +
Sbjct: 407 KGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMV 440
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-----TSVIRIKELKRSHSSKYTIEASNT 1650
++ P P+V WY + ++EN ++ K ++++ IKEL + + Y N
Sbjct: 345 VDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNP 404
Query: 1651 AGTSSVEVTLKV--YDKPSKPEGPVIMREISRESVTIEWK 1688
G + LK+ + P+ E P I + + +E++
Sbjct: 405 HGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFR 444
Score = 35.5 bits (78), Expect = 0.42
Identities = 64/277 (23%), Positives = 111/277 (40%), Gaps = 38/277 (13%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
V+W+ D E++ S + K Y L + G +C + + +
Sbjct: 353 VKWYYDNKEVENSGRFSANLANKGSDS--YSAILTIKELADADAGAYRCAIVNPHGKGNA 410
Query: 1197 NFTLRL-----PEFILVP---ANTDAYLTV-EIPDET-LDVTWYKKKSVIEDTEKFTLIS 1246
NF L+L P F+ P + D + V E ++ L+ T+ +K V E+ S
Sbjct: 411 NFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANS 470
Query: 1247 D----VKK--------RTLIIRKCTED-DQCEYTCVLLDAK----STTKLKVEVVEFPPK 1289
D VKK L I++ T+D D ++ C + + +T +K EV E P
Sbjct: 471 DRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPS 530
Query: 1290 IVDYEREYR-IKRGSDVTLLVD--YQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSK---- 1341
+ + G + + D Y A P WI SK +K+ K + +
Sbjct: 531 FTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGN 590
Query: 1342 -SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+A L + + D+G Y ++N+ G A+VE+ + I
Sbjct: 591 FTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNI 627
>AY095447-1|AAM23316.1| 640|Caenorhabditis elegans DIM-1(L)
protein.
Length = 640
Score = 74.1 bits (174), Expect = 1e-12
Identities = 79/320 (24%), Positives = 137/320 (42%), Gaps = 33/320 (10%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDM 688
+G P F ++P A+ D+GS + LEC + A P P + W + +E+ S +
Sbjct: 319 DGKAPHFPQQPVARQNDDGS-LELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGS 377
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
Y ++L I + G Y VN G+ + LK+ TG P V +P S
Sbjct: 378 DSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKL-TGFSSPTFVEKPQISS-RDD 435
Query: 749 GESVILSAQVVGNPRPTITWCK-----------NNKPVKALPTKSDGDTH--SITILKPK 795
G+ +++ + PT W K N+ +KA+ G+ + ++ I +P
Sbjct: 436 GQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPT 495
Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR---FQEITVKEKGTIKL 852
K KD G + +N G + +A TV+ E A P F + Q+ + + I
Sbjct: 496 KDKDAGQFICTVKNESG--KLTATFTVKFEVPEGA--PSFTRKPQILQQTSAGGEPAICF 551
Query: 853 VARVTRNPVPSITWYR-NNEIISPSETI--TQNFDGE---NIELVITNVDSEIDSGDYKC 906
+ P +TW ++ + S I N +G +L +TN ++ DSG Y C
Sbjct: 552 DIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAK-DSGTYTC 610
Query: 907 VASNSAGKSSHGARVTIDVE 926
N AG+++ +T+++E
Sbjct: 611 NIKNDAGEAN--VELTLNIE 628
Score = 64.5 bits (150), Expect = 8e-10
Identities = 81/341 (23%), Positives = 134/341 (39%), Gaps = 44/341 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F ++ + DGS ++ EC V+ P PQ+ W YYD+ V
Sbjct: 322 APHFPQQPVARQNDDGS-LELECFVDANPTPQVKW---------------YYDNKEV--- 362
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
E++G F+ N + S I E +D G+
Sbjct: 363 -------ENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLK 415
Query: 629 LEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW--LFKG--EEIVPDENISVA 683
L G PTF +KP+ D+G +++E R +I EP W L G EEI+ + + A
Sbjct: 416 LTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKA 475
Query: 684 IE--SDMHMYCSVLKITNVKKFQE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
++ ++Y S L+I K ++ G + N G+ + +K + E P +P
Sbjct: 476 VKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPSFTRKP 535
Query: 741 -LKSMIVRQGE-SVILSAQVVGNPRPTITWCK-NNKPVK-----ALPTKSDGDTHSITIL 792
+ GE ++ P +TW +K +K T +G+ + L
Sbjct: 536 QILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQL 595
Query: 793 K--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
+ K KD G YT +N G A + +E P ++ A+
Sbjct: 596 ELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYAD 636
Score = 46.4 bits (105), Expect = 2e-04
Identities = 59/288 (20%), Positives = 117/288 (40%), Gaps = 34/288 (11%)
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF---DGENIELVITNVD-SEIDS 901
+ G+++L V NP P + WY +N+ + S + N ++ ++T + ++ D+
Sbjct: 335 DDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADA 394
Query: 902 GDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960
G Y+C N GK + + + TFV+ Q S ++G+ +++E + + +
Sbjct: 395 GAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQIS-SRDDGQVMVMEFRAKSILEPTF 453
Query: 961 YHNK------KEISGMDHR----EIIQEGRXXXXXXXX---XXXXDVGVIKCIVKDQE-- 1005
K +EI R + ++ G D G C VK++
Sbjct: 454 VWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGK 513
Query: 1006 -TSTMLV---VKETIPEFIRK---LQDFEVKEKDVAILEVEINSE-TADVVW--ERDGEI 1055
T+T V V E P F RK LQ + ++ ++ V W + ++
Sbjct: 514 LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKM 573
Query: 1056 IKPKKNKYDFEKRGH---IRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + K+ G+ +L + N D G Y+C +++++ A V
Sbjct: 574 KESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANV 621
Score = 41.5 bits (93), Expect = 0.006
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Query: 509 APIFVEK---LRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDDDN 564
AP F K L+ + F+ PQ+TW ++ +K S + +D+
Sbjct: 528 APSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEG 587
Query: 565 ----VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
A L + +D+GT+TC KN AG A+ L +E PL D+ +
Sbjct: 588 NGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYADD 637
Score = 39.9 bits (89), Expect = 0.019
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 7/94 (7%)
Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLEN--N 1365
A P P +W ++K ++ ++ DS SA LTIK++ + DAG Y+ + N
Sbjct: 347 ANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHG 406
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
G+A+ + +T P+ KP I D + +
Sbjct: 407 KGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMV 440
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-----TSVIRIKELKRSHSSKYTIEASNT 1650
++ P P+V WY + ++EN ++ K ++++ IKEL + + Y N
Sbjct: 345 VDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNP 404
Query: 1651 AGTSSVEVTLKV--YDKPSKPEGPVIMREISRESVTIEWK 1688
G + LK+ + P+ E P I + + +E++
Sbjct: 405 HGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFR 444
Score = 35.5 bits (78), Expect = 0.42
Identities = 64/277 (23%), Positives = 111/277 (40%), Gaps = 38/277 (13%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
V+W+ D E++ S + K Y L + G +C + + +
Sbjct: 353 VKWYYDNKEVENSGRFSANLANKGSDS--YSAILTIKELADADAGAYRCAIVNPHGKGNA 410
Query: 1197 NFTLRL-----PEFILVP---ANTDAYLTV-EIPDET-LDVTWYKKKSVIEDTEKFTLIS 1246
NF L+L P F+ P + D + V E ++ L+ T+ +K V E+ S
Sbjct: 411 NFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANS 470
Query: 1247 D----VKK--------RTLIIRKCTED-DQCEYTCVLLDAK----STTKLKVEVVEFPPK 1289
D VKK L I++ T+D D ++ C + + +T +K EV E P
Sbjct: 471 DRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPS 530
Query: 1290 IVDYEREYR-IKRGSDVTLLVD--YQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSK---- 1341
+ + G + + D Y A P WI SK +K+ K + +
Sbjct: 531 FTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGN 590
Query: 1342 -SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+A L + + D+G Y ++N+ G A+VE+ + I
Sbjct: 591 FTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNI 627
>AF500489-1|AAM21705.1| 324|Caenorhabditis elegans DIM-1 short
protein isoform protein.
Length = 324
Score = 74.1 bits (174), Expect = 1e-12
Identities = 79/320 (24%), Positives = 137/320 (42%), Gaps = 33/320 (10%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDM 688
+G P F ++P A+ D+GS + LEC + A P P + W + +E+ S +
Sbjct: 3 DGKAPHFPQQPVARQNDDGS-LELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGS 61
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
Y ++L I + G Y VN G+ + LK+ TG P V +P S
Sbjct: 62 DSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKL-TGFSSPTFVEKPQISS-RDD 119
Query: 749 GESVILSAQVVGNPRPTITWCK-----------NNKPVKALPTKSDGDTH--SITILKPK 795
G+ +++ + PT W K N+ +KA+ G+ + ++ I +P
Sbjct: 120 GQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPT 179
Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR---FQEITVKEKGTIKL 852
K KD G + +N G + +A TV+ E A P F + Q+ + + I
Sbjct: 180 KDKDAGQFICTVKNESG--KLTATFTVKFEVPEGA--PSFTRKPQILQQTSAGGEPAICF 235
Query: 853 VARVTRNPVPSITWYR-NNEIISPSETI--TQNFDGE---NIELVITNVDSEIDSGDYKC 906
+ P +TW ++ + S I N +G +L +TN ++ DSG Y C
Sbjct: 236 DIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAK-DSGTYTC 294
Query: 907 VASNSAGKSSHGARVTIDVE 926
N AG+++ +T+++E
Sbjct: 295 NIKNDAGEAN--VELTLNIE 312
Score = 64.5 bits (150), Expect = 8e-10
Identities = 81/341 (23%), Positives = 134/341 (39%), Gaps = 44/341 (12%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
AP F ++ + DGS ++ EC V+ P PQ+ W YYD+ V
Sbjct: 6 APHFPQQPVARQNDDGS-LELECFVDANPTPQVKW---------------YYDNKEV--- 46
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
E++G F+ N + S I E +D G+
Sbjct: 47 -------ENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLK 99
Query: 629 LEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW--LFKG--EEIVPDENISVA 683
L G PTF +KP+ D+G +++E R +I EP W L G EEI+ + + A
Sbjct: 100 LTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANSDRIKA 159
Query: 684 IE--SDMHMYCSVLKITNVKKFQE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
++ ++Y S L+I K ++ G + N G+ + +K + E P +P
Sbjct: 160 VKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPSFTRKP 219
Query: 741 -LKSMIVRQGE-SVILSAQVVGNPRPTITWCK-NNKPVK-----ALPTKSDGDTHSITIL 792
+ GE ++ P +TW +K +K T +G+ + L
Sbjct: 220 QILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQL 279
Query: 793 K--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
+ K KD G YT +N G A + +E P ++ A+
Sbjct: 280 ELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYAD 320
Score = 46.4 bits (105), Expect = 2e-04
Identities = 59/288 (20%), Positives = 117/288 (40%), Gaps = 34/288 (11%)
Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF---DGENIELVITNVD-SEIDS 901
+ G+++L V NP P + WY +N+ + S + N ++ ++T + ++ D+
Sbjct: 19 DDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADA 78
Query: 902 GDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960
G Y+C N GK + + + TFV+ Q S ++G+ +++E + + +
Sbjct: 79 GAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQIS-SRDDGQVMVMEFRAKSILEPTF 137
Query: 961 YHNK------KEISGMDHR----EIIQEGRXXXXXXXX---XXXXDVGVIKCIVKDQE-- 1005
K +EI R + ++ G D G C VK++
Sbjct: 138 VWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGK 197
Query: 1006 -TSTMLV---VKETIPEFIRK---LQDFEVKEKDVAILEVEINSE-TADVVW--ERDGEI 1055
T+T V V E P F RK LQ + ++ ++ V W + ++
Sbjct: 198 LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKM 257
Query: 1056 IKPKKNKYDFEKRGH---IRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
+ + K+ G+ +L + N D G Y+C +++++ A V
Sbjct: 258 KESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANV 305
Score = 41.5 bits (93), Expect = 0.006
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Query: 509 APIFVEK---LRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDDDN 564
AP F K L+ + F+ PQ+TW ++ +K S + +D+
Sbjct: 212 APSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEG 271
Query: 565 ----VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
A L + +D+GT+TC KN AG A+ L +E PL D+ +
Sbjct: 272 NGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNIEGPLDDYADD 321
Score = 39.9 bits (89), Expect = 0.019
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 7/94 (7%)
Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLEN--N 1365
A P P +W ++K ++ ++ DS SA LTIK++ + DAG Y+ + N
Sbjct: 31 ANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNPHG 90
Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
G+A+ + +T P+ KP I D + +
Sbjct: 91 KGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMV 124
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-----TSVIRIKELKRSHSSKYTIEASNT 1650
++ P P+V WY + ++EN ++ K ++++ IKEL + + Y N
Sbjct: 29 VDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILTIKELADADAGAYRCAIVNP 88
Query: 1651 AGTSSVEVTLKV--YDKPSKPEGPVIMREISRESVTIEWK 1688
G + LK+ + P+ E P I + + +E++
Sbjct: 89 HGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFR 128
Score = 35.5 bits (78), Expect = 0.42
Identities = 64/277 (23%), Positives = 111/277 (40%), Gaps = 38/277 (13%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
V+W+ D E++ S + K Y L + G +C + + +
Sbjct: 37 VKWYYDNKEVENSGRFSANLANKGSDS--YSAILTIKELADADAGAYRCAIVNPHGKGNA 94
Query: 1197 NFTLRL-----PEFILVP---ANTDAYLTV-EIPDET-LDVTWYKKKSVIEDTEKFTLIS 1246
NF L+L P F+ P + D + V E ++ L+ T+ +K V E+ S
Sbjct: 95 NFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRAKSILEPTFVWQKLVGGGAEEIIANS 154
Query: 1247 D----VKK--------RTLIIRKCTED-DQCEYTCVLLDAK----STTKLKVEVVEFPPK 1289
D VKK L I++ T+D D ++ C + + +T +K EV E P
Sbjct: 155 DRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFICTVKNESGKLTATFTVKFEVPEGAPS 214
Query: 1290 IVDYEREYR-IKRGSDVTLLVD--YQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSK---- 1341
+ + G + + D Y A P WI SK +K+ K + +
Sbjct: 215 FTRKPQILQQTSAGGEPAICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGN 274
Query: 1342 -SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+A L + + D+G Y ++N+ G A+VE+ + I
Sbjct: 275 FTAQLELTNYKAKDSGTYTCNIKNDAGEANVELTLNI 311
>Z54236-7|CAA90982.1| 1471|Caenorhabditis elegans Hypothetical protein
C27B7.7 protein.
Length = 1471
Score = 71.3 bits (167), Expect = 7e-12
Identities = 122/529 (23%), Positives = 204/529 (38%), Gaps = 52/529 (9%)
Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVI 1630
V T +E+ + + +T ++ + V+W NG K+ D Y + T I
Sbjct: 247 VKTEPDEEYTADPQTNEPLSITCTVKSVSKASVLWKVNGIKVSVDSSFYTVVTSVHEDFI 306
Query: 1631 R--IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
I+ R+ S+K+T A+N AG SS EV + + S P ++ E + TI WK
Sbjct: 307 ESTIRAKSRTRSAKFTCLATNDAGDSSKEVNVIIKGPGSPPSEITLVAE--KRGYTISWK 364
Query: 1689 PPLDDGGLELTKYAIE---KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745
PP G ++TKY + E + W K+ D+D + I E Y RV A
Sbjct: 365 PPSHPNG-KITKYVVYHTLNREDPLSDWRKI-DLDGSEKMVRIIMDTEESFY-GRVQAAT 421
Query: 1746 PVG---FSE--ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS-PI 1799
+G S+ A+E + I D+ + S+ T + S I
Sbjct: 422 ELGPGIISDIVAMERDTQPISVESDLFGVSATTMVVNPRETLSIQCTARGKPRPSISVAI 481
Query: 1800 IDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
D K + E W + + S+ T+ A+N G++ S ++
Sbjct: 482 SDRKNASQVEVDVWSRLQATSSAGIVSAVHNFSVLTSKFVHCRAKNSAGSNY---STMEL 538
Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
+ K P P V + + W P+ SPIT+YI+ + + +
Sbjct: 539 KVDK---PGDAPTQIQVLSVNALDALVVWHSPQF-PNSPITSYIVLVSNDDKEDKSTWLQ 594
Query: 1918 VGGSVHEHCIE-------NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
+ E I N+++ E + A+N G+ PT S + + SPP
Sbjct: 595 YESNAKETQINRMLLPTGNLEKSTEYFVCVRAKNAAGIG-PTSSLISFITLNGGPDSPPD 653
Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
L++ + +N V+ W TP + + GY I T + + D +F +
Sbjct: 654 -NLKVLINEANQVIVYWNTP--NSTTEVTGYLIYY-----TRDLSLSNDDYKNWQF--VE 703
Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKV-IPGEGSHADEEPGEQTE 2078
++ N T R + LS L+ ++V I G+ SHAD E E
Sbjct: 704 MNNNST-------RYKFDLSVGLKPKTFYRVRISGKNSHADGPASEVVE 745
Score = 54.4 bits (125), Expect = 8e-07
Identities = 83/385 (21%), Positives = 152/385 (39%), Gaps = 25/385 (6%)
Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
ID + I + ++G NN G + + + +L +PP + IL + I
Sbjct: 925 IDDTTVVSKITRNNIRESGDLTCLANNNEGSSSASVEIRVLGPGNPP-ENIILTAYRNQI 983
Query: 1398 NICWDEPENTGNSTIIYYVVEYQEI---DTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
N+ W E N I+ Y+V Y E D ++W + + +T ++ ++ + R
Sbjct: 984 NVTWQE-STLPNGDIMKYIVYYSENENDDLSDWNKFET-AELETYVETFGPHTKHFIRVQ 1041
Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
AV++ S + I V + + EPN+++E+ C G PQP++
Sbjct: 1042 AVSDRGPGIISNVLSCISDVLYETIHLEIVASNILDFEAEPNQNVEIRCKGTGKPQPEL- 1100
Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXX----XXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
+Y+ + + E C A N + V S V+ I ++
Sbjct: 1101 FYQFANETEQNFVEVETNDMDLFEAKAPEINSRRNVTVTCRASNKYENVTISKVI-IIKR 1159
Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSV 1629
P +N I + +E+ T I P I NG KLE N N TK
Sbjct: 1160 PGEAPTN--ISWSFE--EEYDSTLYINWNP----IENANGEKLEYNLYLSNYKTKVSGPP 1211
Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRES-VTIEW 1687
++I ++ + + A N G + + P+ P++ +++S V I W
Sbjct: 1212 VKIPDIPLDVNISLRVSAENEYGEGEKTFPIWIPTPNGGPKTAPILSSLHAQDSKVYIFW 1271
Query: 1688 -KPPLDDGGLE-LTKYAIEKHEPDN 1710
+P L +G ++ T Y +++E +N
Sbjct: 1272 VEPRLPNGEIQNYTIYIQKENESEN 1296
Score = 48.4 bits (110), Expect = 6e-05
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 13/176 (7%)
Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE----YNITTKEKTSVIRIKEL 1635
I+++ + +E VT G P P + W +EN E NI + T V +I
Sbjct: 878 IEKEPNLFEELSVTCTGMGSPAPIITWEWMNKSIENGTEGWNILNIQIDDTTVVSKITRN 937
Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
S T A+N G+SS V ++V + PE I+ R + + W+ G
Sbjct: 938 NIRESGDLTCLANNNEGSSSASVEIRVLGPGNPPEN--IILTAYRNQINVTWQESTLPNG 995
Query: 1696 LELTKYAI---EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
++ KY + E D + W K ++ETY ++ + ++ RV A + G
Sbjct: 996 -DIMKYIVYYSENENDDLSDWNKFETA--ELETY-VETFGPHTKHFIRVQAVSDRG 1047
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/173 (20%), Positives = 71/173 (41%), Gaps = 7/173 (4%)
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
TI+ T + + N+ G + E+NV I SPP + ++ + I W P
Sbjct: 309 TIRAKSRTRSAKFTCLATNDAGDSSKEVNVIIKGPGSPPSEITLVA-EKRGYTISWKPPS 367
Query: 1406 NTGNSTIIYYVVEY---QEIDTTEWISVKNITKTQTSIQNLK-TNSSYRFRAYAVNEVDI 1461
+ N I YVV + +E ++W + ++ ++ ++ + T S+ R A E+
Sbjct: 368 HP-NGKITKYVVYHTLNREDPLSDWRKI-DLDGSEKMVRIIMDTEESFYGRVQAATELGP 425
Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
S+ + + ++S + P E + + C G P+P ++
Sbjct: 426 GIISDIVAMERDTQPISVESDLFGVSATTMVVNPRETLSIQCTARGKPRPSIS 478
Score = 35.9 bits (79), Expect = 0.32
Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 9/71 (12%)
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI------DSGDYKCVASNSA 912
+P P ITW N+ I E T+ ++ NI++ T V S+I +SGD C+A+N+
Sbjct: 897 SPAPIITWEWMNKSI---ENGTEGWNILNIQIDDTTVVSKITRNNIRESGDLTCLANNNE 953
Query: 913 GKSSHGARVTI 923
G SS + +
Sbjct: 954 GSSSASVEIRV 964
Score = 35.5 bits (78), Expect = 0.42
Identities = 53/260 (20%), Positives = 100/260 (38%), Gaps = 26/260 (10%)
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTI--KKVENTDAGIYKLRLE---NNCGHADVE 1372
ND N + +K H + + S + I K E +Y++R NN
Sbjct: 79 NDSSQTNEEY-EKWMHQEALSNQNSYNFVIDANKHEIVSGDVYRVRATVFFNNVESVPTG 137
Query: 1373 MNVTILDKPSPPGKPNILE---IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
+ ++I + S P P I+ + +SS+ I + ++ + I Y + Y++++ EW S
Sbjct: 138 V-ISINTRQSIPKAPLIVNTKILYNSSVLISFVPADDV--NAIENYTLMYKQMEAEEWKS 194
Query: 1430 V--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487
+ K+ + + L N +Y + + + S + T + E P
Sbjct: 195 LNFKSDFDGKVLLDGLIPNHTYEIKIFVTGGIVQGTPSNLATF--TTNSTALALVKTE-P 251
Query: 1488 LKNITTEP--NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXX 1538
+ T +P NE + +TC V + V W +G K+ + Y E+
Sbjct: 252 DEEYTADPQTNEPLSITCTVKSVSKASVLWKVNGIKVSVDSSFYTVVTSVHEDFIESTIR 311
Query: 1539 XXXXXXXXXYKCIAFNDHGE 1558
+ C+A ND G+
Sbjct: 312 AKSRTRSAKFTCLATNDAGD 331
Score = 34.3 bits (75), Expect = 0.97
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 5/77 (6%)
Query: 531 CQVEGYPRPQITWFRQTAIIKPSQD----FQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
C G P P ITW I+ + + DD V + + R E +G TC+A
Sbjct: 892 CTGMGSPAPIITWEWMNKSIENGTEGWNILNIQIDDTTVVSKITRNNIRE-SGDLTCLAN 950
Query: 587 NAAGFASSTTELIVEAP 603
N G +S++ E+ V P
Sbjct: 951 NNEGSSSASVEIRVLGP 967
Score = 33.9 bits (74), Expect = 1.3
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 8/106 (7%)
Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNST--IIYYV--VEYQEIDTTEWISVK---NIT 1434
SPP +L +++ + + W+ P +T T +IYY + D W V+ N T
Sbjct: 650 SPPDNLKVLINEANQVIVYWNTPNSTTEVTGYLIYYTRDLSLSNDDYKNWQFVEMNNNST 709
Query: 1435 KTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
+ + + LK + YR R N ASE E+ E I
Sbjct: 710 RYKFDLSVGLKPKTFYRVRISGKNSHADGPASEVVEFETAYSEVPI 755
Score = 31.5 bits (68), Expect = 6.8
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 8/83 (9%)
Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVK-------ALPTKSDGDTHSITILKPKKVKDEGV 802
E + ++ +G+P P ITW NK ++ L + D DT ++ + +++ G
Sbjct: 886 EELSVTCTGMGSPAPIITWEWMNKSIENGTEGWNILNIQID-DTTVVSKITRNNIRESGD 944
Query: 803 YTLKAENSEGIAETSAVITVEEP 825
T A N+EG + S I V P
Sbjct: 945 LTCLANNNEGSSSASVEIRVLGP 967
>U67954-5|AAM54179.1| 444|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform b
protein.
Length = 444
Score = 70.5 bits (165), Expect = 1e-11
Identities = 77/281 (27%), Positives = 109/281 (38%), Gaps = 22/281 (7%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDMHMYCSVLKITNVKKF 703
EG + L C V P I W E + D+ I E M SVL I V+
Sbjct: 31 EGESLTLRCE-VEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPI 89
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGE-SVILSAQVV-G 760
Y+ E E S+ V+K++ +P VI P + R GE +++++ V G
Sbjct: 90 NSANYSCALA--EPEVSVTFVIKVQV---KPLVVISPDTGVYHARVGEKNLVITCHVKEG 144
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
NP+P + W K + + G I I + KK G Y AEN G + I
Sbjct: 145 NPKPGVVWTKQAAKLPEDIKREHGGAR-IVITEVKK-HHAGKYNCLAENIAGSDRATIDI 202
Query: 821 TVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW----YR---NNEI 872
V EP + E E P N I V++ PVP + W Y+ N+E
Sbjct: 203 HVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEK 262
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+ Q +G + + SE GDY C SN G
Sbjct: 263 FKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG 303
Score = 56.0 bits (129), Expect = 3e-07
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLEN 1615
EV + V+ +Q KP++ IS + +VG++ LV V EG P P V+W K KL
Sbjct: 102 EVSVTFVIKVQVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPE 161
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD--KPSKPEGPV 1673
D I + + I I E+K+ H+ KY A N AG+ + + V + + + E P
Sbjct: 162 D----IKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREEKPW 217
Query: 1674 IMRE 1677
+ E
Sbjct: 218 VKNE 221
Score = 44.8 bits (101), Expect = 7e-04
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
Query: 531 CQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
C V EG P+P + W +Q A K +D + + A +VI EV AG + C+A+N A
Sbjct: 139 CHVKEGNPKPGVVWTKQAA--KLPEDIKREHGG---ARIVITEVKKHHAGKYNCLAENIA 193
Query: 590 GFASSTTELIVEAPLSDHGSE 610
G +T ++ V PL E
Sbjct: 194 GSDRATIDIHVAEPLQGEREE 214
Score = 38.7 bits (86), Expect = 0.045
Identities = 40/191 (20%), Positives = 70/191 (36%), Gaps = 21/191 (10%)
Query: 1497 EDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+++ +TC + G P+P V W + KL Y C+A N
Sbjct: 133 KNLVITCHVKEGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENI 192
Query: 1556 HGEVETSCVVGI--------QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
G + + + ++KP + NED + +G P P+V W
Sbjct: 193 AGSDRATIDIHVAEPLQGEREEKP--WVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWL 250
Query: 1608 KNGNKLE-NDKEYNITTKE-------KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
NG K+ ND+++ T++ S + + ++ Y SN G SV
Sbjct: 251 FNGYKINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG--SVTAV 308
Query: 1660 LKVYDKPSKPE 1670
+ V +P P+
Sbjct: 309 VHVSGRPGPPQ 319
Score = 37.1 bits (82), Expect = 0.14
Identities = 50/298 (16%), Positives = 116/298 (38%), Gaps = 43/298 (14%)
Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-------QLTIDGKKQKLKIYDCDLDD 1172
+G T E+ + W K+ + + I +++++G L I + +
Sbjct: 31 EGESLTLRCEVEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPIN 90
Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
+ YSC + + + ++ +++ +++ +T Y + ++ L +T + K
Sbjct: 91 SANYSCALAEPEVSVTFVIK-------VQVKPLVVISPDTGVY-HARVGEKNLVITCHVK 142
Query: 1233 KS-----VIEDTEKFTLISDVKKR----TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+ V+ + L D+K+ ++I + + +Y C+ + + + +++
Sbjct: 143 EGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDI 202
Query: 1284 V---------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KI------ 1327
E P + + + +++ + + Y P P EW+ N KI
Sbjct: 203 HVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEK 262
Query: 1328 IKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
KK T ++ S S LT+ + G Y R+ N G ++V+ +P PP
Sbjct: 263 FKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTAVVHVS--GRPGPP 318
Score = 31.1 bits (67), Expect = 9.0
Identities = 17/83 (20%), Positives = 35/83 (42%)
Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
I +K + + ++ A N A+ + ++ + + P V+ I N++
Sbjct: 174 ITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNA 233
Query: 1500 ELTCIFGGVPQPKVTWYRDGKKL 1522
C + G P P+V W +G K+
Sbjct: 234 SFWCTYDGTPVPQVEWLFNGYKI 256
>AF456363-1|AAL60234.1| 443|Caenorhabditis elegans immunoglobulin
domain-containingprotein WRK-1B protein.
Length = 443
Score = 70.5 bits (165), Expect = 1e-11
Identities = 77/281 (27%), Positives = 109/281 (38%), Gaps = 22/281 (7%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDMHMYCSVLKITNVKKF 703
EG + L C V P I W E + D+ I E M SVL I V+
Sbjct: 30 EGESLTLRCE-VEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPI 88
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGE-SVILSAQVV-G 760
Y+ E E S+ V+K++ +P VI P + R GE +++++ V G
Sbjct: 89 NSANYSCALA--EPEVSVTFVIKVQV---KPLVVISPDTGVYHARVGEKNLVITCHVKEG 143
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
NP+P + W K + + G I I + KK G Y AEN G + I
Sbjct: 144 NPKPGVVWTKQAAKLPEDIKREHGGAR-IVITEVKK-HHAGKYNCLAENIAGSDRATIDI 201
Query: 821 TVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW----YR---NNEI 872
V EP + E E P N I V++ PVP + W Y+ N+E
Sbjct: 202 HVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEK 261
Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+ Q +G + + SE GDY C SN G
Sbjct: 262 FKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG 302
Score = 56.0 bits (129), Expect = 3e-07
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLEN 1615
EV + V+ +Q KP++ IS + +VG++ LV V EG P P V+W K KL
Sbjct: 101 EVSVTFVIKVQVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPE 160
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD--KPSKPEGPV 1673
D I + + I I E+K+ H+ KY A N AG+ + + V + + + E P
Sbjct: 161 D----IKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREEKPW 216
Query: 1674 IMRE 1677
+ E
Sbjct: 217 VKNE 220
Score = 44.8 bits (101), Expect = 7e-04
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
Query: 531 CQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
C V EG P+P + W +Q A K +D + + A +VI EV AG + C+A+N A
Sbjct: 138 CHVKEGNPKPGVVWTKQAA--KLPEDIKREHGG---ARIVITEVKKHHAGKYNCLAENIA 192
Query: 590 GFASSTTELIVEAPLSDHGSE 610
G +T ++ V PL E
Sbjct: 193 GSDRATIDIHVAEPLQGEREE 213
Score = 38.7 bits (86), Expect = 0.045
Identities = 40/191 (20%), Positives = 70/191 (36%), Gaps = 21/191 (10%)
Query: 1497 EDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+++ +TC + G P+P V W + KL Y C+A N
Sbjct: 132 KNLVITCHVKEGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENI 191
Query: 1556 HGEVETSCVVGI--------QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
G + + + ++KP + NED + +G P P+V W
Sbjct: 192 AGSDRATIDIHVAEPLQGEREEKP--WVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWL 249
Query: 1608 KNGNKLE-NDKEYNITTKE-------KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
NG K+ ND+++ T++ S + + ++ Y SN G SV
Sbjct: 250 FNGYKINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG--SVTAV 307
Query: 1660 LKVYDKPSKPE 1670
+ V +P P+
Sbjct: 308 VHVSGRPGPPQ 318
Score = 37.1 bits (82), Expect = 0.14
Identities = 50/298 (16%), Positives = 116/298 (38%), Gaps = 43/298 (14%)
Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-------QLTIDGKKQKLKIYDCDLDD 1172
+G T E+ + W K+ + + I +++++G L I + +
Sbjct: 30 EGESLTLRCEVEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPIN 89
Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
+ YSC + + + ++ +++ +++ +T Y + ++ L +T + K
Sbjct: 90 SANYSCALAEPEVSVTFVIK-------VQVKPLVVISPDTGVY-HARVGEKNLVITCHVK 141
Query: 1233 KS-----VIEDTEKFTLISDVKKR----TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+ V+ + L D+K+ ++I + + +Y C+ + + + +++
Sbjct: 142 EGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDI 201
Query: 1284 V---------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KI------ 1327
E P + + + +++ + + Y P P EW+ N KI
Sbjct: 202 HVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEK 261
Query: 1328 IKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
KK T ++ S S LT+ + G Y R+ N G ++V+ +P PP
Sbjct: 262 FKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTAVVHVS--GRPGPP 317
Score = 31.1 bits (67), Expect = 9.0
Identities = 17/83 (20%), Positives = 35/83 (42%)
Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
I +K + + ++ A N A+ + ++ + + P V+ I N++
Sbjct: 173 ITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNA 232
Query: 1500 ELTCIFGGVPQPKVTWYRDGKKL 1522
C + G P P+V W +G K+
Sbjct: 233 SFWCTYDGTPVPQVEWLFNGYKI 255
>U67954-6|AAV28344.1| 452|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform e
protein.
Length = 452
Score = 67.7 bits (158), Expect = 8e-11
Identities = 77/286 (26%), Positives = 110/286 (38%), Gaps = 24/286 (8%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDMHMYCSVLKITNVKKF 703
EG + L C V P I W E + D+ I E M SVL I V+
Sbjct: 31 EGESLTLRCE-VEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPI 89
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEK-----EPPQVIEPLKSMI-VRQGE-SVILSA 756
Y+ E E S+ V+K++ + +P VI P + R GE +++++
Sbjct: 90 NSANYSCALA--EPEVSVTFVIKVQVFKPTQVSVKPLVVISPDTGVYHARVGEKNLVITC 147
Query: 757 QVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
V GNP+P + W K + + G I I + KK G Y AEN G
Sbjct: 148 HVKEGNPKPGVVWTKQAAKLPEDIKREHGGAR-IVITEVKK-HHAGKYNCLAENIAGSDR 205
Query: 816 TSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW----YR-- 868
+ I V EP + E E P N I V++ PVP + W Y+
Sbjct: 206 ATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKIN 265
Query: 869 -NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
N+E + Q +G + + SE GDY C SN G
Sbjct: 266 FNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG 311
Score = 48.8 bits (111), Expect = 4e-05
Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
+ KP++ IS + +VG++ LV V EG P P V+W K KL D I +
Sbjct: 119 VSVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPED----IKRE 174
Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD--KPSKPEGPVIMRE 1677
+ I I E+K+ H+ KY A N AG+ + + V + + + E P + E
Sbjct: 175 HGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREEKPWVKNE 229
Score = 44.8 bits (101), Expect = 7e-04
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
Query: 531 CQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
C V EG P+P + W +Q A K +D + + A +VI EV AG + C+A+N A
Sbjct: 147 CHVKEGNPKPGVVWTKQAA--KLPEDIKREHGG---ARIVITEVKKHHAGKYNCLAENIA 201
Query: 590 GFASSTTELIVEAPLSDHGSE 610
G +T ++ V PL E
Sbjct: 202 GSDRATIDIHVAEPLQGEREE 222
Score = 39.5 bits (88), Expect = 0.026
Identities = 51/299 (17%), Positives = 116/299 (38%), Gaps = 37/299 (12%)
Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-------QLTIDGKKQKLKIYDCDLDD 1172
+G T E+ + W K+ + + I +++++G L I + +
Sbjct: 31 EGESLTLRCEVEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPIN 90
Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
+ YSC + + + ++ T + + +++ +T Y + ++ L +T +
Sbjct: 91 SANYSCALAEPEVSVTFVIKVQVFKPTQVSVKPLVVISPDTGVY-HARVGEKNLVITCHV 149
Query: 1232 KKS-----VIEDTEKFTLISDVKKR----TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
K+ V+ + L D+K+ ++I + + +Y C+ + + + ++
Sbjct: 150 KEGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATID 209
Query: 1283 VV---------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KI----- 1327
+ E P + + + +++ + + Y P P EW+ N KI
Sbjct: 210 IHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDE 269
Query: 1328 -IKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
KK T ++ S S LT+ + G Y R+ N G ++V+ +P PP
Sbjct: 270 KFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTAVVHVS--GRPGPP 326
Score = 38.7 bits (86), Expect = 0.045
Identities = 40/191 (20%), Positives = 70/191 (36%), Gaps = 21/191 (10%)
Query: 1497 EDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+++ +TC + G P+P V W + KL Y C+A N
Sbjct: 141 KNLVITCHVKEGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENI 200
Query: 1556 HGEVETSCVVGI--------QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
G + + + ++KP + NED + +G P P+V W
Sbjct: 201 AGSDRATIDIHVAEPLQGEREEKP--WVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWL 258
Query: 1608 KNGNKLE-NDKEYNITTKE-------KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
NG K+ ND+++ T++ S + + ++ Y SN G SV
Sbjct: 259 FNGYKINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG--SVTAV 316
Query: 1660 LKVYDKPSKPE 1670
+ V +P P+
Sbjct: 317 VHVSGRPGPPQ 327
Score = 31.1 bits (67), Expect = 9.0
Identities = 17/83 (20%), Positives = 35/83 (42%)
Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
I +K + + ++ A N A+ + ++ + + P V+ I N++
Sbjct: 182 ITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNA 241
Query: 1500 ELTCIFGGVPQPKVTWYRDGKKL 1522
C + G P P+V W +G K+
Sbjct: 242 SFWCTYDGTPVPQVEWLFNGYKI 264
>AY714779-1|AAU14146.1| 1338|Caenorhabditis elegans UNC-89 protein.
Length = 1338
Score = 64.9 bits (151), Expect = 6e-10
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
+++ I+K+ +++ + APIF +LR + FEC V P P++TW
Sbjct: 852 ERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDF 911
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
Q I++ S D D+NVA L++ P D G + C A N G S+ LI
Sbjct: 912 QGKILE-SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI 964
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAE---PPLFINRFQEITVKE 846
L+PK + KA ++ I A I P T++N + P+F R +++ +++
Sbjct: 830 LEPKSHEQSTALLQKAPSATAIERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRK 889
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
V+ +P P +TW +I+ ++ +T D N+ +I N + D G+Y C
Sbjct: 890 NQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQD-NNVARLILNHAAPYDLGEYVC 948
Query: 907 VASNSAGKSSHGARV 921
A N G R+
Sbjct: 949 TAINEYGTDKSSCRL 963
Score = 48.8 bits (111), Expect = 4e-05
Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 8/169 (4%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ P P+V W G LE++ I + + + +Y A N GT
Sbjct: 899 VSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDK 958
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNN--- 1711
L + PS+P P E+S ++ + I+W+ P LE Y +E N
Sbjct: 959 SSCRLISGETPSRPGRP--EAELSSDTEIFIQWEAPEGPTYLEGITYRLEYRVAGPNDHG 1016
Query: 1712 -RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
WI V++ D E+ ++ L+ Y FRV AQN G S IV
Sbjct: 1017 DPWITVSE-KIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIV 1064
Score = 47.2 bits (107), Expect = 1e-04
Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 5/177 (2%)
Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
F P R+ +++ A P P W KI++ D+ A L
Sbjct: 874 FAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARL 933
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
+ D G Y N G + + PS PG+P + I I W+ PE
Sbjct: 934 ILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPE 993
Query: 1406 NTGNSTIIYYVVEYQEIDTTE----WISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
I Y +EY+ + WI+V + I +++L Y+FR A N
Sbjct: 994 GPTYLEGITYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQN 1050
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ + + Y+ + + EC + A P P + W F+G+ + + N V IE D ++ +
Sbjct: 876 PIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGK--ILESNDRVTIEQDNNV--A 931
Query: 694 VLKITNVKKFQEGTYTVVAVNREG 717
L + + + G Y A+N G
Sbjct: 932 RLILNHAAPYDLGEYVCTAINEYG 955
Score = 35.5 bits (78), Expect = 0.42
Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 4/87 (4%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYE---NRXXXX 1536
+P L+++ N+ C P PKVTW GK L++ + T E N
Sbjct: 875 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 934
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSC 1563
Y C A N++G ++SC
Sbjct: 935 LNHAAPYDLGEYVCTAINEYGTDKSSC 961
Score = 31.1 bits (67), Expect = 9.0
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 15/123 (12%)
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
A NE GT S ++ G+T + P +P + S++ + ++W PE Y
Sbjct: 950 AINEYGTD---KSSCRLISGETPSRPGRPEAELSSDT---EIFIQWEAPEGPTYLEGITY 1003
Query: 1901 IIEFKTV----KGKSWTKIVTVGGSVHEHCI--ENIKEKDEIIFRISAENTVGVSLPTES 1954
+E++ G W +TV + + + +++ FR++A+N G+ LP+ S
Sbjct: 1004 RLEYRVAGPNDHGDPW---ITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLS 1060
Query: 1955 QSV 1957
+
Sbjct: 1061 SRI 1063
>AF003131-8|AAP68959.1| 1393|Caenorhabditis elegans Uncoordinated
protein 89, isoform c protein.
Length = 1393
Score = 64.9 bits (151), Expect = 6e-10
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
+++ I+K+ +++ + APIF +LR + FEC V P P++TW
Sbjct: 816 ERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDF 875
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
Q I++ S D D+NVA L++ P D G + C A N G S+ LI
Sbjct: 876 QGKILE-SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI 928
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAE---PPLFINRFQEITVKE 846
L+PK + KA ++ I A I P T++N + P+F R +++ +++
Sbjct: 794 LEPKSHEQSTALLQKAPSATAIERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRK 853
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
V+ +P P +TW +I+ ++ +T D N+ +I N + D G+Y C
Sbjct: 854 NQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQD-NNVARLILNHAAPYDLGEYVC 912
Query: 907 VASNSAGKSSHGARV 921
A N G R+
Sbjct: 913 TAINEYGTDKSSCRL 927
Score = 48.8 bits (111), Expect = 4e-05
Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 8/169 (4%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ P P+V W G LE++ I + + + +Y A N GT
Sbjct: 863 VSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDK 922
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNN--- 1711
L + PS+P P E+S ++ + I+W+ P LE Y +E N
Sbjct: 923 SSCRLISGETPSRPGRP--EAELSSDTEIFIQWEAPEGPTYLEGITYRLEYRVAGPNDHG 980
Query: 1712 -RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
WI V++ D E+ ++ L+ Y FRV AQN G S IV
Sbjct: 981 DPWITVSE-KIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIV 1028
Score = 47.2 bits (107), Expect = 1e-04
Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 5/177 (2%)
Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
F P R+ +++ A P P W KI++ D+ A L
Sbjct: 838 FAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARL 897
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
+ D G Y N G + + PS PG+P + I I W+ PE
Sbjct: 898 ILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPE 957
Query: 1406 NTGNSTIIYYVVEYQEIDTTE----WISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
I Y +EY+ + WI+V + I +++L Y+FR A N
Sbjct: 958 GPTYLEGITYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQN 1014
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ + + Y+ + + EC + A P P + W F+G+ + + N V IE D ++ +
Sbjct: 840 PIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGK--ILESNDRVTIEQDNNV--A 895
Query: 694 VLKITNVKKFQEGTYTVVAVNREG 717
L + + + G Y A+N G
Sbjct: 896 RLILNHAAPYDLGEYVCTAINEYG 919
Score = 35.5 bits (78), Expect = 0.42
Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 4/87 (4%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYE---NRXXXX 1536
+P L+++ N+ C P PKVTW GK L++ + T E N
Sbjct: 839 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 898
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSC 1563
Y C A N++G ++SC
Sbjct: 899 LNHAAPYDLGEYVCTAINEYGTDKSSC 925
Score = 31.1 bits (67), Expect = 9.0
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 15/123 (12%)
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
A NE GT S ++ G+T + P +P + S++ + ++W PE Y
Sbjct: 914 AINEYGTD---KSSCRLISGETPSRPGRPEAELSSDT---EIFIQWEAPEGPTYLEGITY 967
Query: 1901 IIEFKTV----KGKSWTKIVTVGGSVHEHCI--ENIKEKDEIIFRISAENTVGVSLPTES 1954
+E++ G W +TV + + + +++ FR++A+N G+ LP+ S
Sbjct: 968 RLEYRVAGPNDHGDPW---ITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLS 1024
Query: 1955 QSV 1957
+
Sbjct: 1025 SRI 1027
>AF003131-7|AAV34798.1| 1396|Caenorhabditis elegans Uncoordinated
protein 89, isoform d protein.
Length = 1396
Score = 64.9 bits (151), Expect = 6e-10
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
+++ I+K+ +++ + APIF +LR + FEC V P P++TW
Sbjct: 819 ERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDF 878
Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
Q I++ S D D+NVA L++ P D G + C A N G S+ LI
Sbjct: 879 QGKILE-SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI 931
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAE---PPLFINRFQEITVKE 846
L+PK + KA ++ I A I P T++N + P+F R +++ +++
Sbjct: 797 LEPKSHEQSTALLQKAPSATAIERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRK 856
Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
V+ +P P +TW +I+ ++ +T D N+ +I N + D G+Y C
Sbjct: 857 NQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQD-NNVARLILNHAAPYDLGEYVC 915
Query: 907 VASNSAGKSSHGARV 921
A N G R+
Sbjct: 916 TAINEYGTDKSSCRL 930
Score = 48.8 bits (111), Expect = 4e-05
Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 8/169 (4%)
Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
+ P P+V W G LE++ I + + + +Y A N GT
Sbjct: 866 VSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDK 925
Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNN--- 1711
L + PS+P P E+S ++ + I+W+ P LE Y +E N
Sbjct: 926 SSCRLISGETPSRPGRP--EAELSSDTEIFIQWEAPEGPTYLEGITYRLEYRVAGPNDHG 983
Query: 1712 -RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
WI V++ D E+ ++ L+ Y FRV AQN G S IV
Sbjct: 984 DPWITVSE-KIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIV 1031
Score = 47.2 bits (107), Expect = 1e-04
Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 5/177 (2%)
Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
F P R+ +++ A P P W KI++ D+ A L
Sbjct: 841 FAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARL 900
Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
+ D G Y N G + + PS PG+P + I I W+ PE
Sbjct: 901 ILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPE 960
Query: 1406 NTGNSTIIYYVVEYQEIDTTE----WISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
I Y +EY+ + WI+V + I +++L Y+FR A N
Sbjct: 961 GPTYLEGITYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQN 1017
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F+ + + Y+ + + EC + A P P + W F+G+ + + N V IE D ++ +
Sbjct: 843 PIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGK--ILESNDRVTIEQDNNV--A 898
Query: 694 VLKITNVKKFQEGTYTVVAVNREG 717
L + + + G Y A+N G
Sbjct: 899 RLILNHAAPYDLGEYVCTAINEYG 922
Score = 35.5 bits (78), Expect = 0.42
Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 4/87 (4%)
Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYE---NRXXXX 1536
+P L+++ N+ C P PKVTW GK L++ + T E N
Sbjct: 842 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 901
Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSC 1563
Y C A N++G ++SC
Sbjct: 902 LNHAAPYDLGEYVCTAINEYGTDKSSC 928
Score = 31.1 bits (67), Expect = 9.0
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 15/123 (12%)
Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
A NE GT S ++ G+T + P +P + S++ + ++W PE Y
Sbjct: 917 AINEYGTD---KSSCRLISGETPSRPGRPEAELSSDT---EIFIQWEAPEGPTYLEGITY 970
Query: 1901 IIEFKTV----KGKSWTKIVTVGGSVHEHCI--ENIKEKDEIIFRISAENTVGVSLPTES 1954
+E++ G W +TV + + + +++ FR++A+N G+ LP+ S
Sbjct: 971 RLEYRVAGPNDHGDPW---ITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLS 1027
Query: 1955 QSV 1957
+
Sbjct: 1028 SRI 1030
>U41530-1|AAA83273.3| 636|Caenorhabditis elegans Hypothetical
protein SSSD1.1 protein.
Length = 636
Score = 64.5 bits (150), Expect = 8e-10
Identities = 71/307 (23%), Positives = 134/307 (43%), Gaps = 52/307 (16%)
Query: 626 ADILEGIPPTFSKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
A ++ +PP K + + G+D++ EC+ P P+I W + E+I+
Sbjct: 32 AKLVVNVPPVIISPSKNAIIHKKVGADLIFECKAEGAPSPEITWS-RNEQIISTS----- 85
Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
VL ++N+++ +G YT +AVN EG ++ I ++ K + PL
Sbjct: 86 ---------PVLTLSNLEEGDKGLYTCLAVNIEGNSTSSIDVRFT---KATILDLIPLNK 133
Query: 744 MIVRQGESVILSAQVVGNPRP-TITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDE 800
++ +G +V + +W KP+K +L +S+ + +++ +K D
Sbjct: 134 TVI-EGSNVFWHCHANAQATAISYSWLFEKKPIKTTSLGLRSNIRSGDLSLQDVRK-SDS 191
Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
G YT +A+NS G V TV P+ EI V+ + + + +P
Sbjct: 192 GWYTCEAKNSAGETTKPPVFTVAPPS--------------EIKVRLGDQVSIPCQGFGDP 237
Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
+P + W R+ + I+ S T+T + +E +D G Y+CV +NS S
Sbjct: 238 MPIVYWIRDKKRINQS-TLT----FKKVE--------HLDHGAYECVVANSVETISTRVM 284
Query: 921 VTIDVEK 927
+ +++ K
Sbjct: 285 LLVEITK 291
Score = 60.1 bits (139), Expect = 2e-08
Identities = 79/305 (25%), Positives = 122/305 (40%), Gaps = 69/305 (22%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
H G+ + FEC+ EG P P+ITW R II S L + + D G
Sbjct: 52 HKKVGADLIFECKAEGAPSPEITWSRNEQIISTSP------------VLTLSNLEEGDKG 99
Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
+TC+A N G +ST+ + V A IL+ IP
Sbjct: 100 LYTCLAVNIEG--NSTSSIDVR---------------------FTKATILDLIPLN---- 132
Query: 640 PKAQYVDEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
+ V EGS++ C A +WLF+ + P + S+ + S++ L +
Sbjct: 133 ---KTVIEGSNVFWHCHANAQATAISYSWLFEKK---PIKTTSLGLRSNIRS--GDLSLQ 184
Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+V+K G YT A N GE + P V + PP I+ VR G+ V + Q
Sbjct: 185 DVRKSDSGWYTCEAKNSAGETTKPPVFTVA-----PPSEIK------VRLGDQVSIPCQG 233
Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
G+P P + W ++ K + + ++T K + + D G Y NS T
Sbjct: 234 FGDPMPIVYWIRDKKRI---------NQSTLTFKKVEHL-DHGAYECVVANSVETISTRV 283
Query: 819 VITVE 823
++ VE
Sbjct: 284 MLLVE 288
Score = 58.8 bits (136), Expect = 4e-08
Identities = 91/384 (23%), Positives = 155/384 (40%), Gaps = 47/384 (12%)
Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151
R E + VV +PP II+ +N ++K A E A EI +S +
Sbjct: 25 RPEKGLSAKLVVNVPPVIISPSKNAIIHKKVGADLIFECKAEGA------PSPEITWSRN 78
Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFIL 1207
Q+ L + + + D G Y+C GNS + + + +I + L + ++
Sbjct: 79 EQII--STSPVLTLSNLEEGDKGLYTCLAVNIEGNSTSSIDVRFTKATILDLIPLNKTVI 136
Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
+N + + +W +K I+ T L S+++ L ++ + D YT
Sbjct: 137 EGSNVFWHCHANAQATAISYSWLFEKKPIKTTS-LGLRSNIRSGDLSLQDVRKSDSGWYT 195
Query: 1268 CVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
C + A TTK V V PP E +++ G V++ P P WI + K
Sbjct: 196 CEAKNSAGETTKPPVFTVA-PPS------EIKVRLGDQVSIPCQGFGDPMPIVYWIRDKK 248
Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-LDKPSPPG 1385
I + ++LT KKVE+ D G Y+ + N+ + + + + KP
Sbjct: 249 RINQ------------STLTFKKVEHLDHGAYECVVANSVETISTRVMLLVEITKPQMAS 296
Query: 1386 KPNILEIDSSSINICW-DEPEN----TGNSTIIY-------YVVEYQEIDTTEWISVKNI 1433
++SSS+ I W + EN GN Y + V Q T +W S+K
Sbjct: 297 SIKFTCLNSSSMRISWTPDSENHFLKPGNERKGYNGGFDQTFAVHAQNDVTLQWTSIKT- 355
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVN 1457
+ +T + +L+ SYR +VN
Sbjct: 356 SLNETILDHLEPFVSYRVSIESVN 379
Score = 48.0 bits (109), Expect = 7e-05
Identities = 65/252 (25%), Positives = 98/252 (38%), Gaps = 32/252 (12%)
Query: 1283 VVEFPPKIVDYEREYRI--KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
VV PP I+ + I K G+D+ + P P W N +II S
Sbjct: 35 VVNVPPVIISPSKNAIIHKKVGADLIFECKAEGAPSPEITWSRNEQII-----------S 83
Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINI 1399
S LT+ +E D G+Y N G++ ++V P N I+ S N+
Sbjct: 84 TSPVLTLSNLEEGDKGLYTCLAVNIEGNSTSSIDVRFTKATILDLIPLNKTVIEGS--NV 141
Query: 1400 CWDEPENTGNSTIIY-YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
W N + I Y ++ E + I TT NI S+Q+++ + S + A N
Sbjct: 142 FWHCHANAQATAISYSWLFEKKPIKTTSLGLRSNIRSGDLSLQDVRKSDSGWYTCEAKNS 201
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
A ETT K TV P I + + + C G P P V W RD
Sbjct: 202 -----AGETT---------KPPVFTVAPP-SEIKVRLGDQVSIPCQGFGDPMPIVYWIRD 246
Query: 1519 GKKLKTAKATYE 1530
K++ + T++
Sbjct: 247 KKRINQSTLTFK 258
Score = 46.0 bits (104), Expect = 3e-04
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 19/141 (13%)
Query: 832 PPLFINRFQEITVKEKGTIKLV--ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
PP+ I+ + + +K L+ + P P ITW RN +IIS S +T + N+E
Sbjct: 39 PPVIISPSKNAIIHKKVGADLIFECKAEGAPSPEITWSRNEQIISTSPVLTLS----NLE 94
Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
E D G Y C+A N G S+ + + + K T + + + EG V
Sbjct: 95 --------EGDKGLYTCLAVNIEGNST--SSIDVRFTKATILDLIPLNKTVIEGSNVFWH 144
Query: 950 CQT---SHTVSTKWYHNKKEI 967
C + +S W KK I
Sbjct: 145 CHANAQATAISYSWLFEKKPI 165
Score = 32.7 bits (71), Expect = 3.0
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 13/90 (14%)
Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
PVI +++ KVG + + EG P PE+ W +N E I+T + V+
Sbjct: 40 PVIISPSKNAIIHKKVGADLIFECKAEGAPSPEITWSRN--------EQIIST---SPVL 88
Query: 1631 RIKELKRSHSSKYTIEASNTAG--TSSVEV 1658
+ L+ YT A N G TSS++V
Sbjct: 89 TLSNLEEGDKGLYTCLAVNIEGNSTSSIDV 118
>AC006695-2|AAM48553.1| 724|Caenorhabditis elegans Temporarily
assigned gene nameprotein 58, isoform a protein.
Length = 724
Score = 64.5 bits (150), Expect = 8e-10
Identities = 55/232 (23%), Positives = 99/232 (42%), Gaps = 26/232 (11%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI- 789
E+ P+++EPL S G+++ L ++ NP + W K++ V+ D T +
Sbjct: 412 EECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLD 471
Query: 790 ----TILKPK-KVKDEGVYTLKAENSEGIAETSAVITVEE----PTEENAE--------- 831
+L P+ +D G+Y A N G AET+A I VE E AE
Sbjct: 472 GGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDHEEAEISESVLTDD 531
Query: 832 -----PPLFINRFQEIT--VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
PP FI T ++ G +++VA V +++W ++ I +E
Sbjct: 532 VHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMDIYENEKYEVMQF 591
Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
+ +++ + +DSG Y C A + G S+ +V + + + + +K
Sbjct: 592 ADGAQILTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELTISAESSPESFEK 643
Score = 53.2 bits (122), Expect = 2e-06
Identities = 51/249 (20%), Positives = 96/249 (38%), Gaps = 17/249 (6%)
Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQ 557
P + + AP VE L DG + C++ P + W + ++ ++D
Sbjct: 407 PPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVT 466
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXX 615
D V L+ E F EDAG + C A N G A + + VE + DH E +
Sbjct: 467 TTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDH-EEAEISE 525
Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQ--YVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
D+ +PP F + A+ + + + + ++ ++W G +
Sbjct: 526 SVLTD------DVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMD 579
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
I +E V +D ++ TN+ G YT A + G ++ +++ +
Sbjct: 580 IYENEKYEVMQFADGAQILTIRAPTNL---DSGVYTCTAESEHGVSNSSCQVELTISAES 636
Query: 734 PPQVIEPLK 742
P+ E ++
Sbjct: 637 SPESFEKVE 645
Score = 48.0 bits (109), Expect = 7e-05
Identities = 54/243 (22%), Positives = 97/243 (39%), Gaps = 22/243 (9%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP+ I+ +K+ V +++ L +V +P W N K V + H I I +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVG-HGINISR 147
Query: 794 PKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENA-----------------EPPLF 835
K + ++GVY N G++ + ITV E + + P F
Sbjct: 148 LKVSRPEQGVYKCVTRNPAGVSTSYGYITVNADREHLSSSKEDMRLQRQHSVTYHQAPRF 207
Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
+ + + V + + V NP +W+ N + S + F ++ +
Sbjct: 208 LTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMF-SPDVNRSVVRF 266
Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT 955
+ +G+YK VASN G + V I E+ T K + E ++ I+E + S T
Sbjct: 267 SIPV-AGEYKVVASNVHGSAMSCGHVDIQKERRTDGKLEKFQIEFKKKLVQIIELEES-T 324
Query: 956 VST 958
++T
Sbjct: 325 LTT 327
Score = 48.0 bits (109), Expect = 7e-05
Identities = 87/454 (19%), Positives = 172/454 (37%), Gaps = 40/454 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVATL 568
P F++ ++ T+ +V P WF + ++++ FQ+ + N++ L
Sbjct: 90 PKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVGHGI-NISRL 148
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
+ PE G + CV +N AG ++S + V A +H + +
Sbjct: 149 KVSR--PEQ-GVYKCVTRNPAGVSTSYGYITVNAD-REH-----LSSSKEDMRLQRQHSV 199
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
P F + +V GS+++++ + A P +W G+E + D+
Sbjct: 200 TYHQAPRFLTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMFSPDV 259
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEAS----LPIVLKIKTGEKEPPQVIEPLKSM 744
+ SV++ + G Y VVA N G A + I + +T K IE K +
Sbjct: 260 NR--SVVRFSIPVA---GEYKVVASNVHGSAMSCGHVDIQKERRTDGKLEKFQIEFKKKL 314
Query: 745 --IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT----------KSDGDTHSITIL 792
I+ ES + ++ +P T N + +S + L
Sbjct: 315 VQIIELEESTLTTSTTAFDPMTTSMRALGNNGRNSRQAVNMFELNYTQRSSSVPRGVRHL 374
Query: 793 KPK-KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
+ +V + K + + + + P P + + + +
Sbjct: 375 ESHIEVSNMTGEEKKTQQQTRTGDDDSSFEIVPPNLPEECAPKIVEPLHSASFLDGQAMS 434
Query: 852 LVARVTRNPVPSITWYRNN----EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
L ++T NP ++ W +++ + + + T DG EL+ +E D+G YKC
Sbjct: 435 LRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCELLNPECFAE-DAGLYKCT 493
Query: 908 ASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
A+N G + A I+VE ++K +++ +E
Sbjct: 494 ATNPHGTAETAA--FINVEGAEYIKDHEEAEISE 525
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PPK + + YR+ ++L+V+ + P EW N K + + + +++
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQV--GHGINIS 146
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
KV + G+YK N G
Sbjct: 147 RLKVSRPEQGVYKCVTRNPAG 167
Score = 33.1 bits (72), Expect = 2.2
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 11/135 (8%)
Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
+ A + + P V W K+G + EN+K + + ++ I+ S YT A +
Sbjct: 559 MVATVRSVAPITVSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESE 618
Query: 1651 AGTSS----VEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGLELTKYA-I 1703
G S+ VE+T+ P E I E+ + + + L + E++ A I
Sbjct: 619 HGVSNSSCQVELTISAESSPESFEKVEITPPEEVKETGIDDDIEVILKE---EVSGTAQI 675
Query: 1704 EKHEPDNNRWIKVAD 1718
EK E + +KVAD
Sbjct: 676 EKREEEFKLLVKVAD 690
Score = 32.7 bits (71), Expect = 3.0
Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 9/104 (8%)
Query: 1093 DESCTAEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQ 1147
D+ + E+ LP P+I+ L + G + ++T A V W KD ++
Sbjct: 398 DDDSSFEIVPPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVE 457
Query: 1148 ---FSNHIQLTI-DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
+ + T+ DG +L +C +DAG Y C N TA
Sbjct: 458 DWVLNKDVTTTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTA 501
>AC006695-1|AAU45229.1| 703|Caenorhabditis elegans Temporarily
assigned gene nameprotein 58, isoform b protein.
Length = 703
Score = 64.5 bits (150), Expect = 8e-10
Identities = 55/232 (23%), Positives = 99/232 (42%), Gaps = 26/232 (11%)
Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI- 789
E+ P+++EPL S G+++ L ++ NP + W K++ V+ D T +
Sbjct: 391 EECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLD 450
Query: 790 ----TILKPK-KVKDEGVYTLKAENSEGIAETSAVITVEE----PTEENAE--------- 831
+L P+ +D G+Y A N G AET+A I VE E AE
Sbjct: 451 GGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDHEEAEISESVLTDD 510
Query: 832 -----PPLFINRFQEIT--VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
PP FI T ++ G +++VA V +++W ++ I +E
Sbjct: 511 VHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMDIYENEKYEVMQF 570
Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
+ +++ + +DSG Y C A + G S+ +V + + + + +K
Sbjct: 571 ADGAQILTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELTISAESSPESFEK 622
Score = 53.2 bits (122), Expect = 2e-06
Identities = 90/443 (20%), Positives = 174/443 (39%), Gaps = 39/443 (8%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVATL 568
P F++ ++ T+ +V P WF + ++++ FQ+ + N++ L
Sbjct: 90 PKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVGHGI-NISRL 148
Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
+ PE G + CV +N AG ++S + V A +H + +
Sbjct: 149 KVSR--PEQ-GVYKCVTRNPAGVSTSYGYITVNAD-REH-----LSSSKEDMRLQRQHSV 199
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
P F + +V GS+++++ + A P +W G+E + D+
Sbjct: 200 TYHQAPRFLTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMFSPDV 259
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ SV++ + G Y VVA N G A + G + +VIE +S +
Sbjct: 260 NR--SVVRFSIPVA---GEYKVVASNVHGSA-------MSCGHVDIQKVIELEESTLTTS 307
Query: 749 G---ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD---GDTHSITILKPKKVKDEGV 802
+ + S + +GN N + S G H + ++ + E
Sbjct: 308 TTAFDPMTTSMRALGNNGRNSRQAVNMFELNYTQRSSSVPRGVRHLESHIEVSNMTGEEK 367
Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
T + + G ++S I EE A P + + + + L ++T NP
Sbjct: 368 KT-QQQTRTGDDDSSFEIVPPNLPEECA--PKIVEPLHSASFLDGQAMSLRCKITANPSA 424
Query: 863 SITWYRNN----EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
++ W +++ + + + T DG EL+ +E D+G YKC A+N G +
Sbjct: 425 AVVWSKDDVNVEDWVLNKDVTTTVLDGGVCELLNPECFAE-DAGLYKCTATNPHGTAETA 483
Query: 919 ARVTIDVEKVTFVKHLQKSYETE 941
A I+VE ++K +++ +E
Sbjct: 484 A--FINVEGAEYIKDHEEAEISE 504
Score = 53.2 bits (122), Expect = 2e-06
Identities = 51/249 (20%), Positives = 96/249 (38%), Gaps = 17/249 (6%)
Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQ 557
P + + AP VE L DG + C++ P + W + ++ ++D
Sbjct: 386 PPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVT 445
Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXX 615
D V L+ E F EDAG + C A N G A + + VE + DH E +
Sbjct: 446 TTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDH-EEAEISE 504
Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQ--YVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
D+ +PP F + A+ + + + + ++ ++W G +
Sbjct: 505 SVLTD------DVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMD 558
Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
I +E V +D ++ TN+ G YT A + G ++ +++ +
Sbjct: 559 IYENEKYEVMQFADGAQILTIRAPTNL---DSGVYTCTAESEHGVSNSSCQVELTISAES 615
Query: 734 PPQVIEPLK 742
P+ E ++
Sbjct: 616 SPESFEKVE 624
Score = 46.0 bits (104), Expect = 3e-04
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
PP FI + V TI LV V +P W+ N + + Q G NI +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVGHGINISRL 148
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
S + G YKCV N AG S+ +T++ ++ +HL S E
Sbjct: 149 KV---SRPEQGVYKCVTRNPAGVSTSYGYITVNADR----EHLSSSKE 189
Score = 44.8 bits (101), Expect = 7e-04
Identities = 47/213 (22%), Positives = 84/213 (39%), Gaps = 23/213 (10%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
PP+ I+ +K+ V +++ L +V +P W N K V + H I I +
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQVG-HGINISR 147
Query: 794 PKKVK-DEGVYTLKAENSEGIAETSAVITVEEPTEENA-----------------EPPLF 835
K + ++GVY N G++ + ITV E + + P F
Sbjct: 148 LKVSRPEQGVYKCVTRNPAGVSTSYGYITVNADREHLSSSKEDMRLQRQHSVTYHQAPRF 207
Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
+ + + V + + V NP +W+ N + S + F ++ +
Sbjct: 208 LTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMF-SPDVNRSVVRF 266
Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
+ +G+YK VASN G + V D++KV
Sbjct: 267 SIPV-AGEYKVVASNVHGSAMSCGHV--DIQKV 296
Score = 38.3 bits (85), Expect = 0.059
Identities = 87/469 (18%), Positives = 170/469 (36%), Gaps = 64/469 (13%)
Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
+ GS+V + V+ A P W VN K + H S + ++ + AG Y
Sbjct: 216 VTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMF-SPDVNRSVVRFSIPVAGEY 274
Query: 1359 KLRLEN------NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
K+ N +CGH D++ V L++ + + ++S+ + N+ +
Sbjct: 275 KVVASNVHGSAMSCGHVDIQ-KVIELEESTLTTSTTAFDPMTTSMRALGNNGRNS-RQAV 332
Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
+ + Y + ++ V+++ ++ + N+ + + D S ++
Sbjct: 333 NMFELNYTQRSSSVPRGVRHL-ESHIEVSNMTGEEKKTQQQTRTGDDDSS--------FE 383
Query: 1473 VIKETKIQ--SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK------- 1523
++ + +P + +PL + + + + L C P V W +D ++
Sbjct: 384 IVPPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKD 443
Query: 1524 -TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE-DIK 1581
T YKC A N HG ET+ + ++ I E +I
Sbjct: 444 VTTTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTAETAAFINVEGAEYIKDHEEAEIS 503
Query: 1582 QKHKVGDEWLV------------------------TAVIEGIPPPEVIWYKNGNKL-END 1616
+ D ++ A + + P V W K+G + EN+
Sbjct: 504 ESVLTDDVHIILPPKFIETLTAETDNFQQLGYVRMVATVRSVAPITVSWQKDGMDIYENE 563
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS----VEVTLKVYDKPSKPEGP 1672
K + + ++ I+ S YT A + G S+ VE+T+ P E
Sbjct: 564 KYEVMQFADGAQILTIRAPTNLDSGVYTCTAESEHGVSNSSCQVELTISAESSPESFEKV 623
Query: 1673 VIM--REISRESVTIEWKPPLDDGGLELTKYA-IEKHEPDNNRWIKVAD 1718
I E+ + + + L + E++ A IEK E + +KVAD
Sbjct: 624 EITPPEEVKETGIDDDIEVILKE---EVSGTAQIEKREEEFKLLVKVAD 669
Score = 34.3 bits (75), Expect = 0.97
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
PPK + + YR+ ++L+V+ + P EW N K + + + +++
Sbjct: 89 PPKFIQVIKAYRVHSTDTISLVVEVASDPPAIFEWFYNEKSVLQDRDRFQV--GHGINIS 146
Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
KV + G+YK N G
Sbjct: 147 RLKVSRPEQGVYKCVTRNPAG 167
Score = 32.7 bits (71), Expect = 3.0
Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 9/104 (8%)
Query: 1093 DESCTAEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQ 1147
D+ + E+ LP P+I+ L + G + ++T A V W KD ++
Sbjct: 377 DDDSSFEIVPPNLPEECAPKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVE 436
Query: 1148 ---FSNHIQLTI-DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
+ + T+ DG +L +C +DAG Y C N TA
Sbjct: 437 DWVLNKDVTTTVLDGGVCELLNPECFAEDAGLYKCTATNPHGTA 480
Score = 31.1 bits (67), Expect = 9.0
Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS-QDFQMYYDDDNVAT 567
AP F+ ++ GS V + +V+ P + +WF + S +M+ D N +
Sbjct: 204 APRFLTQVPNLFVTAGSNVIIDVEVDANPPARFSWFVNGKEYRDSIHGVEMFSPDVNRS- 262
Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
V+R P AG + VA N G A S + ++ + S +T
Sbjct: 263 -VVRFSIPV-AGEYKVVASNVHGSAMSCGHVDIQKVIELEESTLT 305
>U00054-3|AAM48546.1| 12268|Caenorhabditis elegans Hypothetical
protein K07E12.1b protein.
Length = 12268
Score = 63.3 bits (147), Expect = 2e-09
Identities = 90/398 (22%), Positives = 155/398 (38%), Gaps = 46/398 (11%)
Query: 1395 SSINICWDEP-ENTG--NSTIIYYVVEYQEIDTTEW--ISVK-----NITKTQTSIQNLK 1444
+++NI W P + G S +Y+ EY + D W ISV + + +
Sbjct: 1046 NTVNITWSPPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFN 1105
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
N+ Y+ R A N++ AS+ + E + T++ T EP +TC
Sbjct: 1106 PNTPYKIRISATNDLSEGPASDPVRFETGSGEIP-PTITLDPSNSTYTVEPLGAATITCT 1164
Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
GVPQPKV W KA E C+A N+ G+ + +
Sbjct: 1165 ATGVPQPKVHW---------IKANGETVDSATLQLYDLVKDTSATCVAENNAGKTQEA-- 1213
Query: 1565 VGIQQKPVITISNEDI---KQKHKVGDEWLVTAVIEGIPPPEVIWY----KNGNKLENDK 1617
V IQ T NE + ++ EW + G +I Y ++G++
Sbjct: 1214 VSIQVTGPGTAPNEIVLLPMPNQEINVEWTSPDEVNGQITNYIIHYGEISEDGSEPATWD 1273
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD-KPSKPEGPVIMR 1676
+ I + + E K++++ + + G S +K P P+I
Sbjct: 1274 QVTIARDDVNHKLANLEPKKTYAIRVQAVSDRGPGVISAPQVIKTLPLAPQAITNPIIQV 1333
Query: 1677 EISRESVTIEWKPPLD--DGGLELTKYAIE---KHEPDNNR-W--IKVADVDRDVETYCI 1728
SVTIE+ PP D + G ++ + I+ EPD+ W +K D D +T +
Sbjct: 1334 H-PNNSVTIEFTPPDDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFTDPDDTDDTTIV 1392
Query: 1729 ----QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
+ N + +Y R+IA+ + ++ +EP + T
Sbjct: 1393 SIDGENFNPDTKYNTRIIARGEI---DSQPNEPTLFAT 1427
Score = 58.8 bits (136), Expect = 4e-08
Identities = 51/196 (26%), Positives = 85/196 (43%), Gaps = 16/196 (8%)
Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE----YNITTKEK 1626
PV+ + + K DE ++ +G+P P++IW +G +E+ KE Y+ T +
Sbjct: 619 PVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTDA 678
Query: 1627 TSVIRIKELKRS--HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
R K + +S S T +A N+ G+ +V +K+ S P G I
Sbjct: 679 QDRTRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKILGPGSAPLG--ITPTPMHTGFD 736
Query: 1685 IEWKPPLDDGGLELTKYAI-EKHEPDN--NRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
+ WKPP G +T Y + +PD + W + V D + +E+ Y+ +V
Sbjct: 737 VAWKPPKVTNG-RITDYVVYYSKDPDAPLSDW-ESKTVPADTRNLTVNVDDEDTPYVVKV 794
Query: 1742 IAQNPVG---FSEALE 1754
A+ G SEA E
Sbjct: 795 QARTDDGPGIISEAYE 810
Score = 53.2 bits (122), Expect = 2e-06
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P P ++W G L KT I++K S++++ A N AG S+ ++
Sbjct: 461 PVPVLVWLHKGRPLNKGS--------KTQHIKMKNGGVLESTQFSCVAENEAGKSTKKIN 512
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD--NNRWIKVA 1717
+ V PS PE I +I + VT++W+PP G +P ++W KV
Sbjct: 513 VTVTG-PSAPER--IRYQIDGDKVTLQWEPPQITNGPMAGYDVFYTEDPSLPRDQW-KVH 568
Query: 1718 DVDR-DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
+D + T + +LNE Y F ++ +N +G L S P T L
Sbjct: 569 HIDDPNARTTTVLRLNEKTPYTFVIVGRNRLG--PGLPSAPFTATTWL 614
Score = 52.0 bits (119), Expect = 5e-06
Identities = 69/298 (23%), Positives = 119/298 (39%), Gaps = 30/298 (10%)
Query: 633 PPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP +P+ Y V G +I + C VA P PDI W FK +++ D + +
Sbjct: 241 PPRIYIEPQGPYEVAPGGNINISCTSVAYPFPDIYW-FKNQKVNTDGPDQNTLRAS---- 295
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
+L I + + +E +T V+ N G A+ + + + TG P LKS +
Sbjct: 296 -QILIIKEIYRNEE--FTCVSDNIHGSANRTVSI-VVTGPGSAPH----LKSASAGRTSL 347
Query: 752 VIL--SAQVVGNPRPTITWCKNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVY-TLK 806
+ ++ P T T N P + + K + + + P D Y ++
Sbjct: 348 TVRWEPPSIINRPITTYTLYYTNNPQQPVKNWKKLEVKEPTREVAIPDLRPDTAYYIRVR 407
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NPVPSIT 865
A + G + + + + + P + I EI V ++ VTR +PVP +
Sbjct: 408 ANDPLGPGKLGNQVQI-KTLKPAVRPYVNIVEGDEIRVPPMTAFEIDCNVTRADPVPVLV 466
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W ++ TQ+ +N ++S + CVA N AGKS+ VT+
Sbjct: 467 WLHKGRPLNKGSK-TQHIKMKN--------GGVLESTQFSCVAENEAGKSTKKINVTV 515
Score = 51.6 bits (118), Expect = 6e-06
Identities = 46/198 (23%), Positives = 86/198 (43%), Gaps = 15/198 (7%)
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
SK+ + +K ++ + EN G + ++NVT+ PS P + +ID + +
Sbjct: 478 SKTQHIKMKNGGVLESTQFSCVAENEAGKSTKKINVTVTG-PSAPERIRY-QIDGDKVTL 535
Query: 1400 CWDEPENTGNSTIIYYVVEYQE---IDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAY 1454
W+ P+ T N + Y V Y E + +W + + T++ L + Y F
Sbjct: 536 QWEPPQIT-NGPMAGYDVFYTEDPSLPRDQWKVHHIDDPNARTTTVLRLNEKTPYTFVIV 594
Query: 1455 AVNEVD--ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELTCIFGGVPQP 1511
N + + A T + K +Q +P + +T EP N+++ + C GVP+P
Sbjct: 595 GRNRLGPGLPSAPFTATTWLAAKPPVVQL----EPSEEMTKEPSNDEMIIECGAQGVPKP 650
Query: 1512 KVTWYRDGKKLKTAKATY 1529
K+ W G ++ K +
Sbjct: 651 KIIWLWSGTLIEDGKEEF 668
Score = 51.6 bits (118), Expect = 6e-06
Identities = 94/420 (22%), Positives = 157/420 (37%), Gaps = 57/420 (13%)
Query: 1682 SVTIEWKPPLDDGG--LELTKY-AIEKHEPDNNRWIKVA-----DVDRDVETYCIQKLNE 1733
+V I W PP G T Y A E + D W +++ D T ++ N
Sbjct: 1047 TVNITWSPPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFNP 1106
Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTAL-DVPSXXXXXXXXXXIDNESVYITWFPSE 1792
N Y R+ A N + SE S+P+ +T ++P + S Y E
Sbjct: 1107 NTPYKIRISATNDL--SEGPASDPVRFETGSGEIPPTITLD------PSNSTYTV----E 1154
Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
G + I + Q W A +Q + A N G +
Sbjct: 1155 PLGAATITCTATGVPQPKVHWIKANGETVDSATLQLYDLVKDTSATCVAENNAGKT---- 1210
Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV----- 1907
+ ++I T P + P V+ ++ + ++WT P+ G ITNYII + +
Sbjct: 1211 -QEAVSIQVT-GPGTAPNEIVLLPMPNQEINVEWTSPDEVNGQ-ITNYIIHYGEISEDGS 1267
Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
+ +W + VT+ H + N++ K R+ A + G + + Q ++ T+P
Sbjct: 1268 EPATWDQ-VTIARDDVNHKLANLEPKKTYAIRVQAVSDRGPGVISAPQVIK-----TLPL 1321
Query: 1968 PPTAPLE-IRMVGSNIVMTSWGTPEWDGGAP-------LLGYNIAIRDVTKTMWMEV--- 2016
P A I V N +T TP D P ++ Y +++W E+
Sbjct: 1322 APQAITNPIIQVHPNNSVTIEFTPPDDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFT 1381
Query: 2017 ---GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
D + + + + + Y RI AR EI S+P +EP G+G A +P
Sbjct: 1382 DPDDTDDTTIVSIDGENFNPDTKYNTRIIARGEID-SQP---NEPTLFATGDGVIAPSQP 1437
Score = 48.4 bits (110), Expect = 6e-05
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P P++ W+KN + + N T + ++ IKE+ R+ ++T + N G+++ V+
Sbjct: 270 PFPDIYWFKNQKVNTDGPDQN--TLRASQILIIKEIYRNE--EFTCVSDNIHGSANRTVS 325
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPP--LDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+ V S P + R S+T+ W+PP ++ T Y + W K+
Sbjct: 326 IVVTGPGSAPH--LKSASAGRTSLTVRWEPPSIINRPITTYTLYYTNNPQQPVKNWKKL- 382
Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
+V I L + Y RV A +P+G
Sbjct: 383 EVKEPTREVAIPDLRPDTAYYIRVRANDPLG 413
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
I++E P G + C YP P I WF+ + D L+I
Sbjct: 244 IYIEPQGPYEVAPGGNINISCTSVAYPFPDIYWFKNQKVNTDGPDQNTLRASQ---ILII 300
Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+E++ + FTCV+ N G A+ T ++V P
Sbjct: 301 KEIYRNE--EFTCVSDNIHGSANRTVSIVVTGP 331
Score = 46.0 bits (104), Expect = 3e-04
Identities = 49/222 (22%), Positives = 86/222 (38%), Gaps = 22/222 (9%)
Query: 1285 EFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E PP I Y ++ T+ PQP WI K ++DS +
Sbjct: 1137 EIPPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWI---------KANGETVDSAT 1187
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
L V++T A ENN G +++ + + P + +L + + IN+ W
Sbjct: 1188 LQL-YDLVKDTSATCVA---ENNAGKTQEAVSIQVTGPGTAPNEIVLLPMPNQEINVEWT 1243
Query: 1403 EPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
P+ N I Y++ Y EI D +E + +T + + + N + + YA+
Sbjct: 1244 SPDEV-NGQITNYIIHYGEISEDGSEPATWDQVTIARDDVNHKLANLEPK-KTYAIRVQA 1301
Query: 1461 ISDASE-TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
+SD +VIK + + P+ I PN + +
Sbjct: 1302 VSDRGPGVISAPQVIKTLPLAPQAITNPI--IQVHPNNSVTI 1341
Score = 44.0 bits (99), Expect = 0.001
Identities = 66/333 (19%), Positives = 129/333 (38%), Gaps = 31/333 (9%)
Query: 1238 DTEKFTLISDVKK---RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI-VDY 1293
D ++ T I + K R+L C + ++ C D K K ++ PP+I ++
Sbjct: 193 DVDEKTCIKPIPKSLCRSLSGCTCNGITETQFACSCGDNKQ----KCLLIAGPPRIYIEP 248
Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS--LTIKKVE 1351
+ Y + G ++ + A+P P+ W N K+ P ++ AS L IK++
Sbjct: 249 QGPYEVAPGGNINISCTSVAYPFPDIYWFKNQKV----NTDGPDQNTLRASQILIIKEIY 304
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+ + +N G A+ +++ + S P + +S+ + W EP + N
Sbjct: 305 RNEE--FTCVSDNIHGSANRTVSIVVTGPGSAPHLKS-ASAGRTSLTVRW-EPPSIINRP 360
Query: 1412 IIYYVVEY-----QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
I Y + Y Q + + + VK T+ + +I +L+ +++Y R A + +
Sbjct: 361 ITTYTLYYTNNPQQPVKNWKKLEVKEPTR-EVAIPDLRPDTAYYIRVRANDPLGPGKLGN 419
Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTA 1525
+ + + VE I P E+ C + P P + W G+ L
Sbjct: 420 QVQIKTLKPAVRPYVNIVEG--DEIRVPPMTAFEIDCNVTRADPVPVLVWLHKGRPLNKG 477
Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
T + + C+A N+ G+
Sbjct: 478 SKTQHIK----MKNGGVLESTQFSCVAENEAGK 506
Score = 44.0 bits (99), Expect = 0.001
Identities = 84/388 (21%), Positives = 147/388 (37%), Gaps = 35/388 (9%)
Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP-EFILVPANTD 1213
K Q +K+ + + ++ ++SC E G S +TV PS +R + V +
Sbjct: 479 KTQHIKMKNGGVLESTQFSCVAENEAGKSTKKINVTVTGPSAPERIRYQIDGDKVTLQWE 538
Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
P DV + + S+ D K I D RT + + E + YT V++
Sbjct: 539 PPQITNGPMAGYDVFYTEDPSLPRDQWKVHHIDDPNARTTTVLRLNE--KTPYTFVIVGR 596
Query: 1274 K-------STTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDY--QAFPQPNDEWIV 1323
S + P +V E E K S+ ++++ Q P+P W+
Sbjct: 597 NRLGPGLPSAPFTATTWLAAKPPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLW 656
Query: 1324 NSKIIKKCKH------TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ +I+ K T P+ + T +G+ + N+ G + ++ V I
Sbjct: 657 SGTLIEDGKEEFRVYDTTPTDAQDRTRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKI 716
Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWISVKNIT 1434
L S P + + ++ W P+ T N I YVV Y + ++W S
Sbjct: 717 LGPGSAPLGITPTPMHTG-FDVAWKPPKVT-NGRITDYVVYYSKDPDAPLSDWESKTVPA 774
Query: 1435 KTQTSIQNLKTNSS-YRFRAYAVNEVD---ISDASETTEYYKVIK---ETKIQSPTVEKP 1487
T+ N+ + Y + A + IS+A E T K + +I P+V+
Sbjct: 775 DTRNLTVNVDDEDTPYVVKVQARTDDGPGIISEAYEVTTGRKQVPLSVRLEIADPSVDPS 834
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTW 1515
EP + I C+ G P P V++
Sbjct: 835 TGETIVEPTQPIHFRCVADGRPMPSVSY 862
Score = 41.5 bits (93), Expect = 0.006
Identities = 86/388 (22%), Positives = 152/388 (39%), Gaps = 36/388 (9%)
Query: 1401 WDEPENTGNSTI---IYYV---VEYQEIDTT---EWI--SVKNITKTQTSIQNLKT-NSS 1448
W EP + I IYYV +E D+ +WI S+ + TK IQNL ++
Sbjct: 1657 WKEPVTSDVPPIGYEIYYVRGDKSVEEDDSAGLNDWIKISIDDPTKLTHKIQNLLLPDTD 1716
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETK---IQSPTVEKPLKNITTE---PNEDIELT 1502
Y F+ A+ S SE K + + IQ T + ++ TT P + +
Sbjct: 1717 YVFKMRAIYPDGPSVFSEPC-IMKTLPDGNAPYIQISTGDNGVEGSTTIQILPGSQMTIA 1775
Query: 1503 CIFGGVPQPKVTWYRDGK-KLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G+P P+V W + G ++ ++ + N + C+A N G
Sbjct: 1776 CNATGIPLPQVKWIKAGNYEIDPSRVDADGNHAQFSLQVANITEDTTFNCVAQNPLGHAN 1835
Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPE--VIWYKNGNKLEND 1616
+ V + + ++ + K G LV + E + PP I Y + + D
Sbjct: 1836 WTINVNLIEGLEPNWRDDFVTSKSDGGQIVLVFNDELPEYLKPPNEWTIQYTDDAEQPKD 1895
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
+ +I + + R++ + + Y + N ++ V P KP +
Sbjct: 1896 QWESIPS-GGAPLTRVEVPNMNPGTFYYLVVDNP--EKGIQTPTLVVMTP-KPPSDIRFG 1951
Query: 1677 EISRESVTIEWKPPLDDGGL-ELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNEN 1734
+ + + +++KP + + E T +P N ++ ADV V + L +
Sbjct: 1952 KNNDDEQIVDFKPAVASEPIKEYTISVWPSTDPSNVKKFTTPADVTSGV---VVDGLEPD 2008
Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKT 1762
EY +V A+ G E L SEP+ +KT
Sbjct: 2009 TEYNVQVAAEFYEG--EELASEPVTVKT 2034
Score = 35.1 bits (77), Expect = 0.55
Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 16/135 (11%)
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY-KNGNKLENDKEYNITTKEKTS 1628
+P + ED + G ++ + V EG P P+V W +GN+L +
Sbjct: 1436 QPSFNVDTEDGVIRVPAGTDYTIKCVSEGYPAPDVRWVDSHGNQLSDG-----------P 1484
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
++RI +++++ ++K A N G ++T+ V + PE + + +++++++
Sbjct: 1485 LLRIIDIRKTLNAKCL--AENRGGLKETDLTIFVAGPGTAPEN-IQLTANKPTTISVQYE 1541
Query: 1689 PPLDDGGLELTKYAI 1703
P G ++KY I
Sbjct: 1542 VPSIPNG-NISKYII 1555
Score = 34.3 bits (75), Expect = 0.97
Identities = 38/132 (28%), Positives = 54/132 (40%), Gaps = 14/132 (10%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKS-MIVRQGESVILSAQVVGNPRPTITWCKNNKP 774
EG AS P+ + +GE P ++P S V + ++ G P+P + W K N
Sbjct: 1122 EGPASDPVRFETGSGEIPPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWIKAN-- 1179
Query: 775 VKALPTKSDGDT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
G+T S T+ VKD T AEN+ G + + I V P E
Sbjct: 1180 ---------GETVDSATLQLYDLVKDTSA-TCVAENNAGKTQEAVSIQVTGPGTAPNEIV 1229
Query: 834 LFINRFQEITVK 845
L QEI V+
Sbjct: 1230 LLPMPNQEINVE 1241
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 633 PPTFSKKPKAQYVDEGS--DILLECRLVAIPEPDIAWLFKG---EEIVPDENISVAIESD 687
PP +P + E S ++++EC +P+P I WL+ G E+ + + +D
Sbjct: 618 PPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTD 677
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
+ K+ + G T AVN EG + +KI G P I P
Sbjct: 678 AQDR-TRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKI-LGPGSAPLGITP 728
Score = 33.9 bits (74), Expect = 1.3
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
GS + C G P PQ+ W + I PS+ D N A ++ + TF
Sbjct: 1769 GSQMTIACNATGIPLPQVKWIKAGNYEIDPSR----VDADGNHAQFSLQVANITEDTTFN 1824
Query: 583 CVAKNAAGFASST 595
CVA+N G A+ T
Sbjct: 1825 CVAQNPLGHANWT 1837
Score = 31.9 bits (69), Expect = 5.2
Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 14/127 (11%)
Query: 1402 DEPENTGNST---IIYYVVEYQEIDTTEWISVKNITKTQT------SI--QNLKTNSSYR 1450
D+PEN G +I Y + + D + W +K T SI +N ++ Y
Sbjct: 1347 DDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFTDPDDTDDTTIVSIDGENFNPDTKYN 1406
Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGV 1508
R A E+D S +E T + P+ ++ I D + C+ G
Sbjct: 1407 TRIIARGEID-SQPNEPTLFATGDGVIAPSQPSFNVDTEDGVIRVPAGTDYTIKCVSEGY 1465
Query: 1509 PQPKVTW 1515
P P V W
Sbjct: 1466 PAPDVRW 1472
Score = 31.1 bits (67), Expect = 9.0
Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD------DDNVATLVIREVFP 575
P + EC +G P+P+I W +I+ ++ YD D + +I +
Sbjct: 633 PSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTDAQDRTRSKLIAQSTT 692
Query: 576 EDAGTFTCVAKNAAG 590
+G TC A N+ G
Sbjct: 693 R-SGVATCQAVNSEG 706
Score = 31.1 bits (67), Expect = 9.0
Identities = 32/159 (20%), Positives = 64/159 (40%), Gaps = 9/159 (5%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
+I GS +T+ + P P +WI + ++ D A +++ T+
Sbjct: 1765 QILPGSQMTIACNATGIPLPQVKWIKAGNY--EIDPSRVDADGNHAQFSLQVANITEDTT 1822
Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICWDE--PE--NTGNST 1411
+ +N GHA+ +NV +++ P + + + + D I + +++ PE N
Sbjct: 1823 FNCVAQNPLGHANWTINVNLIEGLEPNWRDDFVTSKSDGGQIVLVFNDELPEYLKPPNEW 1882
Query: 1412 IIYYVVE-YQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
I Y + Q D E I T+ + N+ + Y
Sbjct: 1883 TIQYTDDAEQPKDQWESIPSGGAPLTRVEVPNMNPGTFY 1921
>U00054-2|AAA50715.2| 13100|Caenorhabditis elegans Hypothetical
protein K07E12.1a protein.
Length = 13100
Score = 63.3 bits (147), Expect = 2e-09
Identities = 90/398 (22%), Positives = 155/398 (38%), Gaps = 46/398 (11%)
Query: 1395 SSINICWDEP-ENTG--NSTIIYYVVEYQEIDTTEW--ISVK-----NITKTQTSIQNLK 1444
+++NI W P + G S +Y+ EY + D W ISV + + +
Sbjct: 1109 NTVNITWSPPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFN 1168
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
N+ Y+ R A N++ AS+ + E + T++ T EP +TC
Sbjct: 1169 PNTPYKIRISATNDLSEGPASDPVRFETGSGEIP-PTITLDPSNSTYTVEPLGAATITCT 1227
Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
GVPQPKV W KA E C+A N+ G+ + +
Sbjct: 1228 ATGVPQPKVHW---------IKANGETVDSATLQLYDLVKDTSATCVAENNAGKTQEA-- 1276
Query: 1565 VGIQQKPVITISNEDI---KQKHKVGDEWLVTAVIEGIPPPEVIWY----KNGNKLENDK 1617
V IQ T NE + ++ EW + G +I Y ++G++
Sbjct: 1277 VSIQVTGPGTAPNEIVLLPMPNQEINVEWTSPDEVNGQITNYIIHYGEISEDGSEPATWD 1336
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD-KPSKPEGPVIMR 1676
+ I + + E K++++ + + G S +K P P+I
Sbjct: 1337 QVTIARDDVNHKLANLEPKKTYAIRVQAVSDRGPGVISAPQVIKTLPLAPQAITNPIIQV 1396
Query: 1677 EISRESVTIEWKPPLD--DGGLELTKYAIE---KHEPDNNR-W--IKVADVDRDVETYCI 1728
SVTIE+ PP D + G ++ + I+ EPD+ W +K D D +T +
Sbjct: 1397 H-PNNSVTIEFTPPDDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFTDPDDTDDTTIV 1455
Query: 1729 ----QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
+ N + +Y R+IA+ + ++ +EP + T
Sbjct: 1456 SIDGENFNPDTKYNTRIIARGEI---DSQPNEPTLFAT 1490
Score = 58.8 bits (136), Expect = 4e-08
Identities = 51/196 (26%), Positives = 85/196 (43%), Gaps = 16/196 (8%)
Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE----YNITTKEK 1626
PV+ + + K DE ++ +G+P P++IW +G +E+ KE Y+ T +
Sbjct: 682 PVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTDA 741
Query: 1627 TSVIRIKELKRS--HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
R K + +S S T +A N+ G+ +V +K+ S P G I
Sbjct: 742 QDRTRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKILGPGSAPLG--ITPTPMHTGFD 799
Query: 1685 IEWKPPLDDGGLELTKYAI-EKHEPDN--NRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
+ WKPP G +T Y + +PD + W + V D + +E+ Y+ +V
Sbjct: 800 VAWKPPKVTNG-RITDYVVYYSKDPDAPLSDW-ESKTVPADTRNLTVNVDDEDTPYVVKV 857
Query: 1742 IAQNPVG---FSEALE 1754
A+ G SEA E
Sbjct: 858 QARTDDGPGIISEAYE 873
Score = 53.2 bits (122), Expect = 2e-06
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P P ++W G L KT I++K S++++ A N AG S+ ++
Sbjct: 524 PVPVLVWLHKGRPLNKGS--------KTQHIKMKNGGVLESTQFSCVAENEAGKSTKKIN 575
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD--NNRWIKVA 1717
+ V PS PE I +I + VT++W+PP G +P ++W KV
Sbjct: 576 VTVTG-PSAPER--IRYQIDGDKVTLQWEPPQITNGPMAGYDVFYTEDPSLPRDQW-KVH 631
Query: 1718 DVDR-DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
+D + T + +LNE Y F ++ +N +G L S P T L
Sbjct: 632 HIDDPNARTTTVLRLNEKTPYTFVIVGRNRLG--PGLPSAPFTATTWL 677
Score = 52.0 bits (119), Expect = 5e-06
Identities = 69/298 (23%), Positives = 119/298 (39%), Gaps = 30/298 (10%)
Query: 633 PPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP +P+ Y V G +I + C VA P PDI W FK +++ D + +
Sbjct: 304 PPRIYIEPQGPYEVAPGGNINISCTSVAYPFPDIYW-FKNQKVNTDGPDQNTLRAS---- 358
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
+L I + + +E +T V+ N G A+ + + + TG P LKS +
Sbjct: 359 -QILIIKEIYRNEE--FTCVSDNIHGSANRTVSI-VVTGPGSAPH----LKSASAGRTSL 410
Query: 752 VIL--SAQVVGNPRPTITWCKNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVY-TLK 806
+ ++ P T T N P + + K + + + P D Y ++
Sbjct: 411 TVRWEPPSIINRPITTYTLYYTNNPQQPVKNWKKLEVKEPTREVAIPDLRPDTAYYIRVR 470
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NPVPSIT 865
A + G + + + + + P + I EI V ++ VTR +PVP +
Sbjct: 471 ANDPLGPGKLGNQVQI-KTLKPAVRPYVNIVEGDEIRVPPMTAFEIDCNVTRADPVPVLV 529
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W ++ TQ+ +N ++S + CVA N AGKS+ VT+
Sbjct: 530 WLHKGRPLNKGSK-TQHIKMKN--------GGVLESTQFSCVAENEAGKSTKKINVTV 578
Score = 51.6 bits (118), Expect = 6e-06
Identities = 46/198 (23%), Positives = 86/198 (43%), Gaps = 15/198 (7%)
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
SK+ + +K ++ + EN G + ++NVT+ PS P + +ID + +
Sbjct: 541 SKTQHIKMKNGGVLESTQFSCVAENEAGKSTKKINVTVTG-PSAPERIRY-QIDGDKVTL 598
Query: 1400 CWDEPENTGNSTIIYYVVEYQE---IDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAY 1454
W+ P+ T N + Y V Y E + +W + + T++ L + Y F
Sbjct: 599 QWEPPQIT-NGPMAGYDVFYTEDPSLPRDQWKVHHIDDPNARTTTVLRLNEKTPYTFVIV 657
Query: 1455 AVNEVD--ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELTCIFGGVPQP 1511
N + + A T + K +Q +P + +T EP N+++ + C GVP+P
Sbjct: 658 GRNRLGPGLPSAPFTATTWLAAKPPVVQL----EPSEEMTKEPSNDEMIIECGAQGVPKP 713
Query: 1512 KVTWYRDGKKLKTAKATY 1529
K+ W G ++ K +
Sbjct: 714 KIIWLWSGTLIEDGKEEF 731
Score = 51.6 bits (118), Expect = 6e-06
Identities = 94/420 (22%), Positives = 157/420 (37%), Gaps = 57/420 (13%)
Query: 1682 SVTIEWKPPLDDGG--LELTKY-AIEKHEPDNNRWIKVA-----DVDRDVETYCIQKLNE 1733
+V I W PP G T Y A E + D W +++ D T ++ N
Sbjct: 1110 TVNITWSPPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFNP 1169
Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTAL-DVPSXXXXXXXXXXIDNESVYITWFPSE 1792
N Y R+ A N + SE S+P+ +T ++P + S Y E
Sbjct: 1170 NTPYKIRISATNDL--SEGPASDPVRFETGSGEIPPTITLD------PSNSTYTV----E 1217
Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
G + I + Q W A +Q + A N G +
Sbjct: 1218 PLGAATITCTATGVPQPKVHWIKANGETVDSATLQLYDLVKDTSATCVAENNAGKT---- 1273
Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV----- 1907
+ ++I T P + P V+ ++ + ++WT P+ G ITNYII + +
Sbjct: 1274 -QEAVSIQVT-GPGTAPNEIVLLPMPNQEINVEWTSPDEVNGQ-ITNYIIHYGEISEDGS 1330
Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
+ +W + VT+ H + N++ K R+ A + G + + Q ++ T+P
Sbjct: 1331 EPATWDQ-VTIARDDVNHKLANLEPKKTYAIRVQAVSDRGPGVISAPQVIK-----TLPL 1384
Query: 1968 PPTAPLE-IRMVGSNIVMTSWGTPEWDGGAP-------LLGYNIAIRDVTKTMWMEV--- 2016
P A I V N +T TP D P ++ Y +++W E+
Sbjct: 1385 APQAITNPIIQVHPNNSVTIEFTPPDDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFT 1444
Query: 2017 ---GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
D + + + + + Y RI AR EI S+P +EP G+G A +P
Sbjct: 1445 DPDDTDDTTIVSIDGENFNPDTKYNTRIIARGEID-SQP---NEPTLFATGDGVIAPSQP 1500
Score = 48.4 bits (110), Expect = 6e-05
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P P++ W+KN + + N T + ++ IKE+ R+ ++T + N G+++ V+
Sbjct: 333 PFPDIYWFKNQKVNTDGPDQN--TLRASQILIIKEIYRNE--EFTCVSDNIHGSANRTVS 388
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPP--LDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+ V S P + R S+T+ W+PP ++ T Y + W K+
Sbjct: 389 IVVTGPGSAPH--LKSASAGRTSLTVRWEPPSIINRPITTYTLYYTNNPQQPVKNWKKL- 445
Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
+V I L + Y RV A +P+G
Sbjct: 446 EVKEPTREVAIPDLRPDTAYYIRVRANDPLG 476
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
I++E P G + C YP P I WF+ + D L+I
Sbjct: 307 IYIEPQGPYEVAPGGNINISCTSVAYPFPDIYWFKNQKVNTDGPDQNTLRASQ---ILII 363
Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+E++ + FTCV+ N G A+ T ++V P
Sbjct: 364 KEIYRNE--EFTCVSDNIHGSANRTVSIVVTGP 394
Score = 46.0 bits (104), Expect = 3e-04
Identities = 49/222 (22%), Positives = 86/222 (38%), Gaps = 22/222 (9%)
Query: 1285 EFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E PP I Y ++ T+ PQP WI K ++DS +
Sbjct: 1200 EIPPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWI---------KANGETVDSAT 1250
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
L V++T A ENN G +++ + + P + +L + + IN+ W
Sbjct: 1251 LQL-YDLVKDTSATCVA---ENNAGKTQEAVSIQVTGPGTAPNEIVLLPMPNQEINVEWT 1306
Query: 1403 EPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
P+ N I Y++ Y EI D +E + +T + + + N + + YA+
Sbjct: 1307 SPDEV-NGQITNYIIHYGEISEDGSEPATWDQVTIARDDVNHKLANLEPK-KTYAIRVQA 1364
Query: 1461 ISDASE-TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
+SD +VIK + + P+ I PN + +
Sbjct: 1365 VSDRGPGVISAPQVIKTLPLAPQAITNPI--IQVHPNNSVTI 1404
Score = 44.0 bits (99), Expect = 0.001
Identities = 66/333 (19%), Positives = 129/333 (38%), Gaps = 31/333 (9%)
Query: 1238 DTEKFTLISDVKK---RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI-VDY 1293
D ++ T I + K R+L C + ++ C D K K ++ PP+I ++
Sbjct: 256 DVDEKTCIKPIPKSLCRSLSGCTCNGITETQFACSCGDNKQ----KCLLIAGPPRIYIEP 311
Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS--LTIKKVE 1351
+ Y + G ++ + A+P P+ W N K+ P ++ AS L IK++
Sbjct: 312 QGPYEVAPGGNINISCTSVAYPFPDIYWFKNQKV----NTDGPDQNTLRASQILIIKEIY 367
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+ + +N G A+ +++ + S P + +S+ + W EP + N
Sbjct: 368 RNEE--FTCVSDNIHGSANRTVSIVVTGPGSAPHLKS-ASAGRTSLTVRW-EPPSIINRP 423
Query: 1412 IIYYVVEY-----QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
I Y + Y Q + + + VK T+ + +I +L+ +++Y R A + +
Sbjct: 424 ITTYTLYYTNNPQQPVKNWKKLEVKEPTR-EVAIPDLRPDTAYYIRVRANDPLGPGKLGN 482
Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTA 1525
+ + + VE I P E+ C + P P + W G+ L
Sbjct: 483 QVQIKTLKPAVRPYVNIVEG--DEIRVPPMTAFEIDCNVTRADPVPVLVWLHKGRPLNKG 540
Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
T + + C+A N+ G+
Sbjct: 541 SKTQHIK----MKNGGVLESTQFSCVAENEAGK 569
Score = 44.0 bits (99), Expect = 0.001
Identities = 84/388 (21%), Positives = 147/388 (37%), Gaps = 35/388 (9%)
Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP-EFILVPANTD 1213
K Q +K+ + + ++ ++SC E G S +TV PS +R + V +
Sbjct: 542 KTQHIKMKNGGVLESTQFSCVAENEAGKSTKKINVTVTGPSAPERIRYQIDGDKVTLQWE 601
Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
P DV + + S+ D K I D RT + + E + YT V++
Sbjct: 602 PPQITNGPMAGYDVFYTEDPSLPRDQWKVHHIDDPNARTTTVLRLNE--KTPYTFVIVGR 659
Query: 1274 K-------STTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDY--QAFPQPNDEWIV 1323
S + P +V E E K S+ ++++ Q P+P W+
Sbjct: 660 NRLGPGLPSAPFTATTWLAAKPPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLW 719
Query: 1324 NSKIIKKCKH------TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ +I+ K T P+ + T +G+ + N+ G + ++ V I
Sbjct: 720 SGTLIEDGKEEFRVYDTTPTDAQDRTRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKI 779
Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWISVKNIT 1434
L S P + + ++ W P+ T N I YVV Y + ++W S
Sbjct: 780 LGPGSAPLGITPTPMHTG-FDVAWKPPKVT-NGRITDYVVYYSKDPDAPLSDWESKTVPA 837
Query: 1435 KTQTSIQNLKTNSS-YRFRAYAVNEVD---ISDASETTEYYKVIK---ETKIQSPTVEKP 1487
T+ N+ + Y + A + IS+A E T K + +I P+V+
Sbjct: 838 DTRNLTVNVDDEDTPYVVKVQARTDDGPGIISEAYEVTTGRKQVPLSVRLEIADPSVDPS 897
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTW 1515
EP + I C+ G P P V++
Sbjct: 898 TGETIVEPTQPIHFRCVADGRPMPSVSY 925
Score = 41.5 bits (93), Expect = 0.006
Identities = 86/388 (22%), Positives = 152/388 (39%), Gaps = 36/388 (9%)
Query: 1401 WDEPENTGNSTI---IYYV---VEYQEIDTT---EWI--SVKNITKTQTSIQNLKT-NSS 1448
W EP + I IYYV +E D+ +WI S+ + TK IQNL ++
Sbjct: 1720 WKEPVTSDVPPIGYEIYYVRGDKSVEEDDSAGLNDWIKISIDDPTKLTHKIQNLLLPDTD 1779
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETK---IQSPTVEKPLKNITTE---PNEDIELT 1502
Y F+ A+ S SE K + + IQ T + ++ TT P + +
Sbjct: 1780 YVFKMRAIYPDGPSVFSEPC-IMKTLPDGNAPYIQISTGDNGVEGSTTIQILPGSQMTIA 1838
Query: 1503 CIFGGVPQPKVTWYRDGK-KLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G+P P+V W + G ++ ++ + N + C+A N G
Sbjct: 1839 CNATGIPLPQVKWIKAGNYEIDPSRVDADGNHAQFSLQVANITEDTTFNCVAQNPLGHAN 1898
Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPE--VIWYKNGNKLEND 1616
+ V + + ++ + K G LV + E + PP I Y + + D
Sbjct: 1899 WTINVNLIEGLEPNWRDDFVTSKSDGGQIVLVFNDELPEYLKPPNEWTIQYTDDAEQPKD 1958
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
+ +I + + R++ + + Y + N ++ V P KP +
Sbjct: 1959 QWESIPS-GGAPLTRVEVPNMNPGTFYYLVVDNP--EKGIQTPTLVVMTP-KPPSDIRFG 2014
Query: 1677 EISRESVTIEWKPPLDDGGL-ELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNEN 1734
+ + + +++KP + + E T +P N ++ ADV V + L +
Sbjct: 2015 KNNDDEQIVDFKPAVASEPIKEYTISVWPSTDPSNVKKFTTPADVTSGV---VVDGLEPD 2071
Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKT 1762
EY +V A+ G E L SEP+ +KT
Sbjct: 2072 TEYNVQVAAEFYEG--EELASEPVTVKT 2097
Score = 35.1 bits (77), Expect = 0.55
Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 16/135 (11%)
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY-KNGNKLENDKEYNITTKEKTS 1628
+P + ED + G ++ + V EG P P+V W +GN+L +
Sbjct: 1499 QPSFNVDTEDGVIRVPAGTDYTIKCVSEGYPAPDVRWVDSHGNQLSDG-----------P 1547
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
++RI +++++ ++K A N G ++T+ V + PE + + +++++++
Sbjct: 1548 LLRIIDIRKTLNAKCL--AENRGGLKETDLTIFVAGPGTAPEN-IQLTANKPTTISVQYE 1604
Query: 1689 PPLDDGGLELTKYAI 1703
P G ++KY I
Sbjct: 1605 VPSIPNG-NISKYII 1618
Score = 34.3 bits (75), Expect = 0.97
Identities = 38/132 (28%), Positives = 54/132 (40%), Gaps = 14/132 (10%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKS-MIVRQGESVILSAQVVGNPRPTITWCKNNKP 774
EG AS P+ + +GE P ++P S V + ++ G P+P + W K N
Sbjct: 1185 EGPASDPVRFETGSGEIPPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWIKAN-- 1242
Query: 775 VKALPTKSDGDT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
G+T S T+ VKD T AEN+ G + + I V P E
Sbjct: 1243 ---------GETVDSATLQLYDLVKDTSA-TCVAENNAGKTQEAVSIQVTGPGTAPNEIV 1292
Query: 834 LFINRFQEITVK 845
L QEI V+
Sbjct: 1293 LLPMPNQEINVE 1304
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 633 PPTFSKKPKAQYVDEGS--DILLECRLVAIPEPDIAWLFKG---EEIVPDENISVAIESD 687
PP +P + E S ++++EC +P+P I WL+ G E+ + + +D
Sbjct: 681 PPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTD 740
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
+ K+ + G T AVN EG + +KI G P I P
Sbjct: 741 AQDR-TRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKI-LGPGSAPLGITP 791
Score = 33.9 bits (74), Expect = 1.3
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
GS + C G P PQ+ W + I PS+ D N A ++ + TF
Sbjct: 1832 GSQMTIACNATGIPLPQVKWIKAGNYEIDPSR----VDADGNHAQFSLQVANITEDTTFN 1887
Query: 583 CVAKNAAGFASST 595
CVA+N G A+ T
Sbjct: 1888 CVAQNPLGHANWT 1900
Score = 31.9 bits (69), Expect = 5.2
Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 14/127 (11%)
Query: 1402 DEPENTGNST---IIYYVVEYQEIDTTEWISVKNITKTQT------SI--QNLKTNSSYR 1450
D+PEN G +I Y + + D + W +K T SI +N ++ Y
Sbjct: 1410 DDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFTDPDDTDDTTIVSIDGENFNPDTKYN 1469
Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGV 1508
R A E+D S +E T + P+ ++ I D + C+ G
Sbjct: 1470 TRIIARGEID-SQPNEPTLFATGDGVIAPSQPSFNVDTEDGVIRVPAGTDYTIKCVSEGY 1528
Query: 1509 PQPKVTW 1515
P P V W
Sbjct: 1529 PAPDVRW 1535
Score = 31.1 bits (67), Expect = 9.0
Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD------DDNVATLVIREVFP 575
P + EC +G P+P+I W +I+ ++ YD D + +I +
Sbjct: 696 PSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTDAQDRTRSKLIAQSTT 755
Query: 576 EDAGTFTCVAKNAAG 590
+G TC A N+ G
Sbjct: 756 R-SGVATCQAVNSEG 769
Score = 31.1 bits (67), Expect = 9.0
Identities = 32/159 (20%), Positives = 64/159 (40%), Gaps = 9/159 (5%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
+I GS +T+ + P P +WI + ++ D A +++ T+
Sbjct: 1828 QILPGSQMTIACNATGIPLPQVKWIKAGNY--EIDPSRVDADGNHAQFSLQVANITEDTT 1885
Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICWDE--PE--NTGNST 1411
+ +N GHA+ +NV +++ P + + + + D I + +++ PE N
Sbjct: 1886 FNCVAQNPLGHANWTINVNLIEGLEPNWRDDFVTSKSDGGQIVLVFNDELPEYLKPPNEW 1945
Query: 1412 IIYYVVE-YQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
I Y + Q D E I T+ + N+ + Y
Sbjct: 1946 TIQYTDDAEQPKDQWESIPSGGAPLTRVEVPNMNPGTFY 1984
>AY117398-1|AAM78593.1| 13100|Caenorhabditis elegans mesocentin
protein.
Length = 13100
Score = 63.3 bits (147), Expect = 2e-09
Identities = 90/398 (22%), Positives = 155/398 (38%), Gaps = 46/398 (11%)
Query: 1395 SSINICWDEP-ENTG--NSTIIYYVVEYQEIDTTEW--ISVK-----NITKTQTSIQNLK 1444
+++NI W P + G S +Y+ EY + D W ISV + + +
Sbjct: 1109 NTVNITWSPPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFN 1168
Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
N+ Y+ R A N++ AS+ + E + T++ T EP +TC
Sbjct: 1169 PNTPYKIRISATNDLSEGPASDPVRFETGSGEIP-PTITLDPSNSTYTVEPLGAATITCT 1227
Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
GVPQPKV W KA E C+A N+ G+ + +
Sbjct: 1228 ATGVPQPKVHW---------IKANGETVDSATLQLYDLVKDTSATCVAENNAGKTQEA-- 1276
Query: 1565 VGIQQKPVITISNEDI---KQKHKVGDEWLVTAVIEGIPPPEVIWY----KNGNKLENDK 1617
V IQ T NE + ++ EW + G +I Y ++G++
Sbjct: 1277 VSIQVTGPGTAPNEIVLLPMPNQEINVEWTSPDEVNGQITNYIIHYGEISEDGSEPATWD 1336
Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD-KPSKPEGPVIMR 1676
+ I + + E K++++ + + G S +K P P+I
Sbjct: 1337 QVTIARDDVNHKLANLEPKKTYAIRVQAVSDRGPGVISAPQVIKTLPLAPQAITNPIIQV 1396
Query: 1677 EISRESVTIEWKPPLD--DGGLELTKYAIE---KHEPDNNR-W--IKVADVDRDVETYCI 1728
SVTIE+ PP D + G ++ + I+ EPD+ W +K D D +T +
Sbjct: 1397 H-PNNSVTIEFTPPDDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFTDPDDTDDTTIV 1455
Query: 1729 ----QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
+ N + +Y R+IA+ + ++ +EP + T
Sbjct: 1456 SIDGENFNPDTKYNTRIIARGEI---DSQPNEPTLFAT 1490
Score = 58.8 bits (136), Expect = 4e-08
Identities = 51/196 (26%), Positives = 85/196 (43%), Gaps = 16/196 (8%)
Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE----YNITTKEK 1626
PV+ + + K DE ++ +G+P P++IW +G +E+ KE Y+ T +
Sbjct: 682 PVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTDA 741
Query: 1627 TSVIRIKELKRS--HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
R K + +S S T +A N+ G+ +V +K+ S P G I
Sbjct: 742 QDRTRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKILGPGSAPLG--ITPTPMHTGFD 799
Query: 1685 IEWKPPLDDGGLELTKYAI-EKHEPDN--NRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
+ WKPP G +T Y + +PD + W + V D + +E+ Y+ +V
Sbjct: 800 VAWKPPKVTNG-RITDYVVYYSKDPDAPLSDW-ESKTVPADTRNLTVNVDDEDTPYVVKV 857
Query: 1742 IAQNPVG---FSEALE 1754
A+ G SEA E
Sbjct: 858 QARTDDGPGIISEAYE 873
Score = 53.2 bits (122), Expect = 2e-06
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P P ++W G L KT I++K S++++ A N AG S+ ++
Sbjct: 524 PVPVLVWLHKGRPLNKGS--------KTQHIKMKNGGVLESTQFSCVAENEAGKSTKKIN 575
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD--NNRWIKVA 1717
+ V PS PE I +I + VT++W+PP G +P ++W KV
Sbjct: 576 VTVTG-PSAPER--IRYQIDGDKVTLQWEPPQITNGPMAGYDVFYTEDPSLPRDQW-KVH 631
Query: 1718 DVDR-DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
+D + T + +LNE Y F ++ +N +G L S P T L
Sbjct: 632 HIDDPNARTTTVLRLNEKTPYTFVIVGRNRLG--PGLPSAPFTATTWL 677
Score = 52.0 bits (119), Expect = 5e-06
Identities = 69/298 (23%), Positives = 119/298 (39%), Gaps = 30/298 (10%)
Query: 633 PPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
PP +P+ Y V G +I + C VA P PDI W FK +++ D + +
Sbjct: 304 PPRIYIEPQGPYEVAPGGNINISCTSVAYPFPDIYW-FKNQKVNTDGPDQNTLRAS---- 358
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
+L I + + +E +T V+ N G A+ + + + TG P LKS +
Sbjct: 359 -QILIIKEIYRNEE--FTCVSDNIHGSANRTVSI-VVTGPGSAPH----LKSASAGRTSL 410
Query: 752 VIL--SAQVVGNPRPTITWCKNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVY-TLK 806
+ ++ P T T N P + + K + + + P D Y ++
Sbjct: 411 TVRWEPPSIINRPITTYTLYYTNNPQQPVKNWKKLEVKEPTREVAIPDLRPDTAYYIRVR 470
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NPVPSIT 865
A + G + + + + + P + I EI V ++ VTR +PVP +
Sbjct: 471 ANDPLGPGKLGNQVQI-KTLKPAVRPYVNIVEGDEIRVPPMTAFEIDCNVTRADPVPVLV 529
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
W ++ TQ+ +N ++S + CVA N AGKS+ VT+
Sbjct: 530 WLHKGRPLNKGSK-TQHIKMKN--------GGVLESTQFSCVAENEAGKSTKKINVTV 578
Score = 51.6 bits (118), Expect = 6e-06
Identities = 46/198 (23%), Positives = 86/198 (43%), Gaps = 15/198 (7%)
Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
SK+ + +K ++ + EN G + ++NVT+ PS P + +ID + +
Sbjct: 541 SKTQHIKMKNGGVLESTQFSCVAENEAGKSTKKINVTVTG-PSAPERIRY-QIDGDKVTL 598
Query: 1400 CWDEPENTGNSTIIYYVVEYQE---IDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAY 1454
W+ P+ T N + Y V Y E + +W + + T++ L + Y F
Sbjct: 599 QWEPPQIT-NGPMAGYDVFYTEDPSLPRDQWKVHHIDDPNARTTTVLRLNEKTPYTFVIV 657
Query: 1455 AVNEVD--ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELTCIFGGVPQP 1511
N + + A T + K +Q +P + +T EP N+++ + C GVP+P
Sbjct: 658 GRNRLGPGLPSAPFTATTWLAAKPPVVQL----EPSEEMTKEPSNDEMIIECGAQGVPKP 713
Query: 1512 KVTWYRDGKKLKTAKATY 1529
K+ W G ++ K +
Sbjct: 714 KIIWLWSGTLIEDGKEEF 731
Score = 51.6 bits (118), Expect = 6e-06
Identities = 94/420 (22%), Positives = 157/420 (37%), Gaps = 57/420 (13%)
Query: 1682 SVTIEWKPPLDDGG--LELTKY-AIEKHEPDNNRWIKVA-----DVDRDVETYCIQKLNE 1733
+V I W PP G T Y A E + D W +++ D T ++ N
Sbjct: 1110 TVNITWSPPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFNP 1169
Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTAL-DVPSXXXXXXXXXXIDNESVYITWFPSE 1792
N Y R+ A N + SE S+P+ +T ++P + S Y E
Sbjct: 1170 NTPYKIRISATNDL--SEGPASDPVRFETGSGEIPPTITLD------PSNSTYTV----E 1217
Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
G + I + Q W A +Q + A N G +
Sbjct: 1218 PLGAATITCTATGVPQPKVHWIKANGETVDSATLQLYDLVKDTSATCVAENNAGKT---- 1273
Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV----- 1907
+ ++I T P + P V+ ++ + ++WT P+ G ITNYII + +
Sbjct: 1274 -QEAVSIQVT-GPGTAPNEIVLLPMPNQEINVEWTSPDEVNGQ-ITNYIIHYGEISEDGS 1330
Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
+ +W + VT+ H + N++ K R+ A + G + + Q ++ T+P
Sbjct: 1331 EPATWDQ-VTIARDDVNHKLANLEPKKTYAIRVQAVSDRGPGVISAPQVIK-----TLPL 1384
Query: 1968 PPTAPLE-IRMVGSNIVMTSWGTPEWDGGAP-------LLGYNIAIRDVTKTMWMEV--- 2016
P A I V N +T TP D P ++ Y +++W E+
Sbjct: 1385 APQAITNPIIQVHPNNSVTIEFTPPDDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFT 1444
Query: 2017 ---GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
D + + + + + Y RI AR EI S+P +EP G+G A +P
Sbjct: 1445 DPDDTDDTTIVSIDGENFNPDTKYNTRIIARGEID-SQP---NEPTLFATGDGVIAPSQP 1500
Score = 48.4 bits (110), Expect = 6e-05
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
P P++ W+KN + + N T + ++ IKE+ R+ ++T + N G+++ V+
Sbjct: 333 PFPDIYWFKNQKVNTDGPDQN--TLRASQILIIKEIYRNE--EFTCVSDNIHGSANRTVS 388
Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPP--LDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+ V S P + R S+T+ W+PP ++ T Y + W K+
Sbjct: 389 IVVTGPGSAPH--LKSASAGRTSLTVRWEPPSIINRPITTYTLYYTNNPQQPVKNWKKL- 445
Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
+V I L + Y RV A +P+G
Sbjct: 446 EVKEPTREVAIPDLRPDTAYYIRVRANDPLG 476
Score = 46.8 bits (106), Expect = 2e-04
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
I++E P G + C YP P I WF+ + D L+I
Sbjct: 307 IYIEPQGPYEVAPGGNINISCTSVAYPFPDIYWFKNQKVNTDGPDQNTLRASQ---ILII 363
Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
+E++ + FTCV+ N G A+ T ++V P
Sbjct: 364 KEIYRNE--EFTCVSDNIHGSANRTVSIVVTGP 394
Score = 46.0 bits (104), Expect = 3e-04
Identities = 49/222 (22%), Positives = 86/222 (38%), Gaps = 22/222 (9%)
Query: 1285 EFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
E PP I Y ++ T+ PQP WI K ++DS +
Sbjct: 1200 EIPPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWI---------KANGETVDSAT 1250
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
L V++T A ENN G +++ + + P + +L + + IN+ W
Sbjct: 1251 LQL-YDLVKDTSATCVA---ENNAGKTQEAVSIQVTGPGTAPNEIVLLPMPNQEINVEWT 1306
Query: 1403 EPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
P+ N I Y++ Y EI D +E + +T + + + N + + YA+
Sbjct: 1307 SPDEV-NGQITNYIIHYGEISEDGSEPATWDQVTIARDDVNHKLANLEPK-KTYAIRVQA 1364
Query: 1461 ISDASE-TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
+SD +VIK + + P+ I PN + +
Sbjct: 1365 VSDRGPGVISAPQVIKTLPLAPQAITNPI--IQVHPNNSVTI 1404
Score = 44.0 bits (99), Expect = 0.001
Identities = 66/333 (19%), Positives = 129/333 (38%), Gaps = 31/333 (9%)
Query: 1238 DTEKFTLISDVKK---RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI-VDY 1293
D ++ T I + K R+L C + ++ C D K K ++ PP+I ++
Sbjct: 256 DVDEKTCIKPIPKSLCRSLSGCTCNGITETQFACSCGDNKQ----KCLLIAGPPRIYIEP 311
Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS--LTIKKVE 1351
+ Y + G ++ + A+P P+ W N K+ P ++ AS L IK++
Sbjct: 312 QGPYEVAPGGNINISCTSVAYPFPDIYWFKNQKV----NTDGPDQNTLRASQILIIKEIY 367
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
+ + +N G A+ +++ + S P + +S+ + W EP + N
Sbjct: 368 RNEE--FTCVSDNIHGSANRTVSIVVTGPGSAPHLKS-ASAGRTSLTVRW-EPPSIINRP 423
Query: 1412 IIYYVVEY-----QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
I Y + Y Q + + + VK T+ + +I +L+ +++Y R A + +
Sbjct: 424 ITTYTLYYTNNPQQPVKNWKKLEVKEPTR-EVAIPDLRPDTAYYIRVRANDPLGPGKLGN 482
Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTA 1525
+ + + VE I P E+ C + P P + W G+ L
Sbjct: 483 QVQIKTLKPAVRPYVNIVEG--DEIRVPPMTAFEIDCNVTRADPVPVLVWLHKGRPLNKG 540
Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
T + + C+A N+ G+
Sbjct: 541 SKTQHIK----MKNGGVLESTQFSCVAENEAGK 569
Score = 44.0 bits (99), Expect = 0.001
Identities = 84/388 (21%), Positives = 147/388 (37%), Gaps = 35/388 (9%)
Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP-EFILVPANTD 1213
K Q +K+ + + ++ ++SC E G S +TV PS +R + V +
Sbjct: 542 KTQHIKMKNGGVLESTQFSCVAENEAGKSTKKINVTVTGPSAPERIRYQIDGDKVTLQWE 601
Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
P DV + + S+ D K I D RT + + E + YT V++
Sbjct: 602 PPQITNGPMAGYDVFYTEDPSLPRDQWKVHHIDDPNARTTTVLRLNE--KTPYTFVIVGR 659
Query: 1274 K-------STTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDY--QAFPQPNDEWIV 1323
S + P +V E E K S+ ++++ Q P+P W+
Sbjct: 660 NRLGPGLPSAPFTATTWLAAKPPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLW 719
Query: 1324 NSKIIKKCKH------TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ +I+ K T P+ + T +G+ + N+ G + ++ V I
Sbjct: 720 SGTLIEDGKEEFRVYDTTPTDAQDRTRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKI 779
Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWISVKNIT 1434
L S P + + ++ W P+ T N I YVV Y + ++W S
Sbjct: 780 LGPGSAPLGITPTPMHTG-FDVAWKPPKVT-NGRITDYVVYYSKDPDAPLSDWESKTVPA 837
Query: 1435 KTQTSIQNLKTNSS-YRFRAYAVNEVD---ISDASETTEYYKVIK---ETKIQSPTVEKP 1487
T+ N+ + Y + A + IS+A E T K + +I P+V+
Sbjct: 838 DTRNLTVNVDDEDTPYVVKVQARTDDGPGIISEAYEVTTGRKQVPLSVRLEIADPSVDPS 897
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTW 1515
EP + I C+ G P P V++
Sbjct: 898 TGETIVEPTQPIHFRCVADGRPMPSVSY 925
Score = 41.5 bits (93), Expect = 0.006
Identities = 86/388 (22%), Positives = 152/388 (39%), Gaps = 36/388 (9%)
Query: 1401 WDEPENTGNSTI---IYYV---VEYQEIDTT---EWI--SVKNITKTQTSIQNLKT-NSS 1448
W EP + I IYYV +E D+ +WI S+ + TK IQNL ++
Sbjct: 1720 WKEPVTSDVPPIGYEIYYVRGDKSVEEDDSAGLNDWIKISIDDPTKLTHKIQNLLLPDTD 1779
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETK---IQSPTVEKPLKNITTE---PNEDIELT 1502
Y F+ A+ S SE K + + IQ T + ++ TT P + +
Sbjct: 1780 YVFKMRAIYPDGPSVFSEPC-IMKTLPDGNAPYIQISTGDNGVEGSTTIQILPGSQMTIA 1838
Query: 1503 CIFGGVPQPKVTWYRDGK-KLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
C G+P P+V W + G ++ ++ + N + C+A N G
Sbjct: 1839 CNATGIPLPQVKWIKAGNYEIDPSRVDADGNHAQFSLQVANITEDTTFNCVAQNPLGHAN 1898
Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPE--VIWYKNGNKLEND 1616
+ V + + ++ + K G LV + E + PP I Y + + D
Sbjct: 1899 WTINVNLIEGLEPNWRDDFVTSKSDGGQIVLVFNDELPEYLKPPNEWTIQYTDDAEQPKD 1958
Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
+ +I + + R++ + + Y + N ++ V P KP +
Sbjct: 1959 QWESIPS-GGAPLTRVEVPNMNPGTFYYLVVDNP--EKGIQTPTLVVMTP-KPPSDIRFG 2014
Query: 1677 EISRESVTIEWKPPLDDGGL-ELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNEN 1734
+ + + +++KP + + E T +P N ++ ADV V + L +
Sbjct: 2015 KNNDDEQIVDFKPAVASEPIKEYTISVWPSTDPSNVKKFTTPADVTSGV---VVDGLEPD 2071
Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKT 1762
EY +V A+ G E L SEP+ +KT
Sbjct: 2072 TEYNVQVAAEFYEG--EELASEPVTVKT 2097
Score = 35.1 bits (77), Expect = 0.55
Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 16/135 (11%)
Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY-KNGNKLENDKEYNITTKEKTS 1628
+P + ED + G ++ + V EG P P+V W +GN+L +
Sbjct: 1499 QPSFNVDTEDGVIRVPAGTDYTIKCVSEGYPAPDVRWVDSHGNQLSDG-----------P 1547
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
++RI +++++ ++K A N G ++T+ V + PE + + +++++++
Sbjct: 1548 LLRIIDIRKTLNAKCL--AENRGGLKETDLTIFVAGPGTAPEN-IQLTANKPTTISVQYE 1604
Query: 1689 PPLDDGGLELTKYAI 1703
P G ++KY I
Sbjct: 1605 VPSIPNG-NISKYII 1618
Score = 34.3 bits (75), Expect = 0.97
Identities = 38/132 (28%), Positives = 54/132 (40%), Gaps = 14/132 (10%)
Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKS-MIVRQGESVILSAQVVGNPRPTITWCKNNKP 774
EG AS P+ + +GE P ++P S V + ++ G P+P + W K N
Sbjct: 1185 EGPASDPVRFETGSGEIPPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWIKAN-- 1242
Query: 775 VKALPTKSDGDT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
G+T S T+ VKD T AEN+ G + + I V P E
Sbjct: 1243 ---------GETVDSATLQLYDLVKDTSA-TCVAENNAGKTQEAVSIQVTGPGTAPNEIV 1292
Query: 834 LFINRFQEITVK 845
L QEI V+
Sbjct: 1293 LLPMPNQEINVE 1304
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 633 PPTFSKKPKAQYVDEGS--DILLECRLVAIPEPDIAWLFKG---EEIVPDENISVAIESD 687
PP +P + E S ++++EC +P+P I WL+ G E+ + + +D
Sbjct: 681 PPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTD 740
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
+ K+ + G T AVN EG + +KI G P I P
Sbjct: 741 AQDR-TRSKLIAQSTTRSGVATCQAVNSEGSDEKKVPVKI-LGPGSAPLGITP 791
Score = 33.9 bits (74), Expect = 1.3
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
GS + C G P PQ+ W + I PS+ D N A ++ + TF
Sbjct: 1832 GSQMTIACNATGIPLPQVKWIKAGNYEIDPSR----VDADGNHAQFSLQVANITEDTTFN 1887
Query: 583 CVAKNAAGFASST 595
CVA+N G A+ T
Sbjct: 1888 CVAQNPLGHANWT 1900
Score = 31.9 bits (69), Expect = 5.2
Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 14/127 (11%)
Query: 1402 DEPENTGNST---IIYYVVEYQEIDTTEWISVKNITKTQT------SI--QNLKTNSSYR 1450
D+PEN G +I Y + + D + W +K T SI +N ++ Y
Sbjct: 1410 DDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFTDPDDTDDTTIVSIDGENFNPDTKYN 1469
Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGV 1508
R A E+D S +E T + P+ ++ I D + C+ G
Sbjct: 1470 TRIIARGEID-SQPNEPTLFATGDGVIAPSQPSFNVDTEDGVIRVPAGTDYTIKCVSEGY 1528
Query: 1509 PQPKVTW 1515
P P V W
Sbjct: 1529 PAPDVRW 1535
Score = 31.1 bits (67), Expect = 9.0
Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD------DDNVATLVIREVFP 575
P + EC +G P+P+I W +I+ ++ YD D + +I +
Sbjct: 696 PSNDEMIIECGAQGVPKPKIIWLWSGTLIEDGKEEFRVYDTTPTDAQDRTRSKLIAQSTT 755
Query: 576 EDAGTFTCVAKNAAG 590
+G TC A N+ G
Sbjct: 756 R-SGVATCQAVNSEG 769
Score = 31.1 bits (67), Expect = 9.0
Identities = 32/159 (20%), Positives = 64/159 (40%), Gaps = 9/159 (5%)
Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
+I GS +T+ + P P +WI + ++ D A +++ T+
Sbjct: 1828 QILPGSQMTIACNATGIPLPQVKWIKAGNY--EIDPSRVDADGNHAQFSLQVANITEDTT 1885
Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICWDE--PE--NTGNST 1411
+ +N GHA+ +NV +++ P + + + + D I + +++ PE N
Sbjct: 1886 FNCVAQNPLGHANWTINVNLIEGLEPNWRDDFVTSKSDGGQIVLVFNDELPEYLKPPNEW 1945
Query: 1412 IIYYVVE-YQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
I Y + Q D E I T+ + N+ + Y
Sbjct: 1946 TIQYTDDAEQPKDQWESIPSGGAPLTRVEVPNMNPGTFY 1984
>AF456361-1|AAL60232.1| 1187|Caenorhabditis elegans immunoglobulin
domain-containingprotein Y54G2A.25 protein.
Length = 1187
Score = 62.5 bits (145), Expect = 3e-09
Identities = 74/322 (22%), Positives = 132/322 (40%), Gaps = 27/322 (8%)
Query: 645 VDEGSDILLECRLV-AIPEPDIAWLFKGEE----IVPDENISVAIESDMHMYCSVLKITN 699
V EG + L C P+P I WL++ + I + + ++++ H++ S +++++
Sbjct: 138 VKEGESLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSD 197
Query: 700 VKK--FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV----IEPLKSMIVRQGESVI 753
K E T + E + I L I+ + + V + P + VR G +
Sbjct: 198 GKATLVYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSP-SEVTVRAGGQLK 256
Query: 754 LSAQVVGNPRPTITWCK--NNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
L G P PTI W K P + T + D I++ D G Y + +
Sbjct: 257 LQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECRGRH 316
Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
+ T V + P E +PP ++I++ E+ T +L P P ITW N
Sbjct: 317 ---LVHTVNVRVMAAPFWE-FDPP------RDISLPEESTGELECLAGGQPTPIITWSMN 366
Query: 870 NEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
+ + +E + L + N++ ++D+G Y+C ASN G A V +
Sbjct: 367 GKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANAFVHVRAHAP 426
Query: 929 TFVKHLQKSYETEEGKTVILEC 950
F + ++ TV+L+C
Sbjct: 427 FFRMPAARHWKVVLHSTVVLDC 448
Score = 38.7 bits (86), Expect = 0.045
Identities = 71/322 (22%), Positives = 123/322 (38%), Gaps = 29/322 (9%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX-XXXXXXXXIDNESVYITWFPSEKN 1794
+Y+ +V + N VG S +E E + DVP I+ ++ TW P + N
Sbjct: 790 KYLIQVQSVNSVGPS-IVEPEIHHGWSGEDVPDEAPRDFHIDTQINFTTINFTWNPVDAN 848
Query: 1795 G-GSPIIDYKVEI-KQEG--KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
+ Y++E K E +K+ I T Y I RN+ S P
Sbjct: 849 TVNGHFVGYEIEYWKAENTIRKYSIKIPANSTYKVINSFHAVTNYSAHIRTRNKRLRSAP 908
Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
D ++ PP + N V S ++ L+W P G I Y I F+ K +
Sbjct: 909 ---SDYVSFAMPEGPPGKVHNLRVYSVGSTAILLQWDAPLQPNGR-IRGYFISFQNEKNE 964
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRIS--AENTVGVSLPTESQSVRLEKHATVPSP 1968
+ V +H + K + + +++S AE G P + VR A +P
Sbjct: 965 TEETYVI---HRQKHYLHE-KSEPDTGYKVSVWAETRAGEG-PVTLRPVRTWP-ARIPDA 1018
Query: 1969 PTAPLEIRMVGSNIVMTSW---GTPEW--DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
P ++ + + + W W G A + Y + +KT W + + +
Sbjct: 1019 PI--FRVKNISLDSFVVEWQPNNHSVWKMPGAAFFVNYT---AESSKT-WFQSEIIYLPY 1072
Query: 2024 LKFNIRDLSENHTYMIRIYARN 2045
+ IR+L E+ Y ++ A++
Sbjct: 1073 TEITIRNLKEDQKYFMQGIAKD 1094
Score = 36.3 bits (80), Expect = 0.24
Identities = 85/443 (19%), Positives = 154/443 (34%), Gaps = 40/443 (9%)
Query: 1047 VVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
+ W + DGE+ K + + R L + N D G Y C R T V V+
Sbjct: 269 IFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAA 328
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG---DALVRWFKDGS---EIQFSNHIQLTIDGK 1159
P + ++ ++T E+E G ++ W +G E+ + L G+
Sbjct: 329 P--FWEFDPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGR 386
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
+++ + DL D G Y C N A + V + F + V ++
Sbjct: 387 ILRVRNLNHDL-DTGVYQCNASNPLGYVFANAFVHVRAHAPFFRMPAARHWKVVLHSTVV 445
Query: 1216 L--TVEIPDETLDVTWY----KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
L V+ E + V W + V+E K T ++ D+ Y C
Sbjct: 446 LDCDVDAAPEAM-VRWVDADDRPLQVVEGKNKL-----FPNHTFMVYDVNSADEGLYYCN 499
Query: 1270 LLDAKSTTKLKVEVVEFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQ-P-NDEWIVN 1324
+ + + + F P + + ++ G + + A P+ P +W +N
Sbjct: 500 VSNKYGINRATNRLQVFKPTYFVRIPTPKRLILEAGETAEVFCEAVADPRLPIRYQWTIN 559
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K++ + ++ + D L + V +GI + M + + D P+ P
Sbjct: 560 GKVLTESQYYEILPD----RLRFRSVRGRHSGIIDCAAITDVDVKLASMQLIVKDVPAHP 615
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQTSIQ 1441
+ W + G+S Y V + + EW + N+ K +
Sbjct: 616 -VVETAHCSERKATVKWVAASDHGDSIKKYIVEMFTDFKKNEWEVINEEVNVNKETFEVD 674
Query: 1442 -NLKTNSSYRFRAYAVNEVDISD 1463
L +Y FR AVN SD
Sbjct: 675 ITLTPWVNYTFRVVAVNSHGRSD 697
Score = 35.1 bits (77), Expect = 0.55
Identities = 43/199 (21%), Positives = 81/199 (40%), Gaps = 13/199 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPSPPGKP-NILEI-DSS 1395
+S+S S+ K + G Y+ N G A +M++ + P + +L + +
Sbjct: 83 ESQSGSIVFTKPHASHQGYYQCFASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGE 142
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
S+ + P T + I++ + E I ++IT + + +A
Sbjct: 143 SLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATL 202
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEK--PLKNITTEPNE-------DIELTCIFG 1506
V E + EY + P+ +K P+K ++ P+E ++L CIFG
Sbjct: 203 VYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFG 262
Query: 1507 GVPQPKVTWYR-DGKKLKT 1524
G P P + W + DG+ K+
Sbjct: 263 GRPLPTIFWSKIDGELPKS 281
Score = 34.7 bits (76), Expect = 0.73
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 3/85 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE-DAGT 580
P+ ST + EC G P P ITW + + D+ L +R + + D G
Sbjct: 342 PEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGV 401
Query: 581 FTCVAKNAAG--FASSTTELIVEAP 603
+ C A N G FA++ + AP
Sbjct: 402 YQCNASNPLGYVFANAFVHVRAHAP 426
Score = 33.9 bits (74), Expect = 1.3
Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY-YDDDNVATLVIREVFPEDAGTFT 582
G ++ +C G P P I W + + S+ + ++ D +L++ V P+DAG +
Sbjct: 252 GGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYE 311
Query: 583 C 583
C
Sbjct: 312 C 312
Score = 32.3 bits (70), Expect = 3.9
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
P ++I+ EL C+ GG P P +TW +GK L
Sbjct: 335 PPRDISLPEESTGELECLAGGQPTPIITWSMNGKFL 370
Score = 31.1 bits (67), Expect = 9.0
Identities = 42/184 (22%), Positives = 77/184 (41%), Gaps = 13/184 (7%)
Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE---NIKEKD 1934
+ R T+KW +G S I YI+E T K+ +++ +V++ E +
Sbjct: 623 SERKATVKWVAASDHGDS-IKKYIVEMFTDFKKNEWEVINEEVNVNKETFEVDITLTPWV 681
Query: 1935 EIIFRISAENTVG---VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS---NIVMTSWG 1988
FR+ A N+ G + + + + L P T P ++ G+ N+V++
Sbjct: 682 NYTFRVVAVNSHGRSDMKIDGQPKEDWLTCQTRPSFPYTNPTGVKGEGTEPDNLVISWKP 741
Query: 1989 TPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKVDVNTLKFN-IRDLSENHTYMIRIYARNE 2046
+ AP + Y + + D W E V+ + F IRD Y+I++ + N
Sbjct: 742 LDRYYWNAPNMQYLVRYKLDEPIHGWTEF-LVEDSLANFTIIRDQPTFRKYLIQVQSVNS 800
Query: 2047 IGLS 2050
+G S
Sbjct: 801 VGPS 804
>AC024817-51|AAP68914.1| 496|Caenorhabditis elegans L1 cam adhesion
molecule homologprotein 2, isoform b protein.
Length = 496
Score = 62.5 bits (145), Expect = 3e-09
Identities = 74/322 (22%), Positives = 132/322 (40%), Gaps = 27/322 (8%)
Query: 645 VDEGSDILLECRLV-AIPEPDIAWLFKGEE----IVPDENISVAIESDMHMYCSVLKITN 699
V EG + L C P+P I WL++ + I + + ++++ H++ S +++++
Sbjct: 138 VKEGESLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSD 197
Query: 700 VKK--FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV----IEPLKSMIVRQGESVI 753
K E T + E + I L I+ + + V + P + VR G +
Sbjct: 198 GKATLVYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSP-SEVTVRAGGQLK 256
Query: 754 LSAQVVGNPRPTITWCK--NNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
L G P PTI W K P + T + D I++ D G Y + +
Sbjct: 257 LQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECRGRH 316
Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
+ T V + P E +PP ++I++ E+ T +L P P ITW N
Sbjct: 317 ---LVHTVNVRVMAAPFWE-FDPP------RDISLPEESTGELECLAGGQPTPIITWSMN 366
Query: 870 NEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
+ + +E + L + N++ ++D+G Y+C ASN G A V +
Sbjct: 367 GKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANAFVHVRAHAP 426
Query: 929 TFVKHLQKSYETEEGKTVILEC 950
F + ++ TV+L+C
Sbjct: 427 FFRMPAARHWKVVLHSTVVLDC 448
Score = 35.1 bits (77), Expect = 0.55
Identities = 43/199 (21%), Positives = 81/199 (40%), Gaps = 13/199 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPSPPGKP-NILEI-DSS 1395
+S+S S+ K + G Y+ N G A +M++ + P + +L + +
Sbjct: 83 ESQSGSIVFTKPHASHQGYYQCFASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGE 142
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
S+ + P T + I++ + E I ++IT + + +A
Sbjct: 143 SLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATL 202
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEK--PLKNITTEPNE-------DIELTCIFG 1506
V E + EY + P+ +K P+K ++ P+E ++L CIFG
Sbjct: 203 VYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFG 262
Query: 1507 GVPQPKVTWYR-DGKKLKT 1524
G P P + W + DG+ K+
Sbjct: 263 GRPLPTIFWSKIDGELPKS 281
Score = 34.7 bits (76), Expect = 0.73
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 3/85 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE-DAGT 580
P+ ST + EC G P P ITW + + D+ L +R + + D G
Sbjct: 342 PEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGV 401
Query: 581 FTCVAKNAAG--FASSTTELIVEAP 603
+ C A N G FA++ + AP
Sbjct: 402 YQCNASNPLGYVFANAFVHVRAHAP 426
Score = 33.9 bits (74), Expect = 1.3
Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY-YDDDNVATLVIREVFPEDAGTFT 582
G ++ +C G P P I W + + S+ + ++ D +L++ V P+DAG +
Sbjct: 252 GGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYE 311
Query: 583 C 583
C
Sbjct: 312 C 312
Score = 32.3 bits (70), Expect = 3.9
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
P ++I+ EL C+ GG P P +TW +GK L
Sbjct: 335 PPRDISLPEESTGELECLAGGQPTPIITWSMNGKFL 370
Score = 31.5 bits (68), Expect = 6.8
Identities = 33/143 (23%), Positives = 56/143 (39%), Gaps = 10/143 (6%)
Query: 1047 VVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
+ W + DGE+ K + + R L + N D G Y C R T V V+
Sbjct: 269 IFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAA 328
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG---DALVRWFKDGS---EIQFSNHIQLTIDGK 1159
P + ++ ++T E+E G ++ W +G E+ + L G+
Sbjct: 329 P--FWEFDPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGR 386
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGN 1182
+++ + DL D G Y C N
Sbjct: 387 ILRVRNLNHDL-DTGVYQCNASN 408
>AC024817-49|AAF59572.3| 1187|Caenorhabditis elegans L1 cam adhesion
molecule homologprotein 2, isoform a protein.
Length = 1187
Score = 62.5 bits (145), Expect = 3e-09
Identities = 74/322 (22%), Positives = 132/322 (40%), Gaps = 27/322 (8%)
Query: 645 VDEGSDILLECRLV-AIPEPDIAWLFKGEE----IVPDENISVAIESDMHMYCSVLKITN 699
V EG + L C P+P I WL++ + I + + ++++ H++ S +++++
Sbjct: 138 VKEGESLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSD 197
Query: 700 VKK--FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV----IEPLKSMIVRQGESVI 753
K E T + E + I L I+ + + V + P + VR G +
Sbjct: 198 GKATLVYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSP-SEVTVRAGGQLK 256
Query: 754 LSAQVVGNPRPTITWCK--NNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
L G P PTI W K P + T + D I++ D G Y + +
Sbjct: 257 LQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECRGRH 316
Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
+ T V + P E +PP ++I++ E+ T +L P P ITW N
Sbjct: 317 ---LVHTVNVRVMAAPFWE-FDPP------RDISLPEESTGELECLAGGQPTPIITWSMN 366
Query: 870 NEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
+ + +E + L + N++ ++D+G Y+C ASN G A V +
Sbjct: 367 GKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANAFVHVRAHAP 426
Query: 929 TFVKHLQKSYETEEGKTVILEC 950
F + ++ TV+L+C
Sbjct: 427 FFRMPAARHWKVVLHSTVVLDC 448
Score = 38.7 bits (86), Expect = 0.045
Identities = 71/322 (22%), Positives = 123/322 (38%), Gaps = 29/322 (9%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX-XXXXXXXXIDNESVYITWFPSEKN 1794
+Y+ +V + N VG S +E E + DVP I+ ++ TW P + N
Sbjct: 790 KYLIQVQSVNSVGPS-IVEPEIHHGWSGEDVPDEAPRDFHIDTQINFTTINFTWNPVDAN 848
Query: 1795 G-GSPIIDYKVEI-KQEG--KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
+ Y++E K E +K+ I T Y I RN+ S P
Sbjct: 849 TVNGHFVGYEIEYWKAENTIRKYSIKIPANSTYKVINSFHAVTNYSAHIRTRNKRLRSAP 908
Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
D ++ PP + N V S ++ L+W P G I Y I F+ K +
Sbjct: 909 ---SDYVSFAMPEGPPGKVHNLRVYSVGSTAILLQWDAPLQPNGR-IRGYFISFQNEKNE 964
Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRIS--AENTVGVSLPTESQSVRLEKHATVPSP 1968
+ V +H + K + + +++S AE G P + VR A +P
Sbjct: 965 TEETYVI---HRQKHYLHE-KSEPDTGYKVSVWAETRAGEG-PVTLRPVRTWP-ARIPDA 1018
Query: 1969 PTAPLEIRMVGSNIVMTSW---GTPEW--DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
P ++ + + + W W G A + Y + +KT W + + +
Sbjct: 1019 PI--FRVKNISLDSFVVEWQPNNHSVWKMPGAAFFVNYT---AESSKT-WFQSEIIYLPY 1072
Query: 2024 LKFNIRDLSENHTYMIRIYARN 2045
+ IR+L E+ Y ++ A++
Sbjct: 1073 TEITIRNLKEDQKYFMQGIAKD 1094
Score = 36.3 bits (80), Expect = 0.24
Identities = 85/443 (19%), Positives = 154/443 (34%), Gaps = 40/443 (9%)
Query: 1047 VVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
+ W + DGE+ K + + R L + N D G Y C R T V V+
Sbjct: 269 IFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAA 328
Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG---DALVRWFKDGS---EIQFSNHIQLTIDGK 1159
P + ++ ++T E+E G ++ W +G E+ + L G+
Sbjct: 329 P--FWEFDPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGR 386
Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
+++ + DL D G Y C N A + V + F + V ++
Sbjct: 387 ILRVRNLNHDL-DTGVYQCNASNPLGYVFANAFVHVRAHAPFFRMPAARHWKVVLHSTVV 445
Query: 1216 L--TVEIPDETLDVTWY----KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
L V+ E + V W + V+E K T ++ D+ Y C
Sbjct: 446 LDCDVDAAPEAM-VRWVDADDRPLQVVEGKNKL-----FPNHTFMVYDVNSADEGLYYCN 499
Query: 1270 LLDAKSTTKLKVEVVEFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQ-P-NDEWIVN 1324
+ + + + F P + + ++ G + + A P+ P +W +N
Sbjct: 500 VSNKYGINRATNRLQVFKPTYFVRIPTPKRLILEAGETAEVFCEAVADPRLPIRYQWTIN 559
Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
K++ + ++ + D L + V +GI + M + + D P+ P
Sbjct: 560 GKVLTESQYYEILPD----RLRFRSVRGRHSGIIDCAAITDVDVKLASMQLIVKDVPAHP 615
Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQTSIQ 1441
+ W + G+S Y V + + EW + N+ K +
Sbjct: 616 -VVETAHCSERKATVKWVAASDHGDSIKKYIVEMFTDFKKNEWEVINEEVNVNKETFEVD 674
Query: 1442 -NLKTNSSYRFRAYAVNEVDISD 1463
L +Y FR AVN SD
Sbjct: 675 ITLTPWVNYTFRVVAVNSHGRSD 697
Score = 35.1 bits (77), Expect = 0.55
Identities = 43/199 (21%), Positives = 81/199 (40%), Gaps = 13/199 (6%)
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPSPPGKP-NILEI-DSS 1395
+S+S S+ K + G Y+ N G A +M++ + P + +L + +
Sbjct: 83 ESQSGSIVFTKPHASHQGYYQCFASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGE 142
Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
S+ + P T + I++ + E I ++IT + + +A
Sbjct: 143 SLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATL 202
Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEK--PLKNITTEPNE-------DIELTCIFG 1506
V E + EY + P+ +K P+K ++ P+E ++L CIFG
Sbjct: 203 VYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFG 262
Query: 1507 GVPQPKVTWYR-DGKKLKT 1524
G P P + W + DG+ K+
Sbjct: 263 GRPLPTIFWSKIDGELPKS 281
Score = 34.7 bits (76), Expect = 0.73
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 3/85 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE-DAGT 580
P+ ST + EC G P P ITW + + D+ L +R + + D G
Sbjct: 342 PEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGV 401
Query: 581 FTCVAKNAAG--FASSTTELIVEAP 603
+ C A N G FA++ + AP
Sbjct: 402 YQCNASNPLGYVFANAFVHVRAHAP 426
Score = 33.9 bits (74), Expect = 1.3
Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY-YDDDNVATLVIREVFPEDAGTFT 582
G ++ +C G P P I W + + S+ + ++ D +L++ V P+DAG +
Sbjct: 252 GGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYE 311
Query: 583 C 583
C
Sbjct: 312 C 312
Score = 32.3 bits (70), Expect = 3.9
Identities = 14/36 (38%), Positives = 20/36 (55%)
Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
P ++I+ EL C+ GG P P +TW +GK L
Sbjct: 335 PPRDISLPEESTGELECLAGGQPTPIITWSMNGKFL 370
Score = 31.1 bits (67), Expect = 9.0
Identities = 42/184 (22%), Positives = 77/184 (41%), Gaps = 13/184 (7%)
Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE---NIKEKD 1934
+ R T+KW +G S I YI+E T K+ +++ +V++ E +
Sbjct: 623 SERKATVKWVAASDHGDS-IKKYIVEMFTDFKKNEWEVINEEVNVNKETFEVDITLTPWV 681
Query: 1935 EIIFRISAENTVG---VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS---NIVMTSWG 1988
FR+ A N+ G + + + + L P T P ++ G+ N+V++
Sbjct: 682 NYTFRVVAVNSHGRSDMKIDGQPKEDWLTCQTRPSFPYTNPTGVKGEGTEPDNLVISWKP 741
Query: 1989 TPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKVDVNTLKFN-IRDLSENHTYMIRIYARNE 2046
+ AP + Y + + D W E V+ + F IRD Y+I++ + N
Sbjct: 742 LDRYYWNAPNMQYLVRYKLDEPIHGWTEF-LVEDSLANFTIIRDQPTFRKYLIQVQSVNS 800
Query: 2047 IGLS 2050
+G S
Sbjct: 801 VGPS 804
>Z68006-8|CAA91999.1| 1328|Caenorhabditis elegans Hypothetical
protein K09C8.5 protein.
Length = 1328
Score = 62.1 bits (144), Expect = 4e-09
Identities = 52/214 (24%), Positives = 85/214 (39%), Gaps = 9/214 (4%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
+G + L+C P P I WLF+ +++ + SVLKI G
Sbjct: 365 DGETLELKCEASGEPTPTITWLFEKQKLTESRKHKLTKNG------SVLKIFPFLNTDIG 418
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
Y VA N GE S + + E E P +I+ G+ V L G P P +
Sbjct: 419 QYECVASN--GEESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDV 476
Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLKAENSEGIAETSAVITVEEP 825
W + T+ ++I + K + D GV+T +A NS G A +A + V
Sbjct: 477 VWLFEGIRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLVGAE 536
Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
E + L + ++I + K ++ T++
Sbjct: 537 LTEKVDKLLDDSTIEKIAKEAKQKVEKALSSTKD 570
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
Query: 459 QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP 518
+KH + G V + + QY N + K +F S ++S P+ ++
Sbjct: 396 RKHKLTKNGSVLKIFPFLNTDIGQYECVASNGEESKSHIFS--VSLKESEQPVIIDAPMD 453
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
+ G V C +G+P P + W + I P ++ + D+N+ L I +V D+
Sbjct: 454 TNATIGQQVTLRCNAKGFPVPDVVWLFEGIRI-PRRNTRYTISDNNIE-LTIEKVTRHDS 511
Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLSD 606
G FTC A N+ G A +T L+V A L++
Sbjct: 512 GVFTCQAVNSVGSAVATANLLVGAELTE 539
Score = 57.2 bits (132), Expect = 1e-07
Identities = 42/206 (20%), Positives = 82/206 (39%), Gaps = 4/206 (1%)
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
+D D +E+ + E + K L + T+ E +EL C G P P +TW +
Sbjct: 330 MDSMDTTESVVTMTTMPEIDTKIVFEHKQL-DTTSRDGETLELKCEASGEPTPTITWLFE 388
Query: 1519 GKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
+KL ++ +N Y+C+A N V +++ I
Sbjct: 389 KQKLTESRKHKLTKNGSVLKIFPFLNTDIGQYECVASNGEESKSHIFSVSLKESEQPVII 448
Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
+ + +G + + +G P P+V+W G ++ + T + + I+++
Sbjct: 449 DAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRIPR-RNTRYTISDNNIELTIEKVT 507
Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKV 1662
R S +T +A N+ G++ L V
Sbjct: 508 RHDSGVFTCQAVNSVGSAVATANLLV 533
Score = 55.2 bits (127), Expect = 5e-07
Identities = 50/182 (27%), Positives = 74/182 (40%), Gaps = 11/182 (6%)
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYT 804
R GE++ L + G P PTITW + K ++ T + ++LK P D G Y
Sbjct: 364 RDGETLELKCEASGEPTPTITWLFEKQ--KLTESRKHKLTKNGSVLKIFPFLNTDIGQYE 421
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N E S + +V + + +E P+ I+ + + L PVP +
Sbjct: 422 CVASNGE--ESKSHIFSV---SLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDV 476
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
W I P NIEL I V + DSG + C A NS G + A + +
Sbjct: 477 VWLFEG-IRIPRRNTRYTISDNNIELTIEKV-TRHDSGVFTCQAVNSVGSAVATANLLVG 534
Query: 925 VE 926
E
Sbjct: 535 AE 536
Score = 52.0 bits (119), Expect = 5e-06
Identities = 39/159 (24%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--L 1279
+ T +TW +K + ++ K L + L I D +Y CV + + +
Sbjct: 378 EPTPTITWLFEKQKLTESRKHKLTKNGS--VLKIFPFLNTDIGQYECVASNGEESKSHIF 435
Query: 1280 KVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
V + E P I+D + G VTL + + FP P+ W+ I + ++T+ +I
Sbjct: 436 SVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRIPR-RNTRYTI 494
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ LTI+KV D+G++ + N+ G A N+ +
Sbjct: 495 SDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLV 533
Score = 43.6 bits (98), Expect = 0.002
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E P P G + L C P PD+ WLF+G I P N I SD +
Sbjct: 441 ESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRI-PRRNTRYTI-SDNN 498
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
+ ++ K+T + G +T AVN G A
Sbjct: 499 IELTIEKVT---RHDSGVFTCQAVNSVGSA 525
Score = 41.1 bits (92), Expect = 0.008
Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
T +V+T+ E + + +F ++ + T ++ T++L + P P+ITW + ++
Sbjct: 336 TESVVTMTTMPEIDTKI-VFEHKQLDTTSRDGETLELKCEASGEPTPTITWLFEKQKLTE 394
Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
S +G ++ + ++++I G Y+CVASN SH V++ + +
Sbjct: 395 SRKHKLTKNGSVLK-IFPFLNTDI--GQYECVASNGEESKSHIFSVSLKESEQPVIIDAP 451
Query: 936 KSYETEEGKTVILEC 950
G+ V L C
Sbjct: 452 MDTNATIGQQVTLRC 466
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
+F K + DG T++ +C+ G P P ITW + + S+ ++ N + L I
Sbjct: 353 VFEHKQLDTTSRDGETLELKCEASGEPTPTITWLFEKQKLTESRKHKL---TKNGSVLKI 409
Query: 571 REVFPEDAGTFTCVAKN 587
D G + CVA N
Sbjct: 410 FPFLNTDIGQYECVASN 426
Score = 39.5 bits (88), Expect = 0.026
Identities = 50/202 (24%), Positives = 85/202 (42%), Gaps = 23/202 (11%)
Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-------LEVEINSE-TADVVWERDGEII 1056
+T+ +V T+PE K+ FE K+ D L+ E + E T + W + + +
Sbjct: 334 DTTESVVTMTTMPEIDTKIV-FEHKQLDTTSRDGETLELKCEASGEPTPTITWLFEKQKL 392
Query: 1057 KPKKNKYDFEKRGHIRKLY-IRNTSVHDEGEYSCILRD-ESCTAEVTVVELP----PEII 1110
+ K+ K G + K++ NT + G+Y C+ + E + + V L P II
Sbjct: 393 TESR-KHKLTKNGSVLKIFPFLNTDI---GQYECVASNGEESKSHIFSVSLKESEQPVII 448
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
+ G + T KG + V W +G I N + TI +L I
Sbjct: 449 DAPMDTNATIGQQVTLRCN-AKGFPVPDVVWLFEGIRIPRRN-TRYTISDNNIELTIEKV 506
Query: 1169 DLDDAGEYSCEVGNSKCTAILT 1190
D+G ++C+ NS +A+ T
Sbjct: 507 TRHDSGVFTCQAVNSVGSAVAT 528
>Z68005-6|CAA91994.1| 1328|Caenorhabditis elegans Hypothetical
protein K09C8.5 protein.
Length = 1328
Score = 62.1 bits (144), Expect = 4e-09
Identities = 52/214 (24%), Positives = 85/214 (39%), Gaps = 9/214 (4%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
+G + L+C P P I WLF+ +++ + SVLKI G
Sbjct: 365 DGETLELKCEASGEPTPTITWLFEKQKLTESRKHKLTKNG------SVLKIFPFLNTDIG 418
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
Y VA N GE S + + E E P +I+ G+ V L G P P +
Sbjct: 419 QYECVASN--GEESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDV 476
Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLKAENSEGIAETSAVITVEEP 825
W + T+ ++I + K + D GV+T +A NS G A +A + V
Sbjct: 477 VWLFEGIRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLVGAE 536
Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
E + L + ++I + K ++ T++
Sbjct: 537 LTEKVDKLLDDSTIEKIAKEAKQKVEKALSSTKD 570
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
Query: 459 QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP 518
+KH + G V + + QY N + K +F S ++S P+ ++
Sbjct: 396 RKHKLTKNGSVLKIFPFLNTDIGQYECVASNGEESKSHIFS--VSLKESEQPVIIDAPMD 453
Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
+ G V C +G+P P + W + I P ++ + D+N+ L I +V D+
Sbjct: 454 TNATIGQQVTLRCNAKGFPVPDVVWLFEGIRI-PRRNTRYTISDNNIE-LTIEKVTRHDS 511
Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLSD 606
G FTC A N+ G A +T L+V A L++
Sbjct: 512 GVFTCQAVNSVGSAVATANLLVGAELTE 539
Score = 57.2 bits (132), Expect = 1e-07
Identities = 42/206 (20%), Positives = 82/206 (39%), Gaps = 4/206 (1%)
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
+D D +E+ + E + K L + T+ E +EL C G P P +TW +
Sbjct: 330 MDSMDTTESVVTMTTMPEIDTKIVFEHKQL-DTTSRDGETLELKCEASGEPTPTITWLFE 388
Query: 1519 GKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
+KL ++ +N Y+C+A N V +++ I
Sbjct: 389 KQKLTESRKHKLTKNGSVLKIFPFLNTDIGQYECVASNGEESKSHIFSVSLKESEQPVII 448
Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
+ + +G + + +G P P+V+W G ++ + T + + I+++
Sbjct: 449 DAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRIPR-RNTRYTISDNNIELTIEKVT 507
Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKV 1662
R S +T +A N+ G++ L V
Sbjct: 508 RHDSGVFTCQAVNSVGSAVATANLLV 533
Score = 55.2 bits (127), Expect = 5e-07
Identities = 50/182 (27%), Positives = 74/182 (40%), Gaps = 11/182 (6%)
Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYT 804
R GE++ L + G P PTITW + K ++ T + ++LK P D G Y
Sbjct: 364 RDGETLELKCEASGEPTPTITWLFEKQ--KLTESRKHKLTKNGSVLKIFPFLNTDIGQYE 421
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
A N E S + +V + + +E P+ I+ + + L PVP +
Sbjct: 422 CVASNGE--ESKSHIFSV---SLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDV 476
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
W I P NIEL I V + DSG + C A NS G + A + +
Sbjct: 477 VWLFEG-IRIPRRNTRYTISDNNIELTIEKV-TRHDSGVFTCQAVNSVGSAVATANLLVG 534
Query: 925 VE 926
E
Sbjct: 535 AE 536
Score = 52.0 bits (119), Expect = 5e-06
Identities = 39/159 (24%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--L 1279
+ T +TW +K + ++ K L + L I D +Y CV + + +
Sbjct: 378 EPTPTITWLFEKQKLTESRKHKLTKNGS--VLKIFPFLNTDIGQYECVASNGEESKSHIF 435
Query: 1280 KVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
V + E P I+D + G VTL + + FP P+ W+ I + ++T+ +I
Sbjct: 436 SVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRIPR-RNTRYTI 494
Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
+ LTI+KV D+G++ + N+ G A N+ +
Sbjct: 495 SDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLV 533
Score = 43.6 bits (98), Expect = 0.002
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
E P P G + L C P PD+ WLF+G I P N I SD +
Sbjct: 441 ESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRI-PRRNTRYTI-SDNN 498
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
+ ++ K+T + G +T AVN G A
Sbjct: 499 IELTIEKVT---RHDSGVFTCQAVNSVGSA 525
Score = 41.1 bits (92), Expect = 0.008
Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
T +V+T+ E + + +F ++ + T ++ T++L + P P+ITW + ++
Sbjct: 336 TESVVTMTTMPEIDTKI-VFEHKQLDTTSRDGETLELKCEASGEPTPTITWLFEKQKLTE 394
Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
S +G ++ + ++++I G Y+CVASN SH V++ + +
Sbjct: 395 SRKHKLTKNGSVLK-IFPFLNTDI--GQYECVASNGEESKSHIFSVSLKESEQPVIIDAP 451
Query: 936 KSYETEEGKTVILEC 950
G+ V L C
Sbjct: 452 MDTNATIGQQVTLRC 466
Score = 40.7 bits (91), Expect = 0.011
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
+F K + DG T++ +C+ G P P ITW + + S+ ++ N + L I
Sbjct: 353 VFEHKQLDTTSRDGETLELKCEASGEPTPTITWLFEKQKLTESRKHKL---TKNGSVLKI 409
Query: 571 REVFPEDAGTFTCVAKN 587
D G + CVA N
Sbjct: 410 FPFLNTDIGQYECVASN 426
Score = 39.5 bits (88), Expect = 0.026
Identities = 50/202 (24%), Positives = 85/202 (42%), Gaps = 23/202 (11%)
Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-------LEVEINSE-TADVVWERDGEII 1056
+T+ +V T+PE K+ FE K+ D L+ E + E T + W + + +
Sbjct: 334 DTTESVVTMTTMPEIDTKIV-FEHKQLDTTSRDGETLELKCEASGEPTPTITWLFEKQKL 392
Query: 1057 KPKKNKYDFEKRGHIRKLY-IRNTSVHDEGEYSCILRD-ESCTAEVTVVELP----PEII 1110
+ K+ K G + K++ NT + G+Y C+ + E + + V L P II
Sbjct: 393 TESR-KHKLTKNGSVLKIFPFLNTDI---GQYECVASNGEESKSHIFSVSLKESEQPVII 448
Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
+ G + T KG + V W +G I N + TI +L I
Sbjct: 449 DAPMDTNATIGQQVTLRCN-AKGFPVPDVVWLFEGIRIPRRN-TRYTISDNNIELTIEKV 506
Query: 1169 DLDDAGEYSCEVGNSKCTAILT 1190
D+G ++C+ NS +A+ T
Sbjct: 507 TRHDSGVFTCQAVNSVGSAVAT 528
>U49830-6|AAK31481.1| 964|Caenorhabditis elegans Neuronal igcam
protein 6, isoform a protein.
Length = 964
Score = 61.3 bits (142), Expect = 7e-09
Identities = 79/328 (24%), Positives = 129/328 (39%), Gaps = 33/328 (10%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P F + PK G I LEC A P P W + +P S + Y
Sbjct: 123 PQIFPEDPKV-----GDSIYLECFAYASPLPQYKWSRVDGKPIP-------ARSHISNYG 170
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
VLKI V G Y VA+N G A+ + +K++ PP +++ L +V +V
Sbjct: 171 RVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRA----PPSILQGLHDRLVPTESNV 226
Query: 753 ILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGD-----THSITILKPKKVKDEGVYTLK 806
+ + ++ W K+ KP+ L ++ H++ LK D GVY
Sbjct: 227 SFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCV 286
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G + +SA++TV++ PP ++R ++ T+ + +P W
Sbjct: 287 ASNDVGSSSSSALLTVKDSAP--VFPPNAMSR--KVFAAFGSTVSIPCIFEASPRFHGKW 342
Query: 867 YRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
P + ++ +G +IE V+ D+G + C A N GK +H I V
Sbjct: 343 ADAGGSKLPQKGRIRDEEGVISIEKVLHE-----DAGLFFCTAHNKLGK-AHAQVQLIVV 396
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS 953
K + + V L C+ S
Sbjct: 397 NKPSIKTNFLDEETVNMSCEVELTCENS 424
Score = 50.4 bits (115), Expect = 1e-05
Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 749 GESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTL 805
G+S+ L +P P W + + KP+ P +S + +LK +KV D G Y
Sbjct: 133 GDSIYLECFAYASPLPQYKWSRVDGKPI---PARSHISNYG-RVLKIEKVNYGDAGKYKC 188
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NPVPSI 864
A N+ G A + + P P + + V + + ++ + S+
Sbjct: 189 VAMNAFGSAAGEVHVKLRAP-------PSILQGLHDRLVPTESNVSFECLLSNADSYSSV 241
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVD--SEIDSGDYKCVASNSAGKSSHGARVT 922
W+++ + I P + I+ + ++ E DSG Y+CVASN G SS A +T
Sbjct: 242 EWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLT 301
Query: 923 IDVEKVTFVKH-LQKSYETEEGKTVILEC--QTSHTVSTKW 960
+ F + + + G TV + C + S KW
Sbjct: 302 VKDSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKW 342
Score = 46.4 bits (105), Expect = 2e-04
Identities = 69/280 (24%), Positives = 119/280 (42%), Gaps = 35/280 (12%)
Query: 1138 RWFK-DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE---- 1192
+W + DG I +HI + LKI + DAG+Y C N+ +A V
Sbjct: 151 KWSRVDGKPIPARSHIS----NYGRVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLR 206
Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIE---DTEKFTLISD 1247
PSI L + +N + D V W+K K ++ EK +
Sbjct: 207 APPSILQGLH-DRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLK- 264
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVE-----FPPKIVDYEREYRIKR 1301
+ L ++ E D Y CV D S++ + V+ FPP + R+
Sbjct: 265 IDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFPPNAMS--RKVFAAF 322
Query: 1302 GSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
GS V++ ++A P+ + +W SK+ +K + I + ++I+KV + DAG++
Sbjct: 323 GSTVSIPCIFEASPRFHGKWADAGGSKLPQKGR-----IRDEEGVISIEKVLHEDAGLFF 377
Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
N G A ++ + +++KPS K N L D ++N+
Sbjct: 378 CTAHNKLGKAHAQVQLIVVNKPSI--KTNFL--DEETVNM 413
Score = 39.5 bits (88), Expect = 0.026
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 4/88 (4%)
Query: 518 PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
P+ G ++ EC P PQ W R P++ Y L I +V D
Sbjct: 127 PEDPKVGDSIYLECFAYASPLPQYKWSRVDGKPIPARSHISNYG----RVLKIEKVNYGD 182
Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLS 605
AG + CVA NA G A+ + + AP S
Sbjct: 183 AGKYKCVAMNAFGSAAGEVHVKLRAPPS 210
Score = 37.9 bits (84), Expect = 0.078
Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
GSTV C E PR W P + D++ V + I +V EDAG F C
Sbjct: 323 GSTVSIPCIFEASPRFHGKWADAGGSKLPQKG--RIRDEEGVIS--IEKVLHEDAGLFFC 378
Query: 584 VAKNAAGFASSTTELIV 600
A N G A + +LIV
Sbjct: 379 TAHNKLGKAHAQVQLIV 395
Score = 37.5 bits (83), Expect = 0.10
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPR-PQITWFRQTA----IIKPSQDFQMYYDDDN 564
P ++ L + P S V FEC + + WF+ ++ P++ + D N
Sbjct: 209 PSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHN 268
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V L + D+G + CVA N G +SS+ L V+
Sbjct: 269 VLHLKFAD--ETDSGVYQCVASNDVGSSSSSALLTVK 303
Score = 36.7 bits (81), Expect = 0.18
Identities = 108/538 (20%), Positives = 188/538 (34%), Gaps = 43/538 (7%)
Query: 1286 FPPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
FPPK+ + + K G + L A P P +W S++ K + I +
Sbjct: 114 FPPKLDSTQPQIFPEDPKVGDSIYLECFAYASPLPQYKW---SRVDGKPIPARSHISNYG 170
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICW 1401
L I+KV DAG YK N G A E++V + PS G + L S+++
Sbjct: 171 RVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRAPPSILQGLHDRLVPTESNVSFEC 230
Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK---TNSSYRFRAYAVNE 1458
S++ ++ + + K ++ +LK S ++ A N+
Sbjct: 231 LLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASND 290
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-R 1517
V S +S +K++ P K + + + CIF P+ W
Sbjct: 291 VGSSSSSALL----TVKDSAPVFPPNAMSRK-VFAAFGSTVSIPCIFEASPRFHGKWADA 345
Query: 1518 DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577
G KL + + C A N G+ + + KP I +
Sbjct: 346 GGSKLPQKGRIRDEEGVISIEKVLHEDAGLFFCTAHNKLGKAHAQVQLIVVNKPSIKTNF 405
Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
D + + + L P W N + EK S + + LK+
Sbjct: 406 LDEETVNMSCEVELTCENSAECPEALFEWKINDRPAKEYPSLKSKVHEKKSGHKGRHLKQ 465
Query: 1638 SHSSKY--TIEASNTAG----TSSVEVTLKVYDKPSKPEGPVIMREISRES------VTI 1685
+ ++ S G +S + + KP P + E E +
Sbjct: 466 KVDLEVPKSLAGSRQIGRFACSSLYGGSSEFVTKPQLPSPIALTVEQMDEDGKKKKMFRL 525
Query: 1686 EWK-PPLD----DGGLELTKYAIEKHEPDNNRWIK-----VADVDRDVETYCIQKLNENC 1735
W+ PP D ++ Y +E N +W V ++++D T ++ L N
Sbjct: 526 RWRLPPQHRDTRDHSPKVEGYLVELRTRKNRKWRAAERQLVGNMEKDSIT--VENLLPNT 583
Query: 1736 EYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
EY FRV + E ++ S+ +KTA PS +D++++ + W P E
Sbjct: 584 EYQFRVRSVESAAIGEPSIPSD--WVKTAPGAPSETIDNLKWRSLDSQTLLVEWQPIE 639
>U49830-5|AAK31482.1| 1227|Caenorhabditis elegans Neuronal igcam
protein 6, isoform b protein.
Length = 1227
Score = 61.3 bits (142), Expect = 7e-09
Identities = 79/328 (24%), Positives = 129/328 (39%), Gaps = 33/328 (10%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P F + PK G I LEC A P P W + +P S + Y
Sbjct: 386 PQIFPEDPKV-----GDSIYLECFAYASPLPQYKWSRVDGKPIP-------ARSHISNYG 433
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
VLKI V G Y VA+N G A+ + +K++ PP +++ L +V +V
Sbjct: 434 RVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRA----PPSILQGLHDRLVPTESNV 489
Query: 753 ILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGD-----THSITILKPKKVKDEGVYTLK 806
+ + ++ W K+ KP+ L ++ H++ LK D GVY
Sbjct: 490 SFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCV 549
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G + +SA++TV++ PP ++R ++ T+ + +P W
Sbjct: 550 ASNDVGSSSSSALLTVKDSAP--VFPPNAMSR--KVFAAFGSTVSIPCIFEASPRFHGKW 605
Query: 867 YRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
P + ++ +G +IE V+ D+G + C A N GK +H I V
Sbjct: 606 ADAGGSKLPQKGRIRDEEGVISIEKVLHE-----DAGLFFCTAHNKLGK-AHAQVQLIVV 659
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS 953
K + + V L C+ S
Sbjct: 660 NKPSIKTNFLDEETVNMSCEVELTCENS 687
Score = 50.4 bits (115), Expect = 1e-05
Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 749 GESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTL 805
G+S+ L +P P W + + KP+ P +S + +LK +KV D G Y
Sbjct: 396 GDSIYLECFAYASPLPQYKWSRVDGKPI---PARSHISNYG-RVLKIEKVNYGDAGKYKC 451
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NPVPSI 864
A N+ G A + + P P + + V + + ++ + S+
Sbjct: 452 VAMNAFGSAAGEVHVKLRAP-------PSILQGLHDRLVPTESNVSFECLLSNADSYSSV 504
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVD--SEIDSGDYKCVASNSAGKSSHGARVT 922
W+++ + I P + I+ + ++ E DSG Y+CVASN G SS A +T
Sbjct: 505 EWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLT 564
Query: 923 IDVEKVTFVKH-LQKSYETEEGKTVILEC--QTSHTVSTKW 960
+ F + + + G TV + C + S KW
Sbjct: 565 VKDSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKW 605
Score = 46.4 bits (105), Expect = 2e-04
Identities = 69/280 (24%), Positives = 119/280 (42%), Gaps = 35/280 (12%)
Query: 1138 RWFK-DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE---- 1192
+W + DG I +HI + LKI + DAG+Y C N+ +A V
Sbjct: 414 KWSRVDGKPIPARSHIS----NYGRVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLR 469
Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIE---DTEKFTLISD 1247
PSI L + +N + D V W+K K ++ EK +
Sbjct: 470 APPSILQGLH-DRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLK- 527
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVE-----FPPKIVDYEREYRIKR 1301
+ L ++ E D Y CV D S++ + V+ FPP + R+
Sbjct: 528 IDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFPPNAMS--RKVFAAF 585
Query: 1302 GSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
GS V++ ++A P+ + +W SK+ +K + I + ++I+KV + DAG++
Sbjct: 586 GSTVSIPCIFEASPRFHGKWADAGGSKLPQKGR-----IRDEEGVISIEKVLHEDAGLFF 640
Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
N G A ++ + +++KPS K N L D ++N+
Sbjct: 641 CTAHNKLGKAHAQVQLIVVNKPSI--KTNFL--DEETVNM 676
Score = 39.9 bits (89), Expect = 0.019
Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 11/137 (8%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKL---RPKHTPD----GSTVQ 528
DE++Y L + P F +S + + F KL +P+ P+ G ++
Sbjct: 341 DEDSYACSLSVYSTQSGHYGPFFRLISSTPKLVNSTFPPKLDSTQPQIFPEDPKVGDSIY 400
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
EC P PQ W R P++ Y L I +V DAG + CVA NA
Sbjct: 401 LECFAYASPLPQYKWSRVDGKPIPARSHISNYG----RVLKIEKVNYGDAGKYKCVAMNA 456
Query: 589 AGFASSTTELIVEAPLS 605
G A+ + + AP S
Sbjct: 457 FGSAAGEVHVKLRAPPS 473
Score = 38.3 bits (85), Expect = 0.059
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 850 IKLVARVTRNPVPSITWYRNN-EIISPS-ETITQNFDGENIELVITNVDSEIDSGDYKCV 907
I L V NP P++ WY+N+ E++SPS ++ G N+ + S + + C
Sbjct: 196 IALPCTVQGNPKPTVAWYKNDVEVLSPSMSNVSYLLSGGNL---LVPASSTLAYSSFHCT 252
Query: 908 ASNSAGK 914
A NS G+
Sbjct: 253 ARNSLGE 259
Score = 37.9 bits (84), Expect = 0.078
Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
GSTV C E PR W P + D++ V + I +V EDAG F C
Sbjct: 586 GSTVSIPCIFEASPRFHGKWADAGGSKLPQKG--RIRDEEGVIS--IEKVLHEDAGLFFC 641
Query: 584 VAKNAAGFASSTTELIV 600
A N G A + +LIV
Sbjct: 642 TAHNKLGKAHAQVQLIV 658
Score = 37.5 bits (83), Expect = 0.10
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPR-PQITWFRQTA----IIKPSQDFQMYYDDDN 564
P ++ L + P S V FEC + + WF+ ++ P++ + D N
Sbjct: 472 PSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHN 531
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V L + D+G + CVA N G +SS+ L V+
Sbjct: 532 VLHLKFAD--ETDSGVYQCVASNDVGSSSSSALLTVK 566
Score = 36.7 bits (81), Expect = 0.18
Identities = 108/538 (20%), Positives = 188/538 (34%), Gaps = 43/538 (7%)
Query: 1286 FPPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
FPPK+ + + K G + L A P P +W S++ K + I +
Sbjct: 377 FPPKLDSTQPQIFPEDPKVGDSIYLECFAYASPLPQYKW---SRVDGKPIPARSHISNYG 433
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICW 1401
L I+KV DAG YK N G A E++V + PS G + L S+++
Sbjct: 434 RVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRAPPSILQGLHDRLVPTESNVSFEC 493
Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK---TNSSYRFRAYAVNE 1458
S++ ++ + + K ++ +LK S ++ A N+
Sbjct: 494 LLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASND 553
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-R 1517
V S +S +K++ P K + + + CIF P+ W
Sbjct: 554 VGSSSSSALL----TVKDSAPVFPPNAMSRK-VFAAFGSTVSIPCIFEASPRFHGKWADA 608
Query: 1518 DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577
G KL + + C A N G+ + + KP I +
Sbjct: 609 GGSKLPQKGRIRDEEGVISIEKVLHEDAGLFFCTAHNKLGKAHAQVQLIVVNKPSIKTNF 668
Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
D + + + L P W N + EK S + + LK+
Sbjct: 669 LDEETVNMSCEVELTCENSAECPEALFEWKINDRPAKEYPSLKSKVHEKKSGHKGRHLKQ 728
Query: 1638 SHSSKY--TIEASNTAG----TSSVEVTLKVYDKPSKPEGPVIMREISRES------VTI 1685
+ ++ S G +S + + KP P + E E +
Sbjct: 729 KVDLEVPKSLAGSRQIGRFACSSLYGGSSEFVTKPQLPSPIALTVEQMDEDGKKKKMFRL 788
Query: 1686 EWK-PPLD----DGGLELTKYAIEKHEPDNNRWIK-----VADVDRDVETYCIQKLNENC 1735
W+ PP D ++ Y +E N +W V ++++D T ++ L N
Sbjct: 789 RWRLPPQHRDTRDHSPKVEGYLVELRTRKNRKWRAAERQLVGNMEKDSIT--VENLLPNT 846
Query: 1736 EYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
EY FRV + E ++ S+ +KTA PS +D++++ + W P E
Sbjct: 847 EYQFRVRSVESAAIGEPSIPSD--WVKTAPGAPSETIDNLKWRSLDSQTLLVEWQPIE 902
Score = 33.5 bits (73), Expect = 1.7
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 518 PKHTPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576
P+H D + C V+G P+P + W++ ++ PS Y L++
Sbjct: 189 PRH--DADYIALPCTVQGNPKPTVAWYKNDVEVLSPSMSNVSYLLSG--GNLLVPASSTL 244
Query: 577 DAGTFTCVAKNAAGFASSTTELI 599
+F C A+N+ G S L+
Sbjct: 245 AYSSFHCTARNSLGEVRSPPILL 267
>U49830-4|AAU20850.1| 1196|Caenorhabditis elegans Neuronal igcam
protein 6, isoform d protein.
Length = 1196
Score = 61.3 bits (142), Expect = 7e-09
Identities = 79/328 (24%), Positives = 129/328 (39%), Gaps = 33/328 (10%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P F + PK G I LEC A P P W + +P S + Y
Sbjct: 355 PQIFPEDPKV-----GDSIYLECFAYASPLPQYKWSRVDGKPIP-------ARSHISNYG 402
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
VLKI V G Y VA+N G A+ + +K++ PP +++ L +V +V
Sbjct: 403 RVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRA----PPSILQGLHDRLVPTESNV 458
Query: 753 ILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGD-----THSITILKPKKVKDEGVYTLK 806
+ + ++ W K+ KP+ L ++ H++ LK D GVY
Sbjct: 459 SFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCV 518
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
A N G + +SA++TV++ PP ++R ++ T+ + +P W
Sbjct: 519 ASNDVGSSSSSALLTVKDSAP--VFPPNAMSR--KVFAAFGSTVSIPCIFEASPRFHGKW 574
Query: 867 YRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
P + ++ +G +IE V+ D+G + C A N GK +H I V
Sbjct: 575 ADAGGSKLPQKGRIRDEEGVISIEKVLHE-----DAGLFFCTAHNKLGK-AHAQVQLIVV 628
Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS 953
K + + V L C+ S
Sbjct: 629 NKPSIKTNFLDEETVNMSCEVELTCENS 656
Score = 50.4 bits (115), Expect = 1e-05
Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 749 GESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTL 805
G+S+ L +P P W + + KP+ P +S + +LK +KV D G Y
Sbjct: 365 GDSIYLECFAYASPLPQYKWSRVDGKPI---PARSHISNYG-RVLKIEKVNYGDAGKYKC 420
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NPVPSI 864
A N+ G A + + P P + + V + + ++ + S+
Sbjct: 421 VAMNAFGSAAGEVHVKLRAP-------PSILQGLHDRLVPTESNVSFECLLSNADSYSSV 473
Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVD--SEIDSGDYKCVASNSAGKSSHGARVT 922
W+++ + I P + I+ + ++ E DSG Y+CVASN G SS A +T
Sbjct: 474 EWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLT 533
Query: 923 IDVEKVTFVKH-LQKSYETEEGKTVILEC--QTSHTVSTKW 960
+ F + + + G TV + C + S KW
Sbjct: 534 VKDSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKW 574
Score = 46.4 bits (105), Expect = 2e-04
Identities = 69/280 (24%), Positives = 119/280 (42%), Gaps = 35/280 (12%)
Query: 1138 RWFK-DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE---- 1192
+W + DG I +HI + LKI + DAG+Y C N+ +A V
Sbjct: 383 KWSRVDGKPIPARSHIS----NYGRVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLR 438
Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIE---DTEKFTLISD 1247
PSI L + +N + D V W+K K ++ EK +
Sbjct: 439 APPSILQGLH-DRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLK- 496
Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVE-----FPPKIVDYEREYRIKR 1301
+ L ++ E D Y CV D S++ + V+ FPP + R+
Sbjct: 497 IDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFPPNAMS--RKVFAAF 554
Query: 1302 GSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
GS V++ ++A P+ + +W SK+ +K + I + ++I+KV + DAG++
Sbjct: 555 GSTVSIPCIFEASPRFHGKWADAGGSKLPQKGR-----IRDEEGVISIEKVLHEDAGLFF 609
Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
N G A ++ + +++KPS K N L D ++N+
Sbjct: 610 CTAHNKLGKAHAQVQLIVVNKPSI--KTNFL--DEETVNM 645
Score = 39.9 bits (89), Expect = 0.019
Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 11/137 (8%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKL---RPKHTPD----GSTVQ 528
DE++Y L + P F +S + + F KL +P+ P+ G ++
Sbjct: 310 DEDSYACSLSVYSTQSGHYGPFFRLISSTPKLVNSTFPPKLDSTQPQIFPEDPKVGDSIY 369
Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
EC P PQ W R P++ Y L I +V DAG + CVA NA
Sbjct: 370 LECFAYASPLPQYKWSRVDGKPIPARSHISNYG----RVLKIEKVNYGDAGKYKCVAMNA 425
Query: 589 AGFASSTTELIVEAPLS 605
G A+ + + AP S
Sbjct: 426 FGSAAGEVHVKLRAPPS 442
Score = 38.3 bits (85), Expect = 0.059
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 850 IKLVARVTRNPVPSITWYRNN-EIISPS-ETITQNFDGENIELVITNVDSEIDSGDYKCV 907
I L V NP P++ WY+N+ E++SPS ++ G N+ + S + + C
Sbjct: 165 IALPCTVQGNPKPTVAWYKNDVEVLSPSMSNVSYLLSGGNL---LVPASSTLAYSSFHCT 221
Query: 908 ASNSAGK 914
A NS G+
Sbjct: 222 ARNSLGE 228
Score = 37.9 bits (84), Expect = 0.078
Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
GSTV C E PR W P + D++ V + I +V EDAG F C
Sbjct: 555 GSTVSIPCIFEASPRFHGKWADAGGSKLPQKG--RIRDEEGVIS--IEKVLHEDAGLFFC 610
Query: 584 VAKNAAGFASSTTELIV 600
A N G A + +LIV
Sbjct: 611 TAHNKLGKAHAQVQLIV 627
Score = 37.5 bits (83), Expect = 0.10
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPR-PQITWFRQTA----IIKPSQDFQMYYDDDN 564
P ++ L + P S V FEC + + WF+ ++ P++ + D N
Sbjct: 441 PSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHN 500
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V L + D+G + CVA N G +SS+ L V+
Sbjct: 501 VLHLKFAD--ETDSGVYQCVASNDVGSSSSSALLTVK 535
Score = 36.7 bits (81), Expect = 0.18
Identities = 108/538 (20%), Positives = 188/538 (34%), Gaps = 43/538 (7%)
Query: 1286 FPPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
FPPK+ + + K G + L A P P +W S++ K + I +
Sbjct: 346 FPPKLDSTQPQIFPEDPKVGDSIYLECFAYASPLPQYKW---SRVDGKPIPARSHISNYG 402
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICW 1401
L I+KV DAG YK N G A E++V + PS G + L S+++
Sbjct: 403 RVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRAPPSILQGLHDRLVPTESNVSFEC 462
Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK---TNSSYRFRAYAVNE 1458
S++ ++ + + K ++ +LK S ++ A N+
Sbjct: 463 LLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASND 522
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-R 1517
V S +S +K++ P K + + + CIF P+ W
Sbjct: 523 VGSSSSSALL----TVKDSAPVFPPNAMSRK-VFAAFGSTVSIPCIFEASPRFHGKWADA 577
Query: 1518 DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577
G KL + + C A N G+ + + KP I +
Sbjct: 578 GGSKLPQKGRIRDEEGVISIEKVLHEDAGLFFCTAHNKLGKAHAQVQLIVVNKPSIKTNF 637
Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
D + + + L P W N + EK S + + LK+
Sbjct: 638 LDEETVNMSCEVELTCENSAECPEALFEWKINDRPAKEYPSLKSKVHEKKSGHKGRHLKQ 697
Query: 1638 SHSSKY--TIEASNTAG----TSSVEVTLKVYDKPSKPEGPVIMREISRES------VTI 1685
+ ++ S G +S + + KP P + E E +
Sbjct: 698 KVDLEVPKSLAGSRQIGRFACSSLYGGSSEFVTKPQLPSPIALTVEQMDEDGKKKKMFRL 757
Query: 1686 EWK-PPLD----DGGLELTKYAIEKHEPDNNRWIK-----VADVDRDVETYCIQKLNENC 1735
W+ PP D ++ Y +E N +W V ++++D T ++ L N
Sbjct: 758 RWRLPPQHRDTRDHSPKVEGYLVELRTRKNRKWRAAERQLVGNMEKDSIT--VENLLPNT 815
Query: 1736 EYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
EY FRV + E ++ S+ +KTA PS +D++++ + W P E
Sbjct: 816 EYQFRVRSVESAAIGEPSIPSD--WVKTAPGAPSETIDNLKWRSLDSQTLLVEWQPIE 871
Score = 33.5 bits (73), Expect = 1.7
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 518 PKHTPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576
P+H D + C V+G P+P + W++ ++ PS Y L++
Sbjct: 158 PRH--DADYIALPCTVQGNPKPTVAWYKNDVEVLSPSMSNVSYLLSG--GNLLVPASSTL 213
Query: 577 DAGTFTCVAKNAAGFASSTTELI 599
+F C A+N+ G S L+
Sbjct: 214 AYSSFHCTARNSLGEVRSPPILL 236
>U67954-3|AAM54178.1| 436|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform a
protein.
Length = 436
Score = 60.9 bits (141), Expect = 1e-08
Identities = 75/280 (26%), Positives = 106/280 (37%), Gaps = 28/280 (10%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDMHMYCSVLKITNVKKF 703
EG + L C V P I W E + D+ I E M SVL I V+
Sbjct: 31 EGESLTLRCE-VEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPI 89
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGE-SVILSAQVV-G 760
Y+ E E S+ V+K++ +P VI P + R GE +++++ V G
Sbjct: 90 NSANYSCALA--EPEVSVTFVIKVQV---KPLVVISPDTGVYHARVGEKNLVITCHVKEG 144
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
NP+P + W K + + G I I + KK G Y AEN G + I
Sbjct: 145 NPKPGVVWTKQAAKLPEDIKREHGGAR-IVITEVKK-HHAGKYNCLAENIAGSDRATIDI 202
Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW----YR---NNEII 873
V AE P N I V++ PVP + W Y+ N+E
Sbjct: 203 HV-------AEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKF 255
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+ Q +G + + SE GDY C SN G
Sbjct: 256 KKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG 295
Score = 60.5 bits (140), Expect = 1e-08
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 6/111 (5%)
Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLEN 1615
EV + V+ +Q KP++ IS + +VG++ LV V EG P P V+W K KL
Sbjct: 102 EVSVTFVIKVQVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPE 161
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
D I + + I I E+K+ H+ KY A N AG+ + + V +KP
Sbjct: 162 D----IKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEKP 208
Score = 47.6 bits (108), Expect = 1e-04
Identities = 40/183 (21%), Positives = 69/183 (37%), Gaps = 13/183 (7%)
Query: 1497 EDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+++ +TC + G P+P V W + KL Y C+A N
Sbjct: 133 KNLVITCHVKEGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENI 192
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE- 1614
G + + + +KP + NED + +G P P+V W NG K+
Sbjct: 193 AGSDRATIDIHVAEKP--WVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINF 250
Query: 1615 NDKEYNITTKE-------KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
ND+++ T++ S + + ++ Y SN G SV + V +P
Sbjct: 251 NDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG--SVTAVVHVSGRPG 308
Query: 1668 KPE 1670
P+
Sbjct: 309 PPQ 311
Score = 44.0 bits (99), Expect = 0.001
Identities = 50/290 (17%), Positives = 116/290 (40%), Gaps = 35/290 (12%)
Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-------QLTIDGKKQKLKIYDCDLDD 1172
+G T E+ + W K+ + + I +++++G L I + +
Sbjct: 31 EGESLTLRCEVEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPIN 90
Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
+ YSC + + + ++ +++ +++ +T Y + ++ L +T + K
Sbjct: 91 SANYSCALAEPEVSVTFVIK-------VQVKPLVVISPDTGVY-HARVGEKNLVITCHVK 142
Query: 1233 KS-----VIEDTEKFTLISDVKKR----TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+ V+ + L D+K+ ++I + + +Y C+ + + + +++
Sbjct: 143 EGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDI 202
Query: 1284 -VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KI------IKKCKHTK 1335
V P + + + +++ + + Y P P EW+ N KI KK T
Sbjct: 203 HVAEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETA 262
Query: 1336 PSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
++ S S LT+ + G Y R+ N G ++V+ +P PP
Sbjct: 263 QRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTAVVHVS--GRPGPP 310
Score = 41.1 bits (92), Expect = 0.008
Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 7/75 (9%)
Query: 531 CQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
C V EG P+P + W +Q A K +D + + A +VI EV AG + C+A+N A
Sbjct: 139 CHVKEGNPKPGVVWTKQAA--KLPEDIKREHGG---ARIVITEVKKHHAGKYNCLAENIA 193
Query: 590 GFASSTTEL-IVEAP 603
G +T ++ + E P
Sbjct: 194 GSDRATIDIHVAEKP 208
>AF456362-1|AAL60233.1| 435|Caenorhabditis elegans immunoglobulin
domain-containingprotein WRK-1A protein.
Length = 435
Score = 60.9 bits (141), Expect = 1e-08
Identities = 75/280 (26%), Positives = 106/280 (37%), Gaps = 28/280 (10%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDMHMYCSVLKITNVKKF 703
EG + L C V P I W E + D+ I E M SVL I V+
Sbjct: 30 EGESLTLRCE-VEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPI 88
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGE-SVILSAQVV-G 760
Y+ E E S+ V+K++ +P VI P + R GE +++++ V G
Sbjct: 89 NSANYSCALA--EPEVSVTFVIKVQV---KPLVVISPDTGVYHARVGEKNLVITCHVKEG 143
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
NP+P + W K + + G I I + KK G Y AEN G + I
Sbjct: 144 NPKPGVVWTKQAAKLPEDIKREHGGAR-IVITEVKK-HHAGKYNCLAENIAGSDRATIDI 201
Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW----YR---NNEII 873
V AE P N I V++ PVP + W Y+ N+E
Sbjct: 202 HV-------AEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKF 254
Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
+ Q +G + + SE GDY C SN G
Sbjct: 255 KKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG 294
Score = 60.5 bits (140), Expect = 1e-08
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 6/111 (5%)
Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLEN 1615
EV + V+ +Q KP++ IS + +VG++ LV V EG P P V+W K KL
Sbjct: 101 EVSVTFVIKVQVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPE 160
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
D I + + I I E+K+ H+ KY A N AG+ + + V +KP
Sbjct: 161 D----IKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEKP 207
Score = 47.6 bits (108), Expect = 1e-04
Identities = 40/183 (21%), Positives = 69/183 (37%), Gaps = 13/183 (7%)
Query: 1497 EDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+++ +TC + G P+P V W + KL Y C+A N
Sbjct: 132 KNLVITCHVKEGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENI 191
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE- 1614
G + + + +KP + NED + +G P P+V W NG K+
Sbjct: 192 AGSDRATIDIHVAEKP--WVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINF 249
Query: 1615 NDKEYNITTKE-------KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
ND+++ T++ S + + ++ Y SN G SV + V +P
Sbjct: 250 NDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLG--SVTAVVHVSGRPG 307
Query: 1668 KPE 1670
P+
Sbjct: 308 PPQ 310
Score = 44.0 bits (99), Expect = 0.001
Identities = 50/290 (17%), Positives = 116/290 (40%), Gaps = 35/290 (12%)
Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-------QLTIDGKKQKLKIYDCDLDD 1172
+G T E+ + W K+ + + I +++++G L I + +
Sbjct: 30 EGESLTLRCEVEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPIN 89
Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
+ YSC + + + ++ +++ +++ +T Y + ++ L +T + K
Sbjct: 90 SANYSCALAEPEVSVTFVIK-------VQVKPLVVISPDTGVY-HARVGEKNLVITCHVK 141
Query: 1233 KS-----VIEDTEKFTLISDVKKR----TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
+ V+ + L D+K+ ++I + + +Y C+ + + + +++
Sbjct: 142 EGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDI 201
Query: 1284 -VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KI------IKKCKHTK 1335
V P + + + +++ + + Y P P EW+ N KI KK T
Sbjct: 202 HVAEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETA 261
Query: 1336 PSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
++ S S LT+ + G Y R+ N G ++V+ +P PP
Sbjct: 262 QRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTAVVHVS--GRPGPP 309
Score = 41.1 bits (92), Expect = 0.008
Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 7/75 (9%)
Query: 531 CQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
C V EG P+P + W +Q A K +D + + A +VI EV AG + C+A+N A
Sbjct: 138 CHVKEGNPKPGVVWTKQAA--KLPEDIKREHGG---ARIVITEVKKHHAGKYNCLAENIA 192
Query: 590 GFASSTTEL-IVEAP 603
G +T ++ + E P
Sbjct: 193 GSDRATIDIHVAEKP 207
>U42847-4|AAF23186.1| 1073|Caenorhabditis elegans Immunoglobulin-like
cell adhesionmolecule family protein 1 protein.
Length = 1073
Score = 60.5 bits (140), Expect = 1e-08
Identities = 158/729 (21%), Positives = 280/729 (38%), Gaps = 103/729 (14%)
Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD---EGEYSC--ILRDES---CTAEVTV 1102
++ +++ K +++ E +R T V EG Y C I D+S +A TV
Sbjct: 78 KNDKLLAKKHSRFILENDSATGNYSLRITEVEKNSVEGTYHCNVIGTDDSDVQYSALATV 137
Query: 1103 VELPPE---IITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTI- 1156
V L P II+ ++ V +G+ T + G W I S
Sbjct: 138 VVLVPPGDPIISTTPSESVIEGDFMTAKCVSVGGSPQPTFTWTLPNDTIASSAIFTTQFR 197
Query: 1157 DGKKQKLKIYDCDLDDAGE-YSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVPANTDA 1214
DG + L + D G+ C+V N T + S L P + P
Sbjct: 198 DGATESLLHFRVTSSDDGKSVQCDVTNRAMLGGETKQVKSSQLNVLYKPVVFVTPTENLT 257
Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK---RTLIIR---KCTEDDQCEYTC 1268
+L+VE E +++T + + ++ I+ ++ + IR + D +C T
Sbjct: 258 HLSVE-EGELVNLTCNSASNPPAHSYEWKHIASGERYQGKIWPIRVDSSMSGDFECRSTN 316
Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND-EWIVNSKI 1327
L + T LK+ VV+ P+I + D+ +L + A P+ D +W+ +
Sbjct: 317 EL--GEGTAVLKM-VVQHIPRI-NVPESISPNEMEDIDILCEVSAVPEVIDIKWVGPN-- 370
Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC---GHADVEMNV----TILDK 1380
+ LTI + +G Y N GH+ + + TI+D
Sbjct: 371 ---------GFKQNGSRLTITSISKAQSGNYTCMATNFLTVYGHSGSQQRMGTGTTIVDV 421
Query: 1381 PSPPGKPNILE----IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
PG+ I+ +D + E+ GN + Y + + ++ T+
Sbjct: 422 KRKPGQAQIVSARQNVDVGETIKLMCQAEDAGNPSASY---TWASPSSGGIFGLEGHTEK 478
Query: 1437 QTSIQN--LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
++N L N Y +AY D+ + T VI++ +I SP + I T
Sbjct: 479 SFEVRNAQLSDNGVYSCKAYN----DLGEGKIGTVMITVIEKARISSPLATE---RIFTS 531
Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKATYENR-------------XXXXX 1537
+ L C G P P + W +DG+ +K + AT E++
Sbjct: 532 GEQGKILECEAQGYPSPVIKWLKDGRPVKQSIYASSATSESKCLPEDFCTQTVASTLTLA 591
Query: 1538 XXXXXXXXXXYKCIAFN--DHGEVETS--CVVGIQQKPVITISNEDIKQKH----KVGDE 1589
+ C+A N D + ++S +V + KPV N +K +G +
Sbjct: 592 GPLKWSDKGNFTCVADNGSDKTDKDSSSWTIVRVLHKPVFL--NRKFPEKSLAAADIGSQ 649
Query: 1590 WLVTAVIEGIPPPEVIW-YKNGNKLENDKE----YNITTK--EKTSVIRIKELKRSHSSK 1642
++ + P PE W +++ EN++ IT K E +++I+ ++ S +
Sbjct: 650 AIIRCKVSARPEPEFHWMFRDSEISENERHSFHTVGITGKPDEYEQLLQIESVQESDYGE 709
Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS--RESVTIEWKPPLDDGGLELTK 1700
Y A+N G V + L+ K S P P+ ++++S SV + W P DGG + T
Sbjct: 710 YVCRATNGNGGDHVVIELR---KTSPPALPLDLQKLSATSNSVLLGWVPQF-DGGADQT- 764
Query: 1701 YAIEKHEPD 1709
Y +E + D
Sbjct: 765 YVLETRKID 773
Score = 56.4 bits (130), Expect = 2e-07
Identities = 77/309 (24%), Positives = 125/309 (40%), Gaps = 44/309 (14%)
Query: 693 SVLKITNVKKFQEGTYTVVAVN------------REGEASLPIVLKIKTGEKEPPQVIEP 740
S L IT++ K Q G YT +A N R G + + +K K G+ Q++
Sbjct: 377 SRLTITSISKAQSGNYTCMATNFLTVYGHSGSQQRMGTGTTIVDVKRKPGQ---AQIVSA 433
Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE 800
+++ V + ++ A+ GNP + TW P +G T ++ ++ D
Sbjct: 434 RQNVDVGETIKLMCQAEDAGNPSASYTWA---SPSSGGIFGLEGHTEKSFEVRNAQLSDN 490
Query: 801 GVYTLKAENSEGIAETSAV-ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
GVY+ KA N G + V ITV E + PL R T E+G I L
Sbjct: 491 GVYSCKAYNDLGEGKIGTVMITVIE--KARISSPLATERI--FTSGEQGKI-LECEAQGY 545
Query: 860 PVPSITWYRNNEII----------SPSETITQNFDGENIELVITNVD--SEIDSGDYKCV 907
P P I W ++ + S S+ + ++F + + +T D G++ CV
Sbjct: 546 PSPVIKWLKDGRPVKQSIYASSATSESKCLPEDFCTQTVASTLTLAGPLKWSDKGNFTCV 605
Query: 908 ASNSAGKS---SHGARVTIDVEKVTFV--KHLQKSYETEE-GKTVILECQTSHTVSTK-- 959
A N + K+ S + + K F+ K +KS + G I+ C+ S +
Sbjct: 606 ADNGSDKTDKDSSSWTIVRVLHKPVFLNRKFPEKSLAAADIGSQAIIRCKVSARPEPEFH 665
Query: 960 WYHNKKEIS 968
W EIS
Sbjct: 666 WMFRDSEIS 674
Score = 54.8 bits (126), Expect = 6e-07
Identities = 84/316 (26%), Positives = 129/316 (40%), Gaps = 48/316 (15%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
Q VD G I L C+ P ++ + P +E H S ++ N +
Sbjct: 435 QNVDVGETIKLMCQAEDAGNPSASYTWAS----PSSGGIFGLEG--HTEKS-FEVRNAQL 487
Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS-MIVRQGES-VILSAQVVG 760
G Y+ A N GE + V+ I EK ++ PL + I GE IL + G
Sbjct: 488 SDNGVYSCKAYNDLGEGKIGTVM-ITVIEKA--RISSPLATERIFTSGEQGKILECEAQG 544
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHS---------------ITILKPKKVKDEGVYTL 805
P P I W K+ +PVK S + S +T+ P K D+G +T
Sbjct: 545 YPSPVIKWLKDGRPVKQSIYASSATSESKCLPEDFCTQTVASTLTLAGPLKWSDKGNFTC 604
Query: 806 KAEN-SEGIAETSAVITVEEPTEENAEPPLFINR-FQE--ITVKEKGTIKLV-ARVTRNP 860
A+N S+ + S+ T+ + P+F+NR F E + + G+ ++ +V+ P
Sbjct: 605 VADNGSDKTDKDSSSWTIVRVLHK----PVFLNRKFPEKSLAAADIGSQAIIRCKVSARP 660
Query: 861 VPSITWYRNNEIISPSET-------ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
P W + IS +E IT D L I +V E D G+Y C A+N G
Sbjct: 661 EPEFHWMFRDSEISENERHSFHTVGITGKPDEYEQLLQIESV-QESDYGEYVCRATNGNG 719
Query: 914 KSSHGARVTIDVEKVT 929
G V I++ K +
Sbjct: 720 ----GDHVVIELRKTS 731
Score = 54.0 bits (124), Expect = 1e-06
Identities = 54/217 (24%), Positives = 89/217 (41%), Gaps = 14/217 (6%)
Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
EC+ +GYP P I W + +K S +Y + + PED T T +
Sbjct: 539 ECEAQGYPSPVIKWLKDGRPVKQS----IYASSATSES----KCLPEDFCTQTVASTLTL 590
Query: 590 GFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGS 649
++ ++D+GS+ T + + F +K A D GS
Sbjct: 591 AGPLKWSDKGNFTCVADNGSDKTDKDSSSWTIVRVLHKPVF-LNRKFPEKSLAA-ADIGS 648
Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENIS---VAIESDMHMYCSVLKITNVKKFQEG 706
++ C++ A PEP+ W+F+ EI +E S V I Y +L+I +V++ G
Sbjct: 649 QAIIRCKVSARPEPEFHWMFRDSEISENERHSFHTVGITGKPDEYEQLLQIESVQESDYG 708
Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
Y A N G + I L+ KT P ++ L +
Sbjct: 709 EYVCRATNGNGGDHVVIELR-KTSPPALPLDLQKLSA 744
Score = 50.0 bits (114), Expect = 2e-05
Identities = 158/715 (22%), Positives = 266/715 (37%), Gaps = 102/715 (14%)
Query: 778 LPTKSDGDTHSITILKPKKVKDEGVY---TLKAENSEGIAETSAVITVEEPTEENAEPPL 834
L S +S+ I + +K EG Y + ++S+ A + V P +P +
Sbjct: 92 LENDSATGNYSLRITEVEKNSVEGTYHCNVIGTDDSDVQYSALATVVVLVPP---GDPII 148
Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-DGENIELVIT 893
+ + + T K V+ V +P P+ TW N+ I+ S T F DG L+
Sbjct: 149 STTPSESVIEGDFMTAKCVS-VGGSPQPTFTWTLPNDTIASSAIFTTQFRDGATESLLHF 207
Query: 894 NVDSEIDSGDYKCVASNSA-----GKSSHGARVTIDVEKVTFVKHLQK--SYETEEGKTV 946
V S D +C +N A K +++ + + V FV + EEG+ V
Sbjct: 208 RVTSSDDGKSVQCDVTNRAMLGGETKQVKSSQLNVLYKPVVFVTPTENLTHLSVEEGELV 267
Query: 947 ILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006
L C ++ Y K SG + +G+ D + T
Sbjct: 268 NLTCNSASNPPAHSYEWKHIASGERY-----QGKIWPIRVDSSMSGDFECRSTNELGEGT 322
Query: 1007 STMLVVKETIPEF--IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064
+ + +V + IP + E+++ D+ + EV E D+ W + P
Sbjct: 323 AVLKMVVQHIPRINVPESISPNEMEDIDI-LCEVSAVPEVIDIKW------VGPN----G 371
Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRD-----------ESCTAEVTVVEL-----PPE 1108
F++ G +L I + S G Y+C+ + + T+V++ +
Sbjct: 372 FKQNG--SRLTITSISKAQSGNYTCMATNFLTVYGHSGSQQRMGTGTTIVDVKRKPGQAQ 429
Query: 1109 IITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK-LKIY 1166
I++ QN V + K + E A W S F ++G +K ++
Sbjct: 430 IVSARQNVDVGETIKLMCQAEDAGNPSASYTWASPSSGGIFG------LEGHTEKSFEVR 483
Query: 1167 DCDLDDAGEYSC----EVGNSKC-TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
+ L D G YSC ++G K T ++TV E + + E I L E
Sbjct: 484 NAQLSDNGVYSCKAYNDLGEGKIGTVMITVIEKARISSPLATERIFTSGEQGKILECEAQ 543
Query: 1222 DETLDV-TWYK-----KKSVIED---TEKFTLISDVKKRTL-----IIRKCTEDDQCEYT 1267
V W K K+S+ +E L D +T+ + D+ +T
Sbjct: 544 GYPSPVIKWLKDGRPVKQSIYASSATSESKCLPEDFCTQTVASTLTLAGPLKWSDKGNFT 603
Query: 1268 CVLLDAKSTT---KLKVEVVEFPPKIVDYEREYRIKR------GSDVTLLVDYQAFPQPN 1318
CV + T +V K V R++ K GS + A P+P
Sbjct: 604 CVADNGSDKTDKDSSSWTIVRVLHKPVFLNRKFPEKSLAAADIGSQAIIRCKVSARPEPE 663
Query: 1319 DEWIV-NSKIIKKCKHTKPSI------DSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
W+ +S+I + +H+ ++ D L I+ V+ +D G Y R N G V
Sbjct: 664 FHWMFRDSEISENERHSFHTVGITGKPDEYEQLLQIESVQESDYGEYVCRATNGNGGDHV 723
Query: 1372 EMNVTILDKPSPPGKP---NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
V L K SPP P L S+S+ + W P+ G + YV+E ++ID
Sbjct: 724 ---VIELRKTSPPALPLDLQKLSATSNSVLLGW-VPQFDGGADQT-YVLETRKID 773
>U50067-4|AAA93439.3| 1144|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform a protein.
Length = 1144
Score = 60.1 bits (139), Expect = 2e-08
Identities = 77/331 (23%), Positives = 134/331 (40%), Gaps = 37/331 (11%)
Query: 640 PKAQYVDEGSDILLE-------CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P QYV++ S I L+ C P P W G EI D + A Y
Sbjct: 69 PTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD---AAGFRFESYG 125
Query: 693 SVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
L + NV + + G Y A ++ + + +V+ E P + P + +GE
Sbjct: 126 KTL-VFNVTQDKAGKYDCRFATQQDIDRTFNVVV-----EAAPYWPLGPPPNTNTSEGEK 179
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKK----VKDEGVYT 804
VI G P P +T+ KN +++ K D + +TI KK D VY
Sbjct: 180 VIFDCTTYGKPTPKVTFYKNGVEIES--QKDDRYLIEGTRLTIFDVKKGTYGKGDNAVYQ 237
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863
K+EN G T+ + + +P L I+ +E G + L + +P +
Sbjct: 238 CKSENKHGWLWTNFYLNLLA-----FKPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAA 292
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ W +IS S+ D + ++ + + + G+Y+C+ +N G+++ +T+
Sbjct: 293 VKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQAT--GLITL 348
Query: 924 DVEKVTFVKHLQKSYETE-EGKTVILECQTS 953
V K T V+ + E G+ + L C +
Sbjct: 349 KVRKPTIVQPFPRVEEVRMAGEEMRLACDAT 379
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 6/123 (4%)
Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+L C F G P PK W+ +G+++ A +E+ Y C F
Sbjct: 88 KLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVTQDKAGKYDC-RFAT 146
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+++ + V ++ P + G++ + G P P+V +YKNG ++E+
Sbjct: 147 QQDIDRTFNVVVEAAPYWPLGPPP-NTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIES 205
Query: 1616 DKE 1618
K+
Sbjct: 206 QKD 208
Score = 37.5 bits (83), Expect = 0.10
Identities = 57/286 (19%), Positives = 99/286 (34%), Gaps = 13/286 (4%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++E P P EG ++ +C P P + + G EI ++ IE
Sbjct: 157 VVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGT 216
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-V 746
V K T K Y + N+ G L + +P +I+P K +
Sbjct: 217 RLTIFDVKKGT-YGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEA 273
Query: 747 RQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
G+ V L + +P + W K +D + +EG Y
Sbjct: 274 VAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYEC 333
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864
N G A + V +PT P R +E+ + E+ + A
Sbjct: 334 IGTNKYGQATGLITLKVRKPTIVQPFP-----RVEEVRMAGEEMRLACDATADNQLEVKY 388
Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVAS 909
W + + + + ++ ++ LVI+N ++ D+ YKCV S
Sbjct: 389 EWLVDGKSLPEDRISSGHYKIDDDHSLVISN-PTQDDTAKYKCVVS 433
Score = 35.5 bits (78), Expect = 0.42
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 22/186 (11%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SE 1792
+Y+FRVIA+N VG S A ++ +T P E++ + W P E
Sbjct: 538 KYVFRVIARNSVGDSAARLAKD-QCETPAKQPDKNPDEVAAKGTSPENIIVQWKPMSREE 596
Query: 1793 KNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARI-------QKLSINTTYQFRIYAR 1842
NG K K E ++ WK R+ + + Y+ ++ A
Sbjct: 597 WNGADFHYVVKYRPKDEDQRVGDWKEVAVEDPFADRVTVNLDDEKDVKPFQPYEVQVQAV 656
Query: 1843 NEIGTS--LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNGGSPIT 1898
N G + +P T + + G P S P V E + +VTL W +P++ G+ T
Sbjct: 657 NSEGRTNVVPETVEGRTGEG---VPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGN-FT 712
Query: 1899 NYIIEF 1904
Y I +
Sbjct: 713 GYKITY 718
Score = 35.5 bits (78), Expect = 0.42
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPS 1382
N K+++K K ID+ S + I +EN + LR + G D + T L + +
Sbjct: 856 NGKLVEKSCPRK-QIDADSKEIRITGLENETPYRFILRAHTSAGEGDPNSSDATTLPETT 914
Query: 1383 P----PGKPNILE--IDSSSINICWDEPENTGNSTIIY---YVVEYQEIDTTEWISVKNI 1433
PG P+++E I N+ + + S Y V+Y+ D EW +VK
Sbjct: 915 AAGVDPGVPSLVENAIGDKYFNVSFRPAKYDDESRAPVGNTYEVQYKPQDADEWETVKPA 974
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
T + L + Y R A+ +VD + ETT+
Sbjct: 975 DDGLTVHVDGLSPGTKYDVRVAAL-QVD-PEGGETTK 1009
Score = 33.5 bits (73), Expect = 1.7
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P N T E + C G P PKVT+Y++G ++++ K
Sbjct: 168 PPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQK 207
Score = 31.5 bits (68), Expect = 6.8
Identities = 15/74 (20%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE--VFPED 577
+T +G V F+C G P P++T+++ I+ +D + + + +++ D
Sbjct: 173 NTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFDVKKGTYGKGD 232
Query: 578 AGTFTCVAKNAAGF 591
+ C ++N G+
Sbjct: 233 NAVYQCKSENKHGW 246
>U50067-3|AAZ32801.1| 1147|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform d protein.
Length = 1147
Score = 60.1 bits (139), Expect = 2e-08
Identities = 77/331 (23%), Positives = 134/331 (40%), Gaps = 37/331 (11%)
Query: 640 PKAQYVDEGSDILLE-------CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P QYV++ S I L+ C P P W G EI D + A Y
Sbjct: 69 PTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD---AAGFRFESYG 125
Query: 693 SVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
L + NV + + G Y A ++ + + +V+ E P + P + +GE
Sbjct: 126 KTL-VFNVTQDKAGKYDCRFATQQDIDRTFNVVV-----EAAPYWPLGPPPNTNTSEGEK 179
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKK----VKDEGVYT 804
VI G P P +T+ KN +++ K D + +TI KK D VY
Sbjct: 180 VIFDCTTYGKPTPKVTFYKNGVEIES--QKDDRYLIEGTRLTIFDVKKGTYGKGDNAVYQ 237
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863
K+EN G T+ + + +P L I+ +E G + L + +P +
Sbjct: 238 CKSENKHGWLWTNFYLNLLA-----FKPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAA 292
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ W +IS S+ D + ++ + + + G+Y+C+ +N G+++ +T+
Sbjct: 293 VKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQAT--GLITL 348
Query: 924 DVEKVTFVKHLQKSYETE-EGKTVILECQTS 953
V K T V+ + E G+ + L C +
Sbjct: 349 KVRKPTIVQPFPRVEEVRMAGEEMRLACDAT 379
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 6/123 (4%)
Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+L C F G P PK W+ +G+++ A +E+ Y C F
Sbjct: 88 KLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVTQDKAGKYDC-RFAT 146
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+++ + V ++ P + G++ + G P P+V +YKNG ++E+
Sbjct: 147 QQDIDRTFNVVVEAAPYWPLGPPP-NTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIES 205
Query: 1616 DKE 1618
K+
Sbjct: 206 QKD 208
Score = 37.5 bits (83), Expect = 0.10
Identities = 57/286 (19%), Positives = 99/286 (34%), Gaps = 13/286 (4%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++E P P EG ++ +C P P + + G EI ++ IE
Sbjct: 157 VVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGT 216
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-V 746
V K T K Y + N+ G L + +P +I+P K +
Sbjct: 217 RLTIFDVKKGT-YGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEA 273
Query: 747 RQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
G+ V L + +P + W K +D + +EG Y
Sbjct: 274 VAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYEC 333
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864
N G A + V +PT P R +E+ + E+ + A
Sbjct: 334 IGTNKYGQATGLITLKVRKPTIVQPFP-----RVEEVRMAGEEMRLACDATADNQLEVKY 388
Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVAS 909
W + + + + ++ ++ LVI+N ++ D+ YKCV S
Sbjct: 389 EWLVDGKSLPEDRISSGHYKIDDDHSLVISN-PTQDDTAKYKCVVS 433
Score = 35.5 bits (78), Expect = 0.42
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 22/186 (11%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SE 1792
+Y+FRVIA+N VG S A ++ +T P E++ + W P E
Sbjct: 538 KYVFRVIARNSVGDSAARLAKD-QCETPAKQPDKNPDEVAAKGTSPENIIVQWKPMSREE 596
Query: 1793 KNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARI-------QKLSINTTYQFRIYAR 1842
NG K K E ++ WK R+ + + Y+ ++ A
Sbjct: 597 WNGADFHYVVKYRPKDEDQRVGDWKEVAVEDPFADRVTVNLDDEKDVKPFQPYEVQVQAV 656
Query: 1843 NEIGTS--LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNGGSPIT 1898
N G + +P T + + G P S P V E + +VTL W +P++ G+ T
Sbjct: 657 NSEGRTNVVPETVEGRTGEG---VPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGN-FT 712
Query: 1899 NYIIEF 1904
Y I +
Sbjct: 713 GYKITY 718
Score = 35.5 bits (78), Expect = 0.42
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPS 1382
N K+++K K ID+ S + I +EN + LR + G D + T L + +
Sbjct: 856 NGKLVEKSCPRK-QIDADSKEIRITGLENETPYRFILRAHTSAGEGDPNSSDATTLPETT 914
Query: 1383 P----PGKPNILE--IDSSSINICWDEPENTGNSTIIY---YVVEYQEIDTTEWISVKNI 1433
PG P+++E I N+ + + S Y V+Y+ D EW +VK
Sbjct: 915 AAGVDPGVPSLVENAIGDKYFNVSFRPAKYDDESRAPVGNTYEVQYKPQDADEWETVKPA 974
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
T + L + Y R A+ +VD + ETT+
Sbjct: 975 DDGLTVHVDGLSPGTKYDVRVAAL-QVD-PEGGETTK 1009
Score = 33.5 bits (73), Expect = 1.7
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P N T E + C G P PKVT+Y++G ++++ K
Sbjct: 168 PPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQK 207
Score = 31.5 bits (68), Expect = 6.8
Identities = 15/74 (20%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE--VFPED 577
+T +G V F+C G P P++T+++ I+ +D + + + +++ D
Sbjct: 173 NTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFDVKKGTYGKGD 232
Query: 578 AGTFTCVAKNAAGF 591
+ C ++N G+
Sbjct: 233 NAVYQCKSENKHGW 246
>U50067-2|AAY86218.1| 1328|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform b protein.
Length = 1328
Score = 60.1 bits (139), Expect = 2e-08
Identities = 77/331 (23%), Positives = 134/331 (40%), Gaps = 37/331 (11%)
Query: 640 PKAQYVDEGSDILLE-------CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P QYV++ S I L+ C P P W G EI D + A Y
Sbjct: 253 PTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD---AAGFRFESYG 309
Query: 693 SVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
L + NV + + G Y A ++ + + +V+ E P + P + +GE
Sbjct: 310 KTL-VFNVTQDKAGKYDCRFATQQDIDRTFNVVV-----EAAPYWPLGPPPNTNTSEGEK 363
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKK----VKDEGVYT 804
VI G P P +T+ KN +++ K D + +TI KK D VY
Sbjct: 364 VIFDCTTYGKPTPKVTFYKNGVEIES--QKDDRYLIEGTRLTIFDVKKGTYGKGDNAVYQ 421
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863
K+EN G T+ + + +P L I+ +E G + L + +P +
Sbjct: 422 CKSENKHGWLWTNFYLNLLA-----FKPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAA 476
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ W +IS S+ D + ++ + + + G+Y+C+ +N G+++ +T+
Sbjct: 477 VKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQAT--GLITL 532
Query: 924 DVEKVTFVKHLQKSYETE-EGKTVILECQTS 953
V K T V+ + E G+ + L C +
Sbjct: 533 KVRKPTIVQPFPRVEEVRMAGEEMRLACDAT 563
Score = 55.2 bits (127), Expect = 5e-07
Identities = 62/324 (19%), Positives = 127/324 (39%), Gaps = 24/324 (7%)
Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
P+P+ W + K + + SL +++ +DAG+Y+ EN+ G A V+
Sbjct: 73 PRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEAENSNGTA-VDR 131
Query: 1374 NVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
V + + + +P ++ ++ P + +Y+++ +E E IS
Sbjct: 132 PVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGKEPGHFETISS 191
Query: 1431 KNITKTQTSIQ-----NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS---- 1481
+I+ + N S R+ +++ D ++ I K +S
Sbjct: 192 SHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQITNNKRRSLQQM 251
Query: 1482 PTVEKPLKN---ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXX 1534
P E+ + I + N+ +L C F G P PK W+ +G+++ A +E+
Sbjct: 252 PPTEQYVNQSSPIALQGNQH-KLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGK 310
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
Y C F +++ + V ++ P + G++ +
Sbjct: 311 TLVFNVTQDKAGKYDC-RFATQQDIDRTFNVVVEAAPYWPLGPPP-NTNTSEGEKVIFDC 368
Query: 1595 VIEGIPPPEVIWYKNGNKLENDKE 1618
G P P+V +YKNG ++E+ K+
Sbjct: 369 TTYGKPTPKVTFYKNGVEIESQKD 392
Score = 38.3 bits (85), Expect = 0.059
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 1/75 (1%)
Query: 519 KHTPDGSTVQ-FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
K+TP Q C G PRP W + PS + +LV + D
Sbjct: 54 KNTPGNLLEQTIHCYANGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESD 113
Query: 578 AGTFTCVAKNAAGFA 592
AG + C A+N+ G A
Sbjct: 114 AGLYQCEAENSNGTA 128
Score = 37.5 bits (83), Expect = 0.10
Identities = 57/286 (19%), Positives = 99/286 (34%), Gaps = 13/286 (4%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++E P P EG ++ +C P P + + G EI ++ IE
Sbjct: 341 VVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGT 400
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-V 746
V K T K Y + N+ G L + +P +I+P K +
Sbjct: 401 RLTIFDVKKGT-YGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEA 457
Query: 747 RQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
G+ V L + +P + W K +D + +EG Y
Sbjct: 458 VAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYEC 517
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864
N G A + V +PT P R +E+ + E+ + A
Sbjct: 518 IGTNKYGQATGLITLKVRKPTIVQPFP-----RVEEVRMAGEEMRLACDATADNQLEVKY 572
Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVAS 909
W + + + + ++ ++ LVI+N ++ D+ YKCV S
Sbjct: 573 EWLVDGKSLPEDRISSGHYKIDDDHSLVISN-PTQDDTAKYKCVVS 617
Score = 35.5 bits (78), Expect = 0.42
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 16/95 (16%)
Query: 859 NPVPSITWYRNNEIISPS---ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
NP PS W ++ + PS E + Q GE LV + +D E D+G Y+C A NS G +
Sbjct: 72 NPRPSYRWKKDGKTFLPSMFPEKVVQK-PGEG-SLVFSRLD-ESDAGLYQCEAENSNGTA 128
Query: 916 -SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
RV + T+++H ++T E + V++E
Sbjct: 129 VDRPVRV-----QETWIRH----FKTAEPEVVVVE 154
Score = 35.5 bits (78), Expect = 0.42
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 22/186 (11%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SE 1792
+Y+FRVIA+N VG S A ++ +T P E++ + W P E
Sbjct: 722 KYVFRVIARNSVGDSAARLAKD-QCETPAKQPDKNPDEVAAKGTSPENIIVQWKPMSREE 780
Query: 1793 KNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARI-------QKLSINTTYQFRIYAR 1842
NG K K E ++ WK R+ + + Y+ ++ A
Sbjct: 781 WNGADFHYVVKYRPKDEDQRVGDWKEVAVEDPFADRVTVNLDDEKDVKPFQPYEVQVQAV 840
Query: 1843 NEIGTS--LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNGGSPIT 1898
N G + +P T + + G P S P V E + +VTL W +P++ G+ T
Sbjct: 841 NSEGRTNVVPETVEGRTGEG---VPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGN-FT 896
Query: 1899 NYIIEF 1904
Y I +
Sbjct: 897 GYKITY 902
Score = 35.5 bits (78), Expect = 0.42
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPS 1382
N K+++K K ID+ S + I +EN + LR + G D + T L + +
Sbjct: 1040 NGKLVEKSCPRK-QIDADSKEIRITGLENETPYRFILRAHTSAGEGDPNSSDATTLPETT 1098
Query: 1383 P----PGKPNILE--IDSSSINICWDEPENTGNSTIIY---YVVEYQEIDTTEWISVKNI 1433
PG P+++E I N+ + + S Y V+Y+ D EW +VK
Sbjct: 1099 AAGVDPGVPSLVENAIGDKYFNVSFRPAKYDDESRAPVGNTYEVQYKPQDADEWETVKPA 1158
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
T + L + Y R A+ +VD + ETT+
Sbjct: 1159 DDGLTVHVDGLSPGTKYDVRVAAL-QVD-PEGGETTK 1193
Score = 34.7 bits (76), Expect = 0.73
Identities = 114/567 (20%), Positives = 187/567 (32%), Gaps = 47/567 (8%)
Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYD-CDLDDAGEYSCEVGNSKCTAI---LTVEE 1193
RW KDG S + + + ++ D DAG Y CE NS TA+ + V+E
Sbjct: 78 RWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEAENSNGTAVDRPVRVQE 137
Query: 1194 PSI-NFTLRLPEFILVPANTDAYLTVEIP--DETLDVTW--YKKKSVIEDTEKFTLISDV 1248
I +F PE ++V P + V W K+ +T + IS
Sbjct: 138 TWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGKEPGHFETISSSHISSN 197
Query: 1249 KKRTLIIRKCTEDD---QCEYTCV-----LLDAKSTTKLKVEVV--------EFPPKIVD 1292
++ TL E D YTC L D K + +++ + PP
Sbjct: 198 EQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQITNNKRRSLQQMPPTEQY 257
Query: 1293 YEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
+ I +G+ L + +P P W N + I + + V
Sbjct: 258 VNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVT 317
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKP----SPPGKPNILEIDSSSINICWDEPENT 1407
AG Y R D NV + P PP N E I C + T
Sbjct: 318 QDKAGKYDCRFATQ-QDIDRTFNVVVEAAPYWPLGPPPNTNTSE-GEKVIFDCTTYGKPT 375
Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE- 1466
T VE + ++ I T+ +I ++K +Y AV + +
Sbjct: 376 PKVTFYKNGVEIESQKDDRYL----IEGTRLTIFDVK-KGTYGKGDNAVYQCKSENKHGW 430
Query: 1467 -TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR---DGKKL 1522
T +Y + K Q ++ + + + + L C F P V W G K
Sbjct: 431 LWTNFYLNLLAFKPQL-LIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKG 489
Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
A Y+CI N +G+ T + +KP I +++
Sbjct: 490 NQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQA-TGLITLKVRKPTIVQPFPRVEE 548
Query: 1583 KHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKELKRSH 1639
G+E + A + + W +G L D+ + K + + I +
Sbjct: 549 VRMAGEEMRLACDATADNQLEVKYEWLVDGKSLPEDRISSGHYKIDDDHSLVISNPTQDD 608
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++KY S E+ ++ D P
Sbjct: 609 TAKYKCVVSTKLDQVEKEIKIQFKDVP 635
Score = 31.5 bits (68), Expect = 6.8
Identities = 15/74 (20%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE--VFPED 577
+T +G V F+C G P P++T+++ I+ +D + + + +++ D
Sbjct: 357 NTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFDVKKGTYGKGD 416
Query: 578 AGTFTCVAKNAAGF 591
+ C ++N G+
Sbjct: 417 NAVYQCKSENKHGW 430
>U50067-1|AAZ32800.1| 1331|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform c protein.
Length = 1331
Score = 60.1 bits (139), Expect = 2e-08
Identities = 77/331 (23%), Positives = 134/331 (40%), Gaps = 37/331 (11%)
Query: 640 PKAQYVDEGSDILLE-------CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P QYV++ S I L+ C P P W G EI D + A Y
Sbjct: 253 PTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD---AAGFRFESYG 309
Query: 693 SVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
L + NV + + G Y A ++ + + +V+ E P + P + +GE
Sbjct: 310 KTL-VFNVTQDKAGKYDCRFATQQDIDRTFNVVV-----EAAPYWPLGPPPNTNTSEGEK 363
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKK----VKDEGVYT 804
VI G P P +T+ KN +++ K D + +TI KK D VY
Sbjct: 364 VIFDCTTYGKPTPKVTFYKNGVEIES--QKDDRYLIEGTRLTIFDVKKGTYGKGDNAVYQ 421
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863
K+EN G T+ + + +P L I+ +E G + L + +P +
Sbjct: 422 CKSENKHGWLWTNFYLNLLA-----FKPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAA 476
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ W +IS S+ D + ++ + + + G+Y+C+ +N G+++ +T+
Sbjct: 477 VKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQAT--GLITL 532
Query: 924 DVEKVTFVKHLQKSYETE-EGKTVILECQTS 953
V K T V+ + E G+ + L C +
Sbjct: 533 KVRKPTIVQPFPRVEEVRMAGEEMRLACDAT 563
Score = 55.2 bits (127), Expect = 5e-07
Identities = 62/324 (19%), Positives = 127/324 (39%), Gaps = 24/324 (7%)
Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
P+P+ W + K + + SL +++ +DAG+Y+ EN+ G A V+
Sbjct: 73 PRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEAENSNGTA-VDR 131
Query: 1374 NVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
V + + + +P ++ ++ P + +Y+++ +E E IS
Sbjct: 132 PVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGKEPGHFETISS 191
Query: 1431 KNITKTQTSIQ-----NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS---- 1481
+I+ + N S R+ +++ D ++ I K +S
Sbjct: 192 SHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQITNNKRRSLQQM 251
Query: 1482 PTVEKPLKN---ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXX 1534
P E+ + I + N+ +L C F G P PK W+ +G+++ A +E+
Sbjct: 252 PPTEQYVNQSSPIALQGNQH-KLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGK 310
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
Y C F +++ + V ++ P + G++ +
Sbjct: 311 TLVFNVTQDKAGKYDC-RFATQQDIDRTFNVVVEAAPYWPLGPPP-NTNTSEGEKVIFDC 368
Query: 1595 VIEGIPPPEVIWYKNGNKLENDKE 1618
G P P+V +YKNG ++E+ K+
Sbjct: 369 TTYGKPTPKVTFYKNGVEIESQKD 392
Score = 38.3 bits (85), Expect = 0.059
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 1/75 (1%)
Query: 519 KHTPDGSTVQ-FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
K+TP Q C G PRP W + PS + +LV + D
Sbjct: 54 KNTPGNLLEQTIHCYANGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESD 113
Query: 578 AGTFTCVAKNAAGFA 592
AG + C A+N+ G A
Sbjct: 114 AGLYQCEAENSNGTA 128
Score = 37.5 bits (83), Expect = 0.10
Identities = 57/286 (19%), Positives = 99/286 (34%), Gaps = 13/286 (4%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++E P P EG ++ +C P P + + G EI ++ IE
Sbjct: 341 VVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGT 400
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-V 746
V K T K Y + N+ G L + +P +I+P K +
Sbjct: 401 RLTIFDVKKGT-YGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEA 457
Query: 747 RQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
G+ V L + +P + W K +D + +EG Y
Sbjct: 458 VAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYEC 517
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864
N G A + V +PT P R +E+ + E+ + A
Sbjct: 518 IGTNKYGQATGLITLKVRKPTIVQPFP-----RVEEVRMAGEEMRLACDATADNQLEVKY 572
Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVAS 909
W + + + + ++ ++ LVI+N ++ D+ YKCV S
Sbjct: 573 EWLVDGKSLPEDRISSGHYKIDDDHSLVISN-PTQDDTAKYKCVVS 617
Score = 35.5 bits (78), Expect = 0.42
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 16/95 (16%)
Query: 859 NPVPSITWYRNNEIISPS---ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
NP PS W ++ + PS E + Q GE LV + +D E D+G Y+C A NS G +
Sbjct: 72 NPRPSYRWKKDGKTFLPSMFPEKVVQK-PGEG-SLVFSRLD-ESDAGLYQCEAENSNGTA 128
Query: 916 -SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
RV + T+++H ++T E + V++E
Sbjct: 129 VDRPVRV-----QETWIRH----FKTAEPEVVVVE 154
Score = 35.5 bits (78), Expect = 0.42
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 22/186 (11%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SE 1792
+Y+FRVIA+N VG S A ++ +T P E++ + W P E
Sbjct: 722 KYVFRVIARNSVGDSAARLAKD-QCETPAKQPDKNPDEVAAKGTSPENIIVQWKPMSREE 780
Query: 1793 KNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARI-------QKLSINTTYQFRIYAR 1842
NG K K E ++ WK R+ + + Y+ ++ A
Sbjct: 781 WNGADFHYVVKYRPKDEDQRVGDWKEVAVEDPFADRVTVNLDDEKDVKPFQPYEVQVQAV 840
Query: 1843 NEIGTS--LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNGGSPIT 1898
N G + +P T + + G P S P V E + +VTL W +P++ G+ T
Sbjct: 841 NSEGRTNVVPETVEGRTGEG---VPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGN-FT 896
Query: 1899 NYIIEF 1904
Y I +
Sbjct: 897 GYKITY 902
Score = 35.5 bits (78), Expect = 0.42
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPS 1382
N K+++K K ID+ S + I +EN + LR + G D + T L + +
Sbjct: 1040 NGKLVEKSCPRK-QIDADSKEIRITGLENETPYRFILRAHTSAGEGDPNSSDATTLPETT 1098
Query: 1383 P----PGKPNILE--IDSSSINICWDEPENTGNSTIIY---YVVEYQEIDTTEWISVKNI 1433
PG P+++E I N+ + + S Y V+Y+ D EW +VK
Sbjct: 1099 AAGVDPGVPSLVENAIGDKYFNVSFRPAKYDDESRAPVGNTYEVQYKPQDADEWETVKPA 1158
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
T + L + Y R A+ +VD + ETT+
Sbjct: 1159 DDGLTVHVDGLSPGTKYDVRVAAL-QVD-PEGGETTK 1193
Score = 34.7 bits (76), Expect = 0.73
Identities = 114/567 (20%), Positives = 187/567 (32%), Gaps = 47/567 (8%)
Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYD-CDLDDAGEYSCEVGNSKCTAI---LTVEE 1193
RW KDG S + + + ++ D DAG Y CE NS TA+ + V+E
Sbjct: 78 RWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEAENSNGTAVDRPVRVQE 137
Query: 1194 PSI-NFTLRLPEFILVPANTDAYLTVEIP--DETLDVTW--YKKKSVIEDTEKFTLISDV 1248
I +F PE ++V P + V W K+ +T + IS
Sbjct: 138 TWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGKEPGHFETISSSHISSN 197
Query: 1249 KKRTLIIRKCTEDD---QCEYTCV-----LLDAKSTTKLKVEVV--------EFPPKIVD 1292
++ TL E D YTC L D K + +++ + PP
Sbjct: 198 EQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQITNNKRRSLQQMPPTEQY 257
Query: 1293 YEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
+ I +G+ L + +P P W N + I + + V
Sbjct: 258 VNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVT 317
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKP----SPPGKPNILEIDSSSINICWDEPENT 1407
AG Y R D NV + P PP N E I C + T
Sbjct: 318 QDKAGKYDCRFATQ-QDIDRTFNVVVEAAPYWPLGPPPNTNTSE-GEKVIFDCTTYGKPT 375
Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE- 1466
T VE + ++ I T+ +I ++K +Y AV + +
Sbjct: 376 PKVTFYKNGVEIESQKDDRYL----IEGTRLTIFDVK-KGTYGKGDNAVYQCKSENKHGW 430
Query: 1467 -TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR---DGKKL 1522
T +Y + K Q ++ + + + + L C F P V W G K
Sbjct: 431 LWTNFYLNLLAFKPQL-LIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKG 489
Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
A Y+CI N +G+ T + +KP I +++
Sbjct: 490 NQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQA-TGLITLKVRKPTIVQPFPRVEE 548
Query: 1583 KHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKELKRSH 1639
G+E + A + + W +G L D+ + K + + I +
Sbjct: 549 VRMAGEEMRLACDATADNQLEVKYEWLVDGKSLPEDRISSGHYKIDDDHSLVISNPTQDD 608
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++KY S E+ ++ D P
Sbjct: 609 TAKYKCVVSTKLDQVEKEIKIQFKDVP 635
Score = 31.5 bits (68), Expect = 6.8
Identities = 15/74 (20%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE--VFPED 577
+T +G V F+C G P P++T+++ I+ +D + + + +++ D
Sbjct: 357 NTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFDVKKGTYGKGD 416
Query: 578 AGTFTCVAKNAAGF 591
+ C ++N G+
Sbjct: 417 NAVYQCKSENKHGW 430
>AB206670-1|BAD97389.1| 1147|Caenorhabditis elegans SAX-7 SHORTFORM
protein.
Length = 1147
Score = 60.1 bits (139), Expect = 2e-08
Identities = 77/331 (23%), Positives = 134/331 (40%), Gaps = 37/331 (11%)
Query: 640 PKAQYVDEGSDILLE-------CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P QYV++ S I L+ C P P W G EI D + A Y
Sbjct: 69 PTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD---AAGFRFESYG 125
Query: 693 SVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
L + NV + + G Y A ++ + + +V+ E P + P + +GE
Sbjct: 126 KTL-VFNVTQDKAGKYDCRFATQQDIDRTFNVVV-----EAAPYWPLGPPPNTNTSEGEK 179
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKK----VKDEGVYT 804
VI G P P +T+ KN +++ K D + +TI KK D VY
Sbjct: 180 VIFDCTTYGKPTPKVTFYKNGVEIES--QKDDRYLIEGTRLTIFDVKKGTYGKGDNAVYQ 237
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863
K+EN G T+ + + +P L I+ +E G + L + +P +
Sbjct: 238 CKSENKHGWLWTNFYLNLLA-----FKPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAA 292
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ W +IS S+ D + ++ + + + G+Y+C+ +N G+++ +T+
Sbjct: 293 VKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQAT--GLITL 348
Query: 924 DVEKVTFVKHLQKSYETE-EGKTVILECQTS 953
V K T V+ + E G+ + L C +
Sbjct: 349 KVRKPTIVQPFPRVEEVRMAGEEMRLACDAT 379
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 6/123 (4%)
Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
+L C F G P PK W+ +G+++ A +E+ Y C F
Sbjct: 88 KLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVTQDKAGKYDC-RFAT 146
Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
+++ + V ++ P + G++ + G P P+V +YKNG ++E+
Sbjct: 147 QQDIDRTFNVVVEAAPYWPLGPPP-NTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIES 205
Query: 1616 DKE 1618
K+
Sbjct: 206 QKD 208
Score = 37.5 bits (83), Expect = 0.10
Identities = 57/286 (19%), Positives = 99/286 (34%), Gaps = 13/286 (4%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++E P P EG ++ +C P P + + G EI ++ IE
Sbjct: 157 VVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGT 216
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-V 746
V K T K Y + N+ G L + +P +I+P K +
Sbjct: 217 RLTIFDVKKGT-YGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEA 273
Query: 747 RQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
G+ V L + +P + W K +D + +EG Y
Sbjct: 274 VAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYEC 333
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864
N G A + V +PT P R +E+ + E+ + A
Sbjct: 334 IGTNKYGQATGLITLKVRKPTIVQPFP-----RVEEVRMAGEEMRLACDATADNQLEVKY 388
Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVAS 909
W + + + + ++ ++ LVI+N ++ D+ YKCV S
Sbjct: 389 EWLVDGKSLPEDRISSGHYKIDDDHSLVISN-PTQDDTAKYKCVVS 433
Score = 35.5 bits (78), Expect = 0.42
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 22/186 (11%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SE 1792
+Y+FRVIA+N VG S A ++ +T P E++ + W P E
Sbjct: 538 KYVFRVIARNSVGDSAARLAKD-QCETPAKQPDKNPDEVAAKGTSPENIIVQWKPMSREE 596
Query: 1793 KNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARI-------QKLSINTTYQFRIYAR 1842
NG K K E ++ WK R+ + + Y+ ++ A
Sbjct: 597 WNGADFHYVVKYRPKDEDQRVGDWKEVAVEDPFADRVTVNLDDEKDVKPFQPYEVQVQAV 656
Query: 1843 NEIGTS--LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNGGSPIT 1898
N G + +P T + + G P S P V E + +VTL W +P++ G+ T
Sbjct: 657 NSEGRTNVVPETVEGRTGEG---VPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGN-FT 712
Query: 1899 NYIIEF 1904
Y I +
Sbjct: 713 GYKITY 718
Score = 35.5 bits (78), Expect = 0.42
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPS 1382
N K+++K K ID+ S + I +EN + LR + G D + T L + +
Sbjct: 856 NGKLVEKSCPRK-QIDADSKEIRITGLENETPYRFILRAHTSAGEGDPNSSDATTLPETT 914
Query: 1383 P----PGKPNILE--IDSSSINICWDEPENTGNSTIIY---YVVEYQEIDTTEWISVKNI 1433
PG P+++E I N+ + + S Y V+Y+ D EW +VK
Sbjct: 915 AAGVDPGVPSLVENAIGDKYFNVSFRPAKYDDESRAPVGNTYEVQYKPQDADEWETVKPA 974
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
T + L + Y R A+ +VD + ETT+
Sbjct: 975 DDGLTVHVDGLSPGTKYDVRVAAL-QVD-PEGGETTK 1009
Score = 33.5 bits (73), Expect = 1.7
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P N T E + C G P PKVT+Y++G ++++ K
Sbjct: 168 PPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQK 207
Score = 31.5 bits (68), Expect = 6.8
Identities = 15/74 (20%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE--VFPED 577
+T +G V F+C G P P++T+++ I+ +D + + + +++ D
Sbjct: 173 NTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFDVKKGTYGKGD 232
Query: 578 AGTFTCVAKNAAGF 591
+ C ++N G+
Sbjct: 233 NAVYQCKSENKHGW 246
>AB206669-1|BAD97388.1| 1331|Caenorhabditis elegans SAX-7 LONGFORM
protein.
Length = 1331
Score = 60.1 bits (139), Expect = 2e-08
Identities = 77/331 (23%), Positives = 134/331 (40%), Gaps = 37/331 (11%)
Query: 640 PKAQYVDEGSDILLE-------CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
P QYV++ S I L+ C P P W G EI D + A Y
Sbjct: 253 PTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD---AAGFRFESYG 309
Query: 693 SVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
L + NV + + G Y A ++ + + +V+ E P + P + +GE
Sbjct: 310 KTL-VFNVTQDKAGKYDCRFATQQDIDRTFNVVV-----EAAPYWPLGPPPNTNTSEGEK 363
Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKK----VKDEGVYT 804
VI G P P +T+ KN +++ K D + +TI KK D VY
Sbjct: 364 VIFDCTTYGKPTPKVTFYKNGVEIES--QKDDRYLIEGTRLTIFDVKKGTYGKGDNAVYQ 421
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863
K+EN G T+ + + +P L I+ +E G + L + +P +
Sbjct: 422 CKSENKHGWLWTNFYLNLLA-----FKPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAA 476
Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ W +IS S+ D + ++ + + + G+Y+C+ +N G+++ +T+
Sbjct: 477 VKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQAT--GLITL 532
Query: 924 DVEKVTFVKHLQKSYETE-EGKTVILECQTS 953
V K T V+ + E G+ + L C +
Sbjct: 533 KVRKPTIVQPFPRVEEVRMAGEEMRLACDAT 563
Score = 55.2 bits (127), Expect = 5e-07
Identities = 62/324 (19%), Positives = 127/324 (39%), Gaps = 24/324 (7%)
Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
P+P+ W + K + + SL +++ +DAG+Y+ EN+ G A V+
Sbjct: 73 PRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEAENSNGTA-VDR 131
Query: 1374 NVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
V + + + +P ++ ++ P + +Y+++ +E E IS
Sbjct: 132 PVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGKEPGHFETISS 191
Query: 1431 KNITKTQTSIQ-----NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS---- 1481
+I+ + N S R+ +++ D ++ I K +S
Sbjct: 192 SHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQITNNKRRSLQQM 251
Query: 1482 PTVEKPLKN---ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXX 1534
P E+ + I + N+ +L C F G P PK W+ +G+++ A +E+
Sbjct: 252 PPTEQYVNQSSPIALQGNQH-KLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGK 310
Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
Y C F +++ + V ++ P + G++ +
Sbjct: 311 TLVFNVTQDKAGKYDC-RFATQQDIDRTFNVVVEAAPYWPLGPPP-NTNTSEGEKVIFDC 368
Query: 1595 VIEGIPPPEVIWYKNGNKLENDKE 1618
G P P+V +YKNG ++E+ K+
Sbjct: 369 TTYGKPTPKVTFYKNGVEIESQKD 392
Score = 38.3 bits (85), Expect = 0.059
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 1/75 (1%)
Query: 519 KHTPDGSTVQ-FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
K+TP Q C G PRP W + PS + +LV + D
Sbjct: 54 KNTPGNLLEQTIHCYANGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESD 113
Query: 578 AGTFTCVAKNAAGFA 592
AG + C A+N+ G A
Sbjct: 114 AGLYQCEAENSNGTA 128
Score = 37.5 bits (83), Expect = 0.10
Identities = 57/286 (19%), Positives = 99/286 (34%), Gaps = 13/286 (4%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
++E P P EG ++ +C P P + + G EI ++ IE
Sbjct: 341 VVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGT 400
Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-V 746
V K T K Y + N+ G L + +P +I+P K +
Sbjct: 401 RLTIFDVKKGT-YGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEA 457
Query: 747 RQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
G+ V L + +P + W K +D + +EG Y
Sbjct: 458 VAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYEC 517
Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864
N G A + V +PT P R +E+ + E+ + A
Sbjct: 518 IGTNKYGQATGLITLKVRKPTIVQPFP-----RVEEVRMAGEEMRLACDATADNQLEVKY 572
Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVAS 909
W + + + + ++ ++ LVI+N ++ D+ YKCV S
Sbjct: 573 EWLVDGKSLPEDRISSGHYKIDDDHSLVISN-PTQDDTAKYKCVVS 617
Score = 35.5 bits (78), Expect = 0.42
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 16/95 (16%)
Query: 859 NPVPSITWYRNNEIISPS---ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
NP PS W ++ + PS E + Q GE LV + +D E D+G Y+C A NS G +
Sbjct: 72 NPRPSYRWKKDGKTFLPSMFPEKVVQK-PGEG-SLVFSRLD-ESDAGLYQCEAENSNGTA 128
Query: 916 -SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
RV + T+++H ++T E + V++E
Sbjct: 129 VDRPVRV-----QETWIRH----FKTAEPEVVVVE 154
Score = 35.5 bits (78), Expect = 0.42
Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 22/186 (11%)
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SE 1792
+Y+FRVIA+N VG S A ++ +T P E++ + W P E
Sbjct: 722 KYVFRVIARNSVGDSAARLAKD-QCETPAKQPDKNPDEVAAKGTSPENIIVQWKPMSREE 780
Query: 1793 KNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARI-------QKLSINTTYQFRIYAR 1842
NG K K E ++ WK R+ + + Y+ ++ A
Sbjct: 781 WNGADFHYVVKYRPKDEDQRVGDWKEVAVEDPFADRVTVNLDDEKDVKPFQPYEVQVQAV 840
Query: 1843 NEIGTS--LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNGGSPIT 1898
N G + +P T + + G P S P V E + +VTL W +P++ G+ T
Sbjct: 841 NSEGRTNVVPETVEGRTGEG---VPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGN-FT 896
Query: 1899 NYIIEF 1904
Y I +
Sbjct: 897 GYKITY 902
Score = 35.5 bits (78), Expect = 0.42
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN-VTILDKPS 1382
N K+++K K ID+ S + I +EN + LR + G D + T L + +
Sbjct: 1040 NGKLVEKSCPRK-QIDADSKEIRITGLENETPYRFILRAHTSAGEGDPNSSDATTLPETT 1098
Query: 1383 P----PGKPNILE--IDSSSINICWDEPENTGNSTIIY---YVVEYQEIDTTEWISVKNI 1433
PG P+++E I N+ + + S Y V+Y+ D EW +VK
Sbjct: 1099 AAGVDPGVPSLVENAIGDKYFNVSFRPAKYDDESRAPVGNTYEVQYKPQDADEWETVKPA 1158
Query: 1434 TKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
T + L + Y R A+ +VD + ETT+
Sbjct: 1159 DDGLTVHVDGLSPGTKYDVRVAAL-QVD-PEGGETTK 1193
Score = 34.7 bits (76), Expect = 0.73
Identities = 114/567 (20%), Positives = 187/567 (32%), Gaps = 47/567 (8%)
Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYD-CDLDDAGEYSCEVGNSKCTAI---LTVEE 1193
RW KDG S + + + ++ D DAG Y CE NS TA+ + V+E
Sbjct: 78 RWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEAENSNGTAVDRPVRVQE 137
Query: 1194 PSI-NFTLRLPEFILVPANTDAYLTVEIP--DETLDVTW--YKKKSVIEDTEKFTLISDV 1248
I +F PE ++V P + V W K+ +T + IS
Sbjct: 138 TWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGKEPGHFETISSSHISSN 197
Query: 1249 KKRTLIIRKCTEDD---QCEYTCV-----LLDAKSTTKLKVEVV--------EFPPKIVD 1292
++ TL E D YTC L D K + +++ + PP
Sbjct: 198 EQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQITNNKRRSLQQMPPTEQY 257
Query: 1293 YEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
+ I +G+ L + +P P W N + I + + V
Sbjct: 258 VNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVT 317
Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKP----SPPGKPNILEIDSSSINICWDEPENT 1407
AG Y R D NV + P PP N E I C + T
Sbjct: 318 QDKAGKYDCRFATQ-QDIDRTFNVVVEAAPYWPLGPPPNTNTSE-GEKVIFDCTTYGKPT 375
Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE- 1466
T VE + ++ I T+ +I ++K +Y AV + +
Sbjct: 376 PKVTFYKNGVEIESQKDDRYL----IEGTRLTIFDVK-KGTYGKGDNAVYQCKSENKHGW 430
Query: 1467 -TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR---DGKKL 1522
T +Y + K Q ++ + + + + L C F P V W G K
Sbjct: 431 LWTNFYLNLLAFKPQL-LIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKG 489
Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
A Y+CI N +G+ T + +KP I +++
Sbjct: 490 NQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQA-TGLITLKVRKPTIVQPFPRVEE 548
Query: 1583 KHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKELKRSH 1639
G+E + A + + W +G L D+ + K + + I +
Sbjct: 549 VRMAGEEMRLACDATADNQLEVKYEWLVDGKSLPEDRISSGHYKIDDDHSLVISNPTQDD 608
Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKP 1666
++KY S E+ ++ D P
Sbjct: 609 TAKYKCVVSTKLDQVEKEIKIQFKDVP 635
Score = 31.5 bits (68), Expect = 6.8
Identities = 15/74 (20%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE--VFPED 577
+T +G V F+C G P P++T+++ I+ +D + + + +++ D
Sbjct: 357 NTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFDVKKGTYGKGD 416
Query: 578 AGTFTCVAKNAAGF 591
+ C ++N G+
Sbjct: 417 NAVYQCKSENKHGW 430
>Z93395-6|CAB07708.1| 3375|Caenorhabditis elegans Hypothetical protein
ZC101.2e protein.
Length = 3375
Score = 56.8 bits (131), Expect = 2e-07
Identities = 143/697 (20%), Positives = 267/697 (38%), Gaps = 75/697 (10%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT +P+ G C P P I W +P + +E +
Sbjct: 1885 PPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN----- 1937
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
+L +N + G YT A N GEAS + I G + P +IV GE +
Sbjct: 1938 -ILDFSNGRSELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPL 1994
Query: 753 ILSAQVVG---NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLK 806
+ + G +P P + W + P + LP T S ++ V + GVYT K
Sbjct: 1995 QVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCK 2054
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSIT 865
++ A + I V EP+ A + Q EKG +L+ T + V +
Sbjct: 2055 GSSAHATATKNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLE 2111
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGA 919
W + ++ + P++ N G L+ +G+Y+C +N SA H +
Sbjct: 2112 WEKVDDQL-PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSS 2166
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
D KV + +G ++L+C + + + G R++ E
Sbjct: 2167 ANADDEPKVEI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE- 2223
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
D GV +C V+D + LV+ QD + + +
Sbjct: 2224 -PTLEITKADPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDK 2277
Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES-- 1095
++ ++ G + D + + K+ I+ G Y C + +
Sbjct: 2278 SDASFTCPIYSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNV 2337
Query: 1096 ----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFS 1149
TA++ V + +++ + ++ G++A F+ ++T GD A++ W K+G++
Sbjct: 2338 VEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLP 2395
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV---EEPSINFTLRL 1202
+ Q+T +L D D+AG Y C + G + +L V ++ + FT+
Sbjct: 2396 PNAQVT----GGRLLFTDLKEDNAGVYRCVAKTKAGPLQTRTVLNVGSGKQDQVTFTVAD 2451
Query: 1203 PEFILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
++ AYL+ ET V W K++ + S V++ L++
Sbjct: 2452 SLPVVYTVGQPAYLSCIGKTETKPNQSVVWTKEEGDLPSG------SRVEQGVLMLPSVH 2505
Query: 1260 EDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYE 1294
DD+ YTC ++ ++ + + +++ +F P ++D E
Sbjct: 2506 RDDEGSYTCEIVKEENPVFSTVDLQIDDFIP-VIDGE 2541
Score = 51.2 bits (117), Expect = 8e-06
Identities = 92/407 (22%), Positives = 140/407 (34%), Gaps = 49/407 (12%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1609 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1661
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KP 640
C A++ D G+ + +E PP P
Sbjct: 1662 ICTARDP-----------------DTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITP 1704
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
+ Q + EG ++C + P F E V + + D VL I +
Sbjct: 1705 QTQTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGSSDDR----GVLTIPST 1757
Query: 701 KKFQEGTYTVV--AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+ G Y + N + P L + T E PP+ + + V G +
Sbjct: 1758 QLQDAGEYVCLYSPENSPPVKTNPSTLNV-TPEGTPPRPVATPPLLSVAPGSPARFNCVA 1816
Query: 759 VGNPRPTITWC--KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+ I W + N P+ DGD I+ + V G Y A N G T
Sbjct: 1817 HSDTPARIRWGFREENGPLPE-HVNQDGDDIVISEAGDRNV---GEYVCSATNDFG---T 1869
Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
V E+ EPP + + K + T +P P ITW N P
Sbjct: 1870 GVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPH 1929
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1930 DVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1971
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 38.3 bits (85), Expect = 0.059
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 16/239 (6%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
EG PP P V GS C + I W F+ E E+++ +
Sbjct: 1789 EGTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVN---QDGDD 1845
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ S NV G Y A N G P+ L++ ++ P V+EP ++ +
Sbjct: 1846 IVISEAGDRNV-----GEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEP-RTWNGKP 1899
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
GE G+P P ITW N LP +I + + G YT A
Sbjct: 1900 GERHQFRCITTGSPTPKITWTGPNG--SPLPHDVTPLEPNILDFSNGRSELNGDYTCTAS 1957
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA-RVTRNPVPSITW 866
N G A + + PP +TV E +K A +P P + W
Sbjct: 1958 NPIGEASDHGNVNIGPSLTVKTNPP---GPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 36.7 bits (81), Expect = 0.18
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+ G PP P V+EG C + IP+ I W E + + +
Sbjct: 1221 ISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGV 1272
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
+ + LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1273 YQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDR 1330
Query: 748 QGESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1331 D-QPARFKCWVPGNSNVQLRWSR 1352
Score = 35.5 bits (78), Expect = 0.42
Identities = 42/194 (21%), Positives = 66/194 (34%), Gaps = 7/194 (3%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
+ PT + +P E + CI G P PK+TW T
Sbjct: 1884 EPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNILDFSN 1943
Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV---I 1596
Y C A N GE V I + + K VG+ V
Sbjct: 1944 GRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 2003
Query: 1597 EGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
G P PEV W + D ++ T + IR + ++ YT + S+ T+
Sbjct: 2004 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSAHATA 2062
Query: 1655 SVEVTLKVYDKPSK 1668
+ + ++V + PS+
Sbjct: 2063 TKNIYIEVVE-PSR 2075
Score = 35.1 bits (77), Expect = 0.55
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 5/134 (3%)
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
YR A + + DA T K I Q P ++ P ++ E C G+
Sbjct: 1198 YRCTATTITQYATDDALLTIS--KRISGRPPQ-PVIDPP--HLVVNEGEPAAFRCWVPGI 1252
Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
P ++TW+R+ Y+ Y C A N +G ++ V
Sbjct: 1253 PDCQITWHREQLGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEV 1312
Query: 1569 QKPVITISNEDIKQ 1582
+KPVI + I+Q
Sbjct: 1313 KKPVIPPKVDPIRQ 1326
>Z93375-8|CAB07569.1| 3375|Caenorhabditis elegans Hypothetical protein
ZC101.2e protein.
Length = 3375
Score = 56.8 bits (131), Expect = 2e-07
Identities = 143/697 (20%), Positives = 267/697 (38%), Gaps = 75/697 (10%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT +P+ G C P P I W +P + +E +
Sbjct: 1885 PPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN----- 1937
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
+L +N + G YT A N GEAS + I G + P +IV GE +
Sbjct: 1938 -ILDFSNGRSELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPL 1994
Query: 753 ILSAQVVG---NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLK 806
+ + G +P P + W + P + LP T S ++ V + GVYT K
Sbjct: 1995 QVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCK 2054
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSIT 865
++ A + I V EP+ A + Q EKG +L+ T + V +
Sbjct: 2055 GSSAHATATKNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLE 2111
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGA 919
W + ++ + P++ N G L+ +G+Y+C +N SA H +
Sbjct: 2112 WEKVDDQL-PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSS 2166
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
D KV + +G ++L+C + + + G R++ E
Sbjct: 2167 ANADDEPKVEI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE- 2223
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
D GV +C V+D + LV+ QD + + +
Sbjct: 2224 -PTLEITKADPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDK 2277
Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES-- 1095
++ ++ G + D + + K+ I+ G Y C + +
Sbjct: 2278 SDASFTCPIYSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNV 2337
Query: 1096 ----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFS 1149
TA++ V + +++ + ++ G++A F+ ++T GD A++ W K+G++
Sbjct: 2338 VEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLP 2395
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV---EEPSINFTLRL 1202
+ Q+T +L D D+AG Y C + G + +L V ++ + FT+
Sbjct: 2396 PNAQVT----GGRLLFTDLKEDNAGVYRCVAKTKAGPLQTRTVLNVGSGKQDQVTFTVAD 2451
Query: 1203 PEFILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
++ AYL+ ET V W K++ + S V++ L++
Sbjct: 2452 SLPVVYTVGQPAYLSCIGKTETKPNQSVVWTKEEGDLPSG------SRVEQGVLMLPSVH 2505
Query: 1260 EDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYE 1294
DD+ YTC ++ ++ + + +++ +F P ++D E
Sbjct: 2506 RDDEGSYTCEIVKEENPVFSTVDLQIDDFIP-VIDGE 2541
Score = 51.2 bits (117), Expect = 8e-06
Identities = 92/407 (22%), Positives = 140/407 (34%), Gaps = 49/407 (12%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1609 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1661
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KP 640
C A++ D G+ + +E PP P
Sbjct: 1662 ICTARDP-----------------DTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITP 1704
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
+ Q + EG ++C + P F E V + + D VL I +
Sbjct: 1705 QTQTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGSSDDR----GVLTIPST 1757
Query: 701 KKFQEGTYTVV--AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+ G Y + N + P L + T E PP+ + + V G +
Sbjct: 1758 QLQDAGEYVCLYSPENSPPVKTNPSTLNV-TPEGTPPRPVATPPLLSVAPGSPARFNCVA 1816
Query: 759 VGNPRPTITWC--KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+ I W + N P+ DGD I+ + V G Y A N G T
Sbjct: 1817 HSDTPARIRWGFREENGPLPE-HVNQDGDDIVISEAGDRNV---GEYVCSATNDFG---T 1869
Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
V E+ EPP + + K + T +P P ITW N P
Sbjct: 1870 GVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPH 1929
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1930 DVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1971
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 38.3 bits (85), Expect = 0.059
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 16/239 (6%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
EG PP P V GS C + I W F+ E E+++ +
Sbjct: 1789 EGTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVN---QDGDD 1845
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ S NV G Y A N G P+ L++ ++ P V+EP ++ +
Sbjct: 1846 IVISEAGDRNV-----GEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEP-RTWNGKP 1899
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
GE G+P P ITW N LP +I + + G YT A
Sbjct: 1900 GERHQFRCITTGSPTPKITWTGPNG--SPLPHDVTPLEPNILDFSNGRSELNGDYTCTAS 1957
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA-RVTRNPVPSITW 866
N G A + + PP +TV E +K A +P P + W
Sbjct: 1958 NPIGEASDHGNVNIGPSLTVKTNPP---GPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 36.7 bits (81), Expect = 0.18
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+ G PP P V+EG C + IP+ I W E + + +
Sbjct: 1221 ISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGV 1272
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
+ + LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1273 YQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDR 1330
Query: 748 QGESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1331 D-QPARFKCWVPGNSNVQLRWSR 1352
Score = 35.5 bits (78), Expect = 0.42
Identities = 42/194 (21%), Positives = 66/194 (34%), Gaps = 7/194 (3%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
+ PT + +P E + CI G P PK+TW T
Sbjct: 1884 EPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNILDFSN 1943
Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV---I 1596
Y C A N GE V I + + K VG+ V
Sbjct: 1944 GRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 2003
Query: 1597 EGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
G P PEV W + D ++ T + IR + ++ YT + S+ T+
Sbjct: 2004 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSAHATA 2062
Query: 1655 SVEVTLKVYDKPSK 1668
+ + ++V + PS+
Sbjct: 2063 TKNIYIEVVE-PSR 2075
Score = 35.1 bits (77), Expect = 0.55
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 5/134 (3%)
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
YR A + + DA T K I Q P ++ P ++ E C G+
Sbjct: 1198 YRCTATTITQYATDDALLTIS--KRISGRPPQ-PVIDPP--HLVVNEGEPAAFRCWVPGI 1252
Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
P ++TW+R+ Y+ Y C A N +G ++ V
Sbjct: 1253 PDCQITWHREQLGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEV 1312
Query: 1569 QKPVITISNEDIKQ 1582
+KPVI + I+Q
Sbjct: 1313 KKPVIPPKVDPIRQ 1326
>U67954-4|AAM54180.1| 345|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform c
protein.
Length = 345
Score = 56.0 bits (129), Expect = 3e-07
Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 7/133 (5%)
Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLEN 1615
EV + V+ +Q KP++ IS + +VG++ LV V EG P P V+W K KL
Sbjct: 102 EVSVTFVIKVQVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPE 161
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSKPEGPVI 1674
D I + + I I E+K+ H+ KY A N AG+ + + V + + EG
Sbjct: 162 D----IKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREGRPG 217
Query: 1675 MREISRESVTIEW 1687
++S + + W
Sbjct: 218 PPQLSFDESELTW 230
Score = 50.4 bits (115), Expect = 1e-05
Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 14/191 (7%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDMHMYCSVLKITNVKKF 703
EG + L C V P I W E + D+ I E M SVL I V+
Sbjct: 31 EGESLTLRCE-VEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPI 89
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGE-SVILSAQVV-G 760
Y+ E E S+ V+K++ +P VI P + R GE +++++ V G
Sbjct: 90 NSANYSCALA--EPEVSVTFVIKVQV---KPLVVISPDTGVYHARVGEKNLVITCHVKEG 144
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
NP+P + W K + + G I I + KK G Y AEN G + I
Sbjct: 145 NPKPGVVWTKQAAKLPEDIKREHGGAR-IVITEVKK-HHAGKYNCLAENIAGSDRATIDI 202
Query: 821 TVEEPTEENAE 831
V EP + E
Sbjct: 203 HVAEPLQGERE 213
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 531 CQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
C V EG P+P + W +Q A K +D + + A +VI EV AG + C+A+N A
Sbjct: 139 CHVKEGNPKPGVVWTKQAA--KLPEDIKREHGG---ARIVITEVKKHHAGKYNCLAENIA 193
Query: 590 GFASSTTELIVEAPL 604
G +T ++ V PL
Sbjct: 194 GSDRATIDIHVAEPL 208
>AF456364-1|AAL60235.1| 344|Caenorhabditis elegans immunoglobulin
domain-containingprotein WRK-1C protein.
Length = 344
Score = 56.0 bits (129), Expect = 3e-07
Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 7/133 (5%)
Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLEN 1615
EV + V+ +Q KP++ IS + +VG++ LV V EG P P V+W K KL
Sbjct: 101 EVSVTFVIKVQVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPE 160
Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSKPEGPVI 1674
D I + + I I E+K+ H+ KY A N AG+ + + V + + EG
Sbjct: 161 D----IKREHGGARIVITEVKKHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREGRPG 216
Query: 1675 MREISRESVTIEW 1687
++S + + W
Sbjct: 217 PPQLSFDESELTW 229
Score = 50.4 bits (115), Expect = 1e-05
Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 14/191 (7%)
Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI---ESDMHMYCSVLKITNVKKF 703
EG + L C V P I W E + D+ I E M SVL I V+
Sbjct: 30 EGESLTLRCE-VEDPSVAIIWRKNTEVVAVDDEILDTYGGYEISMEGSTSVLTIKRVEPI 88
Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGE-SVILSAQVV-G 760
Y+ E E S+ V+K++ +P VI P + R GE +++++ V G
Sbjct: 89 NSANYSCALA--EPEVSVTFVIKVQV---KPLVVISPDTGVYHARVGEKNLVITCHVKEG 143
Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
NP+P + W K + + G I I + KK G Y AEN G + I
Sbjct: 144 NPKPGVVWTKQAAKLPEDIKREHGGAR-IVITEVKK-HHAGKYNCLAENIAGSDRATIDI 201
Query: 821 TVEEPTEENAE 831
V EP + E
Sbjct: 202 HVAEPLQGERE 212
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 531 CQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
C V EG P+P + W +Q A K +D + + A +VI EV AG + C+A+N A
Sbjct: 138 CHVKEGNPKPGVVWTKQAA--KLPEDIKREHGG---ARIVITEVKKHHAGKYNCLAENIA 192
Query: 590 GFASSTTELIVEAPL 604
G +T ++ V PL
Sbjct: 193 GSDRATIDIHVAEPL 207
>Z69664-7|CAA93513.2| 1159|Caenorhabditis elegans Hypothetical protein
K04D7.4 protein.
Length = 1159
Score = 55.6 bits (128), Expect = 4e-07
Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 9/157 (5%)
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVT----ILDKPSPPGKPNILEIDSSSINI 1399
+L + V D+G Y+ RLE + + + T ++ KP P P I + SI +
Sbjct: 99 TLRVSPVTPEDSGTYRCRLETDPLFSSPQSTATQELAVMVKPVAPSSPEIKTFTNRSITL 158
Query: 1400 CWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
W + I+ + V + + D T ++ T + NL + Y F A N
Sbjct: 159 VWTHNAARAHRPILRFSVSVRTVSDNTRFVMAAPSNATTVIVDNLSPYTLYAFSVRAENS 218
Query: 1459 VDISD-ASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
SD ETT ++ + E+ + P ++K ++NIT+E
Sbjct: 219 AGSSDFGPETT--FRTLGESPNRPPQIQK-IRNITSE 252
Score = 48.8 bits (111), Expect = 4e-05
Identities = 54/271 (19%), Positives = 99/271 (36%), Gaps = 13/271 (4%)
Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXXARIQKLSINTTYQFR 1838
N S+ + W + PI+ + V ++ + ++ + LS T Y F
Sbjct: 153 NRSITLVWTHNAARAHRPILRFSVSVRTVSDNTRFVMAAPSNATTVIVDNLSPYTLYAFS 212
Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
+ A N G+S T+G++ P Q + + TS V + T P+ G +
Sbjct: 213 VRAENSAGSSDFGPETTFRTLGESPNRPPQIQK--IRNITSECVEVTITPPDEMNGE-LD 269
Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
Y++ + V K+ + I + + I A+N G S P +
Sbjct: 270 KYLVLIQAVNETIPRKMTFDKPTSTPLTICALSPSTDYALAIEADNGFGTS-PQATLVFH 328
Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW----- 2013
E SP T + +VG + W P + ++ Y++ + + W
Sbjct: 329 TEDSVPNWSPSTI-TTLPVVGKPEITVLWPAPPLNATEKVIKYHLYYKAKNEDQWKIEHL 387
Query: 2014 -MEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
+ V K+ + DL+ N Y IR+ A
Sbjct: 388 NVSPNGVKSKLFKYRLVDLNPNTQYRIRVSA 418
Score = 44.8 bits (101), Expect = 7e-04
Identities = 49/217 (22%), Positives = 90/217 (41%), Gaps = 8/217 (3%)
Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
TY+ R+ + + +S T+ ++ + PS P + T+RS+TL WT +
Sbjct: 112 TYRCRLET-DPLFSSPQSTATQELAVMVKPVAPSSPE---IKTFTNRSITLVWTHNAARA 167
Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
PI + + +TV + ++ + ++N+ F + AEN+ G S
Sbjct: 168 HRPILRFSVSVRTVSDNT-RFVMAAPSNATTVIVDNLSPYTLYAFSVRAENSAGSSDFGP 226
Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
+ R + P+ P +IR + S V + TP + L Y + I+ V +T+
Sbjct: 227 ETTFRTLGES--PNRPPQIQKIRNITSECVEVTI-TPPDEMNGELDKYLVLIQAVNETIP 283
Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
++ + I LS + Y + I A N G S
Sbjct: 284 RKMTFDKPTSTPLTICALSPSTDYALAIEADNGFGTS 320
>Z93395-4|CAB07707.1| 2295|Caenorhabditis elegans Hypothetical protein
ZC101.2c protein.
Length = 2295
Score = 55.2 bits (127), Expect = 5e-07
Identities = 141/692 (20%), Positives = 254/692 (36%), Gaps = 79/692 (11%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1609 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1661
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
C A++ AP+ + + V + PPT +P+
Sbjct: 1662 ICTARDPD----------TGAPIDSTPATVHVTNAAAPPQVEAHQE-----PPTAVVEPR 1706
Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
G C P P I W +P + +E + +L +N +
Sbjct: 1707 TWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN------ILDFSNGR 1758
Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG- 760
G YT A N GEAS + I G + P +IV GE + + + G
Sbjct: 1759 SELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 1816
Query: 761 --NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAE 815
+P P + W + P + LP T S ++ V + GVYT K ++ A
Sbjct: 1817 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATAT 1876
Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSITWYRNNEIIS 874
+ I V EP+ A + Q EKG +L+ T + V + W + ++ +
Sbjct: 1877 KNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLEWEKVDDQL- 1932
Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGARVTIDVEKV 928
P++ N G L+ +G+Y+C +N SA H + D KV
Sbjct: 1933 PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSSANADDEPKV 1988
Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
+ +G ++L+C + + + G R++ E
Sbjct: 1989 EI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE--PTLEITKA 2044
Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D GV +C V+D + LV+ QD + + + ++ +
Sbjct: 2045 DPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDKSDASFTCPI 2099
Query: 1049 WERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES------CTAEV 1100
+ G + D + + K+ I+ G Y C + + TA++
Sbjct: 2100 YSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNVVEGFVTAQM 2159
Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDG 1158
V + +++ + ++ G++A F+ ++T GD A++ W K+G++ + Q+T
Sbjct: 2160 FVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLPPNAQVT--- 2214
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+L D D+AG Y C V +K + T
Sbjct: 2215 -GGRLLFTDLKEDNAGVYRC-VAKTKAGPLQT 2244
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 42.7 bits (96), Expect = 0.003
Identities = 68/296 (22%), Positives = 116/296 (39%), Gaps = 35/296 (11%)
Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
P Q V+EG + C + P + ++ +G +P + L+I
Sbjct: 1512 PPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLP---------AHARFSQGNLEIPR 1562
Query: 700 VKKFQEGTYTVVAV----NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
K E Y +A NR E++ P + +K+ + +I+P + V +G +
Sbjct: 1563 TLKSDEDEYICIATDPTTNRPVESN-PARVIVKSPIRP---IIDPAEQT-VPEGSPFKIR 1617
Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG--- 812
V G+P +T+ + V + + + + ++ ++ DEG Y A + +
Sbjct: 1618 CYVPGHPSVQLTF----RRVSGQLNEDADENNGLLAVQRAELTDEGDYICTARDPDTGAP 1673
Query: 813 IAETSAVITVEEPT-----EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
I T A + V E + EPP + + K + T +P P ITW
Sbjct: 1674 IDSTPATVHVTNAAAPPQVEAHQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWT 1733
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
N P + NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1734 GPNGSPLPHDVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1784
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 36.7 bits (81), Expect = 0.18
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+ G PP P V+EG C + IP+ I W E + + +
Sbjct: 1221 ISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGV 1272
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
+ + LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1273 YQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDR 1330
Query: 748 QGESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1331 D-QPARFKCWVPGNSNVQLRWSR 1352
Score = 35.9 bits (79), Expect = 0.32
Identities = 43/198 (21%), Positives = 67/198 (33%), Gaps = 7/198 (3%)
Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535
E + PT + +P E + CI G P PK+TW T
Sbjct: 1693 EAHQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNIL 1752
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
Y C A N GE V I + + K VG+ V
Sbjct: 1753 DFSNGRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCE 1812
Query: 1596 ---IEGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
G P PEV W + D ++ T + IR + ++ YT + S+
Sbjct: 1813 AFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSA 1871
Query: 1651 AGTSSVEVTLKVYDKPSK 1668
T++ + ++V + PS+
Sbjct: 1872 HATATKNIYIEVVE-PSR 1888
Score = 35.1 bits (77), Expect = 0.55
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 5/134 (3%)
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
YR A + + DA T K I Q P ++ P ++ E C G+
Sbjct: 1198 YRCTATTITQYATDDALLTIS--KRISGRPPQ-PVIDPP--HLVVNEGEPAAFRCWVPGI 1252
Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
P ++TW+R+ Y+ Y C A N +G ++ V
Sbjct: 1253 PDCQITWHREQLGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEV 1312
Query: 1569 QKPVITISNEDIKQ 1582
+KPVI + I+Q
Sbjct: 1313 KKPVIPPKVDPIRQ 1326
Score = 31.9 bits (69), Expect = 5.2
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 639 KPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K AQ V D+ SD C + ++P + W ++ ++ S A+ + + ++
Sbjct: 2079 KSHAQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGDLP-----SKAVPNG-----NKIE 2128
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
I GTY V V+ +G V QV+ + S + G+
Sbjct: 2129 IKEFDDASAGTY-VCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC 2187
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+V G+P I+W K LP + T + K + GVY A+ G +T
Sbjct: 2188 KVTGDPSAVISWTKEGN--DDLPPNAQ-VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQT 2244
Query: 817 SAVITV 822
V+ V
Sbjct: 2245 RTVLNV 2250
Score = 31.5 bits (68), Expect = 6.8
Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 5/93 (5%)
Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
P E P V + R + G QF C G P P+ITW P +
Sbjct: 1690 PQVEAHQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPL-- 1747
Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
+ N+ L E G +TC A N G AS
Sbjct: 1748 -EPNI--LDFSNGRSELNGDYTCTASNPIGEAS 1777
>Z93375-7|CAB07568.1| 2295|Caenorhabditis elegans Hypothetical protein
ZC101.2c protein.
Length = 2295
Score = 55.2 bits (127), Expect = 5e-07
Identities = 141/692 (20%), Positives = 254/692 (36%), Gaps = 79/692 (11%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1609 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1661
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
C A++ AP+ + + V + PPT +P+
Sbjct: 1662 ICTARDPD----------TGAPIDSTPATVHVTNAAAPPQVEAHQE-----PPTAVVEPR 1706
Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
G C P P I W +P + +E + +L +N +
Sbjct: 1707 TWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN------ILDFSNGR 1758
Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG- 760
G YT A N GEAS + I G + P +IV GE + + + G
Sbjct: 1759 SELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 1816
Query: 761 --NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAE 815
+P P + W + P + LP T S ++ V + GVYT K ++ A
Sbjct: 1817 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATAT 1876
Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSITWYRNNEIIS 874
+ I V EP+ A + Q EKG +L+ T + V + W + ++ +
Sbjct: 1877 KNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLEWEKVDDQL- 1932
Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGARVTIDVEKV 928
P++ N G L+ +G+Y+C +N SA H + D KV
Sbjct: 1933 PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSSANADDEPKV 1988
Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
+ +G ++L+C + + + G R++ E
Sbjct: 1989 EI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE--PTLEITKA 2044
Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
D GV +C V+D + LV+ QD + + + ++ +
Sbjct: 2045 DPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDKSDASFTCPI 2099
Query: 1049 WERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES------CTAEV 1100
+ G + D + + K+ I+ G Y C + + TA++
Sbjct: 2100 YSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNVVEGFVTAQM 2159
Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDG 1158
V + +++ + ++ G++A F+ ++T GD A++ W K+G++ + Q+T
Sbjct: 2160 FVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLPPNAQVT--- 2214
Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+L D D+AG Y C V +K + T
Sbjct: 2215 -GGRLLFTDLKEDNAGVYRC-VAKTKAGPLQT 2244
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 42.7 bits (96), Expect = 0.003
Identities = 68/296 (22%), Positives = 116/296 (39%), Gaps = 35/296 (11%)
Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
P Q V+EG + C + P + ++ +G +P + L+I
Sbjct: 1512 PPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLP---------AHARFSQGNLEIPR 1562
Query: 700 VKKFQEGTYTVVAV----NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
K E Y +A NR E++ P + +K+ + +I+P + V +G +
Sbjct: 1563 TLKSDEDEYICIATDPTTNRPVESN-PARVIVKSPIRP---IIDPAEQT-VPEGSPFKIR 1617
Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG--- 812
V G+P +T+ + V + + + + ++ ++ DEG Y A + +
Sbjct: 1618 CYVPGHPSVQLTF----RRVSGQLNEDADENNGLLAVQRAELTDEGDYICTARDPDTGAP 1673
Query: 813 IAETSAVITVEEPT-----EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
I T A + V E + EPP + + K + T +P P ITW
Sbjct: 1674 IDSTPATVHVTNAAAPPQVEAHQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWT 1733
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
N P + NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1734 GPNGSPLPHDVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1784
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 36.7 bits (81), Expect = 0.18
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+ G PP P V+EG C + IP+ I W E + + +
Sbjct: 1221 ISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGV 1272
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
+ + LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1273 YQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDR 1330
Query: 748 QGESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1331 D-QPARFKCWVPGNSNVQLRWSR 1352
Score = 35.9 bits (79), Expect = 0.32
Identities = 43/198 (21%), Positives = 67/198 (33%), Gaps = 7/198 (3%)
Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535
E + PT + +P E + CI G P PK+TW T
Sbjct: 1693 EAHQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNIL 1752
Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
Y C A N GE V I + + K VG+ V
Sbjct: 1753 DFSNGRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCE 1812
Query: 1596 ---IEGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
G P PEV W + D ++ T + IR + ++ YT + S+
Sbjct: 1813 AFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSA 1871
Query: 1651 AGTSSVEVTLKVYDKPSK 1668
T++ + ++V + PS+
Sbjct: 1872 HATATKNIYIEVVE-PSR 1888
Score = 35.1 bits (77), Expect = 0.55
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 5/134 (3%)
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
YR A + + DA T K I Q P ++ P ++ E C G+
Sbjct: 1198 YRCTATTITQYATDDALLTIS--KRISGRPPQ-PVIDPP--HLVVNEGEPAAFRCWVPGI 1252
Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
P ++TW+R+ Y+ Y C A N +G ++ V
Sbjct: 1253 PDCQITWHREQLGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEV 1312
Query: 1569 QKPVITISNEDIKQ 1582
+KPVI + I+Q
Sbjct: 1313 KKPVIPPKVDPIRQ 1326
Score = 31.9 bits (69), Expect = 5.2
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 639 KPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K AQ V D+ SD C + ++P + W ++ ++ S A+ + + ++
Sbjct: 2079 KSHAQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGDLP-----SKAVPNG-----NKIE 2128
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
I GTY V V+ +G V QV+ + S + G+
Sbjct: 2129 IKEFDDASAGTY-VCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC 2187
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+V G+P I+W K LP + T + K + GVY A+ G +T
Sbjct: 2188 KVTGDPSAVISWTKEGN--DDLPPNAQ-VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQT 2244
Query: 817 SAVITV 822
V+ V
Sbjct: 2245 RTVLNV 2250
Score = 31.5 bits (68), Expect = 6.8
Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 5/93 (5%)
Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
P E P V + R + G QF C G P P+ITW P +
Sbjct: 1690 PQVEAHQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPL-- 1747
Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
+ N+ L E G +TC A N G AS
Sbjct: 1748 -EPNI--LDFSNGRSELNGDYTCTASNPIGEAS 1777
>U49956-4|AAK77620.1| 1117|Caenorhabditis elegans Variable abnormal
morphology protein1, isoform a protein.
Length = 1117
Score = 54.4 bits (125), Expect = 8e-07
Identities = 46/211 (21%), Positives = 89/211 (42%), Gaps = 15/211 (7%)
Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
+ ++D++ PPS+P V + T+ S L W EP S GG P Y ++ + +G+
Sbjct: 327 FRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKC-SGRGE 385
Query: 1911 SWTKIVTVGG---SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL----EKHA 1963
T ++T G S I ++ + F + A+N V P S+ + +
Sbjct: 386 CGTVVMTPGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSE 445
Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD-VTKTMWMEVGKVDVN 2022
PP + L + S+ + +W + D + + + +R + K E V++
Sbjct: 446 EEDVPPVSHLRVDASQSDGITIAWSVSDSD----VSDFEVEVRPAIVKKRTFETRHVNMT 501
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
F L+ Y R+ R+++ S+P+
Sbjct: 502 YTTF--IGLNPETVYQFRVRIRDDLRWSQPI 530
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/203 (22%), Positives = 81/203 (39%), Gaps = 17/203 (8%)
Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+++ PS+P ++ I+ S + W P GG Y ++ + +
Sbjct: 334 ISMPCTQPPSRPI-KLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMT 392
Query: 1718 DVDRDVETYCIQ--KLNENCEYMFRVIAQNPVG--FSEALESEPIV-IKTAL---DVPSX 1769
D+ + T +Q L + +Y F V A+N V F E E ++ I+T DVP
Sbjct: 393 PGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPPV 452
Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKL 1829
D + I W S+ S + D++VE++ K + +
Sbjct: 453 SHLRVDASQSDG--ITIAWSVSD----SDVSDFEVEVRPAIVKKRTFETRHVNMTYTTFI 506
Query: 1830 SIN--TTYQFRIYARNEIGTSLP 1850
+N T YQFR+ R+++ S P
Sbjct: 507 GLNPETVYQFRVRIRDDLRWSQP 529
Score = 34.3 bits (75), Expect = 0.97
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWI-SVKNITKT 1436
PS P K I ++S + W+EP + G I+Y V+ E T K ++
Sbjct: 342 PSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMTPGDKKLSTR 401
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEV 1459
I L+ +S Y F +A N+V
Sbjct: 402 SVQINGLRPSSDYTFLVFAKNKV 424
>U49956-3|AAK77621.1| 1122|Caenorhabditis elegans Variable abnormal
morphology protein1, isoform b protein.
Length = 1122
Score = 54.4 bits (125), Expect = 8e-07
Identities = 46/211 (21%), Positives = 89/211 (42%), Gaps = 15/211 (7%)
Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
+ ++D++ PPS+P V + T+ S L W EP S GG P Y ++ + +G+
Sbjct: 327 FRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKC-SGRGE 385
Query: 1911 SWTKIVTVGG---SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL----EKHA 1963
T ++T G S I ++ + F + A+N V P S+ + +
Sbjct: 386 CGTVVMTPGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSE 445
Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD-VTKTMWMEVGKVDVN 2022
PP + L + S+ + +W + D + + + +R + K E V++
Sbjct: 446 EEDVPPVSHLRVDASQSDGITIAWSVSDSD----VSDFEVEVRPAIVKKRTFETRHVNMT 501
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
F L+ Y R+ R+++ S+P+
Sbjct: 502 YTTF--IGLNPETVYQFRVRIRDDLRWSQPI 530
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/203 (22%), Positives = 81/203 (39%), Gaps = 17/203 (8%)
Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+++ PS+P ++ I+ S + W P GG Y ++ + +
Sbjct: 334 ISMPCTQPPSRPI-KLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMT 392
Query: 1718 DVDRDVETYCIQ--KLNENCEYMFRVIAQNPVG--FSEALESEPIV-IKTAL---DVPSX 1769
D+ + T +Q L + +Y F V A+N V F E E ++ I+T DVP
Sbjct: 393 PGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPPV 452
Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKL 1829
D + I W S+ S + D++VE++ K + +
Sbjct: 453 SHLRVDASQSDG--ITIAWSVSD----SDVSDFEVEVRPAIVKKRTFETRHVNMTYTTFI 506
Query: 1830 SIN--TTYQFRIYARNEIGTSLP 1850
+N T YQFR+ R+++ S P
Sbjct: 507 GLNPETVYQFRVRIRDDLRWSQP 529
Score = 34.3 bits (75), Expect = 0.97
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWI-SVKNITKT 1436
PS P K I ++S + W+EP + G I+Y V+ E T K ++
Sbjct: 342 PSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMTPGDKKLSTR 401
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEV 1459
I L+ +S Y F +A N+V
Sbjct: 402 SVQINGLRPSSDYTFLVFAKNKV 424
>AF040269-1|AAC38970.1| 1122|Caenorhabditis elegans Eph receptor
tyrosine kinase protein.
Length = 1122
Score = 54.4 bits (125), Expect = 8e-07
Identities = 46/211 (21%), Positives = 89/211 (42%), Gaps = 15/211 (7%)
Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
+ ++D++ PPS+P V + T+ S L W EP S GG P Y ++ + +G+
Sbjct: 327 FRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKC-SGRGE 385
Query: 1911 SWTKIVTVGG---SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL----EKHA 1963
T ++T G S I ++ + F + A+N V P S+ + +
Sbjct: 386 CGTVVMTPGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSE 445
Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD-VTKTMWMEVGKVDVN 2022
PP + L + S+ + +W + D + + + +R + K E V++
Sbjct: 446 EEDVPPVSHLRVDASQSDGITIAWSVSDSD----VSDFEVEVRPAIVKKRTFETRHVNMT 501
Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
F L+ Y R+ R+++ S+P+
Sbjct: 502 YTTF--IGLNPETVYQFRVRIRDDLRWSQPI 530
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/203 (22%), Positives = 81/203 (39%), Gaps = 17/203 (8%)
Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
+++ PS+P ++ I+ S + W P GG Y ++ + +
Sbjct: 334 ISMPCTQPPSRPI-KLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMT 392
Query: 1718 DVDRDVETYCIQ--KLNENCEYMFRVIAQNPVG--FSEALESEPIV-IKTAL---DVPSX 1769
D+ + T +Q L + +Y F V A+N V F E E ++ I+T DVP
Sbjct: 393 PGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPPV 452
Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKL 1829
D + I W S+ S + D++VE++ K + +
Sbjct: 453 SHLRVDASQSDG--ITIAWSVSD----SDVSDFEVEVRPAIVKKRTFETRHVNMTYTTFI 506
Query: 1830 SIN--TTYQFRIYARNEIGTSLP 1850
+N T YQFR+ R+++ S P
Sbjct: 507 GLNPETVYQFRVRIRDDLRWSQP 529
Score = 34.3 bits (75), Expect = 0.97
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWI-SVKNITKT 1436
PS P K I ++S + W+EP + G I+Y V+ E T K ++
Sbjct: 342 PSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMTPGDKKLSTR 401
Query: 1437 QTSIQNLKTNSSYRFRAYAVNEV 1459
I L+ +S Y F +A N+V
Sbjct: 402 SVQINGLRPSSDYTFLVFAKNKV 424
>AF475094-1|AAL84635.1| 533|Caenorhabditis elegans SRC-1 protein.
Length = 533
Score = 53.6 bits (123), Expect = 1e-06
Identities = 20/54 (37%), Positives = 35/54 (64%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL 474
+T+ A+Y Y + D ++ +G+ +Y+LD SN DWWYV+ T + G+VP ++
Sbjct: 74 ETLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFV 127
>AF419171-1|AAN31394.1| 533|Caenorhabditis elegans protein tyrosine
kinase protein.
Length = 533
Score = 53.6 bits (123), Expect = 1e-06
Identities = 20/54 (37%), Positives = 35/54 (64%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL 474
+T+ A+Y Y + D ++ +G+ +Y+LD SN DWWYV+ T + G+VP ++
Sbjct: 74 ETLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFV 127
>AF148954-1|AAD37411.1| 4280|Caenorhabditis elegans myotactin form A
protein.
Length = 4280
Score = 53.6 bits (123), Expect = 1e-06
Identities = 84/390 (21%), Positives = 137/390 (35%), Gaps = 25/390 (6%)
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
S S+ I W DD +T + I D ++ + +VDR Y I L Y
Sbjct: 1629 SENSLHINWDVRPDDKN-RVTAFRITVVPQDGSQRSQTFNVDRATYQYRIDNLRPRTTYN 1687
Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
V A E V+ T + + S+ I W + G
Sbjct: 1688 VTVSAAT---HKEMCGGTAAVMTTDAAALTALSTAPRVIAEEPTSITIEWESRNREAGGF 1744
Query: 1799 IIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
I++Y++E +Q ++ A + L N R+ ++ S +
Sbjct: 1745 IVEYRLEGGAWQQYARRIPAHPSQTTYTATVDGLPTNAVVDLRVRVVSQ-QNEQSNPSPE 1803
Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
K P S P+ V ++ V + W P N +E G K+
Sbjct: 1804 VRARTKCSPPTSPPQGVRVDAPSTNEVRVSWARPAKNTWM-CDQMNVEISYRVGNQPEKV 1862
Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
+TV G E+ + + ++ A N VG S + QS+ + A P L +
Sbjct: 1863 LTVPGDQTEYTFP-AEPNQRWVVKLRATNQVGSSQWSPEQSITTRQGA--PG-SVRDLRV 1918
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN---TLKFNIRDLS 2032
+ + N V W P G ++GY+I+ R + E DV+ +N +DL
Sbjct: 1919 KALSPNEVHVQWLAPLVQRGT-IVGYDISYRLKHRLACPEEEPRDVSRDFVTVYNHKDLD 1977
Query: 2033 ENHT-------YMIRIYAR-NEIGLSEPLE 2054
T Y +R+ AR E+G E E
Sbjct: 1978 YTITGLLPYSLYEVRVRARTTELGPEETKE 2007
Score = 48.8 bits (111), Expect = 4e-05
Identities = 80/372 (21%), Positives = 137/372 (36%), Gaps = 30/372 (8%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
IE + SS+ + + P P + + E + S+ I W PP+D G +T+Y +
Sbjct: 2203 IEGGSYGPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDPKGY-VTQYRVS 2260
Query: 1705 KHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL----ESEPIV 1759
D+ N + V+ TY ++LN Y + A GF + ++P
Sbjct: 2261 IVSLDDVNDKKRTHIVNHPTLTYLFEELNPETSYNISISAGTKQGFGREIWTRYTTDPFN 2320
Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK---VEIKQE-GKKWKX 1815
I +P+ + +V P + G II+ + + QE G
Sbjct: 2321 IPVVGTMPTVTPDGANALDVQWNAVLD---PKNRVKGY-IIEIRNSDTPVWQEIGGVTNH 2376
Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYA---RNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
++ L +T Y RI R +G P + + G P S P N
Sbjct: 2377 DAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP---EAQARTG-CAAPLSPPTNL 2432
Query: 1873 VVSESTSRSVTLKWTEPESNGGS-PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ ++ V + W P N Y +E+ + G K + + S EH ++ K
Sbjct: 2433 NLASPSNVQVRVSWQAPNQNSWKCSAIRYKLEY--INGTEGRKQIDLPSSSIEHLFDS-K 2489
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
+ RI EN G S ++ S+ + A P P L + G ++ W P
Sbjct: 2490 SNTKWTVRIRTENDAGSSEWSKELSITTSEGA--PG-PVEGLTAKPTGPTSIVARWKPPR 2546
Query: 1992 WDGGAPLLGYNI 2003
D + GY +
Sbjct: 2547 -DPNGVITGYTL 2557
Score = 43.6 bits (98), Expect = 0.002
Identities = 91/409 (22%), Positives = 156/409 (38%), Gaps = 46/409 (11%)
Query: 1640 SSKYT--IEASNTAGTSSVEVTLKVYDKPSKPEGPV---IMREISRESVTIEWKPPLDDG 1694
++K+T I N AG+S L + P GPV + S+ WKPP D
Sbjct: 2491 NTKWTVRIRTENDAGSSEWSKELSITTSEGAP-GPVEGLTAKPTGPTSIVARWKPPRDPN 2549
Query: 1695 GLELTKY-------AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
G+ +T Y +I + P ++ I+ V + ET ++ L + Y V+A
Sbjct: 2550 GV-ITGYTLTYQLKSIGECGPRSSTPIE-KHVKNEEET--LEGLLPDSTYEIHVVAHTS- 2604
Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEI 1806
+S + + T P+ + + ITW P + I DY+ E+
Sbjct: 2605 --HAGPQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYEL 2662
Query: 1807 KQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
W R + +L T YQ R+ A N+ G P++ + + + T
Sbjct: 2663 -WSMDTWADNSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDG-PFS--EWVPFTTSAT 2718
Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P + + ++ + W P G+ I Y + + T G++ + + V E
Sbjct: 2719 NPPAPSDLQEEATFPHAIEISWLPPTPPHGN-IDFYKVRY-TPSGEANYREIRVETDRLE 2776
Query: 1925 HCIENIKEKDEIIFRIS-----AENTVGVSLPTE-----SQSVRLEKHATVPSPPTAPLE 1974
C ++ K KD + +R+S E + VS TE S L + P E
Sbjct: 2777 -CSDSNK-KDRLCYRLSDLDPEQEYDIQVSAHTEGGGWSEWSDELTSRTQQQNIPVLERE 2834
Query: 1975 IRMVG--SNIVMTSW-GTPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKV 2019
+ + SN + W G P+ D ++GY + + + W E V
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQ-DQATHVVGYVLEFKSEDDNAEWQEYNGV 2882
Score = 38.7 bits (86), Expect = 0.045
Identities = 56/230 (24%), Positives = 87/230 (37%), Gaps = 22/230 (9%)
Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNG 1893
++ ++ R E G+ P++S + I TL P PR + E T S+ ++W P
Sbjct: 2195 FKIQVATRIEGGSYGPWSS---LVIANTLQVLPDAPRAIHLIEKTDHSLHIRWVPPIDPK 2251
Query: 1894 GSPITNY---IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
G +T Y I+ V K T I V + E + + ISA G
Sbjct: 2252 GY-VTQYRVSIVSLDDVNDKKRTHI--VNHPTLTYLFEELNPETSYNISISAGTKQGFG- 2307
Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
E + +P T P + G+N + W D + GY I IR+
Sbjct: 2308 -REIWTRYTTDPFNIPVVGTMP-TVTPDGANALDVQWNA-VLDPKNRVKGYIIEIRNSDT 2364
Query: 2011 TMWMEVGKV-----DVNTLKFNIRDLSENHTYMIRIYA---RNEIGLSEP 2052
+W E+G V +T + L + Y IRI R +G+ P
Sbjct: 2365 PVWQEIGGVTNHDAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP 2414
Score = 34.3 bits (75), Expect = 0.97
Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 14/114 (12%)
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL---ENNCGHADVEMN 1374
N EW + ++K H K S D K +T+K++E ++LR+ + G E
Sbjct: 2873 NAEWQEYNGVVK---HRKTSSDYK---ITVKQLETATLYFFRLRVVGKNDKRGQPGPETK 2926
Query: 1375 -VTILDKP-SPPGKPNILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDTT 1425
T KP +PP + +D ++ I W P E+T + Y++++ ++TT
Sbjct: 2927 ETTSCGKPEAPPESLKLESLDFETLKITWTPPEESTWRCDNVEYLIDF--VNTT 2978
Score = 33.1 bits (72), Expect = 2.2
Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 1379 DKPSPPGKPNIL---EIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
D+ +P G P L +I + ++I W P + G T Y V + T + +N
Sbjct: 1394 DQAAPSGAPLYLRTEDIRPTDVSISWQAPPCLQTNGEITEYEYEVTAGDRRQTVQKTTEN 1453
Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
I T+ I+NL+ + Y + A S + + +Q+P K L
Sbjct: 1454 IRGTRAKIENLQPQTRYNVKVRAYTARGAGPWSTEVPFQTSAGQQNVQAPGFVKVL 1509
>AF148953-1|AAD37410.1| 4450|Caenorhabditis elegans myotactin form B
protein.
Length = 4450
Score = 53.6 bits (123), Expect = 1e-06
Identities = 84/390 (21%), Positives = 137/390 (35%), Gaps = 25/390 (6%)
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
S S+ I W DD +T + I D ++ + +VDR Y I L Y
Sbjct: 1629 SENSLHINWDVRPDDKN-RVTAFRITVVPQDGSQRSQTFNVDRATYQYRIDNLRPRTTYN 1687
Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
V A E V+ T + + S+ I W + G
Sbjct: 1688 VTVSAAT---HKEMCGGTAAVMTTDAAALTALSTAPRVIAEEPTSITIEWESRNREAGGF 1744
Query: 1799 IIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
I++Y++E +Q ++ A + L N R+ ++ S +
Sbjct: 1745 IVEYRLEGGAWQQYARRIPAHPSQTTYTATVDGLPTNAVVDLRVRVVSQ-QNEQSNPSPE 1803
Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
K P S P+ V ++ V + W P N +E G K+
Sbjct: 1804 VRARTKCSPPTSPPQGVRVDAPSTNEVRVSWARPAKNTWM-CDQMNVEISYRVGNQPEKV 1862
Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
+TV G E+ + + ++ A N VG S + QS+ + A P L +
Sbjct: 1863 LTVPGDQTEYTFP-AEPNQRWVVKLRATNQVGSSQWSPEQSITTRQGA--PG-SVRDLRV 1918
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN---TLKFNIRDLS 2032
+ + N V W P G ++GY+I+ R + E DV+ +N +DL
Sbjct: 1919 KALSPNEVHVQWLAPLVQRGT-IVGYDISYRLKHRLACPEEEPRDVSRDFVTVYNHKDLD 1977
Query: 2033 ENHT-------YMIRIYAR-NEIGLSEPLE 2054
T Y +R+ AR E+G E E
Sbjct: 1978 YTITGLLPYSLYEVRVRARTTELGPEETKE 2007
Score = 48.8 bits (111), Expect = 4e-05
Identities = 80/372 (21%), Positives = 137/372 (36%), Gaps = 30/372 (8%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
IE + SS+ + + P P + + E + S+ I W PP+D G +T+Y +
Sbjct: 2203 IEGGSYGPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDPKGY-VTQYRVS 2260
Query: 1705 KHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL----ESEPIV 1759
D+ N + V+ TY ++LN Y + A GF + ++P
Sbjct: 2261 IVSLDDVNDKKRTHIVNHPTLTYLFEELNPETSYNISISAGTKQGFGREIWTRYTTDPFN 2320
Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK---VEIKQE-GKKWKX 1815
I +P+ + +V P + G II+ + + QE G
Sbjct: 2321 IPVVGTMPTVTPDGANALDVQWNAVLD---PKNRVKGY-IIEIRNSDTPVWQEIGGVTNH 2376
Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYA---RNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
++ L +T Y RI R +G P + + G P S P N
Sbjct: 2377 DAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP---EAQARTG-CAAPLSPPTNL 2432
Query: 1873 VVSESTSRSVTLKWTEPESNGGS-PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ ++ V + W P N Y +E+ + G K + + S EH ++ K
Sbjct: 2433 NLASPSNVQVRVSWQAPNQNSWKCSAIRYKLEY--INGTEGRKQIDLPSSSIEHLFDS-K 2489
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
+ RI EN G S ++ S+ + A P P L + G ++ W P
Sbjct: 2490 SNTKWTVRIRTENDAGSSEWSKELSITTSEGA--PG-PVEGLTAKPTGPTSIVARWKPPR 2546
Query: 1992 WDGGAPLLGYNI 2003
D + GY +
Sbjct: 2547 -DPNGVITGYTL 2557
Score = 43.6 bits (98), Expect = 0.002
Identities = 91/409 (22%), Positives = 156/409 (38%), Gaps = 46/409 (11%)
Query: 1640 SSKYT--IEASNTAGTSSVEVTLKVYDKPSKPEGPV---IMREISRESVTIEWKPPLDDG 1694
++K+T I N AG+S L + P GPV + S+ WKPP D
Sbjct: 2491 NTKWTVRIRTENDAGSSEWSKELSITTSEGAP-GPVEGLTAKPTGPTSIVARWKPPRDPN 2549
Query: 1695 GLELTKY-------AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
G+ +T Y +I + P ++ I+ V + ET ++ L + Y V+A
Sbjct: 2550 GV-ITGYTLTYQLKSIGECGPRSSTPIE-KHVKNEEET--LEGLLPDSTYEIHVVAHTS- 2604
Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEI 1806
+S + + T P+ + + ITW P + I DY+ E+
Sbjct: 2605 --HAGPQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYEL 2662
Query: 1807 KQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
W R + +L T YQ R+ A N+ G P++ + + + T
Sbjct: 2663 -WSMDTWADNSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDG-PFS--EWVPFTTSAT 2718
Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P + + ++ + W P G+ I Y + + T G++ + + V E
Sbjct: 2719 NPPAPSDLQEEATFPHAIEISWLPPTPPHGN-IDFYKVRY-TPSGEANYREIRVETDRLE 2776
Query: 1925 HCIENIKEKDEIIFRIS-----AENTVGVSLPTE-----SQSVRLEKHATVPSPPTAPLE 1974
C ++ K KD + +R+S E + VS TE S L + P E
Sbjct: 2777 -CSDSNK-KDRLCYRLSDLDPEQEYDIQVSAHTEGGGWSEWSDELTSRTQQQNIPVLERE 2834
Query: 1975 IRMVG--SNIVMTSW-GTPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKV 2019
+ + SN + W G P+ D ++GY + + + W E V
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQ-DQATHVVGYVLEFKSEDDNAEWQEYNGV 2882
Score = 38.7 bits (86), Expect = 0.045
Identities = 56/230 (24%), Positives = 87/230 (37%), Gaps = 22/230 (9%)
Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNG 1893
++ ++ R E G+ P++S + I TL P PR + E T S+ ++W P
Sbjct: 2195 FKIQVATRIEGGSYGPWSS---LVIANTLQVLPDAPRAIHLIEKTDHSLHIRWVPPIDPK 2251
Query: 1894 GSPITNY---IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
G +T Y I+ V K T I V + E + + ISA G
Sbjct: 2252 GY-VTQYRVSIVSLDDVNDKKRTHI--VNHPTLTYLFEELNPETSYNISISAGTKQGFG- 2307
Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
E + +P T P + G+N + W D + GY I IR+
Sbjct: 2308 -REIWTRYTTDPFNIPVVGTMP-TVTPDGANALDVQWNA-VLDPKNRVKGYIIEIRNSDT 2364
Query: 2011 TMWMEVGKV-----DVNTLKFNIRDLSENHTYMIRIYA---RNEIGLSEP 2052
+W E+G V +T + L + Y IRI R +G+ P
Sbjct: 2365 PVWQEIGGVTNHDAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP 2414
Score = 34.3 bits (75), Expect = 0.97
Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 14/114 (12%)
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL---ENNCGHADVEMN 1374
N EW + ++K H K S D K +T+K++E ++LR+ + G E
Sbjct: 2873 NAEWQEYNGVVK---HRKTSSDYK---ITVKQLETATLYFFRLRVVGKNDKRGQPGPETK 2926
Query: 1375 -VTILDKP-SPPGKPNILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDTT 1425
T KP +PP + +D ++ I W P E+T + Y++++ ++TT
Sbjct: 2927 ETTSCGKPEAPPESLKLESLDFETLKITWTPPEESTWRCDNVEYLIDF--VNTT 2978
Score = 33.1 bits (72), Expect = 2.2
Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 1379 DKPSPPGKPNIL---EIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
D+ +P G P L +I + ++I W P + G T Y V + T + +N
Sbjct: 1394 DQAAPSGAPLYLRTEDIRPTDVSISWQAPPCLQTNGEITEYEYEVTAGDRRQTVQKTTEN 1453
Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
I T+ I+NL+ + Y + A S + + +Q+P K L
Sbjct: 1454 IRGTRAKIENLQPQTRYNVKVRAYTARGAGPWSTEVPFQTSAGQQNVQAPGFVKVL 1509
>AF040648-5|AAK21413.1| 4450|Caenorhabditis elegans Lethal protein
805, isoform b protein.
Length = 4450
Score = 53.6 bits (123), Expect = 1e-06
Identities = 84/390 (21%), Positives = 137/390 (35%), Gaps = 25/390 (6%)
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
S S+ I W DD +T + I D ++ + +VDR Y I L Y
Sbjct: 1629 SENSLHINWDVRPDDKN-RVTAFRITVVPQDGSQRSQTFNVDRATYQYRIDNLRPRTTYN 1687
Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
V A E V+ T + + S+ I W + G
Sbjct: 1688 VTVSAAT---HKEMCGGTAAVMTTDAAALTALSTAPRVIAEEPTSITIEWESRNREAGGF 1744
Query: 1799 IIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
I++Y++E +Q ++ A + L N R+ ++ S +
Sbjct: 1745 IVEYRLEGGAWQQYARRIPAHPSQTTYTATVDGLPTNAVVDLRVRVVSQ-QNEQSNPSPE 1803
Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
K P S P+ V ++ V + W P N +E G K+
Sbjct: 1804 VRARTKCSPPTSPPQGVRVDAPSTNEVRVSWARPAKNTWM-CDQMNVEISYRVGNQPEKV 1862
Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
+TV G E+ + + ++ A N VG S + QS+ + A P L +
Sbjct: 1863 LTVPGDQTEYTFP-AEPNQRWVVKLRATNQVGSSQWSPEQSITTRQGA--PG-SVRDLRV 1918
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN---TLKFNIRDLS 2032
+ + N V W P G ++GY+I+ R + E DV+ +N +DL
Sbjct: 1919 KALSPNEVHVQWLAPLVQRGT-IVGYDISYRLKHRLACPEEEPRDVSRDFVTVYNHKDLD 1977
Query: 2033 ENHT-------YMIRIYAR-NEIGLSEPLE 2054
T Y +R+ AR E+G E E
Sbjct: 1978 YTITGLLPYSLYEVRVRARTTELGPEETKE 2007
Score = 48.8 bits (111), Expect = 4e-05
Identities = 80/372 (21%), Positives = 137/372 (36%), Gaps = 30/372 (8%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
IE + SS+ + + P P + + E + S+ I W PP+D G +T+Y +
Sbjct: 2203 IEGGSYGPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDPKGY-VTQYRVS 2260
Query: 1705 KHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL----ESEPIV 1759
D+ N + V+ TY ++LN Y + A GF + ++P
Sbjct: 2261 IVSLDDVNDKKRTHIVNHPTLTYLFEELNPETSYNISISAGTKQGFGREIWTRYTTDPFN 2320
Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK---VEIKQE-GKKWKX 1815
I +P+ + +V P + G II+ + + QE G
Sbjct: 2321 IPVVGTMPTVTPDGANALDVQWNAVLD---PKNRVKGY-IIEIRNSDTPVWQEIGGVTNH 2376
Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYA---RNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
++ L +T Y RI R +G P + + G P S P N
Sbjct: 2377 DAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP---EAQARTG-CAAPLSPPTNL 2432
Query: 1873 VVSESTSRSVTLKWTEPESNGGS-PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ ++ V + W P N Y +E+ + G K + + S EH ++ K
Sbjct: 2433 NLASPSNVQVRVSWQAPNQNSWKCSAIRYKLEY--INGTEGRKQIDLPSSSIEHLFDS-K 2489
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
+ RI EN G S ++ S+ + A P P L + G ++ W P
Sbjct: 2490 SNTKWTVRIRTENDAGSSEWSKELSITTSEGA--PG-PVEGLTAKPTGPTSIVARWKPPR 2546
Query: 1992 WDGGAPLLGYNI 2003
D + GY +
Sbjct: 2547 -DPNGVITGYTL 2557
Score = 43.6 bits (98), Expect = 0.002
Identities = 91/409 (22%), Positives = 156/409 (38%), Gaps = 46/409 (11%)
Query: 1640 SSKYT--IEASNTAGTSSVEVTLKVYDKPSKPEGPV---IMREISRESVTIEWKPPLDDG 1694
++K+T I N AG+S L + P GPV + S+ WKPP D
Sbjct: 2491 NTKWTVRIRTENDAGSSEWSKELSITTSEGAP-GPVEGLTAKPTGPTSIVARWKPPRDPN 2549
Query: 1695 GLELTKY-------AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
G+ +T Y +I + P ++ I+ V + ET ++ L + Y V+A
Sbjct: 2550 GV-ITGYTLTYQLKSIGECGPRSSTPIE-KHVKNEEET--LEGLLPDSTYEIHVVAHTS- 2604
Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEI 1806
+S + + T P+ + + ITW P + I DY+ E+
Sbjct: 2605 --HAGPQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYEL 2662
Query: 1807 KQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
W R + +L T YQ R+ A N+ G P++ + + + T
Sbjct: 2663 -WSMDTWADNSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDG-PFS--EWVPFTTSAT 2718
Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P + + ++ + W P G+ I Y + + T G++ + + V E
Sbjct: 2719 NPPAPSDLQEEATFPHAIEISWLPPTPPHGN-IDFYKVRY-TPSGEANYREIRVETDRLE 2776
Query: 1925 HCIENIKEKDEIIFRIS-----AENTVGVSLPTE-----SQSVRLEKHATVPSPPTAPLE 1974
C ++ K KD + +R+S E + VS TE S L + P E
Sbjct: 2777 -CSDSNK-KDRLCYRLSDLDPEQEYDIQVSAHTEGGGWSEWSDELTSRTQQQNIPVLERE 2834
Query: 1975 IRMVG--SNIVMTSW-GTPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKV 2019
+ + SN + W G P+ D ++GY + + + W E V
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQ-DQATHVVGYVLEFKSEDDNAEWQEYNGV 2882
Score = 38.7 bits (86), Expect = 0.045
Identities = 56/230 (24%), Positives = 87/230 (37%), Gaps = 22/230 (9%)
Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNG 1893
++ ++ R E G+ P++S + I TL P PR + E T S+ ++W P
Sbjct: 2195 FKIQVATRIEGGSYGPWSS---LVIANTLQVLPDAPRAIHLIEKTDHSLHIRWVPPIDPK 2251
Query: 1894 GSPITNY---IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
G +T Y I+ V K T I V + E + + ISA G
Sbjct: 2252 GY-VTQYRVSIVSLDDVNDKKRTHI--VNHPTLTYLFEELNPETSYNISISAGTKQGFG- 2307
Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
E + +P T P + G+N + W D + GY I IR+
Sbjct: 2308 -REIWTRYTTDPFNIPVVGTMP-TVTPDGANALDVQWNA-VLDPKNRVKGYIIEIRNSDT 2364
Query: 2011 TMWMEVGKV-----DVNTLKFNIRDLSENHTYMIRIYA---RNEIGLSEP 2052
+W E+G V +T + L + Y IRI R +G+ P
Sbjct: 2365 PVWQEIGGVTNHDAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP 2414
Score = 34.3 bits (75), Expect = 0.97
Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 14/114 (12%)
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL---ENNCGHADVEMN 1374
N EW + ++K H K S D K +T+K++E ++LR+ + G E
Sbjct: 2873 NAEWQEYNGVVK---HRKTSSDYK---ITVKQLETATLYFFRLRVVGKNDKRGQPGPETK 2926
Query: 1375 -VTILDKP-SPPGKPNILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDTT 1425
T KP +PP + +D ++ I W P E+T + Y++++ ++TT
Sbjct: 2927 ETTSCGKPEAPPESLKLESLDFETLKITWTPPEESTWRCDNVEYLIDF--VNTT 2978
Score = 33.1 bits (72), Expect = 2.2
Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 1379 DKPSPPGKPNIL---EIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
D+ +P G P L +I + ++I W P + G T Y V + T + +N
Sbjct: 1394 DQAAPSGAPLYLRTEDIRPTDVSISWQAPPCLQTNGEITEYEYEVTAGDRRQTVQKTTEN 1453
Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
I T+ I+NL+ + Y + A S + + +Q+P K L
Sbjct: 1454 IRGTRAKIENLQPQTRYNVKVRAYTARGAGPWSTEVPFQTSAGQQNVQAPGFVKVL 1509
>AF040648-4|AAK21414.2| 4280|Caenorhabditis elegans Lethal protein
805, isoform a protein.
Length = 4280
Score = 53.6 bits (123), Expect = 1e-06
Identities = 84/390 (21%), Positives = 137/390 (35%), Gaps = 25/390 (6%)
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
S S+ I W DD +T + I D ++ + +VDR Y I L Y
Sbjct: 1629 SENSLHINWDVRPDDKN-RVTAFRITVVPQDGSQRSQTFNVDRATYQYRIDNLRPRTTYN 1687
Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
V A E V+ T + + S+ I W + G
Sbjct: 1688 VTVSAAT---HKEMCGGTAAVMTTDAAALTALSTAPRVIAEEPTSITIEWESRNREAGGF 1744
Query: 1799 IIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
I++Y++E +Q ++ A + L N R+ ++ S +
Sbjct: 1745 IVEYRLEGGAWQQYARRIPAHPSQTTYTATVDGLPTNAVVDLRVRVVSQ-QNEQSNPSPE 1803
Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
K P S P+ V ++ V + W P N +E G K+
Sbjct: 1804 VRARTKCSPPTSPPQGVRVDAPSTNEVRVSWARPAKNTWM-CDQMNVEISYRVGNQPEKV 1862
Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
+TV G E+ + + ++ A N VG S + QS+ + A P L +
Sbjct: 1863 LTVPGDQTEYTFP-AEPNQRWVVKLRATNQVGSSQWSPEQSITTRQGA--PG-SVRDLRV 1918
Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN---TLKFNIRDLS 2032
+ + N V W P G ++GY+I+ R + E DV+ +N +DL
Sbjct: 1919 KALSPNEVHVQWLAPLVQRGT-IVGYDISYRLKHRLACPEEEPRDVSRDFVTVYNHKDLD 1977
Query: 2033 ENHT-------YMIRIYAR-NEIGLSEPLE 2054
T Y +R+ AR E+G E E
Sbjct: 1978 YTITGLLPYSLYEVRVRARTTELGPEETKE 2007
Score = 48.8 bits (111), Expect = 4e-05
Identities = 80/372 (21%), Positives = 137/372 (36%), Gaps = 30/372 (8%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
IE + SS+ + + P P + + E + S+ I W PP+D G +T+Y +
Sbjct: 2203 IEGGSYGPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDPKGY-VTQYRVS 2260
Query: 1705 KHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL----ESEPIV 1759
D+ N + V+ TY ++LN Y + A GF + ++P
Sbjct: 2261 IVSLDDVNDKKRTHIVNHPTLTYLFEELNPETSYNISISAGTKQGFGREIWTRYTTDPFN 2320
Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK---VEIKQE-GKKWKX 1815
I +P+ + +V P + G II+ + + QE G
Sbjct: 2321 IPVVGTMPTVTPDGANALDVQWNAVLD---PKNRVKGY-IIEIRNSDTPVWQEIGGVTNH 2376
Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYA---RNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
++ L +T Y RI R +G P + + G P S P N
Sbjct: 2377 DAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP---EAQARTG-CAAPLSPPTNL 2432
Query: 1873 VVSESTSRSVTLKWTEPESNGGS-PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
++ ++ V + W P N Y +E+ + G K + + S EH ++ K
Sbjct: 2433 NLASPSNVQVRVSWQAPNQNSWKCSAIRYKLEY--INGTEGRKQIDLPSSSIEHLFDS-K 2489
Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
+ RI EN G S ++ S+ + A P P L + G ++ W P
Sbjct: 2490 SNTKWTVRIRTENDAGSSEWSKELSITTSEGA--PG-PVEGLTAKPTGPTSIVARWKPPR 2546
Query: 1992 WDGGAPLLGYNI 2003
D + GY +
Sbjct: 2547 -DPNGVITGYTL 2557
Score = 43.6 bits (98), Expect = 0.002
Identities = 91/409 (22%), Positives = 156/409 (38%), Gaps = 46/409 (11%)
Query: 1640 SSKYT--IEASNTAGTSSVEVTLKVYDKPSKPEGPV---IMREISRESVTIEWKPPLDDG 1694
++K+T I N AG+S L + P GPV + S+ WKPP D
Sbjct: 2491 NTKWTVRIRTENDAGSSEWSKELSITTSEGAP-GPVEGLTAKPTGPTSIVARWKPPRDPN 2549
Query: 1695 GLELTKY-------AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
G+ +T Y +I + P ++ I+ V + ET ++ L + Y V+A
Sbjct: 2550 GV-ITGYTLTYQLKSIGECGPRSSTPIE-KHVKNEEET--LEGLLPDSTYEIHVVAHTS- 2604
Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEI 1806
+S + + T P+ + + ITW P + I DY+ E+
Sbjct: 2605 --HAGPQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYEL 2662
Query: 1807 KQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
W R + +L T YQ R+ A N+ G P++ + + + T
Sbjct: 2663 -WSMDTWADNSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDG-PFS--EWVPFTTSAT 2718
Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
P P + + ++ + W P G+ I Y + + T G++ + + V E
Sbjct: 2719 NPPAPSDLQEEATFPHAIEISWLPPTPPHGN-IDFYKVRY-TPSGEANYREIRVETDRLE 2776
Query: 1925 HCIENIKEKDEIIFRIS-----AENTVGVSLPTE-----SQSVRLEKHATVPSPPTAPLE 1974
C ++ K KD + +R+S E + VS TE S L + P E
Sbjct: 2777 -CSDSNK-KDRLCYRLSDLDPEQEYDIQVSAHTEGGGWSEWSDELTSRTQQQNIPVLERE 2834
Query: 1975 IRMVG--SNIVMTSW-GTPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKV 2019
+ + SN + W G P+ D ++GY + + + W E V
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQ-DQATHVVGYVLEFKSEDDNAEWQEYNGV 2882
Score = 38.7 bits (86), Expect = 0.045
Identities = 56/230 (24%), Positives = 87/230 (37%), Gaps = 22/230 (9%)
Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNG 1893
++ ++ R E G+ P++S + I TL P PR + E T S+ ++W P
Sbjct: 2195 FKIQVATRIEGGSYGPWSS---LVIANTLQVLPDAPRAIHLIEKTDHSLHIRWVPPIDPK 2251
Query: 1894 GSPITNY---IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
G +T Y I+ V K T I V + E + + ISA G
Sbjct: 2252 GY-VTQYRVSIVSLDDVNDKKRTHI--VNHPTLTYLFEELNPETSYNISISAGTKQGFG- 2307
Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
E + +P T P + G+N + W D + GY I IR+
Sbjct: 2308 -REIWTRYTTDPFNIPVVGTMP-TVTPDGANALDVQWNA-VLDPKNRVKGYIIEIRNSDT 2364
Query: 2011 TMWMEVGKV-----DVNTLKFNIRDLSENHTYMIRIYA---RNEIGLSEP 2052
+W E+G V +T + L + Y IRI R +G+ P
Sbjct: 2365 PVWQEIGGVTNHDAGKSTYFKKLTGLDSDTLYFIRIKVVDQRQRVGVPSP 2414
Score = 34.3 bits (75), Expect = 0.97
Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 14/114 (12%)
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL---ENNCGHADVEMN 1374
N EW + ++K H K S D K +T+K++E ++LR+ + G E
Sbjct: 2873 NAEWQEYNGVVK---HRKTSSDYK---ITVKQLETATLYFFRLRVVGKNDKRGQPGPETK 2926
Query: 1375 -VTILDKP-SPPGKPNILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDTT 1425
T KP +PP + +D ++ I W P E+T + Y++++ ++TT
Sbjct: 2927 ETTSCGKPEAPPESLKLESLDFETLKITWTPPEESTWRCDNVEYLIDF--VNTT 2978
Score = 33.1 bits (72), Expect = 2.2
Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 1379 DKPSPPGKPNIL---EIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
D+ +P G P L +I + ++I W P + G T Y V + T + +N
Sbjct: 1394 DQAAPSGAPLYLRTEDIRPTDVSISWQAPPCLQTNGEITEYEYEVTAGDRRQTVQKTTEN 1453
Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
I T+ I+NL+ + Y + A S + + +Q+P K L
Sbjct: 1454 IRGTRAKIENLQPQTRYNVKVRAYTARGAGPWSTEVPFQTSAGQQNVQAPGFVKVL 1509
>AC084161-5|AAK29735.4| 533|Caenorhabditis elegans Src oncogene
related protein 1 protein.
Length = 533
Score = 53.6 bits (123), Expect = 1e-06
Identities = 20/54 (37%), Positives = 35/54 (64%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL 474
+T+ A+Y Y + D ++ +G+ +Y+LD SN DWWYV+ T + G+VP ++
Sbjct: 74 ETLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFV 127
>U80436-2|AAC71110.1| 928|Caenorhabditis elegans Uncoordinated
protein 73, isoform c protein.
Length = 928
Score = 51.6 bits (118), Expect = 6e-06
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
P +V+ ++ + G+DV + + W + K+ + ++S+ L I
Sbjct: 745 PVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQTNQLNSR---LLI 801
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
K V+ DAG Y + +N+ G ++++ P PP + + + W
Sbjct: 802 KHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEVRLKWKAESG- 860
Query: 1408 GNSTIIYYVVEYQEIDTT---EW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
+ Y +EY+ +D + W I+ NI KT S++N N SY FR +A N+
Sbjct: 861 -----LKYCIEYRILDDSSPENWLIASTNIEKTHVSLRNFARN-SYSFRVFAYNQ 909
Score = 37.5 bits (83), Expect = 0.10
Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Query: 723 IVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS 782
++L++ T E+ P V+E +K + V +G V + + + T+ W K ++
Sbjct: 735 VLLELTTCER--PVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQT 792
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
+ +S ++K K D G Y++ A+NS G+ T A ++V + + + I+ E+
Sbjct: 793 N-QLNSRLLIKHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEV 851
Query: 843 TVKEK 847
+K K
Sbjct: 852 RLKWK 856
>U80436-1|AAC71108.1| 2488|Caenorhabditis elegans Uncoordinated
protein 73, isoform a protein.
Length = 2488
Score = 51.6 bits (118), Expect = 6e-06
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
P +V+ ++ + G+DV + + W + K+ + ++S+ L I
Sbjct: 2305 PVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQTNQLNSR---LLI 2361
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
K V+ DAG Y + +N+ G ++++ P PP + + + W
Sbjct: 2362 KHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEVRLKWKAESG- 2420
Query: 1408 GNSTIIYYVVEYQEIDTT---EW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
+ Y +EY+ +D + W I+ NI KT S++N N SY FR +A N+
Sbjct: 2421 -----LKYCIEYRILDDSSPENWLIASTNIEKTHVSLRNFARN-SYSFRVFAYNQ 2469
Score = 37.5 bits (83), Expect = 0.10
Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Query: 723 IVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS 782
++L++ T E+ P V+E +K + V +G V + + + T+ W K ++
Sbjct: 2295 VLLELTTCER--PVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQT 2352
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
+ +S ++K K D G Y++ A+NS G+ T A ++V + + + I+ E+
Sbjct: 2353 N-QLNSRLLIKHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEV 2411
Query: 843 TVKEK 847
+K K
Sbjct: 2412 RLKWK 2416
>AF048834-1|AAC12931.1| 2488|Caenorhabditis elegans guanine nucleotide
exchange factorUNC-73A protein.
Length = 2488
Score = 51.6 bits (118), Expect = 6e-06
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
P +V+ ++ + G+DV + + W + K+ + ++S+ L I
Sbjct: 2305 PVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQTNQLNSR---LLI 2361
Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
K V+ DAG Y + +N+ G ++++ P PP + + + W
Sbjct: 2362 KHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEVRLKWKAESG- 2420
Query: 1408 GNSTIIYYVVEYQEIDTT---EW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
+ Y +EY+ +D + W I+ NI KT S++N N SY FR +A N+
Sbjct: 2421 -----LKYCIEYRILDDSSPENWLIASTNIEKTHVSLRNFARN-SYSFRVFAYNQ 2469
Score = 37.5 bits (83), Expect = 0.10
Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Query: 723 IVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS 782
++L++ T E+ P V+E +K + V +G V + + + T+ W K ++
Sbjct: 2295 VLLELTTCER--PVVVEDMKDIEVVEGNDVEMCPIISSHTDFTVIWHGPAVDSKRARIQT 2352
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
+ +S ++K K D G Y++ A+NS G+ T A ++V + + + I+ E+
Sbjct: 2353 N-QLNSRLLIKHVKKCDAGAYSVIAKNSFGVTSTVAFLSVISIPDPPTDFTVKISGDHEV 2411
Query: 843 TVKEK 847
+K K
Sbjct: 2412 RLKWK 2416
>AF016687-8|AAK72065.1| 737|Caenorhabditis elegans Hypothetical
protein T21D12.9c protein.
Length = 737
Score = 51.6 bits (118), Expect = 6e-06
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G T +F C G PRP+I W F Q P+ + + Y N + I V ED G +T
Sbjct: 630 GQTAKFLCAATGTPRPEIKWAFEQIPF--PAAEARRLYVTPNDDHIYIMNVTKEDQGAYT 687
Query: 583 CVAKNAAGFASSTTELIV 600
C A N AG ++ LIV
Sbjct: 688 CHATNVAGQTQASANLIV 705
Score = 40.3 bits (90), Expect = 0.015
Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L + NV Y VA NR G +K + P+ + M + G++
Sbjct: 579 LLLDNVAMTDNSEYQCVARNRFGS---DFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKF 635
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAENS 810
G PRP I W P A + + D H I I+ K +D+G YT A N
Sbjct: 636 LCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDH-IYIMNVTK-EDQGAYTCHATNV 693
Query: 811 EGIAETSAVITVEE 824
G + SA + V E
Sbjct: 694 AGQTQASANLIVFE 707
Score = 37.9 bits (84), Expect = 0.078
Identities = 28/118 (23%), Positives = 44/118 (37%), Gaps = 3/118 (2%)
Query: 1548 YKCIAFNDHG-EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
Y+C+A N G + T + + Q P T + ED+ VG G P PE+ W
Sbjct: 592 YQCVARNRFGSDFSTHVKLQVYQAPKFTYTPEDMPLL--VGQTAKFLCAATGTPRPEIKW 649
Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
+ + I I + + YT A+N AG + L V++
Sbjct: 650 AFEQIPFPAAEARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIVFE 707
Score = 33.1 bits (72), Expect = 2.2
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
+ P F +++ + T K + T P P I W +E + +
Sbjct: 614 QAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDHI 673
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I NV E D G Y C A+N AG++ A + +
Sbjct: 674 YIMNVTKE-DQGAYTCHATNVAGQTQASANLIV 705
Score = 33.1 bits (72), Expect = 2.2
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYC 692
P F+ P+ + G C P P+I W F+ E + + +D H+Y
Sbjct: 616 PKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDHIY- 674
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGE 718
I NV K +G YT A N G+
Sbjct: 675 ----IMNVTKEDQGAYTCHATNVAGQ 696
>AF016687-7|AAK72063.1| 881|Caenorhabditis elegans Hypothetical
protein T21D12.9a protein.
Length = 881
Score = 51.6 bits (118), Expect = 6e-06
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
G T +F C G PRP+I W F Q P+ + + Y N + I V ED G +T
Sbjct: 630 GQTAKFLCAATGTPRPEIKWAFEQIPF--PAAEARRLYVTPNDDHIYIMNVTKEDQGAYT 687
Query: 583 CVAKNAAGFASSTTELIV 600
C A N AG ++ LIV
Sbjct: 688 CHATNVAGQTQASANLIV 705
Score = 46.8 bits (106), Expect = 2e-04
Identities = 62/271 (22%), Positives = 104/271 (38%), Gaps = 22/271 (8%)
Query: 855 RVTRNPVPSITWYRNNEIISPSETITQN--FDGENI---ELVITNVDSEIDSGDYKCVAS 909
RV N P + + +S + T N FD + EL++ NV + D+ +Y+CVA
Sbjct: 539 RVMENGQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNV-AMTDNSEYQCVAR 597
Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEI 967
N G S V + V + + + G+T C + T KW +
Sbjct: 598 NRFG-SDFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPF 656
Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC----IVKDQETSTMLVVKETIPEFIRK- 1022
+ R + D G C + + S L+V E +
Sbjct: 657 PAAEARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIVFENFFHYPESP 716
Query: 1023 -LQDFEVKEKDVAILEV--EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
L +K++D ++ ++ S +VW+R ++I K K F I L + T
Sbjct: 717 DLSPMLIKKRDALKIDCSCDLISSRQRMVWKRQQQVILFLK-KAKFSDNDQI--LTLTQT 773
Query: 1080 SVHDEGEYSCIL--RDESCTAEVTVVELPPE 1108
+ D GEYSC L D ++T+V++ E
Sbjct: 774 TFSDSGEYSCELWVDDTILMRKITMVKVVNE 804
Score = 44.4 bits (100), Expect = 0.001
Identities = 50/217 (23%), Positives = 83/217 (38%), Gaps = 17/217 (7%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
L + NV Y VA NR G +K + P+ + M + G++
Sbjct: 579 LLLDNVAMTDNSEYQCVARNRFGS---DFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKF 635
Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAENS 810
G PRP I W P A + + D H I I+ K +D+G YT A N
Sbjct: 636 LCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDH-IYIMNVTK-EDQGAYTCHATNV 693
Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NPVPSITWYRN 869
G + SA + V E E P + +K++ +K+ + + W R
Sbjct: 694 AGQTQASANLIVFENFFHYPESP----DLSPMLIKKRDALKIDCSCDLISSRQRMVWKRQ 749
Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
++I + + +N +++ + DSG+Y C
Sbjct: 750 QQVIL---FLKKAKFSDNDQILTLTQTTFSDSGEYSC 783
Score = 39.5 bits (88), Expect = 0.026
Identities = 37/173 (21%), Positives = 66/173 (38%), Gaps = 8/173 (4%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYC 692
P F+ P+ + G C P P+I W F+ E + + +D H+Y
Sbjct: 616 PKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDHIY- 674
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
I NV K +G YT A N G+ L + P+ + L M++++ +++
Sbjct: 675 ----IMNVTKEDQGAYTCHATNVAGQTQASANLIVFENFFHYPESPD-LSPMLIKKRDAL 729
Query: 753 ILSAQV-VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
+ + + R + W + + + L D I L D G Y+
Sbjct: 730 KIDCSCDLISSRQRMVWKRQQQVILFLKKAKFSDNDQILTLTQTTFSDSGEYS 782
Score = 39.1 bits (87), Expect = 0.034
Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 10/145 (6%)
Query: 1548 YKCIAFNDHG-EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
Y+C+A N G + T + + Q P T + ED+ VG G P PE+ W
Sbjct: 592 YQCVARNRFGSDFSTHVKLQVYQAPKFTYTPEDMPLL--VGQTAKFLCAATGTPRPEIKW 649
Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK- 1665
+ + I I + + YT A+N AG + L V++
Sbjct: 650 AFEQIPFPAAEARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIVFENF 709
Query: 1666 ---PSKPE-GPVIMREISRESVTIE 1686
P P+ P+++++ R+++ I+
Sbjct: 710 FHYPESPDLSPMLIKK--RDALKID 732
Score = 33.1 bits (72), Expect = 2.2
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
+ P F +++ + T K + T P P I W +E + +
Sbjct: 614 QAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDHI 673
Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
I NV E D G Y C A+N AG++ A + +
Sbjct: 674 YIMNVTKE-DQGAYTCHATNVAGQTQASANLIV 705
>Z93395-7|CAH04744.1| 2389|Caenorhabditis elegans Hypothetical protein
ZC101.2f protein.
Length = 2389
Score = 51.2 bits (117), Expect = 8e-06
Identities = 92/407 (22%), Positives = 140/407 (34%), Gaps = 49/407 (12%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1516 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1568
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KP 640
C A++ D G+ + +E PP P
Sbjct: 1569 ICTARDP-----------------DTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITP 1611
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
+ Q + EG ++C + P F E V + + D VL I +
Sbjct: 1612 QTQTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGSSDDR----GVLTIPST 1664
Query: 701 KKFQEGTYTVV--AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+ G Y + N + P L + T E PP+ + + V G +
Sbjct: 1665 QLQDAGEYVCLYSPENSPPVKTNPSTLNV-TPEGTPPRPVATPPLLSVAPGSPARFNCVA 1723
Query: 759 VGNPRPTITWC--KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+ I W + N P+ DGD I+ + V G Y A N G T
Sbjct: 1724 HSDTPARIRWGFREENGPLPE-HVNQDGDDIVISEAGDRNV---GEYVCSATNDFG---T 1776
Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
V E+ EPP + + K + T +P P ITW N P
Sbjct: 1777 GVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPH 1836
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1837 DVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1878
Score = 47.6 bits (108), Expect = 1e-04
Identities = 121/581 (20%), Positives = 217/581 (37%), Gaps = 57/581 (9%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT +P+ G C P P I W +P + +E +
Sbjct: 1792 PPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN----- 1844
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
+L +N + G YT A N GEAS + I G + P +IV GE +
Sbjct: 1845 -ILDFSNGRSELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPL 1901
Query: 753 ILSAQVVG---NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLK 806
+ + G +P P + W + P + LP T S ++ V + GVYT K
Sbjct: 1902 QVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCK 1961
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSIT 865
++ A + I V EP+ A + Q EKG +L+ T + V +
Sbjct: 1962 GSSAHATATKNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLE 2018
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGA 919
W + ++ + P++ N G L+ +G+Y+C +N SA H +
Sbjct: 2019 WEKVDDQL-PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSS 2073
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
D KV + +G ++L+C + + + G R++ E
Sbjct: 2074 ANADDEPKVEI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE- 2130
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
D GV +C V+D + LV+ QD + + +
Sbjct: 2131 -PTLEITKADPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDK 2184
Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES-- 1095
++ ++ G + D + + K+ I+ G Y C + +
Sbjct: 2185 SDASFTCPIYSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNV 2244
Query: 1096 ----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFS 1149
TA++ V + +++ + ++ G++A F+ ++T GD A++ W K+G++
Sbjct: 2245 VEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLP 2302
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+ Q+T +L D D+AG Y C V +K + T
Sbjct: 2303 PNAQVT----GGRLLFTDLKEDNAGVYRC-VAKTKAGPLQT 2338
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 38.3 bits (85), Expect = 0.059
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 16/239 (6%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
EG PP P V GS C + I W F+ E E+++ +
Sbjct: 1696 EGTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVN---QDGDD 1752
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ S NV G Y A N G P+ L++ ++ P V+EP ++ +
Sbjct: 1753 IVISEAGDRNV-----GEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEP-RTWNGKP 1806
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
GE G+P P ITW N LP +I + + G YT A
Sbjct: 1807 GERHQFRCITTGSPTPKITWTGPNG--SPLPHDVTPLEPNILDFSNGRSELNGDYTCTAS 1864
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA-RVTRNPVPSITW 866
N G A + + PP +TV E +K A +P P + W
Sbjct: 1865 NPIGEASDHGNVNIGPSLTVKTNPP---GPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 1920
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 35.9 bits (79), Expect = 0.32
Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 12/141 (8%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G PP P V+EG C + IP+ I W E + + ++
Sbjct: 1130 GRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGVYQ 1181
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1182 TGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDRD- 1238
Query: 750 ESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1239 QPARFKCWVPGNSNVQLRWSR 1259
Score = 35.5 bits (78), Expect = 0.42
Identities = 42/194 (21%), Positives = 66/194 (34%), Gaps = 7/194 (3%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
+ PT + +P E + CI G P PK+TW T
Sbjct: 1791 EPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNILDFSN 1850
Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV---I 1596
Y C A N GE V I + + K VG+ V
Sbjct: 1851 GRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 1910
Query: 1597 EGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
G P PEV W + D ++ T + IR + ++ YT + S+ T+
Sbjct: 1911 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSAHATA 1969
Query: 1655 SVEVTLKVYDKPSK 1668
+ + ++V + PS+
Sbjct: 1970 TKNIYIEVVE-PSR 1982
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/101 (21%), Positives = 38/101 (37%), Gaps = 2/101 (1%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541
P ++ P ++ E C G+P ++TW+R+ Y+
Sbjct: 1135 PVIDPP--HLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLPHGVYQTGNALKIPQSQ 1192
Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
Y C A N +G ++ V +KPVI + I+Q
Sbjct: 1193 LHHAGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQ 1233
Score = 31.9 bits (69), Expect = 5.2
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 639 KPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K AQ V D+ SD C + ++P + W ++ ++ S A+ + + ++
Sbjct: 2173 KSHAQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGDLP-----SKAVPNG-----NKIE 2222
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
I GTY V V+ +G V QV+ + S + G+
Sbjct: 2223 IKEFDDASAGTY-VCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC 2281
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+V G+P I+W K LP + T + K + GVY A+ G +T
Sbjct: 2282 KVTGDPSAVISWTKEGN--DDLPPNAQ-VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQT 2338
Query: 817 SAVITV 822
V+ V
Sbjct: 2339 RTVLNV 2344
>Z93395-3|CAB07706.1| 2482|Caenorhabditis elegans Hypothetical protein
ZC101.2a protein.
Length = 2482
Score = 51.2 bits (117), Expect = 8e-06
Identities = 92/407 (22%), Positives = 140/407 (34%), Gaps = 49/407 (12%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1609 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1661
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KP 640
C A++ D G+ + +E PP P
Sbjct: 1662 ICTARDP-----------------DTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITP 1704
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
+ Q + EG ++C + P F E V + + D VL I +
Sbjct: 1705 QTQTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGSSDDR----GVLTIPST 1757
Query: 701 KKFQEGTYTVV--AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+ G Y + N + P L + T E PP+ + + V G +
Sbjct: 1758 QLQDAGEYVCLYSPENSPPVKTNPSTLNV-TPEGTPPRPVATPPLLSVAPGSPARFNCVA 1816
Query: 759 VGNPRPTITWC--KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+ I W + N P+ DGD I+ + V G Y A N G T
Sbjct: 1817 HSDTPARIRWGFREENGPLPE-HVNQDGDDIVISEAGDRNV---GEYVCSATNDFG---T 1869
Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
V E+ EPP + + K + T +P P ITW N P
Sbjct: 1870 GVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPH 1929
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1930 DVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1971
Score = 47.6 bits (108), Expect = 1e-04
Identities = 121/581 (20%), Positives = 217/581 (37%), Gaps = 57/581 (9%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT +P+ G C P P I W +P + +E +
Sbjct: 1885 PPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN----- 1937
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
+L +N + G YT A N GEAS + I G + P +IV GE +
Sbjct: 1938 -ILDFSNGRSELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPL 1994
Query: 753 ILSAQVVG---NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLK 806
+ + G +P P + W + P + LP T S ++ V + GVYT K
Sbjct: 1995 QVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCK 2054
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSIT 865
++ A + I V EP+ A + Q EKG +L+ T + V +
Sbjct: 2055 GSSAHATATKNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLE 2111
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGA 919
W + ++ + P++ N G L+ +G+Y+C +N SA H +
Sbjct: 2112 WEKVDDQL-PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSS 2166
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
D KV + +G ++L+C + + + G R++ E
Sbjct: 2167 ANADDEPKVEI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE- 2223
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
D GV +C V+D + LV+ QD + + +
Sbjct: 2224 -PTLEITKADPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDK 2277
Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES-- 1095
++ ++ G + D + + K+ I+ G Y C + +
Sbjct: 2278 SDASFTCPIYSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNV 2337
Query: 1096 ----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFS 1149
TA++ V + +++ + ++ G++A F+ ++T GD A++ W K+G++
Sbjct: 2338 VEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLP 2395
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+ Q+T +L D D+AG Y C V +K + T
Sbjct: 2396 PNAQVT----GGRLLFTDLKEDNAGVYRC-VAKTKAGPLQT 2431
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 38.3 bits (85), Expect = 0.059
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 16/239 (6%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
EG PP P V GS C + I W F+ E E+++ +
Sbjct: 1789 EGTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVN---QDGDD 1845
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ S NV G Y A N G P+ L++ ++ P V+EP ++ +
Sbjct: 1846 IVISEAGDRNV-----GEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEP-RTWNGKP 1899
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
GE G+P P ITW N LP +I + + G YT A
Sbjct: 1900 GERHQFRCITTGSPTPKITWTGPNG--SPLPHDVTPLEPNILDFSNGRSELNGDYTCTAS 1957
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA-RVTRNPVPSITW 866
N G A + + PP +TV E +K A +P P + W
Sbjct: 1958 NPIGEASDHGNVNIGPSLTVKTNPP---GPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 36.7 bits (81), Expect = 0.18
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+ G PP P V+EG C + IP+ I W E + + +
Sbjct: 1221 ISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGV 1272
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
+ + LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1273 YQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDR 1330
Query: 748 QGESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1331 D-QPARFKCWVPGNSNVQLRWSR 1352
Score = 35.5 bits (78), Expect = 0.42
Identities = 42/194 (21%), Positives = 66/194 (34%), Gaps = 7/194 (3%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
+ PT + +P E + CI G P PK+TW T
Sbjct: 1884 EPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNILDFSN 1943
Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV---I 1596
Y C A N GE V I + + K VG+ V
Sbjct: 1944 GRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 2003
Query: 1597 EGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
G P PEV W + D ++ T + IR + ++ YT + S+ T+
Sbjct: 2004 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSAHATA 2062
Query: 1655 SVEVTLKVYDKPSK 1668
+ + ++V + PS+
Sbjct: 2063 TKNIYIEVVE-PSR 2075
Score = 35.1 bits (77), Expect = 0.55
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 5/134 (3%)
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
YR A + + DA T K I Q P ++ P ++ E C G+
Sbjct: 1198 YRCTATTITQYATDDALLTIS--KRISGRPPQ-PVIDPP--HLVVNEGEPAAFRCWVPGI 1252
Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
P ++TW+R+ Y+ Y C A N +G ++ V
Sbjct: 1253 PDCQITWHREQLGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEV 1312
Query: 1569 QKPVITISNEDIKQ 1582
+KPVI + I+Q
Sbjct: 1313 KKPVIPPKVDPIRQ 1326
Score = 31.9 bits (69), Expect = 5.2
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 639 KPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K AQ V D+ SD C + ++P + W ++ ++ S A+ + + ++
Sbjct: 2266 KSHAQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGDLP-----SKAVPNG-----NKIE 2315
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
I GTY V V+ +G V QV+ + S + G+
Sbjct: 2316 IKEFDDASAGTY-VCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC 2374
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+V G+P I+W K LP + T + K + GVY A+ G +T
Sbjct: 2375 KVTGDPSAVISWTKEGN--DDLPPNAQ-VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQT 2431
Query: 817 SAVITV 822
V+ V
Sbjct: 2432 RTVLNV 2437
>Z93375-9|CAH04704.1| 2389|Caenorhabditis elegans Hypothetical protein
ZC101.2f protein.
Length = 2389
Score = 51.2 bits (117), Expect = 8e-06
Identities = 92/407 (22%), Positives = 140/407 (34%), Gaps = 49/407 (12%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1516 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1568
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KP 640
C A++ D G+ + +E PP P
Sbjct: 1569 ICTARDP-----------------DTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITP 1611
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
+ Q + EG ++C + P F E V + + D VL I +
Sbjct: 1612 QTQTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGSSDDR----GVLTIPST 1664
Query: 701 KKFQEGTYTVV--AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+ G Y + N + P L + T E PP+ + + V G +
Sbjct: 1665 QLQDAGEYVCLYSPENSPPVKTNPSTLNV-TPEGTPPRPVATPPLLSVAPGSPARFNCVA 1723
Query: 759 VGNPRPTITWC--KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+ I W + N P+ DGD I+ + V G Y A N G T
Sbjct: 1724 HSDTPARIRWGFREENGPLPE-HVNQDGDDIVISEAGDRNV---GEYVCSATNDFG---T 1776
Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
V E+ EPP + + K + T +P P ITW N P
Sbjct: 1777 GVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPH 1836
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1837 DVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1878
Score = 47.6 bits (108), Expect = 1e-04
Identities = 121/581 (20%), Positives = 217/581 (37%), Gaps = 57/581 (9%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT +P+ G C P P I W +P + +E +
Sbjct: 1792 PPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN----- 1844
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
+L +N + G YT A N GEAS + I G + P +IV GE +
Sbjct: 1845 -ILDFSNGRSELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPL 1901
Query: 753 ILSAQVVG---NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLK 806
+ + G +P P + W + P + LP T S ++ V + GVYT K
Sbjct: 1902 QVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCK 1961
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSIT 865
++ A + I V EP+ A + Q EKG +L+ T + V +
Sbjct: 1962 GSSAHATATKNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLE 2018
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGA 919
W + ++ + P++ N G L+ +G+Y+C +N SA H +
Sbjct: 2019 WEKVDDQL-PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSS 2073
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
D KV + +G ++L+C + + + G R++ E
Sbjct: 2074 ANADDEPKVEI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE- 2130
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
D GV +C V+D + LV+ QD + + +
Sbjct: 2131 -PTLEITKADPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDK 2184
Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES-- 1095
++ ++ G + D + + K+ I+ G Y C + +
Sbjct: 2185 SDASFTCPIYSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNV 2244
Query: 1096 ----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFS 1149
TA++ V + +++ + ++ G++A F+ ++T GD A++ W K+G++
Sbjct: 2245 VEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLP 2302
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+ Q+T +L D D+AG Y C V +K + T
Sbjct: 2303 PNAQVT----GGRLLFTDLKEDNAGVYRC-VAKTKAGPLQT 2338
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 38.3 bits (85), Expect = 0.059
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 16/239 (6%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
EG PP P V GS C + I W F+ E E+++ +
Sbjct: 1696 EGTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVN---QDGDD 1752
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ S NV G Y A N G P+ L++ ++ P V+EP ++ +
Sbjct: 1753 IVISEAGDRNV-----GEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEP-RTWNGKP 1806
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
GE G+P P ITW N LP +I + + G YT A
Sbjct: 1807 GERHQFRCITTGSPTPKITWTGPNG--SPLPHDVTPLEPNILDFSNGRSELNGDYTCTAS 1864
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA-RVTRNPVPSITW 866
N G A + + PP +TV E +K A +P P + W
Sbjct: 1865 NPIGEASDHGNVNIGPSLTVKTNPP---GPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 1920
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 35.9 bits (79), Expect = 0.32
Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 12/141 (8%)
Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
G PP P V+EG C + IP+ I W E + + ++
Sbjct: 1130 GRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGVYQ 1181
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
+ LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1182 TGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDRD- 1238
Query: 750 ESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1239 QPARFKCWVPGNSNVQLRWSR 1259
Score = 35.5 bits (78), Expect = 0.42
Identities = 42/194 (21%), Positives = 66/194 (34%), Gaps = 7/194 (3%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
+ PT + +P E + CI G P PK+TW T
Sbjct: 1791 EPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNILDFSN 1850
Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV---I 1596
Y C A N GE V I + + K VG+ V
Sbjct: 1851 GRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 1910
Query: 1597 EGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
G P PEV W + D ++ T + IR + ++ YT + S+ T+
Sbjct: 1911 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSAHATA 1969
Query: 1655 SVEVTLKVYDKPSK 1668
+ + ++V + PS+
Sbjct: 1970 TKNIYIEVVE-PSR 1982
Score = 34.7 bits (76), Expect = 0.73
Identities = 22/101 (21%), Positives = 38/101 (37%), Gaps = 2/101 (1%)
Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541
P ++ P ++ E C G+P ++TW+R+ Y+
Sbjct: 1135 PVIDPP--HLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLPHGVYQTGNALKIPQSQ 1192
Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
Y C A N +G ++ V +KPVI + I+Q
Sbjct: 1193 LHHAGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQ 1233
Score = 31.9 bits (69), Expect = 5.2
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 639 KPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K AQ V D+ SD C + ++P + W ++ ++ S A+ + + ++
Sbjct: 2173 KSHAQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGDLP-----SKAVPNG-----NKIE 2222
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
I GTY V V+ +G V QV+ + S + G+
Sbjct: 2223 IKEFDDASAGTY-VCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC 2281
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+V G+P I+W K LP + T + K + GVY A+ G +T
Sbjct: 2282 KVTGDPSAVISWTKEGN--DDLPPNAQ-VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQT 2338
Query: 817 SAVITV 822
V+ V
Sbjct: 2339 RTVLNV 2344
>Z93375-6|CAB07567.1| 2482|Caenorhabditis elegans Hypothetical protein
ZC101.2a protein.
Length = 2482
Score = 51.2 bits (117), Expect = 8e-06
Identities = 92/407 (22%), Positives = 140/407 (34%), Gaps = 49/407 (12%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1609 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1661
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KP 640
C A++ D G+ + +E PP P
Sbjct: 1662 ICTARDP-----------------DTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITP 1704
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
+ Q + EG ++C + P F E V + + D VL I +
Sbjct: 1705 QTQTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGSSDDR----GVLTIPST 1757
Query: 701 KKFQEGTYTVV--AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+ G Y + N + P L + T E PP+ + + V G +
Sbjct: 1758 QLQDAGEYVCLYSPENSPPVKTNPSTLNV-TPEGTPPRPVATPPLLSVAPGSPARFNCVA 1816
Query: 759 VGNPRPTITWC--KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+ I W + N P+ DGD I+ + V G Y A N G T
Sbjct: 1817 HSDTPARIRWGFREENGPLPE-HVNQDGDDIVISEAGDRNV---GEYVCSATNDFG---T 1869
Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
V E+ EPP + + K + T +P P ITW N P
Sbjct: 1870 GVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPH 1929
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1930 DVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1971
Score = 47.6 bits (108), Expect = 1e-04
Identities = 121/581 (20%), Positives = 217/581 (37%), Gaps = 57/581 (9%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT +P+ G C P P I W +P + +E +
Sbjct: 1885 PPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN----- 1937
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
+L +N + G YT A N GEAS + I G + P +IV GE +
Sbjct: 1938 -ILDFSNGRSELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPL 1994
Query: 753 ILSAQVVG---NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLK 806
+ + G +P P + W + P + LP T S ++ V + GVYT K
Sbjct: 1995 QVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCK 2054
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSIT 865
++ A + I V EP+ A + Q EKG +L+ T + V +
Sbjct: 2055 GSSAHATATKNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLE 2111
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGA 919
W + ++ + P++ N G L+ +G+Y+C +N SA H +
Sbjct: 2112 WEKVDDQL-PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSS 2166
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
D KV + +G ++L+C + + + G R++ E
Sbjct: 2167 ANADDEPKVEI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE- 2223
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
D GV +C V+D + LV+ QD + + +
Sbjct: 2224 -PTLEITKADPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDK 2277
Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES-- 1095
++ ++ G + D + + K+ I+ G Y C + +
Sbjct: 2278 SDASFTCPIYSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNV 2337
Query: 1096 ----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFS 1149
TA++ V + +++ + ++ G++A F+ ++T GD A++ W K+G++
Sbjct: 2338 VEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLP 2395
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+ Q+T +L D D+AG Y C V +K + T
Sbjct: 2396 PNAQVT----GGRLLFTDLKEDNAGVYRC-VAKTKAGPLQT 2431
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 38.3 bits (85), Expect = 0.059
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 16/239 (6%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
EG PP P V GS C + I W F+ E E+++ +
Sbjct: 1789 EGTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVN---QDGDD 1845
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ S NV G Y A N G P+ L++ ++ P V+EP ++ +
Sbjct: 1846 IVISEAGDRNV-----GEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEP-RTWNGKP 1899
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
GE G+P P ITW N LP +I + + G YT A
Sbjct: 1900 GERHQFRCITTGSPTPKITWTGPNG--SPLPHDVTPLEPNILDFSNGRSELNGDYTCTAS 1957
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA-RVTRNPVPSITW 866
N G A + + PP +TV E +K A +P P + W
Sbjct: 1958 NPIGEASDHGNVNIGPSLTVKTNPP---GPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 36.7 bits (81), Expect = 0.18
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+ G PP P V+EG C + IP+ I W E + + +
Sbjct: 1221 ISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGV 1272
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
+ + LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1273 YQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDR 1330
Query: 748 QGESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1331 D-QPARFKCWVPGNSNVQLRWSR 1352
Score = 35.5 bits (78), Expect = 0.42
Identities = 42/194 (21%), Positives = 66/194 (34%), Gaps = 7/194 (3%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
+ PT + +P E + CI G P PK+TW T
Sbjct: 1884 EPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNILDFSN 1943
Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV---I 1596
Y C A N GE V I + + K VG+ V
Sbjct: 1944 GRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 2003
Query: 1597 EGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
G P PEV W + D ++ T + IR + ++ YT + S+ T+
Sbjct: 2004 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSAHATA 2062
Query: 1655 SVEVTLKVYDKPSK 1668
+ + ++V + PS+
Sbjct: 2063 TKNIYIEVVE-PSR 2075
Score = 35.1 bits (77), Expect = 0.55
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 5/134 (3%)
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
YR A + + DA T K I Q P ++ P ++ E C G+
Sbjct: 1198 YRCTATTITQYATDDALLTIS--KRISGRPPQ-PVIDPP--HLVVNEGEPAAFRCWVPGI 1252
Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
P ++TW+R+ Y+ Y C A N +G ++ V
Sbjct: 1253 PDCQITWHREQLGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEV 1312
Query: 1569 QKPVITISNEDIKQ 1582
+KPVI + I+Q
Sbjct: 1313 KKPVIPPKVDPIRQ 1326
Score = 31.9 bits (69), Expect = 5.2
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 639 KPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K AQ V D+ SD C + ++P + W ++ ++ S A+ + + ++
Sbjct: 2266 KSHAQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGDLP-----SKAVPNG-----NKIE 2315
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
I GTY V V+ +G V QV+ + S + G+
Sbjct: 2316 IKEFDDASAGTY-VCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC 2374
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+V G+P I+W K LP + T + K + GVY A+ G +T
Sbjct: 2375 KVTGDPSAVISWTKEGN--DDLPPNAQ-VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQT 2431
Query: 817 SAVITV 822
V+ V
Sbjct: 2432 RTVLNV 2437
>L13458-1|AAA28156.1| 2481|Caenorhabditis elegans basement membrane
proteoglycan protein.
Length = 2481
Score = 51.2 bits (117), Expect = 8e-06
Identities = 92/407 (22%), Positives = 140/407 (34%), Gaps = 49/407 (12%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
P+GS + C V G+P Q+T+ R + + D +N L ++ D G +
Sbjct: 1608 PEGSPFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-------ENNGLLAVQRAELTDEGDY 1660
Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KP 640
C A++ D G+ + +E PP P
Sbjct: 1661 ICTARDP-----------------DTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITP 1703
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
+ Q + EG ++C + P F E V + + D VL I +
Sbjct: 1704 QTQTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGSSDDR----GVLTIPST 1756
Query: 701 KKFQEGTYTVV--AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
+ G Y + N + P L + T E PP+ + + V G +
Sbjct: 1757 QLQDAGEYVCLYSPENSPPVKTNPSTLNV-TPEGTPPRPVATPPLLSVAPGSPARFNCVA 1815
Query: 759 VGNPRPTITWC--KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+ I W + N P+ DGD I+ + V G Y A N G T
Sbjct: 1816 HSDTPARIRWGFREENGPLPE-HVNQDGDDIVISEAGDRNV---GEYVCSATNDFG---T 1868
Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
V E+ EPP + + K + T +P P ITW N P
Sbjct: 1869 GVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPH 1928
Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+ NI L +N SE++ GDY C ASN G++S V I
Sbjct: 1929 DVTPLE---PNI-LDFSNGRSELN-GDYTCTASNPIGEASDHGNVNI 1970
Score = 47.6 bits (108), Expect = 1e-04
Identities = 121/581 (20%), Positives = 217/581 (37%), Gaps = 57/581 (9%)
Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
PPT +P+ G C P P I W +P + +E +
Sbjct: 1884 PPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHD--VTPLEPN----- 1936
Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
+L +N + G YT A N GEAS + I G + P +IV GE +
Sbjct: 1937 -ILDFSNGRSELNGDYTCTASNPIGEASDHGNVNI--GPSLTVKTNPPGPKLIVTVGEPL 1993
Query: 753 ILSAQVVG---NPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTLK 806
+ + G +P P + W + P + LP T S ++ V + GVYT K
Sbjct: 1994 QVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCK 2053
Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP-VPSIT 865
++ A + I V EP+ A + Q EKG +L+ T + V +
Sbjct: 2054 GSSAHATATKNIYIEVVEPS-RIATVSILGGSSQWFDQGEKG--ELICTATGSSLVDRLE 2110
Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC--VASN----SAGKSSHGA 919
W + ++ + P++ N G L+ +G+Y+C +N SA H +
Sbjct: 2111 WEKVDDQL-PTDVEEHNEPG----LLHFPSFKNSYAGEYRCNGYRNNEIIASAAVHVHSS 2165
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
D KV + +G ++L+C + + + G R++ E
Sbjct: 2166 ANADDEPKVEI--EPPRVRVVSQGDNIVLKCSVQGAENGEHFKWALLRGGSLVRQLGTE- 2222
Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
D GV +C V+D + LV+ QD + + +
Sbjct: 2223 -PTLEITKADPSNDFGVYRCNVED---NNGLVIGSAFTAVSVGQQD--KSHAQIVKFDDK 2276
Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRG--HIRKLYIRNTSVHDEGEYSCILRDES-- 1095
++ ++ G + D + + K+ I+ G Y C + +
Sbjct: 2277 SDASFTCPIYSVPGSKVDWTYENGDLPSKAVPNGNKIEIKEFDDASAGTYVCKVSFDGNV 2336
Query: 1096 ----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFS 1149
TA++ V + +++ + ++ G++A F+ ++T GD A++ W K+G++
Sbjct: 2337 VEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDCKVT-GDPSAVISWTKEGND-DLP 2394
Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
+ Q+T +L D D+AG Y C V +K + T
Sbjct: 2395 PNAQVT----GGRLLFTDLKEDNAGVYRC-VAKTKAGPLQT 2430
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 38.3 bits (85), Expect = 0.059
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 16/239 (6%)
Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
EG PP P V GS C + I W F+ E E+++ +
Sbjct: 1788 EGTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVN---QDGDD 1844
Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
+ S NV G Y A N G P+ L++ ++ P V+EP ++ +
Sbjct: 1845 IVISEAGDRNV-----GEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEP-RTWNGKP 1898
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
GE G+P P ITW N LP +I + + G YT A
Sbjct: 1899 GERHQFRCITTGSPTPKITWTGPNG--SPLPHDVTPLEPNILDFSNGRSELNGDYTCTAS 1956
Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA-RVTRNPVPSITW 866
N G A + + PP +TV E +K A +P P + W
Sbjct: 1957 NPIGEASDHGNVNIGPSLTVKTNPP---GPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2012
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
Score = 36.7 bits (81), Expect = 0.18
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)
Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
+ G PP P V+EG C + IP+ I W E + + +
Sbjct: 1220 ISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITW--------HREQLGGPLPHGV 1271
Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
+ + LKI + G Y A N+ G S P VL++K PP+V +P++ + R
Sbjct: 1272 YQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKK-PVIPPKV-DPIRQTVDR 1329
Query: 748 QGESVILSAQVVGNPRPTITWCK 770
+ V GN + W +
Sbjct: 1330 D-QPARFKCWVPGNSNVQLRWSR 1351
Score = 35.5 bits (78), Expect = 0.42
Identities = 42/194 (21%), Positives = 66/194 (34%), Gaps = 7/194 (3%)
Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
+ PT + +P E + CI G P PK+TW T
Sbjct: 1883 EPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWTGPNGSPLPHDVTPLEPNILDFSN 1942
Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV---I 1596
Y C A N GE V I + + K VG+ V
Sbjct: 1943 GRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGA 2002
Query: 1597 EGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
G P PEV W + D ++ T + IR + ++ YT + S+ T+
Sbjct: 2003 PGDPEPEVEWLHDPGPERGDLPDDFKPVTISE-QFIRHPNVGLGNAGVYTCKGSSAHATA 2061
Query: 1655 SVEVTLKVYDKPSK 1668
+ + ++V + PS+
Sbjct: 2062 TKNIYIEVVE-PSR 2074
Score = 35.1 bits (77), Expect = 0.55
Identities = 31/134 (23%), Positives = 49/134 (36%), Gaps = 5/134 (3%)
Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
YR A + + DA T K I Q P ++ P ++ E C G+
Sbjct: 1197 YRCTATTITQYATDDALLTIS--KRISGRPPQ-PVIDPP--HLVVNEGEPAAFRCWVPGI 1251
Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
P ++TW+R+ Y+ Y C A N +G ++ V
Sbjct: 1252 PDCQITWHREQLGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEV 1311
Query: 1569 QKPVITISNEDIKQ 1582
+KPVI + I+Q
Sbjct: 1312 KKPVIPPKVDPIRQ 1325
Score = 31.9 bits (69), Expect = 5.2
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 639 KPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
K AQ V D+ SD C + ++P + W ++ ++ S A+ + + ++
Sbjct: 2265 KSHAQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGDLP-----SKAVPNG-----NKIE 2314
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
I GTY V V+ +G V QV+ + S + G+
Sbjct: 2315 IKEFDDASAGTY-VCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC 2373
Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
+V G+P I+W K LP + T + K + GVY A+ G +T
Sbjct: 2374 KVTGDPSAVISWTKEGN--DDLPPNAQ-VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQT 2430
Query: 817 SAVITV 822
V+ V
Sbjct: 2431 RTVLNV 2436
>Z83123-13|CAB05615.2| 1208|Caenorhabditis elegans Hypothetical
protein C25G4.10 protein.
Length = 1208
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
T PS P N +SE T+ SVT++WTEP SN + NY + + K + + TV +
Sbjct: 265 THPSAPGNVTISELTAHSVTVQWTEPNSN-AHLVENYTLFIR--KNEHGEAVRTVKNVIS 321
Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
H + E + + + + G SLP+ ++
Sbjct: 322 PHVELGLDPDSEYVLTLQSHSANGTSLPSTAK 353
Score = 31.5 bits (68), Expect = 6.8
Identities = 23/109 (21%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTS 1439
PS PG I E+ + S+ + W EP N+ + Y + ++ + E + +VKN+
Sbjct: 267 PSAPGNVTISELTAHSVTVQWTEP-NSNAHLVENYTLFIRKNEHGEAVRTVKNVISPHVE 325
Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
+ L +S Y + + + + T + + + T+ T+ +P+
Sbjct: 326 L-GLDPDSEYVLTLQS-HSANGTSLPSTAKLFSTLPTTRPPLCTIGEPI 372
Score = 31.5 bits (68), Expect = 6.8
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 8/132 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY--QEIDTTE---WISVKNI 1433
D+P P K I +N+ WD N+ ++ +EY +DT + W +++
Sbjct: 602 DRPVAPEKLRISWNSGPRVNVTWDPVSVRRNAEVVTKPIEYTIYYLDTEQSSTWTTLRT- 660
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNI 1491
+T +++L+ ++ Y A + S +S + PT +E K+
Sbjct: 661 NQTWVVMRDLRKDALYYVYVTAKEDNRTSRSSSIITILAQKDSPGLPEPTIVIEPDHKDG 720
Query: 1492 TTEPNEDIELTC 1503
P E I + C
Sbjct: 721 VFSPGEKISINC 732
>Z83123-2|CAB05606.1| 1014|Caenorhabditis elegans Hypothetical protein
T04A11.3 protein.
Length = 1014
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
T PS P N +SE T+ SVT++WTEP SN + NY + + K + + TV +
Sbjct: 86 THPSAPGNVTISELTAHSVTVQWTEPNSN-AHLVENYTLFIR--KNEHGEAVRTVKNVIS 142
Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
H + E + + + + G SLP+ ++
Sbjct: 143 PHVELGLDPDSEYVLTLQSHSANGTSLPSTAK 174
Score = 31.5 bits (68), Expect = 6.8
Identities = 23/109 (21%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTS 1439
PS PG I E+ + S+ + W EP N+ + Y + ++ + E + +VKN+
Sbjct: 88 PSAPGNVTISELTAHSVTVQWTEP-NSNAHLVENYTLFIRKNEHGEAVRTVKNVISPHVE 146
Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
+ L +S Y + + + + T + + + T+ T+ +P+
Sbjct: 147 L-GLDPDSEYVLTLQS-HSANGTSLPSTAKLFSTLPTTRPPLCTIGEPI 193
>Z81017-11|CAE47468.1| 1051|Caenorhabditis elegans Hypothetical
protein F58A3.2e protein.
Length = 1051
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
P G T++ C+ +GYP PQI W++ ++K S Y+ N +L + + D+G
Sbjct: 305 PAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 581 FTCVAKNAAGFASSTTELIV 600
F C A N G A +I+
Sbjct: 365 FHCEALNKVGSAKKYFHVII 384
Score = 46.0 bits (104), Expect = 3e-04
Identities = 52/201 (25%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYT 804
G ++ L+ + G P P I W KN K +K +S G ++ V D G +
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 366
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPS 863
+A N G A+ + + PP+ + N +V T +V + +P
Sbjct: 367 CEALNKVGSAKKYFHVII---VNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 864 ITWYRNNEI--------ISPSE-----TITQNFD-------GENIELVITNVDSEIDSGD 903
I W R N+I S E T FD G+ L I NV + D G
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLD-DQGI 482
Query: 904 YKCVASNSAGKSSHGARVTID 924
Y C++ NS G S A +T++
Sbjct: 483 YACLSGNSLGMSMANATLTVN 503
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K K +E Y++ + T IT EEP + + + F E G T+K
Sbjct: 254 KENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVL--FNETHALPAGRTLK 311
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASN 910
L R P P I WY+N +++ S + ++ + + D+ + DSG++ C A N
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALN 371
Query: 911 SAGKSSHGARVTI 923
G + V I
Sbjct: 372 KVGSAKKYFHVII 384
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE---NRXXXXXXXXXXXXXXXYKCIA 1552
++L C G P+P++ WY++GK LK + A YE NR + C A
Sbjct: 310 LKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEA 369
Query: 1553 FNDHGEVET---SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
N G + +V ++P I + N Q + D + P +IW +
Sbjct: 370 LNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRI 429
Query: 1610 GNKLENDKEYNITTKEK 1626
NK+ Y + E+
Sbjct: 430 -NKINGSYSYYNNSAEE 445
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L CR PEP I W G+ + S E + + L++ + G
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWS--LEVEDAVVADSGE 364
Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
+ A+N+ G A + I + PP ++ L + V ++ +VV + P I
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHI 424
Query: 767 TWCKNNKPVKALP-------------TKSD----------GDTHSITILKPKKVKDEGVY 803
W + NK + T+ D GD ++TI + D+G+Y
Sbjct: 425 IWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFN-VSLDDQGIY 483
Query: 804 TLKAENSEGIAETSAVITVEE 824
+ NS G++ +A +TV E
Sbjct: 484 ACLSGNSLGMSMANATLTVNE 504
Score = 37.5 bits (83), Expect = 0.10
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1260 EDDQCEYTC---VLLDAKSTTKLKVEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDY 1311
ED++ +Y+ V DA T+L + E P IV + + + G + L
Sbjct: 258 EDEEEDYSVSQPVAPDA-GLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRA 316
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHA 1369
+ +P+P W N K++KK + K SL ++ D+G + N G A
Sbjct: 317 KGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSA 376
Query: 1370 DVEMNVTILDKPSPPG--KPNILEIDSSSIN 1398
+V I+++ P PNIL S +IN
Sbjct: 377 KKYFHVIIVNRMRRPPIIVPNILANQSVNIN 407
Score = 34.3 bits (75), Expect = 0.97
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1320 EWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
EW N K++K + K I D+ L +K ++ +D G++ R+ N G V +
Sbjct: 67 EWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEV 126
Query: 1378 LD 1379
+D
Sbjct: 127 ID 128
Score = 33.1 bits (72), Expect = 2.2
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++F+CQ + W+R ++K Q D D+N L ++ + D G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 582 TCVAKNAAGFASS--TTELI 599
+C NA G S T E+I
Sbjct: 108 SCRVHNAYGQISRNFTVEVI 127
>Z81017-10|CAD44136.1| 1096|Caenorhabditis elegans Hypothetical
protein F58A3.2d protein.
Length = 1096
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
P G T++ C+ +GYP PQI W++ ++K S Y+ N +L + + D+G
Sbjct: 305 PAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 581 FTCVAKNAAGFASSTTELIV 600
F C A N G A +I+
Sbjct: 365 FHCEALNKVGSAKKYFHVII 384
Score = 46.0 bits (104), Expect = 3e-04
Identities = 52/201 (25%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYT 804
G ++ L+ + G P P I W KN K +K +S G ++ V D G +
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 366
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPS 863
+A N G A+ + + PP+ + N +V T +V + +P
Sbjct: 367 CEALNKVGSAKKYFHVII---VNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 864 ITWYRNNEI--------ISPSE-----TITQNFD-------GENIELVITNVDSEIDSGD 903
I W R N+I S E T FD G+ L I NV + D G
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLD-DQGI 482
Query: 904 YKCVASNSAGKSSHGARVTID 924
Y C++ NS G S A +T++
Sbjct: 483 YACLSGNSLGMSMANATLTVN 503
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K K +E Y++ + T IT EEP + + + F E G T+K
Sbjct: 254 KENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVL--FNETHALPAGRTLK 311
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASN 910
L R P P I WY+N +++ S + ++ + + D+ + DSG++ C A N
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALN 371
Query: 911 SAGKSSHGARVTI 923
G + V I
Sbjct: 372 KVGSAKKYFHVII 384
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE---NRXXXXXXXXXXXXXXXYKCIA 1552
++L C G P+P++ WY++GK LK + A YE NR + C A
Sbjct: 310 LKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEA 369
Query: 1553 FNDHGEVET---SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
N G + +V ++P I + N Q + D + P +IW +
Sbjct: 370 LNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRI 429
Query: 1610 GNKLENDKEYNITTKEK 1626
NK+ Y + E+
Sbjct: 430 -NKINGSYSYYNNSAEE 445
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L CR PEP I W G+ + S E + + L++ + G
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWS--LEVEDAVVADSGE 364
Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
+ A+N+ G A + I + PP ++ L + V ++ +VV + P I
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHI 424
Query: 767 TWCKNNKPVKALP-------------TKSD----------GDTHSITILKPKKVKDEGVY 803
W + NK + T+ D GD ++TI + D+G+Y
Sbjct: 425 IWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFN-VSLDDQGIY 483
Query: 804 TLKAENSEGIAETSAVITVEE 824
+ NS G++ +A +TV E
Sbjct: 484 ACLSGNSLGMSMANATLTVNE 504
Score = 37.5 bits (83), Expect = 0.10
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1260 EDDQCEYTC---VLLDAKSTTKLKVEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDY 1311
ED++ +Y+ V DA T+L + E P IV + + + G + L
Sbjct: 258 EDEEEDYSVSQPVAPDA-GLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRA 316
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHA 1369
+ +P+P W N K++KK + K SL ++ D+G + N G A
Sbjct: 317 KGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSA 376
Query: 1370 DVEMNVTILDKPSPPG--KPNILEIDSSSIN 1398
+V I+++ P PNIL S +IN
Sbjct: 377 KKYFHVIIVNRMRRPPIIVPNILANQSVNIN 407
Score = 34.3 bits (75), Expect = 0.97
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1320 EWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
EW N K++K + K I D+ L +K ++ +D G++ R+ N G V +
Sbjct: 67 EWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEV 126
Query: 1378 LD 1379
+D
Sbjct: 127 ID 128
Score = 33.1 bits (72), Expect = 2.2
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++F+CQ + W+R ++K Q D D+N L ++ + D G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 582 TCVAKNAAGFASS--TTELI 599
+C NA G S T E+I
Sbjct: 108 SCRVHNAYGQISRNFTVEVI 127
>Z81017-9|CAC70095.1| 1128|Caenorhabditis elegans Hypothetical
protein F58A3.2c protein.
Length = 1128
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
P G T++ C+ +GYP PQI W++ ++K S Y+ N +L + + D+G
Sbjct: 305 PAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 581 FTCVAKNAAGFASSTTELIV 600
F C A N G A +I+
Sbjct: 365 FHCEALNKVGSAKKYFHVII 384
Score = 46.0 bits (104), Expect = 3e-04
Identities = 52/201 (25%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYT 804
G ++ L+ + G P P I W KN K +K +S G ++ V D G +
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 366
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPS 863
+A N G A+ + + PP+ + N +V T +V + +P
Sbjct: 367 CEALNKVGSAKKYFHVII---VNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 864 ITWYRNNEI--------ISPSE-----TITQNFD-------GENIELVITNVDSEIDSGD 903
I W R N+I S E T FD G+ L I NV + D G
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLD-DQGI 482
Query: 904 YKCVASNSAGKSSHGARVTID 924
Y C++ NS G S A +T++
Sbjct: 483 YACLSGNSLGMSMANATLTVN 503
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K K +E Y++ + T IT EEP + + + F E G T+K
Sbjct: 254 KENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVL--FNETHALPAGRTLK 311
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASN 910
L R P P I WY+N +++ S + ++ + + D+ + DSG++ C A N
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALN 371
Query: 911 SAGKSSHGARVTI 923
G + V I
Sbjct: 372 KVGSAKKYFHVII 384
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE---NRXXXXXXXXXXXXXXXYKCIA 1552
++L C G P+P++ WY++GK LK + A YE NR + C A
Sbjct: 310 LKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEA 369
Query: 1553 FNDHGEVET---SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
N G + +V ++P I + N Q + D + P +IW +
Sbjct: 370 LNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRI 429
Query: 1610 GNKLENDKEYNITTKEK 1626
NK+ Y + E+
Sbjct: 430 -NKINGSYSYYNNSAEE 445
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L CR PEP I W G+ + S E + + L++ + G
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWS--LEVEDAVVADSGE 364
Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
+ A+N+ G A + I + PP ++ L + V ++ +VV + P I
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHI 424
Query: 767 TWCKNNKPVKALP-------------TKSD----------GDTHSITILKPKKVKDEGVY 803
W + NK + T+ D GD ++TI + D+G+Y
Sbjct: 425 IWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFN-VSLDDQGIY 483
Query: 804 TLKAENSEGIAETSAVITVEE 824
+ NS G++ +A +TV E
Sbjct: 484 ACLSGNSLGMSMANATLTVNE 504
Score = 37.5 bits (83), Expect = 0.10
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1260 EDDQCEYTC---VLLDAKSTTKLKVEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDY 1311
ED++ +Y+ V DA T+L + E P IV + + + G + L
Sbjct: 258 EDEEEDYSVSQPVAPDA-GLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRA 316
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHA 1369
+ +P+P W N K++KK + K SL ++ D+G + N G A
Sbjct: 317 KGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSA 376
Query: 1370 DVEMNVTILDKPSPPG--KPNILEIDSSSIN 1398
+V I+++ P PNIL S +IN
Sbjct: 377 KKYFHVIIVNRMRRPPIIVPNILANQSVNIN 407
Score = 34.3 bits (75), Expect = 0.97
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1320 EWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
EW N K++K + K I D+ L +K ++ +D G++ R+ N G V +
Sbjct: 67 EWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEV 126
Query: 1378 LD 1379
+D
Sbjct: 127 ID 128
Score = 33.1 bits (72), Expect = 2.2
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++F+CQ + W+R ++K Q D D+N L ++ + D G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 582 TCVAKNAAGFASS--TTELI 599
+C NA G S T E+I
Sbjct: 108 SCRVHNAYGQISRNFTVEVI 127
>Z81017-8|CAC70094.2| 988|Caenorhabditis elegans Hypothetical
protein F58A3.2b protein.
Length = 988
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
P G T++ C+ +GYP PQI W++ ++K S Y+ N +L + + D+G
Sbjct: 253 PAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 312
Query: 581 FTCVAKNAAGFASSTTELIV 600
F C A N G A +I+
Sbjct: 313 FHCEALNKVGSAKKYFHVII 332
Score = 46.0 bits (104), Expect = 3e-04
Identities = 52/201 (25%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYT 804
G ++ L+ + G P P I W KN K +K +S G ++ V D G +
Sbjct: 255 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 314
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPS 863
+A N G A+ + + PP+ + N +V T +V + +P
Sbjct: 315 CEALNKVGSAKKYFHVII---VNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPH 371
Query: 864 ITWYRNNEI--------ISPSE-----TITQNFD-------GENIELVITNVDSEIDSGD 903
I W R N+I S E T FD G+ L I NV + D G
Sbjct: 372 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLD-DQGI 430
Query: 904 YKCVASNSAGKSSHGARVTID 924
Y C++ NS G S A +T++
Sbjct: 431 YACLSGNSLGMSMANATLTVN 451
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K K +E Y++ + T IT EEP + + + F E G T+K
Sbjct: 202 KENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVL--FNETHALPAGRTLK 259
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASN 910
L R P P I WY+N +++ S + ++ + + D+ + DSG++ C A N
Sbjct: 260 LNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALN 319
Query: 911 SAGKSSHGARVTI 923
G + V I
Sbjct: 320 KVGSAKKYFHVII 332
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE---NRXXXXXXXXXXXXXXXYKCIA 1552
++L C G P+P++ WY++GK LK + A YE NR + C A
Sbjct: 258 LKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEA 317
Query: 1553 FNDHGEVET---SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
N G + +V ++P I + N Q + D + P +IW +
Sbjct: 318 LNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRI 377
Query: 1610 GNKLENDKEYNITTKEK 1626
NK+ Y + E+
Sbjct: 378 -NKINGSYSYYNNSAEE 393
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L CR PEP I W G+ + S E + + L++ + G
Sbjct: 255 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWS--LEVEDAVVADSGE 312
Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
+ A+N+ G A + I + PP ++ L + V ++ +VV + P I
Sbjct: 313 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHI 372
Query: 767 TWCKNNKPVKALP-------------TKSD----------GDTHSITILKPKKVKDEGVY 803
W + NK + T+ D GD ++TI + D+G+Y
Sbjct: 373 IWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFN-VSLDDQGIY 431
Query: 804 TLKAENSEGIAETSAVITVEE 824
+ NS G++ +A +TV E
Sbjct: 432 ACLSGNSLGMSMANATLTVNE 452
Score = 37.5 bits (83), Expect = 0.10
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1260 EDDQCEYTC---VLLDAKSTTKLKVEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDY 1311
ED++ +Y+ V DA T+L + E P IV + + + G + L
Sbjct: 206 EDEEEDYSVSQPVAPDA-GLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRA 264
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHA 1369
+ +P+P W N K++KK + K SL ++ D+G + N G A
Sbjct: 265 KGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSA 324
Query: 1370 DVEMNVTILDKPSPPG--KPNILEIDSSSIN 1398
+V I+++ P PNIL S +IN
Sbjct: 325 KKYFHVIIVNRMRRPPIIVPNILANQSVNIN 355
Score = 34.3 bits (75), Expect = 0.97
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++F+CQ + W+R ++K Q D D+N L ++ + D G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 582 TCVAKNAAGFASSTTELIVEAPL 604
+C NA G S + V PL
Sbjct: 108 SCRVHNAYGQISRNFTVEVIDPL 130
Score = 34.3 bits (75), Expect = 0.97
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1320 EWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
EW N K++K + K I D+ L +K ++ +D G++ R+ N G V +
Sbjct: 67 EWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEV 126
Query: 1378 LD 1379
+D
Sbjct: 127 ID 128
>Z81017-7|CAB02673.2| 1040|Caenorhabditis elegans Hypothetical
protein F58A3.2a protein.
Length = 1040
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
P G T++ C+ +GYP PQI W++ ++K S Y+ N +L + + D+G
Sbjct: 305 PAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 581 FTCVAKNAAGFASSTTELIV 600
F C A N G A +I+
Sbjct: 365 FHCEALNKVGSAKKYFHVII 384
Score = 46.0 bits (104), Expect = 3e-04
Identities = 52/201 (25%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYT 804
G ++ L+ + G P P I W KN K +K +S G ++ V D G +
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 366
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPS 863
+A N G A+ + + PP+ + N +V T +V + +P
Sbjct: 367 CEALNKVGSAKKYFHVII---VNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 864 ITWYRNNEI--------ISPSE-----TITQNFD-------GENIELVITNVDSEIDSGD 903
I W R N+I S E T FD G+ L I NV + D G
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLD-DQGI 482
Query: 904 YKCVASNSAGKSSHGARVTID 924
Y C++ NS G S A +T++
Sbjct: 483 YACLSGNSLGMSMANATLTVN 503
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K K +E Y++ + T IT EEP + + + F E G T+K
Sbjct: 254 KENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVL--FNETHALPAGRTLK 311
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASN 910
L R P P I WY+N +++ S + ++ + + D+ + DSG++ C A N
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALN 371
Query: 911 SAGKSSHGARVTI 923
G + V I
Sbjct: 372 KVGSAKKYFHVII 384
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE---NRXXXXXXXXXXXXXXXYKCIA 1552
++L C G P+P++ WY++GK LK + A YE NR + C A
Sbjct: 310 LKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEA 369
Query: 1553 FNDHGEVET---SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
N G + +V ++P I + N Q + D + P +IW +
Sbjct: 370 LNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRI 429
Query: 1610 GNKLENDKEYNITTKEK 1626
NK+ Y + E+
Sbjct: 430 -NKINGSYSYYNNSAEE 445
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L CR PEP I W G+ + S E + + L++ + G
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWS--LEVEDAVVADSGE 364
Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
+ A+N+ G A + I + PP ++ L + V ++ +VV + P I
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHI 424
Query: 767 TWCKNNKPVKALP-------------TKSD----------GDTHSITILKPKKVKDEGVY 803
W + NK + T+ D GD ++TI + D+G+Y
Sbjct: 425 IWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFN-VSLDDQGIY 483
Query: 804 TLKAENSEGIAETSAVITVEE 824
+ NS G++ +A +TV E
Sbjct: 484 ACLSGNSLGMSMANATLTVNE 504
Score = 37.5 bits (83), Expect = 0.10
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1260 EDDQCEYTC---VLLDAKSTTKLKVEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDY 1311
ED++ +Y+ V DA T+L + E P IV + + + G + L
Sbjct: 258 EDEEEDYSVSQPVAPDA-GLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRA 316
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHA 1369
+ +P+P W N K++KK + K SL ++ D+G + N G A
Sbjct: 317 KGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSA 376
Query: 1370 DVEMNVTILDKPSPPG--KPNILEIDSSSIN 1398
+V I+++ P PNIL S +IN
Sbjct: 377 KKYFHVIIVNRMRRPPIIVPNILANQSVNIN 407
Score = 34.3 bits (75), Expect = 0.97
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1320 EWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
EW N K++K + K I D+ L +K ++ +D G++ R+ N G V +
Sbjct: 67 EWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEV 126
Query: 1378 LD 1379
+D
Sbjct: 127 ID 128
Score = 33.1 bits (72), Expect = 2.2
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++F+CQ + W+R ++K Q D D+N L ++ + D G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 582 TCVAKNAAGFASS--TTELI 599
+C NA G S T E+I
Sbjct: 108 SCRVHNAYGQISRNFTVEVI 127
>Z70680-10|CAA94577.2| 1208|Caenorhabditis elegans Hypothetical
protein C25G4.10 protein.
Length = 1208
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
T PS P N +SE T+ SVT++WTEP SN + NY + + K + + TV +
Sbjct: 265 THPSAPGNVTISELTAHSVTVQWTEPNSN-AHLVENYTLFIR--KNEHGEAVRTVKNVIS 321
Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
H + E + + + + G SLP+ ++
Sbjct: 322 PHVELGLDPDSEYVLTLQSHSANGTSLPSTAK 353
Score = 31.5 bits (68), Expect = 6.8
Identities = 23/109 (21%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTS 1439
PS PG I E+ + S+ + W EP N+ + Y + ++ + E + +VKN+
Sbjct: 267 PSAPGNVTISELTAHSVTVQWTEP-NSNAHLVENYTLFIRKNEHGEAVRTVKNVISPHVE 325
Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
+ L +S Y + + + + T + + + T+ T+ +P+
Sbjct: 326 L-GLDPDSEYVLTLQS-HSANGTSLPSTAKLFSTLPTTRPPLCTIGEPI 372
Score = 31.5 bits (68), Expect = 6.8
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 8/132 (6%)
Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY--QEIDTTE---WISVKNI 1433
D+P P K I +N+ WD N+ ++ +EY +DT + W +++
Sbjct: 602 DRPVAPEKLRISWNSGPRVNVTWDPVSVRRNAEVVTKPIEYTIYYLDTEQSSTWTTLRT- 660
Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNI 1491
+T +++L+ ++ Y A + S +S + PT +E K+
Sbjct: 661 NQTWVVMRDLRKDALYYVYVTAKEDNRTSRSSSIITILAQKDSPGLPEPTIVIEPDHKDG 720
Query: 1492 TTEPNEDIELTC 1503
P E I + C
Sbjct: 721 VFSPGEKISINC 732
>U39761-1|AAC46934.1| 1040|Caenorhabditis elegans EGL-15 protein.
Length = 1040
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
P G T++ C+ +GYP PQI W++ ++K S Y+ N +L + + D+G
Sbjct: 305 PAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 581 FTCVAKNAAGFASSTTELIV 600
F C A N G A +I+
Sbjct: 365 FHCEALNKVGSAKKYFHVII 384
Score = 46.0 bits (104), Expect = 3e-04
Identities = 52/201 (25%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYT 804
G ++ L+ + G P P I W KN K +K +S G ++ V D G +
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 366
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPS 863
+A N G A+ + + PP+ + N +V T +V + +P
Sbjct: 367 CEALNKVGSAKKYFHVII---VNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 864 ITWYRNNEI--------ISPSE-----TITQNFD-------GENIELVITNVDSEIDSGD 903
I W R N+I S E T FD G+ L I NV + D G
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLD-DQGI 482
Query: 904 YKCVASNSAGKSSHGARVTID 924
Y C++ NS G S A +T++
Sbjct: 483 YACLSGNSLGMSMANATLTVN 503
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K K +E Y++ + T IT EEP + + + F E G T+K
Sbjct: 254 KENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVL--FNETHALPAGRTLK 311
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASN 910
L R P P I WY+N +++ S + ++ + + D+ + DSG++ C A N
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALN 371
Query: 911 SAGKSSHGARVTI 923
G + V I
Sbjct: 372 KVGSAKKYFHVII 384
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE---NRXXXXXXXXXXXXXXXYKCIA 1552
++L C G P+P++ WY++GK LK + A YE NR + C A
Sbjct: 310 LKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEA 369
Query: 1553 FNDHGEVET---SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
N G + +V ++P I + N Q + D + P +IW +
Sbjct: 370 LNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRI 429
Query: 1610 GNKLENDKEYNITTKEK 1626
NK+ Y + E+
Sbjct: 430 -NKINGSYSYYNNSAEE 445
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L CR PEP I W G+ + S E + + L++ + G
Sbjct: 307 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWS--LEVEDAVVADSGE 364
Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
+ A+N+ G A + I + PP ++ L + V ++ +VV + P I
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHI 424
Query: 767 TWCKNNKPVKALP-------------TKSD----------GDTHSITILKPKKVKDEGVY 803
W + NK + T+ D GD ++TI + D+G+Y
Sbjct: 425 IWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFN-VSLDDQGIY 483
Query: 804 TLKAENSEGIAETSAVITVEE 824
+ NS G++ +A +TV E
Sbjct: 484 ACLSGNSLGMSMANATLTVNE 504
Score = 37.5 bits (83), Expect = 0.10
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1260 EDDQCEYTC---VLLDAKSTTKLKVEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDY 1311
ED++ +Y+ V DA T+L + E P IV + + + G + L
Sbjct: 258 EDEEEDYSVSQPVAPDA-GLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRA 316
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHA 1369
+ +P+P W N K++KK + K SL ++ D+G + N G A
Sbjct: 317 KGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSA 376
Query: 1370 DVEMNVTILDKPSPPG--KPNILEIDSSSIN 1398
+V I+++ P PNIL S +IN
Sbjct: 377 KKYFHVIIVNRMRRPPIIVPNILANQSVNIN 407
Score = 34.3 bits (75), Expect = 0.97
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1320 EWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
EW N K++K + K I D+ L +K ++ +D G++ R+ N G V +
Sbjct: 67 EWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEV 126
Query: 1378 LD 1379
+D
Sbjct: 127 ID 128
Score = 33.1 bits (72), Expect = 2.2
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++F+CQ + W+R ++K Q D D+N L ++ + D G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 582 TCVAKNAAGFASS--TTELI 599
+C NA G S T E+I
Sbjct: 108 SCRVHNAYGQISRNFTVEVI 127
>AY288941-1|AAP44084.1| 987|Caenorhabditis elegans EGL-15 protein.
Length = 987
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
P G T++ C+ +GYP PQI W++ ++K S Y+ N +L + + D+G
Sbjct: 252 PAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 311
Query: 581 FTCVAKNAAGFASSTTELIV 600
F C A N G A +I+
Sbjct: 312 FHCEALNKVGSAKKYFHVII 331
Score = 46.0 bits (104), Expect = 3e-04
Identities = 52/201 (25%), Positives = 79/201 (39%), Gaps = 29/201 (14%)
Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYT 804
G ++ L+ + G P P I W KN K +K +S G ++ V D G +
Sbjct: 254 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 313
Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPS 863
+A N G A+ + + PP+ + N +V T +V + +P
Sbjct: 314 CEALNKVGSAKKYFHVII---VNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPH 370
Query: 864 ITWYRNNEI--------ISPSE-----TITQNFD-------GENIELVITNVDSEIDSGD 903
I W R N+I S E T FD G+ L I NV + D G
Sbjct: 371 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLD-DQGI 429
Query: 904 YKCVASNSAGKSSHGARVTID 924
Y C++ NS G S A +T++
Sbjct: 430 YACLSGNSLGMSMANATLTVN 450
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K K +E Y++ + T IT EEP + + + F E G T+K
Sbjct: 201 KENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVL--FNETHALPAGRTLK 258
Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASN 910
L R P P I WY+N +++ S + ++ + + D+ + DSG++ C A N
Sbjct: 259 LNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALN 318
Query: 911 SAGKSSHGARVTI 923
G + V I
Sbjct: 319 KVGSAKKYFHVII 331
Score = 43.6 bits (98), Expect = 0.002
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)
Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE---NRXXXXXXXXXXXXXXXYKCIA 1552
++L C G P+P++ WY++GK LK + A YE NR + C A
Sbjct: 257 LKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEA 316
Query: 1553 FNDHGEVET---SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
N G + +V ++P I + N Q + D + P +IW +
Sbjct: 317 LNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRI 376
Query: 1610 GNKLENDKEYNITTKEK 1626
NK+ Y + E+
Sbjct: 377 -NKINGSYSYYNNSAEE 392
Score = 41.5 bits (93), Expect = 0.006
Identities = 46/201 (22%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L CR PEP I W G+ + S E + + L++ + G
Sbjct: 254 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWS--LEVEDAVVADSGE 311
Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
+ A+N+ G A + I + PP ++ L + V ++ +VV + P I
Sbjct: 312 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHI 371
Query: 767 TWCKNNKPVKALP-------------TKSD----------GDTHSITILKPKKVKDEGVY 803
W + NK + T+ D GD ++TI + D+G+Y
Sbjct: 372 IWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFN-VSLDDQGIY 430
Query: 804 TLKAENSEGIAETSAVITVEE 824
+ NS G++ +A +TV E
Sbjct: 431 ACLSGNSLGMSMANATLTVNE 451
Score = 37.5 bits (83), Expect = 0.10
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 13/151 (8%)
Query: 1260 EDDQCEYTC---VLLDAKSTTKLKVEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDY 1311
ED++ +Y+ V DA T+L + E P IV + + + G + L
Sbjct: 205 EDEEEDYSVSQPVAPDA-GLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRA 263
Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHA 1369
+ +P+P W N K++KK + K SL ++ D+G + N G A
Sbjct: 264 KGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSA 323
Query: 1370 DVEMNVTILDKPSPPG--KPNILEIDSSSIN 1398
+V I+++ P PNIL S +IN
Sbjct: 324 KKYFHVIIVNRMRRPPIIVPNILANQSVNIN 354
Score = 34.3 bits (75), Expect = 0.97
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1320 EWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
EW N K++K + K I D+ L +K ++ +D G++ R+ N G V +
Sbjct: 67 EWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEV 126
Query: 1378 LD 1379
+D
Sbjct: 127 ID 128
Score = 33.9 bits (74), Expect = 1.3
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++F+CQ + W+R ++K Q D D+N L ++ + D G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 582 TCVAKNAAG-FASSTTELIVEAPLSDHGSEMTV 613
+C NA G + + T +++ L D +E V
Sbjct: 108 SCRVHNAYGQISRNFTVEVIDPKLFDWLTEHRV 140
>U49941-8|AAB53876.1| 2427|Caenorhabditis elegans Spectrin protein 1
protein.
Length = 2427
Score = 49.6 bits (113), Expect = 2e-05
Identities = 22/71 (30%), Positives = 45/71 (63%), Gaps = 4/71 (5%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL--MDEN 478
D V A+Y Y ++ +++ +G+ L +L+ SN+DWW V+ + + +G+VPA Y+ ++
Sbjct: 986 DCVLALYDYQEKSPREVSMKKGDVLTLLNASNRDWWKVE--VNDRQGFVPAAYVKRIEPG 1043
Query: 479 NYTQYLQKKLN 489
Q+ Q+++N
Sbjct: 1044 TAQQHAQQQVN 1054
>AL032639-10|CAA21634.1| 108|Caenorhabditis elegans Hypothetical
protein Y38F1A.9 protein.
Length = 108
Score = 49.6 bits (113), Expect = 2e-05
Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
+ P F K P +GS +L EC A P+P + W K +E+ D +S I+ + +
Sbjct: 3 LAPFFEKAPSLIIAPDGS-VLFECICNANPQPTVKWFLKDKELTGDRYVS-KIKKMVGKF 60
Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASL 721
L I N + +G Y V A N G S+
Sbjct: 61 TVTLHIKNPTQEDQGVYKVTATNTHGSHSV 90
Score = 32.3 bits (70), Expect = 3.9
Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 3/94 (3%)
Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD--DDNV 565
+AP F + PDGS V FEC P+P + WF + + +
Sbjct: 3 LAPFFEKAPSLIIAPDGS-VLFECICNANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFT 61
Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
TL I+ ED G + A N G S + I
Sbjct: 62 VTLHIKNPTQEDQGVYKVTATNTHGSHSVEQQYI 95
Score = 32.3 bits (70), Expect = 3.9
Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITI-LK 793
E S+I+ SV+ NP+PT+ W +K + K ++T+ +K
Sbjct: 8 EKAPSLIIAPDGSVLFECICNANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFTVTLHIK 67
Query: 794 PKKVKDEGVYTLKAENSEG 812
+D+GVY + A N+ G
Sbjct: 68 NPTQEDQGVYKVTATNTHG 86
Score = 31.1 bits (67), Expect = 9.0
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK---EKTSVIRIKELKRSHSSKYTIEA 1647
L + P P V W+ +L D+ + K + T + IK + Y + A
Sbjct: 22 LFECICNANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFTVTLHIKNPTQEDQGVYKVTA 81
Query: 1648 SNTAGTSSVE 1657
+NT G+ SVE
Sbjct: 82 TNTHGSHSVE 91
Score = 31.1 bits (67), Expect = 9.0
Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 1313 AFPQPNDEWIVNSKIIKKCKHT---KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
A PQP +W + K + ++ K + + +L IK D G+YK+ N G
Sbjct: 29 ANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFTVTLHIKNPTQEDQGVYKVTATNTHGSH 88
Query: 1370 DVE 1372
VE
Sbjct: 89 SVE 91
>Z81479-9|CAB03937.1| 1117|Caenorhabditis elegans Hypothetical protein
C34F6.10 protein.
Length = 1117
Score = 48.8 bits (111), Expect = 4e-05
Identities = 65/302 (21%), Positives = 119/302 (39%), Gaps = 27/302 (8%)
Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP--VIMREI 1678
+TTK K V+ + +S T+ + T G S L++ KP P V + ++
Sbjct: 706 VTTKAKNIVLDSVQPGEKYS--VTLISLTTVGKSKQRTELEINVPALKPSAPEDVAVSQV 763
Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIE---KHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
+ T+ W + G + Y + E + ++ ++ + + + ++ L+ N
Sbjct: 764 QIDRCTVSWTAA-EGNGSPIIGYVVRMMLNGELFSEHFVTESENETNYR-HVLKYLDPNT 821
Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
EY+ + A+N VGFSE +E+ V+KT VP + ++ I W
Sbjct: 822 EYLINIAAKNSVGFSEKIEA---VVKT---VPLCPTIPKIWCDCEATALKIHW--DRVTS 873
Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE-IGTSLPYTSD 1854
G+ ++ YK+ + + A+++ L NT Y F++ + G S T
Sbjct: 874 GNSMM-YKLMKINKNAQQVTLYEGENNTAKVKSLKENTKYVFKLRVSDRATGAS---TWS 929
Query: 1855 DKITIGKTLTPP----SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
+ + T PP P +VS S ++W + I TVKG
Sbjct: 930 ESFSFSTTTAPPPPLKKSPSTALVS-GHSYLYRIEWENCLPDSSQHYYRLQIADATVKGA 988
Query: 1911 SW 1912
W
Sbjct: 989 KW 990
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/141 (26%), Positives = 63/141 (44%), Gaps = 14/141 (9%)
Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
Y + + +G S T ++ I PS P + VS+ T+ WT E NG
Sbjct: 724 YSVTLISLTTVGKSKQRT---ELEINVPALKPSAPEDVAVSQVQIDRCTVSWTAAEGNG- 779
Query: 1895 SPITNYIIEFKTVKGKSWTK-IVTVGGSV--HEHCIENIKEKDEIIFRISAENTVGVSLP 1951
SPI Y++ + G+ +++ VT + + H ++ + E + I+A+N+VG S
Sbjct: 780 SPIIGYVVRMM-LNGELFSEHFVTESENETNYRHVLKYLDPNTEYLINIAAKNSVGFSEK 838
Query: 1952 TESQSVRLEKHATVPSPPTAP 1972
E+ TVP PT P
Sbjct: 839 IEAVV------KTVPLCPTIP 853
Score = 40.3 bits (90), Expect = 0.015
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 16/185 (8%)
Query: 1666 PSKPEGPVIMREISRESVTIE--WKPPLDDGGLELTKYAIEKHEPD--NNRWIKVADVDR 1721
P +PE P + +SR IE WK +++G ++ Y + HE + + R ++ A+
Sbjct: 257 PGRPEPPTEVEILSRGLHFIELVWKTAINNGAF-ISHYHVYIHENELEDGRMMQTAE--- 312
Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
E I L Y R+ + N +G E++E + + T + P +
Sbjct: 313 --EKIQISNLIPQTCYKIRIHSINALG--ESMEGYELDVWTKPNSPPLAPENISVFAQSH 368
Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
S+ ++W +KN I +V GK I +L +T YQ R+ A
Sbjct: 369 RSIRVSW---DKNPNCTIW-IEVYNCASGKGGYARENFGGDQTVIGELDPDTEYQMRVIA 424
Query: 1842 RNEIG 1846
RNE G
Sbjct: 425 RNEFG 429
Score = 37.9 bits (84), Expect = 0.078
Identities = 42/175 (24%), Positives = 67/175 (38%), Gaps = 10/175 (5%)
Query: 1794 NGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853
N G+ I Y V I + + +I L T Y+ RI++ N +G S+
Sbjct: 285 NNGAFISHYHVYIHENELEDGRMMQTAEEKIQISNLIPQTCYKIRIHSINALGESMEGYE 344
Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
D T K +PP P N V + RS+ + W + + T +I + GK
Sbjct: 345 LDVWT--KPNSPPLAPENISVFAQSHRSIRVSWDKNPN-----CTIWIEVYNCASGKGGY 397
Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
GG + I + E R+ A N G +E ++R +K+ P
Sbjct: 398 ARENFGGD--QTVIGELDPDTEYQMRVIARNEFGEG-HSEYINMRTQKYRKSEHP 449
Score = 37.5 bits (83), Expect = 0.10
Identities = 31/115 (26%), Positives = 58/115 (50%), Gaps = 9/115 (7%)
Query: 1948 VSLPTESQSV-RLEKHATVPS-PPTAPLEIRMVGSNI--VMTSWGTPEWDGGAPLLGYNI 2003
+SL T +S R E VP+ P+AP ++ + I SW E +G +P++GY +
Sbjct: 729 ISLTTVGKSKQRTELEINVPALKPSAPEDVAVSQVQIDRCTVSWTAAEGNG-SPIIGYVV 787
Query: 2004 AIR---DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
+ ++ ++ + + N + ++ L N Y+I I A+N +G SE +E+
Sbjct: 788 RMMLNGELFSEHFVTESENETN-YRHVLKYLDPNTEYLINIAAKNSVGFSEKIEA 841
Score = 34.3 bits (75), Expect = 0.97
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 6/101 (5%)
Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTE 1426
++E+NV L KPS P + ++ + W E G S II YVV E+ +
Sbjct: 742 ELEINVPAL-KPSAPEDVAVSQVQIDRCTVSWTAAEGNG-SPIIGYVVRMMLNGELFSEH 799
Query: 1427 WIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
+++ +N T + ++ L N+ Y A N V S+ E
Sbjct: 800 FVTESENETNYRHVLKYLDPNTEYLINIAAKNSVGFSEKIE 840
Score = 32.3 bits (70), Expect = 3.9
Identities = 27/123 (21%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
+P PP + IL I + W N G + I +Y V E + + + + +
Sbjct: 259 RPEPPTEVEILSRGLHFIELVWKTAINNG-AFISHYHVYIHENELEDG-RMMQTAEEKIQ 316
Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
I NL + Y+ R +++N + E+ E Y++ TK SP + ++ + + I
Sbjct: 317 ISNLIPQTCYKIRIHSINAL-----GESMEGYELDVWTKPNSPPLAPENISVFAQSHRSI 371
Query: 1500 ELT 1502
++
Sbjct: 372 RVS 374
>AC084152-8|AAK39317.1| 541|Caenorhabditis elegans Hypothetical
protein Y102A11A.8 protein.
Length = 541
Score = 48.0 bits (109), Expect = 7e-05
Identities = 40/159 (25%), Positives = 78/159 (49%), Gaps = 19/159 (11%)
Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
W KNG +L+ D +Y ++ K +++K +K S +Y +A+N G ++E + V+D+
Sbjct: 70 WSKNGEQLDWDSQYKLSKDSKE--LKMKSVKFEDSGRYQCQATNGFGHKTIEFIVHVHDQ 127
Query: 1666 PSKPEGP----VIMREISRESVTI----EWKPP--LDDGG-LELTKYAIEKHEPDNNRW- 1713
K V+ + S I EW+ P ++ GG LEL A P+ RW
Sbjct: 128 HDKENSVKDYLVLSNTTASPSWLIDMNSEWRSPIKINTGGKLELRCPAQGNPLPE-IRWY 186
Query: 1714 ---IKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
+++++ + V T ++ + + ++R + +NP+G
Sbjct: 187 QNEMEISEKTHKHVSTITVEPVESSHSGVYRCVVENPLG 225
Score = 37.9 bits (84), Expect = 0.078
Identities = 15/55 (27%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
I K +++W K+G ++ + + +L+ D K+ K+K +D+G Y C+ N
Sbjct: 59 IATEKDSTMIQWSKNGEQLDWDSQYKLSKDSKELKMK--SVKFEDSGRYQCQATN 111
Score = 37.5 bits (83), Expect = 0.10
Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 11/124 (8%)
Query: 1287 PPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
P ++D E+R I G + L Q P P W N I + H S
Sbjct: 147 PSWLIDMNSEWRSPIKINTGGKLELRCPAQGNPLPEIRWYQNEMEISEKTHKHVS----- 201
Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
++T++ VE++ +G+Y+ +EN G +V++ D P E +++ D
Sbjct: 202 -TITVEPVESSHSGVYRCVVENPLGSLSFAFDVSVGDF-FDPTTTEATEYQETAMEPVID 259
Query: 1403 EPEN 1406
+P N
Sbjct: 260 QPYN 263
Score = 36.3 bits (80), Expect = 0.24
Identities = 45/176 (25%), Positives = 71/176 (40%), Gaps = 26/176 (14%)
Query: 766 ITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV-E 823
I W KN + + K D+ + +K K +D G Y +A N G ++ V +
Sbjct: 68 IQWSKNGEQLDWDSQYKLSKDSKELK-MKSVKFEDSGRYQCQATNGFGHKTIEFIVHVHD 126
Query: 824 EPTEEN------------AEPPLFINRFQE----ITVKEKGTIKLVARVTRNPVPSITWY 867
+ +EN A P I+ E I + G ++L NP+P I WY
Sbjct: 127 QHDKENSVKDYLVLSNTTASPSWLIDMNSEWRSPIKINTGGKLELRCPAQGNPLPEIRWY 186
Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
+N I SE ++ +E V ++ SG Y+CV N G S V++
Sbjct: 187 QNEMEI--SEKTHKHVSTITVEPVESS-----HSGVYRCVVENPLGSLSFAFDVSV 235
Score = 35.1 bits (77), Expect = 0.55
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
+G P PE+ WY +N+ E + T + S I ++ ++ SHS Y N G+ S
Sbjct: 176 QGNPLPEIRWY------QNEMEISEKTHKHVSTITVEPVESSHSGVYRCVVENPLGSLSF 229
Query: 1657 EVTLKVYD 1664
+ V D
Sbjct: 230 AFDVSVGD 237
Score = 34.7 bits (76), Expect = 0.73
Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND---EWIVNSKIIKKCKHTKPSIDSKSA 1343
PP++ + E ++RI G LV + + +W N + + K S DSK
Sbjct: 33 PPRMRNVETKFRIPLGQKQFRLVCPIIATEKDSTMIQWSKNGEQLDWDSQYKLSKDSKE- 91
Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
L +K V+ D+G Y+ + N GH +E V + D+
Sbjct: 92 -LKMKSVKFEDSGRYQCQATNGFGHKTIEFIVHVHDQ 127
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 7/77 (9%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G ++ C +G P P+I W++ I +V+T+ + V +G + C
Sbjct: 166 GGKLELRCPAQGNPLPEIRWYQNEMEISEK-------THKHVSTITVEPVESSHSGVYRC 218
Query: 584 VAKNAAGFASSTTELIV 600
V +N G S ++ V
Sbjct: 219 VVENPLGSLSFAFDVSV 235
Score = 31.1 bits (67), Expect = 9.0
Identities = 41/169 (24%), Positives = 74/169 (43%), Gaps = 23/169 (13%)
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
+ G + L GNP P I W +N + K+ +IT+ +P + GVY
Sbjct: 163 INTGGKLELRCPAQGNPLPEIRWYQNEMEIS---EKTHKHVSTITV-EPVESSHSGVYRC 218
Query: 806 KAENSEGIAETSAVITVE---EPT-------EENAEPPLFINRFQEITVKEKGTIKLVAR 855
EN G + ++V +PT +E A P+ I++ I+V T + +
Sbjct: 219 VVENPLGSLSFAFDVSVGDFFDPTTTEATEYQETAMEPV-IDQPYNISVYAGHTAQFQCK 277
Query: 856 VTRNPVPSITWYRN-NEIIS-----PSETITQNFDGENIELVITNVDSE 898
V N I W + ++ +S P+ T+ + +G N+ LV+ ++ +E
Sbjct: 278 VKSNENTIIKWLKEVSDPLSIRRKDPNSTVI-HVNGMNL-LVLDHIQTE 324
>AL022270-1|CAB63432.1| 1270|Caenorhabditis elegans Hypothetical
protein C26G2.1 protein.
Length = 1270
Score = 47.6 bits (108), Expect = 1e-04
Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 14/179 (7%)
Query: 1486 KPLKNITTEPNEDIELTCIFGGV-PQPKVTWYRDGKKL----KTAKATYENRXXXXXXXX 1540
+P I + N + +TC+ V P+P+V WY DGK + K A + N+
Sbjct: 135 QPNSIIAVKENTPLNITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSL 194
Query: 1541 XXXXXXX-----YKCIAFNDHGEVE--TSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLV 1592
C AF ++ T+ + + P T+ + GD +
Sbjct: 195 VVQSDRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEILRNPSALRSGDNVTI 254
Query: 1593 T-AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
+V G PPP+V WY +L++ + +KE ++ + + ++Y A+N+
Sbjct: 255 ACSVTGGNPPPDVFWYHENKRLQSHSTLDTRSKEIKNIYSFIASQNDNMAEYECRANNS 313
Score = 44.4 bits (100), Expect = 0.001
Identities = 83/399 (20%), Positives = 159/399 (39%), Gaps = 40/399 (10%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-----EPLKSMIVRQG 749
LKIT+V +G Y ++ E PI K PPQ++ +P + V++
Sbjct: 89 LKITHVNLDDDGEYECQMLHPEEG---PIRAKSFLNIIVPPQLVYFSNYQPNSIIAVKEN 145
Query: 750 ESVILSAQVVG-NPRPTITWCKNNK----PVKALPTKSDGDTHSI--TILKPKKVKDEG- 801
+ ++ V P P + W + K VK T T ++ +++ D G
Sbjct: 146 TPLNITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQSDRNDHGK 205
Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR-NP 860
V T +A E + T++ + +P + I R ++ + + VT NP
Sbjct: 206 VITCEAFQKETDIRITTNTTLDVLFPPS-DPTVEILR-NPSALRSGDNVTIACSVTGGNP 263
Query: 861 VPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
P + WY N+ + T+ T++ + +NI I + + + +Y+C A+NS +
Sbjct: 264 PPDVFWYHENKRLQSHSTLDTRSKEIKNIYSFIASQNDNM--AEYECRANNSRTGNPKRK 321
Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVS-TKWYHNKKEISGMDHREII 976
+ ++V L G + ++C++ S+ S W N + + RE +
Sbjct: 322 AMKLEVNYPPASVELFGESNIRYGSSANIQCKSLPSNPASQITWIINGRSVPTPTQREFV 381
Query: 977 QEGRXXXXXXXXXXXXDVGV------IKCIVKDQETST--MLVVKETIP---EFIRKLQD 1025
E ++ V ++C+ + E S+ V+K P I L+D
Sbjct: 382 VENGIVSSSNVSVHSNELSVEAHQINVECMATNPEGSSAKQHVIKIIAPPKAPIITGLED 441
Query: 1026 FEVKEKDV--AILEVEINSETADVVWERDGE--IIKPKK 1060
+ E D+ E + + A++ W R E ++K +K
Sbjct: 442 RKFFEGDIVNVTCEAQGGNPLAELSWYRGSEKHLVKGRK 480
Score = 42.3 bits (95), Expect = 0.004
Identities = 89/394 (22%), Positives = 156/394 (39%), Gaps = 44/394 (11%)
Query: 1163 LKIYDCDLDDAGEYSC-----EVGNSKCTAILTVEEPS--INFTLRLPEFIL-VPANTDA 1214
LKI +LDD GEY C E G + + L + P + F+ P I+ V NT
Sbjct: 89 LKITHVNLDDDGEYECQMLHPEEGPIRAKSFLNIIVPPQLVYFSNYQPNSIIAVKENTPL 148
Query: 1215 YLTVEIPD--ETLDVTWYKKKSVIEDTEKFTLISDVKK-----RTLIIRKCTEDDQCEYT 1267
+T +P+ +V WY V+ K + K +L+++ D T
Sbjct: 149 NITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQSDRNDHGKVIT 208
Query: 1268 CVLL----DAKSTTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQ-AFPQPND 1319
C D + TT ++V+ FPP E ++ G +VT+ P P+
Sbjct: 209 CEAFQKETDIRITTNTTLDVL-FPPSDPTVEILRNPSALRSGDNVTIACSVTGGNPPPDV 267
Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKV--ENTDAGIYKLRLENNCGHADVEMNVTI 1377
W +K ++ H+ SK + +N + Y+ R NN + +
Sbjct: 268 FWYHENKRLQ--SHSTLDTRSKEIKNIYSFIASQNDNMAEYECR-ANNSRTGNPKRKAMK 324
Query: 1378 LDKPSPP------GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT-TEWISV 1430
L+ PP G+ NI S++I C P N + I +++ + + T T+ V
Sbjct: 325 LEVNYPPASVELFGESNIRYGSSANIQ-CKSLPSNPASQ--ITWIINGRSVPTPTQREFV 381
Query: 1431 KNITKTQTSIQNLKTNSS-YRFRAYAVN-EVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
+ S N+ +S+ A+ +N E ++ ++ VIK + L
Sbjct: 382 --VENGIVSSSNVSVHSNELSVEAHQINVECMATNPEGSSAKQHVIKIIAPPKAPIITGL 439
Query: 1489 KNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKK 1521
++ + + +TC GG P +++WYR +K
Sbjct: 440 EDRKFFEGDIVNVTCEAQGGNPLAELSWYRGSEK 473
Score = 42.3 bits (95), Expect = 0.004
Identities = 49/189 (25%), Positives = 77/189 (40%), Gaps = 20/189 (10%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI-TWCKNNKPVKALPTKSDGDTHSITIL 792
P ++ ++++ +G+S + V GNP ++ W KN P + ++
Sbjct: 690 PKMLVNDPVTVVMSEGDSFKENLTVRGNPAISLWQWRKNGVPFDHTIGRVFA-RGAVLSG 748
Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIK 851
K D GVYTL A NS G S IT++ E +A I + G T+
Sbjct: 749 KQLLSTDAGVYTLTATNSVG----STNITIKLAVEYSAR----ITSISTPVIAATGDTVL 800
Query: 852 LVARVTRNPVPS--ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
L P + I WY+N EI++ G ++ N +E SG+Y C A
Sbjct: 801 LECEADGEPSKANMIHWYKNGEILAAQHR------GHKKAILRLNA-TEQQSGEYTCKAD 853
Query: 910 NSAGKSSHG 918
N G + G
Sbjct: 854 NGIGVPAEG 862
Score = 39.5 bits (88), Expect = 0.026
Identities = 64/291 (21%), Positives = 113/291 (38%), Gaps = 24/291 (8%)
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
P + +N + + E + K V NP S+ +R N + TI + F L
Sbjct: 690 PKMLVNDPVTVVMSEGDSFKENLTVRGNPAISLWQWRKNGVPF-DHTIGRVF-ARGAVLS 747
Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
+ S D+G Y A+NS G ++ + + VE + + G TV+LEC+
Sbjct: 748 GKQLLST-DAGVYTLTATNSVGSTN--ITIKLAVEYSARITSISTPVIAATGDTVLLECE 804
Query: 952 TSHTVSTK----WYHNKKEISGMDHR----EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
S WY N EI HR I++ D G+ + +
Sbjct: 805 ADGEPSKANMIHWYKNG-EILAAQHRGHKKAILRLNATEQQSGEYTCKADNGI--GVPAE 861
Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNK 1062
+T ++ + R + + VA ++ + T + VWE+D ++IK +K
Sbjct: 862 GQTFLLVNSAPRVLPVARYAKTAGILG-GVAKARCKVYAVPTVEFVWEKDEQLIKKNSSK 920
Query: 1063 Y-----DFEKRGHIRKLYIRNTSVHD-EGEYSCILRDESCTAEVTVVELPP 1107
Y + + L+I+N D + CI R+ T +++ +PP
Sbjct: 921 YSIVNTQIDYSTYESTLWIKNIVPDDYTKKVKCIARNSFGTDHLSIPIIPP 971
Score = 32.3 bits (70), Expect = 3.9
Identities = 38/200 (19%), Positives = 68/200 (34%), Gaps = 12/200 (6%)
Query: 1482 PTVEKPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXX 1536
PTVE +++ + C + GG P P V WY + K+L++ + E +
Sbjct: 235 PTVEILRNPSALRSGDNVTIACSVTGGNPPPDVFWYHENKRLQSHSTLDTRSKEIKNIYS 294
Query: 1537 XXXXXXXXXXXYKCIAFNDH-GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
Y+C A N G + + P ++ +
Sbjct: 295 FIASQNDNMAEYECRANNSRTGNPKRKAMKLEVNYPPASVELFGESNIRYGSSANIQCKS 354
Query: 1596 IEGIPPPEVIWYKNGNKL------ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
+ P ++ W NG + E E I + SV + +H A+N
Sbjct: 355 LPSNPASQITWIINGRSVPTPTQREFVVENGIVSSSNVSVHSNELSVEAHQINVECMATN 414
Query: 1650 TAGTSSVEVTLKVYDKPSKP 1669
G+S+ + +K+ P P
Sbjct: 415 PEGSSAKQHVIKIIAPPKAP 434
Score = 31.9 bits (69), Expect = 5.2
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 8/86 (9%)
Query: 1592 VTAVIEGIPP-PEVIWYKNGNKLEND-KEYNITTKEKTSVIR----IKELKRSHSSKYTI 1645
+T V+ + P PEV+WY +G + D K+ + KT + ++ + H T
Sbjct: 150 ITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQSDRNDHGKVITC 209
Query: 1646 EA--SNTAGTSSVEVTLKVYDKPSKP 1669
EA T + TL V PS P
Sbjct: 210 EAFQKETDIRITTNTTLDVLFPPSDP 235
Score = 31.5 bits (68), Expect = 6.8
Identities = 13/45 (28%), Positives = 27/45 (60%)
Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
HT + ++ A L+ K++ +TDAG+Y L N+ G ++ + + +
Sbjct: 734 HTIGRVFARGAVLSGKQLLSTDAGVYTLTATNSVGSTNITIKLAV 778
>AC024791-20|AAO12400.1| 574|Caenorhabditis elegans Hypothetical
protein Y47G6A.5b protein.
Length = 574
Score = 47.2 bits (107), Expect = 1e-04
Identities = 16/47 (34%), Positives = 34/47 (72%)
Query: 429 YVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLM 475
++A+T + +++ EG+ LY+++ SN++WWYV + KG+VP +++
Sbjct: 105 FLAQTPKEMSVEEGDVLYLIEQSNREWWYVASKSRQFKGFVPKSHVV 151
>AC024791-19|AAF60657.2| 618|Caenorhabditis elegans Hypothetical
protein Y47G6A.5a protein.
Length = 618
Score = 47.2 bits (107), Expect = 1e-04
Identities = 16/47 (34%), Positives = 34/47 (72%)
Query: 429 YVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLM 475
++A+T + +++ EG+ LY+++ SN++WWYV + KG+VP +++
Sbjct: 149 FLAQTPKEMSVEEGDVLYLIEQSNREWWYVASKSRQFKGFVPKSHVV 195
>Z47808-12|CAB61003.1| 902|Caenorhabditis elegans Hypothetical
protein C01G6.8b protein.
Length = 902
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/98 (29%), Positives = 43/98 (43%)
Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
Q+P I ++++ GDE G PP + IW KN +E K I KE +S
Sbjct: 8 QRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSS 67
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I +L S Y SN A + + L+V + P
Sbjct: 68 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVP 105
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
+LR G V+F+C+ G P + W + ++ ++ ++ D +N + LVI ++
Sbjct: 17 QLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIR-DKENSSRLVITQLD 75
Query: 575 PEDAGTFTCVAKNAAGFASSTTELIV 600
D+G + C+ N A ++T+ L V
Sbjct: 76 VLDSGYYQCIVSNPAASVNTTSVLRV 101
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDT 786
TG++ ++ L++ G+ V + +G P W KNN PV K K D +
Sbjct: 6 TGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKEN 65
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S ++ V D G Y N T++V+ V
Sbjct: 66 SSRLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRV 101
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
++ + T ++ P W +NN + ++ + + LVIT +D
Sbjct: 16 SQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLD 75
Query: 897 SEIDSGDYKCVASNSA 912
+DSG Y+C+ SN A
Sbjct: 76 V-LDSGYYQCIVSNPA 90
Score = 32.3 bits (70), Expect = 3.9
Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
+ ++L+N + G++ F+ E L W K+ ++ + +++ +L I
Sbjct: 14 LTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQ 73
Query: 1168 CDLDDAGEYSCEVGN 1182
D+ D+G Y C V N
Sbjct: 74 LDVLDSGYYQCIVSN 88
Score = 31.9 bits (69), Expect = 5.2
Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 4/88 (4%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAK-ATYENRXXXXXXXXXXX 1543
L+N T +++ C G P K W ++ +K K K EN
Sbjct: 18 LRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVL 77
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
Y+CI N V T+ V+ + P
Sbjct: 78 DSGYYQCIVSNPAASVNTTSVLRVNNVP 105
>Z47808-11|CAD36487.1| 928|Caenorhabditis elegans Hypothetical
protein C01G6.8a protein.
Length = 928
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/98 (29%), Positives = 43/98 (43%)
Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
Q+P I ++++ GDE G PP + IW KN +E K I KE +S
Sbjct: 34 QRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSS 93
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I +L S Y SN A + + L+V + P
Sbjct: 94 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVP 131
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
+LR G V+F+C+ G P + W + ++ ++ ++ D +N + LVI ++
Sbjct: 43 QLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIR-DKENSSRLVITQLD 101
Query: 575 PEDAGTFTCVAKNAAGFASSTTELIV 600
D+G + C+ N A ++T+ L V
Sbjct: 102 VLDSGYYQCIVSNPAASVNTTSVLRV 127
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDT 786
TG++ ++ L++ G+ V + +G P W KNN PV K K D +
Sbjct: 32 TGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKEN 91
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S ++ V D G Y N T++V+ V
Sbjct: 92 SSRLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRV 127
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
++ + T ++ P W +NN + ++ + + LVIT +D
Sbjct: 42 SQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLD 101
Query: 897 SEIDSGDYKCVASNSA 912
+DSG Y+C+ SN A
Sbjct: 102 V-LDSGYYQCIVSNPA 116
Score = 32.3 bits (70), Expect = 3.9
Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
+ ++L+N + G++ F+ E L W K+ ++ + +++ +L I
Sbjct: 40 LTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQ 99
Query: 1168 CDLDDAGEYSCEVGN 1182
D+ D+G Y C V N
Sbjct: 100 LDVLDSGYYQCIVSN 114
Score = 31.9 bits (69), Expect = 5.2
Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 4/88 (4%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAK-ATYENRXXXXXXXXXXX 1543
L+N T +++ C G P K W ++ +K K K EN
Sbjct: 44 LRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVL 103
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
Y+CI N V T+ V+ + P
Sbjct: 104 DSGYYQCIVSNPAASVNTTSVLRVNNVP 131
>Z35595-13|CAA84639.2| 902|Caenorhabditis elegans Hypothetical
protein C01G6.8b protein.
Length = 902
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/98 (29%), Positives = 43/98 (43%)
Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
Q+P I ++++ GDE G PP + IW KN +E K I KE +S
Sbjct: 8 QRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSS 67
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I +L S Y SN A + + L+V + P
Sbjct: 68 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVP 105
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
+LR G V+F+C+ G P + W + ++ ++ ++ D +N + LVI ++
Sbjct: 17 QLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIR-DKENSSRLVITQLD 75
Query: 575 PEDAGTFTCVAKNAAGFASSTTELIV 600
D+G + C+ N A ++T+ L V
Sbjct: 76 VLDSGYYQCIVSNPAASVNTTSVLRV 101
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDT 786
TG++ ++ L++ G+ V + +G P W KNN PV K K D +
Sbjct: 6 TGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKEN 65
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S ++ V D G Y N T++V+ V
Sbjct: 66 SSRLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRV 101
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
++ + T ++ P W +NN + ++ + + LVIT +D
Sbjct: 16 SQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLD 75
Query: 897 SEIDSGDYKCVASNSA 912
+DSG Y+C+ SN A
Sbjct: 76 V-LDSGYYQCIVSNPA 90
Score = 32.3 bits (70), Expect = 3.9
Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
+ ++L+N + G++ F+ E L W K+ ++ + +++ +L I
Sbjct: 14 LTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQ 73
Query: 1168 CDLDDAGEYSCEVGN 1182
D+ D+G Y C V N
Sbjct: 74 LDVLDSGYYQCIVSN 88
Score = 31.9 bits (69), Expect = 5.2
Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 4/88 (4%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAK-ATYENRXXXXXXXXXXX 1543
L+N T +++ C G P K W ++ +K K K EN
Sbjct: 18 LRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVL 77
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
Y+CI N V T+ V+ + P
Sbjct: 78 DSGYYQCIVSNPAASVNTTSVLRVNNVP 105
>Z35595-12|CAD36478.1| 928|Caenorhabditis elegans Hypothetical
protein C01G6.8a protein.
Length = 928
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/98 (29%), Positives = 43/98 (43%)
Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
Q+P I ++++ GDE G PP + IW KN +E K I KE +S
Sbjct: 34 QRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSS 93
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I +L S Y SN A + + L+V + P
Sbjct: 94 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVP 131
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
+LR G V+F+C+ G P + W + ++ ++ ++ D +N + LVI ++
Sbjct: 43 QLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIR-DKENSSRLVITQLD 101
Query: 575 PEDAGTFTCVAKNAAGFASSTTELIV 600
D+G + C+ N A ++T+ L V
Sbjct: 102 VLDSGYYQCIVSNPAASVNTTSVLRV 127
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDT 786
TG++ ++ L++ G+ V + +G P W KNN PV K K D +
Sbjct: 32 TGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKEN 91
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S ++ V D G Y N T++V+ V
Sbjct: 92 SSRLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRV 127
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
++ + T ++ P W +NN + ++ + + LVIT +D
Sbjct: 42 SQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLD 101
Query: 897 SEIDSGDYKCVASNSA 912
+DSG Y+C+ SN A
Sbjct: 102 V-LDSGYYQCIVSNPA 116
Score = 32.3 bits (70), Expect = 3.9
Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
+ ++L+N + G++ F+ E L W K+ ++ + +++ +L I
Sbjct: 40 LTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQ 99
Query: 1168 CDLDDAGEYSCEVGN 1182
D+ D+G Y C V N
Sbjct: 100 LDVLDSGYYQCIVSN 114
Score = 31.9 bits (69), Expect = 5.2
Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 4/88 (4%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAK-ATYENRXXXXXXXXXXX 1543
L+N T +++ C G P K W ++ +K K K EN
Sbjct: 44 LRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVL 103
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
Y+CI N V T+ V+ + P
Sbjct: 104 DSGYYQCIVSNPAASVNTTSVLRVNNVP 131
>AJ132947-1|CAC29085.1| 902|Caenorhabditis elegans receptor tyrosine
kinase protein.
Length = 902
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/98 (29%), Positives = 43/98 (43%)
Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
Q+P I ++++ GDE G PP + IW KN +E K I KE +S
Sbjct: 8 QRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSS 67
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I +L S Y SN A + + L+V + P
Sbjct: 68 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVP 105
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
+LR G V+F+C+ G P + W + ++ ++ ++ D +N + LVI ++
Sbjct: 17 QLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIR-DKENSSRLVITQLD 75
Query: 575 PEDAGTFTCVAKNAAGFASSTTELIV 600
D+G + C+ N A ++T+ L V
Sbjct: 76 VLDSGYYQCIVSNPAASVNTTSVLRV 101
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDT 786
TG++ ++ L++ G+ V + +G P W KNN PV K K D +
Sbjct: 6 TGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKEN 65
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S ++ V D G Y N T++V+ V
Sbjct: 66 SSRLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRV 101
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
++ + T ++ P W +NN + ++ + + LVIT +D
Sbjct: 16 SQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLD 75
Query: 897 SEIDSGDYKCVASNSA 912
+DSG Y+C+ SN A
Sbjct: 76 V-LDSGYYQCIVSNPA 90
Score = 32.3 bits (70), Expect = 3.9
Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
+ ++L+N + G++ F+ E L W K+ ++ + +++ +L I
Sbjct: 14 LTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQ 73
Query: 1168 CDLDDAGEYSCEVGN 1182
D+ D+G Y C V N
Sbjct: 74 LDVLDSGYYQCIVSN 88
Score = 31.9 bits (69), Expect = 5.2
Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 4/88 (4%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAK-ATYENRXXXXXXXXXXX 1543
L+N T +++ C G P K W ++ +K K K EN
Sbjct: 18 LRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVL 77
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
Y+CI N V T+ V+ + P
Sbjct: 78 DSGYYQCIVSNPAASVNTTSVLRVNNVP 105
>AJ132946-1|CAC29084.1| 928|Caenorhabditis elegans receptor tyrosine
kinase protein.
Length = 928
Score = 46.8 bits (106), Expect = 2e-04
Identities = 29/98 (29%), Positives = 43/98 (43%)
Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
Q+P I ++++ GDE G PP + IW KN +E K I KE +S
Sbjct: 34 QRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSS 93
Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
+ I +L S Y SN A + + L+V + P
Sbjct: 94 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVP 131
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
+LR G V+F+C+ G P + W + ++ ++ ++ D +N + LVI ++
Sbjct: 43 QLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIR-DKENSSRLVITQLD 101
Query: 575 PEDAGTFTCVAKNAAGFASSTTELIV 600
D+G + C+ N A ++T+ L V
Sbjct: 102 VLDSGYYQCIVSNPAASVNTTSVLRV 127
Score = 38.3 bits (85), Expect = 0.059
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDT 786
TG++ ++ L++ G+ V + +G P W KNN PV K K D +
Sbjct: 32 TGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKEN 91
Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
S ++ V D G Y N T++V+ V
Sbjct: 92 SSRLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRV 127
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
++ + T ++ P W +NN + ++ + + LVIT +D
Sbjct: 42 SQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLD 101
Query: 897 SEIDSGDYKCVASNSA 912
+DSG Y+C+ SN A
Sbjct: 102 V-LDSGYYQCIVSNPA 116
Score = 32.3 bits (70), Expect = 3.9
Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
+ ++L+N + G++ F+ E L W K+ ++ + +++ +L I
Sbjct: 40 LTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQ 99
Query: 1168 CDLDDAGEYSCEVGN 1182
D+ D+G Y C V N
Sbjct: 100 LDVLDSGYYQCIVSN 114
Score = 31.9 bits (69), Expect = 5.2
Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 4/88 (4%)
Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAK-ATYENRXXXXXXXXXXX 1543
L+N T +++ C G P K W ++ +K K K EN
Sbjct: 44 LRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVL 103
Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
Y+CI N V T+ V+ + P
Sbjct: 104 DSGYYQCIVSNPAASVNTTSVLRVNNVP 131
>U49830-7|AAM98046.1| 774|Caenorhabditis elegans Neuronal igcam
protein 6, isoform c protein.
Length = 774
Score = 46.4 bits (105), Expect = 2e-04
Identities = 94/419 (22%), Positives = 163/419 (38%), Gaps = 47/419 (11%)
Query: 1095 SCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEI----- 1146
S EV V + PP I+ L ++ V + +FE L+ D+ V WFKD I
Sbjct: 6 SAAGEVHVKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLL 65
Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRL 1202
+L ID LK D D+G Y C +VG+S +A+LTV++ + F
Sbjct: 66 PAEKRKRLKIDHNVLHLKF--ADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFP--- 120
Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTE 1260
P + TV IP + K K ++ + I K
Sbjct: 121 PNAMSRKVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKGRIRDEEGVISIEKVLH 180
Query: 1261 DDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA-FPQP 1317
+D + C + K+ ++++ VV P ++ E + +V L + A P+
Sbjct: 181 EDAGLFFCTAHNKLGKAHAQVQLIVVNKPSIKTNFLDEETVNMSCEVELTCENSAECPEA 240
Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSAS-----LTIK---KVENTDAGIYKL-RLENNCGH 1368
EW +N + K+ K + K + L K +V + AG ++ R + +
Sbjct: 241 LFEWKINDRPAKEYPSLKSKVHEKKSGHKGRHLKQKVDLEVPKSLAGSRQIGRFACSSLY 300
Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSS-----INICWDEPENTGNST-----IIYYVVE 1418
VT PSP + ++D + W P ++ + Y+VE
Sbjct: 301 GGSSEFVTKPQLPSPIAL-TVEQMDEDGKKKKMFRLRWRLPPQHRDTRDHSPKVEGYLVE 359
Query: 1419 YQEIDTTEWIS-----VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
+ +W + V N+ K +++NL N+ Y+FR +V I + S +++ K
Sbjct: 360 LRTRKNRKWRAAERQLVGNMEKDSITVENLLPNTEYQFRVRSVESAAIGEPSIPSDWVK 418
Score = 38.7 bits (86), Expect = 0.045
Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 6/135 (4%)
Query: 832 PPLFINRFQEITVKEKGTIKLVARVTR-NPVPSITWYRNNEIISPSETITQNFDGENIEL 890
PP + + V + + ++ + S+ W+++ + I P + I+
Sbjct: 18 PPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDH 77
Query: 891 VITNVD--SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH-LQKSYETEEGKTVI 947
+ ++ E DSG Y+CVASN G SS A +T+ F + + + G TV
Sbjct: 78 NVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFPPNAMSRKVFAAFGSTVS 137
Query: 948 LEC--QTSHTVSTKW 960
+ C + S KW
Sbjct: 138 IPCIFEASPRFHGKW 152
Score = 38.3 bits (85), Expect = 0.059
Identities = 54/248 (21%), Positives = 100/248 (40%), Gaps = 21/248 (8%)
Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG-NPRPTITWCKN 771
+N G A+ + +K++ PP +++ L +V +V + + ++ W K+
Sbjct: 1 MNAFGSAAGEVHVKLRA----PPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKD 56
Query: 772 NKPVKALPTKSDGDT-----HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
KP+ L ++ H++ LK D GVY A N G + +SA++TV++
Sbjct: 57 AKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSA 116
Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
PP ++R ++ T+ + +P W P + ++ +G
Sbjct: 117 P--VFPPNAMSR--KVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKGRIRDEEGV 172
Query: 887 -NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
+IE V+ D+G + C A N GK +H I V K + +
Sbjct: 173 ISIEKVLHE-----DAGLFFCTAHNKLGK-AHAQVQLIVVNKPSIKTNFLDEETVNMSCE 226
Query: 946 VILECQTS 953
V L C+ S
Sbjct: 227 VELTCENS 234
Score = 37.9 bits (84), Expect = 0.078
Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
GSTV C E PR W P + D++ V + I +V EDAG F C
Sbjct: 133 GSTVSIPCIFEASPRFHGKWADAGGSKLPQKG--RIRDEEGVIS--IEKVLHEDAGLFFC 188
Query: 584 VAKNAAGFASSTTELIV 600
A N G A + +LIV
Sbjct: 189 TAHNKLGKAHAQVQLIV 205
Score = 37.5 bits (83), Expect = 0.10
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPR-PQITWFRQTA----IIKPSQDFQMYYDDDN 564
P ++ L + P S V FEC + + WF+ ++ P++ + D N
Sbjct: 19 PSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHN 78
Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
V L + D+G + CVA N G +SS+ L V+
Sbjct: 79 VLHLKFAD--ETDSGVYQCVASNDVGSSSSSALLTVK 113
Score = 33.1 bits (72), Expect = 2.2
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 1701 YAIEKHEPDNNRWIK-----VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754
Y +E N +W V ++++D T ++ L N EY FRV + E ++
Sbjct: 356 YLVELRTRKNRKWRAAERQLVGNMEKDSIT--VENLLPNTEYQFRVRSVESAAIGEPSIP 413
Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
S+ +KTA PS +D++++ + W P E
Sbjct: 414 SD--WVKTAPGAPSETIDNLKWRSLDSQTLLVEWQPIE 449
>Z68005-3|CAA91990.1| 1227|Caenorhabditis elegans Hypothetical
protein F59F3.1 protein.
Length = 1227
Score = 46.0 bits (104), Expect = 3e-04
Identities = 68/308 (22%), Positives = 135/308 (43%), Gaps = 47/308 (15%)
Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKG------EEIVPDENISVAIESDMHMYCSVLK 696
+Y +++ +EC ++IP D+ + +K +EI P++ +SV D +
Sbjct: 472 EYYKPDTNLHIECISISIPPADVVFEYKTKNSEQFQEIEPNKLVSVGGTFDRGL------ 525
Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE--------KEPPQVIEPLKSMIVRQ 748
I NV F EG + R+G ++ + IK GE ++ + E S I+ +
Sbjct: 526 IYNVT-FTEGMDLKCSSIRKGNRAITVNKLIKIGEGFEVRPHHEKSSKATESEPSKIIYE 584
Query: 749 GESVILSAQV-VGNPRPTITW-CKNNKP--VKALPTKSDGDT-----HSITILKPKKVKD 799
G++V L+ + + +++W +N+K + ++PT ++ + H I L+
Sbjct: 585 GDNVKLTCVFPLDSDDWSVSWRFENSKSSDISSIPTTTETEIKQYSKHLILNLRDVTTSF 644
Query: 800 EGVYT--LKAENSEGIAETSA-VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
G YT +K E+SE + ETS V + +P+ N + V ++ +
Sbjct: 645 TGTYTCVVKNEDSEKLLETSIDVKAISKPSITGG------NSNAVVIVDYDQYFEINCNM 698
Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
T P P W+++ + + DG + ++ E D G++ C+A+N AG
Sbjct: 699 TGTPPPVYQWFKDGNPYTHGDV-----DGSILR--VSRARGE-DDGEFHCLATNRAGDKL 750
Query: 917 HGARVTID 924
+ V ++
Sbjct: 751 NSIEVQVN 758
Score = 41.9 bits (94), Expect = 0.005
Identities = 53/266 (19%), Positives = 100/266 (37%), Gaps = 26/266 (9%)
Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE----VDISDASETTEYYKV 1473
++QEI+ + +SV T + I N+ + ++ + + ++ + E ++V
Sbjct: 505 QFQEIEPNKLVSVGG-TFDRGLIYNVTFTEGMDLKCSSIRKGNRAITVNKLIKIGEGFEV 563
Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFG-GVPQPKVTWYRDGKK------LKTAK 1526
+ S E I E ++++LTC+F V+W + K + T
Sbjct: 564 RPHHEKSSKATESEPSKIIYE-GDNVKLTCVFPLDSDDWSVSWRFENSKSSDISSIPTTT 622
Query: 1527 AT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVGIQQKPVITISNEDI 1580
T Y Y C+ N+ E +ETS V KP IT N +
Sbjct: 623 ETEIKQYSKHLILNLRDVTTSFTGTYTCVVKNEDSEKLLETSIDVKAISKPSITGGNSNA 682
Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
+ + + G PPP W+K+GN + S++R+ +
Sbjct: 683 VVIVDYDQYFEINCNMTGTPPPVYQWFKDGNPYTHG-------DVDGSILRVSRARGEDD 735
Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKP 1666
++ A+N AG + ++V + P
Sbjct: 736 GEFHCLATNRAGDKLNSIEVQVNNAP 761
>Z49911-9|CAA90133.1| 682|Caenorhabditis elegans Hypothetical
protein M28.7 protein.
Length = 682
Score = 45.2 bits (102), Expect = 5e-04
Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
Query: 363 QEKQTLEELPKEDVPEQYTIT-PRKSSA----QKIDEIVDEVTIKKRLNPFEIFYTPVEV 417
Q Q + P+ + TIT P +S Q++DE++ + R + E+ PV V
Sbjct: 157 QPPQQQHQQPQPKPRQPITITKPLESKTLNERQELDEVISRLQNPSRGDSGEVM-EPVVV 215
Query: 418 RCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDE 477
R G+ A+ S+ AE + + L++G++ I T + WW + +G VP YL
Sbjct: 216 R-GNVFVAIDSWDAEAEGDLELIKGKKYRITQTRSDGWWTALDEYGQ-RGLVPKTYLQHV 273
Query: 478 NNYTQYLQKKLNEKI 492
+ + K++ ++
Sbjct: 274 KEKPKNVPSKVSSRL 288
>Z81045-4|CAB54202.2| 402|Caenorhabditis elegans Hypothetical
protein C36F7.4b protein.
Length = 402
Score = 44.8 bits (101), Expect = 7e-04
Identities = 46/172 (26%), Positives = 65/172 (37%), Gaps = 17/172 (9%)
Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620
D N L I+ V D G ++C N ST EL V+A + HG + +
Sbjct: 149 DLHNEWVLTIKNVQESDRGNYSCQI-NTEPITLSTGELDVKASVF-HGPVLHLTKVSRKH 206
Query: 621 XXXXXADILEGIPP----------TFSKKPKAQ----YVDEGSDILLECRLVAIPEPDIA 666
GIPP TF +AQ GS + C A P P++
Sbjct: 207 MSEYLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQASVGSMARMVCTTEAWPRPEMG 266
Query: 667 WLFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
W GE + N+++ S + +L+I NV+ G Y VA N G
Sbjct: 267 WEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNG 318
Score = 38.3 bits (85), Expect = 0.059
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD----NVATLVIREVFPEDAG 579
GS + C E +PRP++ W + + S + M + +V L IR V G
Sbjct: 248 GSMARMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFG 307
Query: 580 TFTCVAKNAAGFASSTTEL 598
+ CVAKN G S L
Sbjct: 308 VYRCVAKNDNGIHHSQVTL 326
Score = 35.1 bits (77), Expect = 0.55
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 12/135 (8%)
Query: 694 VLKITNVKKFQEGTYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
VL +T V + Y VA N + S + L + PP V +++ G
Sbjct: 196 VLHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTF----PPLVQAQSETVQASVGSMA 251
Query: 753 ILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDE--GVYTL 805
+ PRP + W K+ +PV A+ G HS+ IL+ + V+ GVY
Sbjct: 252 RMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRC 311
Query: 806 KAENSEGIAETSAVI 820
A+N GI + +
Sbjct: 312 VAKNDNGIHHSQVTL 326
Score = 33.5 bits (73), Expect = 1.7
Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 1253 LIIRKCTEDDQCEYTCVLL-----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
L + K + EY CV D T KL +V FPP + + GS +
Sbjct: 197 LHLTKVSRKHMSEYLCVASNGIPPDESWTVKL---LVTFPPLVQAQSETVQASVGSMARM 253
Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCK-----HTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
+ +A+P+P W + + + + HT L I+ V+++ G+Y+
Sbjct: 254 VCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVA 313
Query: 1363 ENNCG--HADVEMN 1374
+N+ G H+ V +N
Sbjct: 314 KNDNGIHHSQVTLN 327
Score = 33.5 bits (73), Expect = 1.7
Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 8/119 (6%)
Query: 1548 YKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
Y C+A N E+ V + + P++ +E ++ VG + E P PE+ W
Sbjct: 210 YLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQAS--VGSMARMVCTTEAWPRPEMGW 267
Query: 1607 YKNGNKLENDKEYNITTK-----EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
K+G + +T ++ I+ ++ SH Y A N G +VTL
Sbjct: 268 EKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNGIHHSQVTL 326
>Z81045-3|CAB02817.3| 280|Caenorhabditis elegans Hypothetical
protein C36F7.4a protein.
Length = 280
Score = 44.8 bits (101), Expect = 7e-04
Identities = 46/172 (26%), Positives = 65/172 (37%), Gaps = 17/172 (9%)
Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620
D N L I+ V D G ++C N ST EL V+A + HG + +
Sbjct: 59 DLHNEWVLTIKNVQESDRGNYSCQI-NTEPITLSTGELDVKASVF-HGPVLHLTKVSRKH 116
Query: 621 XXXXXADILEGIPP----------TFSKKPKAQ----YVDEGSDILLECRLVAIPEPDIA 666
GIPP TF +AQ GS + C A P P++
Sbjct: 117 MSEYLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQASVGSMARMVCTTEAWPRPEMG 176
Query: 667 WLFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
W GE + N+++ S + +L+I NV+ G Y VA N G
Sbjct: 177 WEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNG 228
Score = 38.3 bits (85), Expect = 0.059
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD----NVATLVIREVFPEDAG 579
GS + C E +PRP++ W + + S + M + +V L IR V G
Sbjct: 158 GSMARMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFG 217
Query: 580 TFTCVAKNAAGFASSTTEL 598
+ CVAKN G S L
Sbjct: 218 VYRCVAKNDNGIHHSQVTL 236
Score = 35.1 bits (77), Expect = 0.55
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 12/135 (8%)
Query: 694 VLKITNVKKFQEGTYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
VL +T V + Y VA N + S + L + PP V +++ G
Sbjct: 106 VLHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTF----PPLVQAQSETVQASVGSMA 161
Query: 753 ILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDE--GVYTL 805
+ PRP + W K+ +PV A+ G HS+ IL+ + V+ GVY
Sbjct: 162 RMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRC 221
Query: 806 KAENSEGIAETSAVI 820
A+N GI + +
Sbjct: 222 VAKNDNGIHHSQVTL 236
Score = 33.5 bits (73), Expect = 1.7
Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 1253 LIIRKCTEDDQCEYTCVLL-----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
L + K + EY CV D T KL +V FPP + + GS +
Sbjct: 107 LHLTKVSRKHMSEYLCVASNGIPPDESWTVKL---LVTFPPLVQAQSETVQASVGSMARM 163
Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCK-----HTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
+ +A+P+P W + + + + HT L I+ V+++ G+Y+
Sbjct: 164 VCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVA 223
Query: 1363 ENNCG--HADVEMN 1374
+N+ G H+ V +N
Sbjct: 224 KNDNGIHHSQVTLN 237
Score = 33.5 bits (73), Expect = 1.7
Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 8/119 (6%)
Query: 1548 YKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
Y C+A N E+ V + + P++ +E ++ VG + E P PE+ W
Sbjct: 120 YLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQAS--VGSMARMVCTTEAWPRPEMGW 177
Query: 1607 YKNGNKLENDKEYNITTK-----EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
K+G + +T ++ I+ ++ SH Y A N G +VTL
Sbjct: 178 EKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNGIHHSQVTL 236
>Z83235-2|CAB05773.2| 265|Caenorhabditis elegans Hypothetical
protein K10C3.3 protein.
Length = 265
Score = 44.4 bits (100), Expect = 0.001
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G +V C V GYP+P + W + +A + SQ M +T+++ DAGT++C
Sbjct: 148 GESVTLTCPVTGYPKPVVKWTKDSAPLALSQSVSM-----EGSTVIVTNANYTDAGTYSC 202
Query: 584 VAKNAAGFASSTTELIV 600
A N T+++++
Sbjct: 203 EAVNEYTVNGKTSKMLL 219
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/232 (22%), Positives = 94/232 (40%), Gaps = 25/232 (10%)
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
TV A+ G S +++ ++ E P +P+ V++ I
Sbjct: 14 TVTALGGRGSKSALVLVAARSSENHPLHATDPITIWCAPDNPQVVIKTAHF------IRS 67
Query: 769 CKNNKPVKAL-PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-------IAETSAVI 820
N K AL PTK + + T P VKD G Y + + G I V
Sbjct: 68 SDNEKLEAALNPTKKNA---TYTFGSPS-VKDAGEYKCELDTPHGKISHKVFIYSRPVVH 123
Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
+ E TE F TV++ ++ L VT P P + W +++ ++ S++++
Sbjct: 124 SHEHFTEHEGHE--FHLESTGTTVEKGESVTLTCPVTGYPKPVVKWTKDSAPLALSQSVS 181
Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
E +++TN + D+G Y C A N + +++ + V+K+ V+
Sbjct: 182 M----EGSTVIVTNA-NYTDAGTYSCEAVNEYTVNGKTSKMLLVVDKMVDVR 228
Score = 37.1 bits (82), Expect = 0.14
Identities = 34/150 (22%), Positives = 57/150 (38%), Gaps = 15/150 (10%)
Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481
I T +I + K + ++ K N++Y F + +V + T + K+ + I S
Sbjct: 59 IKTAHFIRSSDNEKLEAALNPTKKNATYTFGSPSVKDAGEYKCELDTPHGKISHKVFIYS 118
Query: 1482 -PTV------------EKPLKNI--TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P V E L++ T E E + LTC G P+P V W +D L ++
Sbjct: 119 RPVVHSHEHFTEHEGHEFHLESTGTTVEKGESVTLTCPVTGYPKPVVKWTKDSAPLALSQ 178
Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+ Y C A N++
Sbjct: 179 SVSMEGSTVIVTNANYTDAGTYSCEAVNEY 208
Score = 33.1 bits (72), Expect = 2.2
Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V++G + L C + P+P + W ++ +A+ + M S + +TN
Sbjct: 145 VEKGESVTLTCPVTGYPKPVVKW--------TKDSAPLALSQSVSMEGSTVIVTNANYTD 196
Query: 705 EGTYTVVAVN 714
GTY+ AVN
Sbjct: 197 AGTYSCEAVN 206
>AL023843-1|CAA19522.2| 260|Caenorhabditis elegans Hypothetical
protein Y48A6A.1 protein.
Length = 260
Score = 44.4 bits (100), Expect = 0.001
Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 26/208 (12%)
Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK 798
+PL+++ +G+S++L +P+PTI W K V + P S T L V+
Sbjct: 49 KPLENIKANRGDSLVLRCAFYASPQPTIVWYHRGKRVDSHPAAHFETLLSATNLGQSVVE 108
Query: 799 --------DE---GVYTLKAEN--SEGIAETSAVITVEEPTE---------ENAEPPLFI 836
DE G Y +A + ++ + +S V + P + E P +
Sbjct: 109 SALRIDCLDERTAGEYFCEATSPCTQPVVTSSTVTINKAPKSITGTCKSIRQPLESPPIV 168
Query: 837 NRFQEITVKEKGTI-KLVARVTRNPVPSITWYR--NNEIISPSETITQNFDGENIELVIT 893
+ F ++ G + +L RV P P W++ +E +S + N +L+I
Sbjct: 169 SDFTLSRIELPGGVAQLACRVRGVPTPKTKWFKIEEDESLSTIDGQPNYMHLSNGDLLIV 228
Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARV 921
D E S ++CVASN G A V
Sbjct: 229 G-DEETISESFRCVASNPLGSVHQDASV 255
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/47 (34%), Positives = 27/47 (57%)
Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
+++KPL+NI + + L C F PQP + WY GK++ + A +
Sbjct: 46 SIDKPLENIKANRGDSLVLRCAFYASPQPTIVWYHRGKRVDSHPAAH 92
Score = 32.3 bits (70), Expect = 3.9
Identities = 37/173 (21%), Positives = 62/173 (35%), Gaps = 13/173 (7%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAII--KPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
G ++ C P+P I W+ + + P+ F+ N+ V+ E A
Sbjct: 59 GDSLVLRCAFYASPQPTIVWYHRGKRVDSHPAAHFETLLSATNLGQSVV-----ESALRI 113
Query: 582 TCVAKNAAG-FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP 640
C+ + AG + T + ++ + LE PP S
Sbjct: 114 DCLDERTAGEYFCEATSPCTQPVVTSSTVTINKAPKSITGTCKSIRQPLES-PPIVSDFT 172
Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
++ G L CR+ +P P W FK EE DE++S +M+ S
Sbjct: 173 LSRIELPGGVAQLACRVRGVPTPKTKW-FKIEE---DESLSTIDGQPNYMHLS 221
Score = 31.1 bits (67), Expect = 9.0
Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 7/80 (8%)
Query: 524 GSTVQFECQVEGYPRPQITWFR----QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
G Q C+V G P P+ WF+ ++ Q M+ + ++ + E E
Sbjct: 180 GGVAQLACRVRGVPTPKTKWFKIEEDESLSTIDGQPNYMHLSNGDLLIVGDEETISE--- 236
Query: 580 TFTCVAKNAAGFASSTTELI 599
+F CVA N G +I
Sbjct: 237 SFRCVASNPLGSVHQDASVI 256
>AF456248-1|AAL59606.1| 265|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-1 protein.
Length = 265
Score = 44.4 bits (100), Expect = 0.001
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G +V C V GYP+P + W + +A + SQ M +T+++ DAGT++C
Sbjct: 148 GESVTLTCPVTGYPKPVVKWTKDSAPLALSQSVSM-----EGSTVIVTNANYTDAGTYSC 202
Query: 584 VAKNAAGFASSTTELIV 600
A N T+++++
Sbjct: 203 EAVNEYTVNGKTSKMLL 219
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/232 (22%), Positives = 94/232 (40%), Gaps = 25/232 (10%)
Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
TV A+ G S +++ ++ E P +P+ V++ I
Sbjct: 14 TVTALGGRGSKSALVLVAARSSENHPLHATDPITIWCAPDNPQVVIKTAHF------IRS 67
Query: 769 CKNNKPVKAL-PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-------IAETSAVI 820
N K AL PTK + + T P VKD G Y + + G I V
Sbjct: 68 SDNEKLEAALNPTKKNA---TYTFGSPS-VKDAGEYKCELDTPHGKISHKVFIYSRPVVH 123
Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
+ E TE F TV++ ++ L VT P P + W +++ ++ S++++
Sbjct: 124 SHEHFTEHEGHE--FHLESTGTTVEKGESVTLTCPVTGYPKPVVKWTKDSAPLALSQSVS 181
Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
E +++TN + D+G Y C A N + +++ + V+K+ V+
Sbjct: 182 M----EGSTVIVTNA-NYTDAGTYSCEAVNEYTVNGKTSKMLLVVDKMVDVR 228
Score = 37.1 bits (82), Expect = 0.14
Identities = 34/150 (22%), Positives = 57/150 (38%), Gaps = 15/150 (10%)
Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481
I T +I + K + ++ K N++Y F + +V + T + K+ + I S
Sbjct: 59 IKTAHFIRSSDNEKLEAALNPTKKNATYTFGSPSVKDAGEYKCELDTPHGKISHKVFIYS 118
Query: 1482 -PTV------------EKPLKNI--TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
P V E L++ T E E + LTC G P+P V W +D L ++
Sbjct: 119 RPVVHSHEHFTEHEGHEFHLESTGTTVEKGESVTLTCPVTGYPKPVVKWTKDSAPLALSQ 178
Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
+ Y C A N++
Sbjct: 179 SVSMEGSTVIVTNANYTDAGTYSCEAVNEY 208
Score = 33.1 bits (72), Expect = 2.2
Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
V++G + L C + P+P + W ++ +A+ + M S + +TN
Sbjct: 145 VEKGESVTLTCPVTGYPKPVVKW--------TKDSAPLALSQSVSMEGSTVIVTNANYTD 196
Query: 705 EGTYTVVAVN 714
GTY+ AVN
Sbjct: 197 AGTYSCEAVN 206
>Z93395-1|CAB07704.1| 1160|Caenorhabditis elegans Hypothetical
protein ZC101.2b protein.
Length = 1160
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDG 784
+ G +P V P ++ V +G + L+ + V P P I W N PV P S+G
Sbjct: 265 EVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEG 324
Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVI-TVEEPTEENAEPP 833
++TI + V D+G YT +A N +G +A ++ V++P + +PP
Sbjct: 325 GYGTLTIHDAQPV-DQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQPP 375
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
P G+T C+ P P I W + +P + Q + TL I + P D G
Sbjct: 284 PRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQT--SEGGYGTLTIHDAQPVDQGA 341
Query: 581 FTCVAKNAAGFASSTTELIV 600
+TC A N G +T + IV
Sbjct: 342 YTCEAINVKGRVLATPDCIV 361
Score = 36.7 bits (81), Expect = 0.18
Identities = 29/109 (26%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
+ PT P+ V G+ L C+ VA+PEP I W + E
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGY-- 326
Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVLKIKTGEKEPPQ 736
L I + + +G YT A+N +G + P IV + +PPQ
Sbjct: 327 --GTLTIHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPRPQPPQ 373
>AF456252-1|AAL59610.1| 259|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-5 protein.
Length = 259
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/47 (34%), Positives = 27/47 (57%)
Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
+++KPL+NI + + L C F PQP + WY GK++ + A +
Sbjct: 46 SIDKPLENIKANRGDSLVLRCAFYASPQPTIVWYHRGKRVDSHPAAH 92
Score = 36.7 bits (81), Expect = 0.18
Identities = 47/207 (22%), Positives = 80/207 (38%), Gaps = 25/207 (12%)
Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK 798
+PL+++ +G+S++L +P+PTI W K V + P S T L V+
Sbjct: 49 KPLENIKANRGDSLVLRCAFYASPQPTIVWYHRGKRVDSHPAAHFETLLSATNLGQSVVE 108
Query: 799 --------DEGV----------YTLKAENSEGIAETSAVITVEEPTEENAEP---PLFIN 837
DE + L + A ++ + +P P ++
Sbjct: 109 SALRIDCLDERTGASISAKPRHHALNQRHFVNSTINKAPKSITGTCKSIRQPLESPPIVS 168
Query: 838 RFQEITVKEKGTI-KLVARVTRNPVPSITWYR--NNEIISPSETITQNFDGENIELVITN 894
F ++ G + +L RV P P W++ +E +S + N +L+I
Sbjct: 169 DFTLSRIELPGGVAQLACRVRGVPTPKTKWFKIEEDESLSTIDGQPNYMHLSNGDLLIVG 228
Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARV 921
D E S ++CVASN G A V
Sbjct: 229 -DEETISESFRCVASNPLGSVHQDASV 254
Score = 31.1 bits (67), Expect = 9.0
Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 7/80 (8%)
Query: 524 GSTVQFECQVEGYPRPQITWFR----QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
G Q C+V G P P+ WF+ ++ Q M+ + ++ + E E
Sbjct: 179 GGVAQLACRVRGVPTPKTKWFKIEEDESLSTIDGQPNYMHLSNGDLLIVGDEETISE--- 235
Query: 580 TFTCVAKNAAGFASSTTELI 599
+F CVA N G +I
Sbjct: 236 SFRCVASNPLGSVHQDASVI 255
>Z81543-5|CAB04427.2| 507|Caenorhabditis elegans Hypothetical
protein F49B2.5 protein.
Length = 507
Score = 43.2 bits (97), Expect = 0.002
Identities = 16/55 (29%), Positives = 32/55 (58%)
Query: 425 AVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENN 479
A++ Y A TD+ ++ + + L IL+ + DWW+ + T G++P+ Y+ E +
Sbjct: 64 ALFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATGRTGYIPSNYVAREKS 118
>Z68005-1|CAA91991.1| 1199|Caenorhabditis elegans Hypothetical
protein F59F3.5 protein.
Length = 1199
Score = 43.2 bits (97), Expect = 0.002
Identities = 38/179 (21%), Positives = 74/179 (41%), Gaps = 10/179 (5%)
Query: 637 SKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
+K + + EG ++ L C + E D+ W F+ +++ +L
Sbjct: 584 TKTEPSDIIFEGDNVRLTCVVPYGAVEFDVFWKFENPKMLKYTTFPAMHPVKDRYKRVIL 643
Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR--QGESVI 753
+ N+ GTY + N+E E + ++ + PP ++ I+ G+
Sbjct: 644 NVRNITIDFTGTYYCIVKNKEFEHRFETSISVE--KVSPPFLLNNNSRSIISASNGQMFD 701
Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
++ +V G P P TW K+ P TK +++ + K +K +D G++ A N G
Sbjct: 702 INCKVNGVPTPDYTWFKDGYPY----TKGKVIGNALHVSKAEK-RDNGIFWCSATNRAG 755
Score = 39.1 bits (87), Expect = 0.034
Identities = 44/222 (19%), Positives = 82/222 (36%), Gaps = 26/222 (11%)
Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE------DIELTCI--FGGVP- 1509
+++ +T++ V +EK + TEP++ ++ LTC+ +G V
Sbjct: 552 INVKKKKTSTKFITVTSNANKTFHEIEKSVNATKTEPSDIIFEGDNVRLTCVVPYGAVEF 611
Query: 1510 -------QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VE 1560
PK+ Y + K Y+ R Y CI N E E
Sbjct: 612 DVFWKFENPKMLKYTTFPAMHPVKDRYK-RVILNVRNITIDFTGTYYCIVKNKEFEHRFE 670
Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
TS V P + +N G + + + G+P P+ W+K+G K
Sbjct: 671 TSISVEKVSPPFLLNNNSRSIISASNGQMFDINCKVNGVPTPDYTWFKDGYPYTKGKVIG 730
Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
+ + + + ++ + + A+N AGT+ + +KV
Sbjct: 731 -------NALHVSKAEKRDNGIFWCSATNRAGTTIDYIEVKV 765
>U29487-1|AAA68768.1| 253|Caenorhabditis elegans 2 (zwei) ig-domain
protein protein4 protein.
Length = 253
Score = 42.7 bits (96), Expect = 0.003
Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 24/198 (12%)
Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT-----------KSDG 784
+++ PL+S ++ GE+ L ++ P TI W N K ++ K+
Sbjct: 47 KIVAPLESALIPGGETYQLRCDIMSTPAATIHWKFNGKLIQGSNELNVEEKLLNFGKAIV 106
Query: 785 DTH---SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE---ENAEPPLFINR 838
DT SI ++ ++ G Y+ N ET A + +E N + I
Sbjct: 107 DTGIVASILTIQCPSAENSGTYSCVGYNGHQTIETVAEVEIEGEASGCRSNHKSAPEIVF 166
Query: 839 FQEITVKEKGTIK-LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
+ + + G + LV R N W N+E++ ++ T +G+ LVI N+
Sbjct: 167 WTDSRFEMTGNVATLVCRA--NQQVDWVWMSNDELVKNNDKFTVLSNGD---LVIKNIVW 221
Query: 898 EIDSGDYKCVASNSAGKS 915
+ D G Y C+A N G++
Sbjct: 222 D-DMGTYTCIARNQFGEA 238
Score = 35.9 bits (79), Expect = 0.32
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
W ++K + F + + D LVI+ + +D GT+TC+A+N G A T L A
Sbjct: 193 WMSNDELVKNNDKFTVLSNGD----LVIKNIVWDDMGTYTCIARNQFGEARQETFLYPTA 248
Query: 603 PLS 605
S
Sbjct: 249 KKS 251
>AL117200-10|CAB55046.1| 151|Caenorhabditis elegans Hypothetical
protein Y50E8A.3 protein.
Length = 151
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 3/116 (2%)
Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543
L K++N ++P K + + AP F++ G F+C + G PRP++ W
Sbjct: 35 LTKQVNHLAYEIPK-NKYANNPWNYAPEFLKVFGDLRVHIGGKAVFDCVLLGSPRPRVCW 93
Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
++ S + D +V L I V GTFT + +N G A++ EL+
Sbjct: 94 LFNEDKLRFSD--VIIEDTADVCRLTIPYVQMHHFGTFTVLCENEVGRATAQAELL 147
Score = 35.5 bits (78), Expect = 0.42
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 5/87 (5%)
Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
P F K V G + +C L+ P P + WLF +++ S I D C
Sbjct: 60 PEFLKVFGDLRVHIGGKAVFDCVLLGSPRPRVCWLFNEDKL----RFSDVIIEDTADVCR 115
Query: 694 VLKITNVKKFQEGTYTVVAVNREGEAS 720
L I V+ GT+TV+ N G A+
Sbjct: 116 -LTIPYVQMHHFGTFTVLCENEVGRAT 141
>AF456251-1|AAL59609.1| 253|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-4 protein.
Length = 253
Score = 42.7 bits (96), Expect = 0.003
Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 24/198 (12%)
Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT-----------KSDG 784
+++ PL+S ++ GE+ L ++ P TI W N K ++ K+
Sbjct: 47 KIVAPLESALIPGGETYQLRCDIMSTPAATIHWKFNGKLIQGSNELNVEEKLLNFGKAIV 106
Query: 785 DTH---SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE---ENAEPPLFINR 838
DT SI ++ ++ G Y+ N ET A + +E N + I
Sbjct: 107 DTGIVASILTIQCPSAENSGTYSCVGYNGHQTIETVAEVEIEGEASGCRSNHKSAPEIVF 166
Query: 839 FQEITVKEKGTIK-LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
+ + + G + LV R N W N+E++ ++ T +G+ LVI N+
Sbjct: 167 WTDSRFEMTGNVATLVCRA--NQQVDWVWMSNDELVKNNDKFTVLSNGD---LVIKNIVW 221
Query: 898 EIDSGDYKCVASNSAGKS 915
+ D G Y C+A N G++
Sbjct: 222 D-DMGTYTCIARNQFGEA 238
Score = 35.9 bits (79), Expect = 0.32
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
W ++K + F + + D LVI+ + +D GT+TC+A+N G A T L A
Sbjct: 193 WMSNDELVKNNDKFTVLSNGD----LVIKNIVWDDMGTYTCIARNQFGEARQETFLYPTA 248
Query: 603 PLS 605
S
Sbjct: 249 KKS 251
>Z49938-5|CAD31752.1| 1467|Caenorhabditis elegans Hypothetical protein
C09D8.1b protein.
Length = 1467
Score = 42.3 bits (95), Expect = 0.004
Identities = 51/201 (25%), Positives = 84/201 (41%), Gaps = 21/201 (10%)
Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK------SWTKIVTVG 1919
PS PRNF +++ SV L W P + G+ + Y+ + V G+ S +IV +
Sbjct: 37 PSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIR 96
Query: 1920 GSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
S + ++++ E FR++A N G +E +S+ T PP AP EI V
Sbjct: 97 DSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIPPEAP-EIVSV 150
Query: 1979 GSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVDVNTLKFNIRD 2030
+ + W P+ P+ YN+ +R +++ VD L I
Sbjct: 151 SLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISG 210
Query: 2031 LSENHTYMIRIYARNEIGLSE 2051
L Y + + A N G S+
Sbjct: 211 LWMGVVYDVLLAAENREGRSQ 231
Score = 36.7 bits (81), Expect = 0.18
Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 31/273 (11%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEG-PV-IMREISRESVTIEWKPPLDD---GGLELT 1699
+ A N G S T + P+G P+ + E+ + + + W+PP ++ G +
Sbjct: 221 LAAENREGRSQ-NATETIATPVGSPDGEPIDVQYEVMKGKIVVSWRPPSEEKRNGNITSY 279
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756
K + + +R+ + T+ ++N Y+F+V A G +S L
Sbjct: 280 KAILSAMDATADRYEQPVPAPSTSSTF---EVNVRRAYLFKVAAATMKGIGPYSPVLTIN 336
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWK 1814
P AL P N + + W + S ++ Y E + + +KWK
Sbjct: 337 PD--PAALVGPPTNVRVEATS---NSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWK 391
Query: 1815 XXXXXXXXX------ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
A + L+ + Y F + A + + D T+ +++TP
Sbjct: 392 QLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLA---VKNNRQGPCSDPPTVLESVTPTYM 448
Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
+N V TS SV L W E NG + Y+
Sbjct: 449 VQNLRVLWKTSNSVQLTW---EYNGPRNVGFYV 478
>Z46811-2|CAD31753.1| 1467|Caenorhabditis elegans Hypothetical protein
C09D8.1b protein.
Length = 1467
Score = 42.3 bits (95), Expect = 0.004
Identities = 51/201 (25%), Positives = 84/201 (41%), Gaps = 21/201 (10%)
Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK------SWTKIVTVG 1919
PS PRNF +++ SV L W P + G+ + Y+ + V G+ S +IV +
Sbjct: 37 PSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIR 96
Query: 1920 GSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
S + ++++ E FR++A N G +E +S+ T PP AP EI V
Sbjct: 97 DSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIPPEAP-EIVSV 150
Query: 1979 GSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVDVNTLKFNIRD 2030
+ + W P+ P+ YN+ +R +++ VD L I
Sbjct: 151 SLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISG 210
Query: 2031 LSENHTYMIRIYARNEIGLSE 2051
L Y + + A N G S+
Sbjct: 211 LWMGVVYDVLLAAENREGRSQ 231
Score = 36.7 bits (81), Expect = 0.18
Identities = 57/273 (20%), Positives = 102/273 (37%), Gaps = 31/273 (11%)
Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEG-PV-IMREISRESVTIEWKPPLDD---GGLELT 1699
+ A N G S T + P+G P+ + E+ + + + W+PP ++ G +
Sbjct: 221 LAAENREGRSQ-NATETIATPVGSPDGEPIDVQYEVMKGKIVVSWRPPSEEKRNGNITSY 279
Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756
K + + +R+ + T+ ++N Y+F+V A G +S L
Sbjct: 280 KAILSAMDATADRYEQPVPAPSTSSTF---EVNVRRAYLFKVAAATMKGIGPYSPVLTIN 336
Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWK 1814
P AL P N + + W + S ++ Y E + + +KWK
Sbjct: 337 PD--PAALVGPPTNVRVEATS---NSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWK 391
Query: 1815 XXXXXXXXX------ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
A + L+ + Y F + A + + D T+ +++TP
Sbjct: 392 QLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLA---VKNNRQGPCSDPPTVLESVTPTYM 448
Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
+N V TS SV L W E NG + Y+
Sbjct: 449 VQNLRVLWKTSNSVQLTW---EYNGPRNVGFYV 478
>AF316540-1|AAK01633.1| 1487|Caenorhabditis elegans PTP-3B protein.
Length = 1487
Score = 42.3 bits (95), Expect = 0.004
Identities = 51/201 (25%), Positives = 84/201 (41%), Gaps = 21/201 (10%)
Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK------SWTKIVTVG 1919
PS PRNF +++ SV L W P + G+ + Y+ + V G+ S +IV +
Sbjct: 37 PSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIR 96
Query: 1920 GSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
S + ++++ E FR++A N G +E +S+ T PP AP EI V
Sbjct: 97 DSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIPPEAP-EIVSV 150
Query: 1979 GSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVDVNTLKFNIRD 2030
+ + W P+ P+ YN+ +R +++ VD L I
Sbjct: 151 SLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISG 210
Query: 2031 LSENHTYMIRIYARNEIGLSE 2051
L Y + + A N G S+
Sbjct: 211 LWMGVVYDVLLAAENREGRSQ 231
Score = 31.5 bits (68), Expect = 6.8
Identities = 83/393 (21%), Positives = 136/393 (34%), Gaps = 28/393 (7%)
Query: 1679 SRESVTIEWKPPLDDGGLELTKYA----IEKHEPDNNRWIKVADV---DRDVETYCIQKL 1731
S SV + W P G L Y + EP + K V D + + L
Sbjct: 49 SATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSL 108
Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY--ITW- 1788
+ N EY FR+ A N G E E + I+ T P D V I W
Sbjct: 109 DPNTEYSFRLNAFNRNGDGEFSERKSII--TQGIPPEAPEIVSVSLDRDEPPVVARIEWK 166
Query: 1789 FPSEKNGGSPIIDYKVEIKQEG-----KKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
P K +PI Y + ++ +G K K I L + Y + A N
Sbjct: 167 MPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTT-ISGLWMGVVYDVLLAAEN 225
Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGSPITNYII 1902
G S T +G +P +P + V E + + W P E IT+Y
Sbjct: 226 REGRSQNATETIATPVG---SPDGEPID-VQYEVMKGKIVVSWRPPSEEKRNGNITSYKA 281
Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
+ + V E + + +F+++A G+ + ++ +
Sbjct: 282 ILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVLTINPDPA 340
Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKVD- 2020
A V P +E + +V + + + D + R D K + V +D
Sbjct: 341 ALVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDK 400
Query: 2021 VNTLKFN-IRDLSENHTYMIRIYA-RNEIGLSE 2051
N +F + DL+ + Y + A +N + L+E
Sbjct: 401 ENPKRFAVVSDLNAHKPYAFCVLAVKNNLTLNE 433
>U40942-9|AAC47074.6| 703|Caenorhabditis elegans Synaptogenesis
abnormal protein 1 protein.
Length = 703
Score = 41.5 bits (93), Expect = 0.006
Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 12/125 (9%)
Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL----PPEIITRLQ-NQKVNKGNK 1123
GH L + N +G Y+C E ++ L PP + + + + +++ +
Sbjct: 400 GHGENLTLENVRTWQQGNYNCTATVEGFRKQILSHYLHIRGPPTVSMKDEVSASLDEATE 459
Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID------GKKQKLKIYDCDLDDAGEYS 1177
EI VRW +G EI F+N ++T+ GK+ LKI D +D G Y+
Sbjct: 460 IICEISGRPKTNNVRWTVNGKEINFNNG-RITVHQYPKPYGKESILKIKDLKEEDFGVYN 518
Query: 1178 CEVGN 1182
C N
Sbjct: 519 CSANN 523
>U80437-19|AAB37630.2| 580|Caenorhabditis elegans Conserved
oligomeric golgi (cog)component protein 5 protein.
Length = 580
Score = 41.1 bits (92), Expect = 0.008
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 154 EKSDLFDSQEDESKPDVSQPPQN--IIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINV 211
EK D+ E E + D++ P+ I+E+ + +P+ I E+E +K SE D V +
Sbjct: 114 EKKDVEPEAEPEPEADIAPEPEKVAIVEKPEPKPEPITETEASPSKASEKDAAVEVSVEK 173
Query: 212 PDDK--ETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVD 252
D + + S +P K +++E E P E+++
Sbjct: 174 VDAETAQESDSPQEAEKEKTEPQVELENGGQEEDEPDRDESIE 216
>S47168-2|AAB23866.2| 919|Caenorhabditis elegans UNC-5 protein.
Length = 919
Score = 41.1 bits (92), Expect = 0.008
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 512 FVEKLRPKHTPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
F++ + +G+T+Q CQ E P+ ++TW++ +++P + D +L++
Sbjct: 113 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASD----GSLIM 168
Query: 571 REVFPEDAGTFTCVAKNAA 589
D+G +TC A N A
Sbjct: 169 SAARLSDSGNYTCEATNVA 187
Score = 37.1 bits (82), Expect = 0.14
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 844 VKEKGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902
V+E T++L + + P +TWY++ ++ P + + DG +I + DSG
Sbjct: 122 VQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS----LIMSAARLSDSG 177
Query: 903 DYKCVASNSA 912
+Y C A+N A
Sbjct: 178 NYTCEATNVA 187
Score = 36.7 bits (81), Expect = 0.18
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 636 FSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
F K P AQ V EG+ + L C+ + P+ ++ W G + PD N+ A SD + S
Sbjct: 113 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRA--SDGSLIMSA 170
Query: 695 LKITNVKKFQEGTYTVVAVN 714
++++ G YT A N
Sbjct: 171 ARLSD-----SGNYTCEATN 185
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
E P E+ WYK+G ++ D N+ S+I + + S S YT EA+N A +
Sbjct: 136 ESDPKAELTWYKDGVVVQPDA--NVIRASDGSLI-MSAARLSDSGNYTCEATNVANSRKT 192
Query: 1657 E-VTLKVY 1663
+ V +++Y
Sbjct: 193 DPVEVQIY 200
Score = 32.3 bits (70), Expect = 3.9
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
Query: 1116 QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
Q+V +G + + D A + W+KDG +Q ++ DG L + L D+
Sbjct: 120 QRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS---LIMSAARLSDS 176
Query: 1174 GEYSCEVGN 1182
G Y+CE N
Sbjct: 177 GNYTCEATN 185
>S47168-1|AAB23867.2| 947|Caenorhabditis elegans UNC-5 protein.
Length = 947
Score = 41.1 bits (92), Expect = 0.008
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 512 FVEKLRPKHTPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
F++ + +G+T+Q CQ E P+ ++TW++ +++P + D +L++
Sbjct: 141 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASD----GSLIM 196
Query: 571 REVFPEDAGTFTCVAKNAA 589
D+G +TC A N A
Sbjct: 197 SAARLSDSGNYTCEATNVA 215
Score = 37.1 bits (82), Expect = 0.14
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 844 VKEKGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902
V+E T++L + + P +TWY++ ++ P + + DG +I + DSG
Sbjct: 150 VQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS----LIMSAARLSDSG 205
Query: 903 DYKCVASNSA 912
+Y C A+N A
Sbjct: 206 NYTCEATNVA 215
Score = 36.7 bits (81), Expect = 0.18
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 636 FSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
F K P AQ V EG+ + L C+ + P+ ++ W G + PD N+ A SD + S
Sbjct: 141 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRA--SDGSLIMSA 198
Query: 695 LKITNVKKFQEGTYTVVAVN 714
++++ G YT A N
Sbjct: 199 ARLSD-----SGNYTCEATN 213
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
E P E+ WYK+G ++ D N+ S+I + + S S YT EA+N A +
Sbjct: 164 ESDPKAELTWYKDGVVVQPDA--NVIRASDGSLI-MSAARLSDSGNYTCEATNVANSRKT 220
Query: 1657 E-VTLKVY 1663
+ V +++Y
Sbjct: 221 DPVEVQIY 228
Score = 32.3 bits (70), Expect = 3.9
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
Query: 1116 QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
Q+V +G + + D A + W+KDG +Q ++ DG L + L D+
Sbjct: 148 QRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS---LIMSAARLSDS 204
Query: 1174 GEYSCEVGN 1182
G Y+CE N
Sbjct: 205 GNYTCEATN 213
>AF226866-1|AAF33845.1| 279|Caenorhabditis elegans cell-corpse
engulfment proteinCED-2 protein.
Length = 279
Score = 41.1 bits (92), Expect = 0.008
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL 474
+ V + + E + + +GERL IL +NQDWW + L G VPA Y+
Sbjct: 119 EVVVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNAL-GTTGLVPANYV 171
>AF036698-5|AAB88356.2| 567|Caenorhabditis elegans Uncoordinated
protein 5, isoform b protein.
Length = 567
Score = 41.1 bits (92), Expect = 0.008
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 512 FVEKLRPKHTPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
F++ + +G+T+Q CQ E P+ ++TW++ +++P + D +L++
Sbjct: 113 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASD----GSLIM 168
Query: 571 REVFPEDAGTFTCVAKNAA 589
D+G +TC A N A
Sbjct: 169 SAARLSDSGNYTCEATNVA 187
Score = 37.1 bits (82), Expect = 0.14
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 844 VKEKGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902
V+E T++L + + P +TWY++ ++ P + + DG +I + DSG
Sbjct: 122 VQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS----LIMSAARLSDSG 177
Query: 903 DYKCVASNSA 912
+Y C A+N A
Sbjct: 178 NYTCEATNVA 187
Score = 36.7 bits (81), Expect = 0.18
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 636 FSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
F K P AQ V EG+ + L C+ + P+ ++ W G + PD N+ A SD + S
Sbjct: 113 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRA--SDGSLIMSA 170
Query: 695 LKITNVKKFQEGTYTVVAVN 714
++++ G YT A N
Sbjct: 171 ARLSD-----SGNYTCEATN 185
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
E P E+ WYK+G ++ D N+ S+I + + S S YT EA+N A +
Sbjct: 136 ESDPKAELTWYKDGVVVQPDA--NVIRASDGSLI-MSAARLSDSGNYTCEATNVANSRKT 192
Query: 1657 E-VTLKVY 1663
+ V +++Y
Sbjct: 193 DPVEVQIY 200
Score = 32.3 bits (70), Expect = 3.9
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
Query: 1116 QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
Q+V +G + + D A + W+KDG +Q ++ DG L + L D+
Sbjct: 120 QRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS---LIMSAARLSDS 176
Query: 1174 GEYSCEVGN 1182
G Y+CE N
Sbjct: 177 GNYTCEATN 185
>AF036698-4|AAB88355.1| 919|Caenorhabditis elegans Uncoordinated
protein 5, isoform a protein.
Length = 919
Score = 41.1 bits (92), Expect = 0.008
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 512 FVEKLRPKHTPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
F++ + +G+T+Q CQ E P+ ++TW++ +++P + D +L++
Sbjct: 113 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASD----GSLIM 168
Query: 571 REVFPEDAGTFTCVAKNAA 589
D+G +TC A N A
Sbjct: 169 SAARLSDSGNYTCEATNVA 187
Score = 37.1 bits (82), Expect = 0.14
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 844 VKEKGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902
V+E T++L + + P +TWY++ ++ P + + DG +I + DSG
Sbjct: 122 VQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS----LIMSAARLSDSG 177
Query: 903 DYKCVASNSA 912
+Y C A+N A
Sbjct: 178 NYTCEATNVA 187
Score = 36.7 bits (81), Expect = 0.18
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 636 FSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
F K P AQ V EG+ + L C+ + P+ ++ W G + PD N+ A SD + S
Sbjct: 113 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRA--SDGSLIMSA 170
Query: 695 LKITNVKKFQEGTYTVVAVN 714
++++ G YT A N
Sbjct: 171 ARLSD-----SGNYTCEATN 185
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
E P E+ WYK+G ++ D N+ S+I + + S S YT EA+N A +
Sbjct: 136 ESDPKAELTWYKDGVVVQPDA--NVIRASDGSLI-MSAARLSDSGNYTCEATNVANSRKT 192
Query: 1657 E-VTLKVY 1663
+ V +++Y
Sbjct: 193 DPVEVQIY 200
Score = 32.3 bits (70), Expect = 3.9
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
Query: 1116 QKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
Q+V +G + + D A + W+KDG +Q ++ DG L + L D+
Sbjct: 120 QRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGS---LIMSAARLSDS 176
Query: 1174 GEYSCEVGN 1182
G Y+CE N
Sbjct: 177 GNYTCEATN 185
>AC024776-8|AAK68463.1| 279|Caenorhabditis elegans Cell death
abnormality protein 2 protein.
Length = 279
Score = 41.1 bits (92), Expect = 0.008
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL 474
+ V + + E + + +GERL IL +NQDWW + L G VPA Y+
Sbjct: 119 EVVVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNAL-GTTGLVPANYV 171
>U64858-2|AAN84866.1| 1310|Caenorhabditis elegans Roller: helically
twisted, animalsroll when moving protein 3, isoform c
protein.
Length = 1310
Score = 40.7 bits (91), Expect = 0.011
Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 15/98 (15%)
Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT--LTPPSQPRN---------FVV 1874
I L T+Y +R A GT YT D K+ K L P Q R FV
Sbjct: 542 ITNLLSATSYDYRFVA-TYTGT---YTIDGKVLAFKEDYLQLPQQARTKAGVPTAPQFVE 597
Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
++ + W EP S+GGSPIT+Y +E + K W
Sbjct: 598 AKQDEEGWIVTWKEPMSDGGSPITSYAVETRINKTAEW 635
Score = 34.7 bits (76), Expect = 0.73
Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 2/78 (2%)
Query: 1638 SHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGPVIMR-EISRESVTIEWKPPLDDGG 1695
+++ YTI+ A +++ + K P P + + E + WK P+ DGG
Sbjct: 558 TYTGTYTIDGKVLAFKEDYLQLPQQARTKAGVPTAPQFVEAKQDEEGWIVTWKEPMSDGG 617
Query: 1696 LELTKYAIEKHEPDNNRW 1713
+T YA+E W
Sbjct: 618 SPITSYAVETRINKTAEW 635
>U64858-1|AAN84864.1| 2456|Caenorhabditis elegans Roller: helically
twisted, animalsroll when moving protein 3, isoform a
protein.
Length = 2456
Score = 40.7 bits (91), Expect = 0.011
Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 15/98 (15%)
Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT--LTPPSQPRN---------FVV 1874
I L T+Y +R A GT YT D K+ K L P Q R FV
Sbjct: 1688 ITNLLSATSYDYRFVA-TYTGT---YTIDGKVLAFKEDYLQLPQQARTKAGVPTAPQFVE 1743
Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
++ + W EP S+GGSPIT+Y +E + K W
Sbjct: 1744 AKQDEEGWIVTWKEPMSDGGSPITSYAVETRINKTAEW 1781
Score = 34.7 bits (76), Expect = 0.73
Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 2/78 (2%)
Query: 1638 SHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGPVIMR-EISRESVTIEWKPPLDDGG 1695
+++ YTI+ A +++ + K P P + + E + WK P+ DGG
Sbjct: 1704 TYTGTYTIDGKVLAFKEDYLQLPQQARTKAGVPTAPQFVEAKQDEEGWIVTWKEPMSDGG 1763
Query: 1696 LELTKYAIEKHEPDNNRW 1713
+T YA+E W
Sbjct: 1764 SPITSYAVETRINKTAEW 1781
>U39651-5|AAL11482.2| 395|Caenorhabditis elegans Temporarily
assigned gene nameprotein 22, isoform a protein.
Length = 395
Score = 40.7 bits (91), Expect = 0.011
Identities = 19/58 (32%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDEN 478
D V Y Y+A+ ++ + + + ERL +LD S ++WW V + G+VP+ Y+ E+
Sbjct: 4 DYVVVKYDYLAQEEQELTIKKNERLKLLDDS-KNWWKVMND-SNSVGFVPSNYVRKES 59
Score = 38.3 bits (85), Expect = 0.059
Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 421 DTVFAVYSYVAETDEAINLVEGERLYILD--TSNQDWWYVQKHLTEEKGWVPAQYL 474
+ V A+YS+ A + E ++ +GERL I+D + DWW + ++ + G VP Y+
Sbjct: 214 EVVVALYSFDASSSEELSFKKGERLEIVDHPEHDPDWW-MARNASGTTGLVPRNYI 268
Score = 31.9 bits (69), Expect = 5.2
Identities = 11/48 (22%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 427 YSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL 474
++Y ++ + L +G+ +Y+++ S WW + GW P+ Y+
Sbjct: 123 FTYEPRLEDELGLTKGDFVYVVEKSTDGWWKGEAP-NGGVGWFPSNYV 169
>AF188751-1|AAF00548.1| 1083|Caenorhabditis elegans tyrosine kinase
receptor T17A3.1 protein.
Length = 1083
Score = 40.7 bits (91), Expect = 0.011
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 13/195 (6%)
Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV-- 1191
DAL+ + K+ +I DG ++ Y L + C VGN + V
Sbjct: 501 DALLEYRKENFKIFTKVSRSFVADGTFERKISYQVVLTENMMLKCRVGNRVALETVHVAD 560
Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDET--LDVTW-YKKKSVIEDTEKFTLISDV 1248
E P+I F L + + +T LT +P +TW ++ S++ TE +
Sbjct: 561 EIPNIKFKLASNKSAIYEGDT-VKLTCVVPKLAGRCSITWVHRNLSILHSTE---VTEHS 616
Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDY--EREYRIKRGSDVT 1306
+ L IR T YTCVL + S +++ P I Y + + GS +
Sbjct: 617 QLSFLYIRNATTSASGNYTCVLENQASENFSLSTILKVEPIIAPYIVKTGFSAPTGSKLD 676
Query: 1307 LLVDYQAFPQPNDEW 1321
+D + P P +W
Sbjct: 677 CNIDGR--PPPEYQW 689
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 22/120 (18%)
Query: 479 NYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538
NYT L+ + +E + + E +AP V+ P GS + +C ++G P
Sbjct: 633 NYTCVLENQASENFSLSTILKV----EPIIAPYIVKT--GFSAPTGS--KLDCNIDGRPP 684
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
P+ WF+ + + ++++DN +G + C+A N AG A+++ EL
Sbjct: 685 PEYQWFKDGTPYGTGRRLK-FFEEDN-------------SGIYQCLATNRAGSATNSFEL 730
Score = 33.5 bits (73), Expect = 1.7
Identities = 31/161 (19%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 1497 EDIELTCIFGGVP-QPKVTW-YRDGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCIAF 1553
+ ++LTC+ + + +TW +R+ L + + T ++ Y C+
Sbjct: 580 DTVKLTCVVPKLAGRCSITWVHRNLSILHSTEVTEHSQLSFLYIRNATTSASGNYTCVLE 639
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
N E + + ++ +P+I + +K + I+G PPPE W+K+G
Sbjct: 640 NQASENFSLSTI-LKVEPII--APYIVKTGFSAPTGSKLDCNIDGRPPPEYQWFKDGTPY 696
Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
+ ++ + + + R+ S+ + E TAG S
Sbjct: 697 GTGRRLKFFEEDNSGIYQCLATNRAGSATNSFEL-KTAGRS 736
Score = 31.1 bits (67), Expect = 9.0
Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Query: 1074 LYIRNTSVHDEGEYSCILRDESCT--AEVTVVELPPEIITRLQNQ--KVNKGNKATFEIE 1129
LYIRN + G Y+C+L +++ + T++++ P I + G+K I+
Sbjct: 621 LYIRNATTSASGNYTCVLENQASENFSLSTILKVEPIIAPYIVKTGFSAPTGSKLDCNID 680
Query: 1130 LTKGDALVRWFKDGS 1144
+ +WFKDG+
Sbjct: 681 -GRPPPEYQWFKDGT 694
>AF078787-11|AAC26948.2| 1083|Caenorhabditis elegans Vegf (vascular
endothelial growthfactor) receptor family protein 1
protein.
Length = 1083
Score = 40.7 bits (91), Expect = 0.011
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 13/195 (6%)
Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV-- 1191
DAL+ + K+ +I DG ++ Y L + C VGN + V
Sbjct: 501 DALLEYRKENFKIFTKVSRSFVADGTFERKISYQVVLTENMMLKCRVGNRVALETVHVAD 560
Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDET--LDVTW-YKKKSVIEDTEKFTLISDV 1248
E P+I F L + + +T LT +P +TW ++ S++ TE +
Sbjct: 561 EIPNIKFKLASNKSAIYEGDT-VKLTCVVPKLAGRCSITWVHRNLSILHSTE---VTEHS 616
Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDY--EREYRIKRGSDVT 1306
+ L IR T YTCVL + S +++ P I Y + + GS +
Sbjct: 617 QLSFLYIRNATTSASGNYTCVLENQASENFSLSTILKVEPIIAPYIVKTGFSAPTGSKLD 676
Query: 1307 LLVDYQAFPQPNDEW 1321
+D + P P +W
Sbjct: 677 CNIDGR--PPPEYQW 689
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 22/120 (18%)
Query: 479 NYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538
NYT L+ + +E + + E +AP V+ P GS + +C ++G P
Sbjct: 633 NYTCVLENQASENFSLSTILKV----EPIIAPYIVKT--GFSAPTGS--KLDCNIDGRPP 684
Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
P+ WF+ + + ++++DN +G + C+A N AG A+++ EL
Sbjct: 685 PEYQWFKDGTPYGTGRRLK-FFEEDN-------------SGIYQCLATNRAGSATNSFEL 730
Score = 33.5 bits (73), Expect = 1.7
Identities = 31/161 (19%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 1497 EDIELTCIFGGVP-QPKVTW-YRDGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCIAF 1553
+ ++LTC+ + + +TW +R+ L + + T ++ Y C+
Sbjct: 580 DTVKLTCVVPKLAGRCSITWVHRNLSILHSTEVTEHSQLSFLYIRNATTSASGNYTCVLE 639
Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
N E + + ++ +P+I + +K + I+G PPPE W+K+G
Sbjct: 640 NQASENFSLSTI-LKVEPII--APYIVKTGFSAPTGSKLDCNIDGRPPPEYQWFKDGTPY 696
Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
+ ++ + + + R+ S+ + E TAG S
Sbjct: 697 GTGRRLKFFEEDNSGIYQCLATNRAGSATNSFEL-KTAGRS 736
Score = 31.1 bits (67), Expect = 9.0
Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Query: 1074 LYIRNTSVHDEGEYSCILRDESCT--AEVTVVELPPEIITRLQNQ--KVNKGNKATFEIE 1129
LYIRN + G Y+C+L +++ + T++++ P I + G+K I+
Sbjct: 621 LYIRNATTSASGNYTCVLENQASENFSLSTILKVEPIIAPYIVKTGFSAPTGSKLDCNID 680
Query: 1130 LTKGDALVRWFKDGS 1144
+ +WFKDG+
Sbjct: 681 -GRPPPEYQWFKDGT 694
>AC006607-2|AAF60372.1| 137|Caenorhabditis elegans One ig domain
protein 1 protein.
Length = 137
Score = 40.7 bits (91), Expect = 0.011
Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
Query: 810 SEGI-AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
S GI A++S + ++ N P + + + + + +KL + NP P I WY
Sbjct: 18 SVGINAKSSHIEDLDFTDHTNGSPKISRSSYFKQDFRLGYKLKLFCESSGNPRPQIVWYH 77
Query: 869 NNEIISP--SETITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAG 913
++P + TI + G+ + + + I D G+Y+CVA+N G
Sbjct: 78 RGVEVNPDHNRTIRFSIHGDTVSSHLEVDPTSIGDKGEYECVATNLKG 125
Score = 37.5 bits (83), Expect = 0.10
Identities = 20/70 (28%), Positives = 29/70 (41%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
G + L C P P I W +G E+ PD N ++ S L++ +G
Sbjct: 56 GYKLKLFCESSGNPRPQIVWYHRGVEVNPDHNRTIRFSIHGDTVSSHLEVDPTSIGDKGE 115
Query: 708 YTVVAVNREG 717
Y VA N +G
Sbjct: 116 YECVATNLKG 125
Score = 37.1 bits (82), Expect = 0.14
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD--DDNVAT-LVIREVFPEDAGT 580
G ++ C+ G PRPQI W+ + + P + + + D V++ L + D G
Sbjct: 56 GYKLKLFCESSGNPRPQIVWYHRGVEVNPDHNRTIRFSIHGDTVSSHLEVDPTSIGDKGE 115
Query: 581 FTCVAKNAAG 590
+ CVA N G
Sbjct: 116 YECVATNLKG 125
>Z81568-14|CAB04591.2| 608|Caenorhabditis elegans Hypothetical
protein K08E3.3a protein.
Length = 608
Score = 40.3 bits (90), Expect = 0.015
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Query: 415 VEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQD-WWYVQKHLTEEKGWVPAQY 473
V+V TV A++ + + E +++ +GE L +L+ + D W +K EE G+VP Y
Sbjct: 544 VKVETAVTVTALFEFAKSSAETMSIEQGEILLVLEHDHGDGWTRTKKKHNEESGFVPTSY 603
Query: 474 L 474
L
Sbjct: 604 L 604
>AL032631-14|CAA21577.2| 220|Caenorhabditis elegans Hypothetical
protein Y106G6H.14 protein.
Length = 220
Score = 40.3 bits (90), Expect = 0.015
Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query: 425 AVYSYVAETDEAINLVEGERLYILDTS-NQDWWYVQKHLTEEKGWVPAQYLMDEN 478
A+Y + A + + + EG+ +Y+ D N+DW+ Q + +KG VPA Y++ EN
Sbjct: 24 ALYDFQARSAQELTFSEGDLMYVSDEQPNKDWF--QASIGGKKGLVPANYVISEN 76
>U23452-9|AAU87820.1| 155|Caenorhabditis elegans Hypothetical
protein R07G3.9 protein.
Length = 155
Score = 39.9 bits (89), Expect = 0.019
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMY---YDDDNV-ATLVIREVFPEDAGTFTCVAK 586
C+ G PRP I W+++ A I+P Y ++D + + L + D G + CVA
Sbjct: 80 CKARGDPRPTIKWYKEGAEIQPKASIHYYEKPIENDTIWSKLEVDPATMGDQGVYACVAN 139
Query: 587 NAAG 590
N G
Sbjct: 140 NPHG 143
Score = 33.9 bits (74), Expect = 1.3
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT------KSDGDT-HSITILKPK 795
S R G +++ + G+PRPTI W K ++ + + DT S + P
Sbjct: 67 SQTYRLGYKLLIICKARGDPRPTIKWYKEGAEIQPKASIHYYEKPIENDTIWSKLEVDPA 126
Query: 796 KVKDEGVYTLKAENSEGI 813
+ D+GVY A N G+
Sbjct: 127 TMGDQGVYACVANNPHGV 144
Score = 32.3 bits (70), Expect = 3.9
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENI---SVAIESDMHMYCSVLKITNVKKFQ 704
G +L+ C+ P P I W +G EI P +I IE+D S L++
Sbjct: 73 GYKLLIICKARGDPRPTIKWYKEGAEIQPKASIHYYEKPIEND--TIWSKLEVDPATMGD 130
Query: 705 EGTYTVVAVNREG 717
+G Y VA N G
Sbjct: 131 QGVYACVANNPHG 143
>AF039712-1|AAK21402.2| 239|Caenorhabditis elegans 2 (zwei)
ig-domain protein protein7 protein.
Length = 239
Score = 39.9 bits (89), Expect = 0.019
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 7/83 (8%)
Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888
NA PP I + E+ + L V NP P + W +N E + S++I +DG N+
Sbjct: 141 NARPPHVIGAERRGLHGER--MVLECPVLANPEPMVRWEKNGEPLGNSDSI--EYDGNNL 196
Query: 889 ELVITNVDSEIDSGDYKCVASNS 911
I N +E G Y+C+ NS
Sbjct: 197 ---ILNSLTEDHIGKYRCIGDNS 216
Score = 33.5 bits (73), Expect = 1.7
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
PP VI + + GE ++L V+ NP P + W KN +P+
Sbjct: 144 PPHVIGAERRGL--HGERMVLECPVLANPEPMVRWEKNGEPL 183
>Z81568-15|CAB04595.2| 610|Caenorhabditis elegans Hypothetical
protein K08E3.3b protein.
Length = 610
Score = 38.3 bits (85), Expect = 0.059
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 415 VEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHL---TEEKGWVPA 471
V+V TV A++ + + E +++ +GE L +L+ + D W K+ EE G+VP
Sbjct: 544 VKVETAVTVTALFEFAKSSAETMSIEQGEILLVLEHDHGDGWTRTKNCRKHNEESGFVPT 603
Query: 472 QYL 474
YL
Sbjct: 604 SYL 606
>Z81085-3|CAB03115.1| 769|Caenorhabditis elegans Hypothetical
protein F46F3.4 protein.
Length = 769
Score = 37.9 bits (84), Expect = 0.078
Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 5/77 (6%)
Query: 423 VFAVYSYVAETDEAINLVEGERLYIL--DTSNQDWWYVQKHLTEEKGWVPAQYLMDENNY 480
V+A Y Y A ++ ++ G+ L ++ D +++WW +K+ EKG VP YL +
Sbjct: 689 VYAAYGYEAAFEDELSFDAGDELTVIEKDKVDKNWWTCEKN-NGEKGQVPRTYLALYPS- 746
Query: 481 TQYLQKKLNEKIDKLPV 497
+Y +KKLN + LP+
Sbjct: 747 LKY-RKKLNFVMFDLPL 762
>U28409-1|AAC46592.3| 231|Caenorhabditis elegans Hypothetical
protein T25D10.2 protein.
Length = 231
Score = 37.9 bits (84), Expect = 0.078
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 10/123 (8%)
Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV-E 534
DE NY Y Q++ + K + VF+ + ++ KL P G ++ C + +
Sbjct: 101 DEGNY--YCQRENDSKWGE--VFQLKIAYVDEISQNEKIKLEPNVPTLGRSLVLHCPIPK 156
Query: 535 GYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
YP P++TW I S D+ + + TL+I G F C N AG AS
Sbjct: 157 AYPPPKVTWTVNSLPISHISSDYVAFPN----GTLIISHFSYHHFGYFECNINNFAGHAS 212
Query: 594 STT 596
+ T
Sbjct: 213 TNT 215
Score = 31.1 bits (67), Expect = 9.0
Identities = 30/133 (22%), Positives = 51/133 (38%), Gaps = 6/133 (4%)
Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK--SMIVRQGESV 752
L I +V+K EG Y RE ++ V ++K + E +K + G S+
Sbjct: 92 LVIFDVQKEDEGNYYC---QRENDSKWGEVFQLKIAYVDEISQNEKIKLEPNVPTLGRSL 148
Query: 753 ILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
+L + P P +TW N+ P+ + + + I+ G + N
Sbjct: 149 VLHCPIPKAYPPPKVTWTVNSLPISHISSDYVAFPNGTLIISHFSYHHFGYFECNINNFA 208
Query: 812 GIAETSAVITVEE 824
G A T+ I E
Sbjct: 209 GHASTNTFIDSRE 221
>AF134186-1|AAD55361.1| 1359|Caenorhabditis elegans XNP-1 protein.
Length = 1359
Score = 37.9 bits (84), Expect = 0.078
Identities = 24/107 (22%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEK 208
E+ ++++ + +++ KP + + + ++AKSE + E E+ + K+ + +V +K
Sbjct: 173 EKSVKKRAETSEESDEDEKPS-KKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKK 231
Query: 209 INVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQ 255
+ +D+ + T KRSK + E E E S + E P+
Sbjct: 232 ESESEDEAPEKKKTEKRKRSKTS--SEESSESEKSDEEEEEKESSPK 276
Score = 32.3 bits (70), Expect = 3.9
Identities = 48/260 (18%), Positives = 93/260 (35%), Gaps = 15/260 (5%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEK 208
ER L + +E E KP + P + + SE +E E P + S + K
Sbjct: 30 ERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDDDEEESP--RKSSKKSRKRAK 87
Query: 209 INVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXX 268
D+ + +K K K + K + T +E D +
Sbjct: 88 SESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKT 147
Query: 269 XXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVF 328
+TS + + + ++K +S+K ++ S+ K+ K K
Sbjct: 148 KKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKK---- 203
Query: 329 VPPKLPDVEKTELEQPLFSYEDIVESKKDENEII-QEKQTLEELPKEDVPEQYTITPRKS 387
K+E E +++ +SKK +++ +E ++ +E P++ E+ + S
Sbjct: 204 --------AKSESESESEDEKEVKKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSS 255
Query: 388 SAQKIDEIVDEVTIKKRLNP 407
E DE +K +P
Sbjct: 256 EESSESEKSDEEEEEKESSP 275
>AF000196-11|AAC24256.1| 1359|Caenorhabditis elegans Human xnp gene
related protein 1 protein.
Length = 1359
Score = 37.9 bits (84), Expect = 0.078
Identities = 24/107 (22%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEK 208
E+ ++++ + +++ KP + + + ++AKSE + E E+ + K+ + +V +K
Sbjct: 173 EKSVKKRAETSEESDEDEKPS-KKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKK 231
Query: 209 INVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQ 255
+ +D+ + T KRSK + E E E S + E P+
Sbjct: 232 ESESEDEAPEKKKTEKRKRSKTS--SEESSESEKSDEEEEEKESSPK 276
Score = 32.3 bits (70), Expect = 3.9
Identities = 48/260 (18%), Positives = 93/260 (35%), Gaps = 15/260 (5%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEK 208
ER L + +E E KP + P + + SE +E E P + S + K
Sbjct: 30 ERKEKRAQKLKEKREREGKPPPKKRPAKKRKASSSEEDDDDEEESP--RKSSKKSRKRAK 87
Query: 209 INVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXX 268
D+ + +K K K + K + T +E D +
Sbjct: 88 SESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSKKT 147
Query: 269 XXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVF 328
+TS + + + ++K +S+K ++ S+ K+ K K
Sbjct: 148 KKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKK---- 203
Query: 329 VPPKLPDVEKTELEQPLFSYEDIVESKKDENEII-QEKQTLEELPKEDVPEQYTITPRKS 387
K+E E +++ +SKK +++ +E ++ +E P++ E+ + S
Sbjct: 204 --------AKSESESESEDEKEVKKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSS 255
Query: 388 SAQKIDEIVDEVTIKKRLNP 407
E DE +K +P
Sbjct: 256 EESSESEKSDEEEEEKESSP 275
>U39651-6|AAL11483.1| 286|Caenorhabditis elegans Temporarily
assigned gene nameprotein 22, isoform b protein.
Length = 286
Score = 37.5 bits (83), Expect = 0.10
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
Query: 423 VFAVYSYVAETDEAINLVEGERLYILD--TSNQDWWYVQKHLTEEKGWVPAQYL 474
V A+YS+ A + E ++ +GERL I+D + DWW + ++ + G VP Y+
Sbjct: 106 VVALYSFDASSSEELSFKKGERLEIVDHPEHDPDWW-MARNASGTTGLVPRNYI 158
Score = 31.9 bits (69), Expect = 5.2
Identities = 11/48 (22%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 427 YSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYL 474
++Y ++ + L +G+ +Y+++ S WW + GW P+ Y+
Sbjct: 11 FTYEPRLEDELGLTKGDFVYVVEKSTDGWWKGEAP-NGGVGWFPSNYV 57
>AF026215-7|AAB71317.1| 415|Caenorhabditis elegans Hypothetical
protein F09G2.9 protein.
Length = 415
Score = 37.5 bits (83), Expect = 0.10
Identities = 18/81 (22%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219
+SQ+DE D P + EA E ++EE ++ + + + E+ P++K++ +
Sbjct: 81 ESQKDEKTDDAPAEPAEVAVEAAKEEPVVEEKKEDAPEPVVTEEKKSEEAPAPEEKKSEE 140
Query: 220 TPTSFNKRSKLTPIKIERKEM 240
+ K+ ++ E+KE+
Sbjct: 141 VVAAEEKKEPAAVVE-EKKEV 160
Score = 31.9 bits (69), Expect = 5.2
Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 6/90 (6%)
Query: 160 DSQEDESKPDVSQPPQN----IIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDK 215
+ +ED +P V++ ++ EE KSE + E ++ A E EVPE V D K
Sbjct: 111 EKKEDAPEPVVTEEKKSEEAPAPEEKKSEEVVAAEEKKEPAAVVEEKKEVPETPVVEDKK 170
Query: 216 ETSQTPTSFNKRSKLTPIKIERKEMEVSTP 245
E + P S ++ + E K+ P
Sbjct: 171 E--EAPASSEEKKDEPVVNTEEKKDAAEAP 198
>Z72518-2|CAA96700.1| 613|Caenorhabditis elegans Hypothetical protein
ZC374.2 protein.
Length = 613
Score = 37.1 bits (82), Expect = 0.14
Identities = 64/291 (21%), Positives = 110/291 (37%), Gaps = 20/291 (6%)
Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI---MREISRESVTIEWK-PPLD 1692
RS +S+ TI S+TA S VE+T+ D + +I R ++ V + W+ PP
Sbjct: 265 RSATSQDTI--SSTA--SIVEITMPREDDYFEIGNLIISSHFRTATQGIVNLTWEVPPTM 320
Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
++ Y +E E N+R+ + + + L N EY+ R+ + + +
Sbjct: 321 QN--KIVAYNVEYSEMGNSRYWQKIQFHGASSSAALHHLKSNTEYLLRI--KTTLANNIV 376
Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE--- 1809
ES +T + D SV + W + Y V + Q+
Sbjct: 377 TESGQFRFRTPRVETNPINKVDVIYSHDVNSVKLQWMLEPHIRQENVAGYDVYLSQDKDL 436
Query: 1810 -GKKWK-XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI-TIGKTLTPP 1866
+WK ++ L +T Y R+ RN G+ + S + TI T
Sbjct: 437 PDSQWKLVRLNNRESHLSLEDLKSSTIYFVRVNVRNTDGSVIRAPSVYRFKTIDNTDEEE 496
Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII--EFKTVKGKSWTKI 1915
+ + V ++WT P+S S I I+ K + + W KI
Sbjct: 497 FEGNSLAYRNVAPGEVEIRWTFPKSILDSVIGATILYTNRKDLTPEQWQKI 547
Score = 36.3 bits (80), Expect = 0.24
Identities = 68/293 (23%), Positives = 111/293 (37%), Gaps = 28/293 (9%)
Query: 1784 VYITWF--PSEKNGGSPIIDYKVEIKQEGKK--W-KXXXXXXXXXARIQKLSINTTYQFR 1838
V +TW P+ +N I+ Y VE + G W K A + L NT Y R
Sbjct: 310 VNLTWEVPPTMQN---KIVAYNVEYSEMGNSRYWQKIQFHGASSSAALHHLKSNTEYLLR 366
Query: 1839 IYARNEIGTSLPYTSDD-KITIGKTLTPPSQPRNFVVSESTSRSVTLKWT-EP----ESN 1892
I + + ++ S + + T P + + S + SV L+W EP E+
Sbjct: 367 I--KTTLANNIVTESGQFRFRTPRVETNPINKVDVIYSHDVN-SVKLQWMLEPHIRQENV 423
Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
G + Y+ + K + W K+V + +E++K R++ NT G +
Sbjct: 424 AGYDV--YLSQDKDLPDSQW-KLVRLNNRESHLSLEDLKSSTIYFVRVNVRNTDGSVIRA 480
Query: 1953 ES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE--WDG--GAPLLGYNIAIRD 2007
S + + L R V V W P+ D GA +L N +D
Sbjct: 481 PSVYRFKTIDNTDEEEFEGNSLAYRNVAPGEVEIRWTFPKSILDSVIGATILYTNR--KD 538
Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
+T W ++ D ++ L+E Y ++I R G ES E F+
Sbjct: 539 LTPEQWQKIEIEDSKNTTVLLKHLTEGVRYSVQIIPRLYTG-DYDFESRELFE 590
>AC087794-1|AAG53701.2| 304|Caenorhabditis elegans Hypothetical
protein Y32G9A.8 protein.
Length = 304
Score = 37.1 bits (82), Expect = 0.14
Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 5/68 (7%)
Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
+ P S + +C + GYP PQI W++ ++ + L I EDAG
Sbjct: 161 YAPLDSAARIQCPIVGYPEPQIVWYKDKFPLEIEGRVKF-----TAGVLSIEGAQEEDAG 215
Query: 580 TFTCVAKN 587
+ C A N
Sbjct: 216 VYRCEATN 223
Score = 32.3 bits (70), Expect = 3.9
Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785
++K E EP V+ P ++ + + +VG P P I W K+ P++
Sbjct: 144 ELKKSESEPFTVVGP--AVYAPLDSAARIQCPIVGYPEPQIVWYKDKFPLEIEGRVK--F 199
Query: 786 THSITILKPKKVKDEGVYTLKAEN 809
T + ++ + +D GVY +A N
Sbjct: 200 TAGVLSIEGAQEEDAGVYRCEATN 223
>AL110485-5|CAB60375.1| 1002|Caenorhabditis elegans Hypothetical
protein Y46G5A.6 protein.
Length = 1002
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 179 EEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRS-KLTPIKIER 237
+E K + KL E+ + +A + E+ E PE + D+++ +TP +RS + + +R
Sbjct: 575 QERKKKEKLKEKERELLAVSDEVKKEEPESSDEDDNRKDQRTPREDRRRSVERQDQREDR 634
Query: 238 KEMEVSTPQHAETVDGPQ 255
KE S AE P+
Sbjct: 635 KERIKSPDDRAERRRSPE 652
>Z49131-3|CAA88976.1| 1211|Caenorhabditis elegans Hypothetical protein
ZC373.4 protein.
Length = 1211
Score = 36.3 bits (80), Expect = 0.24
Identities = 61/261 (23%), Positives = 109/261 (41%), Gaps = 21/261 (8%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKL----IEESEQPIAKTSEIDNE 204
E+V +K L ++D+S D + P IIE+ S PKL + +P+ KTS+I
Sbjct: 780 EKVLTKKKSL---KKDKSIDD--RLPVKIIEDKASLPKLKTDVVTFESKPVKKTSKIVKL 834
Query: 205 VPEKIN-VPDDKETSQTPTSFNKRSKLT-PIKIERKEMEVSTPQHAE-TVDGPQFXXXXX 261
+PE N + D+K+ ++ + K++ T K S+ + E T DG +
Sbjct: 835 IPEDANLIKDEKKPTKIVMTSEKQATTTVQTTTSVKRTTKSSEKKVEHTADG-KSVESSQ 893
Query: 262 XXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAA 321
+ S V K + ++ + +K S K++ + N ++
Sbjct: 894 KKNSQKDDVKVSQVTTKKEEDSTQPAPTLTVKKNVVKQTAEKSTSEKEHK-TTENKEQER 952
Query: 322 KVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYT 381
+KK + K DV + L+Q + + K E+++I K + +L + E
Sbjct: 953 IIKKSSTLKDK--DVAQVSLQQSI----KVNGEKHKESKVIGTKTVINKLELKG-EETIN 1005
Query: 382 ITPRKSSAQKIDEIVDEVTIK 402
P+KSS +K V T K
Sbjct: 1006 ANPKKSSLKKATAKVTGETTK 1026
>AL110484-6|CAE46683.1| 1345|Caenorhabditis elegans Hypothetical
protein Y38E10A.6b protein.
Length = 1345
Score = 36.3 bits (80), Expect = 0.24
Identities = 40/162 (24%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 307 IKQNGILSRNIKEAAKV--KKQV---FVPPKLPDVEKTE-LEQPLFSYEDIVESKKDENE 360
+K+NG + I E A++ KK V + L +K+E + + E+I ES K +
Sbjct: 884 LKKNGSETAEIAEKAQISEKKPVNRLVIDEVLKSPQKSEKIPEKAQEIEEIEESPKKSEK 943
Query: 361 IIQEKQTLEELPKE-----DVPEQYTITPRKS-SAQKIDEI--VDEVTIKKR--LNPFEI 410
++ Q ++E+PK+ + P++ +P+KS Q+I EI E T +KR +
Sbjct: 944 APEKPQEIQEIPKKSEKAPEKPQEIEKSPKKSEKRQEIQEIPQKSEKTSEKRPEIEELPT 1003
Query: 411 FYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSN 452
F+ + + A+ + +N V E ++ D +N
Sbjct: 1004 FFKSSAPAQTPEIISDEDIFAQYESLLNAVFSEFQFVDDRTN 1045
>AL110484-5|CAB60334.3| 1343|Caenorhabditis elegans Hypothetical
protein Y38E10A.6a protein.
Length = 1343
Score = 36.3 bits (80), Expect = 0.24
Identities = 40/162 (24%), Positives = 75/162 (46%), Gaps = 16/162 (9%)
Query: 307 IKQNGILSRNIKEAAKV--KKQV---FVPPKLPDVEKTE-LEQPLFSYEDIVESKKDENE 360
+K+NG + I E A++ KK V + L +K+E + + E+I ES K +
Sbjct: 882 LKKNGSETAEIAEKAQISEKKPVNRLVIDEVLKSPQKSEKIPEKAQEIEEIEESPKKSEK 941
Query: 361 IIQEKQTLEELPKE-----DVPEQYTITPRKS-SAQKIDEI--VDEVTIKKR--LNPFEI 410
++ Q ++E+PK+ + P++ +P+KS Q+I EI E T +KR +
Sbjct: 942 APEKPQEIQEIPKKSEKAPEKPQEIEKSPKKSEKRQEIQEIPQKSEKTSEKRPEIEELPT 1001
Query: 411 FYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSN 452
F+ + + A+ + +N V E ++ D +N
Sbjct: 1002 FFKSSAPAQTPEIISDEDIFAQYESLLNAVFSEFQFVDDRTN 1043
>Z81077-4|CAB03071.3| 618|Caenorhabditis elegans Hypothetical protein
F36A2.4 protein.
Length = 618
Score = 35.9 bits (79), Expect = 0.32
Identities = 46/191 (24%), Positives = 77/191 (40%), Gaps = 13/191 (6%)
Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
PP P + V +++ SV L W P S P Y I ++ +K K+ + G +
Sbjct: 388 PPDPPSDCQVVSTSAYSVRLAWAPPFS--PDPDLTYNIRYR-LKHNEDAKVRELRG-IKG 443
Query: 1925 HCIE--NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
+ +E ++ FRI+A N G ES++V L ++ P L R+ +N
Sbjct: 444 NTVEIMSVDSCSLYEFRITAHNKFG-----ESKAVYLVQYTEPQLSPQHILATRL-NANT 497
Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
+ +W P + + Y + + E K+ VN + DL + YM
Sbjct: 498 IELTW-EPPYKKSHEVKNYVVYFTENPNASLSEWEKIPVNGRRVVFPDLRFDWFYMFSAT 556
Query: 2043 ARNEIGLSEPL 2053
A + G PL
Sbjct: 557 AVFKDGQRSPL 567
>U41110-3|AAA82418.1| 170|Caenorhabditis elegans Helix loop helix
protein 10 protein.
Length = 170
Score = 35.9 bits (79), Expect = 0.32
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 2/64 (3%)
Query: 175 QNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIK 234
Q+++E + S+P+L ++ E P T E D K V D+ E++ +PT N R + + K
Sbjct: 21 QSMLEASASQPQLTQD-EPPENDTKENDLVKQNKSEVNDENESTPSPTQ-NSRRRTSTGK 78
Query: 235 IERK 238
I+R+
Sbjct: 79 IDRR 82
>AF101310-1|AAC69216.2| 765|Caenorhabditis elegans Hypothetical
protein C39F7.2 protein.
Length = 765
Score = 35.9 bits (79), Expect = 0.32
Identities = 43/146 (29%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK-PEGPVI-MREISR 1680
TK +T + L H +YTI+ + A + + S+ P P+I E S
Sbjct: 453 TKPETDSEFVLNLDTKHL-QYTIQTLDFAQLKAGPRGTRFKGDASRVPSAPIIETSECSA 511
Query: 1681 E--SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEY 1737
E SVT+ W+P D ++ I+ D N +V +T C I L+ N Y
Sbjct: 512 ENNSVTVVWRPRNDGSAVDGFALEIDTGRDDGN----FKEVYSGPDTICTIDGLHFNTVY 567
Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTA 1763
RV + N G SE SE I ++TA
Sbjct: 568 AARVKSYNSAGESE--YSESICLQTA 591
Score = 33.9 bits (74), Expect = 1.3
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 4/85 (4%)
Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXX 1823
VPS +N SV + W P +N GS + + +EI ++ +K
Sbjct: 498 VPSAPIIETSECSAENNSVTVVWRP--RNDGSAVDGFALEIDTGRDDGNFKEVYSGPDTI 555
Query: 1824 ARIQKLSINTTYQFRIYARNEIGTS 1848
I L NT Y R+ + N G S
Sbjct: 556 CTIDGLHFNTVYAARVKSYNSAGES 580
>Z69646-2|CAA93475.1| 1087|Caenorhabditis elegans Hypothetical
protein F57C7.1b protein.
Length = 1087
Score = 35.1 bits (77), Expect = 0.55
Identities = 17/62 (27%), Positives = 30/62 (48%)
Query: 188 IEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQH 247
+EE E+PI + E+ ++ PE + D E+S + F K ++ E + EV+
Sbjct: 181 MEEVEEPIVASEEVPDKKPESVKESTDSESSGSEHGFEKMDTAEKVEDECNDDEVAASNG 240
Query: 248 AE 249
E
Sbjct: 241 TE 242
>Z69646-1|CAA93473.3| 1209|Caenorhabditis elegans Hypothetical
protein F57C7.1a protein.
Length = 1209
Score = 35.1 bits (77), Expect = 0.55
Identities = 17/62 (27%), Positives = 30/62 (48%)
Query: 188 IEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQH 247
+EE E+PI + E+ ++ PE + D E+S + F K ++ E + EV+
Sbjct: 181 MEEVEEPIVASEEVPDKKPESVKESTDSESSGSEHGFEKMDTAEKVEDECNDDEVAASNG 240
Query: 248 AE 249
E
Sbjct: 241 TE 242
>U64834-2|AAB04823.2| 1145|Caenorhabditis elegans Hypothetical
protein F54D11.2 protein.
Length = 1145
Score = 35.1 bits (77), Expect = 0.55
Identities = 47/228 (20%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-NKPVKALPTKSDGD 785
+K EKE + P ++ +V +P I + P K+ PT +
Sbjct: 184 VKKPEKEAEALAPPEPPAEPQEAAETPAPEPLVPEKKPKIEDAPTTSSPKKSTPTSAPPT 243
Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAV--ITVEEPTEENAEPPLFINRFQEIT 843
S + KP ++ +G + + I E + V +E T E A+ PL R +
Sbjct: 244 RASARVSKPNRLYADGSFNTEILGRTRITEQNPVKEAQAKESTPELADLPLPAGRRKSTA 303
Query: 844 VKE----KGTIKLVARVTRNPVPSI-----TWYRNNEIISPSETITQNFDGENIELVITN 894
I ++ V R +PS+ + + EII+ +E + + D ++
Sbjct: 304 APRAPPAPKPIPVINGVLRGYIPSVKVPLAEYEVDGEIINLNEGVNETMDTILAKVCEDG 363
Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
V+ D D K V + K + R+ + V+K+ ++ EE
Sbjct: 364 VEKHEDI-DPKVVKAKKLAKIDYTKRLKLQVKKLDIQMRIKIPSTPEE 410
>Z79756-4|CAB02119.1| 550|Caenorhabditis elegans Hypothetical protein
F53C11.6 protein.
Length = 550
Score = 34.7 bits (76), Expect = 0.73
Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
T Y+F +Y G S+P I + + P + P++ + + + T+ W P+ N
Sbjct: 455 TLYEFSVYVTTRYGQSVP------IKVQEYTEPCTVPQSVRIDAISDETATISWRAPKMN 508
Query: 1893 GGSPITNYIIEF 1904
G +Y+I+F
Sbjct: 509 NGP--ESYVIQF 518
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/131 (22%), Positives = 50/131 (38%), Gaps = 7/131 (5%)
Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG-SVHE 1924
P PR+ + S +T+ SV L+W+ P Y I +K + +V V +
Sbjct: 386 PDPPRHLIASHATADSVMLRWSAPIYVDEGKRYWYTITYKPRTPQRRNNVVAVDFINKDR 445
Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
+ + +K F + G S+P + Q + TVP + I +
Sbjct: 446 YLVTGLKSFTLYEFSVYVTTRYGQSVPIKVQ--EYTEPCTVPQ----SVRIDAISDETAT 499
Query: 1985 TSWGTPEWDGG 1995
SW P+ + G
Sbjct: 500 ISWRAPKMNNG 510
>Z78066-6|CAB51467.1| 2484|Caenorhabditis elegans Hypothetical protein
W06A7.3c protein.
Length = 2484
Score = 34.7 bits (76), Expect = 0.73
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 154 EKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDN---EVPEKIN 210
E+ + D Q P Q + E EP+ ++E E+P+ E DN E PE IN
Sbjct: 1717 EEVPMMDMQSVPHSPQEKQEEIEALSEIIEEPQAMKEVEKPVESAPEKDNESLEAPEIIN 1776
Query: 211 VP 212
P
Sbjct: 1777 EP 1778
>Z78066-4|CAB01522.2| 2607|Caenorhabditis elegans Hypothetical protein
W06A7.3a protein.
Length = 2607
Score = 34.7 bits (76), Expect = 0.73
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 154 EKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDN---EVPEKIN 210
E+ + D Q P Q + E EP+ ++E E+P+ E DN E PE IN
Sbjct: 1717 EEVPMMDMQSVPHSPQEKQEEIEALSEIIEEPQAMKEVEKPVESAPEKDNESLEAPEIIN 1776
Query: 211 VP 212
P
Sbjct: 1777 EP 1778
>Z70286-5|CAB61016.1| 3704|Caenorhabditis elegans Hypothetical protein
K08C7.3a protein.
Length = 3704
Score = 34.7 bits (76), Expect = 0.73
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE---PPLFI 836
D + + T PK D V L + E T+ T EEPTEE AE PP+ +
Sbjct: 3240 DENISTTTTAAPKPTDDSDVAVLPIDEEEESTTTTTTTTTEEPTEEPAEMRDPPVTV 3296
>U50071-2|AAA93447.2| 6994|Caenorhabditis elegans Uncoordinated
protein 44, isoform f protein.
Length = 6994
Score = 34.7 bits (76), Expect = 0.73
Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 9/120 (7%)
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
+ E+ V + E+E+ ++E T+ TV+ ++Y ++ E+ DH + E R
Sbjct: 3641 VATEEHEHVSSTKSDDESEQHVPSVIETTTTTTVTREFYDDQDELQREDHTQ--SEERRS 3698
Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEI 1040
D +IK + T+T V +E PE + KLQD + + +E EI
Sbjct: 3699 SIPTEETEHEDSHLIK-----ETTTTTTVTREFYDEPENVEKLQDSQFSLSPSSHVESEI 3753
>U39847-1|AAB41827.1| 6994|Caenorhabditis elegans AO13 ankyrin
protein.
Length = 6994
Score = 34.7 bits (76), Expect = 0.73
Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 9/120 (7%)
Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
+ E+ V + E+E+ ++E T+ TV+ ++Y ++ E+ DH + E R
Sbjct: 3641 VATEEHEHVSSTKSDDESEQHVPSVIETTTTTTVTREFYDDQDELQREDHTQ--SEERRS 3698
Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEI 1040
D +IK + T+T V +E PE + KLQD + + +E EI
Sbjct: 3699 SIPTEETEHEDSHLIK-----ETTTTTTVTREFYDEPENVEKLQDSQFSLSPSSHVESEI 3753
>D83173-1|BAA11828.1| 1518|Caenorhabditis elegans laminin A protein.
Length = 1518
Score = 34.7 bits (76), Expect = 0.73
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE---PPLFI 836
D + + T PK D V L + E T+ T EEPTEE AE PP+ +
Sbjct: 1054 DENISTTTTAAPKPTDDSDVAVLPIDEEEESTTTTTTTTTEEPTEEPAEMRDPPVTV 1110
>AL110487-14|CAB54429.2| 268|Caenorhabditis elegans Hypothetical
protein Y39E4B.8 protein.
Length = 268
Score = 34.7 bits (76), Expect = 0.73
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 19/147 (12%)
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVN--- 1119
+K +I L +R D G Y C + D+ T V+E P + LQ +
Sbjct: 95 KKSANIWVLNLRRAEQQDSGCYLCEINDKHNTVYAVYLKVLEPPLPSPSSLQKKSTKLMA 154
Query: 1120 --KGNKATFEIELTKGDAL-----VRWFKDGSEIQFSNHIQLTIDGKK------QKLKIY 1166
G++ +T D V W +DG+ I F++ + + K+ + ++I
Sbjct: 155 NMSGDEVVLNCTVTSTDKDEEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIR 214
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEE 1193
++D G Y+CE K + I+ + +
Sbjct: 215 KATMEDDGNYACEHSQQKASQIVHINK 241
Score = 32.7 bits (71), Expect = 3.0
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 1035 ILEVEINSETADVVWERDGEIIK-PKKNKYDFE-KRGH---IRKLYIRNTSVHDEGEYSC 1089
+ + + E DVVW RDG I KY + KR I + IR ++ D+G Y+C
Sbjct: 167 VTSTDKDEEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYAC 226
Score = 32.3 bits (70), Expect = 3.9
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 1222 DETLDVTWYKKKSVIE--DTEKFTLI----SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
+E LDV W + + I DTEK+ L + V T+ IRK T +D Y C K+
Sbjct: 174 EEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYACEHSQQKA 233
Query: 1276 TTKLKVEVVE 1285
+ + + E
Sbjct: 234 SQIVHINKAE 243
>AF456253-1|AAL59611.1| 268|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-8 protein.
Length = 268
Score = 34.7 bits (76), Expect = 0.73
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 19/147 (12%)
Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVN--- 1119
+K +I L +R D G Y C + D+ T V+E P + LQ +
Sbjct: 95 KKSANIWVLNLRRAEQQDSGCYLCEINDKHNTVYAVYLKVLEPPLPSPSSLQKKSTKLMA 154
Query: 1120 --KGNKATFEIELTKGDAL-----VRWFKDGSEIQFSNHIQLTIDGKK------QKLKIY 1166
G++ +T D V W +DG+ I F++ + + K+ + ++I
Sbjct: 155 NMSGDEVVLNCTVTSTDKDEEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIR 214
Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEE 1193
++D G Y+CE K + I+ + +
Sbjct: 215 KATMEDDGNYACEHSQQKASQIVHINK 241
Score = 32.7 bits (71), Expect = 3.0
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 1035 ILEVEINSETADVVWERDGEIIK-PKKNKYDFE-KRGH---IRKLYIRNTSVHDEGEYSC 1089
+ + + E DVVW RDG I KY + KR I + IR ++ D+G Y+C
Sbjct: 167 VTSTDKDEEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYAC 226
Score = 32.3 bits (70), Expect = 3.9
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 1222 DETLDVTWYKKKSVIE--DTEKFTLI----SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
+E LDV W + + I DTEK+ L + V T+ IRK T +D Y C K+
Sbjct: 174 EEVLDVVWTRDGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYACEHSQQKA 233
Query: 1276 TTKLKVEVVE 1285
+ + + E
Sbjct: 234 SQIVHINKAE 243
>AC024824-1|AAK85503.1| 679|Caenorhabditis elegans Hypothetical
protein Y55B1BR.3 protein.
Length = 679
Score = 34.7 bits (76), Expect = 0.73
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
Query: 318 KEAAKVKKQVFVPPKLPD--VEKTELEQPLFSYEDIVESKKDENEI----IQEKQTLEEL 371
+E +VKK P K P K E E+ E+ V KK ++I +E + EE
Sbjct: 341 EEVVEVKKNSKSPKKTPKKTAVKEESEESSGDEEEEVVKKKKSSKINKRKAKESSSDEEE 400
Query: 372 PKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTP 414
E+ P++ T +PRKSS + + E E+ Y+P
Sbjct: 401 EVEESPKKKTKSPRKSSKKSAAKEESEEESSDNEEEEEVDYSP 443
>AB016806-1|BAA32347.1| 3704|Caenorhabditis elegans laminin alpha
chain protein.
Length = 3704
Score = 34.7 bits (76), Expect = 0.73
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE---PPLFI 836
D + + T PK D V L + E T+ T EEPTEE AE PP+ +
Sbjct: 3240 DENISTTTTAAPKPTDDSDVAVLPIDEEEESTTTTTTTTTEEPTEEPAEMRDPPVTV 3296
>AB001074-1|BAA19229.1| 3704|Caenorhabditis elegans laminin alpha
protein.
Length = 3704
Score = 34.7 bits (76), Expect = 0.73
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE---PPLFI 836
D + + T PK D V L + E T+ T EEPTEE AE PP+ +
Sbjct: 3240 DENISTTTTAAPKPTDDSDVAVLPIDEEEESTTTTTTTTTEEPTEEPAEMRDPPVTV 3296
>Z81137-2|CAB03465.1| 386|Caenorhabditis elegans Hypothetical
protein W02D9.3 protein.
Length = 386
Score = 34.3 bits (75), Expect = 0.97
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 154 EKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPE-KINVP 212
E D+ S+E ++K VS P + + S P + A + +++NE E K+ V
Sbjct: 34 ESEDVTSSEEMQNKNPVSAPEKRAKTASFSPPPALSP-----AHSIQMENEEIEVKMEVD 88
Query: 213 DDKETSQTPTSFNKRSKLTPIKIERKEME 241
D+E + P KR+K+ K KE E
Sbjct: 89 SDEEEKKLPKITEKRAKMVYKKKPEKEKE 117
>Z70286-6|CAA94293.1| 3672|Caenorhabditis elegans Hypothetical protein
K08C7.3b protein.
Length = 3672
Score = 34.3 bits (75), Expect = 0.97
Identities = 18/49 (36%), Positives = 22/49 (44%)
Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
D + + T PK D V L + E T+ T EEPTEE AE
Sbjct: 3240 DENISTTTTAAPKPTDDSDVAVLPIDEEEESTTTTTTTTTEEPTEEPAE 3288
>AL033509-1|CAA22059.1| 1494|Caenorhabditis elegans Hypothetical
protein Y113G7C.1 protein.
Length = 1494
Score = 34.3 bits (75), Expect = 0.97
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 5/96 (5%)
Query: 308 KQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQT 367
+Q+ I ++ +E K K Q F + D+E+ E ++ ++ +KKDE ++K+
Sbjct: 1009 RQHKIHEKDREEEKKRKTQDFQDQQDADIERAEADEQRRKM-NVERAKKDEERAKKDKRD 1067
Query: 368 LEELPKED----VPEQYTITPRKSSAQKIDEIVDEV 399
EE K+D ++ K +KID++ EV
Sbjct: 1068 AEERRKKDEERAKKDKEDAKKAKEDQEKIDKLAAEV 1103
>Z68107-1|CAA92132.1| 264|Caenorhabditis elegans Hypothetical
protein F48C5.1 protein.
Length = 264
Score = 33.9 bits (74), Expect = 1.3
Identities = 17/62 (27%), Positives = 27/62 (43%)
Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
V QG SV++ + ++ W + P+K+ K+ D + I KD GVY
Sbjct: 46 VEQGSSVLIRCEHPNGKVASLRWLRGGSPIKSEYVKTKKDASFVEITNYLPDKDNGVYEC 105
Query: 806 KA 807
A
Sbjct: 106 SA 107
>Z46267-4|CAD45594.1| 517|Caenorhabditis elegans Hypothetical
protein F49E2.2b protein.
Length = 517
Score = 33.9 bits (74), Expect = 1.3
Identities = 14/64 (21%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 411 FYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVP 470
F+ P + G + + A + E + + G+++ +L ++ W +V+ ++ GWVP
Sbjct: 454 FFNPSQY--GSILIVNDDFNASSGEQMTVNRGDKVILLKCGSRGWVFVRDSISNRTGWVP 511
Query: 471 AQYL 474
Y+
Sbjct: 512 EPYV 515
>Z46267-3|CAA86421.3| 522|Caenorhabditis elegans Hypothetical
protein F49E2.2a protein.
Length = 522
Score = 33.9 bits (74), Expect = 1.3
Identities = 14/64 (21%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 411 FYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVP 470
F+ P + G + + A + E + + G+++ +L ++ W +V+ ++ GWVP
Sbjct: 459 FFNPSQY--GSILIVNDDFNASSGEQMTVNRGDKVILLKCGSRGWVFVRDSISNRTGWVP 516
Query: 471 AQYL 474
Y+
Sbjct: 517 EPYV 520
>U41270-3|ABC71846.1| 254|Caenorhabditis elegans Hypothetical
protein AH9.3 protein.
Length = 254
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/94 (22%), Positives = 41/94 (43%)
Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219
DS + +V P +++ E EE+ T+ D EVPEK + ++ E +Q
Sbjct: 14 DSSLPDESMEVDGPEDLSVKKEVQEAVKTEEAGSSPKATTTTDGEVPEKDSADENAEKNQ 73
Query: 220 TPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDG 253
+ N +++ + + K ++A+ DG
Sbjct: 74 VDSMENPKTEEGIVTADEKVDSSDDNKNAQKTDG 107
>U41034-9|AAA82383.1| 197|Caenorhabditis elegans Hypothetical
protein M02D8.1 protein.
Length = 197
Score = 33.9 bits (74), Expect = 1.3
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAI-- 684
+ G P F KP D G+ I+++ R + E W FK E+ V + + +
Sbjct: 94 VAAGNAPDFHDKPHIVQRDNGNVIVIKVRAKSHLEMKAEW-FKDEKPVKFTDRVKAVVKK 152
Query: 685 -ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
+ D + +L+IT +K E Y V N EG+
Sbjct: 153 DDKDKDGFQFLLEITGPQKDDEAKYKCVVKNSEGQ 187
>U40797-14|AAB37544.2| 200|Caenorhabditis elegans Hypothetical
protein C28C12.1 protein.
Length = 200
Score = 33.9 bits (74), Expect = 1.3
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 7/84 (8%)
Query: 323 VKKQVFVPPKL-PDVEKTELEQPLFSYEDIVESKKDENEIIQEKQT-----LEELPKEDV 376
+KK+ +L P+ QP S D+ +KK E ++I+EK+ EE P +D
Sbjct: 23 IKKKTSSKSRLSPNGTPKPASQPALSPLDLTPAKKVEEKVIEEKKVENNPKKEEEPVKDG 82
Query: 377 PEQYTITPRKSSAQKIDEIVDEVT 400
E P+KSS +K D ++ E T
Sbjct: 83 KEVVQDQPKKSSREK-DMMLKEKT 105
>AF067608-1|AAC17654.2| 544|Caenorhabditis elegans Hypothetical
protein B0511.6 protein.
Length = 544
Score = 33.9 bits (74), Expect = 1.3
Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Query: 335 DVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDE 394
DV+K L++ L +D E KK + +++E +EE +E+V E+ +SS K+ E
Sbjct: 4 DVKKKVLKRKLKQMKDGHEKKKAKEVVVEEP--MEEEDEEEVEEEQKHQTEESSETKVSE 61
Query: 395 IVDEVT 400
+ + T
Sbjct: 62 FLTKTT 67
>AF039047-14|AAM15588.1| 1040|Caenorhabditis elegans Human mlk
(mixed lineage kinase)homolog protein 1, isoform a
protein.
Length = 1040
Score = 33.9 bits (74), Expect = 1.3
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 6/121 (4%)
Query: 387 SSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLY 446
++A + V EV I+ + P+ R A Y Y A+ D+ +NL G +
Sbjct: 40 TTASTSTDSVPEVRIRSESSQVSRESPPI--RASKAFVASYEYEAQKDDELNLPLGAIIT 97
Query: 447 ILDT-SNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEE 505
++ +N+D WY + L + G P+ Y E Y L + ++I LPV + S+
Sbjct: 98 LVTVETNEDGWY-RGELNGKVGLFPSNYAR-EVTYKDNLVEFKQDEI-MLPVAVRTLSDC 154
Query: 506 Q 506
Q
Sbjct: 155 Q 155
>AF039047-13|AAM15589.1| 978|Caenorhabditis elegans Human mlk
(mixed lineage kinase)homolog protein 1, isoform b
protein.
Length = 978
Score = 33.9 bits (74), Expect = 1.3
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 6/121 (4%)
Query: 387 SSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLY 446
++A + V EV I+ + P+ R A Y Y A+ D+ +NL G +
Sbjct: 40 TTASTSTDSVPEVRIRSESSQVSRESPPI--RASKAFVASYEYEAQKDDELNLPLGAIIT 97
Query: 447 ILDT-SNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEE 505
++ +N+D WY + L + G P+ Y E Y L + ++I LPV + S+
Sbjct: 98 LVTVETNEDGWY-RGELNGKVGLFPSNYAR-EVTYKDNLVEFKQDEI-MLPVAVRTLSDC 154
Query: 506 Q 506
Q
Sbjct: 155 Q 155
>Z81525-1|CAB04256.1| 897|Caenorhabditis elegans Hypothetical
protein F33A8.1 protein.
Length = 897
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 160 DSQEDESKPDVSQP--PQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKET 217
+ +E+E K QP P+ E++ S + ES + +T +N+ EKI DD +
Sbjct: 17 EEREEEEKESSEQPDTPKTSSEKSASRSQSPRESREVSQETETSENQ--EKIKEKDDGDD 74
Query: 218 SQ-TPTSFNKRSKLTPIKIERKEMEVSTPQ 246
TP S+ R K ++ E +P+
Sbjct: 75 QPGTPNSYRSRETSPAPKRSKETRESESPE 104
>Z81114-2|CAB03286.1| 604|Caenorhabditis elegans Hypothetical
protein T04D3.2 protein.
Length = 604
Score = 33.5 bits (73), Expect = 1.7
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Query: 323 VKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPK-EDVPEQYT 381
++ V V + +E+ ++ Y+ + +KK EI +K+ LEE K E + E T
Sbjct: 436 IQTPVTVKTFIVQMEEERRKKTKIIYDKVQLAKKKNKEIKLKKKVLEEEEKTEKMMENMT 495
Query: 382 ITPRKSSAQKIDEIVD-EVTIKKRLNPFE-IFYTPVEVRCGDTVF 424
+ + ++K + VD E+ ++ NPF+ I + R D +F
Sbjct: 496 LENSEDQSKKDEATVDAEIRTEESDNPFKRIPVIDAQKRLIDAIF 540
>U41992-7|AAA83358.1| 374|Caenorhabditis elegans Hypothetical
protein F32E10.6 protein.
Length = 374
Score = 33.5 bits (73), Expect = 1.7
Identities = 29/107 (27%), Positives = 56/107 (52%), Gaps = 7/107 (6%)
Query: 155 KSDLFDSQEDESKPDVSQP-PQNIIEEAKSEPKLIEESEQPIA-KTSEIDN--EVPEKIN 210
KS DS ++E + +V + P+ + K +E E+P+A K S+ E PE+ +
Sbjct: 194 KSKDDDSSDEEEEEEVKEKSPKKSSKSTKRAASDDDEEEEPVATKKSKKSKRAETPEEED 253
Query: 211 VPDDKETSQTP--TSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQ 255
+++E +TP T +KR++ + E +E V TP+ +++ P+
Sbjct: 254 -DEEEEVVKTPKKTKKSKRAETPEEEDEVEEEVVKTPKKSKSSKSPK 299
>U19615-1|AAB51351.1| 897|Caenorhabditis elegans Nucampholin
protein.
Length = 897
Score = 33.5 bits (73), Expect = 1.7
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 160 DSQEDESKPDVSQP--PQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKET 217
+ +E+E K QP P+ E++ S + ES + +T +N+ EKI DD +
Sbjct: 17 EEREEEEKESSEQPDTPKTSSEKSASRSQSPRESREVSQETETSENQ--EKIKEKDDGDD 74
Query: 218 SQ-TPTSFNKRSKLTPIKIERKEMEVSTPQ 246
TP S+ R K ++ E +P+
Sbjct: 75 QPGTPNSYRSRETSPAPKRSKETRESESPE 104
>Z72503-6|CAA96594.4| 273|Caenorhabditis elegans Hypothetical
protein C26C6.8 protein.
Length = 273
Score = 33.1 bits (72), Expect = 2.2
Identities = 14/64 (21%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 428 SYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKK 487
S+ + I++ +GE + +L+ S+ +W Y+ ++ + G+VP+ ++ + Q +
Sbjct: 145 SFDGSAPDDISVKDGESVTVLNISDPEWTYI-RNSDNQSGFVPSSHVKIPHEILQQASRV 203
Query: 488 LNEK 491
+ EK
Sbjct: 204 IKEK 207
>X56213-1|CAA39670.1| 1651|Caenorhabditis elegans vitellogenin
protein.
Length = 1651
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 314 SRNIKEAAKVKKQVFV--PPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEEL 371
S NIK A QV + K EK++ ++P FS+ ++ + + E E++ T+EE+
Sbjct: 145 SENIKRAVINMLQVNILKKEKYEGAEKSDNQEPTFSFTNVERTLEGECEVL---YTVEEI 201
Query: 372 PKED 375
KED
Sbjct: 202 KKED 205
>U43282-1|AAA83613.2| 547|Caenorhabditis elegans Hypothetical protein
T22E5.3 protein.
Length = 547
Score = 33.1 bits (72), Expect = 2.2
Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
PS+ R + E T SV++KW EP + + +Y I G S T+ V + E+
Sbjct: 135 PSEARELTIDEKTENSVSIKWKEP-TESPDLVDHYTIHLIERTGVSETESVFTTEDI-EY 192
Query: 1926 CIENI 1930
+E +
Sbjct: 193 TLEGL 197
>M11499-1|AAA28165.1| 259|Caenorhabditis elegans protein (
C.elegans vitellogenin6 gene ancoding yolk protein
VIT180. ).
Length = 259
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 314 SRNIKEAAKVKKQVFV--PPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEEL 371
S NIK A QV + K EK++ ++P FS+ ++ + + E E++ T+EE+
Sbjct: 145 SENIKRAVINMLQVNILKKEKYEGAEKSDNQEPTFSFTNVERTLEGECEVL---YTVEEI 201
Query: 372 PKED 375
KED
Sbjct: 202 KKED 205
>AF047659-3|AAC04423.2| 1650|Caenorhabditis elegans Vitellogenin
structural genes (yolk protein genes) protein 6, isoform
a protein.
Length = 1650
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 314 SRNIKEAAKVKKQVFV--PPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEEL 371
S NIK A QV + K EK++ ++P FS+ ++ + + E E++ T+EE+
Sbjct: 145 SENIKRAVINMLQVNILKKEKYEGAEKSDNQEPTFSFTNVERTLEGECEVL---YTVEEI 201
Query: 372 PKED 375
KED
Sbjct: 202 KKED 205
>AF047659-2|AAQ91901.1| 1651|Caenorhabditis elegans Vitellogenin
structural genes (yolk protein genes) protein 6, isoform
c protein.
Length = 1651
Score = 33.1 bits (72), Expect = 2.2
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 314 SRNIKEAAKVKKQVFV--PPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEEL 371
S NIK A QV + K EK++ ++P FS+ ++ + + E E++ T+EE+
Sbjct: 145 SENIKRAVINMLQVNILKKEKYEGAEKSDNQEPTFSFTNVERTLEGECEVL---YTVEEI 201
Query: 372 PKED 375
KED
Sbjct: 202 KKED 205
>AC006742-1|AAF60499.2| 1393|Caenorhabditis elegans Hypothetical
protein Y38C1AB.4 protein.
Length = 1393
Score = 33.1 bits (72), Expect = 2.2
Identities = 33/164 (20%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Query: 660 IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
I EP + F EE+ E+I E + + + V+ + + +V+ + ++
Sbjct: 370 IEEPVVVDRFVEEEVDEKEDIDAIFEKYRKVRKDIFEKNGVENLKNLNFFRTSVSADPKS 429
Query: 720 SLPIVL--KIKTGEKE-PPQVIEPLKSMIVRQGESVILSAQVVG--NPRPTITWCKN--- 771
PI++ + K +K+ P V+ +S I+++ S++ S ++ G + R ++T ++
Sbjct: 430 HTPILMADEYKEPQKQVPAPVVVAQESPILKRRNSLVPS-RISGRQSTRRSVTSVRSMRG 488
Query: 772 NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
+ +A+P D H L+ K + + + E++E + E
Sbjct: 489 KRKTRAIPEFFDLTRHQNIRLRAPATKKKRISLHRVEDTEAVVE 532
>Z81086-3|CAD56586.1| 711|Caenorhabditis elegans Hypothetical protein
F53B6.2b protein.
Length = 711
Score = 32.7 bits (71), Expect = 3.0
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 3/42 (7%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
+ W K+G +I+ HI+++ +G L+++ ++DAG Y C
Sbjct: 350 IYWKKNGKKIKNDAHIKVSANG---NLRVFHARMEDAGVYEC 388
>Z81086-2|CAB03121.3| 1045|Caenorhabditis elegans Hypothetical protein
F53B6.2a protein.
Length = 1045
Score = 32.7 bits (71), Expect = 3.0
Identities = 13/42 (30%), Positives = 26/42 (61%), Gaps = 3/42 (7%)
Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
+ W K+G +I+ HI+++ +G L+++ ++DAG Y C
Sbjct: 684 IYWKKNGKKIKNDAHIKVSANG---NLRVFHARMEDAGVYEC 722
>Z66495-4|CAA91271.1| 954|Caenorhabditis elegans Hypothetical
protein C36A4.5 protein.
Length = 954
Score = 32.7 bits (71), Expect = 3.0
Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
Query: 330 PPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELP------KEDVPEQYTIT 383
PP+L + T ++P+ ED+ ++ ++ +++ +E+P K+ P TI
Sbjct: 497 PPRLEEARATHPKEPIVDAEDLAKAPQEVDDVANLADVEDEIPPPVGAFKKPEPRPETIV 556
Query: 384 PRKSSAQKIDEIVDEVTIKKRLNPFEI 410
S +I E VD K+ +P E+
Sbjct: 557 AGGSGEDRIPEPVDAF---KKPDPVEL 580
>Z22179-12|CAA80165.1| 144|Caenorhabditis elegans Hypothetical
protein F58A4.9 protein.
Length = 144
Score = 32.7 bits (71), Expect = 3.0
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 182 KSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEME 241
K K++EE+E+ A+T E+D E P++ DD+E P S K L P E+
Sbjct: 3 KKNEKIVEEAEKVEAETMEVD-EQPQETPQVDDEEDLNVP-SKKKMEILDPKSFEQDPSN 60
Query: 242 VSTPQHAE 249
++ + E
Sbjct: 61 LTLIMYEE 68
>U70850-3|AAB09122.3| 596|Caenorhabditis elegans Zinc finger plus
homeodomain, axonguidance protein 1 protein.
Length = 596
Score = 32.7 bits (71), Expect = 3.0
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Query: 147 DLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKL--IEESEQPIAKTSEIDNE 204
+++ ++L +++LF S E+ + P +Q P A EPK+ ++E E +E+ E
Sbjct: 118 NMDYMSLLQANLFQSLENGTSPTPTQEPS---APASPEPKIEVVDEPEVSSEVKTEVKTE 174
Query: 205 VPEKINVPDDKETSQTPTSFN 225
V + +VP++ T S +
Sbjct: 175 VKTEDSVPEESITPAVSMSLS 195
>U64857-1|AAC25868.1| 2167|Caenorhabditis elegans Hypothetical protein
C37C3.6b protein.
Length = 2167
Score = 32.7 bits (71), Expect = 3.0
Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
G+T + C Y ITW++ +++ F ++N TL I + DAG +TC
Sbjct: 1999 GNTFRIRCN--SYGVLPITWYKNGGLLQ----FGSRITEENDDTLEIVDALTADAGVYTC 2052
Query: 584 VAKNAAGFASSTTELIVEAP 603
+A + + +I P
Sbjct: 2053 IAGQDSTMSEGVEVVIKRLP 2072
Score = 31.9 bits (69), Expect = 5.2
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 4/58 (6%)
Query: 1125 TFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
TF I L + W+K+G +QF + I + L+I D DAG Y+C G
Sbjct: 2001 TFRIRCNSYGVLPITWYKNGGLLQFGSRI---TEENDDTLEIVDALTADAGVYTCIAG 2055
>U39997-6|AAN60517.1| 942|Caenorhabditis elegans Clear protein 1,
isoform c protein.
Length = 942
Score = 32.7 bits (71), Expect = 3.0
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-----PSKPEGPVIMREISRE 1681
TS + IK+L+ + + YT+ S G E T K P K E ++ S
Sbjct: 328 TSPVSIKDLRAA--TPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSAL 385
Query: 1682 SVTIEWKPPLDDGGLELTKYAI 1703
S +EWK P + G +TKY +
Sbjct: 386 SCEVEWKSPAEPNG-RITKYFV 406
>U39997-5|AAN60515.1| 1409|Caenorhabditis elegans Clear protein 1,
isoform a protein.
Length = 1409
Score = 32.7 bits (71), Expect = 3.0
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-----PSKPEGPVIMREISRE 1681
TS + IK+L+ + + YT+ S G E T K P K E ++ S
Sbjct: 328 TSPVSIKDLRAA--TPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSAL 385
Query: 1682 SVTIEWKPPLDDGGLELTKYAI 1703
S +EWK P + G +TKY +
Sbjct: 386 SCEVEWKSPAEPNG-RITKYFV 406
>U39997-4|AAN60516.1| 1444|Caenorhabditis elegans Clear protein 1,
isoform b protein.
Length = 1444
Score = 32.7 bits (71), Expect = 3.0
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-----PSKPEGPVIMREISRE 1681
TS + IK+L+ + + YT+ S G E T K P K E ++ S
Sbjct: 363 TSPVSIKDLRAA--TPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSAL 420
Query: 1682 SVTIEWKPPLDDGGLELTKYAI 1703
S +EWK P + G +TKY +
Sbjct: 421 SCEVEWKSPAEPNG-RITKYFV 441
>AY289599-1|AAP43944.1| 596|Caenorhabditis elegans ZAG-1 protein.
Length = 596
Score = 32.7 bits (71), Expect = 3.0
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Query: 147 DLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKL--IEESEQPIAKTSEIDNE 204
+++ ++L +++LF S E+ + P +Q P A EPK+ ++E E +E+ E
Sbjct: 118 NMDYMSLLQANLFQSLENGTSPTPTQEPS---APASPEPKIEVVDEPEVSSEVKTEVKTE 174
Query: 205 VPEKINVPDDKETSQTPTSFN 225
V + +VP++ T S +
Sbjct: 175 VKTEDSVPEESITPAVSMSLS 195
>AY224511-1|AAP37457.1| 596|Caenorhabditis elegans ZAG-1 protein.
Length = 596
Score = 32.7 bits (71), Expect = 3.0
Identities = 21/81 (25%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Query: 147 DLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKL--IEESEQPIAKTSEIDNE 204
+++ ++L +++LF S E+ + P +Q P A EPK+ ++E E +E+ E
Sbjct: 118 NMDYMSLLQANLFQSLENGTSPTPTQEPS---APASPEPKIEVVDEPEVSSEVKTEVKTE 174
Query: 205 VPEKINVPDDKETSQTPTSFN 225
V + +VP++ T S +
Sbjct: 175 VKTEDSVPEESITPAVSMSLS 195
>AF047881-1|AAC27552.1| 942|Caenorhabditis elegans truncated CLR-1
protein.
Length = 942
Score = 32.7 bits (71), Expect = 3.0
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-----PSKPEGPVIMREISRE 1681
TS + IK+L+ + + YT+ S G E T K P K E ++ S
Sbjct: 328 TSPVSIKDLRAA--TPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSAL 385
Query: 1682 SVTIEWKPPLDDGGLELTKYAI 1703
S +EWK P + G +TKY +
Sbjct: 386 SCEVEWKSPAEPNG-RITKYFV 406
>AF047880-1|AAC27551.1| 1409|Caenorhabditis elegans CLR-1 protein.
Length = 1409
Score = 32.7 bits (71), Expect = 3.0
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-----PSKPEGPVIMREISRE 1681
TS + IK+L+ + + YT+ S G E T K P K E ++ S
Sbjct: 328 TSPVSIKDLRAA--TPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSAL 385
Query: 1682 SVTIEWKPPLDDGGLELTKYAI 1703
S +EWK P + G +TKY +
Sbjct: 386 SCEVEWKSPAEPNG-RITKYFV 406
>AF047661-6|AAC04438.2| 577|Caenorhabditis elegans Hypothetical
protein M70.5 protein.
Length = 577
Score = 32.7 bits (71), Expect = 3.0
Identities = 47/164 (28%), Positives = 71/164 (43%), Gaps = 24/164 (14%)
Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVE---MNVTILDKPSPPGKPNILEIDSSSINICW 1401
LT V+N + I K++L + A E +NV L+ SP + + + +S N
Sbjct: 37 LTAIDVQNVELAIEKIQLHLSRQTALTEEDILNVKNLNFFSPRPQESTETLPGTS-NSRI 95
Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
DEPE E +E+D E S+ + +++Q S + L F +N+V I
Sbjct: 96 DEPE------------ELEELDYNE--SLSDWSESQRSAEELAEEDELNFVENGLNDVKI 141
Query: 1462 SDASETTEYYKVI-KETKIQSPTVEKPL-----KNITTEPNEDI 1499
E T Y+ I ET + + K L K I TE EDI
Sbjct: 142 ESEIEETAYFPAIPPETAENAWEILKNLQILKEKAIKTEEEEDI 185
>AC006810-1|AAF59633.1| 182|Caenorhabditis elegans Hypothetical
protein Y5H2B.3 protein.
Length = 182
Score = 32.7 bits (71), Expect = 3.0
Identities = 26/118 (22%), Positives = 59/118 (50%), Gaps = 14/118 (11%)
Query: 312 ILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEEL 371
I + I + + KK+ K+ D K E ++ +D+++ +K E Q+K+ E++
Sbjct: 59 ISCKRILKKLERKKKALANQKVTDPAKKEHKEHEQEAKDLIKKEKSE----QKKEAKEQV 114
Query: 372 PKEDVPEQYTITPRKSSAQKI----------DEIVDEVTIKKRLNPFEIFYTPVEVRC 419
KE E+ + ++ S++K+ ++ ++V IKK++ P + +T + +C
Sbjct: 115 NKEKSEEKKKESVKRKSSEKLEAPSKKAKNSEDQENQVAIKKKVTPPKTKHTALFKKC 172
>Z68116-7|CAA92170.1| 238|Caenorhabditis elegans Hypothetical protein
F42F12.2 protein.
Length = 238
Score = 32.3 bits (70), Expect = 3.9
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
FI DF ++ + A+ + SETA + W + +++ +Y G L IR
Sbjct: 150 FISMTVDFRLEISNNAVA-LSCRSETATEWSWHKGEQLLTNDGERYQMFPSGD---LIIR 205
Query: 1078 NTSVHDEGEYSCILRD 1093
N S D GEY+C R+
Sbjct: 206 NISWSDMGEYNCTARN 221
>Z29117-5|CAC42271.1| 1704|Caenorhabditis elegans Hypothetical protein
C48B4.4c protein.
Length = 1704
Score = 32.3 bits (70), Expect = 3.9
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 804 TLKAENSEGIAETSAVITVEEPTE-----ENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
TLK+ N++ + S + EP++ EN P F++I +++ G +++ T+
Sbjct: 982 TLKSNNTDQFSVRSLTPSGIEPSKVVWRFENGTIPEEAANFEKI-LRKSGGFEVLNYNTK 1040
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIE 889
NP+P+IT E+ P TI + +N+E
Sbjct: 1041 NPLPNITKSLIGEM--PPATIGMTMNSDNLE 1069
>Z29117-4|CAA82384.2| 1691|Caenorhabditis elegans Hypothetical protein
C48B4.4b protein.
Length = 1691
Score = 32.3 bits (70), Expect = 3.9
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 804 TLKAENSEGIAETSAVITVEEPTE-----ENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
TLK+ N++ + S + EP++ EN P F++I +++ G +++ T+
Sbjct: 969 TLKSNNTDQFSVRSLTPSGIEPSKVVWRFENGTIPEEAANFEKI-LRKSGGFEVLNYNTK 1027
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIE 889
NP+P+IT E+ P TI + +N+E
Sbjct: 1028 NPLPNITKSLIGEM--PPATIGMTMNSDNLE 1056
>AL117204-30|CAB55138.1| 1097|Caenorhabditis elegans Hypothetical
protein Y116A8C.36 protein.
Length = 1097
Score = 32.3 bits (70), Expect = 3.9
Identities = 14/54 (25%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
Query: 425 AVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEK-GWVPAQYLMDE 477
AVY Y A + + G+ + + D S +WW + K G P+ Y+ +
Sbjct: 1044 AVYDYEASQPDELGFKTGDVIIVTDKSEAEWWSGHREQDPSKSGLFPSNYVQQQ 1097
>AF456249-1|AAL59607.1| 238|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-2 protein.
Length = 238
Score = 32.3 bits (70), Expect = 3.9
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
FI DF ++ + A+ + SETA + W + +++ +Y G L IR
Sbjct: 150 FISMTVDFRLEISNNAVA-LSCRSETATEWSWHKGEQLLTNDGERYQMFPSGD---LIIR 205
Query: 1078 NTSVHDEGEYSCILRD 1093
N S D GEY+C R+
Sbjct: 206 NISWSDMGEYNCTARN 221
>AF357877-1|AAK27715.1| 835|Caenorhabditis elegans
receptor-mediated endocytosis 1isoform II protein.
Length = 835
Score = 32.3 bits (70), Expect = 3.9
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEI--DNEVP 206
E + E DL + E E D+ + ++EE K ++ ESE P EI + E+
Sbjct: 125 EELNAETEDLSERSEVEKDEDLGR----VVEEHKEPAQVPVESETPETSKKEIHQEEEIS 180
Query: 207 EKINVPDDKETSQTPTSFNKRSKLTPIKIE-RKEMEVSTPQHAET 250
E VP+ E + N ++T +K E +E+++S + ET
Sbjct: 181 ELEKVPETVE--EEIEVVNTSVEITEVKKEVIEEVKISGLKEEET 223
>AF078790-14|AAC26930.1| 335|Caenorhabditis elegans Hypothetical
protein F36H12.3 protein.
Length = 335
Score = 32.3 bits (70), Expect = 3.9
Identities = 19/68 (27%), Positives = 31/68 (45%)
Query: 154 EKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPD 213
+KSD D ++DE K + + EE K E K ++ E+ K E E ++ D
Sbjct: 153 KKSDNKDDKDDEKKEEKKDDKEEKKEEKKEEKKEEKKEEKKEEKKEEEKKEEKKEEKKED 212
Query: 214 DKETSQTP 221
+K+ P
Sbjct: 213 EKKVEPKP 220
>AF049142-1|AAC24116.1| 1704|Caenorhabditis elegans ATP-binding
cassette transporter protein.
Length = 1704
Score = 32.3 bits (70), Expect = 3.9
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 804 TLKAENSEGIAETSAVITVEEPTE-----ENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
TLK+ N++ + S + EP++ EN P F++I +++ G +++ T+
Sbjct: 982 TLKSNNTDQFSVRSLTPSGIEPSKVVWRFENGTIPEEAANFEKI-LRKSGGFEVLNYNTK 1040
Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIE 889
NP+P+IT E+ P TI + +N+E
Sbjct: 1041 NPLPNITKSLIGEM--PPATIGMTMNSDNLE 1069
>AC006835-1|AAF40015.2| 903|Caenorhabditis elegans Hypothetical
protein ZK993.2 protein.
Length = 903
Score = 32.3 bits (70), Expect = 3.9
Identities = 16/52 (30%), Positives = 27/52 (51%)
Query: 196 AKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQH 247
A EID E+ +K+ +D++ +TP + SK + +KE+E QH
Sbjct: 319 ADALEIDREIEDKMRKLEDEQKKKTPMEVEEDSKFFKFRALQKEIERVHIQH 370
>AC006695-8|AAF39978.1| 786|Caenorhabditis elegans Receptor
mediated endocytosis protein1, isoform a protein.
Length = 786
Score = 32.3 bits (70), Expect = 3.9
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEI--DNEVP 206
E + E DL + E E D+ + ++EE K ++ ESE P EI + E+
Sbjct: 76 EELNAETEDLSERSEVEKDEDLGR----VVEEHKEPAQVPVESETPETSKKEIHQEEEIS 131
Query: 207 EKINVPDDKETSQTPTSFNKRSKLTPIKIE-RKEMEVSTPQHAET 250
E VP+ E + N ++T +K E +E+++S + ET
Sbjct: 132 ELEKVPETVE--EEIEVVNTSVEITEVKKEVIEEVKISGLKEEET 174
>AC006695-6|AAF39979.1| 835|Caenorhabditis elegans Receptor
mediated endocytosis protein1, isoform b protein.
Length = 835
Score = 32.3 bits (70), Expect = 3.9
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEI--DNEVP 206
E + E DL + E E D+ + ++EE K ++ ESE P EI + E+
Sbjct: 125 EELNAETEDLSERSEVEKDEDLGR----VVEEHKEPAQVPVESETPETSKKEIHQEEEIS 180
Query: 207 EKINVPDDKETSQTPTSFNKRSKLTPIKIE-RKEMEVSTPQHAET 250
E VP+ E + N ++T +K E +E+++S + ET
Sbjct: 181 ELEKVPETVE--EEIEVVNTSVEITEVKKEVIEEVKISGLKEEET 223
>Z95559-8|CAB54437.1| 720|Caenorhabditis elegans Hypothetical
protein Y41E3.16 protein.
Length = 720
Score = 31.9 bits (69), Expect = 5.2
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 14/77 (18%)
Query: 163 EDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPT 222
EDE +P+ + P EP I+E E+ K S I EVP+ +E + P
Sbjct: 236 EDEDEPEAAADP---------EPPKIQEPEKKKQKVS-IKEEVPDVAAAVVSQEPQEPP- 284
Query: 223 SFNKRSKLTPIKIERKE 239
K+ KLT IK+E +E
Sbjct: 285 ---KKQKLTRIKVEVEE 298
>Z81053-1|CAB02877.1| 385|Caenorhabditis elegans Hypothetical
protein E02A10.2 protein.
Length = 385
Score = 31.9 bits (69), Expect = 5.2
Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Query: 312 ILSRNIKEAAKVKKQ--VFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLE 369
IL N KE A+ ++ PK + +K E+E+ + E KK+E + +E++ E
Sbjct: 272 ILRINHKEVAEKNEEDKKEEEPKKEEEKKEEVEKKEEDEKKDEEPKKEEEK--KEEEQKE 329
Query: 370 ELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFE 409
E+ K++ E+ P+K +K +E E ++++ E
Sbjct: 330 EVEKKEEEEKKDEEPKKEEEKKEEEEKKEDEVEEKSEKVE 369
Database: celegans
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 12,573,161
Number of sequences in database: 27,539
Lambda K H
0.312 0.131 0.377
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 53,462,553
Number of Sequences: 27539
Number of extensions: 2429007
Number of successful extensions: 19174
Number of sequences better than 10.0: 281
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 115
Number of HSP's that attempted gapping in prelim test: 5928
Number of HSP's gapped (non-prelim): 6407
length of query: 2130
length of database: 12,573,161
effective HSP length: 93
effective length of query: 2037
effective length of database: 10,012,034
effective search space: 20394513258
effective search space used: 20394513258
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 67 (31.1 bits)
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