Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000623-TA|BGIBMGA000623-PA|IPR013098|Immunoglobulin
I-set, IPR000577|Carbohydrate kinase, FGGY,
IPR007110|Immunoglobulin-like, IPR003599|Immunoglobulin subtype,
IPR003598|Immunoglobulin subtype 2
(1910 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 129 8e-29
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 114 3e-24
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 114 3e-24
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 114 3e-24
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 114 3e-24
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 104 4e-21
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 104 4e-21
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 104 4e-21
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 104 4e-21
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 103 5e-21
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 103 6e-21
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 103 6e-21
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 103 6e-21
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 103 6e-21
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 103 6e-21
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 103 8e-21
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 102 1e-20
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 98 3e-19
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 98 3e-19
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 98 3e-19
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 98 3e-19
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 98 3e-19
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 97 7e-19
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 97 7e-19
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 97 7e-19
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 97 7e-19
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 96 9e-19
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 95 2e-18
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 92 2e-17
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 89 1e-16
AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific tit... 83 9e-15
AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein. 83 9e-15
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 79 2e-13
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 78 4e-13
BC111395-1|AAI11396.1| 554|Homo sapiens NEXN protein protein. 77 6e-13
AF114264-1|AAD29607.1| 448|Homo sapiens unknown protein. 77 6e-13
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 76 1e-12
DQ464902-1|ABE97925.1| 675|Homo sapiens nexilin protein. 75 3e-12
BC114445-1|AAI14446.1| 567|Homo sapiens NEXN protein protein. 75 3e-12
BC114444-1|AAI14445.1| 567|Homo sapiens NEXN protein protein. 75 3e-12
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 75 3e-12
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 75 3e-12
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 75 3e-12
BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein pr... 74 4e-12
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 74 4e-12
AK057954-1|BAB71622.1| 505|Homo sapiens protein ( Homo sapiens ... 74 4e-12
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 74 4e-12
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 74 6e-12
AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens ... 73 1e-11
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 73 1e-11
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 73 1e-11
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 73 1e-11
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 72 2e-11
BC008648-1|AAH08648.1| 358|Homo sapiens Unknown (protein for IM... 68 4e-10
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 67 5e-10
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 67 7e-10
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 67 7e-10
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 67 7e-10
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 66 9e-10
X15306-1|CAA33366.1| 1020|Homo sapiens heavy neurofilament subun... 66 1e-09
BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein. 66 1e-09
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein. 65 2e-09
BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein ... 65 2e-09
AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein. 65 3e-09
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 64 4e-09
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 64 5e-09
BC073969-1|AAH73969.1| 1026|Homo sapiens NEFH protein protein. 64 5e-09
AF203032-1|AAF13722.1| 1026|Homo sapiens neurofilament protein p... 64 5e-09
AB020652-1|BAA74868.2| 1034|Homo sapiens KIAA0845 protein protein. 64 5e-09
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 64 6e-09
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 64 6e-09
BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein pr... 64 6e-09
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 64 6e-09
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 63 8e-09
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 63 8e-09
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 63 8e-09
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 63 8e-09
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 63 1e-08
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 62 1e-08
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 62 1e-08
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 62 1e-08
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 62 2e-08
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 62 2e-08
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 62 2e-08
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 61 3e-08
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 61 3e-08
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 61 3e-08
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 61 3e-08
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 61 3e-08
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 61 4e-08
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 61 4e-08
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 61 4e-08
AJ489257-1|CAD33526.2| 461|Homo sapiens triadin protein. 60 6e-08
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 60 8e-08
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 60 8e-08
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 60 8e-08
AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens ... 60 8e-08
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 60 8e-08
Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C ... 60 1e-07
X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding pr... 60 1e-07
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 60 1e-07
U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding pr... 60 1e-07
AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein ... 60 1e-07
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 60 1e-07
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 60 1e-07
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 60 1e-07
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 60 1e-07
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 59 2e-07
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 59 2e-07
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 59 2e-07
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 59 2e-07
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 59 2e-07
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 59 2e-07
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 58 3e-07
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 58 3e-07
BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth facto... 58 3e-07
AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein. 58 3e-07
AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens ... 58 3e-07
AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein. 58 3e-07
AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor r... 58 3e-07
AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth facto... 58 3e-07
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 58 3e-07
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 58 3e-07
X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein. 58 4e-07
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 58 4e-07
U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H ... 57 7e-07
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 57 7e-07
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 57 7e-07
BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein ... 57 7e-07
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 57 7e-07
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 57 7e-07
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 56 9e-07
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 56 9e-07
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 56 9e-07
BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein. 56 9e-07
BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein. 56 9e-07
BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein. 56 9e-07
BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kin... 56 9e-07
BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kin... 56 9e-07
BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kin... 56 9e-07
BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kin... 56 9e-07
BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein. 56 9e-07
BC014671-1|AAH14671.1| 331|Homo sapiens MYOM3 protein protein. 56 9e-07
AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member... 56 9e-07
AL591178-2|CAH72089.1| 330|Homo sapiens myomesin family, member... 56 9e-07
AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens ... 56 9e-07
AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein ... 56 9e-07
AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein ... 56 9e-07
AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein ... 56 9e-07
AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein ... 56 9e-07
AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle... 56 9e-07
AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens ... 56 1e-06
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 56 1e-06
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 56 2e-06
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 56 2e-06
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 56 2e-06
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 56 2e-06
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 55 2e-06
BC132902-1|AAI32903.1| 354|Homo sapiens myosin binding protein ... 55 2e-06
BC132900-1|AAI32901.1| 354|Homo sapiens myosin binding protein ... 55 2e-06
AY211921-1|AAO65174.1| 294|Homo sapiens sarcoma antigen NY-SAR-... 55 2e-06
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 55 3e-06
BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein pr... 55 3e-06
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 55 3e-06
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 55 3e-06
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 55 3e-06
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 55 3e-06
AK093280-1|BAC04119.1| 330|Homo sapiens protein ( Homo sapiens ... 55 3e-06
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 54 4e-06
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 54 4e-06
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 54 4e-06
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 54 5e-06
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 54 5e-06
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 54 7e-06
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 54 7e-06
AL603911-1|CAI14448.1| 721|Homo sapiens triadin protein. 54 7e-06
AL603902-1|CAH70824.1| 721|Homo sapiens triadin protein. 54 7e-06
AL445259-1|CAI41045.1| 721|Homo sapiens triadin protein. 54 7e-06
AL357352-1|CAI16757.1| 721|Homo sapiens triadin protein. 54 7e-06
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 54 7e-06
AL133257-1|CAI19636.1| 721|Homo sapiens triadin protein. 54 7e-06
AC115538-1|AAY40987.1| 103|Homo sapiens unknown protein. 54 7e-06
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 54 7e-06
AL390252-10|CAI13179.1| 354|Homo sapiens myosin binding protein... 53 9e-06
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 53 9e-06
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 53 9e-06
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 53 1e-05
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 53 1e-05
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 53 1e-05
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 53 1e-05
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 53 1e-05
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 53 1e-05
U18985-1|AAA75315.1| 729|Homo sapiens triadin protein. 52 2e-05
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 52 2e-05
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 52 2e-05
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 52 2e-05
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 52 2e-05
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 52 2e-05
BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,... 52 2e-05
X69089-1|CAA48832.1| 1465|Homo sapiens 165kD protein protein. 52 3e-05
U57099-1|AAC50599.1| 113|Homo sapiens APEG-1 protein protein. 52 3e-05
L06237-1|AAA18904.1| 2468|Homo sapiens microtubule-associated pr... 52 3e-05
CR542201-1|CAG46998.1| 113|Homo sapiens APEG1 protein. 52 3e-05
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 52 3e-05
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 52 3e-05
BC006346-1|AAH06346.1| 113|Homo sapiens SPEG protein protein. 52 3e-05
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 52 3e-05
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 52 3e-05
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 52 3e-05
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 52 3e-05
AK128689-1|BAC87572.1| 175|Homo sapiens protein ( Homo sapiens ... 52 3e-05
AK126500-1|BAC86568.1| 170|Homo sapiens protein ( Homo sapiens ... 52 3e-05
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 52 3e-05
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 52 3e-05
AC053503-3|AAY15052.1| 113|Homo sapiens unknown protein. 52 3e-05
AL133563-1|CAB63717.1| 1132|Homo sapiens hypothetical protein pr... 51 4e-05
AB018284-1|BAA34461.2| 1222|Homo sapiens KIAA0741 protein protein. 51 4e-05
X69090-1|CAA48833.1| 1451|Homo sapiens 190kD protein protein. 51 5e-05
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 51 5e-05
AL050093-1|CAB43265.1| 145|Homo sapiens hypothetical protein pr... 51 5e-05
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 50 6e-05
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 50 6e-05
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 50 6e-05
BC014276-1|AAH14276.2| 417|Homo sapiens LRIG1 protein protein. 50 6e-05
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 50 6e-05
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 50 8e-05
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 50 8e-05
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 50 8e-05
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 50 8e-05
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 50 8e-05
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 50 8e-05
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 50 8e-05
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 50 1e-04
X64698-1|CAA45939.1| 1100|Homo sapiens titin protein. 50 1e-04
M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor pr... 50 1e-04
BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine kinas... 50 1e-04
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 50 1e-04
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 50 1e-04
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 50 1e-04
AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine kinas... 50 1e-04
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 50 1e-04
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 50 1e-04
AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine kinas... 50 1e-04
AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine kinas... 50 1e-04
AK125555-1|BAC86200.1| 373|Homo sapiens protein ( Homo sapiens ... 50 1e-04
AK092996-1|BAC04014.1| 787|Homo sapiens protein ( Homo sapiens ... 50 1e-04
AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein. 50 1e-04
AF279762-1|AAG33132.1| 541|Homo sapiens ROR2 protein. 50 1e-04
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 50 1e-04
AB209903-1|BAD93140.1| 1259|Homo sapiens LL5 beta protein varian... 50 1e-04
AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase... 50 1e-04
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 50 1e-04
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 49 1e-04
BC032639-1|AAH32639.1| 1220|Homo sapiens eukaryotic translation ... 49 1e-04
BC024300-1|AAH24300.1| 605|Homo sapiens FSTL4 protein protein. 49 1e-04
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 49 1e-04
AJ496194-1|CAD42711.1| 1253|Homo sapiens LL5 beta protein protein. 49 1e-04
AJ006776-1|CAB44357.1| 1220|Homo sapiens IF2 protein protein. 49 1e-04
AB028984-1|BAA83013.1| 693|Homo sapiens KIAA1061 protein protein. 49 1e-04
BC036502-1|AAH36502.1| 847|Homo sapiens follistatin-like 5 prot... 49 2e-04
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 49 2e-04
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 49 2e-04
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 49 2e-04
AL137695-1|CAB70877.1| 773|Homo sapiens hypothetical protein pr... 49 2e-04
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 49 2e-04
AC079227-1|AAY40948.1| 274|Homo sapiens unknown protein. 49 2e-04
AB033089-1|BAA86577.1| 850|Homo sapiens KIAA1263 protein protein. 49 2e-04
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 48 2e-04
BC116183-1|AAI16184.1| 1589|Homo sapiens myomesin 1, 185kDa prot... 48 2e-04
AL391994-7|CAI13752.1| 1071|Homo sapiens AT rich interactive dom... 48 2e-04
AL391994-6|CAI13751.1| 1226|Homo sapiens AT rich interactive dom... 48 2e-04
AL133418-7|CAI22963.1| 1071|Homo sapiens AT rich interactive dom... 48 2e-04
AL133418-6|CAI22962.1| 1226|Homo sapiens AT rich interactive dom... 48 2e-04
AJ621424-1|CAF18565.1| 1685|Homo sapiens myomesin 1 protein. 48 2e-04
AF214114-1|AAF28341.2| 1226|Homo sapiens retinoblastoma-binding ... 48 2e-04
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 48 3e-04
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 48 3e-04
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 48 3e-04
AY533564-1|AAS45545.2| 2039|Homo sapiens ankyrin repeat-containi... 48 3e-04
AY373757-1|AAR25662.1| 2062|Homo sapiens ankyrin repeat-containi... 48 3e-04
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 48 3e-04
AK125322-1|BAC86128.1| 1685|Homo sapiens protein ( Homo sapiens ... 48 3e-04
AF317425-1|AAG38609.1| 2062|Homo sapiens GAC-1 protein. 48 3e-04
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 48 4e-04
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 47 6e-04
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 47 6e-04
BC094834-1|AAH94834.1| 727|Homo sapiens MAP1B protein protein. 47 6e-04
AY168345-1|AAN86963.1| 2464|Homo sapiens retinitis pigmentosa 1-... 47 6e-04
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 47 8e-04
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 47 8e-04
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 47 8e-04
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 47 8e-04
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 47 8e-04
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 47 8e-04
AY358132-1|AAQ88499.1| 352|Homo sapiens DMML2433 protein. 47 8e-04
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 47 8e-04
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 47 8e-04
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 47 8e-04
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 47 8e-04
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 47 8e-04
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 47 8e-04
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 47 8e-04
AB031547-1|BAA95681.1| 623|Homo sapiens retina specific protein... 47 8e-04
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 46 0.001
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 46 0.001
M83216-1|AAA58419.1| 793|Homo sapiens caldesmon protein. 46 0.001
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 46 0.001
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 46 0.001
BX538014-1|CAD97961.1| 355|Homo sapiens hypothetical protein pr... 46 0.001
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 46 0.001
BC036771-1|AAH36771.1| 226|Homo sapiens NEGR1 protein protein. 46 0.001
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 46 0.001
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 46 0.001
AY328482-1|AAP97010.1| 571|Homo sapiens MAM domain containing 1... 46 0.001
AY168346-1|AAN86964.1| 2480|Homo sapiens retinitis pigmentosa 1-... 46 0.001
AL645724-1|CAI21858.1| 354|Homo sapiens neuronal growth regulat... 46 0.001
AL627317-2|CAH72392.1| 226|Homo sapiens neuronal growth regulat... 46 0.001
AL627317-1|CAH72391.1| 354|Homo sapiens neuronal growth regulat... 46 0.001
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 46 0.001
AL359821-2|CAH70914.1| 226|Homo sapiens neuronal growth regulat... 46 0.001
AL359821-1|CAH70913.1| 354|Homo sapiens neuronal growth regulat... 46 0.001
AL356600-2|CAI23493.1| 226|Homo sapiens neuronal growth regulat... 46 0.001
AL356600-1|CAI23492.1| 354|Homo sapiens neuronal growth regulat... 46 0.001
AL354949-2|CAI16870.1| 226|Homo sapiens neuronal growth regulat... 46 0.001
AL354949-1|CAI16869.1| 354|Homo sapiens neuronal growth regulat... 46 0.001
AK131423-1|BAD18570.1| 596|Homo sapiens protein ( Homo sapiens ... 46 0.001
AJ491324-1|CAD36957.1| 2464|Homo sapiens retinitis pigmentosa 1-... 46 0.001
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 46 0.001
AF078035-1|AAD16006.1| 1220|Homo sapiens translation initiation ... 46 0.001
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 46 0.001
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 46 0.001
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 46 0.001
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 46 0.001
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 46 0.001
BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein. 46 0.001
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 46 0.001
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 46 0.001
BC100788-1|AAI00789.1| 467|Homo sapiens C9orf94 protein protein. 46 0.001
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 46 0.001
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 46 0.001
AF208045-1|AAF23433.3| 1213|Homo sapiens breast cancer-associate... 46 0.001
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 46 0.002
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 46 0.002
L05606-1|AAA36339.1| 476|Homo sapiens protein ( Human myosin bi... 46 0.002
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 46 0.002
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 46 0.002
AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens ... 46 0.002
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 46 0.002
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 46 0.002
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 45 0.002
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 45 0.002
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 45 0.002
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 45 0.002
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 45 0.002
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 45 0.002
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 45 0.002
BC046109-1|AAH46109.1| 459|Homo sapiens PTK7 protein protein. 45 0.002
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 45 0.002
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 45 0.002
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 45 0.002
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 45 0.002
AK092307-1|BAC03858.1| 354|Homo sapiens protein ( Homo sapiens ... 45 0.002
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 45 0.002
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 45 0.002
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 45 0.002
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 45 0.002
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 45 0.002
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 45 0.002
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 45 0.002
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 45 0.002
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 45 0.002
Y00067-1|CAA68276.1| 916|Homo sapiens NF-M protein. 45 0.003
BC139918-1|AAI39919.1| 726|Homo sapiens Unknown (protein for IM... 45 0.003
BC013955-1|AAH13955.2| 365|Homo sapiens FGFRL1 protein protein. 45 0.003
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 45 0.003
AK096821-1|BAC04869.1| 405|Homo sapiens protein ( Homo sapiens ... 45 0.003
AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens ... 45 0.003
AC023270-2|AAX88845.1| 405|Homo sapiens unknown protein. 45 0.003
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 45 0.003
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 44 0.004
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 44 0.004
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 44 0.004
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 44 0.004
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 44 0.004
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 44 0.004
D90452-1|BAA14418.1| 558|Homo sapiens l-caldesmon I protein. 44 0.004
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 44 0.004
BC113387-1|AAI13388.1| 248|Homo sapiens hypothetical protein FL... 44 0.004
BC113385-1|AAI13386.1| 248|Homo sapiens hypothetical protein FL... 44 0.004
BC096757-1|AAH96757.1| 916|Homo sapiens neurofilament, medium p... 44 0.004
BC080185-1|AAH80185.1| 417|Homo sapiens SMC1A protein protein. 44 0.004
AY358142-1|AAQ88509.1| 576|Homo sapiens Bikunin hlg protein. 44 0.004
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 44 0.004
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 44 0.004
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 44 0.004
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 44 0.004
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 44 0.004
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 44 0.004
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 44 0.004
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 44 0.004
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 44 0.004
AL009173-2|CAI42611.1| 248|Homo sapiens novel protein protein. 44 0.004
AK094978-1|BAC04467.1| 248|Homo sapiens protein ( Homo sapiens ... 44 0.004
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 44 0.004
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 44 0.004
AF468657-1|AAL77058.1| 576|Homo sapiens multivalent protease in... 44 0.004
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 44 0.004
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 44 0.004
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 44 0.004
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 44 0.004
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 44 0.004
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 44 0.005
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 44 0.005
M64110-1|AAA35636.1| 538|Homo sapiens caldesmon protein. 44 0.005
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 44 0.005
AL158150-1|CAM14351.1| 275|Homo sapiens chromosome 9 open readi... 44 0.005
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 44 0.005
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 44 0.005
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 44 0.007
M83216-2|AAA58420.1| 538|Homo sapiens caldesmon protein. 44 0.007
D90453-1|BAA14419.1| 532|Homo sapiens l-caldesmon II protein. 44 0.007
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 44 0.007
BC040354-1|AAH40354.1| 538|Homo sapiens caldesmon 1 protein. 44 0.007
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 44 0.007
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 44 0.007
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 44 0.007
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 44 0.007
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 44 0.007
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 44 0.007
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 44 0.007
AF247820-1|AAF69498.3| 481|Homo sapiens NAG22 protein protein. 44 0.007
AF044209-1|AAC33550.1| 2440|Homo sapiens nuclear receptor co-rep... 44 0.007
U72849-1|AAD00186.1| 2033|Homo sapiens envoplakin protein. 43 0.009
U53786-1|AAC64662.1| 2033|Homo sapiens envoplakin protein. 43 0.009
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 43 0.009
M63702-1|AAA52179.1| 94|Homo sapiens DCC protein. 43 0.009
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 43 0.009
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 43 0.009
BC126105-1|AAI26106.1| 2033|Homo sapiens envoplakin protein. 43 0.009
BC126103-1|AAI26104.1| 2033|Homo sapiens envoplakin protein. 43 0.009
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 43 0.009
BC114334-1|AAI14335.2| 280|Homo sapiens NRG2 protein protein. 43 0.009
BC114333-1|AAI14334.2| 280|Homo sapiens NRG2 protein protein. 43 0.009
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 43 0.009
BC103984-1|AAI03985.2| 280|Homo sapiens NRG2 protein protein. 43 0.009
BC103983-1|AAI03984.2| 280|Homo sapiens NRG2 protein protein. 43 0.009
BC080541-1|AAH80541.1| 393|Homo sapiens ROR1 protein protein. 43 0.009
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 43 0.009
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 43 0.009
AL513328-3|CAI17351.1| 116|Homo sapiens muscle, skeletal, recep... 43 0.009
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 43 0.009
AL445205-1|CAH71705.1| 393|Homo sapiens receptor tyrosine kinas... 43 0.009
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 43 0.009
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 43 0.009
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 43 0.009
AL161742-1|CAI21931.1| 393|Homo sapiens receptor tyrosine kinas... 43 0.009
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 43 0.009
AL137859-1|CAC17591.2| 393|Homo sapiens receptor tyrosine kinas... 43 0.009
AL096857-1|CAB51071.1| 2701|Homo sapiens hypothetical protein pr... 43 0.009
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 43 0.009
AF488829-1|AAO49478.1| 2701|Homo sapiens HBxAg transactivated pr... 43 0.009
AF119162-4|AAF28849.1| 844|Homo sapiens neuregulin 2 isoform 2 ... 43 0.009
AF119162-3|AAF28851.1| 852|Homo sapiens neuregulin 2 isoform 4 ... 43 0.009
AF119162-2|AAF28848.1| 850|Homo sapiens neuregulin 2 isoform 1 ... 43 0.009
AF119162-1|AAF28850.1| 858|Homo sapiens neuregulin 2 isoform 3 ... 43 0.009
AF119158-1|AAF28852.1| 426|Homo sapiens neuregulin 2 isoform 5 ... 43 0.009
AF119157-1|AAF28853.1| 422|Homo sapiens neuregulin 2 isoform 6 ... 43 0.009
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 43 0.009
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 43 0.009
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 43 0.009
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 43 0.009
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 43 0.009
AB005060-1|BAA23417.1| 850|Homo sapiens NTAK protein. 43 0.009
X64699-1|CAA45940.1| 531|Homo sapiens titin protein. 43 0.012
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 43 0.012
L02320-1|AAA36541.1| 583|Homo sapiens radixin protein. 43 0.012
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 43 0.012
BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein. 43 0.012
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 43 0.012
BC039828-1|AAH39828.1| 1091|Homo sapiens structural maintenance ... 43 0.012
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 43 0.012
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 43 0.012
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 43 0.012
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 43 0.012
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 43 0.012
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 43 0.012
AF092564-1|AAC72361.1| 1202|Homo sapiens chromosome-associated p... 43 0.012
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 43 0.012
AC097377-2|AAX88851.1| 1091|Homo sapiens unknown protein. 43 0.012
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 43 0.012
AB019987-1|BAA73535.1| 1288|Homo sapiens chromosome-associated p... 43 0.012
BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein. 42 0.016
AL451075-1|CAI12671.1| 1012|Homo sapiens chromosome 1 open readi... 42 0.016
>AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform
protein.
Length = 2154
Score = 129 bits (312), Expect = 8e-29
Identities = 98/336 (29%), Positives = 149/336 (44%), Gaps = 19/336 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P VL L+ TV G+ I GRP PKI W+ E+L+ T
Sbjct: 793 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 852
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I EAFPE A +Y C A N +G +T L++E VP V D ++ +
Sbjct: 853 LLI-EAFPEDAAVYTCEAKNDYGVATTSASLSVE----VPEVVSPD-------QEMPVYP 900
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P I+ L VT+ EG+ R + + G +V W + ++ S +++ + +D T L
Sbjct: 901 PAIITPLQDTVTS-EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQL 957
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK-PEWVTHMEELQAALKA 1518
+ E Y +D G F A N +G ++ A LS+E +E +W + + +
Sbjct: 958 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLS-VSFKKEP 1016
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI--RTDERFIIENKEN 1576
P+F++ + RVH E V F A SG P PEI W+ + ++I D F E
Sbjct: 1017 LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTG 1076
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A + G Y+CKA + G A A L V
Sbjct: 1077 MALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 1112
Score = 95.9 bits (228), Expect = 1e-18
Identities = 80/315 (25%), Positives = 146/315 (46%), Gaps = 24/315 (7%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGD------APLVLAPLENTTVMDGERISLNCK 1304
V TC A+N G +TS S VE + D P ++ PL++T +G+ C+
Sbjct: 864 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR 923
Query: 1305 ILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
+ G K+ W+ +K I+ +R ++ Q ++ I EA+PE G Y ASN G+
Sbjct: 924 VSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 981
Query: 1365 STECILNIEA---YEYVPSVSEEDV-LSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRL 1420
S+ L++E +E S S+ V LS + P ++ L + + G+ +R
Sbjct: 982 SSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSS-LRVHNGETVRF 1040
Query: 1421 EAKAIGIPKPQVRWLRQGTELLQSTE--YQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
A+ GIPKP+++W +L + + + EE G +++ + + Y + G+ +A N
Sbjct: 1041 HARVSGIPKPEIQWFHNQQLILPTKDVVFHFEE-STGMALMLIVDAYSEHAGQYSCKAAN 1099
Query: 1479 HLGVTATIAALSV-----ESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
G A L+V ESI+ E + E M+E ++ + + E+ +
Sbjct: 1100 SAGEATCAATLTVTPKAPESIL--HERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 1157
Query: 1534 VHEE-EIVTFEAIYS 1547
++E E+++ +YS
Sbjct: 1158 INETLELLSESPVYS 1172
Score = 85.0 bits (201), Expect = 2e-15
Identities = 69/244 (28%), Positives = 108/244 (44%), Gaps = 18/244 (7%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E + +SE V S + S+ E P +K + + G + L IGIPKP+++W
Sbjct: 1160 ETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNA-DISMGDVATLSVTVIGIPKPKIQWF 1218
Query: 1436 RQGTELLQSTEYQ-IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
G L S +Y+ + + DD + I+ ++ +D GE A N G T A L + S
Sbjct: 1219 FNGVLLTPSADYKFVFDGDDHSLIILFTKL--EDEGEYTCMASNDYGKTICSAYLKINS- 1275
Query: 1495 VGTQEYRKPEWVTHMEELQAALKATQSV-----PTFVKEIIPERVHEEEIVTFEAIYSGN 1549
K E E A K+ + + P F+KE+ P R + FE G
Sbjct: 1276 -------KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 1328
Query: 1550 PTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P P + W+K+NK + T + II N T + ++ G Y CKA + +G + A
Sbjct: 1329 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 1388
Query: 1609 KLQV 1612
+L V
Sbjct: 1389 ELLV 1392
Score = 72.9 bits (171), Expect = 1e-11
Identities = 56/217 (25%), Positives = 92/217 (42%), Gaps = 7/217 (3%)
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+G P+ + + N + G+ +L+ ++G P PKI WF N L+ + D
Sbjct: 1180 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 1239
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGK--CSTECILNIEAYEYVPSVSEEDVLSD-EKTSD 1394
I + E G Y C ASN +GK CS +N + + + +E V EK
Sbjct: 1240 SLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 1298
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
P +K L + +G E +G P P V W ++ +L S Y I +
Sbjct: 1299 --PCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 1355
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
G+ + + ++D+G + +A N LG + A L V
Sbjct: 1356 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 1392
Score = 55.6 bits (128), Expect = 2e-06
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 10/132 (7%)
Query: 1492 ESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP-------ERVHEEEIVTFEA 1544
ES+ ++E + + EE+ A +K ++ F+KE P + V EE +
Sbjct: 1932 ESLKPSEEKEESSSESGTEEV-ATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLT 1990
Query: 1545 IYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKA-TKDLEGTYTCKAVSDIGL 1603
N E+ WY +NK++ +DE+F +N T I K T+D +G Y C+A++D G
Sbjct: 1991 TSITN-AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGK 2049
Query: 1604 AVTKAKLQVFQR 1615
T AKL V +R
Sbjct: 2050 TATSAKLTVVKR 2061
Score = 44.0 bits (99), Expect = 0.005
Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 6/134 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
V+++ ++D G C A N +G +TS V ++ AP++ +E V G
Sbjct: 2026 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA-----APVIKRKIEPLEVALGHL 2080
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
C+I P + WF + I + +I R + + I G Y C AS
Sbjct: 2081 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 2139
Query: 1359 NQFGKCSTECILNI 1372
N++G S L +
Sbjct: 2140 NEYGSVSCTATLTV 2153
Score = 40.7 bits (91), Expect = 0.050
Identities = 45/215 (20%), Positives = 80/215 (37%), Gaps = 26/215 (12%)
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I D P++ PL +T +G+ + L I +++W+ KL+ + + ++
Sbjct: 1965 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA--KEVNWYFENKLVPSDEKFKCLQDQNT 2022
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ K + G Y C A N GK +T L + V+
Sbjct: 2023 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV----------------------VK 2060
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
AP ++K + G L + + P + +W + G E+ +S + I
Sbjct: 2061 RAAP-VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS-SKYI 2118
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
S L + D GE +A N G + A L+V
Sbjct: 2119 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 2153
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 114 bits (275), Expect = 3e-24
Identities = 83/261 (31%), Positives = 129/261 (49%), Gaps = 15/261 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C A N G VS S + VE ++ AP + L++ V++G+ L C + G P
Sbjct: 483 GTYSCTASNAQGQVSCSWTLQVERLAVMEV-APSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I W N + I+ AR S ++G+ E+HI++A PE G Y C A N G+ S C
Sbjct: 542 VPRITWLLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENALGQVS--CS 595
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+ +E S E +L + + AP ++ L + + +G + + + G P
Sbjct: 596 AWVTVHEKKSSRKSEYLL---PVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGNPP 651
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P+V WL G E+ +S ++ E+ S L + EV+ +DTG EA+N G T A L
Sbjct: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHS-LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
Query: 1490 SV-ESIVGTQEY--RKPEWVT 1507
+V E GTQ + KP VT
Sbjct: 711 TVQEPHDGTQPWFISKPRSVT 731
Score = 88.6 bits (210), Expect = 2e-16
Identities = 80/324 (24%), Positives = 133/324 (41%), Gaps = 32/324 (9%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
++ V + + + C++ G P P++ WF + + +G + + +A
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLCLLKARTR 480
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y CTASN G+ S L +E V E AP L
Sbjct: 481 DSGTYSCTASNAQGQVSCSWTLQVERLA------------------VMEVAPSFSSVLKD 522
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
EG+ L+ G P P++ WL G Q +Y + G + L + + +D
Sbjct: 523 CAVI-EGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEAGVAELHIQDALPED 577
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKE 1528
G A N LG + A ++V + RK E++ + A K T P F++
Sbjct: 578 HGTYTCLAENALGQVSCSAWVTVHE---KKSSRKSEYLLPV----APSKPT--APIFLQG 628
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ +V + VT SGNP PE++W + I+ E F E + + + I++ +
Sbjct: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
GTYTC+A + G T+A L V
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTV 712
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 6/212 (2%)
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P + EG + E + G P+PQV W R G + + ++ GT L + V++
Sbjct: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA-ALKATQSV--- 1522
+D G+ EA N G L+VE Q + T + A A++ S+
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGE 158
Query: 1523 --PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F ++ V E ++ F +G P P++ W K N ++ R + K
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +D G YTC V+ G A A+L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 73.7 bits (173), Expect = 6e-12
Identities = 68/263 (25%), Positives = 119/263 (45%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 1064 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A PE G+YKC A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKND 1175
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ +S ++E ++G S
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG-SK 1294
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 1295 LTILAARQEHCGCYTLLVENKLG 1317
Score = 70.5 bits (165), Expect = 5e-11
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 12/225 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + P N + +G ++ G P P++ W N + I + + G
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV---LSDEKTSDVE 1396
+ I E G Y C A+N G L +E + + + V L D ++
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQPVVSKTLGDRFSASAV 149
Query: 1397 EFAPRIVKALPTV-------VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E P I P V EG++ R K G P+PQV WL+ L S +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E +G +L + V QDD G N G + A LS++ +
Sbjct: 210 SE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
Score = 69.3 bits (162), Expect = 1e-10
Identities = 94/374 (25%), Positives = 143/374 (38%), Gaps = 44/374 (11%)
Query: 1268 SSIVEEQTCIDGDAPLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR 1326
+S VE + I G+ P A L V +G+ +CKI GRP P++ W ++ +
Sbjct: 146 ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
Query: 1327 DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV 1386
+++S +K+G+ + I + G+Y C N GK S L+I+ + S + V
Sbjct: 206 RVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD---SANRSFV 261
Query: 1387 LSDEKT-SDVEEFAPRIVKALPTVVTTTEGKLIRLE--AKAIGIPKPQ----VRWLRQGT 1439
+ T SDV + T V + E KL LE AK+ PQ W +
Sbjct: 262 RETKATNSDVRKEV--------TNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW-AANS 312
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ E ++E D V Q + I +A + L V S G +
Sbjct: 313 QPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA-ARVQPEPRAPGLGVLSPSGEER 371
Query: 1500 YR-KPEWVTHMEELQAALKATQSVPTFVKEIIP-------------ERVHEEEI-----V 1540
R P Q L + V IP + +E+ V
Sbjct: 372 KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTV 431
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFI--IENKENRTTCTIKKATKDLEGTYTCKAV 1598
F SG P PE+ W+ + +R E I EN + C +K T+D GTY+C A
Sbjct: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLCLLKARTRD-SGTYSCTAS 490
Query: 1599 SDIGLAVTKAKLQV 1612
+ G LQV
Sbjct: 491 NAQGQVSCSWTLQV 504
Score = 57.6 bits (133), Expect = 4e-07
Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V T V+E DG P ++ + T G+ + ++C I G P
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+P + W + K + Q + + +K+ P AG Y+ N+ G+CS +
Sbjct: 749 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 1370 LNIE 1373
L ++
Sbjct: 809 LMLQ 812
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 1781 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 1835
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 1836 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1895
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 1896 ELIVETM 1902
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 1087 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 1144
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 1265 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324
Query: 1610 LQVFQR 1615
L V +
Sbjct: 1325 LTVVDK 1330
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 114 bits (275), Expect = 3e-24
Identities = 83/261 (31%), Positives = 129/261 (49%), Gaps = 15/261 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C A N G VS S + VE ++ AP + L++ V++G+ L C + G P
Sbjct: 483 GTYSCTASNAQGQVSCSWTLQVERLAVMEV-APSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I W N + I+ AR S ++G+ E+HI++A PE G Y C A N G+ S C
Sbjct: 542 VPRITWLLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENALGQVS--CS 595
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+ +E S E +L + + AP ++ L + + +G + + + G P
Sbjct: 596 AWVTVHEKKSSRKSEYLL---PVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGNPP 651
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P+V WL G E+ +S ++ E+ S L + EV+ +DTG EA+N G T A L
Sbjct: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHS-LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
Query: 1490 SV-ESIVGTQEY--RKPEWVT 1507
+V E GTQ + KP VT
Sbjct: 711 TVQEPHDGTQPWFISKPRSVT 731
Score = 88.2 bits (209), Expect = 3e-16
Identities = 80/324 (24%), Positives = 133/324 (41%), Gaps = 32/324 (9%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
++ V + + + C++ G P P++ WF + + +G + + +A
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y CTASN G+ S L +E V E AP L
Sbjct: 481 DSGTYSCTASNAQGQVSCSWTLQVERLA------------------VMEVAPSFSSVLKD 522
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
EG+ L+ G P P++ WL G Q +Y + G + L + + +D
Sbjct: 523 CAVI-EGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEAGVAELHIQDALPED 577
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKE 1528
G A N LG + A ++V + RK E++ + A K T P F++
Sbjct: 578 HGTYTCLAENALGQVSCSAWVTVHE---KKSSRKSEYLLPV----APSKPT--APIFLQG 628
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ +V + VT SGNP PE++W + I+ E F E + + + I++ +
Sbjct: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
GTYTC+A + G T+A L V
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTV 712
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 6/212 (2%)
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P + EG + E + G P+PQV W R G + + ++ GT L + V++
Sbjct: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA-ALKATQSV--- 1522
+D G+ EA N G L+VE Q + T + A A++ S+
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGE 158
Query: 1523 --PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F ++ V E ++ F +G P P++ W K N ++ R + K
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +D G YTC V+ G A A+L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 73.7 bits (173), Expect = 6e-12
Identities = 68/263 (25%), Positives = 119/263 (45%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 1064 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A PE G+YKC A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKND 1175
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ +S ++E ++G S
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG-SK 1294
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 1295 LTILAARQEHCGCYTLLVENKLG 1317
Score = 70.5 bits (165), Expect = 5e-11
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 12/225 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + P N + +G ++ G P P++ W N + I + + G
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV---LSDEKTSDVE 1396
+ I E G Y C A+N G L +E + + + V L D ++
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQPVVSKTLGDRFSASAV 149
Query: 1397 EFAPRIVKALPTV-------VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E P I P V EG++ R K G P+PQV WL+ L S +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E +G +L + V QDD G N G + A LS++ +
Sbjct: 210 SE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
Score = 67.3 bits (157), Expect = 5e-10
Identities = 93/374 (24%), Positives = 143/374 (38%), Gaps = 44/374 (11%)
Query: 1268 SSIVEEQTCIDGDAPLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR 1326
+S VE + I G+ P A L V +G+ +CKI GRP P++ W ++ +
Sbjct: 146 ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
Query: 1327 DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV 1386
+++S +K+G+ + I + G+Y C N GK S L+I+ + S + V
Sbjct: 206 RVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD---SANRSFV 261
Query: 1387 LSDEKT-SDVEEFAPRIVKALPTVVTTTEGKLIRLE--AKAIGIPKPQ----VRWLRQGT 1439
+ T SDV + T V + E KL LE AK+ PQ W +
Sbjct: 262 RETKATNSDVRKEV--------TNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW-AANS 312
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ E ++E D V Q + I +A + L V S G +
Sbjct: 313 QPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA-ARVQPEPRAPGLGVLSPSGEER 371
Query: 1500 YR-KPEWVTHMEELQAALKATQSVPTFVKEIIP-------------ERVHEEEI-----V 1540
R P Q L + V IP + +E+ V
Sbjct: 372 KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTV 431
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFI--IENKENRTTCTIKKATKDLEGTYTCKAV 1598
F SG P PE+ W+ + +R E I E+ + C +K T+D GTY+C A
Sbjct: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTAS 490
Query: 1599 SDIGLAVTKAKLQV 1612
+ G LQV
Sbjct: 491 NAQGQVSCSWTLQV 504
Score = 57.6 bits (133), Expect = 4e-07
Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V T V+E DG P ++ + T G+ + ++C I G P
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+P + W + K + Q + + +K+ P AG Y+ N+ G+CS +
Sbjct: 749 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 1370 LNIE 1373
L ++
Sbjct: 809 LMLQ 812
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 1781 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 1835
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 1836 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1895
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 1896 ELIVETM 1902
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 1087 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 1144
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 1265 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324
Query: 1610 LQVFQR 1615
L V +
Sbjct: 1325 LTVVDK 1330
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 114 bits (274), Expect = 3e-24
Identities = 83/261 (31%), Positives = 129/261 (49%), Gaps = 15/261 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C A N G VS S + VE ++ AP + L++ V++G+ L C + G P
Sbjct: 483 GTYSCTASNAQGQVSCSWTLQVERLAVMEV-APSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I W N + I+ AR S ++G+ E+HI++A PE G Y C A N G+ S C
Sbjct: 542 VPRITWLLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENALGQVS--CS 595
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+ +E S E +L + + AP ++ L + + +G + + + G P
Sbjct: 596 AWVTVHEKKSSRKSEYLL---PVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGNPP 651
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P+V WL G E+ +S ++ E+ S L + EV+ +DTG EA+N G T A L
Sbjct: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHS-LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
Query: 1490 SV-ESIVGTQEY--RKPEWVT 1507
+V E GTQ + KP VT
Sbjct: 711 TVQEPHDGTQPWFISKPRSVT 731
Score = 87.8 bits (208), Expect = 3e-16
Identities = 80/324 (24%), Positives = 133/324 (41%), Gaps = 32/324 (9%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
++ V + + + C++ G P P++ WF + + +G + + +A
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y CTASN G+ S L +E V E AP L
Sbjct: 481 DSGTYSCTASNAQGQVSCSWTLQVERLA------------------VMEVAPSFSSVLKD 522
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
EG+ L+ G P P++ WL G Q +Y + G + L + + +D
Sbjct: 523 CAVI-EGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEAGVAELHIQDALPED 577
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKE 1528
G A N LG + A ++V + RK E++ + A K T P F++
Sbjct: 578 HGTYTCLAENALGQVSCSAWVTVHE---KKSSRKSEYLLPV----APSKPT--APIFLQG 628
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ +V + VT SGNP PE++W + I+ E F E + + + I++ +
Sbjct: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPE 688
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
GTYTC+A + G T+A L V
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTV 712
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 6/212 (2%)
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P + EG + E + G P+PQV W R G + + ++ GT L + V++
Sbjct: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA-ALKATQSV--- 1522
+D G+ EA N G L+VE Q + T + A A++ S+
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGE 158
Query: 1523 --PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F ++ V E ++ F +G P P++ W K N ++ R + K
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +D G YTC V+ G A A+L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 73.7 bits (173), Expect = 6e-12
Identities = 68/263 (25%), Positives = 119/263 (45%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 1064 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A PE G+YKC A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKND 1175
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ +S ++E ++G S
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG-SK 1294
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 1295 LTILAARQEHCGCYTLLVENKLG 1317
Score = 70.5 bits (165), Expect = 5e-11
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 12/225 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + P N + +G ++ G P P++ W N + I + + G
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV---LSDEKTSDVE 1396
+ I E G Y C A+N G L +E + + + V L D ++
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQPVVSKTLGDRFSASAV 149
Query: 1397 EFAPRIVKALPTV-------VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E P I P V EG++ R K G P+PQV WL+ L S +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E +G +L + V QDD G N G + A LS++ +
Sbjct: 210 SE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
Score = 67.3 bits (157), Expect = 5e-10
Identities = 93/374 (24%), Positives = 143/374 (38%), Gaps = 44/374 (11%)
Query: 1268 SSIVEEQTCIDGDAPLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR 1326
+S VE + I G+ P A L V +G+ +CKI GRP P++ W ++ +
Sbjct: 146 ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
Query: 1327 DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV 1386
+++S +K+G+ + I + G+Y C N GK S L+I+ + S + V
Sbjct: 206 RVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD---SANRSFV 261
Query: 1387 LSDEKT-SDVEEFAPRIVKALPTVVTTTEGKLIRLE--AKAIGIPKPQ----VRWLRQGT 1439
+ T SDV + T V + E KL LE AK+ PQ W +
Sbjct: 262 RETKATNSDVRKEV--------TNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW-AANS 312
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ E ++E D V Q + I +A + L V S G +
Sbjct: 313 QPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA-ARVQPEPRAPGLGVLSPSGEER 371
Query: 1500 YR-KPEWVTHMEELQAALKATQSVPTFVKEIIP-------------ERVHEEEI-----V 1540
R P Q L + V IP + +E+ V
Sbjct: 372 KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTV 431
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFI--IENKENRTTCTIKKATKDLEGTYTCKAV 1598
F SG P PE+ W+ + +R E I E+ + C +K T+D GTY+C A
Sbjct: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTAS 490
Query: 1599 SDIGLAVTKAKLQV 1612
+ G LQV
Sbjct: 491 NAQGQVSCSWTLQV 504
Score = 57.6 bits (133), Expect = 4e-07
Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V T V+E DG P ++ + T G+ + ++C I G P
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+P + W + K + Q + + +K+ P AG Y+ N+ G+CS +
Sbjct: 749 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 1370 LNIE 1373
L ++
Sbjct: 809 LMLQ 812
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 1781 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 1835
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 1836 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1895
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 1896 ELIVETM 1902
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1912
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 1087 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 1144
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 1265 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324
Query: 1610 LQVFQR 1615
L V +
Sbjct: 1325 LTVVDK 1330
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 114 bits (274), Expect = 3e-24
Identities = 83/261 (31%), Positives = 129/261 (49%), Gaps = 15/261 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C A N G VS S + VE ++ AP + L++ V++G+ L C + G P
Sbjct: 483 GTYSCTASNAQGQVSCSWTLQVERLAVMEV-APSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I W N + I+ AR S ++G+ E+HI++A PE G Y C A N G+ S C
Sbjct: 542 VPRITWLLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENALGQVS--CS 595
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+ +E S E +L + + AP ++ L + + +G + + + G P
Sbjct: 596 AWVTVHEKKSSRKSEYLL---PVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGNPP 651
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P+V WL G E+ +S ++ E+ S L + EV+ +DTG EA+N G T A L
Sbjct: 652 PEVIWLHNGNEIQESEDFHFEQRGTQHS-LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
Query: 1490 SV-ESIVGTQEY--RKPEWVT 1507
+V E GTQ + KP VT
Sbjct: 711 TVQEPHDGTQPWFISKPRSVT 731
Score = 87.8 bits (208), Expect = 3e-16
Identities = 80/324 (24%), Positives = 133/324 (41%), Gaps = 32/324 (9%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
++ V + + + C++ G P P++ WF + + +G + + +A
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y CTASN G+ S L +E V E AP L
Sbjct: 481 DSGTYSCTASNAQGQVSCSWTLQVERLA------------------VMEVAPSFSSVLKD 522
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
EG+ L+ G P P++ WL G Q +Y + G + L + + +D
Sbjct: 523 CAVI-EGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEAGVAELHIQDALPED 577
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKE 1528
G A N LG + A ++V + RK E++ + A K T P F++
Sbjct: 578 HGTYTCLAENALGQVSCSAWVTVHE---KKSSRKSEYLLPV----APSKPT--APIFLQG 628
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ +V + VT SGNP PE++W + I+ E F E + + + I++ +
Sbjct: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPE 688
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
GTYTC+A + G T+A L V
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTV 712
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 6/212 (2%)
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P + EG + E + G P+PQV W R G + + ++ GT L + V++
Sbjct: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA-ALKATQSV--- 1522
+D G+ EA N G L+VE Q + T + A A++ S+
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGE 158
Query: 1523 --PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F ++ V E ++ F +G P P++ W K N ++ R + K
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +D G YTC V+ G A A+L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 70.5 bits (165), Expect = 5e-11
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 12/225 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + P N + +G ++ G P P++ W N + I + + G
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV---LSDEKTSDVE 1396
+ I E G Y C A+N G L +E + + + V L D ++
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQPVVSKTLGDRFSASAV 149
Query: 1397 EFAPRIVKALPTV-------VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E P I P V EG++ R K G P+PQV WL+ L S +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E +G +L + V QDD G N G + A LS++ +
Sbjct: 210 SE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
Score = 68.9 bits (161), Expect = 2e-10
Identities = 67/263 (25%), Positives = 117/263 (44%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 1064 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A E G+YKC A N
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALLEDRGLYKCVAKND 1175
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ S ++E ++G S
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENG-SK 1294
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 1295 LTILAARQEHCGCYTLLVENKLG 1317
Score = 67.3 bits (157), Expect = 5e-10
Identities = 93/374 (24%), Positives = 143/374 (38%), Gaps = 44/374 (11%)
Query: 1268 SSIVEEQTCIDGDAPLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR 1326
+S VE + I G+ P A L V +G+ +CKI GRP P++ W ++ +
Sbjct: 146 ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
Query: 1327 DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV 1386
+++S +K+G+ + I + G+Y C N GK S L+I+ + S + V
Sbjct: 206 RVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD---SANRSFV 261
Query: 1387 LSDEKT-SDVEEFAPRIVKALPTVVTTTEGKLIRLE--AKAIGIPKPQ----VRWLRQGT 1439
+ T SDV + T V + E KL LE AK+ PQ W +
Sbjct: 262 RETKATNSDVRKEV--------TNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW-AANS 312
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ E ++E D V Q + I +A + L V S G +
Sbjct: 313 QPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA-ARVQPEPRAPGLGVLSPSGEER 371
Query: 1500 YR-KPEWVTHMEELQAALKATQSVPTFVKEIIP-------------ERVHEEEI-----V 1540
R P Q L + V IP + +E+ V
Sbjct: 372 KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTV 431
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFI--IENKENRTTCTIKKATKDLEGTYTCKAV 1598
F SG P PE+ W+ + +R E I E+ + C +K T+D GTY+C A
Sbjct: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTAS 490
Query: 1599 SDIGLAVTKAKLQV 1612
+ G LQV
Sbjct: 491 NAQGQVSCSWTLQV 504
Score = 57.6 bits (133), Expect = 4e-07
Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 2/124 (1%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V T V+E DG P ++ + T G+ + ++C I G P
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+P + W + K + Q + + +K+ P AG Y+ N+ G+CS +
Sbjct: 749 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 1370 LNIE 1373
L ++
Sbjct: 809 LMLQ 812
Score = 54.4 bits (125), Expect = 4e-06
Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 1757 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1816
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
I D + YTCKAV+ +G A A+
Sbjct: 1817 ISDVCGDDDAKYTCKAVNSLGEATCTAE 1844
Score = 52.4 bits (120), Expect = 2e-05
Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 1729 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 1783
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 1784 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1843
Query: 1488 ALSVESI 1494
VE++
Sbjct: 1844 EHIVETM 1850
Score = 49.6 bits (113), Expect = 1e-04
Identities = 26/104 (25%), Positives = 45/104 (43%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 1757 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1816
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + +E E EE+
Sbjct: 1817 ISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGEGEEE 1860
Score = 46.0 bits (104), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 1087 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 1144
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 1145 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 1265 QPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1324
Query: 1610 LQVFQR 1615
L V +
Sbjct: 1325 LTVVDK 1330
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 104 bits (249), Expect = 4e-21
Identities = 89/355 (25%), Positives = 150/355 (42%), Gaps = 36/355 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP+ L L+N V DG +S +C + G+P P + WF + KL+E I+ + G ++
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI-----------EAYEYVPSVSEEDVLSD 1389
I P G+Y+C A N G ST+ L + +A E S + LS
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 1390 ------EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E T+D E P++V+ L + +L + + K G P P++ W + G L
Sbjct: 5245 REQEGTESTTD-EGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTA 5303
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
S ++ + L + V ++D+G+ N +G + A L V +E KP
Sbjct: 5304 SAHIRMTD-KKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE--KP 5360
Query: 1504 EWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKV- 1562
H E+L P ++ P++V + +TF G P P + W ++
Sbjct: 5361 ASDVH-EQLVP--------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 1563 ----IRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + + + + + + + +GTYTC A + G A+ A L V
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 73.7 bits (173), Expect = 6e-12
Identities = 76/331 (22%), Positives = 129/331 (38%), Gaps = 30/331 (9%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP L + V G+ +L+C+I+G P P++ W +++ + ++ Q L +
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA-QDGDLYRL 67
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
I + +G Y C A N G+ L ++A + E AP
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-----------------EAACAEQAP 110
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ--STEYQIEELDDGTSI 1458
+ PT + EG + G P+P V W + G L + ++EEL + S
Sbjct: 111 HFLLR-PTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEA-SA 168
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK----PEWVTHMEELQA 1514
L + D G A N LG + AAL V+S R + H++ +
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228
Query: 1515 ALKATQSVPTFVKEIIPER--VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII- 1571
A++A + P V E + +G P PE +W KD +++ R ++
Sbjct: 229 AMRA-EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVY 287
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E+ + I + G YTC A + +G
Sbjct: 288 EDAQENFVLKILFCKQSDRGLYTCTASNLVG 318
Score = 69.3 bits (162), Expect = 1e-10
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 39/357 (10%)
Query: 1250 GVVTCRAENFAGSVSTS-GSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N G + G + E C + AP L + V +G + C++ G
Sbjct: 78 GQYVCRARNAIGEAFAAVGLQVDAEAACAE-QAPHFLLRPTSIRVREGSEATFRCRVGGS 136
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCE-IHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P + W + + + + ++ G + I+ A P G Y+ A N G S
Sbjct: 137 PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196
Query: 1368 CILNIEA----YEYVPSVSEEDVLSD---EKTSDVEEFAPRIVKALPT-VVTTTEGKLIR 1419
L +++ P S +L+ + + E AP + T T TEGK R
Sbjct: 197 AALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHAR 256
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L G PKP+ W + G + + + + E +L + Q D G A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 1480 LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEI 1539
+G T + SV +V R+P +VP F K + V E+E
Sbjct: 317 VGQTYS----SVLVVV-----REP-----------------AVP-FKKRLQDLEVREKES 349
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
TF P+ E W+K+ + ++ IE + T++ + D + Y C+
Sbjct: 350 ATF-LCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 69.3 bits (162), Expect = 1e-10
Identities = 71/334 (21%), Positives = 127/334 (38%), Gaps = 14/334 (4%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P+ +T G+ + L C + + + W + + R I + G C
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCS 4955
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I AG Y C SN+FG+ + + + E S L D
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLH 5015
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P V+ E L E A P+ W + E + E L + +
Sbjct: 5016 RLFRTKSPAEVSDEELFLSADEGPAE--PEEPADW-QTYREDEHFICIRFEALTEARQAV 5072
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
T +Q+ +F +GV + + P V E L + L +
Sbjct: 5073 TR---FQE-----MFATLG-IGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLL-TS 5122
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII-ENKENRT 1578
+ P F+ E+ + V + V+F+ + +G P P + W+KD K++ D+ ++I E+++
Sbjct: 5123 DAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I G Y C A + +G++ TKA+L+V
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 64.5 bits (150), Expect = 4e-09
Identities = 65/256 (25%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 6118
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 6119 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 6174
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE H E+L AA++ T+
Sbjct: 6175 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQ------CHREQLVAAVEVTEQETKV 6228
Query: 1526 VKEIIPERVHEEEIVT 1541
K+ + + EE I T
Sbjct: 6229 PKKTV---IIEETITT 6241
Score = 60.5 bits (140), Expect = 6e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 6083 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 6135
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 6136 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 6195
Query: 1369 ILNIEA--YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
L I++ + E +++ + ++ E P+ + +TT
Sbjct: 6196 ELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEETITT 6241
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 52.0 bits (119), Expect = 2e-05
Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
APR + P + GK L + +G P PQV W + + +++ + D
Sbjct: 9 APRFLTR-PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ-DGDLYR 66
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
LT+ ++ D+G+ V A N +G L V++ +AA
Sbjct: 67 LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-------------------EAA--C 105
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE--RFIIENKEN 1576
+ P F+ RV E TF G+P P + W KD + + + R +E
Sbjct: 106 AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I+ A GTY +A + +G A A L V
Sbjct: 166 ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 51.6 bits (118), Expect = 3e-05
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Query: 1273 EQTCIDGDAPLVLAPLENTTVMDGERIS-LNCKILGRPWPKIDWFHNEKLIETARDITIS 1331
E T +G P V+ L + V G R++ K+ G P P++ WF + + + + I ++
Sbjct: 5251 ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT 5310
Query: 1332 RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
+K L + I E +G Y SN G + L + P EE SD
Sbjct: 5311 DKKI-LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG----PDEPEEKPASDVH 5365
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V PR+++ T +G I K G P P V WLR+ E
Sbjct: 5366 EQLV---PPRMLERF-TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAE 5410
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 5992 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 6051
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 6052 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104
Score = 41.5 bits (93), Expect = 0.029
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 1280 DAPLVLA-PLENTTVMDGERISLNCKILGRPWPK-IDWFHNEKLIETARDITISRQKSGL 1337
D P+VL PLE T + + + L+C RP PK + W+ ++ + + +S + +
Sbjct: 2466 DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQ-M 2522
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
E+ I P AG+Y+C A + STE + +EA E + +D + E+
Sbjct: 2523 AELRILRLMPADAGVYRCQAGS--AHSSTE--VTVEAREVTVTGPLQDAEATEE 2572
Score = 40.7 bits (91), Expect = 0.050
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
+ AAL+ T+ F +E+ + E E +T S P + W KD K +R R
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARC 3141
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKA 1597
+ ++ +R I AT G Y C+A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 38.3 bits (85), Expect = 0.27
Identities = 44/196 (22%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
V TTE + + LE + + P VRWL+ G EL I LT+ D
Sbjct: 2175 VVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAI-AAQGACRSLTIYRCEFADQ 2232
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP--------EWVTHMEELQAALKATQS 1521
G V +A++ + A++ V+ T YR+ ++V E +A L+ +
Sbjct: 2233 GVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKEL 2288
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
T V+ + + E+ E S + ++ W+K ++ ++ ++ + +
Sbjct: 2289 PVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347
Query: 1582 IKKATKDLEGTYTCKA 1597
I + E TYTC A
Sbjct: 2348 ISDVHAEDEDTYTCDA 2363
Score = 36.3 bits (80), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 1553 EILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E++WYKD K + + + +E K R +++A K G Y+C+A
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056
Score = 35.9 bits (79), Expect = 1.4
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 13/137 (9%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDGERISLNCKILGRP 1309
VV A + AG V S + + + I + P ++ PLE+ V GE + L C+ L R
Sbjct: 2795 VVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE-LSRA 2853
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC-------TAS---N 1359
+ W + K I ++ + + + + + I+ A + AG Y C TAS
Sbjct: 2854 GTPVHWLKDRKAIRKSQKYDVVCEGT-MAMLVIRGASLKDAGEYTCEVEASKSTASLHVE 2912
Query: 1360 QFGKCSTECILNIEAYE 1376
+ C TE + N++ E
Sbjct: 2913 EKANCFTEELTNLQVEE 2929
Score = 33.5 bits (73), Expect = 7.6
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 1556 WYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
WYKD + + ERF+ E+ R T+ EGTY+C+ D
Sbjct: 830 WYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGED 875
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 104 bits (249), Expect = 4e-21
Identities = 89/355 (25%), Positives = 150/355 (42%), Gaps = 36/355 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP+ L L+N V DG +S +C + G+P P + WF + KL+E I+ + G ++
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI-----------EAYEYVPSVSEEDVLSD 1389
I P G+Y+C A N G ST+ L + +A E S + LS
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 1390 ------EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E T+D E P++V+ L + +L + + K G P P++ W + G L
Sbjct: 5245 REQEGTESTTD-EGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTA 5303
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
S ++ + L + V ++D+G+ N +G + A L V +E KP
Sbjct: 5304 SAHIRMTD-KKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE--KP 5360
Query: 1504 EWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKV- 1562
H E+L P ++ P++V + +TF G P P + W ++
Sbjct: 5361 ASDVH-EQLVP--------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 1563 ----IRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + + + + + + + +GTYTC A + G A+ A L V
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 73.7 bits (173), Expect = 6e-12
Identities = 76/331 (22%), Positives = 129/331 (38%), Gaps = 30/331 (9%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP L + V G+ +L+C+I+G P P++ W +++ + ++ Q L +
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA-QDGDLYRL 67
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
I + +G Y C A N G+ L ++A + E AP
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-----------------EAACAEQAP 110
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ--STEYQIEELDDGTSI 1458
+ PT + EG + G P+P V W + G L + ++EEL + S
Sbjct: 111 HFLLR-PTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEA-SA 168
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK----PEWVTHMEELQA 1514
L + D G A N LG + AAL V+S R + H++ +
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228
Query: 1515 ALKATQSVPTFVKEIIPER--VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII- 1571
A++A + P V E + +G P PE +W KD +++ R ++
Sbjct: 229 AMRA-EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVY 287
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E+ + I + G YTC A + +G
Sbjct: 288 EDAQENFVLKILFCKQSDRGLYTCTASNLVG 318
Score = 69.3 bits (162), Expect = 1e-10
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 39/357 (10%)
Query: 1250 GVVTCRAENFAGSVSTS-GSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N G + G + E C + AP L + V +G + C++ G
Sbjct: 78 GQYVCRARNAIGEAFAAVGLQVDAEAACAE-QAPHFLLRPTSIRVREGSEATFRCRVGGS 136
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCE-IHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P + W + + + + ++ G + I+ A P G Y+ A N G S
Sbjct: 137 PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196
Query: 1368 CILNIEA----YEYVPSVSEEDVLSD---EKTSDVEEFAPRIVKALPT-VVTTTEGKLIR 1419
L +++ P S +L+ + + E AP + T T TEGK R
Sbjct: 197 AALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHAR 256
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L G PKP+ W + G + + + + E +L + Q D G A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 1480 LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEI 1539
+G T + SV +V R+P +VP F K + V E+E
Sbjct: 317 VGQTYS----SVLVVV-----REP-----------------AVP-FKKRLQDLEVREKES 349
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
TF P+ E W+K+ + ++ IE + T++ + D + Y C+
Sbjct: 350 ATF-LCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 69.3 bits (162), Expect = 1e-10
Identities = 71/334 (21%), Positives = 127/334 (38%), Gaps = 14/334 (4%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P+ +T G+ + L C + + + W + + R I + G C
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCS 4955
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I AG Y C SN+FG+ + + + E S L D
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLH 5015
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P V+ E L E A P+ W + E + E L + +
Sbjct: 5016 RLFRTKSPAEVSDEELFLSADEGPAE--PEEPADW-QTYREDEHFICIRFEALTEARQAV 5072
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
T +Q+ +F +GV + + P V E L + L +
Sbjct: 5073 TR---FQE-----MFATLG-IGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLL-TS 5122
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII-ENKENRT 1578
+ P F+ E+ + V + V+F+ + +G P P + W+KD K++ D+ ++I E+++
Sbjct: 5123 DAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I G Y C A + +G++ TKA+L+V
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 64.5 bits (150), Expect = 4e-09
Identities = 65/256 (25%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 6118
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 6119 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 6174
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE H E+L AA++ T+
Sbjct: 6175 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQ------CHREQLVAAVEVTEQETKV 6228
Query: 1526 VKEIIPERVHEEEIVT 1541
K+ + + EE I T
Sbjct: 6229 PKKTV---IIEETITT 6241
Score = 60.5 bits (140), Expect = 6e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 6083 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 6135
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 6136 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 6195
Query: 1369 ILNIEA--YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
L I++ + E +++ + ++ E P+ + +TT
Sbjct: 6196 ELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEETITT 6241
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 52.0 bits (119), Expect = 2e-05
Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
APR + P + GK L + +G P PQV W + + +++ + D
Sbjct: 9 APRFLTR-PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ-DGDLYR 66
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
LT+ ++ D+G+ V A N +G L V++ +AA
Sbjct: 67 LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-------------------EAA--C 105
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE--RFIIENKEN 1576
+ P F+ RV E TF G+P P + W KD + + + R +E
Sbjct: 106 AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I+ A GTY +A + +G A A L V
Sbjct: 166 ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 51.6 bits (118), Expect = 3e-05
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Query: 1273 EQTCIDGDAPLVLAPLENTTVMDGERIS-LNCKILGRPWPKIDWFHNEKLIETARDITIS 1331
E T +G P V+ L + V G R++ K+ G P P++ WF + + + + I ++
Sbjct: 5251 ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT 5310
Query: 1332 RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
+K L + I E +G Y SN G + L + P EE SD
Sbjct: 5311 DKKI-LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG----PDEPEEKPASDVH 5365
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V PR+++ T +G I K G P P V WLR+ E
Sbjct: 5366 EQLV---PPRMLERF-TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAE 5410
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 5992 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 6051
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 6052 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104
Score = 41.5 bits (93), Expect = 0.029
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 1280 DAPLVLA-PLENTTVMDGERISLNCKILGRPWPK-IDWFHNEKLIETARDITISRQKSGL 1337
D P+VL PLE T + + + L+C RP PK + W+ ++ + + +S + +
Sbjct: 2466 DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQ-M 2522
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
E+ I P AG+Y+C A + STE + +EA E + +D + E+
Sbjct: 2523 AELRILRLMPADAGVYRCQAGS--AHSSTE--VTVEAREVTVTGPLQDAEATEE 2572
Score = 40.7 bits (91), Expect = 0.050
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
+ AAL+ T+ F +E+ + E E +T S P + W KD K +R R
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARC 3141
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKA 1597
+ ++ +R I AT G Y C+A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 38.3 bits (85), Expect = 0.27
Identities = 44/196 (22%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
V TTE + + LE + + P VRWL+ G EL I LT+ D
Sbjct: 2175 VVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAI-AAQGACRSLTIYRCEFADQ 2232
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP--------EWVTHMEELQAALKATQS 1521
G V +A++ + A++ V+ T YR+ ++V E +A L+ +
Sbjct: 2233 GVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKEL 2288
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
T V+ + + E+ E S + ++ W+K ++ ++ ++ + +
Sbjct: 2289 PVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347
Query: 1582 IKKATKDLEGTYTCKA 1597
I + E TYTC A
Sbjct: 2348 ISDVHAEDEDTYTCDA 2363
Score = 36.3 bits (80), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 1553 EILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E++WYKD K + + + +E K R +++A K G Y+C+A
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056
Score = 35.9 bits (79), Expect = 1.4
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 13/137 (9%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDGERISLNCKILGRP 1309
VV A + AG V S + + + I + P ++ PLE+ V GE + L C+ L R
Sbjct: 2795 VVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE-LSRA 2853
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC-------TAS---N 1359
+ W + K I ++ + + + + + I+ A + AG Y C TAS
Sbjct: 2854 GTPVHWLKDRKAIRKSQKYDVVCEGT-MAMLVIRGASLKDAGEYTCEVEASKSTASLHVE 2912
Query: 1360 QFGKCSTECILNIEAYE 1376
+ C TE + N++ E
Sbjct: 2913 EKANCFTEELTNLQVEE 2929
Score = 33.5 bits (73), Expect = 7.6
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 1556 WYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
WYKD + + ERF+ E+ R T+ EGTY+C+ D
Sbjct: 830 WYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGED 875
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 104 bits (249), Expect = 4e-21
Identities = 89/355 (25%), Positives = 150/355 (42%), Gaps = 36/355 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP+ L L+N V DG +S +C + G+P P + WF + KL+E I+ + G ++
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI-----------EAYEYVPSVSEEDVLSD 1389
I P G+Y+C A N G ST+ L + +A E S + LS
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 1390 ------EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E T+D E P++V+ L + +L + + K G P P++ W + G L
Sbjct: 5245 REQEGTESTTD-EGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTA 5303
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
S ++ + L + V ++D+G+ N +G + A L V +E KP
Sbjct: 5304 SAHIRMTD-KKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE--KP 5360
Query: 1504 EWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKV- 1562
H E+L P ++ P++V + +TF G P P + W ++
Sbjct: 5361 ASDVH-EQLVP--------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 1563 ----IRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + + + + + + + +GTYTC A + G A+ A L V
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 73.7 bits (173), Expect = 6e-12
Identities = 76/331 (22%), Positives = 129/331 (38%), Gaps = 30/331 (9%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP L + V G+ +L+C+I+G P P++ W +++ + ++ Q L +
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLA-QDGDLYRL 67
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
I + +G Y C A N G+ L ++A + E AP
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-----------------EAACAEQAP 110
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ--STEYQIEELDDGTSI 1458
+ PT + EG + G P+P V W + G L + ++EEL + S
Sbjct: 111 HFLLR-PTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEA-SA 168
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK----PEWVTHMEELQA 1514
L + D G A N LG + AAL V+S R + H++ +
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228
Query: 1515 ALKATQSVPTFVKEIIPER--VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII- 1571
A++A + P V E + +G P PE +W KD +++ R ++
Sbjct: 229 AMRA-EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVY 287
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E+ + I + G YTC A + +G
Sbjct: 288 EDAQENFVLKILFCKQSDRGLYTCTASNLVG 318
Score = 69.3 bits (162), Expect = 1e-10
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 39/357 (10%)
Query: 1250 GVVTCRAENFAGSVSTS-GSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N G + G + E C + AP L + V +G + C++ G
Sbjct: 78 GQYVCRARNAIGEAFAAVGLQVDAEAACAE-QAPHFLLRPTSIRVREGSEATFRCRVGGS 136
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCE-IHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P + W + + + + ++ G + I+ A P G Y+ A N G S
Sbjct: 137 PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196
Query: 1368 CILNIEA----YEYVPSVSEEDVLSD---EKTSDVEEFAPRIVKALPT-VVTTTEGKLIR 1419
L +++ P S +L+ + + E AP + T T TEGK R
Sbjct: 197 AALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHAR 256
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L G PKP+ W + G + + + + E +L + Q D G A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 1480 LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEI 1539
+G T + SV +V R+P +VP F K + V E+E
Sbjct: 317 VGQTYS----SVLVVV-----REP-----------------AVP-FKKRLQDLEVREKES 349
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
TF P+ E W+K+ + ++ IE + T++ + D + Y C+
Sbjct: 350 ATF-LCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 69.3 bits (162), Expect = 1e-10
Identities = 71/334 (21%), Positives = 127/334 (38%), Gaps = 14/334 (4%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P+ +T G+ + L C + + + W + + R I + G C
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCS 4955
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I AG Y C SN+FG+ + + + E S L D
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLH 5015
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P V+ E L E A P+ W + E + E L + +
Sbjct: 5016 RLFRTKSPAEVSDEELFLSADEGPAE--PEEPADW-QTYREDEHFICIRFEALTEARQAV 5072
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
T +Q+ +F +GV + + P V E L + L +
Sbjct: 5073 TR---FQE-----MFATLG-IGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLL-TS 5122
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII-ENKENRT 1578
+ P F+ E+ + V + V+F+ + +G P P + W+KD K++ D+ ++I E+++
Sbjct: 5123 DAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I G Y C A + +G++ TKA+L+V
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 64.5 bits (150), Expect = 4e-09
Identities = 65/256 (25%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 6118
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 6119 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 6174
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE H E+L AA++ T+
Sbjct: 6175 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQ------CHREQLVAAVEVTEQETKV 6228
Query: 1526 VKEIIPERVHEEEIVT 1541
K+ + + EE I T
Sbjct: 6229 PKKTV---IIEETITT 6241
Score = 60.5 bits (140), Expect = 6e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 6083 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 6135
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 6136 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 6195
Query: 1369 ILNIEA--YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
L I++ + E +++ + ++ E P+ + +TT
Sbjct: 6196 ELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEETITT 6241
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 52.0 bits (119), Expect = 2e-05
Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
APR + P + GK L + +G P PQV W + + +++ + D
Sbjct: 9 APRFLTR-PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ-DGDLYR 66
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
LT+ ++ D+G+ V A N +G L V++ +AA
Sbjct: 67 LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-------------------EAA--C 105
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE--RFIIENKEN 1576
+ P F+ RV E TF G+P P + W KD + + + R +E
Sbjct: 106 AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I+ A GTY +A + +G A A L V
Sbjct: 166 ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 51.6 bits (118), Expect = 3e-05
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Query: 1273 EQTCIDGDAPLVLAPLENTTVMDGERIS-LNCKILGRPWPKIDWFHNEKLIETARDITIS 1331
E T +G P V+ L + V G R++ K+ G P P++ WF + + + + I ++
Sbjct: 5251 ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT 5310
Query: 1332 RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
+K L + I E +G Y SN G + L + P EE SD
Sbjct: 5311 DKKI-LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG----PDEPEEKPASDVH 5365
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V PR+++ T +G I K G P P V WLR+ E
Sbjct: 5366 EQLV---PPRMLERF-TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAE 5410
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 5992 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 6051
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 6052 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104
Score = 41.5 bits (93), Expect = 0.029
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 1280 DAPLVLA-PLENTTVMDGERISLNCKILGRPWPK-IDWFHNEKLIETARDITISRQKSGL 1337
D P+VL PLE T + + + L+C RP PK + W+ ++ + + +S + +
Sbjct: 2466 DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQ-M 2522
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
E+ I P AG+Y+C A + STE + +EA E + +D + E+
Sbjct: 2523 AELRILRLMPADAGVYRCQAGS--AHSSTE--VTVEAREVTVTGPLQDAEATEE 2572
Score = 40.7 bits (91), Expect = 0.050
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
+ AAL+ T+ F +E+ + E E +T S P + W KD K +R R
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARC 3141
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKA 1597
+ ++ +R I AT G Y C+A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 38.3 bits (85), Expect = 0.27
Identities = 44/196 (22%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
V TTE + + LE + + P VRWL+ G EL I LT+ D
Sbjct: 2175 VVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAI-AAQGACRSLTIYRCEFADQ 2232
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP--------EWVTHMEELQAALKATQS 1521
G V +A++ + A++ V+ T YR+ ++V E +A L+ +
Sbjct: 2233 GVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKEL 2288
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
T V+ + + E+ E S + ++ W+K ++ ++ ++ + +
Sbjct: 2289 PVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347
Query: 1582 IKKATKDLEGTYTCKA 1597
I + E TYTC A
Sbjct: 2348 ISDVHAEDEDTYTCDA 2363
Score = 36.3 bits (80), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 1553 EILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E++WYKD K + + + +E K R +++A K G Y+C+A
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056
Score = 35.9 bits (79), Expect = 1.4
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 13/137 (9%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDGERISLNCKILGRP 1309
VV A + AG V S + + + I + P ++ PLE+ V GE + L C+ L R
Sbjct: 2795 VVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE-LSRA 2853
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC-------TAS---N 1359
+ W + K I ++ + + + + + I+ A + AG Y C TAS
Sbjct: 2854 GTPVHWLKDRKAIRKSQKYDVVCEGT-MAMLVIRGASLKDAGEYTCEVEASKSTASLHVE 2912
Query: 1360 QFGKCSTECILNIEAYE 1376
+ C TE + N++ E
Sbjct: 2913 EKANCFTEELTNLQVEE 2929
Score = 33.5 bits (73), Expect = 7.6
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 1556 WYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
WYKD + + ERF+ E+ R T+ EGTY+C+ D
Sbjct: 830 WYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGED 875
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 104 bits (249), Expect = 4e-21
Identities = 89/355 (25%), Positives = 150/355 (42%), Gaps = 36/355 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP+ L L+N V DG +S +C + G+P P + WF + KL+E I+ + G ++
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI-----------EAYEYVPSVSEEDVLSD 1389
I P G+Y+C A N G ST+ L + +A E S + LS
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 1390 ------EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E T+D E P++V+ L + +L + + K G P P++ W + G L
Sbjct: 5245 REQEGTESTTD-EGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTA 5303
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
S ++ + L + V ++D+G+ N +G + A L V +E KP
Sbjct: 5304 SAHIRMTD-KKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE--KP 5360
Query: 1504 EWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKV- 1562
H E+L P ++ P++V + +TF G P P + W ++
Sbjct: 5361 ASDVH-EQLVP--------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAER 5411
Query: 1563 ----IRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + + + + + + + +GTYTC A + G A+ A L V
Sbjct: 5412 GVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 73.7 bits (173), Expect = 6e-12
Identities = 76/331 (22%), Positives = 129/331 (38%), Gaps = 30/331 (9%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP L + V G+ +L+C+I+G P P++ W +++ + ++ Q L +
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLA-QDGDLYRL 67
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
I + +G Y C A N G+ L ++A + E AP
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-----------------EAACAEQAP 110
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ--STEYQIEELDDGTSI 1458
+ PT + EG + G P+P V W + G L + ++EEL + S
Sbjct: 111 HFLLR-PTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEA-SA 168
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK----PEWVTHMEELQA 1514
L + D G A N LG + AAL V+S R + H++ +
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228
Query: 1515 ALKATQSVPTFVKEIIPER--VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII- 1571
A++A + P V E + +G P PE +W KD +++ R ++
Sbjct: 229 AMRA-EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVY 287
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E+ + I + G YTC A + +G
Sbjct: 288 EDAQENFVLKILFCKQSDRGLYTCTASNLVG 318
Score = 69.3 bits (162), Expect = 1e-10
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 39/357 (10%)
Query: 1250 GVVTCRAENFAGSVSTS-GSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N G + G + E C + AP L + V +G + C++ G
Sbjct: 78 GQYVCRARNAIGEAFAAVGLQVDAEAACAE-QAPHFLLRPTSIRVREGSEATFRCRVGGS 136
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCE-IHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P + W + + + + ++ G + I+ A P G Y+ A N G S
Sbjct: 137 PRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196
Query: 1368 CILNIEA----YEYVPSVSEEDVLSD---EKTSDVEEFAPRIVKALPT-VVTTTEGKLIR 1419
L +++ P S +L+ + + E AP + T T TEGK R
Sbjct: 197 AALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHAR 256
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L G PKP+ W + G + + + + E +L + Q D G A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316
Query: 1480 LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEI 1539
+G T + SV +V R+P +VP F K + V E+E
Sbjct: 317 VGQTYS----SVLVVV-----REP-----------------AVP-FKKRLQDLEVREKES 349
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
TF P+ E W+K+ + ++ IE + T++ + D + Y C+
Sbjct: 350 ATF-LCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 69.3 bits (162), Expect = 1e-10
Identities = 71/334 (21%), Positives = 127/334 (38%), Gaps = 14/334 (4%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P+ +T G+ + L C + + + W + + R I + G C
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCS 4955
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I AG Y C SN+FG+ + + + E S L D
Sbjct: 4956 LLIAGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLH 5015
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P V+ E L E A P+ W + E + E L + +
Sbjct: 5016 RLFRTKSPAEVSDEELFLSADEGPAE--PEEPADW-QTYREDEHFICIRFEALTEARQAV 5072
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
T +Q+ +F +GV + + P V E L + L +
Sbjct: 5073 TR---FQE-----MFATLG-IGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLL-TS 5122
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII-ENKENRT 1578
+ P F+ E+ + V + V+F+ + +G P P + W+KD K++ D+ ++I E+++
Sbjct: 5123 DAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I G Y C A + +G++ TKA+L+V
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 63.7 bits (148), Expect = 6e-09
Identities = 64/256 (25%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F +++ A P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNKVL-ASP 6118
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 6119 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 6174
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE H E+L AA++ T+
Sbjct: 6175 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQ------CHREQLVAAVEVTEQETKV 6228
Query: 1526 VKEIIPERVHEEEIVT 1541
K+ + + EE I T
Sbjct: 6229 PKKTV---IIEETITT 6241
Score = 59.3 bits (137), Expect = 1e-07
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 6083 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVLASPFVEGEDAQFTCTIEGAP 6135
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 6136 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 6195
Query: 1369 ILNIEA--YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
L I++ + E +++ + ++ E P+ + +TT
Sbjct: 6196 ELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEETITT 6241
Score = 54.8 bits (126), Expect = 3e-06
Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV +++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 6105 QVPPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 52.0 bits (119), Expect = 2e-05
Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
APR + P + GK L + +G P PQV W + + +++ + D
Sbjct: 9 APRFLTR-PKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQ-DGDLYR 66
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
LT+ ++ D+G+ V A N +G L V++ +AA
Sbjct: 67 LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDA-------------------EAA--C 105
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE--RFIIENKEN 1576
+ P F+ RV E TF G+P P + W KD + + + R +E
Sbjct: 106 AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGE 165
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I+ A GTY +A + +G A A L V
Sbjct: 166 ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 51.6 bits (118), Expect = 3e-05
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Query: 1273 EQTCIDGDAPLVLAPLENTTVMDGERIS-LNCKILGRPWPKIDWFHNEKLIETARDITIS 1331
E T +G P V+ L + V G R++ K+ G P P++ WF + + + + I ++
Sbjct: 5251 ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT 5310
Query: 1332 RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
+K L + I E +G Y SN G + L + P EE SD
Sbjct: 5311 DKKI-LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG----PDEPEEKPASDVH 5365
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V PR+++ T +G I K G P P V WLR+ E
Sbjct: 5366 EQLV---PPRMLERF-TPKKVKKGSSITFSVKVEGRPVPTVHWLREEAE 5410
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 5992 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 6051
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 6052 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104
Score = 41.5 bits (93), Expect = 0.029
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 1280 DAPLVLA-PLENTTVMDGERISLNCKILGRPWPK-IDWFHNEKLIETARDITISRQKSGL 1337
D P+VL PLE T + + + L+C RP PK + W+ ++ + + +S + +
Sbjct: 2466 DIPVVLTRPLEPKTGRELQSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQ-M 2522
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
E+ I P AG+Y+C A + STE + +EA E + +D + E+
Sbjct: 2523 AELRILRLMPADAGVYRCQAGS--AHSSTE--VTVEAREVTVTGPLQDAEATEE 2572
Score = 39.9 bits (89), Expect = 0.087
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
+ AAL+ T+ F +E+ + E E +T S P + W KD K +R R
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-MCWTKDGKTLRGSARC 3141
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKA 1597
+ ++ +R I AT G Y C+A
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 38.3 bits (85), Expect = 0.27
Identities = 44/196 (22%), Positives = 80/196 (40%), Gaps = 15/196 (7%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
V TTE + + LE + + P VRWL+ G EL I LT+ D
Sbjct: 2175 VVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAI-AAQGACRSLTIYRCEFADQ 2232
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP--------EWVTHMEELQAALKATQS 1521
G V +A++ + A++ V+ T YR+ ++V E +A L+ +
Sbjct: 2233 GVYVCDAHD----AQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKEL 2288
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
T V+ + + E+ E S + ++ W+K ++ ++ ++ + +
Sbjct: 2289 PVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLI 2347
Query: 1582 IKKATKDLEGTYTCKA 1597
I + E TYTC A
Sbjct: 2348 ISDVHAEDEDTYTCDA 2363
Score = 36.3 bits (80), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 1553 EILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E++WYKD K + + + +E K R +++A K G Y+C+A
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA 1056
Score = 35.9 bits (79), Expect = 1.4
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 13/137 (9%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDGERISLNCKILGRP 1309
VV A + AG V S + + + I + P ++ PLE+ V GE + L C+ L R
Sbjct: 2795 VVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE-LSRA 2853
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC-------TAS---N 1359
+ W + K I ++ + + + + + I+ A + AG Y C TAS
Sbjct: 2854 GTPVHWLKDRKAIRKSQKYDVVCEGT-MAMLVIRGASLKDAGEYTCEVEASKSTASLHVE 2912
Query: 1360 QFGKCSTECILNIEAYE 1376
+ C TE + N++ E
Sbjct: 2913 EKANCFTEELTNLQVEE 2929
Score = 33.5 bits (73), Expect = 7.6
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 1556 WYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
WYKD + + ERF+ E+ R T+ EGTY+C+ D
Sbjct: 830 WYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGED 875
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 103 bits (248), Expect = 5e-21
Identities = 73/230 (31%), Positives = 115/230 (50%), Gaps = 14/230 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP + L++ V++G+ L C + G P P+I W N + I+ AR S ++G+ E+
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAEL 499
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
HI++A PE G Y C A N G+ S C + +E S E +L + + AP
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVS--CSAWVTVHEKKSSRKSEYLL---PVAPSKPTAP 554
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
++ L + + +G + + + G P P+V WL G E+ +S ++ E+ S L
Sbjct: 555 IFLQGL-SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS-LC 612
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSV-ESIVGTQEY--RKPEWVT 1507
+ EV+ +DTG EA+N G T A L+V E GTQ + KP VT
Sbjct: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 6/212 (2%)
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P + EG + E + G P+PQV W R G + + ++ GT L + V++
Sbjct: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA-ALKATQSV--- 1522
+D G+ EA N G L+VE Q + T + A A++ S+
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGE 158
Query: 1523 --PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F ++ V E ++ F +G P P++ W K N ++ R + K
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +D G YTC V+ G A A+L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 74.1 bits (174), Expect = 4e-12
Identities = 65/257 (25%), Positives = 108/257 (42%), Gaps = 35/257 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTC------------IDGDAPLVLAPLENTTVMDGE 1297
G TC AEN G VS S V E+ AP+ L L + VMDG
Sbjct: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
++++ ++ G P P++ W HN I+ + D Q+ + I+E FPE G Y C A
Sbjct: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLCIQEVFPEDTGTYTCEA 628
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
N G+ T+ +L ++ P + P + + P VT + G+
Sbjct: 629 WNSAGEVRTQAVLTVQE----PHDGTQ---------------PWFI-SKPRSVTASLGQS 668
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSILTMPEVYQDDTGEIVFEA 1476
+ + G P P V WLR G L + T +++ + +D L + +V G+
Sbjct: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILL 727
Query: 1477 YNHLGVTATIAALSVES 1493
N +G + +L +++
Sbjct: 728 KNRVGECSCQVSLMLQN 744
Score = 73.7 bits (173), Expect = 6e-12
Identities = 68/263 (25%), Positives = 119/263 (45%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 995 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1047
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A PE G+YKC A N
Sbjct: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKND 1106
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ +S ++E ++G S
Sbjct: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG-SK 1225
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 1226 LTILAARQEHCGCYTLLVENKLG 1248
Score = 72.1 bits (169), Expect = 2e-11
Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 14/218 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
V E AP L EG+ L+ G P P++ WL G Q +Y +
Sbjct: 440 VMEVAPSFSSVLKDCAVI-EGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEA 494
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA 1514
G + L + + +D G A N LG + A ++V + RK E++ + A
Sbjct: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE---KKSSRKSEYLLPV----A 547
Query: 1515 ALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
K T P F++ + +V + VT SGNP PE++W + I+ E F E +
Sbjct: 548 PSKPT--APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + I++ + GTYTC+A + G T+A L V
Sbjct: 606 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
Score = 70.5 bits (165), Expect = 5e-11
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 12/225 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + P N + +G ++ G P P++ W N + I + + G
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV---LSDEKTSDVE 1396
+ I E G Y C A+N G L +E + + + V L D ++
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQPVVSKTLGDRFSASAV 149
Query: 1397 EFAPRIVKALPTV-------VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E P I P V EG++ R K G P+PQV WL+ L S +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E +G +L + V QDD G N G + A LS++ +
Sbjct: 210 SE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 55.2 bits (127), Expect = 2e-06
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 1268 SSIVEEQTCIDGDAPLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR 1326
+S VE + I G+ P A L V +G+ +CKI GRP P++ W ++ +
Sbjct: 146 ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
Query: 1327 DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+++S +K+G+ + I + G+Y C N GK S L+I+ +
Sbjct: 206 RVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 1712 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 1766
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 1767 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1826
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 1827 ELIVETM 1833
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1843
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 1018 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 1075
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 1196 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1255
Query: 1610 LQVFQR 1615
L V +
Sbjct: 1256 LTVVDK 1261
>BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein.
Length = 510
Score = 103 bits (247), Expect = 6e-21
Identities = 96/385 (24%), Positives = 160/385 (41%), Gaps = 45/385 (11%)
Query: 1248 LIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGERISLNCKIL 1306
LI + R E V SG + ++ G AP L++ + +G ++ C++
Sbjct: 95 LISEIEYRLER--SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVA 152
Query: 1307 GRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
G P PKI WF + K I D TI R G C +H + + G Y A+N G+ S
Sbjct: 153 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 212
Query: 1366 TECILNIEA-------------YEYVPSVSEEDVLSDEKTSDVEE--FAPRIVKALPTVV 1410
L ++A + +V S ++ ++E F P ++A P +
Sbjct: 213 CTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA-PGDL 271
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
T EGKL R++ K G+P P + W G + + +++ ++G L + V D G
Sbjct: 272 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 331
Query: 1471 EIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEII 1530
A N G + S+E +V +E KP P F++++
Sbjct: 332 IYTCIATNRAGQN----SFSLELVVAAKEAHKP-------------------PVFIEKLQ 368
Query: 1531 PERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI--RTDERFIIENKENRTTCTIKKATKD 1588
V + V E G P P+I W K+N+ + TD + ++ I+ ATK+
Sbjct: 369 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 428
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQVF 1613
G YT A ++ G+ A+L V+
Sbjct: 429 DAGWYTVSAKNEAGIVSCTARLDVY 453
Score = 63.7 bits (148), Expect = 6e-09
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
++E S+D G+ TC A N AG S S +V + P+ + L+NT V DG
Sbjct: 321 IIEPVTSRDA-GIYTCIATNRAGQNSFSLELVVAAKEA--HKPPVFIEKLQNTGVADGYP 377
Query: 1299 ISLNCKILGRPWPKIDW-FHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L C++LG P P+I W NE L + +++ + G + I+ A E AG Y +A
Sbjct: 378 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 437
Query: 1358 SNQFGKCSTECILNIEAY 1375
N+ G S C ++ Y
Sbjct: 438 KNEAGIVS--CTARLDVY 453
Score = 62.5 bits (145), Expect = 1e-08
Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 24/228 (10%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV +G+ ++CK+ G P P + W + K + + +++G+ + I+ AG
Sbjct: 272 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 331
Query: 1352 IYKCTASNQFGKCSTECILNIEAYE-YVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
IY C A+N+ G+ S L + A E + P V E + + T
Sbjct: 332 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL---QNTG----------------- 371
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDT 1469
+G +RLE + +G+P PQ+ W ++ L ST+ + + + G L + ++D
Sbjct: 372 -VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 430
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQ-EYRKPEWVTHMEELQAAL 1516
G A N G+ + A L V + Q + KP+ V AAL
Sbjct: 431 GWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAAL 478
>AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein.
Length = 1106
Score = 103 bits (247), Expect = 6e-21
Identities = 96/385 (24%), Positives = 160/385 (41%), Gaps = 45/385 (11%)
Query: 1248 LIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGERISLNCKIL 1306
LI + R E V SG + ++ G AP L++ + +G ++ C++
Sbjct: 744 LISEIEYRLER--SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVA 801
Query: 1307 GRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
G P PKI WF + K I D TI R G C +H + + G Y A+N G+ S
Sbjct: 802 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
Query: 1366 TECILNIEA-------------YEYVPSVSEEDVLSDEKTSDVEE--FAPRIVKALPTVV 1410
L ++A + +V S ++ ++E F P ++A P +
Sbjct: 862 CTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA-PGDL 920
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
T EGKL R++ K G+P P + W G + + +++ ++G L + V D G
Sbjct: 921 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 980
Query: 1471 EIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEII 1530
A N G + S+E +V +E KP P F++++
Sbjct: 981 IYTCIATNRAGQN----SFSLELVVAAKEAHKP-------------------PVFIEKLQ 1017
Query: 1531 PERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI--RTDERFIIENKENRTTCTIKKATKD 1588
V + V E G P P+I W K+N+ + TD + ++ I+ ATK+
Sbjct: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 1077
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQVF 1613
G YT A ++ G+ A+L V+
Sbjct: 1078 DAGWYTVSAKNEAGIVSCTARLDVY 1102
Score = 63.7 bits (148), Expect = 6e-09
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
++E S+D G+ TC A N AG S S +V + P+ + L+NT V DG
Sbjct: 970 IIEPVTSRDA-GIYTCIATNRAGQNSFSLELVVAAKEA--HKPPVFIEKLQNTGVADGYP 1026
Query: 1299 ISLNCKILGRPWPKIDW-FHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L C++LG P P+I W NE L + +++ + G + I+ A E AG Y +A
Sbjct: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
Query: 1358 SNQFGKCSTECILNIEAY 1375
N+ G S C ++ Y
Sbjct: 1087 KNEAGIVS--CTARLDVY 1102
Score = 62.9 bits (146), Expect = 1e-08
Identities = 34/103 (33%), Positives = 49/103 (47%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP + L + V +G R+ L C++ G P P++ WF K + DI I + L +
Sbjct: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE 1383
I EAF + G Y C A+N G +T + IE S SE
Sbjct: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
Score = 60.5 bits (140), Expect = 6e-08
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 7/92 (7%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK------- 1334
P+ L+NT V +G+ + L C++ G P ++ WF I+ + D I ++K
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 1335 SGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
+C + I E FPE AGI+ C+A N +G ++
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
Score = 54.0 bits (124), Expect = 5e-06
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
APR ++ L + EG + LE + G P P+VRW +G EL + + QI
Sbjct: 270 APRFIQKLRSQ-EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGT 1497
L + E ++DDTG A N G T A + +E T
Sbjct: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASST 367
Score = 45.6 bits (103), Expect = 0.002
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTT 1579
+ P F++++ + V E V E +GNPTP + W+ + K + T + I + T
Sbjct: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
I +A +D G YTC A + G T A++
Sbjct: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEV 359
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 8/103 (7%)
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
F P K L EG+++ LE + G P QV+W RQG+E+ S +++I + ++
Sbjct: 439 FPPVFTKELQNTAVA-EGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
Query: 1458 -------ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L + E + +D G A N G + A L V S
Sbjct: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
Score = 45.2 bits (102), Expect = 0.002
Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT--- 1579
P F KE+ V E ++V E G P ++ W++ I+ F I K+ R+T
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 1580 ---CT--IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
CT I + + G +TC A +D G A + A+L V
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 103 bits (247), Expect = 6e-21
Identities = 73/230 (31%), Positives = 115/230 (50%), Gaps = 14/230 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP + L++ V++G+ L C + G P P+I W N + I+ AR S ++G+ E+
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAEL 499
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
HI++A PE G Y C A N G+ S C + +E S E +L + + AP
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVS--CSAWVTVHEKKSSRKSEYLL---PVAPSKPTAP 554
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
++ L + + +G + + + G P P+V WL G E+ +S ++ E+ S L
Sbjct: 555 IFLQGL-SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS-LW 612
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSV-ESIVGTQEY--RKPEWVT 1507
+ EV+ +DTG EA+N G T A L+V E GTQ + KP VT
Sbjct: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 6/212 (2%)
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P + EG + E + G P+PQV W R G + + ++ GT L + V++
Sbjct: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA-ALKATQSV--- 1522
+D G+ EA N G L+VE Q + T + A A++ S+
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGE 158
Query: 1523 --PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F ++ V E ++ F +G P P++ W K N ++ R + K
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +D G YTC V+ G A A+L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 74.5 bits (175), Expect = 3e-12
Identities = 65/257 (25%), Positives = 108/257 (42%), Gaps = 35/257 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTC------------IDGDAPLVLAPLENTTVMDGE 1297
G TC AEN G VS S V E+ AP+ L L + VMDG
Sbjct: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
++++ ++ G P P++ W HN I+ + D Q+ + I+E FPE G Y C A
Sbjct: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEA 628
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
N G+ T+ +L ++ P + P + + P VT + G+
Sbjct: 629 WNSAGEVRTQAVLTVQE----PHDGTQ---------------PWFI-SKPRSVTASLGQS 668
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSILTMPEVYQDDTGEIVFEA 1476
+ + G P P V WLR G L + T +++ + +D L + +V G+
Sbjct: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILL 727
Query: 1477 YNHLGVTATIAALSVES 1493
N +G + +L +++
Sbjct: 728 KNRVGECSCQVSLMLQN 744
Score = 71.7 bits (168), Expect = 2e-11
Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 14/218 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
V E AP L EG+ L+ G P P++ WL G Q +Y +
Sbjct: 440 VMEVAPSFSSVLKDCAVI-EGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEA 494
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA 1514
G + L + + +D G A N LG + A ++V + RK E++ + A
Sbjct: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE---KKSSRKSEYLLPV----A 547
Query: 1515 ALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
K T P F++ + +V + VT SGNP PE++W + I+ E F E +
Sbjct: 548 PSKPT--APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + I++ + GTYTC+A + G T+A L V
Sbjct: 606 GTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
Score = 70.5 bits (165), Expect = 5e-11
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 12/225 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + P N + +G ++ G P P++ W N + I + + G
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV---LSDEKTSDVE 1396
+ I E G Y C A+N G L +E + + + V L D ++
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQPVVSKTLGDRFSASAV 149
Query: 1397 EFAPRIVKALPTV-------VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E P I P V EG++ R K G P+PQV WL+ L S +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E +G +L + V QDD G N G + A LS++ +
Sbjct: 210 SE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
Score = 68.9 bits (161), Expect = 2e-10
Identities = 67/263 (25%), Positives = 117/263 (44%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 995 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1047
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A E G+YKC A N
Sbjct: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALLEDRGLYKCVAKND 1106
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ S ++E ++G S
Sbjct: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENG-SK 1225
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 1226 LTILAARQEHCGCYTLLVENKLG 1248
Score = 55.2 bits (127), Expect = 2e-06
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 1268 SSIVEEQTCIDGDAPLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR 1326
+S VE + I G+ P A L V +G+ +CKI GRP P++ W ++ +
Sbjct: 146 ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
Query: 1327 DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+++S +K+G+ + I + G+Y C N GK S L+I+ +
Sbjct: 206 RVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 54.4 bits (125), Expect = 4e-06
Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 1688 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1747
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
I D + YTCKAV+ +G A A+
Sbjct: 1748 ISDVCGDDDAKYTCKAVNSLGEATCTAE 1775
Score = 52.4 bits (120), Expect = 2e-05
Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 1660 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 1714
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 1715 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1774
Query: 1488 ALSVESI 1494
VE++
Sbjct: 1775 EHIVETM 1781
Score = 49.6 bits (113), Expect = 1e-04
Identities = 26/104 (25%), Positives = 45/104 (43%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 1688 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1747
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + +E E EE+
Sbjct: 1748 ISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGEGEEE 1791
Score = 46.0 bits (104), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 1018 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 1075
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 1076 ILSQEGSLCSVSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 1196 QPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1255
Query: 1610 LQVFQR 1615
L V +
Sbjct: 1256 LTVVDK 1261
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 103 bits (247), Expect = 6e-21
Identities = 73/230 (31%), Positives = 115/230 (50%), Gaps = 14/230 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP + L++ V++G+ L C + G P P+I W N + I+ AR S ++G+ E+
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAEL 499
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
HI++A PE G Y C A N G+ S C + +E S E +L + + AP
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVS--CSAWVTVHEKKSSRKSEYLL---PVAPSKPTAP 554
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
++ L + + +G + + + G P P+V WL G E+ +S ++ E+ S L
Sbjct: 555 IFLQGL-SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS-LW 612
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSV-ESIVGTQEY--RKPEWVT 1507
+ EV+ +DTG EA+N G T A L+V E GTQ + KP VT
Sbjct: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
Score = 76.2 bits (179), Expect = 1e-12
Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 6/212 (2%)
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P + EG + E + G P+PQV W R G + + ++ GT L + V++
Sbjct: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA-ALKATQSV--- 1522
+D G+ EA N G L+VE Q + T + A A++ S+
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGE 158
Query: 1523 --PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F ++ V E ++ F +G P P++ W K N ++ R + K
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +D G YTC V+ G A A+L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 74.5 bits (175), Expect = 3e-12
Identities = 65/257 (25%), Positives = 108/257 (42%), Gaps = 35/257 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTC------------IDGDAPLVLAPLENTTVMDGE 1297
G TC AEN G VS S V E+ AP+ L L + VMDG
Sbjct: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
++++ ++ G P P++ W HN I+ + D Q+ + I+E FPE G Y C A
Sbjct: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEA 628
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
N G+ T+ +L ++ P + P + + P VT + G+
Sbjct: 629 WNSAGEVRTQAVLTVQE----PHDGTQ---------------PWFI-SKPRSVTASLGQS 668
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSILTMPEVYQDDTGEIVFEA 1476
+ + G P P V WLR G L + T +++ + +D L + +V G+
Sbjct: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILL 727
Query: 1477 YNHLGVTATIAALSVES 1493
N +G + +L +++
Sbjct: 728 KNRVGECSCQVSLMLQN 744
Score = 73.7 bits (173), Expect = 6e-12
Identities = 68/263 (25%), Positives = 119/263 (45%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 995 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1047
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A PE G+YKC A N
Sbjct: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKND 1106
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ +S ++E ++G S
Sbjct: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG-SK 1225
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 1226 LTILAARQEHCGCYTLLVENKLG 1248
Score = 71.7 bits (168), Expect = 2e-11
Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 14/218 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
V E AP L EG+ L+ G P P++ WL G Q +Y +
Sbjct: 440 VMEVAPSFSSVLKDCAVI-EGQDFVLQCSVRGTPVPRITWLLNG----QPIQYARSTCEA 494
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQA 1514
G + L + + +D G A N LG + A ++V + RK E++ + A
Sbjct: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE---KKSSRKSEYLLPV----A 547
Query: 1515 ALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
K T P F++ + +V + VT SGNP PE++W + I+ E F E +
Sbjct: 548 PSKPT--APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + I++ + GTYTC+A + G T+A L V
Sbjct: 606 GTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
Score = 70.5 bits (165), Expect = 5e-11
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 12/225 (5%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + P N + +G ++ G P P++ W N + I + + G
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV---LSDEKTSDVE 1396
+ I E G Y C A+N G L +E + + + V L D ++
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQPVVSKTLGDRFSASAV 149
Query: 1397 EFAPRIVKALPTV-------VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E P I P V EG++ R K G P+PQV WL+ L S +
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E +G +L + V QDD G N G + A LS++ +
Sbjct: 210 SE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 55.2 bits (127), Expect = 2e-06
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 1268 SSIVEEQTCIDGDAPLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR 1326
+S VE + I G+ P A L V +G+ +CKI GRP P++ W ++ +
Sbjct: 146 ASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
Query: 1327 DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+++S +K+G+ + I + G+Y C N GK S L+I+ +
Sbjct: 206 RVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 1712 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 1766
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 1767 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1826
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 1827 ELIVETM 1833
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1843
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 1018 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 1075
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 1196 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 1255
Query: 1610 LQVFQR 1615
L V +
Sbjct: 1256 LTVVDK 1261
>AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein.
Length = 772
Score = 103 bits (247), Expect = 6e-21
Identities = 96/385 (24%), Positives = 160/385 (41%), Gaps = 45/385 (11%)
Query: 1248 LIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGERISLNCKIL 1306
LI + R E V SG + ++ G AP L++ + +G ++ C++
Sbjct: 357 LISEIEYRLER--SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVA 414
Query: 1307 GRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
G P PKI WF + K I D TI R G C +H + + G Y A+N G+ S
Sbjct: 415 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 474
Query: 1366 TECILNIEA-------------YEYVPSVSEEDVLSDEKTSDVEE--FAPRIVKALPTVV 1410
L ++A + +V S ++ ++E F P ++A P +
Sbjct: 475 CTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA-PGDL 533
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
T EGKL R++ K G+P P + W G + + +++ ++G L + V D G
Sbjct: 534 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 593
Query: 1471 EIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEII 1530
A N G + S+E +V +E KP P F++++
Sbjct: 594 IYTCIATNRAGQN----SFSLELVVAAKEAHKP-------------------PVFIEKLQ 630
Query: 1531 PERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI--RTDERFIIENKENRTTCTIKKATKD 1588
V + V E G P P+I W K+N+ + TD + ++ I+ ATK+
Sbjct: 631 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 690
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQVF 1613
G YT A ++ G+ A+L V+
Sbjct: 691 DAGWYTVSAKNEAGIVSCTARLDVY 715
Score = 63.7 bits (148), Expect = 6e-09
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
++E S+D G+ TC A N AG S S +V + P+ + L+NT V DG
Sbjct: 583 IIEPVTSRDA-GIYTCIATNRAGQNSFSLELVVAAKEA--HKPPVFIEKLQNTGVADGYP 639
Query: 1299 ISLNCKILGRPWPKIDW-FHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L C++LG P P+I W NE L + +++ + G + I+ A E AG Y +A
Sbjct: 640 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 699
Query: 1358 SNQFGKCSTECILNIEAY 1375
N+ G S C ++ Y
Sbjct: 700 KNEAGIVS--CTARLDVY 715
Score = 62.5 bits (145), Expect = 1e-08
Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 24/228 (10%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV +G+ ++CK+ G P P + W + K + + +++G+ + I+ AG
Sbjct: 534 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 593
Query: 1352 IYKCTASNQFGKCSTECILNIEAYE-YVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
IY C A+N+ G+ S L + A E + P V E + + T
Sbjct: 594 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL---QNTG----------------- 633
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDT 1469
+G +RLE + +G+P PQ+ W ++ L ST+ + + + G L + ++D
Sbjct: 634 -VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 692
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQ-EYRKPEWVTHMEELQAAL 1516
G A N G+ + A L V + Q + KP+ V AAL
Sbjct: 693 GWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAAL 740
>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
Length = 1040
Score = 103 bits (246), Expect = 8e-21
Identities = 89/356 (25%), Positives = 150/356 (42%), Gaps = 37/356 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP+ L L+N V DG +S +C + G+P P + WF + KL+E I+ + G ++
Sbjct: 696 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 755
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI-----------EAYEYVPSVSEEDVLS- 1388
I P G+Y+C A N G ST+ L + +A E S + LS
Sbjct: 756 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLST 815
Query: 1389 ------DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELL 1442
E T+D E P++V+ L + +L + + K G P P++ W + G L
Sbjct: 816 SREQEGTESTTD-EGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLT 874
Query: 1443 QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK 1502
S ++ + L + V ++D+G+ N +G + A L V +E K
Sbjct: 875 ASAHIRMTD-KKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE--K 931
Query: 1503 PEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKV 1562
P H E+L P ++ P++V + +TF G P P + W ++
Sbjct: 932 PASDVH-EQLVP--------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAE 982
Query: 1563 -----IRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + + + + + + + +GTYTC A + G A+ A L V
Sbjct: 983 RGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 1038
Score = 69.3 bits (162), Expect = 1e-10
Identities = 71/334 (21%), Positives = 127/334 (38%), Gaps = 14/334 (4%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P+ +T G+ + L C + + + W + + R I + G C
Sbjct: 467 EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCS 526
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I AG Y C SN+FG+ + + + E S L D
Sbjct: 527 LLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLH 586
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P V+ E L E A P+ W + E + E L + +
Sbjct: 587 RLFRTKSPAEVSDEELFLSADEGPAE--PEEPADW-QTYREDEHFICIRFEALTEARQAV 643
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
T +Q+ +F +GV + + P V E L + L +
Sbjct: 644 TR---FQE-----MFATLG-IGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLL-TS 693
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII-ENKENRT 1578
+ P F+ E+ + V + V+F+ + +G P P + W+KD K++ D+ ++I E+++
Sbjct: 694 DAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 753
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I G Y C A + +G++ TKA+L+V
Sbjct: 754 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 787
Score = 55.2 bits (127), Expect = 2e-06
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 10/181 (5%)
Query: 1261 GSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS-LNCKILGRPWPKIDWFHNE 1319
G +STS E T +G P V+ L + V G R++ K+ G P P++ WF +
Sbjct: 811 GYLSTSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 870
Query: 1320 KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVP 1379
+ + + I ++ +K L + I E +G Y SN G + L + P
Sbjct: 871 QPLTASAHIRMTDKKI-LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG----P 925
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
EE SD V PR+++ T +G I K G P P V WLR+
Sbjct: 926 DEPEEKPASDVHEQLV---PPRMLERF-TPKKVKKGSSITFSVKVEGRPVPTVHWLREEA 981
Query: 1440 E 1440
E
Sbjct: 982 E 982
>AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein.
Length = 404
Score = 102 bits (245), Expect = 1e-20
Identities = 89/353 (25%), Positives = 149/353 (42%), Gaps = 42/353 (11%)
Query: 1279 GDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGL 1337
G AP L++ + +G ++ C++ G P PKI WF + K I D TI R G
Sbjct: 19 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 78
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA-------------YEYVPSVSEE 1384
C +H + + G Y A+N G+ S L ++A + +V
Sbjct: 79 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 138
Query: 1385 DVLSDEKTSDVEE--FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELL 1442
S ++ ++E F P ++A P +T EGKL R++ K G+P P + W G +
Sbjct: 139 SRDSGDENEPIQERFFRPHFLQA-PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 197
Query: 1443 QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK 1502
+ +++ ++G L + V D G A N G + S+E +V +E K
Sbjct: 198 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN----SFSLELVVAAKEAHK 253
Query: 1503 PEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKV 1562
P P F++++ V + V E G P P+I W K+N+
Sbjct: 254 P-------------------PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENES 294
Query: 1563 I--RTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ TD + ++ I+ ATK+ G YT A ++ G+ A+L V+
Sbjct: 295 LTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 347
Score = 63.7 bits (148), Expect = 6e-09
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
++E S+D G+ TC A N AG S S +V + P+ + L+NT V DG
Sbjct: 215 IIEPVTSRDA-GIYTCIATNRAGQNSFSLELVVAAKEA--HKPPVFIEKLQNTGVADGYP 271
Query: 1299 ISLNCKILGRPWPKIDW-FHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L C++LG P P+I W NE L + +++ + G + I+ A E AG Y +A
Sbjct: 272 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 331
Query: 1358 SNQFGKCSTECILNIEAY 1375
N+ G S C ++ Y
Sbjct: 332 KNEAGIVS--CTARLDVY 347
Score = 62.5 bits (145), Expect = 1e-08
Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 24/228 (10%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV +G+ ++CK+ G P P + W + K + + +++G+ + I+ AG
Sbjct: 166 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 225
Query: 1352 IYKCTASNQFGKCSTECILNIEAYE-YVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
IY C A+N+ G+ S L + A E + P V E + + T
Sbjct: 226 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL---QNTG----------------- 265
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDT 1469
+G +RLE + +G+P PQ+ W ++ L ST+ + + + G L + ++D
Sbjct: 266 -VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 324
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQ-EYRKPEWVTHMEELQAAL 1516
G A N G+ + A L V + Q + KP+ V AAL
Sbjct: 325 GWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAAL 372
Score = 46.0 bits (104), Expect = 0.001
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
AA T P F ++ ++ E VTF +GNP P+I W+KD K I
Sbjct: 13 AASWKTGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 72
Query: 1574 KENRTTCTI--KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
++ TC++ +T D +G YT A + G +L V
Sbjct: 73 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 113
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 97.9 bits (233), Expect = 3e-19
Identities = 69/235 (29%), Positives = 108/235 (45%), Gaps = 25/235 (10%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P +++ L+N TV++GE ++L C I G P P + W+ + IE++ D I+ Q SG+ +
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-SGIARLM 955
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE-------------------YVPS-- 1380
I+EAF E +G + C+A N+ G ST C L ++ E +V S
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1015
Query: 1381 -VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
V + L++E+ E AP + P V EG + + G PKP V W + G
Sbjct: 1016 VVMTDTSLTEEQAGPGEPAAPYFI-TKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 1440 ELLQSTEYQIE-ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L Y++ G L + + DD GE N G T+ A+L E+
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1129
Score = 91.1 bits (216), Expect = 4e-17
Identities = 72/269 (26%), Positives = 122/269 (45%), Gaps = 17/269 (6%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P VL L+ TV G+ I GRP PKI W+ E+L+ T
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I EAFPE A +Y C A N +G +T L++E VP V D ++ +
Sbjct: 3251 LLI-EAFPEDAAVYTCEAKNDYGVATTSASLSVE----VPEVVSPD-------QEMPVYP 3298
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P I+ L V T+EG+ R + + G +V W + ++ S +++ + +D T L
Sbjct: 3299 PAIITPLQDTV-TSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQL 3355
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYR-KPEWVTHMEELQAALKA 1518
+ E Y +D G F A N +G ++ A LS+E+ R + E M+E ++ +
Sbjct: 3356 EIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLS 3415
Query: 1519 TQSVPTFVKEIIPERVHEE-EIVTFEAIY 1546
+ E+ +++E E+++ +Y
Sbjct: 3416 AEEEGLHSAELQLSKINETLELLSESPVY 3444
Score = 83.0 bits (196), Expect = 9e-15
Identities = 68/244 (27%), Positives = 107/244 (43%), Gaps = 18/244 (7%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E + +SE V + S+ E P +K + + G + L IGIPKP+++W
Sbjct: 3433 ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNA-DISMGDVATLSVTVIGIPKPKIQWF 3491
Query: 1436 RQGTELLQSTEYQ-IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
G L S +Y+ + + DD + I+ ++ +D GE A N G T A L + S
Sbjct: 3492 FNGVLLTPSADYKFVFDGDDHSLIILFTKL--EDEGEYTCMASNDYGKTICSAYLKINS- 3548
Query: 1495 VGTQEYRKPEWVTHMEELQAALKATQSV-----PTFVKEIIPERVHEEEIVTFEAIYSGN 1549
K E E A K+ + + P F+KE+ P R + FE G
Sbjct: 3549 -------KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 3601
Query: 1550 PTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P P + W+K+NK + T + II N T + ++ G Y CKA + +G + A
Sbjct: 3602 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 3661
Query: 1609 KLQV 1612
+L V
Sbjct: 3662 ELLV 3665
Score = 75.4 bits (177), Expect = 2e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 72.9 bits (171), Expect = 1e-11
Identities = 56/217 (25%), Positives = 92/217 (42%), Gaps = 7/217 (3%)
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+G P+ + + N + G+ +L+ ++G P PKI WF N L+ + D
Sbjct: 3453 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3512
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGK--CSTECILNIEAYEYVPSVSEEDVLSD-EKTSD 1394
I + E G Y C ASN +GK CS +N + + + +E V EK
Sbjct: 3513 SLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3571
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
P +K L + +G E +G P P V W ++ +L S Y I +
Sbjct: 3572 --PCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 3628
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
G+ + + ++D+G + +A N LG + A L V
Sbjct: 3629 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 68.1 bits (159), Expect = 3e-10
Identities = 46/161 (28%), Positives = 79/161 (49%), Gaps = 12/161 (7%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGD------APLVLAPLENTTVMDGERISLNCK 1304
V TC A+N G +TS S VE + D P ++ PL++T +G+ C+
Sbjct: 3262 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR 3321
Query: 1305 ILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
+ G K+ W+ +K I+ +R ++ Q ++ I EA+PE G Y A+N G+
Sbjct: 3322 VSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVANNAVGQV 3379
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
S+ L++EA E S+ E + E +++EF+ + A
Sbjct: 3380 SSTANLSLEAPE---SILHERI-EQEIEMEMKEFSSSFLSA 3416
Score = 67.3 bits (157), Expect = 5e-10
Identities = 78/361 (21%), Positives = 139/361 (38%), Gaps = 31/361 (8%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +V L V T EG+ + LE G P P V W R+ ++ S ++QI G + L
Sbjct: 897 PTLVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQIT-FQSGIARL 954
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSV--------ESIVGTQEYRKPE--WVTHM 1509
+ E + +D+G A N G +T L+V E+ T+++ E +V
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1510 EELQAALKATQ--------SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNK 1561
+ + T+ + P F+ + + +++ E V F GNP P + W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 1562 VIRTDERFIIENKENRTTC--TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXX 1619
+ T R+ + + C I D G YT + G A L + +
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADYEL 1133
Query: 1620 XXXXXXXXXXXXXXXXXXEEESVGVEDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSE 1679
+E VG E F + +K+ + ++K+ AK V
Sbjct: 1134 LMKSQQEMLYQTQVTAFVQEPEVG-ETAPGFVYSEYEKEYEKEQAL--IRKKMAKDTVVV 1190
Query: 1680 SEHIETEDIALQKKVDEKTKGIPVEEKAKPILTTHEHVVLSEQQEGESVEPFDESYQTQK 1739
++E ++ + + K E + + I TT E ++ + +E +V+ ES +
Sbjct: 1191 RTYVEDQEFHISSFEERLIK----EIEYRIIKTTLEELLEEDGEEKMAVD-ISESEAVES 1245
Query: 1740 G 1740
G
Sbjct: 1246 G 1246
Score = 65.3 bits (152), Expect = 2e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPNPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 64.9 bits (151), Expect = 3e-09
Identities = 57/215 (26%), Positives = 91/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G P P + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 64.5 bits (150), Expect = 4e-09
Identities = 76/359 (21%), Positives = 131/359 (36%), Gaps = 42/359 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
++N +++G ++ +CK+ G P PKI W+ + K I+ + + G + I P
Sbjct: 1251 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1310
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
E GIY ASN G L +E P + + + E S + +PR V P
Sbjct: 1311 EDEGIYTAFASNIKGNAICSGKLYVE--PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSP 1368
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL-------- 1459
++ R+ + + + G L ++ E Q+E L +L
Sbjct: 1369 IRMSPARMSPARMSPARMSPAR-----MSPGRRLEETDESQLERLYKPVFVLKPVSFKCL 1423
Query: 1460 --------------TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
MPE + G+ + Y H V S+ IV EW
Sbjct: 1424 EGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL-IIVPATPSDSGEW 1482
Query: 1506 VTHMEE----------LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEIL 1555
+ L Q P FV+++ + E + + +GNP P+I+
Sbjct: 1483 TVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIV 1542
Query: 1556 WYKDNKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
W K++ +I + + IE + I YT A++ G T+ K+ V
Sbjct: 1543 WLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Score = 63.7 bits (148), Expect = 6e-09
Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 4/185 (2%)
Query: 1431 QVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALS 1490
QV W +L S +Y+I +DG +IL + ++ + D G + N G ++ A L
Sbjct: 25102 QVTWYFGVRQLENSEKYEIT-YEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELF 25160
Query: 1491 VESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNP 1550
V+ + +Y + ++ ++ + P F + + + E V F + +P
Sbjct: 25161 VKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 25220
Query: 1551 TPEILWYKDNKVIR---TDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
P + WYK + I+ D+++ E+ + TI T D + YT A + G K
Sbjct: 25221 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 25280
Query: 1608 AKLQV 1612
AKL V
Sbjct: 25281 AKLTV 25285
Score = 62.9 bits (146), Expect = 1e-08
Identities = 59/214 (27%), Positives = 94/214 (43%), Gaps = 20/214 (9%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI- 1458
P++++ L V T GK R A G P+P++ W ++ E L ST ++ + L DG
Sbjct: 3193 PQVLQELQPV-TVQSGKPARFCAMISGRPQPKISWYKE--EQLLSTGFKCKFLHDGQEYT 3249
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E + +D EA N GV T A+LSVE PE V+ +E+
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV---------PEVVSPDQEMPVY--- 3297
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P + + E + F+ SG ++ WY +K I+ F + E+
Sbjct: 3298 ---PPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3353
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A + EGTYT A + +G + A L +
Sbjct: 3354 QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSL 3387
Score = 61.3 bits (142), Expect = 3e-08
Identities = 49/203 (24%), Positives = 83/203 (40%), Gaps = 23/203 (11%)
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P ++W H+ K +E A + + + G C + A+ +GI C A+N++G T
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINE-FGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSA 1744
Query: 1369 IL-------------------NIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
L ++ E + ++ E L+ T E+ P IV P
Sbjct: 1745 TLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIV-LYPEP 1803
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
V EG+ R + G P+P+V W G + +S +++ DG L + + DT
Sbjct: 1804 VRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDT 1861
Query: 1470 GEIVFEAYNHLGVTATIAALSVE 1492
GE+ A N GV L ++
Sbjct: 1862 GEVKVTAENPEGVIEHKVKLEIQ 1884
Score = 60.9 bits (141), Expect = 4e-08
Identities = 54/197 (27%), Positives = 88/197 (44%), Gaps = 27/197 (13%)
Query: 1391 KTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
KT AP I K + V TT G+ +L + +G P P ++W R G EL+QS +Y++
Sbjct: 24027 KTKLTSGEAPGIRKEMKDV-TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 24085
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME 1510
D T LT+ Q+D G A N +G T + L +++ T ++ P + E
Sbjct: 24086 S-DGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---TPQFH-PGYPL-KE 24139
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFI 1570
+ A+ +T R+H +Y G P P + W+ K+++ E
Sbjct: 24140 KYYGAVGSTL------------RLH--------VMYIGRPVPAMTWFHGQKLLQNSENIT 24179
Query: 1571 IENKENRTTCTIKKATK 1587
IEN E+ T +K +
Sbjct: 24180 IENTEHYTHLVMKNVQR 24196
Score = 60.5 bits (140), Expect = 6e-08
Identities = 63/232 (27%), Positives = 97/232 (41%), Gaps = 29/232 (12%)
Query: 1381 VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V EE + + + +V A +KA T ++ EG+ + L+A G V+W+ G E
Sbjct: 26524 VHEEITKTSQASEEVRTHAE--IKAFSTQMSINEGQRLVLKANIAGAT--DVKWVLNGVE 26579
Query: 1441 LLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEY 1500
L S EY+ + LT+ + D G + T + + E IV Q Y
Sbjct: 26580 LTNSEEYRYG-VSGSDQTLTIKQASHRDEGIL------------TCISKTKEGIVKCQ-Y 26625
Query: 1501 RKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
+T +EL A P F+ + + ++E + V F SG P+PEI W+K+N
Sbjct: 26626 D----LTLSKELSDA-------PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNN 26674
Query: 1561 KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I I N + I+ A+ G YT KA + G A L V
Sbjct: 26675 LPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 60.1 bits (139), Expect = 8e-08
Identities = 82/356 (23%), Positives = 132/356 (37%), Gaps = 48/356 (13%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
VL P+ + ++G + K++GRP P+ WFH+ + I + ++ G + I
Sbjct: 1414 VLKPV-SFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV 1472
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
A P +G + A N+ G+ S IL +EA E+ + P V
Sbjct: 1473 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH-------------------QVKPMFV 1513
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTSILTMP 1462
+ L V EG + ++ +A G P P + WL+ ++ +I E G + L +
Sbjct: 1514 EKLKN-VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1572
Query: 1463 EVYQDDTGEIVFEAYNHLGVTATIAALSVE-----------SIVGTQEYRKPEWVT---- 1507
D+ A N G T ++VE I+ YR E
Sbjct: 1573 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELE 1632
Query: 1508 --HM-------EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS--GNPTPEILW 1556
H+ EE K Q P F K++ R+ FE + +PT + W
Sbjct: 1633 PLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEW 1692
Query: 1557 YKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D K + R + N+ + A G TC+A + G T A L V
Sbjct: 1693 LHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 59.7 bits (138), Expect = 1e-07
Identities = 32/123 (26%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G++TC ++ G V + ++ DAP ++ + + +G+ + C+I G P
Sbjct: 26608 GILTCISKTKEGIVKCQYDLTLSKEL---SDAPAFISQPRSQNINEGQNVLFTCEISGEP 26664
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I+WF N I + +++ISR ++ + + I+ A +G Y A N G+CS
Sbjct: 26665 SPEIEWFKNNLPISISSNVSISRSRN-VYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 26723
Query: 1370 LNI 1372
L +
Sbjct: 26724 LMV 26726
Score = 58.8 bits (136), Expect = 2e-07
Identities = 70/326 (21%), Positives = 127/326 (38%), Gaps = 24/326 (7%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + L + KL + ++ + +V W + G +L ++ +Q DGT L
Sbjct: 26221 PKITQFLKAEASKEIAKLTCVVESSV-LRAKEVTWYKDGKKLKENGHFQFHYSADGTYEL 26279
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATI------AALSV-ESIVGTQEYRKPEW------V 1506
+ + + D GE V E G + T A S+ E + E +K + V
Sbjct: 26280 KINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTV 26339
Query: 1507 THMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD 1566
T E +A + S P V + V + + F +G P P +W KD K I
Sbjct: 26340 TRKTEPKAP-EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 26398
Query: 1567 ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXXXXXXXXX 1626
++ + + I K G YTC + G + KL +
Sbjct: 26399 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI----KAIKDTEAQK 26454
Query: 1627 XXXXXXXXXXXEEESVGVEDTLDFATVSEVQALDKQHSTDK--VKKRKAKIVVSESEHIE 1684
++++V E+ A SE + + S +K +K+ +K+++SE E +
Sbjct: 26455 VSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKK 26513
Query: 1685 TEDIALQKKV--DEKTKGIPVEEKAK 1708
+ +L+K + +E TK E+ +
Sbjct: 26514 SAATSLEKSIVHEEITKTSQASEEVR 26539
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 55.6 bits (128), Expect = 2e-06
Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
P+ Y+ + G E +GV+ T + E + + VT + A ++ +
Sbjct: 841 PDTYKSEAG---VEVKKEVGVSITGTTVREERFEVL--HGREAKVTETARVPAPVEIPVT 895
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT V + V E E VT E SG P+P + WY+++ I + F I +
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++A + G +TC AV++ G T L V
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 55.6 bits (128), Expect = 2e-06
Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 27/239 (11%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDW 1315
AEN G +++ + G+AP + +++ T GE L+C+I+GRP P I W
Sbjct: 24010 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 24069
Query: 1316 FH-NEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
+ ++LI++ + S ++ + +E E G+Y C A+N+ G+ T L ++A
Sbjct: 24070 YRFGKELIQSRKYKMSSDGRTHTLTVMTEE--QEDEGVYTCIATNEVGEVETSSKLLLQA 24127
Query: 1375 YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRW 1434
P L ++ V G +RL IG P P + W
Sbjct: 24128 ---TPQFHPGYPLKEKYYGAV-------------------GSTLRLHVMYIGRPVPAMTW 24165
Query: 1435 LRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
G +LLQ++E IE + T ++ + G+ + N G I + ++
Sbjct: 24166 F-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24223
Score = 55.6 bits (128), Expect = 2e-06
Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
GV TC A N G V TS +++ PL E G + L+ +GRP
Sbjct: 24104 GVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK----EKYYGAVGSTLRLHVMYIGRP 24159
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + WFH +KL++ + +ITI + + AG YK SN FG + + I
Sbjct: 24160 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAI 24217
Query: 1370 LNIE 1373
L++E
Sbjct: 24218 LDVE 24221
Score = 54.8 bits (126), Expect = 3e-06
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 1553 EILWYKDNKVIRTDERFIIENKENRTTCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQ 1611
E+ WY +NK++ +DE+F +N T I K T+D +G Y C+A++D G T AKL
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4330
Query: 1612 VFQR 1615
V +R
Sbjct: 4331 VVKR 4334
Score = 53.6 bits (123), Expect = 7e-06
Identities = 75/338 (22%), Positives = 135/338 (39%), Gaps = 20/338 (5%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
+VL P E V++GE C++ G P PK++W+ N +LI ++ + + G+ + I
Sbjct: 1797 IVLYP-EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLDI 1853
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR- 1401
+ G K TA N G + L I+ E SV + E + P
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRR---APEPRPEFHVHEPGK 1910
Query: 1402 ---IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE-LDDGTS 1457
V+ + V TTE K + +A I +V + EL + + EE + +
Sbjct: 1911 LQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVP--EESEELRSKFKRRTEEGYYEAIT 1968
Query: 1458 ILTMPEVYQDDTGEIVFEAYNH--LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ + +D++ E + L T + +++ + P + EL +
Sbjct: 1969 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2028
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN-KVIRTDERFIIENK 1574
++A P + I + V + F G P PE WYK+ K+ R+D + +
Sbjct: 2029 MEA----PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2084
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+N I+ T + + KA++ G + A L V
Sbjct: 2085 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2122
Score = 52.4 bits (120), Expect = 2e-05
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMD---GERISLNCKILGRPWP 1311
A N GS+S S +V TCID P++ PLE T V+ G + L I G+P P
Sbjct: 20347 ARNAVGSISNP-SEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAP 20405
Query: 1312 KIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
I+W+ ++K ++T + + + L I IK+A +G Y+ N S
Sbjct: 20406 TIEWYKDDKELQTNALVCV-ENTTDLASILIKDADRLNSGCYELKLRNAMASAS 20458
Score = 52.4 bits (120), Expect = 2e-05
Identities = 56/243 (23%), Positives = 96/243 (39%), Gaps = 24/243 (9%)
Query: 1255 RAENFAGSVSTSG-SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKI 1313
+ EN G S S + ++ + AP L N V +L CK+ G P P +
Sbjct: 24403 KCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIV 24462
Query: 1314 DWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
W+ K +I I K G ++ I + A +Y+ A+NQ G S L +
Sbjct: 24463 KWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
E VP+ + P+ ++ + V G+++ ++ G P P +
Sbjct: 24523 E----VPA---------------KIHLPKTLEGM-GAVHALRGEVVSIKIPFSGKPDPVI 24562
Query: 1433 RWLRQGTELLQST-EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W ++G +L+ + YQ+ TS++ V + D G V A N G+ L V
Sbjct: 24563 TW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Query: 1492 ESI 1494
+
Sbjct: 24622 ADV 24624
Score = 52.0 bits (119), Expect = 2e-05
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 7/115 (6%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG-LCEI 1340
P+++ L++TTV K G P P W + K I +S K G EI
Sbjct: 26355 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI 26414
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
H + +G+Y CT N G S+ C L I+A + +E +S +KTS++
Sbjct: 26415 HKTDT--SDSGLYTCTVKNSAGSVSSSCKLTIKAIK----DTEAQKVSTQKTSEI 26463
Score = 51.6 bits (118), Expect = 3e-05
Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 5/109 (4%)
Query: 1510 EELQAALKATQSVPTF---VKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD 1566
EE+QA TQ P VK + V + A +G P P+I W K + +++ D
Sbjct: 7180 EEIQAV--DTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQD 7237
Query: 1567 ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+R IEN ++T TI + + GTY +AV+ G A ++ V +
Sbjct: 7238 KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286
Score = 50.8 bits (116), Expect = 5e-05
Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + +++ TV G +++G+P P+ +W+ N IE + I + +CE
Sbjct: 2030 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE-EDVLSDEK 1391
+ I++ E + A N G+ S+ L ++A + + E +DV++ EK
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEK 2142
Score = 50.8 bits (116), Expect = 5e-05
Identities = 65/278 (23%), Positives = 112/278 (40%), Gaps = 35/278 (12%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA---RDITISRQKSGLC 1338
P PL N T GE + I P P + W+ + + I+ + T K GL
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I + Y A N++G+ S + L + + P ++ +
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH---PPPTDSTLRP---------- 25298
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS- 1457
+ K L EG+ + E + GIP P ++W + G L S IE + +G
Sbjct: 25299 ---MFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPL--SLGPNIEIIHEGLDY 25353
Query: 1458 -ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI-VGTQEYR-KPEWVTHMEE--- 1511
L + + +DTG A N G T+ A L VE + QE++ K E H+++
Sbjct: 25354 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQID 25413
Query: 1512 ----LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAI 1545
+ L T+SVP + ++ E + E ++ A+
Sbjct: 25414 KTLRMAEILSGTESVP--LTQVAKEALREAAVLYKPAV 25449
Score = 49.6 bits (113), Expect = 1e-04
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 1510 EELQAALKATQSVPT-FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER 1568
E++ + +++V + F I R+ E VTF SG P P+I WYKD K I+ ER
Sbjct: 1231 EKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1290
Query: 1569 FIIE-NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ ++ R + I + EG YT A + G A+ KL V
Sbjct: 1291 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1335
Score = 49.6 bits (113), Expect = 1e-04
Identities = 41/153 (26%), Positives = 66/153 (43%), Gaps = 8/153 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLENTTVMDGERISLNCKILGR 1308
G T A+N AG S S VE ++ P+ + L+N + +G R+ + + G
Sbjct: 1480 GEWTVVAQNRAGRSSISVILTVE---AVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGN 1536
Query: 1309 PWPKIDWFHNEKLIETAR--DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P P I W N +I + I I K G + I + + Y TA N+ G+ +T
Sbjct: 1537 PNPDIVWLKNSDIIVPHKYPKIRIEGTK-GEAALKIDSTVSQDSAWYTATAINKAGRDTT 1595
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
C +N+E E+ E ++ T +E A
Sbjct: 1596 RCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIA 1627
Score = 49.6 bits (113), Expect = 1e-04
Identities = 43/113 (38%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDG-DAP-LVLAPL--ENTTVMDGERISLNC-KILGRP 1309
RA+N AG++S S E C D +AP +VL P + T+ G+ I LN ILG+P
Sbjct: 13852 RAKNTAGAISAPSES-TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKP 13910
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
PK W K I + DIT + IK A + AG Y TA+N FG
Sbjct: 13911 LPKSSWSKAGKDIRPS-DITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/70 (31%), Positives = 35/70 (50%)
Query: 1546 YSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAV 1605
+ G PTP + W+KDN ++ R E+ EN + TIK A ++ G Y K + G A+
Sbjct: 15674 FIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAI 15733
Query: 1606 TKAKLQVFQR 1615
+ V +
Sbjct: 15734 ETLNVIVLDK 15743
Score = 46.8 bits (106), Expect = 8e-04
Identities = 23/75 (30%), Positives = 37/75 (49%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E + +A+ G P P + W+KD I I N T+ ++ AT+D G YT +A
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEA 21536
Query: 1598 VSDIGLAVTKAKLQV 1612
+ G A + K++V
Sbjct: 21537 KNASGSAKAEIKVKV 21551
Score = 46.4 bits (105), Expect = 0.001
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++E IG P+P + W++ G L Q+T +EE T +L + E +DD G+
Sbjct: 17829 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST-VLHIKEGNKDDFGKYTV 17887
Query: 1475 EAYNHLGVTAT 1485
A N G TAT
Sbjct: 17888 TATNSAG-TAT 17897
Score = 46.0 bits (104), Expect = 0.001
Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 5/151 (3%)
Query: 1263 VSTSGSSIVEEQTCI-DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
V + +S+ EEQ + AP + +++G + C++ G P P + W +
Sbjct: 1016 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1075
Query: 1322 IETARDITISRQK-SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA-YEYVP 1379
+ T +S K +G C++ I F + AG Y N+ G+ S L EA YE +
Sbjct: 1076 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1135
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
+E + + T+ V+E P + + P V
Sbjct: 1136 KSQQEMLYQTQVTAFVQE--PEVGETAPGFV 1164
Score = 46.0 bits (104), Expect = 0.001
Identities = 57/206 (27%), Positives = 83/206 (40%), Gaps = 17/206 (8%)
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
I P V WL G L + ++ + G L Y D+G I A N G
Sbjct: 1683 ISDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1741
Query: 1485 TIAALSVESIVG-TQEYRKPEW---VTHMEELQ--AALKATQSVPTFVKE-------IIP 1531
T A L V+ +E + PE + +EEL+ A A V T KE + P
Sbjct: 1742 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1801
Query: 1532 E--RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
E RV E E F +G P P++ WY + ++IR +RF + + + D
Sbjct: 1802 EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYD- 1860
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQVFQR 1615
G A + G+ K KL++ QR
Sbjct: 1861 TGEVKVTAENPEGVIEHKVKLEIQQR 1886
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV-----KALPTVVTTTEGKLIRLEAKAIGI 1427
E Y + S E +SD + V A +V K L T G+ ++++ IG
Sbjct: 15618 EEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGR 15677
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
P P V W + L Q+T E ++ S+LT+ + ++D G V + N G
Sbjct: 15678 PTPAVTWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAG 15730
Score = 45.6 bits (103), Expect = 0.002
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQK----SGLCEIHIKEAFP 1347
V GE + + + G P PKI+W NE +IE D + I++++ E+ I +A
Sbjct: 8913 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 8972
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
E G Y TASN+ G +++E Y+ PS ++D K
Sbjct: 8973 EDKGTYTVTASNRLGSVFRN--VHVEVYDR-PSPPRNLAVTDIK 9013
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 8/105 (7%)
Query: 1506 VTHMEELQAA----LKA-TQSVPTFVKEIIPE-RVHEEEIVTFEAIYSGNPTPEILWYKD 1559
+++M +L+++ LKA + +P ++ + + + E +++T ++G PTPE+ W
Sbjct: 26809 ISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG 26868
Query: 1560 NKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ I + E RF IEN ++ TT I K G YT ++ G
Sbjct: 26869 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL--LQSTEYQIEELDDGTS 1457
P ++ALP+ ++ EGK++ + G P P+V W G ++ + + IE DD T+
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 26890
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
++ M +V + D G N G + + + SI
Sbjct: 26891 LIIM-DVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 44.8 bits (101), Expect = 0.003
Identities = 50/215 (23%), Positives = 92/215 (42%), Gaps = 30/215 (13%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
AP+I + + + T +G + +G P P+ W + G ++ +S +D
Sbjct: 2031 APKIFERIQSQ-TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + +V +D+ I+ +A N G T++ A L V++ + +T +ELQ +
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA---------KQLITFTQELQDVV-- 2138
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
KE ++ + TFE + P ++ WYKD + +++ + +
Sbjct: 2139 -------AKE-------KDTMATFEC-ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVH 2183
Query: 1579 TCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+I T D E Y+C V D + T AKL V
Sbjct: 2184 FLSILTIDTSDAE-DYSCVLVEDENVKTT-AKLIV 2216
Score = 44.8 bits (101), Expect = 0.003
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G +R A G+P P +W G+E+ Y + E D+ +S+LT+ + DTGE
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV-ETDNFSSVLTIKNCLRRDTGEYQI 11086
Query: 1475 EAYNHLGVTATIAALSVESIVG 1496
N G L+V + G
Sbjct: 11087 TVSNAAGSKTVAVHLTVLDVPG 11108
Score = 44.8 bits (101), Expect = 0.003
Identities = 23/76 (30%), Positives = 37/76 (48%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V A SG P P I WYKD+K ++T+ +EN + + IK A + G Y K +
Sbjct: 20393 VKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 20452
Query: 1600 DIGLAVTKAKLQVFQR 1615
+ A ++Q+ +
Sbjct: 20453 AMASASATIRVQILDK 20468
Score = 44.8 bits (101), Expect = 0.003
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Query: 1405 ALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEV 1464
AL T V G+ +++ G P P V W + L Y IE D +S+LT+P+V
Sbjct: 20779 ALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS-SSLLTIPQV 20837
Query: 1465 YQDDTGEIVFEAYNHLG 1481
++DTG+ + N +G
Sbjct: 20838 TRNDTGKYILTIENGVG 20854
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/63 (30%), Positives = 33/63 (52%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+I WY+ K + ++ + + T T+ ++ EG YTC A +++G T
Sbjct: 24061 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 24120
Query: 1608 AKL 1610
+KL
Sbjct: 24121 SKL 24123
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I+ +P +T GK +R+EA G P P +W + E++ S+ + + D +SIL
Sbjct: 12403 PKIL--MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKA-DSSSIL 12459
Query: 1460 TMPEVYQDDTGEIVFEAYNHLG 1481
+ +V + D+G A N G
Sbjct: 12460 IIKDVTRKDSGYYSLTAENSSG 12481
Score = 44.0 bits (99), Expect = 0.005
Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 6/134 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
V+++ ++D G C A N +G +TS V ++ AP++ +E V G
Sbjct: 4299 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA-----APVIKRKIEPLEVALGHL 4353
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
C+I P + WF + I + +I R + + I G Y C AS
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 4412
Query: 1359 NQFGKCSTECILNI 1372
N++G S L +
Sbjct: 4413 NEYGSVSCTATLTV 4426
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+V G I++E +G PKP V W ++G ++L+ T+ E ++IL + E + D
Sbjct: 14577 LVIAKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSD 14635
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVG 1496
+G A N +G + + V I G
Sbjct: 14636 SGPYPLTARNIVGEVGDVITIQVHDIPG 14663
Score = 44.0 bits (99), Expect = 0.005
Identities = 18/57 (31%), Positives = 31/57 (54%)
Query: 1546 YSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ G P P + W KD K + +D R+ IEN ++ + TI + T++ G Y + +G
Sbjct: 20798 FKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854
Score = 43.6 bits (98), Expect = 0.007
Identities = 48/226 (21%), Positives = 85/226 (37%), Gaps = 26/226 (11%)
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I D P++ PL +T +G+ + L I +++W+ KL+ + + ++
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA--KEVNWYFENKLVPSDEKFKCLQDQNT 4295
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ K + G Y C A N GK +T L + V+
Sbjct: 4296 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV----------------------VK 4333
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
AP ++K + G L + + P + +W + G E+ +S + I
Sbjct: 4334 RAAP-VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS-SKYI 4391
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK 1502
S L + D GE +A N G + A L+V G ++ RK
Sbjct: 4392 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRK 4437
Score = 43.2 bits (97), Expect = 0.009
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTC---K 1596
V E Y G P P I W KD ++ E EN+ T +IK A K+ G YT
Sbjct: 21084 VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN 21143
Query: 1597 AVSDIGLAVT 1606
AV I + +T
Sbjct: 21144 AVCRIAVPIT 21153
Score = 42.7 bits (96), Expect = 0.012
Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Query: 1232 QPLKALNV-LEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLE 1289
+P+K L +EE + D V+ RA N G + S I E D D P +
Sbjct: 7840 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV--SEPSEISENVVAKDPDCKPTIDLETH 7897
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
+ V++GE++S+ P P + W + K ++ + +T+ + + ++
Sbjct: 7898 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS-AHLEVPKSVRAD 7956
Query: 1350 AGIYKCTASNQFGKCS 1365
AGIY T N+ G +
Sbjct: 7957 AGIYTITLENKLGSAT 7972
Score = 42.7 bits (96), Expect = 0.012
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 9/131 (6%)
Query: 1368 CILNIEAYEYVPSVSEEDVLSD-EKTSDV---EEFA-PRIVKALPTVVTTTEGKLIRLEA 1422
C+ N + YE+ E SD KT +V E+ P + L V+T G IRLEA
Sbjct: 11668 CVEN-QIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEA 11726
Query: 1423 KAIGIPKPQVRWL--RQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHL 1480
G P P+V W + T+L +S +I+ D +S ++ + + D G+ V A N
Sbjct: 11727 GVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD-SSKFSLTKAKRSDGGKYVVTATNTA 11785
Query: 1481 GVTATIAALSV 1491
G A ++V
Sbjct: 11786 GSFVAYATVNV 11796
Score = 42.7 bits (96), Expect = 0.012
Identities = 21/68 (30%), Positives = 30/68 (44%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P I W KD + ++ R +E T IK+ KD G YT A + G A
Sbjct: 17840 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATEN 17899
Query: 1608 AKLQVFQR 1615
+ V ++
Sbjct: 17900 LSVIVLEK 17907
Score = 42.7 bits (96), Expect = 0.012
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLV-LAP--LENTTVMDGERISLNCKILGRPWPK 1312
A N G++S S T + P+V P + + GE + + + GRP P+
Sbjct: 21433 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21492
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ WF + IE ++ I+ G + +++A + G+Y A N G E + +
Sbjct: 21493 VTWFKDGVEIEKRMNMEIT-NVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Query: 1373 E 1373
+
Sbjct: 21552 Q 21552
Score = 42.3 bits (95), Expect = 0.016
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV G + L+ + G+P P + W + L++ A I ++ Q++ LC + + + +G
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDSG 12867
Query: 1352 IYKCTASNQFGKCSTECILNI 1372
Y TA N G S L +
Sbjct: 12868 DYTITAENSSGSKSATIKLKV 12888
Score = 41.9 bits (94), Expect = 0.022
Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++E G PKP + W + G L Q+T + + D T+ L++ E ++DD G+
Sbjct: 16747 GQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT-LSIKETHKDDGGQYGI 16805
Query: 1475 EAYNHLG-VTATIAALSVE 1492
N +G TA+I ++++
Sbjct: 16806 TVANVVGQKTASIEIVTLD 16824
Score = 41.9 bits (94), Expect = 0.022
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + P ++ GE + + ++GRP P I W + + ++ + + + +H
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LH 17873
Query: 1342 IKEAFPEMAGIYKCTASNQFG 1362
IKE + G Y TA+N G
Sbjct: 17874 IKEGNKDDFGKYTVTATNSAG 17894
Score = 41.5 bits (93), Expect = 0.029
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
V+ G+++++ A G P P + W + G E+ + +I D+ T +LT+ + + D
Sbjct: 19301 VIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT-LLTVKDCIRRD 19359
Query: 1469 TGEIVFEAYNHLGVTATIA 1487
TG+ V N G T ++A
Sbjct: 19360 TGQYVLTLKNVAG-TRSVA 19377
Score = 41.1 bits (92), Expect = 0.038
Identities = 40/173 (23%), Positives = 75/173 (43%), Gaps = 11/173 (6%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSS--IVEEQTCIDGDAPLVLAPL 1288
I +K L + N+++ A N AG + S IV+EQT + L L +
Sbjct: 14517 ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP---ELDLRGI 14573
Query: 1289 ENTTVMD--GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
V+ G+ I + +LGRP P + W +++++ + + + ++I E
Sbjct: 14574 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECV 14632
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+G Y TA N G+ ++ I+ ++ +P + DE +SD F+
Sbjct: 14633 RSDSGPYPLTARNIVGEVGD--VITIQVHD-IPGPPTGPIKFDEVSSDFVTFS 14682
Score = 41.1 bits (92), Expect = 0.038
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGT 1592
VH E EA G P P+++W KD K + T R I++ +TT +K + G
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 1593 YTCKAVSDIG 1602
Y K +S++G
Sbjct: 18282 YILK-LSNVG 18290
Score = 41.1 bits (92), Expect = 0.038
Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
EY S++E + + + D+E + L VT G +RL G P P + W
Sbjct: 22930 EYSESIAEIEPVERIEIPDLE-----LADDLKKTVTIRAGASLRLMVSVSGRPPPVITWS 22984
Query: 1436 RQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIV 1495
+QG +L I + + S+L + +V + D G+ EA N G + + V
Sbjct: 22985 KQGIDLASRA---IIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTP 23041
Query: 1496 G 1496
G
Sbjct: 23042 G 23042
Score = 40.3 bits (90), Expect = 0.066
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR--TDERFI----IENKENRTTCTIKKAT 1586
+V E V A +G P P+I W K+ VI TD I + E +T +I KA
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
++ +GTYT A + +G ++V+ R
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDR 9000
Score = 40.3 bits (90), Expect = 0.066
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 1379 PSVSEEDVLS-DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
PS S +++ DE + EF P L G+ +R++A G P P+V W +
Sbjct: 21443 PSQSSGIIMTRDENVPPIVEFGPEYFDGL----IIKSGESLRIKALVQGRPVPRVTWFKD 21498
Query: 1438 GTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
G E+ + +I + TS L + + +D G EA N G + V+ G
Sbjct: 21499 GVEIEKRMNMEITNVLGSTS-LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556
Score = 39.9 bits (89), Expect = 0.087
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 1513 QAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE 1572
+A L + P F ++ E++ V + S P + W+KD K I+ + +I+
Sbjct: 5511 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIK 5569
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ +KKA K G YTC D G T KL + R
Sbjct: 5570 TDGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 5608
Score = 39.9 bits (89), Expect = 0.087
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T G I L A G P+P++ W + L Q IE + S +T+ + + DT
Sbjct: 7203 LTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK-KSTVTIVDSKRSDT 7261
Query: 1470 GEIVFEAYNHLGVTATIAALSV 1491
G + EA N G + ++V
Sbjct: 7262 GTYIIEAVNVCGRATAVVEVNV 7283
Score = 39.9 bits (89), Expect = 0.087
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G+ RLEA G P P + WLR E+ +S +I+ D ++L + + + D
Sbjct: 17138 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN-TDFKALLIVKDAIRIDG 17196
Query: 1470 GEIVFEAYNHLG 1481
G+ + A N G
Sbjct: 17197 GQYILRASNVAG 17208
Score = 39.9 bits (89), Expect = 0.087
Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 2/120 (1%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
+++ D V RA N GSVS + S VE I P L + + GE +S+
Sbjct: 24494 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH--LPKTLEGMGAVHALRGEVVSIK 24551
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
G+P P I W + LI+ + +S + + AG Y A N+FG
Sbjct: 24552 IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24611
Score = 39.5 bits (88), Expect = 0.12
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRI--VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
++S SD T E PRI A+ +++T G + L+A G P P V W +
Sbjct: 12776 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 12835
Query: 1438 GTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
GT LL+ E + L + V + D+G+ A N G + L V
Sbjct: 12836 GT-LLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 12888
Score = 39.5 bits (88), Expect = 0.12
Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
T + G P P +LW K + +RT R ++ ++RT+ TI+ A ++ G YT
Sbjct: 19708 TMTVPFRGRPVPNVLWSKPDTDLRT--RAYVDTTDSRTSLTIENANRNDSGKYT 19759
Score = 39.1 bits (87), Expect = 0.15
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 1544 AIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGL 1603
A+ +G P P +W K+ + D R +I+N ++ IK A + G Y A + G
Sbjct: 8629 AVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGS 8687
Query: 1604 AVTKAKLQVF 1613
A+++VF
Sbjct: 8688 KFAAARVEVF 8697
Score = 39.1 bits (87), Expect = 0.15
Identities = 22/73 (30%), Positives = 28/73 (38%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V F AI G P P W D I+TDE + +E + TIK + G Y +
Sbjct: 11031 VRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSN 11090
Query: 1600 DIGLAVTKAKLQV 1612
G L V
Sbjct: 11091 AAGSKTVAVHLTV 11103
Score = 39.1 bits (87), Expect = 0.15
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTMPEVYQD 1467
V+T G+ IR+ A+ G P+P + W ++G L++ E +++ + D + L + E +
Sbjct: 11420 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR--EKRVDLIQDLPRVELQIKEAVRA 11477
Query: 1468 DTGEIVFEAYNHLGVTATIAALSV 1491
D G+ + A N G A ++V
Sbjct: 11478 DHGKYIISAKNSSGHAQGSAIVNV 11501
Score = 39.1 bits (87), Expect = 0.15
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV G+ I + ++ GRP P I W K++ + + + Q E+ IKEA G
Sbjct: 11422 TVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI-QDLPRVELQIKEAVRADHG 11480
Query: 1352 IYKCTASNQFGKCSTECILNI 1372
Y +A N G I+N+
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV 11501
Score = 39.1 bits (87), Expect = 0.15
Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRI---VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLR 1436
++S SD T + AP+I VK TV+ G+ RLEA G P P + W +
Sbjct: 14942 AISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKA-GEAFRLEADVSGRPPPTMEWSK 15000
Query: 1437 QGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
G EL + + +I+ D T+++ + D+G A N G I + V G
Sbjct: 15001 DGKELEGTAKLEIKIADFSTNLVNKDST-RRDSGAYTLTATNPGGFAKHIFNVKVLDRPG 15059
Query: 1497 TQE 1499
E
Sbjct: 15060 PPE 15062
Score = 39.1 bits (87), Expect = 0.15
Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 16/195 (8%)
Query: 1366 TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL-------PTVVTTTEGKLI 1418
TE ++ +YE+ S + +EK+ + + +I L P +T EG+
Sbjct: 26022 TETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESA 26081
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
R G P P V WLR+G L S +Q+ S + V D G N
Sbjct: 26082 RFSCDTDGEPVPTVTWLRKGQVLSTSARHQV-TTTKYKSTFEISSVQASDEGNYSVVVEN 26140
Query: 1479 HLGVTATIAALSVESIVGTQE-YRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
G L+++ T++ P V E + +A +S P VK PE H +
Sbjct: 26141 SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKS-PKRVKS--PEPSHPK 26197
Query: 1538 EIVTFEAIYSGNPTP 1552
+ E PTP
Sbjct: 26198 AVSPTET----KPTP 26208
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P V P V E++ ++ GRP ++W + + ++ + +S K+ + +
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKT-VTSLS 18956
Query: 1342 IKEAFPEMAGIYKCTASNQFG 1362
IKEA E G Y+ SN G
Sbjct: 18957 IKEASKEDVGTYELCVSNSAG 18977
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/114 (18%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDIT 1329
++ +Q AP + + + V G+ + +P ++ W+HN ++ + I
Sbjct: 25865 VLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH 25924
Query: 1330 ISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE 1383
+ SG+ + I + + +G Y+ +N G+ S L++ +Y S+
Sbjct: 25925 YTNT-SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQ 25977
Score = 38.7 bits (86), Expect = 0.20
Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA--RDITISRQKSGLC 1338
A +L + TV +GE +C G P P + W +++ T+ +T ++ KS
Sbjct: 26063 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF- 26121
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
EI +A E G Y N GK E L I+
Sbjct: 26122 EISSVQASDE--GNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 38.3 bits (85), Expect = 0.27
Identities = 21/90 (23%), Positives = 38/90 (42%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT E V E E ++ + P P + W+KD K ++ +R ++N +
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 7949
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K+ + G YT + +G A ++V
Sbjct: 7950 PKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 37.9 bits (84), Expect = 0.35
Identities = 22/82 (26%), Positives = 36/82 (43%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
VH E +A G P P I W K ++ + R I++ + T+ ++K A + G Y
Sbjct: 16058 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNY 16117
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
KA + G ++V R
Sbjct: 16118 ILKAKNVAGERSVTVNVKVLDR 16139
Score = 37.9 bits (84), Expect = 0.35
Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++A G P P ++W++ EL + +I+ D TS L++ + + D+G +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS-LSVKDAVRVDSGNYIL 16119
Query: 1475 EAYNHLGVTATIAALSVESIVGTQE 1499
+A N G + + V G E
Sbjct: 16120 KAKNVAGERSVTVNVKVLDRPGPPE 16144
Score = 37.5 bits (83), Expect = 0.47
Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 10/146 (6%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKID 1314
+A N AG + S+ V C D P + E V +G +++ KI G P+P +
Sbjct: 9595 KAVNAAGV--SKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLT 9652
Query: 1315 WFH-NEKLIETARDITISRQKSGL-----CEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
WF K + + + L C + I ++ G+Y TA N G S E
Sbjct: 9653 WFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEM 9712
Query: 1369 ILNIEAYEYVP--SVSEEDVLSDEKT 1392
LN+ P + E V +D+ T
Sbjct: 9713 RLNVLGRPGPPVGPIKFESVSADQMT 9738
Score = 37.5 bits (83), Expect = 0.47
Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+++I RV + + A G P P+I W K+ KV+ ++R + R IK+A
Sbjct: 11418 RDVITVRVGQT--IRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAV 11475
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ G Y A + G A A + V R
Sbjct: 11476 RADHGKYIISAKNSSGHAQGSAIVNVLDR 11504
Score = 37.5 bits (83), Expect = 0.47
Identities = 22/65 (33%), Positives = 29/65 (44%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+ W K K IR + I + + TIK AT+ G YT A + G V
Sbjct: 13908 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 13967
Query: 1608 AKLQV 1612
K+ V
Sbjct: 13968 VKVTV 13972
Score = 37.1 bits (82), Expect = 0.61
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLE--NTTVMD-GERISLNCKILGRPWP 1311
A+N AG++S S + TC D +AP + ++ +T ++ GE L + GRP P
Sbjct: 14936 AKNAAGAISPP-SEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPP 14994
Query: 1312 KIDWFHNEKLIE-TAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
++W + K +E TA+ +I I+ + L K++ +G Y TA+N G + I
Sbjct: 14995 TMEWSKDGKELEGTAKLEIKIADFSTNLVN---KDSTRRDSGAYTLTATNPGG--FAKHI 15049
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSD 1394
N++ + P E + E TS+
Sbjct: 15050 FNVKVLDR-PGPPEGPLAVTEVTSE 15073
Score = 37.1 bits (82), Expect = 0.61
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 7/109 (6%)
Query: 1288 LENT-TVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDITISRQKSGLCEIHIKEA 1345
L NT TV+ GE + ++ +GRP P + W N L +T R S + + L + IK+A
Sbjct: 15656 LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSL--LTIKDA 15713
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
E G Y +N G+ LN+ + P V DE T+D
Sbjct: 15714 CREDVGHYVVKLTNSAGEAIE--TLNVIVLD-KPGPPTGPVKMDEVTAD 15759
Score = 37.1 bits (82), Expect = 0.61
Identities = 19/60 (31%), Positives = 28/60 (46%)
Query: 1543 EAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E SG P P I W KD ++ R + + + TT +IK+ KD G Y + +G
Sbjct: 16753 EVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG 16812
Score = 37.1 bits (82), Expect = 0.61
Identities = 19/82 (23%), Positives = 36/82 (43%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E + + + G P + W KD + ++ R + + + T+ +IK+A+K+ GTY
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
+ G + V R
Sbjct: 18969 ELCVSNSAGSITVPITIIVLDR 18990
Score = 36.7 bits (81), Expect = 0.81
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ----KSGLCEI 1340
++PLE+ TV +GE + C+ L + WF N+ + T+R + IS + K + E+
Sbjct: 5080 MSPLEDQTVKEGETATFVCE-LSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEV 5138
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
+ + A + + +++ Q + ++ ++ +E L E + DV
Sbjct: 5139 TLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDV 5193
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/78 (29%), Positives = 33/78 (42%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E EA SG P P + W KD K + + I+ + T K +T+ G YT A
Sbjct: 14980 EAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 15039
Query: 1598 VSDIGLAVTKAKLQVFQR 1615
+ G A ++V R
Sbjct: 15040 TNPGGFAKHIFNVKVLDR 15057
Score = 36.7 bits (81), Expect = 0.81
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
T + SG P P++ W + ++ +R I ++RTT T+K + + G Y +
Sbjct: 22169 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22228
Query: 1601 IGLAVTKAKLQVFQR 1615
G+ + V R
Sbjct: 22229 AGVKTFSVTVVVIGR 22243
Score = 36.3 bits (80), Expect = 1.1
Identities = 40/205 (19%), Positives = 80/205 (39%), Gaps = 9/205 (4%)
Query: 1525 FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKK 1584
F++ + +V E+E+ FE S ++ W+KD I+ +++ I +K I K
Sbjct: 5879 FLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937
Query: 1585 ATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXXXXXXXXXXXXXXXXXXXXEEESVGV 1644
D E Y+C ++ A T L V + E S
Sbjct: 5938 CLLDDEAEYSC----EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPG 5993
Query: 1645 EDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSESEHIETEDIALQKKVDEKTKG-IPV 1703
+ + + E+ + + +KR I+V ++ H+E + +T G + V
Sbjct: 5994 AEVIWYKGDEEIIETGRYEILTEGRKR---ILVIQNAHLEDAGNYNCRLPSSRTDGKVKV 6050
Query: 1704 EEKAKPILTTHEHVVLSEQQEGESV 1728
E A ++ +++ + E ++ E V
Sbjct: 6051 HELAAEFISKPQNLEILEGEKAEFV 6075
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A L +V FVKE+ V E E I S E WY ++ ++++ ++ I +
Sbjct: 2212 AKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKYTITS 2270
Query: 1574 KENRTTCTIKKATKDLEGTYT 1594
+ R T+K TK+ +G Y+
Sbjct: 2271 RRGRQNLTVKDVTKEDQGEYS 2291
Score = 35.9 bits (79), Expect = 1.4
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A LK ++ P F ++ + E++ +T + S + P + W+KD + I ++ I+
Sbjct: 5157 AQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VP-VKWFKDGEEIVPSPKYSIKA 5214
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
R IKKA +G Y C D G TKA + V R
Sbjct: 5215 DGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEAR 5252
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKID 1314
RAEN AG +S + + DAP V+ + V G+ I+L+ I G P+P I
Sbjct: 8158 RAENAAG-ISEPSRATPPTKAVDPIDAPKVILRT-SLEVKRGDEIALDASISGSPYPTIT 8215
Query: 1315 WFHNEKLI 1322
W +E +I
Sbjct: 8216 WIKDENVI 8223
Score = 35.9 bits (79), Expect = 1.4
Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
Query: 1415 GKLIRLEAKAIGIPKPQVRW------LRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
G+ + + A G+P P++ W + + T+ LQ T+ ++ + T L++P+ ++D
Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-LSIPKAVRED 8974
Query: 1469 TGEIVFEAYNHLG 1481
G A N LG
Sbjct: 8975 KGTYTVTASNRLG 8987
Score = 35.9 bits (79), Expect = 1.4
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ +A G P P+I+W K +K + E+ ++ R T IK + G YT +
Sbjct: 22568 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22627
Query: 1600 DIGLAVTKAKLQV 1612
G ++V
Sbjct: 22628 ASGTKAVSVMVKV 22640
Score = 35.5 bits (78), Expect = 1.9
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 10/120 (8%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
++ PL++T V + + + NC++ K WF NE+ I + I QK + + I+
Sbjct: 6145 IVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIR 6202
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
+A + Y + +N G+ + + N+ V EED+ E D+E + V
Sbjct: 6203 DAHLDDQANYNVSLTNHRGE-NVKSAANL-------IVEEEDLRIVEPLKDIETMEKKSV 6254
Score = 35.1 bits (77), Expect = 2.5
Identities = 19/76 (25%), Positives = 31/76 (40%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V +A G P P + W KD +++ E + + N T + + G YT A +
Sbjct: 12816 VCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 12875
Query: 1600 DIGLAVTKAKLQVFQR 1615
G KL+V +
Sbjct: 12876 SSGSKSATIKLKVLDK 12891
Score = 35.1 bits (77), Expect = 2.5
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 4/113 (3%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLV-LAP-LENTTVMD-GERISLNCKILGRPWPK 1312
A+N AG++S S + + P + + P +T V++ GE L + G+P P
Sbjct: 17100 AKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPT 17159
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
I+W +K IE + I I +K+A G Y ASN G S
Sbjct: 17160 IEWLRGDKEIEESARCEIKNTDFKALLI-VKDAIRIDGGQYILRASNVAGSKS 17211
Score = 35.1 bits (77), Expect = 2.5
Identities = 16/61 (26%), Positives = 26/61 (42%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V+E E F G P P + W + +V+ T R + + ++T I EG Y
Sbjct: 26075 VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 26134
Query: 1594 T 1594
+
Sbjct: 26135 S 26135
Score = 34.7 bits (76), Expect = 3.3
Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Query: 1255 RAENFAG--SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
+A+N AG + SS++ ++ I+ A L + T G +++ I GRP PK
Sbjct: 22122 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22181
Query: 1313 IDWFHNE-KLIETAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
+ W E +L ET R IT ++ ++ L +K++ +G Y T N G
Sbjct: 22182 VTWKLEEMRLKETDRVSITTTKDRTTLT---VKDSMRGDSGRYFLTLENTAG 22230
Score = 34.3 bits (75), Expect = 4.3
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L TV G +I L + G+P PKI W + +++ + ITI + I ++
Sbjct: 7200 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK-KSTVTIVDSKR 7258
Query: 1348 EMAGIYKCTASNQFGKCSTECILNI 1372
G Y A N G+ + +N+
Sbjct: 7259 SDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 34.3 bits (75), Expect = 4.3
Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 5/119 (4%)
Query: 1275 TCIDGDAP--LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR 1332
TC D AP L L + T+ GE +L + G+P PK+ WF +E + I
Sbjct: 10313 TCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT 10372
Query: 1333 QKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVP--SVSEEDVLSD 1389
+ L IK A +G Y N G C +N+ + P VS ++V D
Sbjct: 10373 TPATLALEKIK-AKRSDSGKYCVVVENSTGSRKGFCQVNVVDHPGPPVGPVSFDEVTKD 10430
Score = 34.3 bits (75), Expect = 4.3
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKV--IRTDERFIIENKENRTTCTIKKATKDLEGTYTC 1595
+ + EA G P PE+ W KD + R I+ + + + ++ KA + G Y
Sbjct: 11720 DTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVV 11779
Query: 1596 KAVSDIGLAVTKAKLQVFQR 1615
A + G V A + V +
Sbjct: 11780 TATNTAGSFVAYATVNVLDK 11799
Score = 34.3 bits (75), Expect = 4.3
Identities = 22/82 (26%), Positives = 34/82 (41%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V+ E EA G P P I W + +K I R I+N + + +K A + G Y
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
+A + G ++V R
Sbjct: 17200 ILRASNVAGSKSFPVNVKVLDR 17221
Score = 33.9 bits (74), Expect = 5.7
Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E +L + A + VSE +S+ + + P I ++ EG+ + +
Sbjct: 7858 EYVLRVRAVNAI-GVSEPSEISENVVAKDPDCKPTIDLETHDIIVI-EGEKLSIPVPFRA 7915
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG-VTAT 1485
+P P V W + G E+ S ++ D ++ L +P+ + D G N LG TA+
Sbjct: 7916 VPVPTVSWHKDGKEVKASDRLTMKN-DHISAHLEVPKSVRADAGIYTITLENKLGSATAS 7974
Query: 1486 I 1486
I
Sbjct: 7975 I 7975
Score = 33.9 bits (74), Expect = 5.7
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G+ + L+ I G P+PK+ W ++ T I ++ S ++ I+ A E GIY
Sbjct: 10736 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS---KLEIRNAAHEDGGIYSL 10792
Query: 1356 TASNQFG 1362
T N G
Sbjct: 10793 TVENPAG 10799
Score = 33.9 bits (74), Expect = 5.7
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 6/111 (5%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM---DGERISLNCKILGRPWPK 1312
A N A SVS S D + P V+ ++ V+ GE + +N I GRP P
Sbjct: 19264 ARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV 19323
Query: 1313 IDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
I W + ++ E AR IS L + +K+ G Y T N G
Sbjct: 19324 ISWAKDGIEIEERARTEIISTDNHTL--LTVKDCIRRDTGQYVLTLKNVAG 19372
Score = 33.5 bits (73), Expect = 7.6
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD------DGTSILTMPEVYQD 1467
EG + + AK G+P P + W + + + E + + D T L +P+ +
Sbjct: 9633 EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 9692
Query: 1468 DTGEIVFEAYNHLGVTATIAALSV 1491
DTG A N+LG + L+V
Sbjct: 9693 DTGLYTITAVNNLGTASKEMRLNV 9716
Score = 33.5 bits (73), Expect = 7.6
Identities = 15/47 (31%), Positives = 20/47 (42%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
G P P + W K + TD R +E+ TT + K G YT
Sbjct: 13511 GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYT 13557
Score = 33.5 bits (73), Expect = 7.6
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
E++ A +G P P I W KD I R I + +N T T+K + G Y
Sbjct: 19308 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQY 19363
Score = 33.5 bits (73), Expect = 7.6
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ + L G P P W G++L +S +E + LT+ E DTGE
Sbjct: 23256 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVET-HTKVAKLTIRETTIRDTGEYTL 23314
Query: 1475 EAYNHLGVTA 1484
E N G T+
Sbjct: 23315 ELKNVTGTTS 23324
>AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform
protein.
Length = 5604
Score = 97.9 bits (233), Expect = 3e-19
Identities = 69/235 (29%), Positives = 108/235 (45%), Gaps = 25/235 (10%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P +++ L+N TV++GE ++L C I G P P + W+ + IE++ D I+ Q SG+ +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-SGIARLM 1001
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE-------------------YVPS-- 1380
I+EAF E +G + C+A N+ G ST C L ++ E +V S
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061
Query: 1381 -VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
V + L++E+ E AP + P V EG + + G PKP V W + G
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFI-TKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 1440 ELLQSTEYQIE-ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L Y++ G L + + DD GE N G T+ A+L E+
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175
Score = 89.4 bits (212), Expect = 1e-16
Identities = 64/214 (29%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P VL L+ TV G+ I GRP PKI W+ E+L+ T
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I EAFPE A +Y C A N +G +T L++E VP V D ++ +
Sbjct: 3297 LLI-EAFPEDAAVYTCEAKNDYGVATTSASLSVE----VPEVVSPD-------QEMPVYP 3344
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P I+ L V T+EG+ R + + G +V W + ++ S +++ + +D T L
Sbjct: 3345 PAIITPLQDTV-TSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQL 3401
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
+ E Y +D G F A N +G ++ A LS+E+
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435
Score = 74.9 bits (176), Expect = 3e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 74.1 bits (174), Expect = 4e-12
Identities = 77/331 (23%), Positives = 131/331 (39%), Gaps = 47/331 (14%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + PL V + + ++ G P P + W+ N+ L+E I + R +C +
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMER-VGNVCSLE 5241
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
I G Y C A N G+ S + D++ E+ R
Sbjct: 5242 ISNIQKGEGGEYMCHAVNIIGEAK--------------SFANVDIMPQEE---------R 5278
Query: 1402 IVKALPTVVTTTEGKLIRLE-AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+V ALP VT LE + P PQ L ++ +E ++E + I+T
Sbjct: 5279 VV-ALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLE-----VELSEKDVKEFEKQVKIVT 5332
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+PE D H + ++ L + + R+ E +EL+ L+ +
Sbjct: 5333 VPEFTPD-----------HKSMIVSLDVLPFNFVDPNMDSREGE----DKELKIDLEVFE 5377
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE-RFIIENKENRTT 1579
P F+ I ++ E F+ G PTPE+ WYK+ I D +++I ++ T
Sbjct: 5378 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 5437
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
I+ TY C+AV+ +G A+ + L
Sbjct: 5438 LKIRNVCLSDSATYRCRAVNCVGEAICRGFL 5468
Score = 68.1 bits (159), Expect = 3e-10
Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDA------PLVLAPLENTTVMDGERISLNCK 1304
V TC A+N G +TS S VE + D P ++ PL++T +G+ C+
Sbjct: 3308 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR 3367
Query: 1305 ILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
+ G K+ W+ +K I+ +R ++ Q ++ I EA+PE G Y ASN G+
Sbjct: 3368 VSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 3425
Query: 1365 STECILNIEAYEYV 1378
S+ L++EA E +
Sbjct: 3426 SSTANLSLEAPESI 3439
Score = 67.3 bits (157), Expect = 5e-10
Identities = 78/361 (21%), Positives = 139/361 (38%), Gaps = 31/361 (8%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +V L V T EG+ + LE G P P V W R+ ++ S ++QI G + L
Sbjct: 943 PTLVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQIT-FQSGIARL 1000
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSV--------ESIVGTQEYRKPE--WVTHM 1509
+ E + +D+G A N G +T L+V E+ T+++ E +V
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 1510 EELQAALKATQ--------SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNK 1561
+ + T+ + P F+ + + +++ E V F GNP P + W K
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 1562 VIRTDERFIIENKENRTTC--TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXX 1619
+ T R+ + + C I D G YT + G A L + +
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADYEL 1179
Query: 1620 XXXXXXXXXXXXXXXXXXEEESVGVEDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSE 1679
+E VG E F + +K+ + ++K+ AK V
Sbjct: 1180 LMKSQQEMLYQTQVTAFVQEPKVG-ETAPGFVYSEYEKEYEKEQAL--IRKKMAKDTVVV 1236
Query: 1680 SEHIETEDIALQKKVDEKTKGIPVEEKAKPILTTHEHVVLSEQQEGESVEPFDESYQTQK 1739
++E ++ + + K E + + I TT E ++ + +E +V+ ES +
Sbjct: 1237 RTYVEDQEFHISSFEERLIK----EIEYRIIKTTLEELLEEDGEEKMAVD-ISESEAVES 1291
Query: 1740 G 1740
G
Sbjct: 1292 G 1292
Score = 66.9 bits (156), Expect = 7e-10
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G PTP + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 64.5 bits (150), Expect = 4e-09
Identities = 76/359 (21%), Positives = 131/359 (36%), Gaps = 42/359 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
++N +++G ++ +CK+ G P PKI W+ + K I+ + + G + I P
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1356
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
E GIY ASN G L +E P + + + E S + +PR V P
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE--PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSP 1414
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL-------- 1459
++ R+ + + + G L ++ E Q+E L +L
Sbjct: 1415 IRMSPARMSPARMSPARMSPAR-----MSPGRRLEETDESQLERLYKPVFVLKPVSFKCL 1469
Query: 1460 --------------TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
MPE + G+ + Y H V S+ IV EW
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL-IIVPATPSDSGEW 1528
Query: 1506 VTHMEE----------LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEIL 1555
+ L Q P FV+++ + E + + +GNP P+I+
Sbjct: 1529 TVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIV 1588
Query: 1556 WYKDNKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
W K++ +I + + IE + I YT A++ G T+ K+ V
Sbjct: 1589 WLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 63.7 bits (148), Expect = 6e-09
Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 23/206 (11%)
Query: 1306 LGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
+G P ++W H+ K +E A + + + G C + A+ +GI C A+N++G
Sbjct: 1729 IGDPTMVVEWLHDGKPLEAANRLRMINE-FGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 1366 TECIL-------------------NIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
T L ++ E + ++ E L+ T E+ P IV
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIV-LY 1846
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P V EG+ R + G P+P+V W G + +S +++ DG L + +
Sbjct: 1847 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKS 1904
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVE 1492
DTGE+ A N GV L ++
Sbjct: 1905 YDTGEVKVTAENPEGVIEHKVKLEIQ 1930
Score = 63.3 bits (147), Expect = 8e-09
Identities = 83/356 (23%), Positives = 134/356 (37%), Gaps = 48/356 (13%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
VL P+ + ++G+ + K++GRP P+ WFH+ + I + ++ G + I
Sbjct: 1460 VLKPV-SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV 1518
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
A P +G + A N+ G+ S IL +EA E+ + P V
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH-------------------QVKPMFV 1559
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTSILTMP 1462
+ L V EG + ++ +A G P P + WL+ ++ +I E G + L +
Sbjct: 1560 EKLKN-VNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1618
Query: 1463 EVYQDDTGEIVFEAYNHLGVTATIAALSVE-----------SIVGTQEYRKPEWVT---- 1507
D+ A N G T ++VE I+ YR E
Sbjct: 1619 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELE 1678
Query: 1508 --HM-------EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS--GNPTPEILW 1556
H+ EE K Q P F K++ R+ FE + G+PT + W
Sbjct: 1679 PLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEW 1738
Query: 1557 YKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D K + R + N+ + A G TC+A + G T A L V
Sbjct: 1739 LHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 62.9 bits (146), Expect = 1e-08
Identities = 59/214 (27%), Positives = 94/214 (43%), Gaps = 20/214 (9%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI- 1458
P++++ L V T GK R A G P+P++ W ++ E L ST ++ + L DG
Sbjct: 3239 PQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKE--EQLLSTGFKCKFLHDGQEYT 3295
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E + +D EA N GV T A+LSVE PE V+ +E+
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV---------PEVVSPDQEMPVY--- 3343
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P + + E + F+ SG ++ WY +K I+ F + E+
Sbjct: 3344 ---PPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3399
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A + EGTYT A + +G + A L +
Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 59.7 bits (138), Expect = 1e-07
Identities = 51/226 (22%), Positives = 88/226 (38%), Gaps = 18/226 (7%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + P+ + + + C ++G P P++ W+ IE + ++ G +
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEY-----------VPSVSEEDVLSDE 1390
I+ + Y+C A N G+ L + E + S+ EE VL
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 5499
Query: 1391 KTSDVEEF-----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST 1445
T EF PR +K + G + G P+P V W + G +L+Q
Sbjct: 5500 YTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVRGSPRPTVYWYKDG-KLVQGR 5557
Query: 1446 EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ +EE G L + + + D GE A N G+ + AAL++
Sbjct: 5558 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 56.8 bits (131), Expect = 7e-07
Identities = 27/90 (30%), Positives = 46/90 (51%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F++EI + V+E + F + G P P + WY ++ I ++ FII + EN + T+
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
EG+ TC + G T + L+V
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
Score = 55.6 bits (128), Expect = 2e-06
Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
P+ Y+ + G E +GV+ T + E + + VT + A ++ +
Sbjct: 887 PDTYKSEAG---VEVKKEVGVSITGTTVREERFEVL--HGREAKVTETARVPAPVEIPVT 941
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT V + V E E VT E SG P+P + WY+++ I + F I +
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++A + G +TC AV++ G T L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 54.4 bits (125), Expect = 4e-06
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 18/257 (7%)
Query: 1370 LNIEAYEYV-PSVSEEDVLSDEKTSDVE--EFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
L++ + +V P++ + E D+E E PR + + + + IG
Sbjct: 5347 LDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAV-FKCSVIG 5405
Query: 1427 IPKPQVRWLRQGTELL-QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTAT 1485
IP P+V+W ++ + + +Y I E + G+ L + V D+ A N +G
Sbjct: 5406 IPTPEVKWYKEYMCIEPDNIKYVISE-EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAIC 5464
Query: 1486 IAALSV---ESIVGTQEYRKPEWVTHMEELQAALKATQSV---------PTFVKEIIPER 1533
L++ E + K + MEEL T S P F+K I
Sbjct: 5465 RGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCY 5524
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
F+ + G+P P + WYKD K+++ + E+ I K EG Y
Sbjct: 5525 APIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEY 5584
Query: 1594 TCKAVSDIGLAVTKAKL 1610
C A + G+A + A L
Sbjct: 5585 RCVATNKSGMAESFAAL 5601
Score = 54.0 bits (124), Expect = 5e-06
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Query: 1393 SDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEEL 1452
SD+ P++++ +P EG I LE G P+P V W + G L Q+ ++Q EE+
Sbjct: 4151 SDITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEV 4210
Query: 1453 DDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ L + +V D+G+ A N+ G +++ L+VE +
Sbjct: 4211 NCSHQ-LYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPV 4251
Score = 54.0 bits (124), Expect = 5e-06
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKEN 1576
K + P+F++ + +V+E + F G P P + WY++ ++ DER +E N
Sbjct: 5177 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 5236
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I K G Y C AV+ IG A + A + +
Sbjct: 5237 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272
Score = 53.6 bits (123), Expect = 7e-06
Identities = 75/338 (22%), Positives = 135/338 (39%), Gaps = 20/338 (5%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
+VL P E V++GE C++ G P PK++W+ N +LI ++ + + G+ + I
Sbjct: 1843 IVLYP-EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLDI 1899
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR- 1401
+ G K TA N G + L I+ E SV + E + P
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRR---APEPRPEFHVHEPGK 1956
Query: 1402 ---IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE-LDDGTS 1457
V+ + V TTE K + +A I +V + EL + + EE + +
Sbjct: 1957 LQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVP--EESEELRSKFKRRTEEGYYEAIT 2014
Query: 1458 ILTMPEVYQDDTGEIVFEAYNH--LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ + +D++ E + L T + +++ + P + EL +
Sbjct: 2015 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2074
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN-KVIRTDERFIIENK 1574
++A P + I + V + F G P PE WYK+ K+ R+D + +
Sbjct: 2075 MEA----PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+N I+ T + + KA++ G + A L V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2168
Score = 52.8 bits (121), Expect = 1e-05
Identities = 66/332 (19%), Positives = 127/332 (38%), Gaps = 28/332 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L +E+ V +G+ + C G P P + W++N+ I ++ I ++ +
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLEN-YSILT 4002
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
+ + G C NQ+G T +L ++A + + + + + + EE A
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEELALV 4062
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ-STEYQIEELDDGTSILT 1460
+A + ++ L P P TELL E Q+ T+
Sbjct: 4063 FDQAKGAHPSMSQEGQTNLHLLKTNPPVPP----SGDTELLSFPVEIQV------TAATP 4112
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+PE QD + VF+ A+ + + + ++R +V + K Q
Sbjct: 4113 IPE--QDKESKEVFQTEE-----LEPKAMPQDQVTQSPKHR---FVFLSDITNEPPKMLQ 4162
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
+P R E + + E + SG P P + W+++ +++ +++F E
Sbjct: 4163 EMPKHA------RCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQL 4216
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
IK G Y C A ++ G + + L V
Sbjct: 4217 YIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 50.8 bits (116), Expect = 5e-05
Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + +++ TV G +++G+P P+ +W+ N IE + I + +CE
Sbjct: 2076 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE-EDVLSDEK 1391
+ I++ E + A N G+ S+ L ++A + + E +DV++ EK
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEK 2188
Score = 49.6 bits (113), Expect = 1e-04
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 1510 EELQAALKATQSVPT-FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER 1568
E++ + +++V + F I R+ E VTF SG P P+I WYKD K I+ ER
Sbjct: 1277 EKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1336
Query: 1569 FIIE-NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ ++ R + I + EG YT A + G A+ KL V
Sbjct: 1337 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381
Score = 48.4 bits (110), Expect = 2e-04
Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 17/206 (8%)
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
IG P V WL G L + ++ + G L Y D+G I A N G
Sbjct: 1729 IGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 1485 TIAALSVESIVG-TQEYRKPEW---VTHMEELQ--AALKATQSVPTFVKE-------IIP 1531
T A L V+ +E + PE + +EEL+ A A V T KE + P
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1847
Query: 1532 E--RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
E RV E E F +G P P++ WY + ++IR +RF + + + D
Sbjct: 1848 EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYD- 1906
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQVFQR 1615
G A + G+ K KL++ QR
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQR 1932
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
Query: 1277 IDGDAPLVLAPL-ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKS 1335
I + P +L + ++ +G+ I L C I G P P + WF N L++ +
Sbjct: 4153 ITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNC 4212
Query: 1336 GLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV 1386
+++IK+ + +G YKC A N G + L +E Y + E++
Sbjct: 4213 S-HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQFENI 4262
Score = 48.0 bits (109), Expect = 3e-04
Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 8/153 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLENTTVMDGERISLNCKILGR 1308
G T A+N AG S S VE ++ P+ + L+N + +G ++ + + G
Sbjct: 1526 GEWTVVAQNRAGRSSISVILTVE---AVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGN 1582
Query: 1309 PWPKIDWFHNEKLIETAR--DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P P I W N +I + I I K G + I + + Y TA N+ G+ +T
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTK-GEAALKIDSTVSQDSAWYTATAINKAGRDTT 1641
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
C +N+E E+ E ++ T +E A
Sbjct: 1642 RCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIA 1673
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/151 (25%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 1263 VSTSGSSIVEEQTCI-DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
V + +S+ EEQ + AP + +++G + C++ G P P + W +
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121
Query: 1322 IETARDITISRQK-SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA-YEYVP 1379
+ T +S K +G C++ I F + AG Y N+ G+ S L EA YE +
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1181
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
+E + + T+ V+E P++ + P V
Sbjct: 1182 KSQQEMLYQTQVTAFVQE--PKVGETAPGFV 1210
Score = 44.8 bits (101), Expect = 0.003
Identities = 50/215 (23%), Positives = 92/215 (42%), Gaps = 30/215 (13%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
AP+I + + + T +G + +G P P+ W + G ++ +S +D
Sbjct: 2077 APKIFERIQSQ-TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + +V +D+ I+ +A N G T++ A L V++ + +T +ELQ +
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA---------KQLITFTQELQDVV-- 2184
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
KE ++ + TFE + P ++ WYKD + +++ + +
Sbjct: 2185 -------AKE-------KDTMATFEC-ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVH 2229
Query: 1579 TCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+I T D E Y+C V D + T AKL V
Sbjct: 2230 FLSILTIDTSDAE-DYSCVLVEDENVKTT-AKLIV 2262
Score = 44.0 bits (99), Expect = 0.005
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 4/97 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK----ENRT 1578
P+F +++ + V E E V F PTPE+ W+ +N+ I T R II+ + + +
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ IK+ G+Y A++ G A + A L V Q+
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600
Score = 40.3 bits (90), Expect = 0.066
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKS---GLCEIHIKEAFPEM 1349
V++GE + C+++ P P++ WFHN + I T I + + IK
Sbjct: 3515 VLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRD 3574
Query: 1350 AGIYKCTASNQFGKC-STECILNIE 1373
+G Y+ A N G ST +L I+
Sbjct: 3575 SGSYRLLAINSEGSAESTASLLVIQ 3599
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A L +V FVKE+ V E E I S E WY ++ ++++ ++ I +
Sbjct: 2258 AKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKYTITS 2316
Query: 1574 KENRTTCTIKKATKDLEGTYT 1594
+ R T+K TK+ +G Y+
Sbjct: 2317 RRGRQNLTVKDVTKEDQGEYS 2337
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 97.9 bits (233), Expect = 3e-19
Identities = 69/235 (29%), Positives = 108/235 (45%), Gaps = 25/235 (10%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P +++ L+N TV++GE ++L C I G P P + W+ + IE++ D I+ Q SG+ +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-SGIARLM 1001
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE-------------------YVPS-- 1380
I+EAF E +G + C+A N+ G ST C L ++ E +V S
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061
Query: 1381 -VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
V + L++E+ E AP + P V EG + + G PKP V W + G
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFI-TKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 1440 ELLQSTEYQIE-ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L Y++ G L + + DD GE N G T+ A+L E+
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175
Score = 92.3 bits (219), Expect = 2e-17
Identities = 73/270 (27%), Positives = 123/270 (45%), Gaps = 17/270 (6%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P VL L+ TV G+ I GRP PKI W+ E+L+ T
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I EAFPE A +Y C A N +G +T L++E VP V D ++ +
Sbjct: 3297 LLI-EAFPEDAAVYTCEAKNDYGVATTSASLSVE----VPEVVSPD-------QEMPVYP 3344
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P I+ L V T+EG+ R + + G +V W + ++ S +++ + +D T L
Sbjct: 3345 PAIITPLQDTV-TSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQL 3401
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYR-KPEWVTHMEELQAALKA 1518
+ E Y +D G F A N +G ++ A LS+E+ R + E M+E ++ +
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLS 3461
Query: 1519 TQSVPTFVKEIIPERVHEE-EIVTFEAIYS 1547
+ E+ +++E E+++ +YS
Sbjct: 3462 AEEEGLHSAELQLSKINETLELLSESPVYS 3491
Score = 87.4 bits (207), Expect = 4e-16
Identities = 93/385 (24%), Positives = 158/385 (41%), Gaps = 60/385 (15%)
Query: 1218 IIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
++ +D L + + L +L+ ++S G +C A N G+ S+S E
Sbjct: 7140 VLLRDDENLQTSFVDNVATLKILQTDLSHS--GQYSCSASNPLGTASSSARLTAREPK-- 7195
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+P + V+ GE C + G +I W + K I + TI+
Sbjct: 7196 --KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCV-GNT 7252
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE 1397
+ I + +G Y C A+N GK D+ S + + V+E
Sbjct: 7253 PHLRILKVGKGDSGQYTCQATNDVGK---------------------DMCSAQLS--VKE 7289
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
P+ VK L +G+ I+LE K G P+ +V W R +EL +S +Y + + + +
Sbjct: 7290 -PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFI-NSVA 7347
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
+LT+ E +D+G+ + EA+N +G + AL+V++ P T ALK
Sbjct: 7348 LLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA---------PPVFTQKPSPVGALK 7398
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
+ V + SG P E++W KD K +R ++F I +K
Sbjct: 7399 GSD-------------------VILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFD 7439
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIG 1602
T+ I G Y CKA +++G
Sbjct: 7440 TSLHILNLEASDVGEYHCKATNEVG 7464
Score = 85.0 bits (201), Expect = 2e-15
Identities = 69/244 (28%), Positives = 108/244 (44%), Gaps = 18/244 (7%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E + +SE V S + S+ E P +K + + G + L IGIPKP+++W
Sbjct: 3479 ETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNA-DISMGDVATLSVTVIGIPKPKIQWF 3537
Query: 1436 RQGTELLQSTEYQ-IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
G L S +Y+ + + DD + I+ ++ +D GE A N G T A L + S
Sbjct: 3538 FNGVLLTPSADYKFVFDGDDHSLIILFTKL--EDEGEYTCMASNDYGKTICSAYLKINS- 3594
Query: 1495 VGTQEYRKPEWVTHMEELQAALKATQSV-----PTFVKEIIPERVHEEEIVTFEAIYSGN 1549
K E E A K+ + + P F+KE+ P R + FE G
Sbjct: 3595 -------KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 3647
Query: 1550 PTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P P + W+K+NK + T + II N T + ++ G Y CKA + +G + A
Sbjct: 3648 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 3707
Query: 1609 KLQV 1612
+L V
Sbjct: 3708 ELLV 3711
Score = 78.6 bits (185), Expect = 2e-13
Identities = 88/373 (23%), Positives = 149/373 (39%), Gaps = 41/373 (10%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
+ K G TC A N G S + ++E+ + +E T +G L
Sbjct: 9142 VDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEET---EGNSFKLEG 9198
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G + W+ N I+ + I+ + + L + +++A AG+Y C SN G
Sbjct: 9199 RVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV-LQVRKAGMNDAGLYTCKVSNDAG- 9256
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAK 1423
S C +I V+ + K P + T VT +EG+ ++L
Sbjct: 9257 -SALCTSSI-------------VIKEPKK-------PPVFDQHLTPVTVSEGEYVQLSCH 9295
Query: 1424 AIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVT 1483
G +++WL+ G E+ S GT++L + +V + D+G+ V +A N G
Sbjct: 9296 VQGSEPIRIQWLKAGREIKPSDRCSFS-FASGTAVLELRDVAKADSGDYVCKASNVAGSD 9354
Query: 1484 ATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFE 1543
T + ++++ KP ++ A FV E RV E+ TF
Sbjct: 9355 TTKSKVTIKD--------KPAVAPATKKA-----AVDGRLFFVSEPQSIRVVEKTTATFI 9401
Query: 1544 AIYSGNPTPEILWYKDN-KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
A G+P P + W K + + R I K + I+ TK G Y C A ++ G
Sbjct: 9402 AKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHG 9461
Query: 1603 LAVTKAKLQVFQR 1615
+ LQV +R
Sbjct: 9462 EIESNVNLQVDER 9474
Score = 74.9 bits (176), Expect = 3e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 73.3 bits (172), Expect = 8e-12
Identities = 90/392 (22%), Positives = 143/392 (36%), Gaps = 54/392 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGD 1280
KDS + + LN+ + + + L G +C A N GS S+S I+ E +
Sbjct: 9025 KDSPNVQTSFLDNTATLNIFKTD--RSLAGQYSCTATNPIGSASSSARLILTEGK----N 9078
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P L + GE C + G K+ W + + I + IS ++ +
Sbjct: 9079 PPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENS-AHL 9137
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
+ + +G Y C A N+ GK S LNI+ +P P
Sbjct: 9138 TVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE-RLIP--------------------P 9176
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
K L V TEG +LE + G V W + E+ ++ +I + T +L
Sbjct: 9177 SFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEI-TFKNNTLVLQ 9235
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+ + +D G + N G +AL SIV +E +KP
Sbjct: 9236 VRKAGMNDAGLYTCKVSNDAG-----SALCTSSIV-IKEPKKP----------------- 9272
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F + + P V E E V G+ I W K + I+ +R
Sbjct: 9273 --PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVL 9330
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
++ K G Y CKA + G TK+K+ +
Sbjct: 9331 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 9362
Score = 72.9 bits (171), Expect = 1e-11
Identities = 56/217 (25%), Positives = 92/217 (42%), Gaps = 7/217 (3%)
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+G P+ + + N + G+ +L+ ++G P PKI WF N L+ + D
Sbjct: 3499 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3558
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGK--CSTECILNIEAYEYVPSVSEEDVLSD-EKTSD 1394
I + E G Y C ASN +GK CS +N + + + +E V EK
Sbjct: 3559 SLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3617
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
P +K L + +G E +G P P V W ++ +L S Y I +
Sbjct: 3618 --PCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 3674
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
G+ + + ++D+G + +A N LG + A L V
Sbjct: 3675 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3711
Score = 69.3 bits (162), Expect = 1e-10
Identities = 47/161 (29%), Positives = 79/161 (49%), Gaps = 12/161 (7%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGD------APLVLAPLENTTVMDGERISLNCK 1304
V TC A+N G +TS S VE + D P ++ PL++T +G+ C+
Sbjct: 3308 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR 3367
Query: 1305 ILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
+ G K+ W+ +K I+ +R ++ Q ++ I EA+PE G Y ASN G+
Sbjct: 3368 VSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 3425
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
S+ L++EA E S+ E + E +++EF+ + A
Sbjct: 3426 SSTANLSLEAPE---SILHERI-EQEIEMEMKEFSSSFLSA 3462
Score = 68.5 bits (160), Expect = 2e-10
Identities = 88/381 (23%), Positives = 154/381 (40%), Gaps = 63/381 (16%)
Query: 1223 STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAP 1282
ST R++ +++++ N+ + TC+ N AG + SG V+E
Sbjct: 6205 STSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSF----- 6259
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
++ P + D + + G P KI WF ++ + + I + S +++
Sbjct: 6260 -LVKPGRQQAIPDST-VEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGS-TSFLNL 6316
Query: 1343 KEAFPEMAGIYKCTASNQFGKCS-TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
G Y C +N G S T +L E ++V + A +
Sbjct: 6317 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLE----------------ASK 6360
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM 1461
IVKA G RLE K G P+ +V W R EL S +Y++ + D +++ M
Sbjct: 6361 IVKA---------GDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFI-DSVAVIQM 6410
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
+ +D+G+ + EA N G T + S + IV ++P + + LK +
Sbjct: 6411 NNLSTEDSGDFICEAQNPAGST----SCSTKVIV-----KEPPVFSSFPPIVETLKNAE- 6460
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
V+ E SG P E++WYKD + +R+ +++ I +K T+
Sbjct: 6461 ------------------VSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIH 6502
Query: 1582 IKKATKDLEGTYTCKAVSDIG 1602
I G Y CKA +++G
Sbjct: 6503 ILNVDTSDIGEYHCKAQNEVG 6523
Score = 67.3 bits (157), Expect = 5e-10
Identities = 78/361 (21%), Positives = 139/361 (38%), Gaps = 31/361 (8%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +V L V T EG+ + LE G P P V W R+ ++ S ++QI G + L
Sbjct: 943 PTLVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQIT-FQSGIARL 1000
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSV--------ESIVGTQEYRKPE--WVTHM 1509
+ E + +D+G A N G +T L+V E+ T+++ E +V
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 1510 EELQAALKATQ--------SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNK 1561
+ + T+ + P F+ + + +++ E V F GNP P + W K
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 1562 VIRTDERFIIENKENRTTC--TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXX 1619
+ T R+ + + C I D G YT + G A L + +
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADYEL 1179
Query: 1620 XXXXXXXXXXXXXXXXXXEEESVGVEDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSE 1679
+E VG E F + +K+ + ++K+ AK V
Sbjct: 1180 LMKSQQEMLYQTQVTAFVQEPKVG-ETAPGFVYSEYEKEYEKEQAL--IRKKMAKDTVVV 1236
Query: 1680 SEHIETEDIALQKKVDEKTKGIPVEEKAKPILTTHEHVVLSEQQEGESVEPFDESYQTQK 1739
++E ++ + + K E + + I TT E ++ + +E +V+ ES +
Sbjct: 1237 RTYVEDQEFHISSFEERLIK----EIEYRIIKTTLEELLEEDGEEKMAVD-ISESEAVES 1291
Query: 1740 G 1740
G
Sbjct: 1292 G 1292
Score = 66.9 bits (156), Expect = 7e-10
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G PTP + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 66.1 bits (154), Expect = 1e-09
Identities = 83/366 (22%), Positives = 137/366 (37%), Gaps = 62/366 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A N AG+ S S V+E P + L+ V+ + L C++ G P
Sbjct: 5857 GTYVCEARNDAGTASCSIELKVKEP-------PTFIRELKPVEVVKYSDVELECEVTGTP 5909
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
++ W N + I +++ T++ + S + +HI + P G Y+C SN+ G S C
Sbjct: 5910 PFEVTWLKNNREIRSSKKYTLTDRVS-VFNLHITKCDPSDTGEYQCIVSNEGG--SCSCS 5966
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+ E P +K + T + ++ G P
Sbjct: 5967 TRVALKE----------------------PPSFIKKIENTTTVLKSSAT-FQSTVAGSPP 6003
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
+ WL+ ++L + D + L + V +G +A N GV A L
Sbjct: 6004 ISITWLKDD-QILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFL 6062
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
V+ E Q KA +SV V E++ +T E + +G
Sbjct: 6063 LVQ-----------------EPAQIVEKA-KSVD----------VTEKDPMTLECVVAGT 6094
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P ++ W KD K I F + + N + I+ K G YT K +D G + A
Sbjct: 6095 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 6154
Query: 1610 LQVFQR 1615
L+V +
Sbjct: 6155 LRVLDQ 6160
Score = 66.1 bits (154), Expect = 1e-09
Identities = 90/373 (24%), Positives = 142/373 (38%), Gaps = 64/373 (17%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM-DGERISLN 1302
+ K G TC+A N G S V+E P + LE + V GE I L
Sbjct: 7260 VGKGDSGQYTCQATNDVGKDMCSAQLSVKEP-------PKFVKKLEASKVAKQGESIQLE 7312
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CKI G P K+ WF N+ + + +S S + + I EA E +G Y C A N G
Sbjct: 7313 CKISGSPEIKVSWFRNDSELHESWKYNMSFINS-VALLTINEASAEDSGDYICEAHNGVG 7371
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEA 1422
S L ++ AP + P+ V +G + L+
Sbjct: 7372 DASCSTALTVK-------------------------APPVFTQKPSPVGALKGSDVILQC 7406
Query: 1423 KAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGV 1482
+ G P +V W++ ++ S +++I TS+ + + D GE +A N +G
Sbjct: 7407 EISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHIL-NLEASDVGEYHCKATNEVG- 7464
Query: 1483 TATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTF 1542
+ + SV+ +++P P FVK++ + V
Sbjct: 7465 -SDTCSCSVK-------FKEP-------------------PRFVKKLSDTSTLIGDAVEL 7497
Query: 1543 EAIYSGNPTPEILWYKDN-KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
AI G ++W KD +VIR E I +N T + G Y C+ +D
Sbjct: 7498 RAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDA 7557
Query: 1602 GLAVTKAKLQVFQ 1614
G+ A L V +
Sbjct: 7558 GMRECSAVLTVLE 7570
Score = 66.1 bits (154), Expect = 1e-09
Identities = 76/365 (20%), Positives = 147/365 (40%), Gaps = 57/365 (15%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G +C+A+N G+V++S +++E+ P L++ G ++ C+I G
Sbjct: 8014 VGEYSCKADNSVGAVASSAVLVIKERKL----PPFFARKLKDVHETLGFPVAFECRINGS 8069
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
++ W+ + L++ ++ S + + + I + G Y C+ASN G
Sbjct: 8070 EPLQVSWYKDGVLLKDDANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPLGTA---- 8124
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
S S + +LS+ + P P V G+ + G
Sbjct: 8125 -----------SSSAKLILSEHEV-------PPFFDLKPVSVDLALGESGTFKCHVTGTA 8166
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
++ W + E+ Y++ L + T+ LT+ +V + D G+ + Y
Sbjct: 8167 PIKITWAKDNREIRPGGNYKMT-LVENTATLTVLKVGKGDAGQ--YTCY----------- 8212
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER-VHEEEIVTFEAIYS 1547
+I G K H+ Q P F+K++ P R V ++E +E
Sbjct: 8213 --ASNIAG-----KDSCSAHL--------GVQEPPRFIKKLEPSRIVKQDEFTRYECKIG 8257
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G+P ++LWYKD I+ +F + ++ + + + G YTC+A + G A +
Sbjct: 8258 GSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSS 8317
Query: 1608 AKLQV 1612
L+V
Sbjct: 8318 TSLKV 8322
Score = 65.7 bits (153), Expect = 2e-09
Identities = 83/366 (22%), Positives = 136/366 (37%), Gaps = 56/366 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C EN +G S S ++ E P + LE V G+ SL C++ G P
Sbjct: 8863 GQYNCYIENASGKDSCSAQILILEP-------PYFVKQLEPVKVSVGDSASLQCQLAGTP 8915
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+ W+ + + + ++ + + + +G Y C A N G+ S
Sbjct: 8916 EIGVSWYKGDTKLRPTTTYKM-HFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTF 8974
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L ++ + PS S + DV+E LP V + G
Sbjct: 8975 LTVQEQKLPPSFSRQ-------LRDVQETV-----GLPVV----------FDCAISGSEP 9012
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
V W + G L S Q LD+ T+ L + + + G+ A N +G ++ A L
Sbjct: 9013 ISVSWYKDGKPLKDSPNVQTSFLDN-TATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ E + P P F + P E FE +G
Sbjct: 9072 ILT------EGKNP-------------------PFFDIRLAPVDAVVGESADFECHVTGT 9106
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
++ W KD++ IR+ ++ I EN T+ K K G YTC AV+++G A+
Sbjct: 9107 QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQ 9166
Query: 1610 LQVFQR 1615
L + +R
Sbjct: 9167 LNIKER 9172
Score = 64.5 bits (150), Expect = 4e-09
Identities = 76/359 (21%), Positives = 131/359 (36%), Gaps = 42/359 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
++N +++G ++ +CK+ G P PKI W+ + K I+ + + G + I P
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1356
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
E GIY ASN G L +E P + + + E S + +PR V P
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE--PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSP 1414
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL-------- 1459
++ R+ + + + G L ++ E Q+E L +L
Sbjct: 1415 IRMSPARMSPARMSPARMSPAR-----MSPGRRLEETDESQLERLYKPVFVLKPVSFKCL 1469
Query: 1460 --------------TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
MPE + G+ + Y H V S+ IV EW
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL-IIVPATPSDSGEW 1528
Query: 1506 VTHMEE----------LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEIL 1555
+ L Q P FV+++ + E + + +GNP P+I+
Sbjct: 1529 TVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIV 1588
Query: 1556 WYKDNKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
W K++ +I + + IE + I YT A++ G T+ K+ V
Sbjct: 1589 WLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 63.7 bits (148), Expect = 6e-09
Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 23/206 (11%)
Query: 1306 LGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
+G P ++W H+ K +E A + + + G C + A+ +GI C A+N++G
Sbjct: 1729 IGDPTMVVEWLHDGKPLEAANRLRMINE-FGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 1366 TECIL-------------------NIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
T L ++ E + ++ E L+ T E+ P IV
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIV-LY 1846
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P V EG+ R + G P+P+V W G + +S +++ DG L + +
Sbjct: 1847 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKS 1904
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVE 1492
DTGE+ A N GV L ++
Sbjct: 1905 YDTGEVKVTAENPEGVIEHKVKLEIQ 1930
Score = 63.3 bits (147), Expect = 8e-09
Identities = 83/356 (23%), Positives = 134/356 (37%), Gaps = 48/356 (13%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
VL P+ + ++G+ + K++GRP P+ WFH+ + I + ++ G + I
Sbjct: 1460 VLKPV-SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV 1518
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
A P +G + A N+ G+ S IL +EA E+ + P V
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH-------------------QVKPMFV 1559
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTSILTMP 1462
+ L V EG + ++ +A G P P + WL+ ++ +I E G + L +
Sbjct: 1560 EKLKN-VNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1618
Query: 1463 EVYQDDTGEIVFEAYNHLGVTATIAALSVE-----------SIVGTQEYRKPEWVT---- 1507
D+ A N G T ++VE I+ YR E
Sbjct: 1619 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELE 1678
Query: 1508 --HM-------EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS--GNPTPEILW 1556
H+ EE K Q P F K++ R+ FE + G+PT + W
Sbjct: 1679 PLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEW 1738
Query: 1557 YKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D K + R + N+ + A G TC+A + G T A L V
Sbjct: 1739 LHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 62.9 bits (146), Expect = 1e-08
Identities = 59/214 (27%), Positives = 94/214 (43%), Gaps = 20/214 (9%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI- 1458
P++++ L V T GK R A G P+P++ W ++ E L ST ++ + L DG
Sbjct: 3239 PQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKE--EQLLSTGFKCKFLHDGQEYT 3295
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E + +D EA N GV T A+LSVE PE V+ +E+
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV---------PEVVSPDQEMPVY--- 3343
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P + + E + F+ SG ++ WY +K I+ F + E+
Sbjct: 3344 ---PPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3399
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A + EGTYT A + +G + A L +
Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 62.9 bits (146), Expect = 1e-08
Identities = 85/370 (22%), Positives = 137/370 (37%), Gaps = 56/370 (15%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N +K G +C EN AG G+ + T + P + LE G+ +SL
Sbjct: 6974 NSTKRDAGQYSCEIENEAGR-DVCGALV---STL---EPPYFVTELEPLEAAVGDSVSLQ 7026
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C++ G P + W+ + + + + + + + + +G Y C A N G
Sbjct: 7027 CQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLVFNKVNINDSGEYTCKAENSIG 7085
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEA 1422
S++ + I+ + PS + + D+E+ T G + L
Sbjct: 7086 TASSKTVFRIQERQLPPSFARQ-------LKDIEQ---------------TVGLPVTLTC 7123
Query: 1423 KAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGV 1482
+ G QV W R G LL+ E D + L + + +G+ A N LG
Sbjct: 7124 RLNGSAPIQVCWYRDGV-LLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGT 7182
Query: 1483 TATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTF 1542
++ A L+ R+P+ P F + + V E F
Sbjct: 7183 ASSSARLTA---------REPK----------------KSPFFDIKPVSIDVIAGESADF 7217
Query: 1543 EAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E +G I W KDNK IR + I N I K K G YTC+A +D+G
Sbjct: 7218 ECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG 7277
Query: 1603 LAVTKAKLQV 1612
+ A+L V
Sbjct: 7278 KDMCSAQLSV 7287
Score = 62.1 bits (144), Expect = 2e-08
Identities = 93/399 (23%), Positives = 148/399 (37%), Gaps = 59/399 (14%)
Query: 1214 KDSHIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEE 1273
KD ++I + S + + + L +LE I +C EN AG I E
Sbjct: 7889 KDEYLISQ-SERCSITMTEKSTILEILESTIED--YAQYSCLIENEAGQ------DICEA 7939
Query: 1274 QTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ 1333
+ + P + PLE+ + GE +L CK+ G P +I W+ + +A + +
Sbjct: 7940 LVSVL-EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKM-QF 7997
Query: 1334 KSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTS 1393
K+ + + I + G Y C A N G ++ +L I+ + P + K
Sbjct: 7998 KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFA-------RKLK 8050
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD 1453
DV E T G + E + G QV W + G L Q +
Sbjct: 8051 DVHE---------------TLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVH 8095
Query: 1454 DGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
+ + L + + Q G+ A N LG ++ A L + E+ P
Sbjct: 8096 N-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL------SEHEVP---------- 8138
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
P F + + + E TF+ +G +I W KDN+ IR + +
Sbjct: 8139 ---------PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL 8189
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
EN T T+ K K G YTC A + G A L V
Sbjct: 8190 VENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGV 8228
Score = 61.7 bits (143), Expect = 2e-08
Identities = 88/363 (24%), Positives = 140/363 (38%), Gaps = 59/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC AEN AGS ++ G IV+E I A L+ V G+ +L + G P
Sbjct: 4919 GKYTCLAENEAGSQTSVGELIVKEPAKIIERAELI-------QVTAGDPATLEYTVAGTP 4971
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
K W+ + + + ++ IS K+ + ++ A +G Y SN+ G S E
Sbjct: 4972 ELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 5030
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+V + D+ AP K L V + G RL+ K G
Sbjct: 5031 F---------TVLDRDI------------APFFTKPLRNVDSVVNGTC-RLDCKIAGSLP 5068
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
+V W + G E+ S Y+I + +GT+ L + V +D G A N +G + AL
Sbjct: 5069 MRVSWFKDGKEIAASDRYRIAFV-EGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 5127
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
V+ P +VT K+++P V ++ + G+
Sbjct: 5128 IVQ--------EPPSFVTKPGS---------------KDVLP-----GSAVCLKSTFQGS 5159
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
I W+K NK + + I + ++ + GTYTCK + G A
Sbjct: 5160 TPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSAN 5219
Query: 1610 LQV 1612
L V
Sbjct: 5220 LFV 5222
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/380 (24%), Positives = 143/380 (37%), Gaps = 66/380 (17%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD- 1295
LN+ + SK G TC N GS S + +V E P + LE + ++
Sbjct: 6314 LNLYSVDASKT--GQYTCHVTNDVGSDSCTTMLLVTEP-------PKFVKKLEASKIVKA 6364
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G+ L CKI G P ++ WF NE + + ++ S + I + E +G + C
Sbjct: 6365 GDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDS-VAVIQMNNLSTEDSGDFIC 6423
Query: 1356 TASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEG 1415
A N G ST C + E P + + P +V T +
Sbjct: 6424 EAQNPAG--STSCSTKVIVKE-----------------------PPVFSSFPPIVETLKN 6458
Query: 1416 KLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFE 1475
+ LE + G P +V W + +L S +Y+I + TSI + V D GE +
Sbjct: 6459 AEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHIL-NVDTSDIGEYHCK 6517
Query: 1476 AYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVH 1535
A N +G ++ V T + ++P P FV ++ V
Sbjct: 6518 AQNEVG---------SDTCVCTVKLKEP-------------------PRFVSKLNSLTVV 6549
Query: 1536 EEEIVTFEAIYSGNPTPEILWYKD-NKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
E +A G + W K+ +VIR E I EN T KA G Y
Sbjct: 6550 AGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYI 6609
Query: 1595 CKAVSDIGLAVTKAKLQVFQ 1614
C+ +D G+ A L V +
Sbjct: 6610 CQIKNDGGMEENMATLMVLE 6629
Score = 60.5 bits (140), Expect = 6e-08
Identities = 86/378 (22%), Positives = 142/378 (37%), Gaps = 62/378 (16%)
Query: 1239 VLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGE 1297
VLE N+S + G TC A N AGS S+S S V+E P+ + G
Sbjct: 8289 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE-------PPIFRKKPHPIETLKGA 8341
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L C++ G P + W+ +++ + + + I ++ L IHI G Y+C A
Sbjct: 8342 DVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIHILNVDAADIGEYQCKA 8400
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
+N G S C+ +I + PR VK L + ++T GK
Sbjct: 8401 TNDVG--SDTCVGSIAL----------------------KAPPRFVKKL-SDISTVVGKE 8435
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
++L+ G V W + E+++ ++ + + L V + G+ +
Sbjct: 8436 VQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIK 8495
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
N G+ A LSV E KPE ++K T
Sbjct: 8496 NDAGMQECFATLSVLEPATIVE--KPE----------SIKVTTG---------------- 8527
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
+ T E +G P W+KD K + +D ++ I + I G Y+ +
Sbjct: 8528 DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEV 8587
Query: 1598 VSDIGLAVTKAKLQVFQR 1615
+ +G A LQV R
Sbjct: 8588 QNPVGKDSCTASLQVSDR 8605
Score = 60.1 bits (139), Expect = 8e-08
Identities = 64/276 (23%), Positives = 114/276 (41%), Gaps = 34/276 (12%)
Query: 1218 IIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
++ KD L + + L +L+ + S IG C A N G+ S+S I+ E
Sbjct: 8081 VLLKDDANLQTSFVHNVATLQILQTDQSH--IGQYNCSASNPLGTASSSAKLILSEHEV- 8137
Query: 1278 DGDAPLV-LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
P L P+ + GE + C + G KI W + + I + ++ ++
Sbjct: 8138 ---PPFFDLKPVSVDLAL-GESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENT 8193
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+K + AG Y C ASN GK S L ++
Sbjct: 8194 ATLTVLKVGKGD-AGQYTCYASNIAGKDSCSAHLGVQE---------------------- 8230
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
PR +K L + + R E K G P+ +V W + TE+ +S+++++ + D
Sbjct: 8231 --PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFV-DSV 8287
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
++L M + +D+G+ EA+N G ++ +L V+
Sbjct: 8288 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 8323
Score = 60.1 bits (139), Expect = 8e-08
Identities = 86/365 (23%), Positives = 134/365 (36%), Gaps = 63/365 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC+ +N AG + V E A +V P E+ V G+ +L C + G P
Sbjct: 8488 GKYTCQIKNDAGMQECFATLSVLEP------ATIVEKP-ESIKVTTGDTCTLECTVAGTP 8540
Query: 1310 WPKIDWFHNEKLIETARDITIS--RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
WF + K + + IS + SGL I++ P +G+Y N GK S
Sbjct: 8541 ELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVA---PSDSGVYSFEVQNPVGKDSCT 8597
Query: 1368 CILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L + PS T ++E G + +E K G
Sbjct: 8598 ASLQVSDRTVPPSF----------TRKLKE------------TNGLSGSSVVMECKVYGS 8635
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P V W +G E+ +YQ L D T LT+ + + D+G+ A N G A
Sbjct: 8636 PPISVSWFHEGNEISSGRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSA 8694
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
L+V R+P P+FV++ P V VTF +I
Sbjct: 8695 PLTV---------REP-------------------PSFVQKPDPMDVLTGTNVTFTSIVK 8726
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P + W+K + + +R + +++ + G YTC ++ G A
Sbjct: 8727 GTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCT 8786
Query: 1608 AKLQV 1612
L +
Sbjct: 8787 THLYI 8791
Score = 59.7 bits (138), Expect = 1e-07
Identities = 80/366 (21%), Positives = 141/366 (38%), Gaps = 62/366 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C A N GS S S +++E P + LE ++ G L C++ G
Sbjct: 4733 GSYSCEAVNDVGSDSCSTEIVIKEP-------PSFIKTLEPADIVRGTNALLQCEVSGTG 4785
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+I WF ++K I +++ + QKS +C + I G Y+C +N+ GKC C+
Sbjct: 4786 PFEISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYECVVANEVGKCG--CM 4842
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
T ++E P VK + ++ G+ + L+A G
Sbjct: 4843 ---------------------ATHLLKE-PPTFVKKVDDLI-ALGGQTVTLQAAVRGSEP 4879
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
V W++ G E+++ +G ++L +P+V G+ A N G ++ L
Sbjct: 4880 ISVTWMK-GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGEL 4938
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
V ++P + EL ++ T P T E +G
Sbjct: 4939 IV---------KEPAKIIERAEL---IQVTAGDP----------------ATLEYTVAGT 4970
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P + WYKD + + +++ I K N A G YT + +++G + +
Sbjct: 4971 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 5030
Query: 1610 LQVFQR 1615
V R
Sbjct: 5031 FTVLDR 5036
Score = 58.8 bits (136), Expect = 2e-07
Identities = 75/346 (21%), Positives = 131/346 (37%), Gaps = 61/346 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG SG V+E P + ++ V R+ L + G
Sbjct: 5670 GTYTCSATNKAGHNQCSGHLTVKEP-------PYFVEKPQSQDVNPNTRVQLKALVGGTA 5722
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
I WF + K + + ++ + + + + A +G Y C SN G +++
Sbjct: 5723 PMTIKWFKDNKELHSGAARSVWKDDTST-SLELFAAKATDSGTYICQLSNDVGTATSKAT 5781
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L ++ P+ +K V+ G+ E + G PK
Sbjct: 5782 LFVKE------------------------PPQFIKKPSPVLVLRNGQSTTFECQITGTPK 5817
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
+V W G E+ ++ I +D G + + +++G V EA N G A+
Sbjct: 5818 IRVSWYLDGNEITAIQKHGISFID-GLATFQISGARVENSGTYVCEARNDAGT----ASC 5872
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
S+E V ++P PTF++E+ P V + V E +G
Sbjct: 5873 SIELKV-----KEP-------------------PTFIRELKPVEVVKYSDVELECEVTGT 5908
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTC 1595
P E+ W K+N+ IR+ +++ + ++ + I K G Y C
Sbjct: 5909 PPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC 5954
Score = 58.4 bits (135), Expect = 2e-07
Identities = 74/360 (20%), Positives = 140/360 (38%), Gaps = 54/360 (15%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTS-GSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
+S ++ V A + V+ GSSI + + + P + +E+T+ + G +
Sbjct: 5375 VSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLR-EPPSFIKKIESTSSLRGGTAAFQ 5433
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
+ G + W + I +I ++ + + + +++ + G Y C A N G
Sbjct: 5434 ATLKGSLPITVTWLKDSDEITEDDNIRMTFENN-VASLYLSGIEVKHDGKYVCQAKNDAG 5492
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEA 1422
I+ + SV E +++E S + T+G L+
Sbjct: 5493 ---------IQRCSALLSVKEPATITEEAVS----------------IDVTQGDPATLQV 5527
Query: 1423 KAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGV 1482
K G + +W + G EL ++Y+I + D SIL + + D+GE FE N +G
Sbjct: 5528 KFSGTKEITAKWFKDGQELTLGSKYKI-SVTDTVSILKIISTEKKDSGEYTFEVQNDVGR 5586
Query: 1483 TATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTF 1542
++ A ++V ++ + K LK S+ + +
Sbjct: 5587 SSCKARINVLDLIIPPSFTK------------KLKKMDSI-------------KGSFIDL 5621
Query: 1543 EAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E I +G+ I W+KD++ I E++ +N I + GTYTC A + G
Sbjct: 5622 ECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 5681
Score = 58.0 bits (134), Expect = 3e-07
Identities = 72/339 (21%), Positives = 126/339 (37%), Gaps = 52/339 (15%)
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I D P++ PL +T +G+ + L I +++W+ KL+ + + ++
Sbjct: 4284 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNT 4341
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ K + G Y C A N GK +T L + V+
Sbjct: 4342 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV----------------------VK 4379
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
AP ++K + G L + + P + +W + G E+ +S + I
Sbjct: 4380 RAAP-VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS-SKYI 4437
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAAL 1516
S L + D GE +A N G + A L+V T+ Y P + L
Sbjct: 4438 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-----TEAY-PPTF----------L 4481
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKEN 1576
+S+ TFV + F +G P E +W KD + + I + EN
Sbjct: 4482 SRPKSLTTFVGKA----------AKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAEN 4531
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + T G Y+CKA + G + +A+L + +
Sbjct: 4532 KHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK 4570
Score = 57.6 bits (133), Expect = 4e-07
Identities = 80/382 (20%), Positives = 150/382 (39%), Gaps = 63/382 (16%)
Query: 1222 DSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA 1281
+S + + R + + +L +L + G TC+A N GSVS + + V E
Sbjct: 4425 ESDKCSIRSSKYISSLEILRTQVVD--CGEYTCKASNEYGSVSCTATLTVTEAY-----P 4477
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L+ ++ T G+ C + G P + W + + + + IS ++ +
Sbjct: 4478 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHI-LE 4536
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
+ + G+Y C ASN+FG + + +++ +K ++E P
Sbjct: 4537 LSNLTIQDRGVYSCKASNKFG----------------ADICQAELIIIDKPHFIKELEP- 4579
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM 1461
V + K + LE + K V W + G +L +Y+I +D + L +
Sbjct: 4580 --------VQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKI-CFEDKIATLEI 4630
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
P D+G V A N G ++ A ++V R+P
Sbjct: 4631 PLAKLKDSGTYVCTASNEAGSSSCSATVTV---------REP------------------ 4663
Query: 1522 VPTFVKEIIPERVH-EEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P+FVK++ P + E G+P ++ W+K+NK + + +
Sbjct: 4664 -PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAIL 4722
Query: 1581 TIKKATKDLEGTYTCKAVSDIG 1602
I + G+Y+C+AV+D+G
Sbjct: 4723 DITDVKVEDSGSYSCEAVNDVG 4744
Score = 57.6 bits (133), Expect = 4e-07
Identities = 86/364 (23%), Positives = 144/364 (39%), Gaps = 65/364 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C N AGS S + V+E + L + +V G I L G P
Sbjct: 7829 GDYSCLVTNDAGSASCTTHLFVKEPATF-------VKRLADFSVETGSPIVLEATYTGTP 7881
Query: 1310 WPKIDWFHNEKLIETARDITIS-RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+ W +E LI + +I+ +KS + E I E+ E Y C N+ G+ E
Sbjct: 7882 PISVSWIKDEYLISQSERCSITMTEKSTILE--ILESTIEDYAQYSCLIENEAGQDICEA 7939
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ SV E P ++ L V G+ L+ K G P
Sbjct: 7940 LV---------SVLE---------------PPYFIEPLEHVEAVI-GEPATLQCKVDGTP 7974
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
+ ++ W ++ T+L + Y++ + + + L + +V D GE +A N +G A+ A
Sbjct: 7975 EIRISWYKEHTKLRSAPAYKM-QFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAV 8033
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE--EIVTFEAIY 1546
L + +E + P P F +++ + VHE V FE
Sbjct: 8034 LVI------KERKLP-------------------PFFARKL--KDVHETLGFPVAFECRI 8066
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
+G+ ++ WYKD +++ D N T I + + G Y C A + +G A +
Sbjct: 8067 NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASS 8126
Query: 1607 KAKL 1610
AKL
Sbjct: 8127 SAKL 8130
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 56.0 bits (129), Expect = 1e-06
Identities = 76/333 (22%), Positives = 127/333 (38%), Gaps = 55/333 (16%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + L++ + G + L C++ G + WF + I + S ++ +C ++
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCTLN 7726
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
+ P GIY C A+N G S EC V +V E S E+T D E P
Sbjct: 7727 LSLLEPSDTGIYTCVAANVAG--SDEC-------SAVLTVQEPP--SFEQTPDSVEVLPG 7775
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM 1461
+ +V+ G P +V+W + EL+ I L+D + L +
Sbjct: 7776 MSLTFTSVIR--------------GTPPFKVKWFKGSRELVPGESCNIS-LEDFVTELEL 7820
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
EV ++G+ S + T + TH+ + A
Sbjct: 7821 FEVQPLESGDY--------------------SCLVTNDAGSASCTTHLFVKEPA------ 7854
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
TFVK + V + EA Y+G P + W KD +I ER I E T
Sbjct: 7855 --TFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILE 7912
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
I ++T + Y+C ++ G + +A + V +
Sbjct: 7913 ILESTIEDYAQYSCLIENEAGQDICEALVSVLE 7945
Score = 55.6 bits (128), Expect = 2e-06
Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
P+ Y+ + G E +GV+ T + E + + VT + A ++ +
Sbjct: 887 PDTYKSEAG---VEVKKEVGVSITGTTVREERFEVL--HGREAKVTETARVPAPVEIPVT 941
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT V + V E E VT E SG P+P + WY+++ I + F I +
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++A + G +TC AV++ G T L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 55.6 bits (128), Expect = 2e-06
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 10/132 (7%)
Query: 1492 ESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP-------ERVHEEEIVTFEA 1544
ES+ ++E + + EE+ A +K ++ F+KE P + V EE +
Sbjct: 4251 ESLKPSEEKEESSSESGTEEV-ATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLT 4309
Query: 1545 IYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKA-TKDLEGTYTCKAVSDIGL 1603
N E+ WY +NK++ +DE+F +N T I K T+D +G Y C+A++D G
Sbjct: 4310 TSITN-AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGK 4368
Query: 1604 AVTKAKLQVFQR 1615
T AKL V +R
Sbjct: 4369 TATSAKLTVVKR 4380
Score = 55.2 bits (127), Expect = 2e-06
Identities = 83/375 (22%), Positives = 139/375 (37%), Gaps = 60/375 (16%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
V+++ ++D G C A N +G +TS V ++ AP++ +E V G
Sbjct: 4345 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA-----APVIKRKIEPLEVALGHL 4399
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
C+I P + WF + I + +I R + + I G Y C AS
Sbjct: 4400 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 4458
Query: 1359 NQFGKCSTECILNI-EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
N++G S L + EAY P + P +TT GK
Sbjct: 4459 NEYGSVSCTATLTVTEAY------------------------PPTFLSRPKSLTTFVGKA 4494
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
+ G P + W + G L S ++I + ++ IL + + D G +A
Sbjct: 4495 AKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAEN-KHILELSNLTIQDRGVYSCKAS 4553
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
N G A L + KP ++ +E +Q+A+ K + +V E+
Sbjct: 4554 NKFGADICQAELII--------IDKPHFIKELEPVQSAINK--------KVHLECQVDED 4597
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
VT + W KD + + + + I ++ T I A GTY C A
Sbjct: 4598 RKVT------------VTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTA 4645
Query: 1598 VSDIGLAVTKAKLQV 1612
++ G + A + V
Sbjct: 4646 SNEAGSSSCSATVTV 4660
Score = 54.8 bits (126), Expect = 3e-06
Identities = 72/321 (22%), Positives = 120/321 (37%), Gaps = 52/321 (16%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV GE +L CK+ G P ++W+ + KL+ +++ S + + I + AG
Sbjct: 6641 TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK-ISSLRILSVERQDAG 6699
Query: 1352 IYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVT 1411
Y N GK S ++++ PS + R +K V+
Sbjct: 6700 TYTFQVQNNVGKSSCTAVVDVSDRAVPPSFT------------------RRLKNTGGVL- 6740
Query: 1412 TTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE 1471
G LE K G V W + T+++ +YQ D L + + D G
Sbjct: 6741 ---GASCILECKVAGSSPISVAWFHEKTKIVSGAKYQ-TTFSDNVCTLQLNSLDSSDMG- 6795
Query: 1472 IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP 1531
N+ V A +A G+ E R A+ Q P+FVKE P
Sbjct: 6796 ------NYTCVAANVA--------GSDECR-------------AVLTVQEPPSFVKEPEP 6828
Query: 1532 ERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V + VTF ++ G P ++ W++ + + +R I ++ + G
Sbjct: 6829 LEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSG 6888
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
YTC ++ G A +L V
Sbjct: 6889 EYTCVVSNNAGQASCTTRLFV 6909
Score = 54.8 bits (126), Expect = 3e-06
Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMD---GERISLNCKILGRPWP 1311
A N GS+S S +V TCID P++ PLE T V+ G + L I G+P P
Sbjct: 27771 ARNAVGSISNP-SEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAP 27829
Query: 1312 KIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
I+W+ ++K ++T + + + L I IK+A +G Y+ N G S
Sbjct: 27830 TIEWYKDDKELQTNALVCV-ENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 27882
Score = 54.0 bits (124), Expect = 5e-06
Identities = 62/258 (24%), Positives = 110/258 (42%), Gaps = 38/258 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TCRA N GS +SG+ IV+E P + + V+ G + L G
Sbjct: 5108 GNFTCRATNSVGSKDSSGALIVQE-------PPSFVTKPGSKDVLPGSAVCLKSTFQGST 5160
Query: 1310 WPKIDWFHNEKLIETARDITISRQK-SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
I WF K + + I+++ E+++ + +G Y C SN G EC
Sbjct: 5161 PLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKT--SDSGTYTCKVSNVAG--GVEC 5216
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP-RIVKALPTVVTTTEGKLIRLEAKAIGI 1427
N+ E + VE+ P +++K +G +L K G
Sbjct: 5217 SANL--------------FVKEPATFVEKLEPSQLLK---------KGDATQLACKVTGT 5253
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P ++ W E+ +S+++++ + + T++L + +V +D+GE + EA N G +
Sbjct: 5254 PPIKITWFANDREIKESSKHRMSFV-ESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSS 5312
Query: 1488 ALSV-ESIVGTQEYRKPE 1504
+ V ES T+E++ E
Sbjct: 5313 IVIVKESPYFTKEFKPIE 5330
Score = 53.6 bits (123), Expect = 7e-06
Identities = 75/338 (22%), Positives = 135/338 (39%), Gaps = 20/338 (5%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
+VL P E V++GE C++ G P PK++W+ N +LI ++ + + G+ + I
Sbjct: 1843 IVLYP-EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLDI 1899
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR- 1401
+ G K TA N G + L I+ E SV + E + P
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRR---APEPRPEFHVHEPGK 1956
Query: 1402 ---IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE-LDDGTS 1457
V+ + V TTE K + +A I +V + EL + + EE + +
Sbjct: 1957 LQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVP--EESEELRSKFKRRTEEGYYEAIT 2014
Query: 1458 ILTMPEVYQDDTGEIVFEAYNH--LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ + +D++ E + L T + +++ + P + EL +
Sbjct: 2015 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2074
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN-KVIRTDERFIIENK 1574
++A P + I + V + F G P PE WYK+ K+ R+D + +
Sbjct: 2075 MEA----PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+N I+ T + + KA++ G + A L V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2168
Score = 53.2 bits (122), Expect = 9e-06
Identities = 79/389 (20%), Positives = 145/389 (37%), Gaps = 62/389 (15%)
Query: 1214 KDSHIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEE 1273
KD I+++D + + L + ++ G TC+A+N +G +V+E
Sbjct: 6010 KDDQILDEDDNVYIS-FVDSVATLQI--RSVDNGHSGRYTCQAKNESGVERCYAFLLVQE 6066
Query: 1274 QTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ 1333
I A ++ V + + ++L C + G P K+ W + K I +R ++S +
Sbjct: 6067 PAQIVEKA-------KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFE 6119
Query: 1334 KSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTS 1393
+ + I+ + +G Y N FG S + L + PS
Sbjct: 6120 -NNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPS------------- 6165
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD 1453
F ++ K + G I +E K G +W + G E+ S +Y++ +
Sbjct: 6166 ----FTKKLTK-----MDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHE 6216
Query: 1454 DGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
S L + + +DT + N G A L+V+ P ++ Q
Sbjct: 6217 RSVS-LEVNNLELEDTANYTCKVSNVAGDDACSGILTVK--------EPPSFLVKPGRQQ 6267
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A IP + V F+AI G P +I W+KD+ + + + I
Sbjct: 6268 A---------------IP-----DSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL 6307
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ + + + G YTC +D+G
Sbjct: 6308 EGSTSFLNLYSVDASKTGQYTCHVTNDVG 6336
Score = 52.8 bits (121), Expect = 1e-05
Identities = 85/367 (23%), Positives = 133/367 (36%), Gaps = 62/367 (16%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G TC A N AGS V+E P + E V+ G+ ++ I G
Sbjct: 6794 MGNYTCVAANVAGSDECRAVLTVQEP-------PSFVKEPEPLEVLPGKNVTFTSVIRGT 6846
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P K++WF + + I + + + E+ + +G Y C SN G+ S C
Sbjct: 6847 PPFKVNWFRGARELVKGDRCNIYFEDT-VAELELFNIDISQSGEYTCVVSNNAGQAS--C 6903
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
+ E + LSD + GK I LE+ G
Sbjct: 6904 TTRLFVKEPAAFLKR---LSDH--------------------SVEPGKSIILESTYTGTL 6940
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
V W + G + S + I + T IL + + D G+ E N G A
Sbjct: 6941 PISVTWKKDGFNITTSEKCNIVTTEK-TCILEILNSTKRDAGQYSCEIENEAGRDVCGA- 6998
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
+V T E P +VT +E L+AA+ + V+ + +G
Sbjct: 6999 -----LVSTLE--PPYFVTELEPLEAAV--------------------GDSVSLQCQVAG 7031
Query: 1549 NPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P + WYK + +R + N T K + G YTCKA + IG A +K
Sbjct: 7032 TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT 7091
Query: 1609 KLQVFQR 1615
++ +R
Sbjct: 7092 VFRIQER 7098
Score = 52.4 bits (120), Expect = 2e-05
Identities = 39/141 (27%), Positives = 64/141 (45%), Gaps = 12/141 (8%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM-DGERISLNCKILGR 1308
G C A N AGS S S + V E P + ++ + +M GE L+CK+ G
Sbjct: 4639 GTYVCTASNEAGSSSCSATVTVREP-------PSFVKKVDPSYLMLPGESARLHCKLKGS 4691
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG--KCST 1366
P ++ WF N K + + + + S + I + E +G Y C A N G CST
Sbjct: 4692 PVIQVTWFKNNKELSESNTVRMYFVNSEAI-LDITDVKVEDSGSYSCEAVNDVGSDSCST 4750
Query: 1367 ECILNIEAYEYVPSVSEEDVL 1387
E ++ E ++ ++ D++
Sbjct: 4751 EIVIK-EPPSFIKTLEPADIV 4770
Score = 51.6 bits (118), Expect = 3e-05
Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 5/109 (4%)
Query: 1510 EELQAALKATQSVPTF---VKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD 1566
EE+QA TQ P VK + V + A +G P P+I W K + +++ D
Sbjct: 14604 EEIQAV--DTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQD 14661
Query: 1567 ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+R IEN ++T TI + + GTY +AV+ G A ++ V +
Sbjct: 14662 KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 14710
Score = 51.2 bits (117), Expect = 4e-05
Identities = 64/250 (25%), Positives = 105/250 (42%), Gaps = 35/250 (14%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ IG C+A+N GS + + ++E P ++ L + TV+ GE L
Sbjct: 6505 NVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP-------PRFVSKLNSLTVVAGEPAELQ 6557
Query: 1303 CKILGRPWPKIDWF-HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
I G + W E++I + +I I+ ++ + + +A P AG Y C N
Sbjct: 6558 ASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATLQFAKAEPANAGKYICQIKNDG 6616
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G EE++ T V E A + KA P +T T G+ LE
Sbjct: 6617 GM-------------------EENMA----TLMVLEPAVIVEKAGP--MTVTVGETCTLE 6651
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K G P+ V W + G +LL S++ + S L + V + D G F+ N++G
Sbjct: 6652 CKVAGTPELSVEWYKDG-KLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVG 6710
Query: 1482 VTATIAALSV 1491
++ A + V
Sbjct: 6711 KSSCTAVVDV 6720
Score = 50.8 bits (116), Expect = 5e-05
Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + +++ TV G +++G+P P+ +W+ N IE + I + +CE
Sbjct: 2076 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE-EDVLSDEK 1391
+ I++ E + A N G+ S+ L ++A + + E +DV++ EK
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEK 2188
Score = 50.8 bits (116), Expect = 5e-05
Identities = 25/88 (28%), Positives = 45/88 (51%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F KE P V +E V A +G P EI W+KDN ++R+ ++ +++ + I
Sbjct: 5320 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI 5379
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
K G Y C+ +++G ++ A++
Sbjct: 5380 LKFVAADAGEYQCRVTNEVGSSICSARV 5407
Score = 50.0 bits (114), Expect = 8e-05
Identities = 95/493 (19%), Positives = 186/493 (37%), Gaps = 30/493 (6%)
Query: 36 DHKTQIQSTSTKKVEPTTGKASYSTT-EETNMLKVENIQDTETKNITTVPWRKREQLDMH 94
+ K + KK P + S T EE + E + + + + +
Sbjct: 10364 EEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWS 10423
Query: 95 FKKEDT-LEIKHWRRSRPEQNKDTEHTS--MIGXXXXXXXXXXXXVFERGVIEEHVKVQE 151
+ +E+ + I +R E+ ++ E T ++ + + V E +V E
Sbjct: 10424 YSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTE 10483
Query: 152 VVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEE 211
E K+ KPK ++ ++ E + E V K E P++ E
Sbjct: 10484 RQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEK----KVPAPVPKKEKVP--PPKVPE 10537
Query: 212 SLEEVGPTKGVNEPEVCHWRKPKTSEI----LKDKNEEEIRVQEMKKQSTKALEVKDESK 267
++ P K V P+V +P +++ ++ EE++ V KK++ V +E K
Sbjct: 10538 EPKKPVPEKKV-PPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPK 10596
Query: 268 QKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNERQITEK 327
+ +P ++ +KL+P + E+ P K+ + + V+++ + E + E I E+
Sbjct: 10597 RAVP-EEKVLKLKPKREEEPP---AKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEE 10652
Query: 328 KESLQ--ETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXX 385
KE E + ++ + E + KE E +E +
Sbjct: 10653 KERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEY 10712
Query: 386 XXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAI----KLRPTKMEKTPIEKE 441
PV +E T+ + K ++P + + KL+P K P E +
Sbjct: 10713 ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP-PKVPEEPK 10771
Query: 442 K-FED-ITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGK 499
K FE+ I + T+++ +++TE + + EE P E P +
Sbjct: 10772 KVFEEKIRISITKREK--EQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 10829
Query: 500 RQPKEETPQEEVV 512
+P+E +EEVV
Sbjct: 10830 LEPEEVAFEEEVV 10842
Score = 49.6 bits (113), Expect = 1e-04
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 1510 EELQAALKATQSVPT-FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER 1568
E++ + +++V + F I R+ E VTF SG P P+I WYKD K I+ ER
Sbjct: 1277 EKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1336
Query: 1569 FIIE-NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ ++ R + I + EG YT A + G A+ KL V
Sbjct: 1337 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381
Score = 49.6 bits (113), Expect = 1e-04
Identities = 43/113 (38%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDG-DAP-LVLAPL--ENTTVMDGERISLNC-KILGRP 1309
RA+N AG++S S E C D +AP +VL P + T+ G+ I LN ILG+P
Sbjct: 21276 RAKNTAGAISAPSES-TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKP 21334
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
PK W K I + DIT + IK A + AG Y TA+N FG
Sbjct: 21335 LPKSSWSKAGKDIRPS-DITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 21386
Score = 48.4 bits (110), Expect = 2e-04
Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 17/206 (8%)
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
IG P V WL G L + ++ + G L Y D+G I A N G
Sbjct: 1729 IGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 1485 TIAALSVESIVG-TQEYRKPEW---VTHMEELQ--AALKATQSVPTFVKE-------IIP 1531
T A L V+ +E + PE + +EEL+ A A V T KE + P
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1847
Query: 1532 E--RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
E RV E E F +G P P++ WY + ++IR +RF + + + D
Sbjct: 1848 EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYD- 1906
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQVFQR 1615
G A + G+ K KL++ QR
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQR 1932
Score = 48.0 bits (109), Expect = 3e-04
Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 8/153 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLENTTVMDGERISLNCKILGR 1308
G T A+N AG S S VE ++ P+ + L+N + +G ++ + + G
Sbjct: 1526 GEWTVVAQNRAGRSSISVILTVE---AVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGN 1582
Query: 1309 PWPKIDWFHNEKLIETAR--DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P P I W N +I + I I K G + I + + Y TA N+ G+ +T
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTK-GEAALKIDSTVSQDSAWYTATAINKAGRDTT 1641
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
C +N+E E+ E ++ T +E A
Sbjct: 1642 RCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIA 1673
Score = 48.0 bits (109), Expect = 3e-04
Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 37/268 (13%)
Query: 1218 IIEKDSTELTPRI---IQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEE 1273
I +KD L+P I + ++LE N++ GV +C+A N G+ I +
Sbjct: 4510 IWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASN------KFGADICQA 4563
Query: 1274 QTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ 1333
+ I D P + LE +++ L C++ + W + + + +D I +
Sbjct: 4564 ELIII-DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFE 4622
Query: 1334 KSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTS 1393
+ + I A + +G Y CTASN+ G S+ C + E
Sbjct: 4623 DK-IATLEIPLAKLKDSGTYVCTASNEAG--SSSCSATVTVRE----------------- 4662
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD 1453
P VK + G+ RL K G P QV W + EL +S ++ +
Sbjct: 4663 -----PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFV- 4716
Query: 1454 DGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ +IL + +V +D+G EA N +G
Sbjct: 4717 NSEAILDITDVKVEDSGSYSCEAVNDVG 4744
Score = 48.0 bits (109), Expect = 3e-04
Identities = 42/165 (25%), Positives = 64/165 (38%), Gaps = 9/165 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N++ GV + +N G S + S V ++T P L+ T + G + +
Sbjct: 8574 NVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTV----PPSFTRKLKETNGLSGSSVVME 8629
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CK+ G P + WFH I + R + C + + +G Y C A+N G
Sbjct: 8630 CKVYGSPPISVSWFHEGNEISSGRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIATNMAG 8688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
S EC + E V + D + D T F IVK P
Sbjct: 8689 --SDECSAPLTVREPPSFVQKPDPM-DVLTGTNVTFT-SIVKGTP 8729
Score = 47.6 bits (108), Expect = 4e-04
Identities = 78/366 (21%), Positives = 134/366 (36%), Gaps = 66/366 (18%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDG 1296
+N+LEE+ S D TC A N AGS S V E P + + V+ G
Sbjct: 8668 VNMLEESDSGDY----TCIATNMAGSDECSAPLTVREP-------PSFVQKPDPMDVLTG 8716
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCT 1356
++ + G P + WF + +S + S + E+ + + +G Y C
Sbjct: 8717 TNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDS-VAELELFDVDTSQSGEYTCI 8775
Query: 1357 ASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGK 1416
SN+ GK S L I+A P+ + VK L + +GK
Sbjct: 8776 VSNEAGKASCTTHLYIKA----PA--------------------KFVKRL-NDYSIEKGK 8810
Query: 1417 LIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEA 1476
+ LE G P V W + G + S I + ++IL +P +D G+
Sbjct: 8811 PLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK-SAILEIPSSTVEDAGQYNCYI 8869
Query: 1477 YNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHE 1536
N G + A + + P +V +E ++ ++ + S+
Sbjct: 8870 ENASGKDSCSAQILI--------LEPPYFVKQLEPVKVSVGDSASL-------------- 8907
Query: 1537 EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
+ +G P + WYK + +R + + + N T + + G Y CK
Sbjct: 8908 ------QCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICK 8961
Query: 1597 AVSDIG 1602
A + +G
Sbjct: 8962 AENSVG 8967
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/70 (31%), Positives = 35/70 (50%)
Query: 1546 YSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAV 1605
+ G PTP + W+KDN ++ R E+ EN + TIK A ++ G Y K + G A+
Sbjct: 23098 FIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAI 23157
Query: 1606 TKAKLQVFQR 1615
+ V +
Sbjct: 23158 ETLNVIVLDK 23167
Score = 47.2 bits (107), Expect = 6e-04
Identities = 26/90 (28%), Positives = 43/90 (47%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P FV++ + V+ V +A+ G I W+KDNK + + + + T+ +
Sbjct: 5695 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLEL 5754
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
A GTY C+ +D+G A +KA L V
Sbjct: 5755 FAAKATDSGTYICQLSNDVGTATSKATLFV 5784
Score = 47.2 bits (107), Expect = 6e-04
Identities = 26/106 (24%), Positives = 48/106 (45%)
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
+++ AL + P F++ + E T + G P I WYK++ +R+ +
Sbjct: 7934 QDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAY 7993
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
++ K N + I K G Y+CKA + +G + A L + +R
Sbjct: 7994 KMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER 8039
Score = 47.2 bits (107), Expect = 6e-04
Identities = 24/76 (31%), Positives = 38/76 (50%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V A SG P P I WYKD+K ++T+ +EN + + IK A + G Y K +
Sbjct: 27817 VKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 27876
Query: 1600 DIGLAVTKAKLQVFQR 1615
+G A ++Q+ +
Sbjct: 27877 AMGSASATIRVQILDK 27892
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/151 (25%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 1263 VSTSGSSIVEEQTCI-DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
V + +S+ EEQ + AP + +++G + C++ G P P + W +
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121
Query: 1322 IETARDITISRQK-SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA-YEYVP 1379
+ T +S K +G C++ I F + AG Y N+ G+ S L EA YE +
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1181
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
+E + + T+ V+E P++ + P V
Sbjct: 1182 KSQQEMLYQTQVTAFVQE--PKVGETAPGFV 1210
Score = 46.4 bits (105), Expect = 0.001
Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
Query: 1514 AALKATQSV---PTFVKEIIPERV-HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
A KAT V P F+K+ P V + TFE +G P + WY D I ++
Sbjct: 5776 ATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKH 5835
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I + T I A + GTY C+A +D G A +L+V
Sbjct: 5836 GISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKV 5878
Score = 46.4 bits (105), Expect = 0.001
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++E IG P+P + W++ G L Q+T +EE T +L + E +DD G+
Sbjct: 25253 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST-VLHIKEGNKDDFGKYTV 25311
Query: 1475 EAYNHLGVTAT 1485
A N G TAT
Sbjct: 25312 TATNSAG-TAT 25321
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV-----KALPTVVTTTEGKLIRLEAKAIGI 1427
E Y + S E +SD + V A +V K L T G+ ++++ IG
Sbjct: 23042 EEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGR 23101
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
P P V W + L Q+T E ++ S+LT+ + ++D G V + N G
Sbjct: 23102 PTPAVTWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAG 23154
Score = 45.6 bits (103), Expect = 0.002
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQK----SGLCEIHIKEAFP 1347
V GE + + + G P PKI+W NE +IE D + I++++ E+ I +A
Sbjct: 16337 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 16396
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
E G Y TASN+ G +++E Y+ PS ++D K
Sbjct: 16397 EDKGTYTVTASNRLGSVFRN--VHVEVYDR-PSPPRNLAVTDIK 16437
Score = 44.8 bits (101), Expect = 0.003
Identities = 50/215 (23%), Positives = 92/215 (42%), Gaps = 30/215 (13%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
AP+I + + + T +G + +G P P+ W + G ++ +S +D
Sbjct: 2077 APKIFERIQSQ-TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + +V +D+ I+ +A N G T++ A L V++ + +T +ELQ +
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA---------KQLITFTQELQDVV-- 2184
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
KE ++ + TFE + P ++ WYKD + +++ + +
Sbjct: 2185 -------AKE-------KDTMATFEC-ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVH 2229
Query: 1579 TCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+I T D E Y+C V D + T AKL V
Sbjct: 2230 FLSILTIDTSDAE-DYSCVLVEDENVKTT-AKLIV 2262
Score = 44.8 bits (101), Expect = 0.003
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G +R A G+P P +W G+E+ Y + E D+ +S+LT+ + DTGE
Sbjct: 18452 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV-ETDNFSSVLTIKNCLRRDTGEYQI 18510
Query: 1475 EAYNHLGVTATIAALSVESIVG 1496
N G L+V + G
Sbjct: 18511 TVSNAAGSKTVAVHLTVLDVPG 18532
Score = 44.8 bits (101), Expect = 0.003
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Query: 1405 ALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEV 1464
AL T V G+ +++ G P P V W + L Y IE D +S+LT+P+V
Sbjct: 28203 ALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS-SSLLTIPQV 28261
Query: 1465 YQDDTGEIVFEAYNHLG 1481
++DTG+ + N +G
Sbjct: 28262 TRNDTGKYILTIENGVG 28278
Score = 44.8 bits (101), Expect = 0.003
Identities = 22/75 (29%), Positives = 37/75 (49%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E + +A+ G P P + W+KD I I + T+ ++ AT+D G YT +A
Sbjct: 28901 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 28960
Query: 1598 VSDIGLAVTKAKLQV 1612
+ G A + K++V
Sbjct: 28961 KNASGSAKAEIKVKV 28975
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I+ +P +T GK +R+EA G P P +W + E++ S+ + + D +SIL
Sbjct: 19827 PKIL--MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKA-DSSSIL 19883
Query: 1460 TMPEVYQDDTGEIVFEAYNHLG 1481
+ +V + D+G A N G
Sbjct: 19884 IIKDVTRKDSGYYSLTAENSSG 19905
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+V G I++E +G PKP V W ++G ++L+ T+ E ++IL + E + D
Sbjct: 22001 LVIAKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSD 22059
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVG 1496
+G A N +G + + V I G
Sbjct: 22060 SGPYPLTARNIVGEVGDVITIQVHDIPG 22087
Score = 44.0 bits (99), Expect = 0.005
Identities = 18/57 (31%), Positives = 31/57 (54%)
Query: 1546 YSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ G P P + W KD K + +D R+ IEN ++ + TI + T++ G Y + +G
Sbjct: 28222 FKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 28278
Score = 43.2 bits (97), Expect = 0.009
Identities = 83/392 (21%), Positives = 161/392 (41%), Gaps = 32/392 (8%)
Query: 142 VIEEHVKVQEVVETKLWRKPKTISEKKDLLQV--STHEDTNILKVENLESVNVDTTSSKL 199
+I+ K +EV + RK + EK+ + + + H++ + +E+ E D +
Sbjct: 9954 IIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVF-IESFEEP-YDELEVEP 10011
Query: 200 ETKSWRKPRLEESLEEVGPTKGVNEPEVCH-WRKP--KTSEILK-----DKNEEEIRVQE 251
T+ + +P EE E+ K + EV W + + E + D+ EEE
Sbjct: 10012 YTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAY 10071
Query: 252 MKKQSTKAL-EVKDES-KQKIPWTQEAIKLRPT-KVEKSPIEKEKIEDVALKPVRKDSLM 308
+++ + EV +ES ++K+P K P KV K P+ EKIE + + + ++ +
Sbjct: 10072 QEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVI-EKIEKTSRR-MEEEKVQ 10129
Query: 309 DEKSSEISE--LQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEI 366
K E+S+ + + T +E + E ++ K+ ++SEE + +
Sbjct: 10130 VTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKM---VISEEKMFFASHTEEEVSV 10186
Query: 367 TQKEVALKTVRXXXXXXXXXXXXXSLKPVLTT-EKESKETEDRINTKDTRKPSIPWTQEA 425
T EV + V V EK + E + +P P E
Sbjct: 10187 TVPEVQKEIVTEEKIHVAVSKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEV 10246
Query: 426 IKLRPTKMEKTPI---EKE-----KFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKE 477
K +P EK P+ +KE K ++ KP ++ + + ++ A + + +++K
Sbjct: 10247 PK-KPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKR 10305
Query: 478 EHKPDKVSENNAPEERKWPTGKRQPKEETPQE 509
+K++ EE P PK++ P+E
Sbjct: 10306 VVTEEKITIVTQREESPPPAVPEIPKKKVPEE 10337
Score = 43.2 bits (97), Expect = 0.009
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTC---K 1596
V E Y G P P I W KD ++ E EN+ T +IK A K+ G YT
Sbjct: 28508 VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN 28567
Query: 1597 AVSDIGLAVT 1606
AV I + +T
Sbjct: 28568 AVCRIAVPIT 28577
Score = 42.7 bits (96), Expect = 0.012
Identities = 48/212 (22%), Positives = 80/212 (37%), Gaps = 27/212 (12%)
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
RI++ P +T T G LE G P+ +W + G EL +++ I ++ S L
Sbjct: 7573 RIIEK-PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVAS-LK 7630
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+P D G FE N +G + ++ V + P ++ ++++ A L A+
Sbjct: 7631 IPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV-----SDRIVPPSFIRKLKDVNAILGAS- 7684
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
V E SG+ + W++D I + + EN T
Sbjct: 7685 -------------------VVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 7725
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ G YTC A + G A L V
Sbjct: 7726 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 7757
Score = 42.7 bits (96), Expect = 0.012
Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Query: 1232 QPLKALNV-LEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLE 1289
+P+K L +EE + D V+ RA N G + S I E D D P +
Sbjct: 15264 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV--SEPSEISENVVAKDPDCKPTIDLETH 15321
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
+ V++GE++S+ P P + W + K ++ + +T+ + + ++
Sbjct: 15322 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS-AHLEVPKSVRAD 15380
Query: 1350 AGIYKCTASNQFGKCS 1365
AGIY T N+ G +
Sbjct: 15381 AGIYTITLENKLGSAT 15396
Score = 42.7 bits (96), Expect = 0.012
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 9/131 (6%)
Query: 1368 CILNIEAYEYVPSVSEEDVLSD-EKTSDV---EEFA-PRIVKALPTVVTTTEGKLIRLEA 1422
C+ N + YE+ E SD KT +V E+ P + L V+T G IRLEA
Sbjct: 19092 CVEN-QIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEA 19150
Query: 1423 KAIGIPKPQVRWL--RQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHL 1480
G P P+V W + T+L +S +I+ D +S ++ + + D G+ V A N
Sbjct: 19151 GVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD-SSKFSLTKAKRSDGGKYVVTATNTA 19209
Query: 1481 GVTATIAALSV 1491
G A ++V
Sbjct: 19210 GSFVAYATVNV 19220
Score = 42.7 bits (96), Expect = 0.012
Identities = 21/68 (30%), Positives = 30/68 (44%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P I W KD + ++ R +E T IK+ KD G YT A + G A
Sbjct: 25264 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATEN 25323
Query: 1608 AKLQVFQR 1615
+ V ++
Sbjct: 25324 LSVIVLEK 25331
Score = 42.7 bits (96), Expect = 0.012
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLV-LAP--LENTTVMDGERISLNCKILGRPWPK 1312
A N G++S S T + P+V P + + GE + + + GRP P+
Sbjct: 28857 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 28916
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ WF + IE ++ I+ G + +++A + G+Y A N G E + +
Sbjct: 28917 VTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 28975
Query: 1373 E 1373
+
Sbjct: 28976 Q 28976
Score = 42.3 bits (95), Expect = 0.016
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 8/116 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ TC A N AGS S V+E + P ++ V+ G ++ I G P
Sbjct: 7736 GIYTCVAANVAGSDECSAVLTVQEPPSFE-QTP------DSVEVLPGMSLTFTSVIRGTP 7788
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
K+ WF + + IS + + E+ + E P +G Y C +N G S
Sbjct: 7789 PFKVKWFKGSRELVPGESCNISLE-DFVTELELFEVQPLESGDYSCLVTNDAGSAS 7843
Score = 42.3 bits (95), Expect = 0.016
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV G + L+ + G+P P + W + L++ A I ++ Q++ LC + + + +G
Sbjct: 20233 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDSG 20291
Query: 1352 IYKCTASNQFGKCSTECILNI 1372
Y TA N G S L +
Sbjct: 20292 DYTITAENSSGSKSATIKLKV 20312
Score = 41.9 bits (94), Expect = 0.022
Identities = 32/145 (22%), Positives = 62/145 (42%), Gaps = 11/145 (7%)
Query: 1239 VLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQ---------TCIDGDAPLVLAPL 1288
VLE +++K G C+A N AGS +T ++++ +DG V P
Sbjct: 9329 VLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP- 9387
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
++ V++ + K+ G P P + W + QK ++ I++
Sbjct: 9388 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKT 9447
Query: 1349 MAGIYKCTASNQFGKCSTECILNIE 1373
+G+Y+C A N+ G+ + L ++
Sbjct: 9448 DSGLYRCVAFNEHGEIESNVNLQVD 9472
Score = 41.9 bits (94), Expect = 0.022
Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++E G PKP + W + G L Q+T + + D T+ L++ E ++DD G+
Sbjct: 24171 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT-LSIKETHKDDGGQYGI 24229
Query: 1475 EAYNHLG-VTATIAALSVE 1492
N +G TA+I ++++
Sbjct: 24230 TVANVVGQKTASIEIVTLD 24248
Score = 41.9 bits (94), Expect = 0.022
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + P ++ GE + + ++GRP P I W + + ++ + + + +H
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LH 25297
Query: 1342 IKEAFPEMAGIYKCTASNQFG 1362
IKE + G Y TA+N G
Sbjct: 25298 IKEGNKDDFGKYTVTATNSAG 25318
Score = 41.5 bits (93), Expect = 0.029
Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 1/107 (0%)
Query: 1509 MEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER 1568
MEE A L + V++ P V E T E +G P + WYKD K++ + ++
Sbjct: 6618 MEENMATLMVLEPA-VIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQK 6676
Query: 1569 FIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
++ I + GTYT + +++G + A + V R
Sbjct: 6677 HKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDR 6723
Score = 41.5 bits (93), Expect = 0.029
Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 15/170 (8%)
Query: 1236 ALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT-VM 1294
AL + E ++D G C A N G S S T + AP V + +
Sbjct: 7347 ALLTINEASAEDS-GDYICEAHNGVGDASCS--------TALTVKAPPVFTQKPSPVGAL 7397
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C+I G P ++ W + K + ++ I+ K +HI G Y
Sbjct: 7398 KGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLHILNLEASDVGEYH 7456
Query: 1355 CTASNQFGKCSTECILNI-EAYEYVPSVSEEDVL---SDEKTSDVEEFAP 1400
C A+N+ G + C + E +V +S+ L + E + VE F P
Sbjct: 7457 CKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQP 7506
Score = 41.5 bits (93), Expect = 0.029
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
V+ G+++++ A G P P + W + G E+ + +I D+ T +LT+ + + D
Sbjct: 26725 VIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT-LLTVKDCIRRD 26783
Query: 1469 TGEIVFEAYNHLGVTATIA 1487
TG+ V N G T ++A
Sbjct: 26784 TGQYVLTLKNVAG-TRSVA 26801
Score = 41.1 bits (92), Expect = 0.038
Identities = 40/173 (23%), Positives = 75/173 (43%), Gaps = 11/173 (6%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSS--IVEEQTCIDGDAPLVLAPL 1288
I +K L + N+++ A N AG + S IV+EQT + L L +
Sbjct: 21941 ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP---ELDLRGI 21997
Query: 1289 ENTTVMD--GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
V+ G+ I + +LGRP P + W +++++ + + + ++I E
Sbjct: 21998 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECV 22056
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+G Y TA N G+ ++ I+ ++ +P + DE +SD F+
Sbjct: 22057 RSDSGPYPLTARNIVGEVGD--VITIQVHD-IPGPPTGPIKFDEVSSDFVTFS 22106
Score = 41.1 bits (92), Expect = 0.038
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGT 1592
VH E EA G P P+++W KD K + T R I++ +TT +K + G
Sbjct: 25646 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 25705
Query: 1593 YTCKAVSDIG 1602
Y K +S++G
Sbjct: 25706 YILK-LSNVG 25714
Score = 41.1 bits (92), Expect = 0.038
Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 6/119 (5%)
Query: 1379 PSVSEEDVLS-DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
PS S +++ DE + EF P L G+ +R++A G P P+V W +
Sbjct: 28867 PSQSSGIIMTRDENVPPIVEFGPEYFDGL----IIKSGESLRIKALVQGRPVPRVTWFKD 28922
Query: 1438 GTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
G E+ + +I ++ TS L + + +D G EA N G + V+ G
Sbjct: 28923 GVEIEKRMNMEITDVLGSTS-LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 28980
Score = 40.7 bits (91), Expect = 0.050
Identities = 56/260 (21%), Positives = 98/260 (37%), Gaps = 35/260 (13%)
Query: 1234 LKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
+ +L +L ++ + G T + +N G S + V ++ P L+NT
Sbjct: 6685 ISSLRIL--SVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAV----PPSFTRRLKNTGG 6738
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
+ G L CK+ G + WFH + K++ A+ T +C + + G
Sbjct: 6739 VLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF--SDNVCTLQLNSLDSSDMGN 6796
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G +L ++ E S V+E P ++ LP
Sbjct: 6797 YTCVAANVAGSDECRAVLTVQ----------------EPPSFVKE--PEPLEVLP----- 6833
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
GK + + G P +V W R EL++ I +D + L + + +GE
Sbjct: 6834 --GKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELELFNIDISQSGEY 6890
Query: 1473 VFEAYNHLGVTATIAALSVE 1492
N+ G + L V+
Sbjct: 6891 TCVVSNNAGQASCTTRLFVK 6910
Score = 40.3 bits (90), Expect = 0.066
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR--TDERFI----IENKENRTTCTIKKAT 1586
+V E V A +G P P+I W K+ VI TD I + E +T +I KA
Sbjct: 16336 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 16395
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
++ +GTYT A + +G ++V+ R
Sbjct: 16396 REDKGTYTVTASNRLGSVFRNVHVEVYDR 16424
Score = 39.9 bits (89), Expect = 0.087
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T G I L A G P+P++ W + L Q IE + S +T+ + + DT
Sbjct: 14627 LTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK-KSTVTIVDSKRSDT 14685
Query: 1470 GEIVFEAYNHLGVTATIAALSV 1491
G + EA N G + ++V
Sbjct: 14686 GTYIIEAVNVCGRATAVVEVNV 14707
Score = 39.9 bits (89), Expect = 0.087
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G+ RLEA G P P + WLR E+ +S +I+ D ++L + + + D
Sbjct: 24562 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN-TDFKALLIVKDAIRIDG 24620
Query: 1470 GEIVFEAYNHLG 1481
G+ + A N G
Sbjct: 24621 GQYILRASNVAG 24632
Score = 39.5 bits (88), Expect = 0.12
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRI--VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
++S SD T E PRI A+ +++T G + L+A G P P V W +
Sbjct: 20200 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 20259
Query: 1438 GTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
GT LL+ E + L + V + D+G+ A N G + L V
Sbjct: 20260 GT-LLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 20312
Score = 39.5 bits (88), Expect = 0.12
Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
T + G P P +LW K + +RT R ++ ++RT+ TI+ A ++ G YT
Sbjct: 27132 TMTVPFRGRPVPNVLWSKPDTDLRT--RAYVDTTDSRTSLTIENANRNDSGKYT 27183
Score = 39.1 bits (87), Expect = 0.15
Identities = 22/99 (22%), Positives = 44/99 (44%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
+AL + + T +E + V + + T + +SG W+KD + + ++ I
Sbjct: 5497 SALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISV 5556
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + I K G YT + +D+G + KA++ V
Sbjct: 5557 TDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINV 5595
Score = 39.1 bits (87), Expect = 0.15
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 1513 QAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE 1572
+A L + P F ++ E++ V + S P + W+KD K I+ + +I+
Sbjct: 12935 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIK 12993
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ +KKA K G YTC D G T KL + R
Sbjct: 12994 ADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 13032
Score = 39.1 bits (87), Expect = 0.15
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 1544 AIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGL 1603
A+ +G P P +W K+ + D R +I+N ++ IK A + G Y A + G
Sbjct: 16053 AVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGS 16111
Query: 1604 AVTKAKLQVF 1613
A+++VF
Sbjct: 16112 KFAAARVEVF 16121
Score = 39.1 bits (87), Expect = 0.15
Identities = 22/73 (30%), Positives = 28/73 (38%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V F AI G P P W D I+TDE + +E + TIK + G Y +
Sbjct: 18455 VRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSN 18514
Query: 1600 DIGLAVTKAKLQV 1612
G L V
Sbjct: 18515 AAGSKTVAVHLTV 18527
Score = 39.1 bits (87), Expect = 0.15
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTMPEVYQD 1467
V+T G+ IR+ A+ G P+P + W ++G L++ E +++ + D + L + E +
Sbjct: 18844 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR--EKRVDLIQDLPRVELQIKEAVRA 18901
Query: 1468 DTGEIVFEAYNHLGVTATIAALSV 1491
D G+ + A N G A ++V
Sbjct: 18902 DHGKYIISAKNSSGHAQGSAIVNV 18925
Score = 39.1 bits (87), Expect = 0.15
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV G+ I + ++ GRP P I W K++ + + + Q E+ IKEA G
Sbjct: 18846 TVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI-QDLPRVELQIKEAVRADHG 18904
Query: 1352 IYKCTASNQFGKCSTECILNI 1372
Y +A N G I+N+
Sbjct: 18905 KYIISAKNSSGHAQGSAIVNV 18925
Score = 39.1 bits (87), Expect = 0.15
Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRI---VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLR 1436
++S SD T + AP+I VK TV+ G+ RLEA G P P + W +
Sbjct: 22366 AISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKA-GEAFRLEADVSGRPPPTMEWSK 22424
Query: 1437 QGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
G EL + + +I+ D T+++ + D+G A N G I + V G
Sbjct: 22425 DGKELEGTAKLEIKIADFSTNLVNKDST-RRDSGAYTLTATNPGGFAKHIFNVKVLDRPG 22483
Query: 1497 TQE 1499
E
Sbjct: 22484 PPE 22486
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P V P V E++ ++ GRP ++W + + ++ + +S K+ + +
Sbjct: 26322 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKT-VTSLS 26380
Query: 1342 IKEAFPEMAGIYKCTASNQFG 1362
IKEA E G Y+ SN G
Sbjct: 26381 IKEASKEDVGTYELCVSNSAG 26401
Score = 38.3 bits (85), Expect = 0.27
Identities = 21/90 (23%), Positives = 38/90 (42%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT E V E E ++ + P P + W+KD K ++ +R ++N +
Sbjct: 15314 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 15373
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K+ + G YT + +G A ++V
Sbjct: 15374 PKSVRADAGIYTITLENKLGSATASINVKV 15403
Score = 37.9 bits (84), Expect = 0.35
Identities = 22/90 (24%), Positives = 38/90 (42%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F+K+I F+A G+ + W KD+ I D+ + + N + +
Sbjct: 5413 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 5472
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+G Y C+A +D G+ A L V
Sbjct: 5473 SGIEVKHDGKYVCQAKNDAGIQRCSALLSV 5502
Score = 37.9 bits (84), Expect = 0.35
Identities = 22/82 (26%), Positives = 36/82 (43%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
VH E +A G P P I W K ++ + R I++ + T+ ++K A + G Y
Sbjct: 23482 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNY 23541
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
KA + G ++V R
Sbjct: 23542 ILKAKNVAGERSVTVNVKVLDR 23563
Score = 37.9 bits (84), Expect = 0.35
Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++A G P P ++W++ EL + +I+ D TS L++ + + D+G +
Sbjct: 23485 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS-LSVKDAVRVDSGNYIL 23543
Query: 1475 EAYNHLGVTATIAALSVESIVGTQE 1499
+A N G + + V G E
Sbjct: 23544 KAKNVAGERSVTVNVKVLDRPGPPE 23568
Score = 37.5 bits (83), Expect = 0.47
Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 10/146 (6%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKID 1314
+A N AG + S+ V C D P + E V +G +++ KI G P+P +
Sbjct: 17019 KAVNAAGV--SKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLT 17076
Query: 1315 WFH-NEKLIETARDITISRQKSGL-----CEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
WF K + + + L C + I ++ G+Y TA N G S E
Sbjct: 17077 WFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEM 17136
Query: 1369 ILNIEAYEYVP--SVSEEDVLSDEKT 1392
LN+ P + E V +D+ T
Sbjct: 17137 RLNVLGRPGPPVGPIKFESVSADQMT 17162
Score = 37.5 bits (83), Expect = 0.47
Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+++I RV + + A G P P+I W K+ KV+ ++R + R IK+A
Sbjct: 18842 RDVITVRVGQT--IRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAV 18899
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ G Y A + G A A + V R
Sbjct: 18900 RADHGKYIISAKNSSGHAQGSAIVNVLDR 18928
Score = 37.5 bits (83), Expect = 0.47
Identities = 22/65 (33%), Positives = 29/65 (44%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+ W K K IR + I + + TIK AT+ G YT A + G V
Sbjct: 21332 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 21391
Query: 1608 AKLQV 1612
K+ V
Sbjct: 21392 VKVTV 21396
Score = 37.1 bits (82), Expect = 0.61
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLE--NTTVMD-GERISLNCKILGRPWP 1311
A+N AG++S S + TC D +AP + ++ +T ++ GE L + GRP P
Sbjct: 22360 AKNAAGAISPP-SEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPP 22418
Query: 1312 KIDWFHNEKLIE-TAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
++W + K +E TA+ +I I+ + L K++ +G Y TA+N G + I
Sbjct: 22419 TMEWSKDGKELEGTAKLEIKIADFSTNLVN---KDSTRRDSGAYTLTATNPGG--FAKHI 22473
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSD 1394
N++ + P E + E TS+
Sbjct: 22474 FNVKVLDR-PGPPEGPLAVTEVTSE 22497
Score = 37.1 bits (82), Expect = 0.61
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 7/109 (6%)
Query: 1288 LENT-TVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDITISRQKSGLCEIHIKEA 1345
L NT TV+ GE + ++ +GRP P + W N L +T R S + + L + IK+A
Sbjct: 23080 LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSL--LTIKDA 23137
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
E G Y +N G+ LN+ + P V DE T+D
Sbjct: 23138 CREDVGHYVVKLTNSAGEAIE--TLNVIVLD-KPGPPTGPVKMDEVTAD 23183
Score = 37.1 bits (82), Expect = 0.61
Identities = 19/60 (31%), Positives = 28/60 (46%)
Query: 1543 EAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E SG P P I W KD ++ R + + + TT +IK+ KD G Y + +G
Sbjct: 24177 EVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG 24236
Score = 37.1 bits (82), Expect = 0.61
Identities = 19/82 (23%), Positives = 36/82 (43%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E + + + G P + W KD + ++ R + + + T+ +IK+A+K+ GTY
Sbjct: 26333 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 26392
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
+ G + V R
Sbjct: 26393 ELCVSNSAGSITVPITIIVLDR 26414
Score = 36.7 bits (81), Expect = 0.81
Identities = 57/255 (22%), Positives = 104/255 (40%), Gaps = 21/255 (8%)
Query: 261 EVKDESKQKIPWTQEAIKLRPTKVEKSPI----EKEKIEDVALKPVRKDSLMDEKSSEIS 316
EV E K +P ++ ++ PTKV + P EK+ E + KP + E+ E++
Sbjct: 11542 EVVPEKKVPVPPPKKP-EVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVA 11600
Query: 317 ELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTV 376
+ ++ E+ E Q+ K + E +++ K+ + + EV + V
Sbjct: 11601 LEEPPAEVVEEPEPAAPPQVTVPPKKPVPE----KKAPAVVAKKPELPPVKVPEVPKEVV 11656
Query: 377 RXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKT 436
KP K + ++ + K K ++P E + ++ K
Sbjct: 11657 PEKKVPLVVPK-----KPEAPPAKVPEVPKEVVPEK---KVAVPKKPEVPPAKVPEVPKK 11708
Query: 437 PIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKWP 496
P+ +EK P R +S E+ EE + ++I EE KP V+E PE P
Sbjct: 11709 PVLEEK--PAVPVPERAESPPPEVYEEPEEIAPE-EEIAPEEEKPVPVAEEEEPEVPP-P 11764
Query: 497 TGKRQPKEETPQEEV 511
+PK+ P+++V
Sbjct: 11765 AVPEEPKKIIPEKKV 11779
Score = 36.7 bits (81), Expect = 0.81
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ----KSGLCEI 1340
++PLE+ TV +GE + C+ L + WF N+ + T+R + IS + K + E+
Sbjct: 12504 MSPLEDQTVKEGETATFVCE-LSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEV 12562
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
+ + A + + +++ Q + ++ ++ +E L E + DV
Sbjct: 12563 TLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDV 12617
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/78 (29%), Positives = 33/78 (42%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E EA SG P P + W KD K + + I+ + T K +T+ G YT A
Sbjct: 22404 EAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 22463
Query: 1598 VSDIGLAVTKAKLQVFQR 1615
+ G A ++V R
Sbjct: 22464 TNPGGFAKHIFNVKVLDR 22481
Score = 36.7 bits (81), Expect = 0.81
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
T + SG P P++ W + ++ +R I ++RTT T+K + + G Y +
Sbjct: 29593 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 29652
Query: 1601 IGLAVTKAKLQVFQR 1615
G+ + V R
Sbjct: 29653 AGVKTFSVTVVVIGR 29667
Score = 36.3 bits (80), Expect = 1.1
Identities = 40/205 (19%), Positives = 80/205 (39%), Gaps = 9/205 (4%)
Query: 1525 FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKK 1584
F++ + +V E+E+ FE S ++ W+KD I+ +++ I +K I K
Sbjct: 13303 FLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 13361
Query: 1585 ATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXXXXXXXXXXXXXXXXXXXXEEESVGV 1644
D E Y+C ++ A T L V + E S
Sbjct: 13362 CLLDDEAEYSC----EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPG 13417
Query: 1645 EDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSESEHIETEDIALQKKVDEKTKG-IPV 1703
+ + + E+ + + +KR I+V ++ H+E + +T G + V
Sbjct: 13418 AEVIWYKGDEEIIETGRYEILTEGRKR---ILVIQNAHLEDAGNYNCRLPSSRTDGKVKV 13474
Query: 1704 EEKAKPILTTHEHVVLSEQQEGESV 1728
E A ++ +++ + E ++ E V
Sbjct: 13475 HELAAEFISKPQNLEILEGEKAEFV 13499
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A L +V FVKE+ V E E I S E WY ++ ++++ ++ I +
Sbjct: 2258 AKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKYTITS 2316
Query: 1574 KENRTTCTIKKATKDLEGTYT 1594
+ R T+K TK+ +G Y+
Sbjct: 2317 RRGRQNLTVKDVTKEDQGEYS 2337
Score = 35.9 bits (79), Expect = 1.4
Identities = 82/377 (21%), Positives = 146/377 (38%), Gaps = 42/377 (11%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKP 207
K +E K+ PK + EK+ +L ++ +L VE E + S E P
Sbjct: 11130 KKEEAPPAKVPEVPKKVEEKRIILP----KEEEVLPVEVTEEPEEEPISE--EEIPEEPP 11183
Query: 208 RLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESK 267
+EE +EEV P P+ E++K E K ++ A K +
Sbjct: 11184 SIEE-VEEVAP--------------PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 11228
Query: 268 QKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNERQITEK 327
+K+P + + P KV + P K+ E L P +K+++ K + L+ + + +
Sbjct: 11229 EKVPVPVQKKEAPPAKVPEVP--KKVPEKKVLVP-KKEAVPPAKGRTV--LEEKVSVAFR 11283
Query: 328 KESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXX 387
+E + + +L+ +E I EE + + E + E +K +
Sbjct: 11284 QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVE 11343
Query: 388 XXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDIT 447
+ V E++E E + K P P E K+ P K T + K
Sbjct: 11344 KVHRVIEVF----EAEEVE--VFEKPKAPPKGPEISE--KIIPPKKPPTKVVPRKEPPAK 11395
Query: 448 LKPTRKQSLVDE---ITEEVCALKSALDDI-EKEEHKPDK---VSENNAPEERKWPTGKR 500
+ K+ +V+E + EE + + D+ +E P+K V PE P
Sbjct: 11396 VPEVPKKIVVEEKVRVPEEPRVPPTKVPDVLPPKEVVPEKKVPVPPAKKPEAPP-PKVPE 11454
Query: 501 QPKEETPQEEVVLKPTR 517
PKE P+++V + P +
Sbjct: 11455 APKEVVPEKKVPVPPPK 11471
Score = 35.9 bits (79), Expect = 1.4
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A LK ++ P F ++ + E++ +T + S + P + W+KD + I ++ I+
Sbjct: 12581 AQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VP-VKWFKDGEEIVPSPKYSIKA 12638
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
R IKKA +G Y C D G TKA + V R
Sbjct: 12639 DGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEAR 12676
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKID 1314
RAEN AG +S + + DAP V+ + V G+ I+L+ I G P+P I
Sbjct: 15582 RAENAAG-ISEPSRATPPTKAVDPIDAPKVILRT-SLEVKRGDEIALDASISGSPYPTIT 15639
Query: 1315 WFHNEKLI 1322
W +E +I
Sbjct: 15640 WIKDENVI 15647
Score = 35.9 bits (79), Expect = 1.4
Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
Query: 1415 GKLIRLEAKAIGIPKPQVRW------LRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
G+ + + A G+P P++ W + + T+ LQ T+ ++ + T L++P+ ++D
Sbjct: 16340 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-LSIPKAVRED 16398
Query: 1469 TGEIVFEAYNHLG 1481
G A N LG
Sbjct: 16399 KGTYTVTASNRLG 16411
Score = 35.5 bits (78), Expect = 1.9
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
L +E I ++ K E+ + +Q L T+ V T +K+I + V ++ FE
Sbjct: 9551 LEIEEIERSERDEK-EFEELVSFIQQRLSQTEPV-TLIKDIENQTVLKDNDAVFEIDIKI 9608
Query: 1549 N-PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
N P ++ WYK + + ++F I +R T +K +G Y G +
Sbjct: 9609 NYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIAS 9664
Query: 1608 AKLQVFQ 1614
AKL V +
Sbjct: 9665 AKLTVIE 9671
Score = 35.5 bits (78), Expect = 1.9
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 10/120 (8%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
++ PL++T V + + + NC++ K WF NE+ I + I QK + + I+
Sbjct: 13569 IVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIR 13626
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
+A + Y + +N G+ + + N+ V EED+ E D+E + V
Sbjct: 13627 DAHLDDQANYNVSLTNHRGE-NVKSAANL-------IVEEEDLRIVEPLKDIETMEKKSV 13678
Score = 35.1 bits (77), Expect = 2.5
Identities = 19/76 (25%), Positives = 31/76 (40%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V +A G P P + W KD +++ E + + N T + + G YT A +
Sbjct: 20240 VCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 20299
Query: 1600 DIGLAVTKAKLQVFQR 1615
G KL+V +
Sbjct: 20300 SSGSKSATIKLKVLDK 20315
Score = 35.1 bits (77), Expect = 2.5
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 4/113 (3%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLV-LAP-LENTTVMD-GERISLNCKILGRPWPK 1312
A+N AG++S S + + P + + P +T V++ GE L + G+P P
Sbjct: 24524 AKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPT 24583
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
I+W +K IE + I I +K+A G Y ASN G S
Sbjct: 24584 IEWLRGDKEIEESARCEIKNTDFKALLI-VKDAIRIDGGQYILRASNVAGSKS 24635
Score = 34.7 bits (76), Expect = 3.3
Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Query: 1255 RAENFAG--SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
+A+N AG + SS++ ++ I+ A L + T G +++ I GRP PK
Sbjct: 29546 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 29605
Query: 1313 IDWFHNE-KLIETAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
+ W E +L ET R IT ++ ++ L +K++ +G Y T N G
Sbjct: 29606 VTWKLEEMRLKETDRVSITTTKDRTTLT---VKDSMRGDSGRYFLTLENTAG 29654
Score = 34.3 bits (75), Expect = 4.3
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L TV G +I L + G+P PKI W + +++ + ITI + I ++
Sbjct: 14624 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK-KSTVTIVDSKR 14682
Query: 1348 EMAGIYKCTASNQFGKCSTECILNI 1372
G Y A N G+ + +N+
Sbjct: 14683 SDTGTYIIEAVNVCGRATAVVEVNV 14707
Score = 34.3 bits (75), Expect = 4.3
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKV--IRTDERFIIENKENRTTCTIKKATKDLEGTYTC 1595
+ + EA G P PE+ W KD + R I+ + + + ++ KA + G Y
Sbjct: 19144 DTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVV 19203
Query: 1596 KAVSDIGLAVTKAKLQVFQR 1615
A + G V A + V +
Sbjct: 19204 TATNTAGSFVAYATVNVLDK 19223
Score = 34.3 bits (75), Expect = 4.3
Identities = 22/82 (26%), Positives = 34/82 (41%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V+ E EA G P P I W + +K I R I+N + + +K A + G Y
Sbjct: 24564 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 24623
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
+A + G ++V R
Sbjct: 24624 ILRASNVAGSKSFPVNVKVLDR 24645
Score = 33.9 bits (74), Expect = 5.7
Identities = 83/383 (21%), Positives = 144/383 (37%), Gaps = 23/383 (6%)
Query: 139 ERGVIEEHVKVQEVVETKLWR-KPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSS 197
E V++ K +E K+ + + + E+K ++ E I +V +E T
Sbjct: 10601 EEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLE 10660
Query: 198 KLETKSWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQST 257
+ R+ EE E EP + + + E ++ EE +E +
Sbjct: 10661 EEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEH---EEYITEPE 10717
Query: 258 KALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDS-LMDEKSSEIS 316
K + VK ++ +P +A P KV K + +EK+ K ++ + E+ ++
Sbjct: 10718 KPIPVKPVPEEPVPTKPKA---PPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVF 10774
Query: 317 ELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTV 376
E + IT K+E Q T+ P K + V E K ++ + EV K +
Sbjct: 10775 EEKIRISIT-KREKEQVTE--PAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVP-KEL 10830
Query: 377 RXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKT 436
+ ++ E+E E+ T++ P IP + +P EK
Sbjct: 10831 EPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK 10890
Query: 437 PIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSE---NNAPEER 493
P+ K ++ P K V + EE K + +KE+ P KV E PEE+
Sbjct: 10891 PVPVPKKKE---APPAKVPEVPKKPEE----KVPVLIPKKEKPPPAKVPEVPKKPVPEEK 10943
Query: 494 -KWPTGKRQPKEETPQEEVVLKP 515
P K+ EV KP
Sbjct: 10944 VPVPVPKKVEAPPAKVPEVPKKP 10966
Score = 33.9 bits (74), Expect = 5.7
Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E +L + A + VSE +S+ + + P I ++ EG+ + +
Sbjct: 15282 EYVLRVRAVNAI-GVSEPSEISENVVAKDPDCKPTIDLETHDIIVI-EGEKLSIPVPFRA 15339
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG-VTAT 1485
+P P V W + G E+ S ++ D ++ L +P+ + D G N LG TA+
Sbjct: 15340 VPVPTVSWHKDGKEVKASDRLTMKN-DHISAHLEVPKSVRADAGIYTITLENKLGSATAS 15398
Query: 1486 I 1486
I
Sbjct: 15399 I 15399
Score = 33.9 bits (74), Expect = 5.7
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G+ + L+ I G P+PK+ W ++ T I ++ S ++ I+ A E GIY
Sbjct: 18160 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS---KLEIRNAAHEDGGIYSL 18216
Query: 1356 TASNQFG 1362
T N G
Sbjct: 18217 TVENPAG 18223
Score = 33.9 bits (74), Expect = 5.7
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 6/111 (5%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM---DGERISLNCKILGRPWPK 1312
A N A SVS S D + P V+ ++ V+ GE + +N I GRP P
Sbjct: 26688 ARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV 26747
Query: 1313 IDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
I W + ++ E AR IS L + +K+ G Y T N G
Sbjct: 26748 ISWAKDGIEIEERARTEIISTDNHTL--LTVKDCIRRDTGQYVLTLKNVAG 26796
Score = 33.5 bits (73), Expect = 7.6
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD------DGTSILTMPEVYQD 1467
EG + + AK G+P P + W + + + E + + D T L +P+ +
Sbjct: 17057 EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 17116
Query: 1468 DTGEIVFEAYNHLGVTATIAALSV 1491
DTG A N+LG + L+V
Sbjct: 17117 DTGLYTITAVNNLGTASKEMRLNV 17140
Score = 33.5 bits (73), Expect = 7.6
Identities = 15/47 (31%), Positives = 20/47 (42%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
G P P + W K + TD R +E+ TT + K G YT
Sbjct: 20935 GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYT 20981
Score = 33.5 bits (73), Expect = 7.6
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
E++ A +G P P I W KD I R I + +N T T+K + G Y
Sbjct: 26732 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQY 26787
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 97.9 bits (233), Expect = 3e-19
Identities = 69/235 (29%), Positives = 108/235 (45%), Gaps = 25/235 (10%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P +++ L+N TV++GE ++L C I G P P + W+ + IE++ D I+ Q SG+ +
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-SGIARLM 955
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE-------------------YVPS-- 1380
I+EAF E +G + C+A N+ G ST C L ++ E +V S
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1015
Query: 1381 -VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
V + L++E+ E AP + P V EG + + G PKP V W + G
Sbjct: 1016 VVMTDTSLTEEQAGPGEPAAPYFI-TKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 1440 ELLQSTEYQIE-ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L Y++ G L + + DD GE N G T+ A+L E+
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1129
Score = 92.3 bits (219), Expect = 2e-17
Identities = 73/270 (27%), Positives = 123/270 (45%), Gaps = 17/270 (6%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P VL L+ TV G+ I GRP PKI W+ E+L+ T
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I EAFPE A +Y C A N +G +T L++E VP V D ++ +
Sbjct: 3251 LLI-EAFPEDAAVYTCEAKNDYGVATTSASLSVE----VPEVVSPD-------QEMPVYP 3298
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P I+ L V T+EG+ R + + G +V W + ++ S +++ + +D T L
Sbjct: 3299 PAIITPLQDTV-TSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQL 3355
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYR-KPEWVTHMEELQAALKA 1518
+ E Y +D G F A N +G ++ A LS+E+ R + E M+E ++ +
Sbjct: 3356 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLS 3415
Query: 1519 TQSVPTFVKEIIPERVHEE-EIVTFEAIYS 1547
+ E+ +++E E+++ +YS
Sbjct: 3416 AEEEGLHSAELQLSKINETLELLSESPVYS 3445
Score = 85.0 bits (201), Expect = 2e-15
Identities = 69/244 (28%), Positives = 108/244 (44%), Gaps = 18/244 (7%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E + +SE V S + S+ E P +K + + G + L IGIPKP+++W
Sbjct: 3433 ETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNA-DISMGDVATLSVTVIGIPKPKIQWF 3491
Query: 1436 RQGTELLQSTEYQ-IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
G L S +Y+ + + DD + I+ ++ +D GE A N G T A L + S
Sbjct: 3492 FNGVLLTPSADYKFVFDGDDHSLIILFTKL--EDEGEYTCMASNDYGKTICSAYLKINS- 3548
Query: 1495 VGTQEYRKPEWVTHMEELQAALKATQSV-----PTFVKEIIPERVHEEEIVTFEAIYSGN 1549
K E E A K+ + + P F+KE+ P R + FE G
Sbjct: 3549 -------KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 3601
Query: 1550 PTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P P + W+K+NK + T + II N T + ++ G Y CKA + +G + A
Sbjct: 3602 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 3661
Query: 1609 KLQV 1612
+L V
Sbjct: 3662 ELLV 3665
Score = 74.9 bits (176), Expect = 3e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 72.9 bits (171), Expect = 1e-11
Identities = 56/217 (25%), Positives = 92/217 (42%), Gaps = 7/217 (3%)
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+G P+ + + N + G+ +L+ ++G P PKI WF N L+ + D
Sbjct: 3453 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3512
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGK--CSTECILNIEAYEYVPSVSEEDVLSD-EKTSD 1394
I + E G Y C ASN +GK CS +N + + + +E V EK
Sbjct: 3513 SLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3571
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
P +K L + +G E +G P P V W ++ +L S Y I +
Sbjct: 3572 --PCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 3628
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
G+ + + ++D+G + +A N LG + A L V
Sbjct: 3629 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 69.3 bits (162), Expect = 1e-10
Identities = 47/161 (29%), Positives = 79/161 (49%), Gaps = 12/161 (7%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGD------APLVLAPLENTTVMDGERISLNCK 1304
V TC A+N G +TS S VE + D P ++ PL++T +G+ C+
Sbjct: 3262 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR 3321
Query: 1305 ILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
+ G K+ W+ +K I+ +R ++ Q ++ I EA+PE G Y ASN G+
Sbjct: 3322 VSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 3379
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
S+ L++EA E S+ E + E +++EF+ + A
Sbjct: 3380 SSTANLSLEAPE---SILHERI-EQEIEMEMKEFSSSFLSA 3416
Score = 67.3 bits (157), Expect = 5e-10
Identities = 78/361 (21%), Positives = 139/361 (38%), Gaps = 31/361 (8%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +V L V T EG+ + LE G P P V W R+ ++ S ++QI G + L
Sbjct: 897 PTLVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQIT-FQSGIARL 954
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSV--------ESIVGTQEYRKPE--WVTHM 1509
+ E + +D+G A N G +T L+V E+ T+++ E +V
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1510 EELQAALKATQ--------SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNK 1561
+ + T+ + P F+ + + +++ E V F GNP P + W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 1562 VIRTDERFIIENKENRTTC--TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXX 1619
+ T R+ + + C I D G YT + G A L + +
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADYEL 1133
Query: 1620 XXXXXXXXXXXXXXXXXXEEESVGVEDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSE 1679
+E VG E F + +K+ + ++K+ AK V
Sbjct: 1134 LMKSQQEMLYQTQVTAFVQEPKVG-ETAPGFVYSEYEKEYEKEQAL--IRKKMAKDTVVV 1190
Query: 1680 SEHIETEDIALQKKVDEKTKGIPVEEKAKPILTTHEHVVLSEQQEGESVEPFDESYQTQK 1739
++E ++ + + K E + + I TT E ++ + +E +V+ ES +
Sbjct: 1191 RTYVEDQEFHISSFEERLIK----EIEYRIIKTTLEELLEEDGEEKMAVD-ISESEAVES 1245
Query: 1740 G 1740
G
Sbjct: 1246 G 1246
Score = 67.3 bits (157), Expect = 5e-10
Identities = 110/486 (22%), Positives = 181/486 (37%), Gaps = 67/486 (13%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA--RDITISRQKSGLC 1338
A +L + TV +GE +C G P P + W +++ T+ +T ++ KS
Sbjct: 26063 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF- 26121
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE-------AYEYVPSV--------SE 1383
EI +A E G Y N GK E L I+ A P V S
Sbjct: 26122 EISSVQASDE--GNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSP 26179
Query: 1384 EDVLSDEKTSDVEEFAPRIVKALPTVVTTTE-------------GKLIRLEA-KAIG--- 1426
E V S ++ E P+ V T T TE + ++ EA K I
Sbjct: 26180 EAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLT 26239
Query: 1427 -------IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
+ +V W + G +L ++ +Q DGT L + + + D GE V E
Sbjct: 26240 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGE 26299
Query: 1480 LGVTAT------IAALSV-ESIVGTQEYRKPE------WVTHMEELQAALKATQSVPTFV 1526
G + T A S+ E + E +K + VT E +A + S P V
Sbjct: 26300 GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAP-EPISSKPVIV 26358
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+ V + + F +G P P +W KD K I ++ + + I K
Sbjct: 26359 TGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTD 26418
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXXXXXXXXXXXXXXXXXXXXEEESVGVED 1646
G YTC + G + KL + ++++V E+
Sbjct: 26419 TSDSGLYTCTVKNSAGSVSSSCKLTI----KAIKDTEAQKVSTQKTSEITPQKKAVVQEE 26474
Query: 1647 TLDFATVSEVQALDKQHSTDK--VKKRKAKIVVSESEHIETEDIALQKKV--DEKTKGIP 1702
A SE + + S +K +K+ +K+++SE E ++ +L+K + +E TK
Sbjct: 26475 ISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKKSAATSLEKSIVHEEITKTSQ 26533
Query: 1703 VEEKAK 1708
E+ +
Sbjct: 26534 ASEEVR 26539
Score = 66.9 bits (156), Expect = 7e-10
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G PTP + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 64.5 bits (150), Expect = 4e-09
Identities = 76/359 (21%), Positives = 131/359 (36%), Gaps = 42/359 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
++N +++G ++ +CK+ G P PKI W+ + K I+ + + G + I P
Sbjct: 1251 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1310
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
E GIY ASN G L +E P + + + E S + +PR V P
Sbjct: 1311 EDEGIYTAFASNIKGNAICSGKLYVE--PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSP 1368
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL-------- 1459
++ R+ + + + G L ++ E Q+E L +L
Sbjct: 1369 IRMSPARMSPARMSPARMSPAR-----MSPGRRLEETDESQLERLYKPVFVLKPVSFKCL 1423
Query: 1460 --------------TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
MPE + G+ + Y H V S+ IV EW
Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL-IIVPATPSDSGEW 1482
Query: 1506 VTHMEE----------LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEIL 1555
+ L Q P FV+++ + E + + +GNP P+I+
Sbjct: 1483 TVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIV 1542
Query: 1556 WYKDNKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
W K++ +I + + IE + I YT A++ G T+ K+ V
Sbjct: 1543 WLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Score = 63.7 bits (148), Expect = 6e-09
Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 23/206 (11%)
Query: 1306 LGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
+G P ++W H+ K +E A + + + G C + A+ +GI C A+N++G
Sbjct: 1683 IGDPTMVVEWLHDGKPLEAANRLRMINE-FGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1741
Query: 1366 TECIL-------------------NIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
T L ++ E + ++ E L+ T E+ P IV
Sbjct: 1742 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIV-LY 1800
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P V EG+ R + G P+P+V W G + +S +++ DG L + +
Sbjct: 1801 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKS 1858
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVE 1492
DTGE+ A N GV L ++
Sbjct: 1859 YDTGEVKVTAENPEGVIEHKVKLEIQ 1884
Score = 63.7 bits (148), Expect = 6e-09
Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 4/185 (2%)
Query: 1431 QVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALS 1490
QV W +L S +Y+I +DG +IL + ++ + D G + N G ++ A L
Sbjct: 25102 QVTWYFGVRQLENSEKYEIT-YEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELF 25160
Query: 1491 VESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNP 1550
V+ + +Y + ++ ++ + P F + + + E V F + +P
Sbjct: 25161 VKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 25220
Query: 1551 TPEILWYKDNKVIR---TDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
P + WYK + I+ D+++ E+ + TI T D + YT A + G K
Sbjct: 25221 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 25280
Query: 1608 AKLQV 1612
AKL V
Sbjct: 25281 AKLTV 25285
Score = 63.3 bits (147), Expect = 8e-09
Identities = 83/356 (23%), Positives = 134/356 (37%), Gaps = 48/356 (13%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
VL P+ + ++G+ + K++GRP P+ WFH+ + I + ++ G + I
Sbjct: 1414 VLKPV-SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV 1472
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
A P +G + A N+ G+ S IL +EA E+ + P V
Sbjct: 1473 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH-------------------QVKPMFV 1513
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTSILTMP 1462
+ L V EG + ++ +A G P P + WL+ ++ +I E G + L +
Sbjct: 1514 EKLKN-VNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1572
Query: 1463 EVYQDDTGEIVFEAYNHLGVTATIAALSVE-----------SIVGTQEYRKPEWVT---- 1507
D+ A N G T ++VE I+ YR E
Sbjct: 1573 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELE 1632
Query: 1508 --HM-------EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS--GNPTPEILW 1556
H+ EE K Q P F K++ R+ FE + G+PT + W
Sbjct: 1633 PLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEW 1692
Query: 1557 YKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D K + R + N+ + A G TC+A + G T A L V
Sbjct: 1693 LHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 62.9 bits (146), Expect = 1e-08
Identities = 59/214 (27%), Positives = 94/214 (43%), Gaps = 20/214 (9%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI- 1458
P++++ L V T GK R A G P+P++ W ++ E L ST ++ + L DG
Sbjct: 3193 PQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKE--EQLLSTGFKCKFLHDGQEYT 3249
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E + +D EA N GV T A+LSVE PE V+ +E+
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV---------PEVVSPDQEMPVY--- 3297
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P + + E + F+ SG ++ WY +K I+ F + E+
Sbjct: 3298 ---PPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3353
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A + EGTYT A + +G + A L +
Sbjct: 3354 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 60.9 bits (141), Expect = 4e-08
Identities = 54/197 (27%), Positives = 88/197 (44%), Gaps = 27/197 (13%)
Query: 1391 KTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
KT AP I K + V TT G+ +L + +G P P ++W R G EL+QS +Y++
Sbjct: 24027 KTKLTSGEAPGIRKEMKDV-TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 24085
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME 1510
D T LT+ Q+D G A N +G T + L +++ T ++ P + E
Sbjct: 24086 S-DGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---TPQFH-PGYPL-KE 24139
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFI 1570
+ A+ +T R+H +Y G P P + W+ K+++ E
Sbjct: 24140 KYYGAVGSTL------------RLH--------VMYIGRPVPAMTWFHGQKLLQNSENIT 24179
Query: 1571 IENKENRTTCTIKKATK 1587
IEN E+ T +K +
Sbjct: 24180 IENTEHYTHLVMKNVQR 24196
Score = 60.5 bits (140), Expect = 6e-08
Identities = 63/232 (27%), Positives = 97/232 (41%), Gaps = 29/232 (12%)
Query: 1381 VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V EE + + + +V A +KA T ++ EG+ + L+A G V+W+ G E
Sbjct: 26524 VHEEITKTSQASEEVRTHAE--IKAFSTQMSINEGQRLVLKANIAGAT--DVKWVLNGVE 26579
Query: 1441 LLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEY 1500
L S EY+ + LT+ + D G + T + + E IV Q Y
Sbjct: 26580 LTNSEEYRYG-VSGSDQTLTIKQASHRDEGIL------------TCISKTKEGIVKCQ-Y 26625
Query: 1501 RKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
+T +EL A P F+ + + ++E + V F SG P+PEI W+K+N
Sbjct: 26626 D----LTLSKELSDA-------PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNN 26674
Query: 1561 KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I I N + I+ A+ G YT KA + G A L V
Sbjct: 26675 LPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 59.7 bits (138), Expect = 1e-07
Identities = 32/123 (26%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G++TC ++ G V + ++ DAP ++ + + +G+ + C+I G P
Sbjct: 26608 GILTCISKTKEGIVKCQYDLTLSKEL---SDAPAFISQPRSQNINEGQNVLFTCEISGEP 26664
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I+WF N I + +++ISR ++ + + I+ A +G Y A N G+CS
Sbjct: 26665 SPEIEWFKNNLPISISSNVSISRSRN-VYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 26723
Query: 1370 LNI 1372
L +
Sbjct: 26724 LMV 26726
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 55.6 bits (128), Expect = 2e-06
Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
P+ Y+ + G E +GV+ T + E + + VT + A ++ +
Sbjct: 841 PDTYKSEAG---VEVKKEVGVSITGTTVREERFEVL--HGREAKVTETARVPAPVEIPVT 895
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT V + V E E VT E SG P+P + WY+++ I + F I +
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++A + G +TC AV++ G T L V
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 55.6 bits (128), Expect = 2e-06
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 10/132 (7%)
Query: 1492 ESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP-------ERVHEEEIVTFEA 1544
ES+ ++E + + EE+ A +K ++ F+KE P + V EE +
Sbjct: 4205 ESLKPSEEKEESSSESGTEEV-ATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLT 4263
Query: 1545 IYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKA-TKDLEGTYTCKAVSDIGL 1603
N E+ WY +NK++ +DE+F +N T I K T+D +G Y C+A++D G
Sbjct: 4264 TSITN-AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGK 4322
Query: 1604 AVTKAKLQVFQR 1615
T AKL V +R
Sbjct: 4323 TATSAKLTVVKR 4334
Score = 55.6 bits (128), Expect = 2e-06
Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 27/239 (11%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDW 1315
AEN G +++ + G+AP + +++ T GE L+C+I+GRP P I W
Sbjct: 24010 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 24069
Query: 1316 FH-NEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
+ ++LI++ + S ++ + +E E G+Y C A+N+ G+ T L ++A
Sbjct: 24070 YRFGKELIQSRKYKMSSDGRTHTLTVMTEE--QEDEGVYTCIATNEVGEVETSSKLLLQA 24127
Query: 1375 YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRW 1434
P L ++ V G +RL IG P P + W
Sbjct: 24128 ---TPQFHPGYPLKEKYYGAV-------------------GSTLRLHVMYIGRPVPAMTW 24165
Query: 1435 LRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
G +LLQ++E IE + T ++ + G+ + N G I + ++
Sbjct: 24166 F-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24223
Score = 55.6 bits (128), Expect = 2e-06
Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
GV TC A N G V TS +++ PL E G + L+ +GRP
Sbjct: 24104 GVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK----EKYYGAVGSTLRLHVMYIGRP 24159
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + WFH +KL++ + +ITI + + AG YK SN FG + + I
Sbjct: 24160 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAI 24217
Query: 1370 LNIE 1373
L++E
Sbjct: 24218 LDVE 24221
Score = 54.8 bits (126), Expect = 3e-06
Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMD---GERISLNCKILGRPWP 1311
A N GS+S S +V TCID P++ PLE T V+ G + L I G+P P
Sbjct: 20347 ARNAVGSISNP-SEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAP 20405
Query: 1312 KIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
I+W+ ++K ++T + + + L I IK+A +G Y+ N G S
Sbjct: 20406 TIEWYKDDKELQTNALVCV-ENTTDLASILIKDADRLNSGCYELKLRNAMGSAS 20458
Score = 53.6 bits (123), Expect = 7e-06
Identities = 75/338 (22%), Positives = 135/338 (39%), Gaps = 20/338 (5%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
+VL P E V++GE C++ G P PK++W+ N +LI ++ + + G+ + I
Sbjct: 1797 IVLYP-EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLDI 1853
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR- 1401
+ G K TA N G + L I+ E SV + E + P
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRR---APEPRPEFHVHEPGK 1910
Query: 1402 ---IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE-LDDGTS 1457
V+ + V TTE K + +A I +V + EL + + EE + +
Sbjct: 1911 LQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVP--EESEELRSKFKRRTEEGYYEAIT 1968
Query: 1458 ILTMPEVYQDDTGEIVFEAYNH--LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ + +D++ E + L T + +++ + P + EL +
Sbjct: 1969 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2028
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN-KVIRTDERFIIENK 1574
++A P + I + V + F G P PE WYK+ K+ R+D + +
Sbjct: 2029 MEA----PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2084
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+N I+ T + + KA++ G + A L V
Sbjct: 2085 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2122
Score = 52.4 bits (120), Expect = 2e-05
Identities = 56/243 (23%), Positives = 96/243 (39%), Gaps = 24/243 (9%)
Query: 1255 RAENFAGSVSTSG-SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKI 1313
+ EN G S S + ++ + AP L N V +L CK+ G P P +
Sbjct: 24403 KCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIV 24462
Query: 1314 DWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
W+ K +I I K G ++ I + A +Y+ A+NQ G S L +
Sbjct: 24463 KWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
E VP+ + P+ ++ + V G+++ ++ G P P +
Sbjct: 24523 E----VPA---------------KIHLPKTLEGM-GAVHALRGEVVSIKIPFSGKPDPVI 24562
Query: 1433 RWLRQGTELLQST-EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W ++G +L+ + YQ+ TS++ V + D G V A N G+ L V
Sbjct: 24563 TW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Query: 1492 ESI 1494
+
Sbjct: 24622 ADV 24624
Score = 51.6 bits (118), Expect = 3e-05
Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 5/109 (4%)
Query: 1510 EELQAALKATQSVPTF---VKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD 1566
EE+QA TQ P VK + V + A +G P P+I W K + +++ D
Sbjct: 7180 EEIQAV--DTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQD 7237
Query: 1567 ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+R IEN ++T TI + + GTY +AV+ G A ++ V +
Sbjct: 7238 KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286
Score = 50.8 bits (116), Expect = 5e-05
Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + +++ TV G +++G+P P+ +W+ N IE + I + +CE
Sbjct: 2030 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE-EDVLSDEK 1391
+ I++ E + A N G+ S+ L ++A + + E +DV++ EK
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEK 2142
Score = 50.8 bits (116), Expect = 5e-05
Identities = 65/278 (23%), Positives = 112/278 (40%), Gaps = 35/278 (12%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA---RDITISRQKSGLC 1338
P PL N T GE + I P P + W+ + + I+ + T K GL
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I + Y A N++G+ S + L + + P ++ +
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH---PPPTDSTLRP---------- 25298
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS- 1457
+ K L EG+ + E + GIP P ++W + G L S IE + +G
Sbjct: 25299 ---MFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPL--SLGPNIEIIHEGLDY 25353
Query: 1458 -ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI-VGTQEYR-KPEWVTHMEE--- 1511
L + + +DTG A N G T+ A L VE + QE++ K E H+++
Sbjct: 25354 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQID 25413
Query: 1512 ----LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAI 1545
+ L T+SVP + ++ E + E ++ A+
Sbjct: 25414 KTLRMAEILSGTESVP--LTQVAKEALREAAVLYKPAV 25449
Score = 49.6 bits (113), Expect = 1e-04
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 1510 EELQAALKATQSVPT-FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER 1568
E++ + +++V + F I R+ E VTF SG P P+I WYKD K I+ ER
Sbjct: 1231 EKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1290
Query: 1569 FIIE-NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ ++ R + I + EG YT A + G A+ KL V
Sbjct: 1291 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1335
Score = 49.6 bits (113), Expect = 1e-04
Identities = 43/113 (38%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDG-DAP-LVLAPL--ENTTVMDGERISLNC-KILGRP 1309
RA+N AG++S S E C D +AP +VL P + T+ G+ I LN ILG+P
Sbjct: 13852 RAKNTAGAISAPSES-TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKP 13910
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
PK W K I + DIT + IK A + AG Y TA+N FG
Sbjct: 13911 LPKSSWSKAGKDIRPS-DITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 48.4 bits (110), Expect = 2e-04
Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 17/206 (8%)
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
IG P V WL G L + ++ + G L Y D+G I A N G
Sbjct: 1683 IGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1741
Query: 1485 TIAALSVESIVG-TQEYRKPEW---VTHMEELQ--AALKATQSVPTFVKE-------IIP 1531
T A L V+ +E + PE + +EEL+ A A V T KE + P
Sbjct: 1742 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1801
Query: 1532 E--RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
E RV E E F +G P P++ WY + ++IR +RF + + + D
Sbjct: 1802 EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYD- 1860
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQVFQR 1615
G A + G+ K KL++ QR
Sbjct: 1861 TGEVKVTAENPEGVIEHKVKLEIQQR 1886
Score = 48.0 bits (109), Expect = 3e-04
Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 8/153 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLENTTVMDGERISLNCKILGR 1308
G T A+N AG S S VE ++ P+ + L+N + +G ++ + + G
Sbjct: 1480 GEWTVVAQNRAGRSSISVILTVE---AVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGN 1536
Query: 1309 PWPKIDWFHNEKLIETAR--DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P P I W N +I + I I K G + I + + Y TA N+ G+ +T
Sbjct: 1537 PNPDIVWLKNSDIIVPHKYPKIRIEGTK-GEAALKIDSTVSQDSAWYTATAINKAGRDTT 1595
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
C +N+E E+ E ++ T +E A
Sbjct: 1596 RCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIA 1627
Score = 47.6 bits (108), Expect = 4e-04
Identities = 22/70 (31%), Positives = 35/70 (50%)
Query: 1546 YSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAV 1605
+ G PTP + W+KDN ++ R E+ EN + TIK A ++ G Y K + G A+
Sbjct: 15674 FIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAI 15733
Query: 1606 TKAKLQVFQR 1615
+ V +
Sbjct: 15734 ETLNVIVLDK 15743
Score = 47.2 bits (107), Expect = 6e-04
Identities = 24/76 (31%), Positives = 38/76 (50%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V A SG P P I WYKD+K ++T+ +EN + + IK A + G Y K +
Sbjct: 20393 VKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 20452
Query: 1600 DIGLAVTKAKLQVFQR 1615
+G A ++Q+ +
Sbjct: 20453 AMGSASATIRVQILDK 20468
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/151 (25%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 1263 VSTSGSSIVEEQTCI-DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
V + +S+ EEQ + AP + +++G + C++ G P P + W +
Sbjct: 1016 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1075
Query: 1322 IETARDITISRQK-SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA-YEYVP 1379
+ T +S K +G C++ I F + AG Y N+ G+ S L EA YE +
Sbjct: 1076 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1135
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
+E + + T+ V+E P++ + P V
Sbjct: 1136 KSQQEMLYQTQVTAFVQE--PKVGETAPGFV 1164
Score = 46.4 bits (105), Expect = 0.001
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++E IG P+P + W++ G L Q+T +EE T +L + E +DD G+
Sbjct: 17829 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST-VLHIKEGNKDDFGKYTV 17887
Query: 1475 EAYNHLGVTAT 1485
A N G TAT
Sbjct: 17888 TATNSAG-TAT 17897
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV-----KALPTVVTTTEGKLIRLEAKAIGI 1427
E Y + S E +SD + V A +V K L T G+ ++++ IG
Sbjct: 15618 EEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGR 15677
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
P P V W + L Q+T E ++ S+LT+ + ++D G V + N G
Sbjct: 15678 PTPAVTWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAG 15730
Score = 45.6 bits (103), Expect = 0.002
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQK----SGLCEIHIKEAFP 1347
V GE + + + G P PKI+W NE +IE D + I++++ E+ I +A
Sbjct: 8913 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 8972
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
E G Y TASN+ G +++E Y+ PS ++D K
Sbjct: 8973 EDKGTYTVTASNRLGSVFRN--VHVEVYDR-PSPPRNLAVTDIK 9013
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 8/105 (7%)
Query: 1506 VTHMEELQAA----LKA-TQSVPTFVKEIIPE-RVHEEEIVTFEAIYSGNPTPEILWYKD 1559
+++M +L+++ LKA + +P ++ + + + E +++T ++G PTPE+ W
Sbjct: 26809 ISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG 26868
Query: 1560 NKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ I + E RF IEN ++ TT I K G YT ++ G
Sbjct: 26869 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL--LQSTEYQIEELDDGTS 1457
P ++ALP+ ++ EGK++ + G P P+V W G ++ + + IE DD T+
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 26890
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
++ M +V + D G N G + + + SI
Sbjct: 26891 LIIM-DVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 44.8 bits (101), Expect = 0.003
Identities = 50/215 (23%), Positives = 92/215 (42%), Gaps = 30/215 (13%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
AP+I + + + T +G + +G P P+ W + G ++ +S +D
Sbjct: 2031 APKIFERIQSQ-TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + +V +D+ I+ +A N G T++ A L V++ + +T +ELQ +
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA---------KQLITFTQELQDVV-- 2138
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
KE ++ + TFE + P ++ WYKD + +++ + +
Sbjct: 2139 -------AKE-------KDTMATFEC-ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVH 2183
Query: 1579 TCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+I T D E Y+C V D + T AKL V
Sbjct: 2184 FLSILTIDTSDAE-DYSCVLVEDENVKTT-AKLIV 2216
Score = 44.8 bits (101), Expect = 0.003
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G +R A G+P P +W G+E+ Y + E D+ +S+LT+ + DTGE
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV-ETDNFSSVLTIKNCLRRDTGEYQI 11086
Query: 1475 EAYNHLGVTATIAALSVESIVG 1496
N G L+V + G
Sbjct: 11087 TVSNAAGSKTVAVHLTVLDVPG 11108
Score = 44.8 bits (101), Expect = 0.003
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Query: 1405 ALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEV 1464
AL T V G+ +++ G P P V W + L Y IE D +S+LT+P+V
Sbjct: 20779 ALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS-SSLLTIPQV 20837
Query: 1465 YQDDTGEIVFEAYNHLG 1481
++DTG+ + N +G
Sbjct: 20838 TRNDTGKYILTIENGVG 20854
Score = 44.8 bits (101), Expect = 0.003
Identities = 22/75 (29%), Positives = 37/75 (49%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E + +A+ G P P + W+KD I I + T+ ++ AT+D G YT +A
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEA 21536
Query: 1598 VSDIGLAVTKAKLQV 1612
+ G A + K++V
Sbjct: 21537 KNASGSAKAEIKVKV 21551
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/63 (30%), Positives = 33/63 (52%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+I WY+ K + ++ + + T T+ ++ EG YTC A +++G T
Sbjct: 24061 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 24120
Query: 1608 AKL 1610
+KL
Sbjct: 24121 SKL 24123
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I+ +P +T GK +R+EA G P P +W + E++ S+ + + D +SIL
Sbjct: 12403 PKIL--MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKA-DSSSIL 12459
Query: 1460 TMPEVYQDDTGEIVFEAYNHLG 1481
+ +V + D+G A N G
Sbjct: 12460 IIKDVTRKDSGYYSLTAENSSG 12481
Score = 44.0 bits (99), Expect = 0.005
Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 6/134 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
V+++ ++D G C A N +G +TS V ++ AP++ +E V G
Sbjct: 4299 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA-----APVIKRKIEPLEVALGHL 4353
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
C+I P + WF + I + +I R + + I G Y C AS
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 4412
Query: 1359 NQFGKCSTECILNI 1372
N++G S L +
Sbjct: 4413 NEYGSVSCTATLTV 4426
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+V G I++E +G PKP V W ++G ++L+ T+ E ++IL + E + D
Sbjct: 14577 LVIAKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSD 14635
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVG 1496
+G A N +G + + V I G
Sbjct: 14636 SGPYPLTARNIVGEVGDVITIQVHDIPG 14663
Score = 44.0 bits (99), Expect = 0.005
Identities = 18/57 (31%), Positives = 31/57 (54%)
Query: 1546 YSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ G P P + W KD K + +D R+ IEN ++ + TI + T++ G Y + +G
Sbjct: 20798 FKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854
Score = 43.6 bits (98), Expect = 0.007
Identities = 48/226 (21%), Positives = 85/226 (37%), Gaps = 26/226 (11%)
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I D P++ PL +T +G+ + L I +++W+ KL+ + + ++
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA--KEVNWYFENKLVPSDEKFKCLQDQNT 4295
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ K + G Y C A N GK +T L + V+
Sbjct: 4296 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV----------------------VK 4333
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
AP ++K + G L + + P + +W + G E+ +S + I
Sbjct: 4334 RAAP-VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS-SKYI 4391
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRK 1502
S L + D GE +A N G + A L+V G ++ RK
Sbjct: 4392 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRK 4437
Score = 43.2 bits (97), Expect = 0.009
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTC---K 1596
V E Y G P P I W KD ++ E EN+ T +IK A K+ G YT
Sbjct: 21084 VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN 21143
Query: 1597 AVSDIGLAVT 1606
AV I + +T
Sbjct: 21144 AVCRIAVPIT 21153
Score = 42.7 bits (96), Expect = 0.012
Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 5/136 (3%)
Query: 1232 QPLKALNV-LEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLE 1289
+P+K L +EE + D V+ RA N G + S I E D D P +
Sbjct: 7840 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGV--SEPSEISENVVAKDPDCKPTIDLETH 7897
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
+ V++GE++S+ P P + W + K ++ + +T+ + + ++
Sbjct: 7898 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS-AHLEVPKSVRAD 7956
Query: 1350 AGIYKCTASNQFGKCS 1365
AGIY T N+ G +
Sbjct: 7957 AGIYTITLENKLGSAT 7972
Score = 42.7 bits (96), Expect = 0.012
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 9/131 (6%)
Query: 1368 CILNIEAYEYVPSVSEEDVLSD-EKTSDV---EEFA-PRIVKALPTVVTTTEGKLIRLEA 1422
C+ N + YE+ E SD KT +V E+ P + L V+T G IRLEA
Sbjct: 11668 CVEN-QIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEA 11726
Query: 1423 KAIGIPKPQVRWL--RQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHL 1480
G P P+V W + T+L +S +I+ D +S ++ + + D G+ V A N
Sbjct: 11727 GVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD-SSKFSLTKAKRSDGGKYVVTATNTA 11785
Query: 1481 GVTATIAALSV 1491
G A ++V
Sbjct: 11786 GSFVAYATVNV 11796
Score = 42.7 bits (96), Expect = 0.012
Identities = 21/68 (30%), Positives = 30/68 (44%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P I W KD + ++ R +E T IK+ KD G YT A + G A
Sbjct: 17840 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATEN 17899
Query: 1608 AKLQVFQR 1615
+ V ++
Sbjct: 17900 LSVIVLEK 17907
Score = 42.7 bits (96), Expect = 0.012
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLV-LAP--LENTTVMDGERISLNCKILGRPWPK 1312
A N G++S S T + P+V P + + GE + + + GRP P+
Sbjct: 21433 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21492
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ WF + IE ++ I+ G + +++A + G+Y A N G E + +
Sbjct: 21493 VTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Query: 1373 E 1373
+
Sbjct: 21552 Q 21552
Score = 42.3 bits (95), Expect = 0.016
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV G + L+ + G+P P + W + L++ A I ++ Q++ LC + + + +G
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDSG 12867
Query: 1352 IYKCTASNQFGKCSTECILNI 1372
Y TA N G S L +
Sbjct: 12868 DYTITAENSSGSKSATIKLKV 12888
Score = 41.9 bits (94), Expect = 0.022
Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++E G PKP + W + G L Q+T + + D T+ L++ E ++DD G+
Sbjct: 16747 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT-LSIKETHKDDGGQYGI 16805
Query: 1475 EAYNHLG-VTATIAALSVE 1492
N +G TA+I ++++
Sbjct: 16806 TVANVVGQKTASIEIVTLD 16824
Score = 41.9 bits (94), Expect = 0.022
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + P ++ GE + + ++GRP P I W + + ++ + + + +H
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV-LH 17873
Query: 1342 IKEAFPEMAGIYKCTASNQFG 1362
IKE + G Y TA+N G
Sbjct: 17874 IKEGNKDDFGKYTVTATNSAG 17894
Score = 41.5 bits (93), Expect = 0.029
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
V+ G+++++ A G P P + W + G E+ + +I D+ T +LT+ + + D
Sbjct: 19301 VIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT-LLTVKDCIRRD 19359
Query: 1469 TGEIVFEAYNHLGVTATIA 1487
TG+ V N G T ++A
Sbjct: 19360 TGQYVLTLKNVAG-TRSVA 19377
Score = 41.1 bits (92), Expect = 0.038
Identities = 40/173 (23%), Positives = 75/173 (43%), Gaps = 11/173 (6%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSS--IVEEQTCIDGDAPLVLAPL 1288
I +K L + N+++ A N AG + S IV+EQT + L L +
Sbjct: 14517 ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP---ELDLRGI 14573
Query: 1289 ENTTVMD--GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
V+ G+ I + +LGRP P + W +++++ + + + ++I E
Sbjct: 14574 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECV 14632
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+G Y TA N G+ ++ I+ ++ +P + DE +SD F+
Sbjct: 14633 RSDSGPYPLTARNIVGEVGD--VITIQVHD-IPGPPTGPIKFDEVSSDFVTFS 14682
Score = 41.1 bits (92), Expect = 0.038
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGT 1592
VH E EA G P P+++W KD K + T R I++ +TT +K + G
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 1593 YTCKAVSDIG 1602
Y K +S++G
Sbjct: 18282 YILK-LSNVG 18290
Score = 41.1 bits (92), Expect = 0.038
Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 6/119 (5%)
Query: 1379 PSVSEEDVLS-DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
PS S +++ DE + EF P L G+ +R++A G P P+V W +
Sbjct: 21443 PSQSSGIIMTRDENVPPIVEFGPEYFDGL----IIKSGESLRIKALVQGRPVPRVTWFKD 21498
Query: 1438 GTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
G E+ + +I ++ TS L + + +D G EA N G + V+ G
Sbjct: 21499 GVEIEKRMNMEITDVLGSTS-LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556
Score = 41.1 bits (92), Expect = 0.038
Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
EY S++E + + + D+E + L VT G +RL G P P + W
Sbjct: 22930 EYSESIAEIEPVERIEIPDLE-----LADDLKKTVTIRAGASLRLMVSVSGRPPPVITWS 22984
Query: 1436 RQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIV 1495
+QG +L I + + S+L + +V + D G+ EA N G + + V
Sbjct: 22985 KQGIDLASRA---IIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTP 23041
Query: 1496 G 1496
G
Sbjct: 23042 G 23042
Score = 40.3 bits (90), Expect = 0.066
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR--TDERFI----IENKENRTTCTIKKAT 1586
+V E V A +G P P+I W K+ VI TD I + E +T +I KA
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
++ +GTYT A + +G ++V+ R
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDR 9000
Score = 39.9 bits (89), Expect = 0.087
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T G I L A G P+P++ W + L Q IE + S +T+ + + DT
Sbjct: 7203 LTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK-KSTVTIVDSKRSDT 7261
Query: 1470 GEIVFEAYNHLGVTATIAALSV 1491
G + EA N G + ++V
Sbjct: 7262 GTYIIEAVNVCGRATAVVEVNV 7283
Score = 39.9 bits (89), Expect = 0.087
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G+ RLEA G P P + WLR E+ +S +I+ D ++L + + + D
Sbjct: 17138 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN-TDFKALLIVKDAIRIDG 17196
Query: 1470 GEIVFEAYNHLG 1481
G+ + A N G
Sbjct: 17197 GQYILRASNVAG 17208
Score = 39.9 bits (89), Expect = 0.087
Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 2/120 (1%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
+++ D V RA N GSVS + S VE I P L + + GE +S+
Sbjct: 24494 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH--LPKTLEGMGAVHALRGEVVSIK 24551
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
G+P P I W + LI+ + +S + + AG Y A N+FG
Sbjct: 24552 IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24611
Score = 39.5 bits (88), Expect = 0.12
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRI--VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
++S SD T E PRI A+ +++T G + L+A G P P V W +
Sbjct: 12776 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 12835
Query: 1438 GTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
GT LL+ E + L + V + D+G+ A N G + L V
Sbjct: 12836 GT-LLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 12888
Score = 39.5 bits (88), Expect = 0.12
Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
T + G P P +LW K + +RT R ++ ++RT+ TI+ A ++ G YT
Sbjct: 19708 TMTVPFRGRPVPNVLWSKPDTDLRT--RAYVDTTDSRTSLTIENANRNDSGKYT 19759
Score = 39.1 bits (87), Expect = 0.15
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 1513 QAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE 1572
+A L + P F ++ E++ V + S P + W+KD K I+ + +I+
Sbjct: 5511 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIK 5569
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ +KKA K G YTC D G T KL + R
Sbjct: 5570 ADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 5608
Score = 39.1 bits (87), Expect = 0.15
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 1544 AIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGL 1603
A+ +G P P +W K+ + D R +I+N ++ IK A + G Y A + G
Sbjct: 8629 AVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGS 8687
Query: 1604 AVTKAKLQVF 1613
A+++VF
Sbjct: 8688 KFAAARVEVF 8697
Score = 39.1 bits (87), Expect = 0.15
Identities = 22/73 (30%), Positives = 28/73 (38%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V F AI G P P W D I+TDE + +E + TIK + G Y +
Sbjct: 11031 VRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSN 11090
Query: 1600 DIGLAVTKAKLQV 1612
G L V
Sbjct: 11091 AAGSKTVAVHLTV 11103
Score = 39.1 bits (87), Expect = 0.15
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTMPEVYQD 1467
V+T G+ IR+ A+ G P+P + W ++G L++ E +++ + D + L + E +
Sbjct: 11420 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR--EKRVDLIQDLPRVELQIKEAVRA 11477
Query: 1468 DTGEIVFEAYNHLGVTATIAALSV 1491
D G+ + A N G A ++V
Sbjct: 11478 DHGKYIISAKNSSGHAQGSAIVNV 11501
Score = 39.1 bits (87), Expect = 0.15
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV G+ I + ++ GRP P I W K++ + + + Q E+ IKEA G
Sbjct: 11422 TVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLI-QDLPRVELQIKEAVRADHG 11480
Query: 1352 IYKCTASNQFGKCSTECILNI 1372
Y +A N G I+N+
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV 11501
Score = 39.1 bits (87), Expect = 0.15
Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRI---VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLR 1436
++S SD T + AP+I VK TV+ G+ RLEA G P P + W +
Sbjct: 14942 AISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKA-GEAFRLEADVSGRPPPTMEWSK 15000
Query: 1437 QGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
G EL + + +I+ D T+++ + D+G A N G I + V G
Sbjct: 15001 DGKELEGTAKLEIKIADFSTNLVNKDST-RRDSGAYTLTATNPGGFAKHIFNVKVLDRPG 15059
Query: 1497 TQE 1499
E
Sbjct: 15060 PPE 15062
Score = 39.1 bits (87), Expect = 0.15
Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 16/195 (8%)
Query: 1366 TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL-------PTVVTTTEGKLI 1418
TE ++ +YE+ S + +EK+ + + +I L P +T EG+
Sbjct: 26022 TETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESA 26081
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
R G P P V WLR+G L S +Q+ S + V D G N
Sbjct: 26082 RFSCDTDGEPVPTVTWLRKGQVLSTSARHQV-TTTKYKSTFEISSVQASDEGNYSVVVEN 26140
Query: 1479 HLGVTATIAALSVESIVGTQE-YRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
G L+++ T++ P V E + +A +S P VK PE H +
Sbjct: 26141 SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKS-PKRVKS--PEPSHPK 26197
Query: 1538 EIVTFEAIYSGNPTP 1552
+ E PTP
Sbjct: 26198 AVSPTET----KPTP 26208
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P V P V E++ ++ GRP ++W + + ++ + +S K+ + +
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKT-VTSLS 18956
Query: 1342 IKEAFPEMAGIYKCTASNQFG 1362
IKEA E G Y+ SN G
Sbjct: 18957 IKEASKEDVGTYELCVSNSAG 18977
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/114 (18%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDIT 1329
++ +Q AP + + + V G+ + +P ++ W+HN ++ + I
Sbjct: 25865 VLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH 25924
Query: 1330 ISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE 1383
+ SG+ + I + + +G Y+ +N G+ S L++ +Y S+
Sbjct: 25925 YTNT-SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQ 25977
Score = 38.3 bits (85), Expect = 0.27
Identities = 21/90 (23%), Positives = 38/90 (42%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT E V E E ++ + P P + W+KD K ++ +R ++N +
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 7949
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K+ + G YT + +G A ++V
Sbjct: 7950 PKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 37.9 bits (84), Expect = 0.35
Identities = 22/82 (26%), Positives = 36/82 (43%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
VH E +A G P P I W K ++ + R I++ + T+ ++K A + G Y
Sbjct: 16058 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNY 16117
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
KA + G ++V R
Sbjct: 16118 ILKAKNVAGERSVTVNVKVLDR 16139
Score = 37.9 bits (84), Expect = 0.35
Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ +++A G P P ++W++ EL + +I+ D TS L++ + + D+G +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS-LSVKDAVRVDSGNYIL 16119
Query: 1475 EAYNHLGVTATIAALSVESIVGTQE 1499
+A N G + + V G E
Sbjct: 16120 KAKNVAGERSVTVNVKVLDRPGPPE 16144
Score = 37.5 bits (83), Expect = 0.47
Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 10/146 (6%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKID 1314
+A N AG + S+ V C D P + E V +G +++ KI G P+P +
Sbjct: 9595 KAVNAAGV--SKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLT 9652
Query: 1315 WFH-NEKLIETARDITISRQKSGL-----CEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
WF K + + + L C + I ++ G+Y TA N G S E
Sbjct: 9653 WFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEM 9712
Query: 1369 ILNIEAYEYVP--SVSEEDVLSDEKT 1392
LN+ P + E V +D+ T
Sbjct: 9713 RLNVLGRPGPPVGPIKFESVSADQMT 9738
Score = 37.5 bits (83), Expect = 0.47
Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+++I RV + + A G P P+I W K+ KV+ ++R + R IK+A
Sbjct: 11418 RDVITVRVGQT--IRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAV 11475
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ G Y A + G A A + V R
Sbjct: 11476 RADHGKYIISAKNSSGHAQGSAIVNVLDR 11504
Score = 37.5 bits (83), Expect = 0.47
Identities = 22/65 (33%), Positives = 29/65 (44%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+ W K K IR + I + + TIK AT+ G YT A + G V
Sbjct: 13908 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 13967
Query: 1608 AKLQV 1612
K+ V
Sbjct: 13968 VKVTV 13972
Score = 37.1 bits (82), Expect = 0.61
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLE--NTTVMD-GERISLNCKILGRPWP 1311
A+N AG++S S + TC D +AP + ++ +T ++ GE L + GRP P
Sbjct: 14936 AKNAAGAISPP-SEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPP 14994
Query: 1312 KIDWFHNEKLIE-TAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
++W + K +E TA+ +I I+ + L K++ +G Y TA+N G + I
Sbjct: 14995 TMEWSKDGKELEGTAKLEIKIADFSTNLVN---KDSTRRDSGAYTLTATNPGG--FAKHI 15049
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSD 1394
N++ + P E + E TS+
Sbjct: 15050 FNVKVLDR-PGPPEGPLAVTEVTSE 15073
Score = 37.1 bits (82), Expect = 0.61
Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 7/109 (6%)
Query: 1288 LENT-TVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDITISRQKSGLCEIHIKEA 1345
L NT TV+ GE + ++ +GRP P + W N L +T R S + + L + IK+A
Sbjct: 15656 LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSL--LTIKDA 15713
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
E G Y +N G+ LN+ + P V DE T+D
Sbjct: 15714 CREDVGHYVVKLTNSAGEAIE--TLNVIVLD-KPGPPTGPVKMDEVTAD 15759
Score = 37.1 bits (82), Expect = 0.61
Identities = 19/60 (31%), Positives = 28/60 (46%)
Query: 1543 EAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E SG P P I W KD ++ R + + + TT +IK+ KD G Y + +G
Sbjct: 16753 EVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG 16812
Score = 37.1 bits (82), Expect = 0.61
Identities = 19/82 (23%), Positives = 36/82 (43%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E + + + G P + W KD + ++ R + + + T+ +IK+A+K+ GTY
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
+ G + V R
Sbjct: 18969 ELCVSNSAGSITVPITIIVLDR 18990
Score = 36.7 bits (81), Expect = 0.81
Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ----KSGLCEI 1340
++PLE+ TV +GE + C+ L + WF N+ + T+R + IS + K + E+
Sbjct: 5080 MSPLEDQTVKEGETATFVCE-LSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEV 5138
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
+ + A + + +++ Q + ++ ++ +E L E + DV
Sbjct: 5139 TLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDV 5193
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/78 (29%), Positives = 33/78 (42%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E EA SG P P + W KD K + + I+ + T K +T+ G YT A
Sbjct: 14980 EAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTA 15039
Query: 1598 VSDIGLAVTKAKLQVFQR 1615
+ G A ++V R
Sbjct: 15040 TNPGGFAKHIFNVKVLDR 15057
Score = 36.7 bits (81), Expect = 0.81
Identities = 18/75 (24%), Positives = 33/75 (44%)
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
T + SG P P++ W + ++ +R I ++RTT T+K + + G Y +
Sbjct: 22169 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22228
Query: 1601 IGLAVTKAKLQVFQR 1615
G+ + V R
Sbjct: 22229 AGVKTFSVTVVVIGR 22243
Score = 36.3 bits (80), Expect = 1.1
Identities = 40/205 (19%), Positives = 80/205 (39%), Gaps = 9/205 (4%)
Query: 1525 FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKK 1584
F++ + +V E+E+ FE S ++ W+KD I+ +++ I +K I K
Sbjct: 5879 FLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937
Query: 1585 ATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXXXXXXXXXXXXXXXXXXXXEEESVGV 1644
D E Y+C ++ A T L V + E S
Sbjct: 5938 CLLDDEAEYSC----EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPG 5993
Query: 1645 EDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSESEHIETEDIALQKKVDEKTKG-IPV 1703
+ + + E+ + + +KR I+V ++ H+E + +T G + V
Sbjct: 5994 AEVIWYKGDEEIIETGRYEILTEGRKR---ILVIQNAHLEDAGNYNCRLPSSRTDGKVKV 6050
Query: 1704 EEKAKPILTTHEHVVLSEQQEGESV 1728
E A ++ +++ + E ++ E V
Sbjct: 6051 HELAAEFISKPQNLEILEGEKAEFV 6075
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A L +V FVKE+ V E E I S E WY ++ ++++ ++ I +
Sbjct: 2212 AKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKYTITS 2270
Query: 1574 KENRTTCTIKKATKDLEGTYT 1594
+ R T+K TK+ +G Y+
Sbjct: 2271 RRGRQNLTVKDVTKEDQGEYS 2291
Score = 35.9 bits (79), Expect = 1.4
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A LK ++ P F ++ + E++ +T + S + P + W+KD + I ++ I+
Sbjct: 5157 AQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VP-VKWFKDGEEIVPSPKYSIKA 5214
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
R IKKA +G Y C D G TKA + V R
Sbjct: 5215 DGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEAR 5252
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKID 1314
RAEN AG +S + + DAP V+ + V G+ I+L+ I G P+P I
Sbjct: 8158 RAENAAG-ISEPSRATPPTKAVDPIDAPKVILRT-SLEVKRGDEIALDASISGSPYPTIT 8215
Query: 1315 WFHNEKLI 1322
W +E +I
Sbjct: 8216 WIKDENVI 8223
Score = 35.9 bits (79), Expect = 1.4
Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
Query: 1415 GKLIRLEAKAIGIPKPQVRW------LRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
G+ + + A G+P P++ W + + T+ LQ T+ ++ + T L++P+ ++D
Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE-LSIPKAVRED 8974
Query: 1469 TGEIVFEAYNHLG 1481
G A N LG
Sbjct: 8975 KGTYTVTASNRLG 8987
Score = 35.9 bits (79), Expect = 1.4
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ +A G P P+I+W K +K + E+ ++ R T IK + G YT +
Sbjct: 22568 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22627
Query: 1600 DIGLAVTKAKLQV 1612
G ++V
Sbjct: 22628 ASGTKAVSVMVKV 22640
Score = 35.5 bits (78), Expect = 1.9
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 10/120 (8%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
++ PL++T V + + + NC++ K WF NE+ I + I QK + + I+
Sbjct: 6145 IVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIR 6202
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
+A + Y + +N G+ + + N+ V EED+ E D+E + V
Sbjct: 6203 DAHLDDQANYNVSLTNHRGE-NVKSAANL-------IVEEEDLRIVEPLKDIETMEKKSV 6254
Score = 35.1 bits (77), Expect = 2.5
Identities = 19/76 (25%), Positives = 31/76 (40%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V +A G P P + W KD +++ E + + N T + + G YT A +
Sbjct: 12816 VCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 12875
Query: 1600 DIGLAVTKAKLQVFQR 1615
G KL+V +
Sbjct: 12876 SSGSKSATIKLKVLDK 12891
Score = 35.1 bits (77), Expect = 2.5
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 4/113 (3%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLV-LAP-LENTTVMD-GERISLNCKILGRPWPK 1312
A+N AG++S S + + P + + P +T V++ GE L + G+P P
Sbjct: 17100 AKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPT 17159
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
I+W +K IE + I I +K+A G Y ASN G S
Sbjct: 17160 IEWLRGDKEIEESARCEIKNTDFKALLI-VKDAIRIDGGQYILRASNVAGSKS 17211
Score = 34.7 bits (76), Expect = 3.3
Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Query: 1255 RAENFAG--SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
+A+N AG + SS++ ++ I+ A L + T G +++ I GRP PK
Sbjct: 22122 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22181
Query: 1313 IDWFHNE-KLIETAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
+ W E +L ET R IT ++ ++ L +K++ +G Y T N G
Sbjct: 22182 VTWKLEEMRLKETDRVSITTTKDRTTLT---VKDSMRGDSGRYFLTLENTAG 22230
Score = 34.3 bits (75), Expect = 4.3
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L TV G +I L + G+P PKI W + +++ + ITI + I ++
Sbjct: 7200 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK-KSTVTIVDSKR 7258
Query: 1348 EMAGIYKCTASNQFGKCSTECILNI 1372
G Y A N G+ + +N+
Sbjct: 7259 SDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 34.3 bits (75), Expect = 4.3
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKV--IRTDERFIIENKENRTTCTIKKATKDLEGTYTC 1595
+ + EA G P PE+ W KD + R I+ + + + ++ KA + G Y
Sbjct: 11720 DTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVV 11779
Query: 1596 KAVSDIGLAVTKAKLQVFQR 1615
A + G V A + V +
Sbjct: 11780 TATNTAGSFVAYATVNVLDK 11799
Score = 34.3 bits (75), Expect = 4.3
Identities = 22/82 (26%), Positives = 34/82 (41%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V+ E EA G P P I W + +K I R I+N + + +K A + G Y
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199
Query: 1594 TCKAVSDIGLAVTKAKLQVFQR 1615
+A + G ++V R
Sbjct: 17200 ILRASNVAGSKSFPVNVKVLDR 17221
Score = 33.9 bits (74), Expect = 5.7
Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E +L + A + VSE +S+ + + P I ++ EG+ + +
Sbjct: 7858 EYVLRVRAVNAI-GVSEPSEISENVVAKDPDCKPTIDLETHDIIVI-EGEKLSIPVPFRA 7915
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG-VTAT 1485
+P P V W + G E+ S ++ D ++ L +P+ + D G N LG TA+
Sbjct: 7916 VPVPTVSWHKDGKEVKASDRLTMKN-DHISAHLEVPKSVRADAGIYTITLENKLGSATAS 7974
Query: 1486 I 1486
I
Sbjct: 7975 I 7975
Score = 33.9 bits (74), Expect = 5.7
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G+ + L+ I G P+PK+ W ++ T I ++ S ++ I+ A E GIY
Sbjct: 10736 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS---KLEIRNAAHEDGGIYSL 10792
Query: 1356 TASNQFG 1362
T N G
Sbjct: 10793 TVENPAG 10799
Score = 33.9 bits (74), Expect = 5.7
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 6/111 (5%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM---DGERISLNCKILGRPWPK 1312
A N A SVS S D + P V+ ++ V+ GE + +N I GRP P
Sbjct: 19264 ARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV 19323
Query: 1313 IDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
I W + ++ E AR IS L + +K+ G Y T N G
Sbjct: 19324 ISWAKDGIEIEERARTEIISTDNHTL--LTVKDCIRRDTGQYVLTLKNVAG 19372
Score = 33.5 bits (73), Expect = 7.6
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD------DGTSILTMPEVYQD 1467
EG + + AK G+P P + W + + + E + + D T L +P+ +
Sbjct: 9633 EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 9692
Query: 1468 DTGEIVFEAYNHLGVTATIAALSV 1491
DTG A N+LG + L+V
Sbjct: 9693 DTGLYTITAVNNLGTASKEMRLNV 9716
Score = 33.5 bits (73), Expect = 7.6
Identities = 15/47 (31%), Positives = 20/47 (42%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
G P P + W K + TD R +E+ TT + K G YT
Sbjct: 13511 GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYT 13557
Score = 33.5 bits (73), Expect = 7.6
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
E++ A +G P P I W KD I R I + +N T T+K + G Y
Sbjct: 19308 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQY 19363
Score = 33.5 bits (73), Expect = 7.6
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVF 1474
G+ + L G P P W G++L +S +E + LT+ E DTGE
Sbjct: 23256 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVET-HTKVAKLTIRETTIRDTGEYTL 23314
Query: 1475 EAYNHLGVTA 1484
E N G T+
Sbjct: 23315 ELKNVTGTTS 23324
>AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.
Length = 5604
Score = 97.9 bits (233), Expect = 3e-19
Identities = 69/235 (29%), Positives = 108/235 (45%), Gaps = 25/235 (10%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P +++ L+N TV++GE ++L C I G P P + W+ + IE++ D I+ Q SG+ +
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-SGIARLM 1001
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE-------------------YVPS-- 1380
I+EAF E +G + C+A N+ G ST C L ++ E +V S
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061
Query: 1381 -VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
V + L++E+ E AP + P V EG + + G PKP V W + G
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFI-TKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 1440 ELLQSTEYQIE-ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L Y++ G L + + DD GE N G T+ A+L E+
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175
Score = 89.4 bits (212), Expect = 1e-16
Identities = 64/214 (29%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P VL L+ TV G+ I GRP PKI W+ E+L+ T
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I EAFPE A +Y C A N +G +T L++E VP V D ++ +
Sbjct: 3297 LLI-EAFPEDAAVYTCEAKNDYGVATTSASLSVE----VPEVVSPD-------QEMPVYP 3344
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P I+ L V T+EG+ R + + G +V W + ++ S +++ + +D T L
Sbjct: 3345 PAIITPLQDTV-TSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQL 3401
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
+ E Y +D G F A N +G ++ A LS+E+
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435
Score = 74.9 bits (176), Expect = 3e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 74.1 bits (174), Expect = 4e-12
Identities = 77/331 (23%), Positives = 131/331 (39%), Gaps = 47/331 (14%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + PL V + + ++ G P P + W+ N+ L+E I + R +C +
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMER-VGNVCSLE 5241
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
I G Y C A N G+ S + D++ E+ R
Sbjct: 5242 ISNIQKGEGGEYMCHAVNIIGEAK--------------SFANVDIMPQEE---------R 5278
Query: 1402 IVKALPTVVTTTEGKLIRLE-AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+V ALP VT LE + P PQ L ++ +E ++E + I+T
Sbjct: 5279 VV-ALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLE-----VELSEKDVKEFEKQVKIVT 5332
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+PE D H + ++ L + + R+ E +EL+ L+ +
Sbjct: 5333 VPEFTPD-----------HKSMIVSLDVLPFNFVDPNMDSREGE----DKELKIDLEVFE 5377
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE-RFIIENKENRTT 1579
P F+ I ++ E F+ G PTPE+ WYK+ I D +++I ++ T
Sbjct: 5378 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 5437
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
I+ TY C+AV+ +G A+ + L
Sbjct: 5438 LKIRNVCLSDSATYRCRAVNCVGEAICRGFL 5468
Score = 68.1 bits (159), Expect = 3e-10
Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDA------PLVLAPLENTTVMDGERISLNCK 1304
V TC A+N G +TS S VE + D P ++ PL++T +G+ C+
Sbjct: 3308 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR 3367
Query: 1305 ILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
+ G K+ W+ +K I+ +R ++ Q ++ I EA+PE G Y ASN G+
Sbjct: 3368 VSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 3425
Query: 1365 STECILNIEAYEYV 1378
S+ L++EA E +
Sbjct: 3426 SSTANLSLEAPESI 3439
Score = 67.3 bits (157), Expect = 5e-10
Identities = 78/361 (21%), Positives = 139/361 (38%), Gaps = 31/361 (8%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +V L V T EG+ + LE G P P V W R+ ++ S ++QI G + L
Sbjct: 943 PTLVSGLKNV-TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQIT-FQSGIARL 1000
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSV--------ESIVGTQEYRKPE--WVTHM 1509
+ E + +D+G A N G +T L+V E+ T+++ E +V
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 1510 EELQAALKATQ--------SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNK 1561
+ + T+ + P F+ + + +++ E V F GNP P + W K
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 1562 VIRTDERFIIENKENRTTC--TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXX 1619
+ T R+ + + C I D G YT + G A L + +
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADYEL 1179
Query: 1620 XXXXXXXXXXXXXXXXXXEEESVGVEDTLDFATVSEVQALDKQHSTDKVKKRKAKIVVSE 1679
+E VG E F + +K+ + ++K+ AK V
Sbjct: 1180 LMKSQQEMLYQTQVTAFVQEPKVG-ETAPGFVYSEYEKEYEKEQAL--IRKKMAKDTVVV 1236
Query: 1680 SEHIETEDIALQKKVDEKTKGIPVEEKAKPILTTHEHVVLSEQQEGESVEPFDESYQTQK 1739
++E ++ + + K E + + I TT E ++ + +E +V+ ES +
Sbjct: 1237 RTYVEDQEFHISSFEERLIK----EIEYRIIKTTLEELLEEDGEEKMAVD-ISESEAVES 1291
Query: 1740 G 1740
G
Sbjct: 1292 G 1292
Score = 66.9 bits (156), Expect = 7e-10
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G PTP + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 64.5 bits (150), Expect = 4e-09
Identities = 76/359 (21%), Positives = 131/359 (36%), Gaps = 42/359 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
++N +++G ++ +CK+ G P PKI W+ + K I+ + + G + I P
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLP 1356
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
E GIY ASN G L +E P + + + E S + +PR V P
Sbjct: 1357 EDEGIYTAFASNIKGNAICSGKLYVE--PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSP 1414
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL-------- 1459
++ R+ + + + G L ++ E Q+E L +L
Sbjct: 1415 IRMSPARMSPARMSPARMSPAR-----MSPGRRLEETDESQLERLYKPVFVLKPVSFKCL 1469
Query: 1460 --------------TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
MPE + G+ + Y H V S+ IV EW
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL-IIVPATPSDSGEW 1528
Query: 1506 VTHMEE----------LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEIL 1555
+ L Q P FV+++ + E + + +GNP P+I+
Sbjct: 1529 TVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIV 1588
Query: 1556 WYKDNKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
W K++ +I + + IE + I YT A++ G T+ K+ V
Sbjct: 1589 WLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 63.7 bits (148), Expect = 6e-09
Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 23/206 (11%)
Query: 1306 LGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
+G P ++W H+ K +E A + + + G C + A+ +GI C A+N++G
Sbjct: 1729 IGDPTMVVEWLHDGKPLEAANRLRMINE-FGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 1366 TECIL-------------------NIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
T L ++ E + ++ E L+ T E+ P IV
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIV-LY 1846
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
P V EG+ R + G P+P+V W G + +S +++ DG L + +
Sbjct: 1847 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKS 1904
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVE 1492
DTGE+ A N GV L ++
Sbjct: 1905 YDTGEVKVTAENPEGVIEHKVKLEIQ 1930
Score = 63.3 bits (147), Expect = 8e-09
Identities = 83/356 (23%), Positives = 134/356 (37%), Gaps = 48/356 (13%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
VL P+ + ++G+ + K++GRP P+ WFH+ + I + ++ G + I
Sbjct: 1460 VLKPV-SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV 1518
Query: 1344 EAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIV 1403
A P +G + A N+ G+ S IL +EA E+ + P V
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH-------------------QVKPMFV 1559
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTSILTMP 1462
+ L V EG + ++ +A G P P + WL+ ++ +I E G + L +
Sbjct: 1560 EKLKN-VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1618
Query: 1463 EVYQDDTGEIVFEAYNHLGVTATIAALSVE-----------SIVGTQEYRKPEWVT---- 1507
D+ A N G T ++VE I+ YR E
Sbjct: 1619 STVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELE 1678
Query: 1508 --HM-------EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS--GNPTPEILW 1556
H+ EE K Q P F K++ R+ FE + G+PT + W
Sbjct: 1679 PLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEW 1738
Query: 1557 YKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D K + R + N+ + A G TC+A + G T A L V
Sbjct: 1739 LHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 62.9 bits (146), Expect = 1e-08
Identities = 59/214 (27%), Positives = 94/214 (43%), Gaps = 20/214 (9%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI- 1458
P++++ L V T GK R A G P+P++ W ++ E L ST ++ + L DG
Sbjct: 3239 PQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKE--EQLLSTGFKCKFLHDGQEYT 3295
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E + +D EA N GV T A+LSVE PE V+ +E+
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV---------PEVVSPDQEMPVY--- 3343
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P + + E + F+ SG ++ WY +K I+ F + E+
Sbjct: 3344 ---PPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 3399
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A + EGTYT A + +G + A L +
Sbjct: 3400 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 59.7 bits (138), Expect = 1e-07
Identities = 51/226 (22%), Positives = 88/226 (38%), Gaps = 18/226 (7%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + P+ + + + C ++G P P++ W+ IE + ++ G +
Sbjct: 5380 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 5439
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEY-----------VPSVSEEDVLSDE 1390
I+ + Y+C A N G+ L + E + S+ EE VL
Sbjct: 5440 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 5499
Query: 1391 KTSDVEEF-----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST 1445
T EF PR +K + G + G P+P V W + G +L+Q
Sbjct: 5500 YTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVRGSPRPTVYWYKDG-KLVQGR 5557
Query: 1446 EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ +EE G L + + + D GE A N G+ + AAL++
Sbjct: 5558 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 56.8 bits (131), Expect = 7e-07
Identities = 27/90 (30%), Positives = 46/90 (51%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F++EI + V+E + F + G P P + WY ++ I ++ FII + EN + T+
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
EG+ TC + G T + L+V
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
Score = 55.6 bits (128), Expect = 2e-06
Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
P+ Y+ + G E +GV+ T + E + + VT + A ++ +
Sbjct: 887 PDTYKSEAG---VEVKKEVGVSITGTTVREERFEVL--HGREAKVTETARVPAPVEIPVT 941
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT V + V E E VT E SG P+P + WY+++ I + F I +
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++A + G +TC AV++ G T L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 54.4 bits (125), Expect = 4e-06
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 18/257 (7%)
Query: 1370 LNIEAYEYV-PSVSEEDVLSDEKTSDVE--EFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
L++ + +V P++ + E D+E E PR + + + + IG
Sbjct: 5347 LDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAV-FKCSVIG 5405
Query: 1427 IPKPQVRWLRQGTELL-QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTAT 1485
IP P+V+W ++ + + +Y I E + G+ L + V D+ A N +G
Sbjct: 5406 IPTPEVKWYKEYMCIEPDNIKYVISE-EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAIC 5464
Query: 1486 IAALSV---ESIVGTQEYRKPEWVTHMEELQAALKATQSV---------PTFVKEIIPER 1533
L++ E + K + MEEL T S P F+K I
Sbjct: 5465 RGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCY 5524
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
F+ + G+P P + WYKD K+++ + E+ I K EG Y
Sbjct: 5525 APIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEY 5584
Query: 1594 TCKAVSDIGLAVTKAKL 1610
C A + G+A + A L
Sbjct: 5585 RCVATNKSGMAESFAAL 5601
Score = 54.0 bits (124), Expect = 5e-06
Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Query: 1393 SDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEEL 1452
SD+ P++++ +P EG I LE G P+P V W + G L Q+ ++Q EE+
Sbjct: 4151 SDITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEV 4210
Query: 1453 DDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ L + +V D+G+ A N+ G +++ L+VE +
Sbjct: 4211 NCSHQ-LYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPV 4251
Score = 54.0 bits (124), Expect = 5e-06
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKEN 1576
K + P+F++ + +V+E + F G P P + WY++ ++ DER +E N
Sbjct: 5177 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 5236
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I K G Y C AV+ IG A + A + +
Sbjct: 5237 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272
Score = 53.6 bits (123), Expect = 7e-06
Identities = 75/338 (22%), Positives = 135/338 (39%), Gaps = 20/338 (5%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
+VL P E V++GE C++ G P PK++W+ N +LI ++ + + G+ + I
Sbjct: 1843 IVLYP-EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLDI 1899
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR- 1401
+ G K TA N G + L I+ E SV + E + P
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRR---APEPRPEFHVHEPGK 1956
Query: 1402 ---IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE-LDDGTS 1457
V+ + V TTE K + +A I +V + EL + + EE + +
Sbjct: 1957 LQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVP--EESEELRSKFKRRTEEGYYEAIT 2014
Query: 1458 ILTMPEVYQDDTGEIVFEAYNH--LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ + +D++ E + L T + +++ + P + EL +
Sbjct: 2015 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2074
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN-KVIRTDERFIIENK 1574
++A P + I + V + F G P PE WYK+ K+ R+D + +
Sbjct: 2075 MEA----PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+N I+ T + + KA++ G + A L V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2168
Score = 52.8 bits (121), Expect = 1e-05
Identities = 66/332 (19%), Positives = 127/332 (38%), Gaps = 28/332 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L +E+ V +G+ + C G P P + W++N+ I ++ I ++ +
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLEN-YSILT 4002
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
+ + G C NQ+G T +L ++A + + + + + + EE A
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEELALV 4062
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ-STEYQIEELDDGTSILT 1460
+A + ++ L P P TELL E Q+ T+
Sbjct: 4063 FDQAKGAHPSMSQEGQTNLHLLKTNPPVPP----SGDTELLSFPVEIQV------TAATP 4112
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+PE QD + VF+ A+ + + + ++R +V + K Q
Sbjct: 4113 IPE--QDKESKEVFQTEE-----LEPKAMPQDQVTQSPKHR---FVFLSDITNEPPKMLQ 4162
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
+P R E + + E + SG P P + W+++ +++ +++F E
Sbjct: 4163 EMPKHA------RCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQL 4216
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
IK G Y C A ++ G + + L V
Sbjct: 4217 YIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 50.8 bits (116), Expect = 5e-05
Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP + +++ TV G +++G+P P+ +W+ N IE + I + +CE
Sbjct: 2076 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE-EDVLSDEK 1391
+ I++ E + A N G+ S+ L ++A + + E +DV++ EK
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEK 2188
Score = 50.4 bits (115), Expect = 6e-05
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%)
Query: 1510 EELQAALKATQSVPT-FVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER 1568
E++ + +++V + F I R+ E VTF SG P P+I WYKD K I+ ER
Sbjct: 1277 EKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1336
Query: 1569 FIIE-NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ ++ R + I + EG YT A + G A+ KL V
Sbjct: 1337 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV 1381
Score = 49.6 bits (113), Expect = 1e-04
Identities = 41/153 (26%), Positives = 66/153 (43%), Gaps = 8/153 (5%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLENTTVMDGERISLNCKILGR 1308
G T A+N AG S S VE ++ P+ + L+N + +G R+ + + G
Sbjct: 1526 GEWTVVAQNRAGRSSISVILTVE---AVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGN 1582
Query: 1309 PWPKIDWFHNEKLIETAR--DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P P I W N +I + I I K G + I + + Y TA N+ G+ +T
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTK-GEAALKIDSTVSQDSAWYTATAINKAGRDTT 1641
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
C +N+E E+ E ++ T +E A
Sbjct: 1642 RCKVNVEV-EFAEPEPERKLIIPRGTYRAKEIA 1673
Score = 48.4 bits (110), Expect = 2e-04
Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 17/206 (8%)
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
IG P V WL G L + ++ + G L Y D+G I A N G
Sbjct: 1729 IGDPTMVVEWLHDGKPLEAANRLRMIN-EFGYCSLDYGVAYSRDSGIITCRATNKYGTDH 1787
Query: 1485 TIAALSVESIVG-TQEYRKPEW---VTHMEELQ--AALKATQSVPTFVKE-------IIP 1531
T A L V+ +E + PE + +EEL+ A A V T KE + P
Sbjct: 1788 TSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYP 1847
Query: 1532 E--RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
E RV E E F +G P P++ WY + ++IR +RF + + + D
Sbjct: 1848 EPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYD- 1906
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQVFQR 1615
G A + G+ K KL++ QR
Sbjct: 1907 TGEVKVTAENPEGVIEHKVKLEIQQR 1932
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
Query: 1277 IDGDAPLVLAPL-ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKS 1335
I + P +L + ++ +G+ I L C I G P P + WF N L++ +
Sbjct: 4153 ITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNC 4212
Query: 1336 GLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDV 1386
+++IK+ + +G YKC A N G + L +E Y + E++
Sbjct: 4213 S-HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQFENI 4262
Score = 46.8 bits (106), Expect = 8e-04
Identities = 38/151 (25%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 1263 VSTSGSSIVEEQTCI-DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
V + +S+ EEQ + AP + +++G + C++ G P P + W +
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121
Query: 1322 IETARDITISRQK-SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA-YEYVP 1379
+ T +S K +G C++ I F + AG Y N+ G+ S L EA YE +
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLM 1181
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
+E + + T+ V+E P++ + P V
Sbjct: 1182 KSQQEMLYQTQVTAFVQE--PKVGETAPGFV 1210
Score = 44.8 bits (101), Expect = 0.003
Identities = 50/215 (23%), Positives = 92/215 (42%), Gaps = 30/215 (13%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
AP+I + + + T +G + +G P P+ W + G ++ +S +D
Sbjct: 2077 APKIFERIQSQ-TVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + +V +D+ I+ +A N G T++ A L V++ + +T +ELQ +
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA---------KQLITFTQELQDVV-- 2184
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
KE ++ + TFE + P ++ WYKD + +++ + +
Sbjct: 2185 -------AKE-------KDTMATFEC-ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVH 2229
Query: 1579 TCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+I T D E Y+C V D + T AKL V
Sbjct: 2230 FLSILTIDTSDAE-DYSCVLVEDENVKTT-AKLIV 2262
Score = 44.0 bits (99), Expect = 0.005
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 4/97 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK----ENRT 1578
P+F +++ + V E E V F PTPE+ W+ +N+ I T R II+ + + +
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ IK+ G+Y A++ G A + A L V Q+
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600
Score = 40.3 bits (90), Expect = 0.066
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKS---GLCEIHIKEAFPEM 1349
V++GE + C+++ P P++ WFHN + I T I + + IK
Sbjct: 3515 VLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRD 3574
Query: 1350 AGIYKCTASNQFGKC-STECILNIE 1373
+G Y+ A N G ST +L I+
Sbjct: 3575 SGSYRLLAINSEGSAESTASLLVIQ 3599
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A L +V FVKE+ V E E I S E WY ++ ++++ ++ I +
Sbjct: 2258 AKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENI-EGKWYHNDVELKSNGKYTITS 2316
Query: 1574 KENRTTCTIKKATKDLEGTYT 1594
+ R T+K TK+ +G Y+
Sbjct: 2317 RRGRQNLTVKDVTKEDQGEYS 2337
>AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein
protein.
Length = 1320
Score = 96.7 bits (230), Expect = 7e-19
Identities = 92/346 (26%), Positives = 146/346 (42%), Gaps = 38/346 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCE 1339
AP+ L++ V +G ++ CKI+G P PK+ WF + K I + + R+ G C
Sbjct: 944 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE-- 1397
+HI+ + G Y A+N G+ S L +++ ++ S S V+E
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQ-SHRGRSRVQERD 1062
Query: 1398 --------FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
F P ++A P + EG+L RL+ K G+P P++ WL G +L +++
Sbjct: 1063 KEPLQERFFRPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKM 1121
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
+ G L + + Q D G A N G + S+E V +E +K + +
Sbjct: 1122 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN----SFSLELSVVAKEVKKAPVI--L 1175
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR-TDER 1568
E+LQ VP E V E G P P W KDN+ I T ER
Sbjct: 1176 EKLQNC-----GVP------------EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRER 1218
Query: 1569 FIIENKENRTTC-TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ C I+ A K G YT A ++ G+ A+L ++
Sbjct: 1219 ISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 1264
Score = 68.5 bits (160), Expect = 2e-10
Identities = 33/103 (32%), Positives = 56/103 (54%), Gaps = 7/103 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK------ 1334
AP+ L+N + +G+ + C++ G P PK++W+ LIE + D IS++K
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAE 493
Query: 1335 -SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+C + I E F E +G + CTASN++G S+ L++ E
Sbjct: 494 PEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNE 536
Score = 64.9 bits (151), Expect = 3e-09
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
Query: 1256 AENFAGSVSTSGSS---IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
A AG +T GSS + E+ G P L + V +G R+ L+C ++G P P+
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQ 299
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ W+ K +E + DI I Q L + I EAF E G Y C ASN +G ST
Sbjct: 300 VRWYCEGKELENSPDIHIV-QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDST------ 352
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPT 1408
A Y+ VS D D ++ P V + PT
Sbjct: 353 SAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPT 389
Score = 58.4 bits (135), Expect = 2e-07
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
EG ++L+ +GIP PQVRW +G EL S + I + + S LT+ E +++DTG
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHS-LTIAEAFEEDTGRYS 340
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ-SVPTFVKEIIPE 1532
A N G +T A + +E + + P + EE+ K + S P +IP
Sbjct: 341 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP----NKEEMNRIQKPNEVSSPPTTSAVIPP 396
Query: 1533 RVHEEE 1538
V + +
Sbjct: 397 AVPQAQ 402
Score = 58.0 bits (134), Expect = 3e-07
Identities = 57/236 (24%), Positives = 92/236 (38%), Gaps = 12/236 (5%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E P +D + ++ + AP K L TEG + K +GIP P+V W
Sbjct: 921 ERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVPKVYWF 979
Query: 1436 RQGTELLQSTEY-QIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ G ++ + E+ ++ DGT L + DD G A N G + L V+S+
Sbjct: 980 KDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 1039
Query: 1495 V-------GTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
Q +R V E + L+ P F++ HE + + S
Sbjct: 1040 PIRSRLTSAGQSHRGRSRV--QERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVS 1097
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRT-TCTIKKATKDLEGTYTCKAVSDIG 1602
G P PE+ W + + + D + +E + I T+ GTY C A + G
Sbjct: 1098 GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTG 1153
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 5/127 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G C A N G S S S+V ++ AP++L L+N V +G + L C+++G
Sbjct: 1142 GTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNCGVPEGHPVRLECRVIGM 1198
Query: 1309 PWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P W + + I R+ I++ + +G + I+ A AG Y +A N+ G S
Sbjct: 1199 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258
Query: 1368 CILNIEA 1374
L+I A
Sbjct: 1259 ARLDIYA 1265
Score = 46.8 bits (106), Expect = 8e-04
Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE-----LD 1453
AP K L + + +EG+L+ E + G P P+V W R+GT + S +++I + +
Sbjct: 434 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMA 492
Query: 1454 DGTSILTM--PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ I T+ EV+ + +G A N G ++IA L V
Sbjct: 493 EPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHV 532
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 8/100 (8%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT-- 1578
+ P F K + E ++V FE G P+P++ WY++ +I F I K+ R+
Sbjct: 433 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMA 492
Query: 1579 ----TCTIKKATKDLEGT--YTCKAVSDIGLAVTKAKLQV 1612
CT+ A EG+ +TC A + G + A+L V
Sbjct: 493 EPEEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHV 532
Score = 43.2 bits (97), Expect = 0.009
Identities = 24/90 (26%), Positives = 41/90 (45%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F +++ V E V + I G P P++ WY + K + I N + TI
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+A ++ G Y+C A + G T A++ +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
>AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1320
Score = 96.7 bits (230), Expect = 7e-19
Identities = 92/346 (26%), Positives = 146/346 (42%), Gaps = 38/346 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCE 1339
AP+ L++ V +G ++ CKI+G P PK+ WF + K I + + R+ G C
Sbjct: 944 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE-- 1397
+HI+ + G Y A+N G+ S L +++ ++ S S V+E
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQ-SHRGRSRVQERD 1062
Query: 1398 --------FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
F P ++A P + EG+L RL+ K G+P P++ WL G +L +++
Sbjct: 1063 KEPLQERFFRPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKM 1121
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
+ G L + + Q D G A N G + S+E V +E +K + +
Sbjct: 1122 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN----SFSLELSVVAKEVKKAPVI--L 1175
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR-TDER 1568
E+LQ VP E V E G P P W KDN+ I T ER
Sbjct: 1176 EKLQNC-----GVP------------EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRER 1218
Query: 1569 FIIENKENRTTC-TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ C I+ A K G YT A ++ G+ A+L ++
Sbjct: 1219 ISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 1264
Score = 66.1 bits (154), Expect = 1e-09
Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK------ 1334
AP+ L+N + +G+ + C++ G P PK++W+ LIE + D I ++K
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 1335 -SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+C + I E F E +G + CTASN++G S+ L++ E
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNE 536
Score = 64.9 bits (151), Expect = 3e-09
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
Query: 1256 AENFAGSVSTSGSS---IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
A AG +T GSS + E+ G P L + V +G R+ L+C ++G P P+
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQ 299
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ W+ K +E + DI I Q L + I EAF E G Y C ASN +G ST
Sbjct: 300 VRWYCEGKELENSPDIHIV-QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDST------ 352
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPT 1408
A Y+ VS D D ++ P V + PT
Sbjct: 353 SAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPT 389
Score = 58.4 bits (135), Expect = 2e-07
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
EG ++L+ +GIP PQVRW +G EL S + I + + S LT+ E +++DTG
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHS-LTIAEAFEEDTGRYS 340
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ-SVPTFVKEIIPE 1532
A N G +T A + +E + + P + EE+ K + S P +IP
Sbjct: 341 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP----NKEEMNRIQKPNEVSSPPTTSAVIPP 396
Query: 1533 RVHEEE 1538
V + +
Sbjct: 397 AVPQAQ 402
Score = 58.0 bits (134), Expect = 3e-07
Identities = 57/236 (24%), Positives = 92/236 (38%), Gaps = 12/236 (5%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E P +D + ++ + AP K L TEG + K +GIP P+V W
Sbjct: 921 ERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVPKVYWF 979
Query: 1436 RQGTELLQSTEY-QIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ G ++ + E+ ++ DGT L + DD G A N G + L V+S+
Sbjct: 980 KDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 1039
Query: 1495 V-------GTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
Q +R V E + L+ P F++ HE + + S
Sbjct: 1040 PIRSRLTSAGQSHRGRSRV--QERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVS 1097
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRT-TCTIKKATKDLEGTYTCKAVSDIG 1602
G P PE+ W + + + D + +E + I T+ GTY C A + G
Sbjct: 1098 GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTG 1153
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 5/127 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G C A N G S S S+V ++ AP++L L+N V +G + L C+++G
Sbjct: 1142 GTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNCGVPEGHPVRLECRVIGM 1198
Query: 1309 PWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P W + + I R+ I++ + +G + I+ A AG Y +A N+ G S
Sbjct: 1199 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258
Query: 1368 CILNIEA 1374
L+I A
Sbjct: 1259 ARLDIYA 1265
Score = 48.8 bits (111), Expect = 2e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI-----EELD 1453
AP K L + + +EG+L+ E + G P P+V W R+GT + S +++I +
Sbjct: 434 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492
Query: 1454 DGTSILTM--PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ I T+ EV+ +D+G A N G ++IA L V
Sbjct: 493 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 43.2 bits (97), Expect = 0.009
Identities = 24/90 (26%), Positives = 41/90 (45%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F +++ V E V + I G P P++ WY + K + I N + TI
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+A ++ G Y+C A + G T A++ +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT-- 1578
+ P F K + E ++V FE G P+P++ WY++ +I F I K+ R+
Sbjct: 433 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492
Query: 1579 ------TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
T I + + G +TC A + G + A+L V
Sbjct: 493 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
>AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1045
Score = 96.7 bits (230), Expect = 7e-19
Identities = 92/346 (26%), Positives = 146/346 (42%), Gaps = 38/346 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCE 1339
AP+ L++ V +G ++ CKI+G P PK+ WF + K I + + R+ G C
Sbjct: 669 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 728
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE-- 1397
+HI+ + G Y A+N G+ S L +++ ++ S S V+E
Sbjct: 729 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQ-SHRGRSRVQERD 787
Query: 1398 --------FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
F P ++A P + EG+L RL+ K G+P P++ WL G +L +++
Sbjct: 788 KEPLQERFFRPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKM 846
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
+ G L + + Q D G A N G + S+E V +E +K + +
Sbjct: 847 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN----SFSLELSVVAKEVKKAPVI--L 900
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR-TDER 1568
E+LQ VP E V E G P P W KDN+ I T ER
Sbjct: 901 EKLQNC-----GVP------------EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRER 943
Query: 1569 FIIENKENRTTC-TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ C I+ A K G YT A ++ G+ A+L ++
Sbjct: 944 ISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 989
Score = 66.1 bits (154), Expect = 1e-09
Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK------ 1334
AP+ L+N + +G+ + C++ G P PK++W+ LIE + D I ++K
Sbjct: 159 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 1335 -SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+C + I E F E +G + CTASN++G S+ L++ E
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNE 261
Score = 58.0 bits (134), Expect = 3e-07
Identities = 57/236 (24%), Positives = 92/236 (38%), Gaps = 12/236 (5%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E P +D + ++ + AP K L TEG + K +GIP P+V W
Sbjct: 646 ERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVPKVYWF 704
Query: 1436 RQGTELLQSTEY-QIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ G ++ + E+ ++ DGT L + DD G A N G + L V+S+
Sbjct: 705 KDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 764
Query: 1495 V-------GTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
Q +R V E + L+ P F++ HE + + S
Sbjct: 765 PIRSRLTSAGQSHRGRSRV--QERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVS 822
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRT-TCTIKKATKDLEGTYTCKAVSDIG 1602
G P PE+ W + + + D + +E + I T+ GTY C A + G
Sbjct: 823 GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTG 878
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 5/127 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G C A N G S S S+V ++ AP++L L+N V +G + L C+++G
Sbjct: 867 GTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNCGVPEGHPVRLECRVIGM 923
Query: 1309 PWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P W + + I R+ I++ + +G + I+ A AG Y +A N+ G S
Sbjct: 924 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 983
Query: 1368 CILNIEA 1374
L+I A
Sbjct: 984 ARLDIYA 990
Score = 48.8 bits (111), Expect = 2e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI-----EELD 1453
AP K L + + +EG+L+ E + G P P+V W R+GT + S +++I +
Sbjct: 159 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217
Query: 1454 DGTSILTM--PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ I T+ EV+ +D+G A N G ++IA L V
Sbjct: 218 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT-- 1578
+ P F K + E ++V FE G P+P++ WY++ +I F I K+ R+
Sbjct: 158 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217
Query: 1579 ------TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
T I + + G +TC A + G + A+L V
Sbjct: 218 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/95 (33%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 1315 WFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
W+ K +E + DI I Q L + I EAF E G Y C ASN +G ST A
Sbjct: 27 WYCEGKELENSPDIHIV-QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDST------SA 79
Query: 1375 YEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPT 1408
Y+ VS D D ++ P V + PT
Sbjct: 80 EIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPT 114
>AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.
Length = 1320
Score = 96.7 bits (230), Expect = 7e-19
Identities = 92/346 (26%), Positives = 146/346 (42%), Gaps = 38/346 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCE 1339
AP+ L++ V +G ++ CKI+G P PK+ WF + K I + + R+ G C
Sbjct: 944 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 1003
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE-- 1397
+HI+ + G Y A+N G+ S L +++ ++ S S V+E
Sbjct: 1004 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQ-SHRGRSRVQERD 1062
Query: 1398 --------FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
F P ++A P + EG+L RL+ K G+P P++ WL G +L +++
Sbjct: 1063 KEPLQERFFRPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKM 1121
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
+ G L + + Q D G A N G + S+E V +E +K + +
Sbjct: 1122 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN----SFSLELSVVAKEVKKAPVI--L 1175
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR-TDER 1568
E+LQ VP E V E G P P W KDN+ I T ER
Sbjct: 1176 EKLQNC-----GVP------------EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRER 1218
Query: 1569 FIIENKENRTTC-TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ C I+ A K G YT A ++ G+ A+L ++
Sbjct: 1219 ISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 1264
Score = 66.1 bits (154), Expect = 1e-09
Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK------ 1334
AP+ L+N + +G+ + C++ G P PK++W+ LIE + D I ++K
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 1335 -SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+C + I E F E +G + CTASN++G S+ L++ E
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNE 536
Score = 64.9 bits (151), Expect = 3e-09
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
Query: 1256 AENFAGSVSTSGSS---IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
A AG +T GSS + E+ G P L + V +G R+ L+C ++G P P+
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQ 299
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ W+ K +E + DI I Q L + I EAF E G Y C ASN +G ST
Sbjct: 300 VRWYCEGKELENSPDIHIV-QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDST------ 352
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPT 1408
A Y+ VS D D ++ P V + PT
Sbjct: 353 SAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPT 389
Score = 58.4 bits (135), Expect = 2e-07
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
EG ++L+ +GIP PQVRW +G EL S + I + + S LT+ E +++DTG
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHS-LTIAEAFEEDTGRYS 340
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ-SVPTFVKEIIPE 1532
A N G +T A + +E + + P + EE+ K + S P +IP
Sbjct: 341 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP----NKEEMNRIQKPNEVSSPPTTSAVIPP 396
Query: 1533 RVHEEE 1538
V + +
Sbjct: 397 AVPQAQ 402
Score = 58.0 bits (134), Expect = 3e-07
Identities = 57/236 (24%), Positives = 92/236 (38%), Gaps = 12/236 (5%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E P +D + ++ + AP K L TEG + K +GIP P+V W
Sbjct: 921 ERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVPKVYWF 979
Query: 1436 RQGTELLQSTEY-QIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ G ++ + E+ ++ DGT L + DD G A N G + L V+S+
Sbjct: 980 KDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 1039
Query: 1495 V-------GTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
Q +R V E + L+ P F++ HE + + S
Sbjct: 1040 PIRSRLTSAGQSHRGRSRV--QERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVS 1097
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRT-TCTIKKATKDLEGTYTCKAVSDIG 1602
G P PE+ W + + + D + +E + I T+ GTY C A + G
Sbjct: 1098 GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTG 1153
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 5/127 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G C A N G S S S+V ++ AP++L L+N V +G + L C+++G
Sbjct: 1142 GTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNCGVPEGHPVRLECRVIGM 1198
Query: 1309 PWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P W + + I R+ I++ + +G + I+ A AG Y +A N+ G S
Sbjct: 1199 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258
Query: 1368 CILNIEA 1374
L+I A
Sbjct: 1259 ARLDIYA 1265
Score = 48.8 bits (111), Expect = 2e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI-----EELD 1453
AP K L + + +EG+L+ E + G P P+V W R+GT + S +++I +
Sbjct: 434 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492
Query: 1454 DGTSILTM--PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ I T+ EV+ +D+G A N G ++IA L V
Sbjct: 493 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
Score = 43.2 bits (97), Expect = 0.009
Identities = 24/90 (26%), Positives = 41/90 (45%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F +++ V E V + I G P P++ WY + K + I N + TI
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+A ++ G Y+C A + G T A++ +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT-- 1578
+ P F K + E ++V FE G P+P++ WY++ +I F I K+ R+
Sbjct: 433 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492
Query: 1579 ------TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
T I + + G +TC A + G + A+L V
Sbjct: 493 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532
>AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein
protein.
Length = 1391
Score = 96.3 bits (229), Expect = 9e-19
Identities = 92/346 (26%), Positives = 146/346 (42%), Gaps = 38/346 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCE 1339
AP+ L++ V +G ++ CKI+G P PK+ WF + K I + + R+ G C
Sbjct: 1015 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCS 1074
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE-- 1397
+HI+ + G Y A+N G+ S L +++ ++ S S V+E
Sbjct: 1075 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQ-SHRGRSRVQERD 1133
Query: 1398 --------FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
F P ++A P + EG+L RL+ K G+P P++ WL G +L +++
Sbjct: 1134 KEPLQERFFRPHFLQA-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKM 1192
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
+ G L + + Q D G A N G + S+E V +E +K + +
Sbjct: 1193 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN----SFSLELSVVAKEVKKAPVI--L 1246
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR-TDER 1568
E+LQ VP E V E G P P W KDN+ I T ER
Sbjct: 1247 EKLQNC-----GVP------------EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRER 1289
Query: 1569 FIIENKENRTTC-TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ C I+ A K G YT A ++ G+ A+L ++
Sbjct: 1290 ISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 1335
Score = 66.1 bits (154), Expect = 1e-09
Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK------ 1334
AP+ L+N + +G+ + C++ G P PK++W+ LIE + D I ++K
Sbjct: 505 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 564
Query: 1335 -SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+C + I E F E +G + CTASN++G S+ L++ E
Sbjct: 565 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNE 607
Score = 64.9 bits (151), Expect = 3e-09
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
Query: 1256 AENFAGSVSTSGSS---IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
A AG +T GSS + E+ G P L + V +G R+ L+C ++G P P+
Sbjct: 313 ASEAAGGDTTPGSSPSSLYYEEPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQ 370
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ W+ K +E + DI I Q L + I EAF E G Y C ASN +G ST
Sbjct: 371 VRWYCEGKELENSPDIHIV-QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDST------ 423
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPT 1408
A Y+ VS D D ++ P V + PT
Sbjct: 424 SAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPT 460
Score = 58.4 bits (135), Expect = 2e-07
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
EG ++L+ +GIP PQVRW +G EL S + I + + S LT+ E +++DTG
Sbjct: 353 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHS-LTIAEAFEEDTGRYS 411
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ-SVPTFVKEIIPE 1532
A N G +T A + +E + + P + EE+ K + S P +IP
Sbjct: 412 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP----NKEEMNRIQKPNEVSSPPTTSAVIPP 467
Query: 1533 RVHEEE 1538
V + +
Sbjct: 468 AVPQAQ 473
Score = 56.0 bits (129), Expect = 1e-06
Identities = 57/236 (24%), Positives = 91/236 (38%), Gaps = 12/236 (5%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E P +D + ++ + AP K L TEG + K +GIP P+V W
Sbjct: 992 ERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVPKVYWF 1050
Query: 1436 RQGTELLQSTEY-QIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ G ++ + E ++ DGT L + DD G A N G + L V+S+
Sbjct: 1051 KDGKQISKRNERCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 1110
Query: 1495 V-------GTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
Q +R V E + L+ P F++ HE + + S
Sbjct: 1111 PIRSRLTSAGQSHRGRSRV--QERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVS 1168
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRT-TCTIKKATKDLEGTYTCKAVSDIG 1602
G P PE+ W + + + D + +E + I T+ GTY C A + G
Sbjct: 1169 GLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTG 1224
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 5/127 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G C A N G S S S+V ++ AP++L L+N V +G + L C+++G
Sbjct: 1213 GTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNCGVPEGHPVRLECRVIGM 1269
Query: 1309 PWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P W + + I R+ I++ + +G + I+ A AG Y +A N+ G S
Sbjct: 1270 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1329
Query: 1368 CILNIEA 1374
L+I A
Sbjct: 1330 ARLDIYA 1336
Score = 48.8 bits (111), Expect = 2e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI-----EELD 1453
AP K L + + +EG+L+ E + G P P+V W R+GT + S +++I +
Sbjct: 505 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 563
Query: 1454 DGTSILTM--PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ I T+ EV+ +D+G A N G ++IA L V
Sbjct: 564 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 603
Score = 43.2 bits (97), Expect = 0.009
Identities = 24/90 (26%), Positives = 41/90 (45%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F +++ V E V + I G P P++ WY + K + I N + TI
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 399
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+A ++ G Y+C A + G T A++ +
Sbjct: 400 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT-- 1578
+ P F K + E ++V FE G P+P++ WY++ +I F I K+ R+
Sbjct: 504 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 563
Query: 1579 ------TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
T I + + G +TC A + G + A+L V
Sbjct: 564 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 603
>AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein
protein.
Length = 1045
Score = 95.1 bits (226), Expect = 2e-18
Identities = 91/346 (26%), Positives = 145/346 (41%), Gaps = 38/346 (10%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCE 1339
AP+ L++ V +G ++ CKI+G P PK+ WF + K I + + R+ G C
Sbjct: 669 APIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS 728
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE-- 1397
+HI+ + G Y A+N G+ S L +++ ++ S S V+E
Sbjct: 729 LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQ-SHRGRSRVQERD 787
Query: 1398 --------FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
F P ++ P + EG+L RL+ K G+P P++ WL G +L +++
Sbjct: 788 KEPLQERFFRPHFLQT-PGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKM 846
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
+ G L + + Q D G A N G + S+E V +E +K + +
Sbjct: 847 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN----SFSLELSVVAKEVKKAPVI--L 900
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIR-TDER 1568
E+LQ VP E V E G P P W KDN+ I T ER
Sbjct: 901 EKLQNC-----GVP------------EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRER 943
Query: 1569 FIIENKENRTTC-TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ C I+ A K G YT A ++ G+ A+L ++
Sbjct: 944 ISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 989
Score = 66.1 bits (154), Expect = 1e-09
Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK------ 1334
AP+ L+N + +G+ + C++ G P PK++W+ LIE + D I ++K
Sbjct: 159 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 1335 -SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+C + I E F E +G + CTASN++G S+ L++ E
Sbjct: 219 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNE 261
Score = 58.0 bits (134), Expect = 3e-07
Identities = 57/236 (24%), Positives = 92/236 (38%), Gaps = 12/236 (5%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E P +D + ++ + AP K L TEG + K +GIP P+V W
Sbjct: 646 ERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHF-RVTEGSPVTFTCKIVGIPVPKVYWF 704
Query: 1436 RQGTELLQSTEY-QIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ G ++ + E+ ++ DGT L + DD G A N G + L V+S+
Sbjct: 705 KDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 764
Query: 1495 V-------GTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
Q +R V E + L+ P F++ HE + + S
Sbjct: 765 PIRSRLTSAGQSHRGRSRV--QERDKEPLQERFFRPHFLQTPGDMVAHEGRLCRLDCKVS 822
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRT-TCTIKKATKDLEGTYTCKAVSDIG 1602
G P PE+ W + + + D + +E + I T+ GTY C A + G
Sbjct: 823 GLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTG 878
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 5/127 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G C A N G S S S+V ++ AP++L L+N V +G + L C+++G
Sbjct: 867 GTYKCIATNKTGQNSFSLELSVVAKEV---KKAPVILEKLQNCGVPEGHPVRLECRVIGM 923
Query: 1309 PWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
P P W + + I R+ I++ + +G + I+ A AG Y +A N+ G S
Sbjct: 924 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 983
Query: 1368 CILNIEA 1374
L+I A
Sbjct: 984 ARLDIYA 990
Score = 48.8 bits (111), Expect = 2e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI-----EELD 1453
AP K L + + +EG+L+ E + G P P+V W R+GT + S +++I +
Sbjct: 159 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217
Query: 1454 DGTSILTM--PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ I T+ EV+ +D+G A N G ++IA L V
Sbjct: 218 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 8/100 (8%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT-- 1578
+ P F K + E ++V FE G P+P++ WY++ +I F I K+ R+
Sbjct: 158 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 217
Query: 1579 ------TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
T I + + G +TC A + G + A+L V
Sbjct: 218 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 257
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/95 (33%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 1315 WFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
W+ K +E + DI I Q L + I EAF E G Y C ASN +G ST A
Sbjct: 27 WYCEGKELENSPDIHIV-QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDST------SA 79
Query: 1375 YEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPT 1408
Y+ VS D D ++ P V + PT
Sbjct: 80 EIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPT 114
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 92.3 bits (219), Expect = 2e-17
Identities = 80/334 (23%), Positives = 142/334 (42%), Gaps = 35/334 (10%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P ++ PL++T +G+ C++ G K+ W+ +K I+ +R ++ Q ++
Sbjct: 10 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLE 67
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
I EA+PE G Y A+N G+ S+ L++EA E S+ E + E+ ++E A
Sbjct: 68 IAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPE---SILHERI---EQEIEMEMKAAP 121
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM 1461
++K + G L + + P + +W + G E+ +S + I S L +
Sbjct: 122 VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS-SKYISSLEI 180
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
D GE +A N G + A L+V T+ Y P + L +S
Sbjct: 181 LRTQVVDCGEYTCKASNEYGSVSCTATLTV-----TEAY-PPTF----------LSRPKS 224
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
+ TFV + F +G P E +W KD + + I + EN+
Sbjct: 225 LTTFV----------GKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILE 274
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ T G Y+CKA + G + +A+L + +
Sbjct: 275 LSNLTIQDRGVYSCKASNKFGADICQAELIIIDK 308
Score = 86.6 bits (205), Expect = 8e-16
Identities = 93/385 (24%), Positives = 157/385 (40%), Gaps = 60/385 (15%)
Query: 1218 IIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
++ +D L + + L +L+ ++S G +C A N G+ S+S E
Sbjct: 2878 VLLRDHENLQTSFVDNVATLKILQTDLSHS--GQYSCSASNPLGTASSSARLTAREPK-- 2933
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+P + V+ GE C + G +I W + K I + TI+
Sbjct: 2934 --KSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCV-GNT 2990
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE 1397
+ I + +G Y C A+N GK D+ S + + V+E
Sbjct: 2991 PHLRILKVGKGDSGQYTCQATNDVGK---------------------DMCSAQLS--VKE 3027
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
P+ VK L +G+ I+LE K G P+ +V W R +EL +S +Y + + + +
Sbjct: 3028 -PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFI-NSVA 3085
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
+LT+ E +D+G+ + EA+N +G + AL+V++ P T ALK
Sbjct: 3086 LLTINEASAEDSGDYICEAHNGVGDASCSTALTVKA---------PPVFTQKPSPVGALK 3136
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
+ V + SG P E++W KD K +R ++F I +K
Sbjct: 3137 GSD-------------------VILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFD 3177
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIG 1602
T I G Y CKA +++G
Sbjct: 3178 TNLHILNLEASDVGEYHCKATNEVG 3202
Score = 78.6 bits (185), Expect = 2e-13
Identities = 88/373 (23%), Positives = 149/373 (39%), Gaps = 41/373 (10%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
+ K G TC A N G S + ++E+ + +E T +G L
Sbjct: 4880 VDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEET---EGNSFKLEG 4936
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G + W+ N I+ + I+ + + L + +++A AG+Y C SN G
Sbjct: 4937 RVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLV-LQVRKAGMNDAGLYTCKVSNDAG- 4994
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAK 1423
S C +I V+ + K P + T VT +EG+ ++L
Sbjct: 4995 -SALCTSSI-------------VIKEPKK-------PPVFDQHLTPVTVSEGEYVQLSCH 5033
Query: 1424 AIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVT 1483
G +++WL+ G E+ S GT++L + +V + D+G+ V +A N G
Sbjct: 5034 VQGSEPIRIQWLKAGREIKPSDRCSFS-FASGTAVLELRDVAKADSGDYVCKASNVAGSD 5092
Query: 1484 ATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFE 1543
T + ++++ KP ++ A FV E RV E+ TF
Sbjct: 5093 TTKSKVTIKD--------KPAVAPATKKA-----AVDGRLFFVSEPQSIRVVEKTTATFI 5139
Query: 1544 AIYSGNPTPEILWYKDN-KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
A G+P P + W K + + R I K + I+ TK G Y C A ++ G
Sbjct: 5140 AKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHG 5199
Query: 1603 LAVTKAKLQVFQR 1615
+ LQV +R
Sbjct: 5200 EIESNVNLQVDER 5212
Score = 73.3 bits (172), Expect = 8e-12
Identities = 90/392 (22%), Positives = 143/392 (36%), Gaps = 54/392 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGD 1280
KDS + + LN+ + + + L G +C A N GS S+S I+ E +
Sbjct: 4763 KDSPNVQTSFLDNTATLNIFKTD--RSLAGQYSCTATNPIGSASSSARLILTEGK----N 4816
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P L + GE C + G K+ W + + I + IS ++ +
Sbjct: 4817 PPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENS-AHL 4875
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
+ + +G Y C A N+ GK S LNI+ +P P
Sbjct: 4876 TVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE-RLIP--------------------P 4914
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
K L V TEG +LE + G V W + E+ ++ +I + T +L
Sbjct: 4915 SFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEI-TFKNNTLVLQ 4973
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+ + +D G + N G +AL SIV +E +KP
Sbjct: 4974 VRKAGMNDAGLYTCKVSNDAG-----SALCTSSIV-IKEPKKP----------------- 5010
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P F + + P V E E V G+ I W K + I+ +R
Sbjct: 5011 --PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVL 5068
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
++ K G Y CKA + G TK+K+ +
Sbjct: 5069 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 5100
Score = 68.5 bits (160), Expect = 2e-10
Identities = 88/381 (23%), Positives = 154/381 (40%), Gaps = 63/381 (16%)
Query: 1223 STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAP 1282
ST R++ +++++ N+ + TC+ N AG + SG V+E
Sbjct: 1943 STSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSF----- 1997
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
++ P + D + + G P KI WF ++ + + I + S +++
Sbjct: 1998 -LVKPGRQQAIPDST-VEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGS-TSFLNL 2054
Query: 1343 KEAFPEMAGIYKCTASNQFGKCS-TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
G Y C +N G S T +L E ++V + A +
Sbjct: 2055 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLE----------------ASK 2098
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM 1461
IVKA G RLE K G P+ +V W R EL S +Y++ + D +++ M
Sbjct: 2099 IVKA---------GDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFI-DSVAVIQM 2148
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
+ +D+G+ + EA N G T + S + IV ++P + + LK +
Sbjct: 2149 NNLSTEDSGDFICEAQNPAGST----SCSTKVIV-----KEPPVFSSFPPIVETLKNAE- 2198
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
V+ E SG P E++WYKD + +R+ +++ I +K T+
Sbjct: 2199 ------------------VSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIH 2240
Query: 1582 IKKATKDLEGTYTCKAVSDIG 1602
I G Y CKA +++G
Sbjct: 2241 ILNVDTSDIGEYHCKAQNEVG 2261
Score = 66.1 bits (154), Expect = 1e-09
Identities = 83/366 (22%), Positives = 137/366 (37%), Gaps = 62/366 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A N AG+ S S V+E P + L+ V+ + L C++ G P
Sbjct: 1595 GTYVCEARNDAGTASCSIELKVKEP-------PTFIRELKPVEVVKYSDVELECEVTGTP 1647
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
++ W N + I +++ T++ + S + +HI + P G Y+C SN+ G S C
Sbjct: 1648 PFEVTWLKNNREIRSSKKYTLTDRVS-VFNLHITKCDPSDTGEYQCIVSNEGG--SCSCS 1704
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+ E P +K + T + ++ G P
Sbjct: 1705 TRVALKE----------------------PPSFIKKIENTTTVLKSSAT-FQSTVAGSPP 1741
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
+ WL+ ++L + D + L + V +G +A N GV A L
Sbjct: 1742 ISITWLKDD-QILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFL 1800
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
V+ E Q KA +SV V E++ +T E + +G
Sbjct: 1801 LVQ-----------------EPAQIVEKA-KSVD----------VTEKDPMTLECVVAGT 1832
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P ++ W KD K I F + + N + I+ K G YT K +D G + A
Sbjct: 1833 PELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 1892
Query: 1610 LQVFQR 1615
L+V +
Sbjct: 1893 LRVLDQ 1898
Score = 65.7 bits (153), Expect = 2e-09
Identities = 83/366 (22%), Positives = 136/366 (37%), Gaps = 56/366 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C EN +G S S ++ E P + LE V G+ SL C++ G P
Sbjct: 4601 GQYNCYIENASGKDSCSAQILILEP-------PYFVKQLEPVKVSVGDSASLQCQLAGTP 4653
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+ W+ + + + ++ + + + +G Y C A N G+ S
Sbjct: 4654 EIGVSWYKGDTKLRPTTTYKM-HFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTF 4712
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L ++ + PS S + DV+E LP V + G
Sbjct: 4713 LTVQEQKLPPSFSRQ-------LRDVQETV-----GLPVV----------FDCAISGSEP 4750
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
V W + G L S Q LD+ T+ L + + + G+ A N +G ++ A L
Sbjct: 4751 ISVSWYKDGKPLKDSPNVQTSFLDN-TATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ E + P P F + P E FE +G
Sbjct: 4810 ILT------EGKNP-------------------PFFDIRLAPVDAVVGESADFECHVTGT 4844
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
++ W KD++ IR+ ++ I EN T+ K K G YTC AV+++G A+
Sbjct: 4845 QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQ 4904
Query: 1610 LQVFQR 1615
L + +R
Sbjct: 4905 LNIKER 4910
Score = 64.9 bits (151), Expect = 3e-09
Identities = 89/373 (23%), Positives = 142/373 (38%), Gaps = 64/373 (17%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM-DGERISLN 1302
+ K G TC+A N G S V+E P + LE + V GE I L
Sbjct: 2998 VGKGDSGQYTCQATNDVGKDMCSAQLSVKEP-------PKFVKKLEASKVAKQGESIQLE 3050
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CKI G P K+ WF N+ + + +S S + + I EA E +G Y C A N G
Sbjct: 3051 CKISGSPEIKVSWFRNDSELHESWKYNMSFINS-VALLTINEASAEDSGDYICEAHNGVG 3109
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEA 1422
S L ++ AP + P+ V +G + L+
Sbjct: 3110 DASCSTALTVK-------------------------APPVFTQKPSPVGALKGSDVILQC 3144
Query: 1423 KAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGV 1482
+ G P +V W++ ++ S +++I T++ + + D GE +A N +G
Sbjct: 3145 EISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHIL-NLEASDVGEYHCKATNEVG- 3202
Query: 1483 TATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTF 1542
+ + SV+ +++P P FVK++ + V
Sbjct: 3203 -SDTCSCSVK-------FKEP-------------------PRFVKKLSDTSTLIGDAVEL 3235
Query: 1543 EAIYSGNPTPEILWYKDN-KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
AI G ++W KD +VIR E I +N T + G Y C+ +D
Sbjct: 3236 RAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDA 3295
Query: 1602 GLAVTKAKLQVFQ 1614
G+ A L V +
Sbjct: 3296 GMRECSAVLTVLE 3308
Score = 64.9 bits (151), Expect = 3e-09
Identities = 94/399 (23%), Positives = 150/399 (37%), Gaps = 59/399 (14%)
Query: 1214 KDSHIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEE 1273
KD ++I + S + + + L +LE I +C EN AG I E
Sbjct: 3627 KDEYLISQ-SERCSITMTEKSTILEILESTIED--YAQYSCLIENEAGQ------DICEA 3677
Query: 1274 QTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ 1333
+ + P + PLE+ + GE +L CK+ G P +I W+ + +A + +
Sbjct: 3678 LVSVL-EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKM-QF 3735
Query: 1334 KSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTS 1393
K+ + + I + G Y C A N G ++ +L I+A + P + K
Sbjct: 3736 KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFA-------RKLK 3788
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD 1453
DV E T G + E + G QV W + G L Q +
Sbjct: 3789 DVHE---------------TLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVH 3833
Query: 1454 DGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
+ + L + + Q G+ A N LG ++ A L + E+ P
Sbjct: 3834 N-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL------SEHEVP---------- 3876
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
P F + + + E TF+ +G +I W KDN+ IR + +
Sbjct: 3877 ---------PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL 3927
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
EN T T+ K K G YTC A + G A+L V
Sbjct: 3928 VENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGV 3966
Score = 62.5 bits (145), Expect = 1e-08
Identities = 85/370 (22%), Positives = 137/370 (37%), Gaps = 56/370 (15%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N +K G +C EN AG G+ + T + P + LE G+ +SL
Sbjct: 2712 NSTKRDAGQYSCEIENEAGR-DVCGALV---STL---EPPYFVTELEPLEAAVGDSVSLQ 2764
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C++ G P + W+ + + + + + + + + +G Y C A N G
Sbjct: 2765 CQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLVFNKVNINDSGEYTCKAENSIG 2823
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEA 1422
S++ + I+ + PS + + D+E+ T G + L
Sbjct: 2824 TASSKTVFRIQERQLPPSFARQ-------LKDIEQ---------------TVGLPVTLTC 2861
Query: 1423 KAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGV 1482
+ G QV W R G LL+ E D + L + + +G+ A N LG
Sbjct: 2862 RLNGSAPIQVCWYRDGV-LLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGT 2920
Query: 1483 TATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTF 1542
++ A L+ R+P+ P F + + V E F
Sbjct: 2921 ASSSARLTA---------REPK----------------KSPFFDIKPVSIDVIAGESADF 2955
Query: 1543 EAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E +G I W KDNK IR + I N I K K G YTC+A +D+G
Sbjct: 2956 ECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG 3015
Query: 1603 LAVTKAKLQV 1612
+ A+L V
Sbjct: 3016 KDMCSAQLSV 3025
Score = 61.7 bits (143), Expect = 2e-08
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 12/215 (5%)
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
+ P I+ L VT+ EG+ R + + G +V W + ++ S +++ + +D T
Sbjct: 8 YPPAIITPLQDTVTS-EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TY 64
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
L + E Y +D G F A N +G ++ A LS+E+ PE + H Q
Sbjct: 65 QLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEA---------PESILHERIEQEIEM 115
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
++ P ++I P V + F P W+K + I ++ I + +
Sbjct: 116 EMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 175
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
++ I + G YTCKA ++ G A L V
Sbjct: 176 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 210
Score = 61.7 bits (143), Expect = 2e-08
Identities = 88/363 (24%), Positives = 140/363 (38%), Gaps = 59/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC AEN AGS ++ G IV+E I A L+ V G+ +L + G P
Sbjct: 657 GKYTCLAENEAGSQTSVGELIVKEPAKIIERAELI-------QVTAGDPATLEYTVAGTP 709
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
K W+ + + + ++ IS K+ + ++ A +G Y SN+ G S E
Sbjct: 710 ELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 768
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+V + D+ AP K L V + G RL+ K G
Sbjct: 769 F---------TVLDRDI------------APFFTKPLRNVDSVVNGTC-RLDCKIAGSLP 806
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
+V W + G E+ S Y+I + +GT+ L + V +D G A N +G + AL
Sbjct: 807 MRVSWFKDGKEIAASDRYRIAFV-EGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 865
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
V+ P +VT K+++P V ++ + G+
Sbjct: 866 IVQ--------EPPSFVTKPGS---------------KDVLP-----GSAVCLKSTFQGS 897
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
I W+K NK + + I + ++ + GTYTCK + G A
Sbjct: 898 TPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSAN 957
Query: 1610 LQV 1612
L V
Sbjct: 958 LFV 960
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/380 (24%), Positives = 143/380 (37%), Gaps = 66/380 (17%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD- 1295
LN+ + SK G TC N GS S + +V E P + LE + ++
Sbjct: 2052 LNLYSVDASKT--GQYTCHVTNDVGSDSCTTMLLVTEP-------PKFVKKLEASKIVKA 2102
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G+ L CKI G P ++ WF NE + + ++ S + I + E +G + C
Sbjct: 2103 GDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDS-VAVIQMNNLSTEDSGDFIC 2161
Query: 1356 TASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEG 1415
A N G ST C + E P + + P +V T +
Sbjct: 2162 EAQNPAG--STSCSTKVIVKE-----------------------PPVFSSFPPIVETLKN 2196
Query: 1416 KLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFE 1475
+ LE + G P +V W + +L S +Y+I + TSI + V D GE +
Sbjct: 2197 AEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHIL-NVDTSDIGEYHCK 2255
Query: 1476 AYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVH 1535
A N +G ++ V T + ++P P FV ++ V
Sbjct: 2256 AQNEVG---------SDTCVCTVKLKEP-------------------PRFVSKLNSLTVV 2287
Query: 1536 EEEIVTFEAIYSGNPTPEILWYKD-NKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
E +A G + W K+ +VIR E I EN T KA G Y
Sbjct: 2288 AGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYI 2347
Query: 1595 CKAVSDIGLAVTKAKLQVFQ 1614
C+ +D G+ A L V +
Sbjct: 2348 CQIKNDGGMRENMATLMVLE 2367
Score = 60.5 bits (140), Expect = 6e-08
Identities = 86/378 (22%), Positives = 142/378 (37%), Gaps = 62/378 (16%)
Query: 1239 VLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGE 1297
VLE N+S + G TC A N AGS S+S S V+E P+ + G
Sbjct: 4027 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE-------PPIFRKKPHPIETLKGA 4079
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L C++ G P + W+ +++ + + + I ++ L IHI G Y+C A
Sbjct: 4080 DVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIHILNVDAADIGEYQCKA 4138
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
+N G S C+ +I + PR VK L + ++T GK
Sbjct: 4139 TNDVG--SDTCVGSIAL----------------------KAPPRFVKKL-SDISTVVGKE 4173
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
++L+ G V W + E+++ ++ + + L V + G+ +
Sbjct: 4174 VQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIK 4233
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
N G+ A LSV E KPE ++K T
Sbjct: 4234 NDAGMQECFATLSVLEPATIVE--KPE----------SIKVTTG---------------- 4265
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
+ T E +G P W+KD K + +D ++ I + I G Y+ +
Sbjct: 4266 DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEV 4325
Query: 1598 VSDIGLAVTKAKLQVFQR 1615
+ +G A LQV R
Sbjct: 4326 QNPVGKDSCTASLQVSDR 4343
Score = 60.1 bits (139), Expect = 8e-08
Identities = 64/276 (23%), Positives = 114/276 (41%), Gaps = 34/276 (12%)
Query: 1218 IIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
++ KD L + + L +L+ + S IG C A N G+ S+S I+ E
Sbjct: 3819 VLLKDDANLQTSFVHNVATLQILQTDQSH--IGQYNCSASNPLGTASSSAKLILSEHEV- 3875
Query: 1278 DGDAPLV-LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
P L P+ + GE + C + G KI W + + I + ++ ++
Sbjct: 3876 ---PPFFDLKPVSVDLAL-GESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENT 3931
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+K + AG Y C ASN GK S L ++
Sbjct: 3932 ATLTVLKVGKGD-AGQYTCYASNIAGKDSCSAQLGVQE---------------------- 3968
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
PR +K L + + R E K G P+ +V W + TE+ +S+++++ + D
Sbjct: 3969 --PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFV-DSV 4025
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
++L M + +D+G+ EA+N G ++ +L V+
Sbjct: 4026 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 4061
Score = 60.1 bits (139), Expect = 8e-08
Identities = 86/365 (23%), Positives = 134/365 (36%), Gaps = 63/365 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC+ +N AG + V E A +V P E+ V G+ +L C + G P
Sbjct: 4226 GKYTCQIKNDAGMQECFATLSVLEP------ATIVEKP-ESIKVTTGDTCTLECTVAGTP 4278
Query: 1310 WPKIDWFHNEKLIETARDITIS--RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTE 1367
WF + K + + IS + SGL I++ P +G+Y N GK S
Sbjct: 4279 ELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVA---PSDSGVYSFEVQNPVGKDSCT 4335
Query: 1368 CILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L + PS T ++E G + +E K G
Sbjct: 4336 ASLQVSDRTVPPSF----------TRKLKE------------TNGLSGSSVVMECKVYGS 4373
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P V W +G E+ +YQ L D T LT+ + + D+G+ A N G A
Sbjct: 4374 PPISVSWFHEGNEISSGRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSA 4432
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
L+V R+P P+FV++ P V VTF +I
Sbjct: 4433 PLTV---------REP-------------------PSFVQKPDPMDVLTGTNVTFTSIVK 4464
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P + W+K + + +R + +++ + G YTC ++ G A
Sbjct: 4465 GTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCT 4524
Query: 1608 AKLQV 1612
L +
Sbjct: 4525 THLYI 4529
Score = 59.7 bits (138), Expect = 1e-07
Identities = 80/366 (21%), Positives = 141/366 (38%), Gaps = 62/366 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C A N GS S S +++E P + LE ++ G L C++ G
Sbjct: 471 GSYSCEAVNDVGSDSCSTEIVIKEP-------PSFIKTLEPADIVRGTNALLQCEVSGTG 523
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
+I WF ++K I +++ + QKS +C + I G Y+C +N+ GKC C+
Sbjct: 524 PFEISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYECVVANEVGKCG--CM 580
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
T ++E P VK + ++ G+ + L+A G
Sbjct: 581 ---------------------ATHLLKE-PPTFVKKVDDLI-ALGGQTVTLQAAVRGSEP 617
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
V W++ G E+++ +G ++L +P+V G+ A N G ++ L
Sbjct: 618 ISVTWMK-GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGEL 676
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
V ++P + EL ++ T P T E +G
Sbjct: 677 IV---------KEPAKIIERAEL---IQVTAGDP----------------ATLEYTVAGT 708
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P + WYKD + + +++ I K N A G YT + +++G + +
Sbjct: 709 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 768
Query: 1610 LQVFQR 1615
V R
Sbjct: 769 FTVLDR 774
Score = 59.3 bits (137), Expect = 1e-07
Identities = 86/364 (23%), Positives = 143/364 (39%), Gaps = 65/364 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G +C N AGS S + V+E + L + +V G I L G P
Sbjct: 3567 GDYSCLVTNDAGSASCTTHLFVKEPATF-------VKRLADFSVETGSPIVLEATYTGTP 3619
Query: 1310 WPKIDWFHNEKLIETARDITIS-RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+ W +E LI + +I+ +KS + E I E+ E Y C N+ G+ E
Sbjct: 3620 PISVSWIKDEYLISQSERCSITMTEKSTILE--ILESTIEDYAQYSCLIENEAGQDICEA 3677
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ SV E P ++ L V G+ L+ K G P
Sbjct: 3678 LV---------SVLE---------------PPYFIEPLEHVEAVI-GEPATLQCKVDGTP 3712
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
+ ++ W ++ T+L + Y++ + + + L + +V D GE +A N +G A+ A
Sbjct: 3713 EIRISWYKEHTKLRSAPAYKM-QFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAV 3771
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE--EIVTFEAIY 1546
L +KA + P F +++ + VHE V FE
Sbjct: 3772 L-------------------------VIKARKLPPFFARKL--KDVHETLGFPVAFECRI 3804
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
+G+ ++ WYKD +++ D N T I + + G Y C A + +G A +
Sbjct: 3805 NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASS 3864
Query: 1607 KAKL 1610
AKL
Sbjct: 3865 SAKL 3868
Score = 58.8 bits (136), Expect = 2e-07
Identities = 75/346 (21%), Positives = 131/346 (37%), Gaps = 61/346 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG SG V+E P + ++ V R+ L + G
Sbjct: 1408 GTYTCSATNKAGHNQCSGHLTVKEP-------PYFVEKPQSQDVNPNTRVQLKALVGGTA 1460
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
I WF + K + + ++ + + + + A +G Y C SN G +++
Sbjct: 1461 PMTIKWFKDNKELHSGAARSVWKDDTST-SLELFAAKATDSGTYICQLSNDVGTATSKAT 1519
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L ++ P+ +K V+ G+ E + G PK
Sbjct: 1520 LFVKE------------------------PPQFIKKPSPVLVLRNGQSTTFECQITGTPK 1555
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
+V W G E+ ++ I +D G + + +++G V EA N G A+
Sbjct: 1556 IRVSWYLDGNEITAIQKHGISFID-GLATFQISGARVENSGTYVCEARNDAGT----ASC 1610
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
S+E V ++P PTF++E+ P V + V E +G
Sbjct: 1611 SIELKV-----KEP-------------------PTFIRELKPVEVVKYSDVELECEVTGT 1646
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTC 1595
P E+ W K+N+ IR+ +++ + ++ + I K G Y C
Sbjct: 1647 PPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC 1692
Score = 58.4 bits (135), Expect = 2e-07
Identities = 74/360 (20%), Positives = 140/360 (38%), Gaps = 54/360 (15%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTS-GSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
+S ++ V A + V+ GSSI + + + P + +E+T+ + G +
Sbjct: 1113 VSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLR-EPPSFIKKIESTSSLRGGTAAFQ 1171
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
+ G + W + I +I ++ + + + +++ + G Y C A N G
Sbjct: 1172 ATLKGSLPITVTWLKDSDEITEDDNIRMTFENN-VASLYLSGIEVKHDGKYVCQAKNDAG 1230
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEA 1422
I+ + SV E +++E S + T+G L+
Sbjct: 1231 ---------IQRCSALLSVKEPATITEEAVS----------------IDVTQGDPATLQV 1265
Query: 1423 KAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGV 1482
K G + +W + G EL ++Y+I + D SIL + + D+GE FE N +G
Sbjct: 1266 KFSGTKEITAKWFKDGQELTLGSKYKI-SVTDTVSILKIISTEKKDSGEYTFEVQNDVGR 1324
Query: 1483 TATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTF 1542
++ A ++V ++ + K LK S+ + +
Sbjct: 1325 SSCKARINVLDLIIPPSFTK------------KLKKMDSI-------------KGSFIDL 1359
Query: 1543 EAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
E I +G+ I W+KD++ I E++ +N I + GTYTC A + G
Sbjct: 1360 ECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 1419
Score = 57.6 bits (133), Expect = 4e-07
Identities = 80/382 (20%), Positives = 150/382 (39%), Gaps = 63/382 (16%)
Query: 1222 DSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA 1281
+S + + R + + +L +L + G TC+A N GSVS + + V E
Sbjct: 163 ESDKCSIRSSKYISSLEILRTQVVD--CGEYTCKASNEYGSVSCTATLTVTEAY-----P 215
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L+ ++ T G+ C + G P + W + + + + IS ++ +
Sbjct: 216 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHI-LE 274
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
+ + G+Y C ASN+FG + + +++ +K ++E P
Sbjct: 275 LSNLTIQDRGVYSCKASNKFG----------------ADICQAELIIIDKPHFIKELEP- 317
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM 1461
V + K + LE + K V W + G +L +Y+I +D + L +
Sbjct: 318 --------VQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKI-CFEDKIATLEI 368
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
P D+G V A N G ++ A ++V R+P
Sbjct: 369 PLAKLKDSGTYVCTASNEAGSSSCSATVTV---------REP------------------ 401
Query: 1522 VPTFVKEIIPERVH-EEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
P+FVK++ P + E G+P ++ W+K+NK + + +
Sbjct: 402 -PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAIL 460
Query: 1581 TIKKATKDLEGTYTCKAVSDIG 1602
I + G+Y+C+AV+D+G
Sbjct: 461 DITDVKVEDSGSYSCEAVNDVG 482
Score = 56.0 bits (129), Expect = 1e-06
Identities = 76/333 (22%), Positives = 127/333 (38%), Gaps = 55/333 (16%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + L++ + G + L C++ G + WF + I + S ++ +C ++
Sbjct: 3406 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCTLN 3464
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
+ P GIY C A+N G S EC V +V E S E+T D E P
Sbjct: 3465 LSLLEPSDTGIYTCVAANVAG--SDEC-------SAVLTVQEPP--SFEQTPDSVEVLPG 3513
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM 1461
+ +V+ G P +V+W + EL+ I L+D + L +
Sbjct: 3514 MSLTFTSVIR--------------GTPPFKVKWFKGSRELVPGESCNIS-LEDFVTELEL 3558
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQS 1521
EV ++G+ S + T + TH+ + A
Sbjct: 3559 FEVQPLESGDY--------------------SCLVTNDAGSASCTTHLFVKEPA------ 3592
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
TFVK + V + EA Y+G P + W KD +I ER I E T
Sbjct: 3593 --TFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILE 3650
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
I ++T + Y+C ++ G + +A + V +
Sbjct: 3651 ILESTIEDYAQYSCLIENEAGQDICEALVSVLE 3683
Score = 54.8 bits (126), Expect = 3e-06
Identities = 72/321 (22%), Positives = 120/321 (37%), Gaps = 52/321 (16%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
TV GE +L CK+ G P ++W+ + KL+ +++ S + + I + AG
Sbjct: 2379 TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK-ISSLRILSVERQDAG 2437
Query: 1352 IYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVT 1411
Y N GK S ++++ PS + R +K V+
Sbjct: 2438 TYTFQVQNNVGKSSCTAVVDVSDRAVPPSFT------------------RRLKNTGGVL- 2478
Query: 1412 TTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE 1471
G LE K G V W + T+++ +YQ D L + + D G
Sbjct: 2479 ---GASCILECKVAGSSPISVAWFHEKTKIVSGAKYQ-TTFSDNVCTLQLNSLDSSDMG- 2533
Query: 1472 IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP 1531
N+ V A +A G+ E R A+ Q P+FVKE P
Sbjct: 2534 ------NYTCVAANVA--------GSDECR-------------AVLTVQEPPSFVKEPEP 2566
Query: 1532 ERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V + VTF ++ G P ++ W++ + + +R I ++ + G
Sbjct: 2567 LEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSG 2626
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
YTC ++ G A +L V
Sbjct: 2627 EYTCVVSNNAGQASCTTRLFV 2647
Score = 54.4 bits (125), Expect = 4e-06
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 1514 AALKATQSVPTFVKEIIPER-VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE 1572
+A Q P F+K++ P R V ++E +E G+P ++LWYKD I+ +F +
Sbjct: 3961 SAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMS 4020
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
++ + + + G YTC+A + G A + L+V
Sbjct: 4021 FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 4060
Score = 54.0 bits (124), Expect = 5e-06
Identities = 62/258 (24%), Positives = 110/258 (42%), Gaps = 38/258 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TCRA N GS +SG+ IV+E P + + V+ G + L G
Sbjct: 846 GNFTCRATNSVGSKDSSGALIVQE-------PPSFVTKPGSKDVLPGSAVCLKSTFQGST 898
Query: 1310 WPKIDWFHNEKLIETARDITISRQK-SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
I WF K + + I+++ E+++ + +G Y C SN G EC
Sbjct: 899 PLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKT--SDSGTYTCKVSNVAG--GVEC 954
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP-RIVKALPTVVTTTEGKLIRLEAKAIGI 1427
N+ E + VE+ P +++K +G +L K G
Sbjct: 955 SANL--------------FVKEPATFVEKLEPSQLLK---------KGDATQLACKVTGT 991
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P ++ W E+ +S+++++ + + T++L + +V +D+GE + EA N G +
Sbjct: 992 PPIKITWFANDREIKESSKHRMSFV-ESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSS 1050
Query: 1488 ALSV-ESIVGTQEYRKPE 1504
+ V ES T+E++ E
Sbjct: 1051 IVIVKESPYFTKEFKPIE 1068
Score = 53.2 bits (122), Expect = 9e-06
Identities = 79/389 (20%), Positives = 145/389 (37%), Gaps = 62/389 (15%)
Query: 1214 KDSHIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEE 1273
KD I+++D + + L + ++ G TC+A+N +G +V+E
Sbjct: 1748 KDDQILDEDDNVYIS-FVDSVATLQI--RSVDNGHSGRYTCQAKNESGVERCYAFLLVQE 1804
Query: 1274 QTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ 1333
I A ++ V + + ++L C + G P K+ W + K I +R ++S +
Sbjct: 1805 PAQIVEKA-------KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFE 1857
Query: 1334 KSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTS 1393
+ + I+ + +G Y N FG S + L + PS
Sbjct: 1858 -NNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPS------------- 1903
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD 1453
F ++ K + G I +E K G +W + G E+ S +Y++ +
Sbjct: 1904 ----FTKKLTK-----MDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHE 1954
Query: 1454 DGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
S L + + +DT + N G A L+V+ P ++ Q
Sbjct: 1955 RSVS-LEVNNLELEDTANYTCKVSNVAGDDACSGILTVK--------EPPSFLVKPGRQQ 2005
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
A IP + V F+AI G P +I W+KD+ + + + I
Sbjct: 2006 A---------------IP-----DSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL 2045
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ + + + G YTC +D+G
Sbjct: 2046 EGSTSFLNLYSVDASKTGQYTCHVTNDVG 2074
Score = 52.8 bits (121), Expect = 1e-05
Identities = 85/367 (23%), Positives = 133/367 (36%), Gaps = 62/367 (16%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G TC A N AGS V+E P + E V+ G+ ++ I G
Sbjct: 2532 MGNYTCVAANVAGSDECRAVLTVQEP-------PSFVKEPEPLEVLPGKNVTFTSVIRGT 2584
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P K++WF + + I + + + E+ + +G Y C SN G+ S C
Sbjct: 2585 PPFKVNWFRGARELVKGDRCNIYFEDT-VAELELFNIDISQSGEYTCVVSNNAGQAS--C 2641
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
+ E + LSD + GK I LE+ G
Sbjct: 2642 TTRLFVKEPAAFLKR---LSDH--------------------SVEPGKSIILESTYTGTL 2678
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
V W + G + S + I + T IL + + D G+ E N G A
Sbjct: 2679 PISVTWKKDGFNITTSEKCNIVTTEK-TCILEILNSTKRDAGQYSCEIENEAGRDVCGA- 2736
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
+V T E P +VT +E L+AA+ + V+ + +G
Sbjct: 2737 -----LVSTLE--PPYFVTELEPLEAAV--------------------GDSVSLQCQVAG 2769
Query: 1549 NPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P + WYK + +R + N T K + G YTCKA + IG A +K
Sbjct: 2770 TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT 2829
Query: 1609 KLQVFQR 1615
++ +R
Sbjct: 2830 VFRIQER 2836
Score = 52.4 bits (120), Expect = 2e-05
Identities = 39/141 (27%), Positives = 64/141 (45%), Gaps = 12/141 (8%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM-DGERISLNCKILGR 1308
G C A N AGS S S + V E P + ++ + +M GE L+CK+ G
Sbjct: 377 GTYVCTASNEAGSSSCSATVTVREP-------PSFVKKVDPSYLMLPGESARLHCKLKGS 429
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG--KCST 1366
P ++ WF N K + + + + S + I + E +G Y C A N G CST
Sbjct: 430 PVIQVTWFKNNKELSESNTVRMYFVNSEAI-LDITDVKVEDSGSYSCEAVNDVGSDSCST 488
Query: 1367 ECILNIEAYEYVPSVSEEDVL 1387
E ++ E ++ ++ D++
Sbjct: 489 EIVIK-EPPSFIKTLEPADIV 508
Score = 50.8 bits (116), Expect = 5e-05
Identities = 25/88 (28%), Positives = 45/88 (51%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F KE P V +E V A +G P EI W+KDN ++R+ ++ +++ + I
Sbjct: 1058 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI 1117
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
K G Y C+ +++G ++ A++
Sbjct: 1118 LKFVAADAGEYQCRVTNEVGSSICSARV 1145
Score = 50.0 bits (114), Expect = 8e-05
Identities = 62/250 (24%), Positives = 102/250 (40%), Gaps = 35/250 (14%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ IG C+A+N GS + + ++E P ++ L + TV+ GE L
Sbjct: 2243 NVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP-------PRFVSKLNSLTVVAGEPAELQ 2295
Query: 1303 CKILGRPWPKIDWF-HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
I G + W E++I + +I I+ ++ + + +A P AG Y C N
Sbjct: 2296 ASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATLQFAKAEPANAGKYICQIKNDG 2354
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L V E V+ VE+ P +T T G+ LE
Sbjct: 2355 GMRENMATL---------MVLEPAVI-------VEKAGP---------MTVTVGETCTLE 2389
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K G P+ V W + G +LL S++ + S L + V + D G F+ N++G
Sbjct: 2390 CKVAGTPELSVEWYKDG-KLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVG 2448
Query: 1482 VTATIAALSV 1491
++ A + V
Sbjct: 2449 KSSCTAVVDV 2458
Score = 49.6 bits (113), Expect = 1e-04
Identities = 95/493 (19%), Positives = 186/493 (37%), Gaps = 30/493 (6%)
Query: 36 DHKTQIQSTSTKKVEPTTGKASYSTT-EETNMLKVENIQDTETKNITTVPWRKREQLDMH 94
+ K + KK P + S T EE + E + + + + +
Sbjct: 6102 EEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWS 6161
Query: 95 FKKEDT-LEIKHWRRSRPEQNKDTEHTS--MIGXXXXXXXXXXXXVFERGVIEEHVKVQE 151
+ +E+ + I +R E+ ++ E T ++ + + V E +V E
Sbjct: 6162 YSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTE 6221
Query: 152 VVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEE 211
E K+ KPK ++ ++ E + E V K E P++ E
Sbjct: 6222 RQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEK----KVPAPVPKKEKVP--PPKVPE 6275
Query: 212 SLEEVGPTKGVNEPEVCHWRKPKTSEI----LKDKNEEEIRVQEMKKQSTKALEVKDESK 267
++ P K V P+V +P +++ ++ EE++ V KK++ V +E K
Sbjct: 6276 EPKKPVPEKKV-PPKVIKMEEPLPAKVTEKHMQITQEEKVLVAVTKKEAPPKARVPEEPK 6334
Query: 268 QKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNERQITEK 327
+ +P ++ +KL+P + E+ P K+ + + V+++ + E + E I E+
Sbjct: 6335 RAVP-EEKVLKLKPKREEEPP---AKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEE 6390
Query: 328 KESLQ--ETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXX 385
KE E + ++ + E + KE E +E +
Sbjct: 6391 KERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEY 6450
Query: 386 XXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAI----KLRPTKMEKTPIEKE 441
PV +E T+ + K ++P + + KL+P K P E +
Sbjct: 6451 ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP-PKVPEEPK 6509
Query: 442 K-FED-ITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGK 499
K FE+ I + T+++ +++TE + + EE P E P +
Sbjct: 6510 KVFEEKIHISITKREK--EQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 6567
Query: 500 RQPKEETPQEEVV 512
+P+E +EEVV
Sbjct: 6568 LEPEEVAFEEEVV 6580
Score = 48.0 bits (109), Expect = 3e-04
Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 37/268 (13%)
Query: 1218 IIEKDSTELTPRI---IQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEE 1273
I +KD L+P I + ++LE N++ GV +C+A N G+ I +
Sbjct: 248 IWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASN------KFGADICQA 301
Query: 1274 QTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ 1333
+ I D P + LE +++ L C++ + W + + + +D I +
Sbjct: 302 ELIII-DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFE 360
Query: 1334 KSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTS 1393
+ + I A + +G Y CTASN+ G S+ C + E
Sbjct: 361 DK-IATLEIPLAKLKDSGTYVCTASNEAG--SSSCSATVTVRE----------------- 400
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELD 1453
P VK + G+ RL K G P QV W + EL +S ++ +
Sbjct: 401 -----PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFV- 454
Query: 1454 DGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ +IL + +V +D+G EA N +G
Sbjct: 455 NSEAILDITDVKVEDSGSYSCEAVNDVG 482
Score = 48.0 bits (109), Expect = 3e-04
Identities = 42/165 (25%), Positives = 64/165 (38%), Gaps = 9/165 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N++ GV + +N G S + S V ++T P L+ T + G + +
Sbjct: 4312 NVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTV----PPSFTRKLKETNGLSGSSVVME 4367
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CK+ G P + WFH I + R + C + + +G Y C A+N G
Sbjct: 4368 CKVYGSPPISVSWFHEGNEISSGRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIATNMAG 4426
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
S EC + E V + D + D T F IVK P
Sbjct: 4427 --SDECSAPLTVREPPSFVQKPDPM-DVLTGTNVTFT-SIVKGTP 4467
Score = 47.2 bits (107), Expect = 6e-04
Identities = 73/333 (21%), Positives = 120/333 (36%), Gaps = 55/333 (16%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ +E V G C+I P + WF + I + +I R + +
Sbjct: 120 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSL 178
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI-EAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I G Y C ASN++G S L + EAY
Sbjct: 179 EILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY------------------------ 214
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P + P +TT GK + G P + W + G L S ++I + ++ IL
Sbjct: 215 PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAEN-KHIL 273
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
+ + D G +A N G A L + KP ++ +E +Q+A+
Sbjct: 274 ELSNLTIQDRGVYSCKASNKFGADICQAELII--------IDKPHFIKELEPVQSAINK- 324
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
K + +V E+ VT + W KD + + + + I ++ T
Sbjct: 325 -------KVHLECQVDEDRKVT------------VTWSKDGQKLPPGKDYKICFEDKIAT 365
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A GTY C A ++ G + A + V
Sbjct: 366 LEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 398
Score = 47.2 bits (107), Expect = 6e-04
Identities = 26/90 (28%), Positives = 43/90 (47%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P FV++ + V+ V +A+ G I W+KDNK + + + + T+ +
Sbjct: 1433 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLEL 1492
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
A GTY C+ +D+G A +KA L V
Sbjct: 1493 FAAKATDSGTYICQLSNDVGTATSKATLFV 1522
Score = 46.4 bits (105), Expect = 0.001
Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
Query: 1514 AALKATQSV---PTFVKEIIPERV-HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
A KAT V P F+K+ P V + TFE +G P + WY D I ++
Sbjct: 1514 ATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKH 1573
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I + T I A + GTY C+A +D G A +L+V
Sbjct: 1574 GISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKV 1616
Score = 46.0 bits (104), Expect = 0.001
Identities = 26/106 (24%), Positives = 47/106 (44%)
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
+++ AL + P F++ + E T + G P I WYK++ +R+ +
Sbjct: 3672 QDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAY 3731
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
++ K N + I K G Y+CKA + +G + A L + R
Sbjct: 3732 KMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR 3777
Score = 44.4 bits (100), Expect = 0.004
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 12/138 (8%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDG 1296
+N+LEE+ S D TC A N AGS S V E P + + V+ G
Sbjct: 4406 VNMLEESDSGDY----TCIATNMAGSDECSAPLTVREP-------PSFVQKPDPMDVLTG 4454
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCT 1356
++ + G P + WF + +S + S + E+ + + +G Y C
Sbjct: 4455 TNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDS-VAELELFDVDTSQSGEYTCI 4513
Query: 1357 ASNQFGKCSTECILNIEA 1374
SN+ GK S L I+A
Sbjct: 4514 VSNEAGKASCTTHLYIKA 4531
Score = 43.6 bits (98), Expect = 0.007
Identities = 70/316 (22%), Positives = 130/316 (41%), Gaps = 31/316 (9%)
Query: 207 PRLEESLEEVGPTKGVNEPEVCHWRKPKT-SEILKDKNEEEIRVQEMKKQSTKALEVKDE 265
P + E EE P+ +PEV R P+ E++ +K ++ KK ++V +
Sbjct: 7244 PEVFEEPEE-SPSAPPKKPEVPPVRVPEVPKEVVPEK---KVPAAPPKKPEVTPVKVPEA 7299
Query: 266 SKQKIPWTQEAI------KLRPTKVEKSPI----EKEKIEDVALKPVRKDSLMDEKSSEI 315
K+ +P + + ++ PTKV + P EK+ E + KP + E+ E+
Sbjct: 7300 PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEV 7359
Query: 316 SELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKT 375
+ + ++ E+ E Q+ KN + E +++ K+ + + EV +
Sbjct: 7360 ALEEPPAEVVEEPEPAAPPQVTVPPKNPVPE----KKAPAVVAKKPELPPVKVPEVPKEV 7415
Query: 376 VRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEK 435
V KP K + ++ + K K ++P E + ++ K
Sbjct: 7416 VPEKKVPLVVPK-----KPEAPPAKVPEVPKEVVPEK---KVAVPKKPEVPPAKVPEVPK 7467
Query: 436 TPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKW 495
P+ +EK P R +S E+ EE + ++I EE KP V+E PE
Sbjct: 7468 KPVLEEK--PAVPVPERAESPPPEVYEEPEEIAPE-EEIAPEEEKPVPVAEEEEPEVPP- 7523
Query: 496 PTGKRQPKEETPQEEV 511
P +PK+ P+++V
Sbjct: 7524 PAVPEEPKKIIPEKKV 7539
Score = 42.7 bits (96), Expect = 0.012
Identities = 48/212 (22%), Positives = 80/212 (37%), Gaps = 27/212 (12%)
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
RI++ P +T T G LE G P+ +W + G EL +++ I ++ S L
Sbjct: 3311 RIIEK-PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVAS-LK 3368
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+P D G FE N +G + ++ V + P ++ ++++ A L A+
Sbjct: 3369 IPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV-----SDRIVPPSFIRKLKDVNAILGAS- 3422
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
V E SG+ + W++D I + + EN T
Sbjct: 3423 -------------------VVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTL 3463
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ G YTC A + G A L V
Sbjct: 3464 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 3495
Score = 42.3 bits (95), Expect = 0.016
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 8/116 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ TC A N AGS S V+E + P ++ V+ G ++ I G P
Sbjct: 3474 GIYTCVAANVAGSDECSAVLTVQEPPSFE-QTP------DSVEVLPGMSLTFTSVIRGTP 3526
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
K+ WF + + IS + + E+ + E P +G Y C +N G S
Sbjct: 3527 PFKVKWFKGSRELVPGESCNISLE-DFVTELELFEVQPLESGDYSCLVTNDAGSAS 3581
Score = 42.3 bits (95), Expect = 0.016
Identities = 83/392 (21%), Positives = 161/392 (41%), Gaps = 32/392 (8%)
Query: 142 VIEEHVKVQEVVETKLWRKPKTISEKKDLLQV--STHEDTNILKVENLESVNVDTTSSKL 199
+I+ K +EV + RK + EK+ + + + H++ + +E+ E D +
Sbjct: 5692 IIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVF-IESFEEP-YDELEVEP 5749
Query: 200 ETKSWRKPRLEESLEEVGPTKGVNEPEVCH-WRKP--KTSEILK-----DKNEEEIRVQE 251
T+ + +P EE E+ K + EV W + + E + D+ EEE
Sbjct: 5750 YTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAY 5809
Query: 252 MKKQSTKAL-EVKDES-KQKIPWTQEAIKLRPT-KVEKSPIEKEKIEDVALKPVRKDSLM 308
+++ + EV +ES ++K+P K P KV K P+ EKIE + + + ++ +
Sbjct: 5810 QEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVI-EKIEKTSRR-MEEEKVQ 5867
Query: 309 DEKSSEISE--LQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEI 366
K E+S+ + + T +E + E ++ K+ ++SEE + +
Sbjct: 5868 VTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKM---VISEEKMFFASHTEEEVSV 5924
Query: 367 TQKEVALKTVRXXXXXXXXXXXXXSLKPVLTT-EKESKETEDRINTKDTRKPSIPWTQEA 425
T EV + V V EK + E + +P P E
Sbjct: 5925 TVPEVQKEIVTEEKIHVAVSKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEV 5984
Query: 426 IKLRPTKMEKTPI---EKE-----KFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKE 477
K +P EK P+ +KE K ++ KP ++ + + ++ A + + +++K
Sbjct: 5985 PK-KPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKG 6043
Query: 478 EHKPDKVSENNAPEERKWPTGKRQPKEETPQE 509
+K++ EE P PK++ P+E
Sbjct: 6044 VVTEEKITIVTQREESPPPAVPEIPKKKVPEE 6075
Score = 41.9 bits (94), Expect = 0.022
Identities = 32/145 (22%), Positives = 62/145 (42%), Gaps = 11/145 (7%)
Query: 1239 VLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQ---------TCIDGDAPLVLAPL 1288
VLE +++K G C+A N AGS +T ++++ +DG V P
Sbjct: 5067 VLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP- 5125
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
++ V++ + K+ G P P + W + QK ++ I++
Sbjct: 5126 QSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKT 5185
Query: 1349 MAGIYKCTASNQFGKCSTECILNIE 1373
+G+Y+C A N+ G+ + L ++
Sbjct: 5186 DSGLYRCVAFNEHGEIESNVNLQVD 5210
Score = 41.5 bits (93), Expect = 0.029
Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 15/170 (8%)
Query: 1236 ALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT-VM 1294
AL + E ++D G C A N G S S T + AP V + +
Sbjct: 3085 ALLTINEASAEDS-GDYICEAHNGVGDASCS--------TALTVKAPPVFTQKPSPVGAL 3135
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C+I G P ++ W + K + ++ I+ K +HI G Y
Sbjct: 3136 KGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTNLHILNLEASDVGEYH 3194
Query: 1355 CTASNQFGKCSTECILNI-EAYEYVPSVSEEDVL---SDEKTSDVEEFAP 1400
C A+N+ G + C + E +V +S+ L + E + VE F P
Sbjct: 3195 CKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQP 3244
Score = 40.7 bits (91), Expect = 0.050
Identities = 56/260 (21%), Positives = 98/260 (37%), Gaps = 35/260 (13%)
Query: 1234 LKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
+ +L +L ++ + G T + +N G S + V ++ P L+NT
Sbjct: 2423 ISSLRIL--SVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAV----PPSFTRRLKNTGG 2476
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
+ G L CK+ G + WFH + K++ A+ T +C + + G
Sbjct: 2477 VLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF--SDNVCTLQLNSLDSSDMGN 2534
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G +L ++ E S V+E P ++ LP
Sbjct: 2535 YTCVAANVAGSDECRAVLTVQ----------------EPPSFVKE--PEPLEVLP----- 2571
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
GK + + G P +V W R EL++ I +D + L + + +GE
Sbjct: 2572 --GKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELELFNIDISQSGEY 2628
Query: 1473 VFEAYNHLGVTATIAALSVE 1492
N+ G + L V+
Sbjct: 2629 TCVVSNNAGQASCTTRLFVK 2648
Score = 39.5 bits (88), Expect = 0.12
Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 1509 MEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER 1568
M E A L + V++ P V E T E +G P + WYKD K++ + ++
Sbjct: 2356 MRENMATLMVLEPA-VIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQK 2414
Query: 1569 FIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
++ I + GTYT + +++G + A + V R
Sbjct: 2415 HKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDR 2461
Score = 39.1 bits (87), Expect = 0.15
Identities = 22/99 (22%), Positives = 44/99 (44%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN 1573
+AL + + T +E + V + + T + +SG W+KD + + ++ I
Sbjct: 1235 SALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISV 1294
Query: 1574 KENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + I K G YT + +D+G + KA++ V
Sbjct: 1295 TDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINV 1333
Score = 37.9 bits (84), Expect = 0.35
Identities = 22/90 (24%), Positives = 38/90 (42%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F+K+I F+A G+ + W KD+ I D+ + + N + +
Sbjct: 1151 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 1210
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+G Y C+A +D G+ A L V
Sbjct: 1211 SGIEVKHDGKYVCQAKNDAGIQRCSALLSV 1240
Score = 35.5 bits (78), Expect = 1.9
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
L +E I ++ K E+ + +Q L T+ V T +K+I + V ++ FE
Sbjct: 5289 LEIEEIERSERDEK-EFEELVSFIQQRLSQTEPV-TLIKDIENQTVLKDNDAVFEIDIKI 5346
Query: 1549 N-PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
N P ++ WYK + + ++F I +R T +K +G Y G +
Sbjct: 5347 NYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIAS 5402
Query: 1608 AKLQVFQ 1614
AKL V +
Sbjct: 5403 AKLTVIE 5409
Score = 34.3 bits (75), Expect = 4.3
Identities = 81/377 (21%), Positives = 146/377 (38%), Gaps = 42/377 (11%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKP 207
K +E K+ PK + EK+ +L ++ +L VE E + S E P
Sbjct: 6868 KKEEAPPAKVPEVPKKVEEKRIILP----KEEEVLPVEVTEEPEEEPISE--EEIPEEPP 6921
Query: 208 RLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESK 267
+EE +EEV P P+ E++K E K ++ A K +
Sbjct: 6922 SIEE-VEEVAP--------------PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 6966
Query: 268 QKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNERQITEK 327
+K+P + + P KV + P K+ E L P +K+++ K + L+ + + +
Sbjct: 6967 EKVPVPVQKKEAPPAKVPEVP--KKVPEKKVLVP-KKEAVPPAKGRTV--LEEKVSVAFR 7021
Query: 328 KESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXX 387
+E + + +L+ +E I EE + + E + E +K +
Sbjct: 7022 QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVE 7081
Query: 388 XXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDIT 447
+ V E++E E + K P P E K+ P K T + K
Sbjct: 7082 KVHRVIEVF----EAEEVE--VFEKPKAPPKGPEISE--KIIPPKKPPTKVVPRKEPPAK 7133
Query: 448 LKPTRKQSLVDE---ITEEVCALKSALDDI-EKEEHKPDK---VSENNAPEERKWPTGKR 500
+ K+ +V+E + EE + + ++ +E P+K V PE P
Sbjct: 7134 VPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPP-PKVPE 7192
Query: 501 QPKEETPQEEVVLKPTR 517
PKE P+++V + P +
Sbjct: 7193 APKEVVPEKKVPVPPPK 7209
Score = 33.9 bits (74), Expect = 5.7
Identities = 83/383 (21%), Positives = 144/383 (37%), Gaps = 23/383 (6%)
Query: 139 ERGVIEEHVKVQEVVETKLWR-KPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSS 197
E V++ K +E K+ + + + E+K ++ E I +V +E T
Sbjct: 6339 EEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLE 6398
Query: 198 KLETKSWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQST 257
+ R+ EE E EP + + + E ++ EE +E +
Sbjct: 6399 EEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEH---EEYITEPE 6455
Query: 258 KALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDS-LMDEKSSEIS 316
K + VK ++ +P +A P KV K + +EK+ K ++ + E+ ++
Sbjct: 6456 KPIPVKPVPEEPVPTKPKA---PPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVF 6512
Query: 317 ELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTV 376
E + IT K+E Q T+ P K + V E K ++ + EV K +
Sbjct: 6513 EEKIHISIT-KREKEQVTE--PAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVP-KEL 6568
Query: 377 RXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKT 436
+ ++ E+E E+ T++ P IP + +P EK
Sbjct: 6569 EPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK 6628
Query: 437 PIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSE---NNAPEER 493
P+ K ++ P K V + EE K + +KE+ P KV E PEE+
Sbjct: 6629 PVPVPKKKE---APPAKVPEVPKKPEE----KVPVLIPKKEKPPPAKVPEVPKKPVPEEK 6681
Query: 494 -KWPTGKRQPKEETPQEEVVLKP 515
P K+ EV KP
Sbjct: 6682 VPVPVPKKVEAPPAKVPEVPKKP 6704
>AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform
protein.
Length = 1294
Score = 89.0 bits (211), Expect = 1e-16
Identities = 64/213 (30%), Positives = 99/213 (46%), Gaps = 15/213 (7%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P VL L+ TV G+ I GRP PKI W+ E+L+ T
Sbjct: 793 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 852
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I EAFPE A +Y C A N +G +T L++E VP V D ++ +
Sbjct: 853 LLI-EAFPEDAAVYTCEAKNDYGVATTSASLSVE----VPEVVSPD-------QEMPVYP 900
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P I+ L V T+EG+ R + + G +V W + ++ S +++ + +D T L
Sbjct: 901 PAIITPLQDTV-TSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQL 957
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
+ E Y +D G F A N +G ++ A LS+E
Sbjct: 958 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 990
Score = 68.9 bits (161), Expect = 2e-10
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDA------PLVLAPLENTTVMDGERISLNCK 1304
V TC A+N G +TS S VE + D P ++ PL++T +G+ C+
Sbjct: 864 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCR 923
Query: 1305 ILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
+ G K+ W+ +K I+ +R ++ Q ++ I EA+PE G Y ASN G+
Sbjct: 924 VSGTDL-KVSWYSKDKKIKPSRFFRMT-QFEDTYQLEIAEAYPEDEGTYTFVASNAVGQV 981
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEE 1397
S+ L++E S +DV K+ V +
Sbjct: 982 SSTANLSLEVQALDRQSSGKDVRESTKSQAVAD 1014
Score = 62.9 bits (146), Expect = 1e-08
Identities = 59/214 (27%), Positives = 94/214 (43%), Gaps = 20/214 (9%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI- 1458
P++++ L V T GK R A G P+P++ W ++ E L ST ++ + L DG
Sbjct: 795 PQVLQELQPV-TVQSGKPARFCAVISGRPQPKISWYKE--EQLLSTGFKCKFLHDGQEYT 851
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E + +D EA N GV T A+LSVE PE V+ +E+
Sbjct: 852 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV---------PEVVSPDQEMPVY--- 899
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P + + E + F+ SG ++ WY +K I+ F + E+
Sbjct: 900 ---PPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTY 955
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A + EGTYT A + +G + A L +
Sbjct: 956 QLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 989
Score = 56.8 bits (131), Expect = 7e-07
Identities = 48/213 (22%), Positives = 86/213 (40%), Gaps = 7/213 (3%)
Query: 1279 GDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLC 1338
G+AP + L++ TV G+ C + + + W H IE + + S Q +
Sbjct: 1088 GEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQS-QNGNIQ 1146
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
+ I G+Y C N G+ +T +L++E S+ E + E+ ++E
Sbjct: 1147 FLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAP--ESILHERI---EQEIEMEMK 1201
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
A ++K + G L + + P + +W + G E+ +S + I S
Sbjct: 1202 AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS-SKYISS 1260
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
L + D GE +A N G + A L+V
Sbjct: 1261 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1293
Score = 45.6 bits (103), Expect = 0.002
Identities = 42/181 (23%), Positives = 68/181 (37%), Gaps = 9/181 (4%)
Query: 1432 VRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
V W +G ++ +S + + + LT+ V D G +N G T A LSV
Sbjct: 1122 VTWTHEGAKIEESERLK-QSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV 1180
Query: 1492 ESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPT 1551
E PE + H Q ++ P ++I P V + F P
Sbjct: 1181 EGA--------PESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPN 1232
Query: 1552 PEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQ 1611
W+K + I ++ I + + ++ I + G YTCKA ++ G A L
Sbjct: 1233 VRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLT 1292
Query: 1612 V 1612
V
Sbjct: 1293 V 1293
>AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific titin
protein.
Length = 926
Score = 83.0 bits (196), Expect = 9e-15
Identities = 68/244 (27%), Positives = 107/244 (43%), Gaps = 18/244 (7%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E + +SE V + S+ E P +K + + G + L IGIPKP+++W
Sbjct: 25 ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNA-DISMGDVATLSVTVIGIPKPKIQWF 83
Query: 1436 RQGTELLQSTEYQ-IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
G L S +Y+ + + DD + I+ ++ +D GE A N G T A L + S
Sbjct: 84 FNGVLLTPSADYKFVFDGDDHSLIILFTKL--EDEGEYTCMASNDYGKTICSAYLKINS- 140
Query: 1495 VGTQEYRKPEWVTHMEELQAALKATQSV-----PTFVKEIIPERVHEEEIVTFEAIYSGN 1549
K E E A K+ + + P F+KE+ P R + FE G
Sbjct: 141 -------KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 193
Query: 1550 PTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P P + W+K+NK + T + II N T + ++ G Y CKA + +G + A
Sbjct: 194 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 253
Query: 1609 KLQV 1612
+L V
Sbjct: 254 ELLV 257
Score = 72.9 bits (171), Expect = 1e-11
Identities = 56/217 (25%), Positives = 92/217 (42%), Gaps = 7/217 (3%)
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+G P+ + + N + G+ +L+ ++G P PKI WF N L+ + D
Sbjct: 45 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 104
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGK--CSTECILNIEAYEYVPSVSEEDVLSD-EKTSD 1394
I + E G Y C ASN +GK CS +N + + + +E V EK
Sbjct: 105 SLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 163
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
P +K L + +G E +G P P V W ++ +L S Y I +
Sbjct: 164 --PCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 220
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
G+ + + ++D+G + +A N LG + A L V
Sbjct: 221 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 257
Score = 54.8 bits (126), Expect = 3e-06
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 1553 EILWYKDNKVIRTDERFIIENKENRTTCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQ 1611
E+ WY +NK++ +DE+F +N T I K T+D +G Y C+A++D G T AKL
Sbjct: 863 EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 922
Query: 1612 VFQR 1615
V +R
Sbjct: 923 VVKR 926
Score = 37.1 bits (82), Expect = 0.61
Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I D P++ PL +T +G+ + L I +++W+ KL+ + + ++
Sbjct: 830 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA--KEVNWYFENKLVPSDEKFKCLQDQNT 887
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ K + G Y C A N GK +T L +
Sbjct: 888 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 923
>AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.
Length = 1019
Score = 83.0 bits (196), Expect = 9e-15
Identities = 68/244 (27%), Positives = 107/244 (43%), Gaps = 18/244 (7%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
E + +SE V + S+ E P +K + + G + L IGIPKP+++W
Sbjct: 25 ETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNA-DISMGDVATLSVTVIGIPKPKIQWF 83
Query: 1436 RQGTELLQSTEYQ-IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
G L S +Y+ + + DD + I+ ++ +D GE A N G T A L + S
Sbjct: 84 FNGVLLTPSADYKFVFDGDDHSLIILFTKL--EDEGEYTCMASNDYGKTICSAYLKINS- 140
Query: 1495 VGTQEYRKPEWVTHMEELQAALKATQSV-----PTFVKEIIPERVHEEEIVTFEAIYSGN 1549
K E E A K+ + + P F+KE+ P R + FE G
Sbjct: 141 -------KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 193
Query: 1550 PTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
P P + W+K+NK + T + II N T + ++ G Y CKA + +G + A
Sbjct: 194 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 253
Query: 1609 KLQV 1612
+L V
Sbjct: 254 ELLV 257
Score = 72.9 bits (171), Expect = 1e-11
Identities = 56/217 (25%), Positives = 92/217 (42%), Gaps = 7/217 (3%)
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
+G P+ + + N + G+ +L+ ++G P PKI WF N L+ + D
Sbjct: 45 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 104
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGK--CSTECILNIEAYEYVPSVSEEDVLSD-EKTSD 1394
I + E G Y C ASN +GK CS +N + + + +E V EK
Sbjct: 105 SLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 163
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
P +K L + +G E +G P P V W ++ +L S Y I +
Sbjct: 164 --PCPPHFLKELKPI-RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 220
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
G+ + + ++D+G + +A N LG + A L V
Sbjct: 221 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 257
Score = 54.8 bits (126), Expect = 3e-06
Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 1553 EILWYKDNKVIRTDERFIIENKENRTTCTIKKA-TKDLEGTYTCKAVSDIGLAVTKAKLQ 1611
E+ WY +NK++ +DE+F +N T I K T+D +G Y C+A++D G T AKL
Sbjct: 863 EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 922
Query: 1612 VFQR 1615
V +R
Sbjct: 923 VVKR 926
Score = 44.0 bits (99), Expect = 0.005
Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 6/134 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
V+++ ++D G C A N +G +TS V ++ AP++ +E V G
Sbjct: 891 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRA-----APVIKRKIEPLEVALGHL 945
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
C+I P + WF + I + +I R + + I G Y C AS
Sbjct: 946 AKFTCEIQSAPNVRFQWFKAGREIYESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKAS 1004
Query: 1359 NQFGKCSTECILNI 1372
N++G S L +
Sbjct: 1005 NEYGSVSCTATLTV 1018
Score = 40.7 bits (91), Expect = 0.050
Identities = 45/215 (20%), Positives = 80/215 (37%), Gaps = 26/215 (12%)
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I D P++ PL +T +G+ + L I +++W+ KL+ + + ++
Sbjct: 830 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNA--KEVNWYFENKLVPSDEKFKCLQDQNT 887
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ K + G Y C A N GK +T L + V+
Sbjct: 888 YTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV----------------------VK 925
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
AP ++K + G L + + P + +W + G E+ +S + I
Sbjct: 926 RAAP-VIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS-SKYI 983
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
S L + D GE +A N G + A L+V
Sbjct: 984 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1018
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 78.6 bits (185), Expect = 2e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 1374
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1375 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 76.6 bits (180), Expect = 8e-13
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 36/275 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG + + + I G L TV++G ISL C+ G P
Sbjct: 2170 GRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGIP 2224
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE-- 2281
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2282 YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T L
Sbjct: 2322 PTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 1490 SVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
SV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 SVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2411
Score = 67.3 bits (157), Expect = 5e-10
Identities = 74/249 (29%), Positives = 105/249 (42%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2926 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2976
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W NE+ I+ + I G + I A G Y
Sbjct: 2977 VVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3033
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A NQ G+ + L + YV PS+ + D E S VV
Sbjct: 3034 TCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3071
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3128
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3129 VCRAINVAG 3137
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 64.9 bits (151), Expect = 3e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3018 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3071
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3072 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3129 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3164
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3165 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3223
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3224 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3263
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3264 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3318 TCVATNPAG 3326
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3178
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3238 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3274
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3275 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 1489 LSV 1491
L+V
Sbjct: 3334 LNV 3336
Score = 59.7 bits (138), Expect = 1e-07
Identities = 63/240 (26%), Positives = 95/240 (39%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V G V+E GD P N G L
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4369
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4370 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4425
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4426 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4460
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4461 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4516
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 1348 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 1387 TPSPIIMWYKDNVQVTESS--TIQTVNNG-KILKLFRATPEDAGRYSCKAINIAGTSQKY 1443
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 1444 FNIDVLVPPTIIGT 1457
Score = 53.2 bits (122), Expect = 9e-06
Identities = 63/252 (25%), Positives = 103/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4279
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S+ + G I L
Sbjct: 4335 G--------FVKAIGFV-YVKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4370
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4426
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4427 VVERSMSLTLQS 4438
Score = 51.2 bits (117), Expect = 4e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3193 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3251 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3303
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3348
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 3349 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 3391
Score = 49.2 bits (112), Expect = 1e-04
Identities = 75/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 48.8 bits (111), Expect = 2e-04
Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S +L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3390 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3442
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3499
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3500 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3545
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3546 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3593
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3649
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3872 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3915
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3916 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3952
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3953 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4000
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4001 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4052
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4053 AGTYMCVAQNPAGTALGKIKLNV 4075
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4196
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4197 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4253
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4254 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 4343
Query: 1490 SVE 1492
V+
Sbjct: 4344 YVK 4346
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 44.8 bits (101), Expect = 0.003
Identities = 81/366 (22%), Positives = 129/366 (35%), Gaps = 63/366 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ S V I G +V + N + L C+ G P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNP-------VRLECEARGIP 2039
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W + + + + + SG + + A G Y C A N G+ +
Sbjct: 2040 APSLTWLKDGSPVSSFSNGL--QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDID 2097
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + YVP +++ +E+ V+ + + L ++ IP
Sbjct: 2098 LRV----YVPP----NIMGEEQN-----------------VSVLISQAVELLCQSDAIPP 2132
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G LL+ I E S+L + + DTG EA N G T
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISE---NRSVLKIEDAQVQDTGRYTCEATNVAGKT------ 2183
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ Y WV + + + TQ V E +++ SG
Sbjct: 2184 -------EKNYNVNIWVP--PNIGGSDELTQLT-----------VIEGNLISLLCESSGI 2223
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P ++W K + TD + I A K Y+C A + G A +
Sbjct: 2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN 2283
Query: 1610 LQVFQR 1615
LQV+ R
Sbjct: 2284 LQVYIR 2289
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3743
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3744 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3790
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3791 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3835
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3836 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3893
Query: 1492 E 1492
+
Sbjct: 3894 Q 3894
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2542
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2585
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2586 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2639
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2640 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2691
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2692 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2737
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2738 SDTGRYTCVASNIAG 2752
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2547
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2548 YTCLASSPAGHKSRSFSLNVF 2568
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3502 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3556
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3557 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3612
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3613 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3649
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3650 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Query: 1489 LSV 1491
L+V
Sbjct: 3707 LTV 3709
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4015
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4016 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4072
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4073 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4107
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4108 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Query: 1490 SV 1491
+V
Sbjct: 4164 TV 4165
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4443
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4444 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4498
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4499 AQKEDTSEFECVARNLMG 4516
Score = 42.3 bits (95), Expect = 0.016
Identities = 67/269 (24%), Positives = 98/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2406
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P I WF + + + + I SG + + + E AG Y C N
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2463
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2464 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2502
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2503 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2558 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2586
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3687
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3722
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3723 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3779
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3780 RYLCMATNAAG 3790
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4078 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4134
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4135 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4168
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4169 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4223
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4283
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4284 T-GIPLPKLTWTFNNNIIP 4301
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2623 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2681 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2736
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2737 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2787
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2788 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2840
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2841 EDAGRYTCVAVNEAG 2855
Score = 36.3 bits (80), Expect = 1.1
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2785 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2841
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + + SD LP
Sbjct: 2842 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIKG------ANSD-----------LPE 2880
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2881 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2937
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 1452 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 1510
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 3046
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3047 KFSLTVY 3053
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4071 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4131 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4165
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 3158 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 3216 HSDSGNYTCIASNMEGKA 3233
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens cDNA
FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 77.8 bits (183), Expect = 4e-13
Identities = 98/370 (26%), Positives = 148/370 (40%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 202 PSGSMKITETRTSDS--GMYLCVAINIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 252
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 253 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 309
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 310 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 351
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L+DGT +L + V D GE
Sbjct: 352 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGT-LLVIASVTPYDNGEY 407
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + +K + V T V ++
Sbjct: 408 ICVAVNE---------------AGTTE-RKYNLKVHVPPV---IKDKEQV-TNVSVLL-- 445
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
++ G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 446 ----NQLTNLFCEVEGTPSPIIMWYKDN--VQVTESSTIQTVNNGRILKLFRATPEDAGR 499
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 500 YSCKAINIAG 509
Score = 66.1 bits (154), Expect = 1e-09
Identities = 92/353 (26%), Positives = 138/353 (39%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 965 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1019
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + +L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1020 VPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 1074
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 1075 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 1111
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 1112 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSAQISDTGRYTCVAVN--------AAG 1161
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 1162 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 1201
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 1202 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 58.4 bits (135), Expect = 2e-07
Identities = 85/365 (23%), Positives = 140/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P +V+ ++L C++ G
Sbjct: 498 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------NEVSVVLNRDVALECQVKGT 551
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 552 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 609
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE + G+
Sbjct: 610 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECETRGL 645
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 646 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 696
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 697 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECKAA 737
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ IE + I A + G Y C A S G K
Sbjct: 738 GNPSPILTWLKDGVPVKANDNIRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 795
Query: 1608 AKLQV 1612
++ V
Sbjct: 796 YEVDV 800
Score = 56.8 bits (131), Expect = 7e-07
Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 39/254 (15%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 308 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 362
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 363 GTPKPTIKWLHNGREL-TGREPGISILEDGTLLV-IASVTPYDNGEYICVAVNEAG--TT 418
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ +VP V ++ K T V+ +L L + G
Sbjct: 419 ERKYNLKV--HVPPVIKD-------------------KEQVTNVSVLLNQLTNLFCEVEG 457
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA-- 1484
P P + W + ++ +S+ I+ +++G IL + +D G +A N G +
Sbjct: 458 TPSPIIMWYKDNVQVTESS--TIQTVNNG-RILKLFRATPEDAGRYSCKAINIAGTSQKY 514
Query: 1485 -TIAALSVESIVGT 1497
I L +I+GT
Sbjct: 515 FNIDVLVPPTIIGT 528
Score = 50.8 bits (116), Expect = 5e-05
Identities = 84/363 (23%), Positives = 138/363 (38%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 27 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 79
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 80 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 136
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V ++ LS +K P ++ G+ + L + +P
Sbjct: 137 LTVYVRPRV--FGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 179
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 180 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVAINIAG- 228
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 229 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 268
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 269 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 326
Query: 1610 LQV 1612
L V
Sbjct: 327 LHV 329
Score = 48.8 bits (111), Expect = 2e-04
Identities = 74/320 (23%), Positives = 117/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +L++ I L I +A G+
Sbjct: 817 VMVNNLLELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKLV---IAQAQVSNTGL 873
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 874 YRCMAANTAGDHKEE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 914
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 915 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 967
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 968 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1001
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN+++ N+ I+ A G
Sbjct: 1002 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1059
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1060 YKCVAINSAGATELFYSLQV 1079
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 878 AANTAGDHKEEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 937
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 938 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 992
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 993 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNRLL 1032
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1033 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 1079
Score = 38.7 bits (86), Expect = 0.20
Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 1508 HMEELQAALKATQSVPTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTD 1566
H EE + + PT + ERV + + V + I +G P P I W KD++ + T
Sbjct: 885 HKEEFEVTVHVP---PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTA 941
Query: 1567 ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
+ + R K +D G YTC A + G +L V +
Sbjct: 942 QGNLKIQSSGRVLQIAKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 988
Score = 37.1 bits (82), Expect = 0.61
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 2/76 (2%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
VT SGNP P ++W K ++I T + + + + G Y C A +
Sbjct: 69 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG--SLYVVSPGGEESGEYVCTATN 126
Query: 1600 DIGLAVTKAKLQVFQR 1615
G A K +L V+ R
Sbjct: 127 TAGYAKRKVQLTVYVR 142
Score = 34.7 bits (76), Expect = 3.3
Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHE--EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
PT + P V V E G P P+I W+KD K + + +E +
Sbjct: 523 PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVL 581
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+K A ++ +G Y C + G KL ++
Sbjct: 582 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 614
>BC111395-1|AAI11396.1| 554|Homo sapiens NEXN protein protein.
Length = 554
Score = 77.0 bits (181), Expect = 6e-13
Identities = 40/121 (33%), Positives = 61/121 (50%), Gaps = 3/121 (2%)
Query: 1257 ENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF 1316
E GS+ ++ EEQT AP PL+NT+V+D E + K+ G P P+I W+
Sbjct: 437 EEEEGSIMNGSTAEDEEQT--RSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWW 494
Query: 1317 HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
++++ D + C +++ E FPE G Y C A N G ++ CIL IE +
Sbjct: 495 FEGEILQDGEDYQYIERGETYC-LYLPETFPEDGGEYMCKAVNNKGSAASTCILTIETDD 553
Query: 1377 Y 1377
Y
Sbjct: 554 Y 554
Score = 52.8 bits (121), Expect = 1e-05
Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 1383 EEDVLSDEKTSDVEEF----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
EE + + T++ EE AP K L + + + +R K G PKP++ W +G
Sbjct: 439 EEGSIMNGSTAEDEEQTRSGAPWFKKPLKNT-SVVDSEPVRFTVKVTGEPKPEITWWFEG 497
Query: 1439 TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L +YQ E + T L +PE + +D GE + +A N+ G A+ L++E+
Sbjct: 498 EILQDGEDYQYIERGE-TYCLYLPETFPEDGGEYMCKAVNNKGSAASTCILTIET 551
Score = 41.5 bits (93), Expect = 0.029
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF-IIENKENRTTCT 1581
P F K + V + E V F +G P PEI W+ + ++++ E + IE E T C
Sbjct: 460 PWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWWFEGEILQDGEDYQYIERGE--TYCL 517
Query: 1582 -IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + + G Y CKAV++ G A + L +
Sbjct: 518 YLPETFPEDGGEYMCKAVNNKGSAASTCILTI 549
>AF114264-1|AAD29607.1| 448|Homo sapiens unknown protein.
Length = 448
Score = 77.0 bits (181), Expect = 6e-13
Identities = 40/121 (33%), Positives = 61/121 (50%), Gaps = 3/121 (2%)
Query: 1257 ENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF 1316
E GS+ ++ EEQT AP PL+NT+V+D E + K+ G P P+I W+
Sbjct: 331 EEEEGSIMNGSTAEDEEQT--RSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWW 388
Query: 1317 HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
++++ D + C +++ E FPE G Y C A N G ++ CIL IE +
Sbjct: 389 FEGEILQDGEDYQYIERGETYC-LYLPETFPEDGGEYMCKAVNNKGSAASTCILTIETDD 447
Query: 1377 Y 1377
Y
Sbjct: 448 Y 448
Score = 52.8 bits (121), Expect = 1e-05
Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 1383 EEDVLSDEKTSDVEEF----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
EE + + T++ EE AP K L + + + +R K G PKP++ W +G
Sbjct: 333 EEGSIMNGSTAEDEEQTRSGAPWFKKPLKNT-SVVDSEPVRFTVKVTGEPKPEITWWFEG 391
Query: 1439 TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L +YQ E + T L +PE + +D GE + +A N+ G A+ L++E+
Sbjct: 392 EILQDGEDYQYIERGE-TYCLYLPETFPEDGGEYMCKAVNNKGSAASTCILTIET 445
Score = 41.5 bits (93), Expect = 0.029
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF-IIENKENRTTCT 1581
P F K + V + E V F +G P PEI W+ + ++++ E + IE E T C
Sbjct: 354 PWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWWFEGEILQDGEDYQYIERGE--TYCL 411
Query: 1582 -IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + + G Y CKAV++ G A + L +
Sbjct: 412 YLPETFPEDGGEYMCKAVNNKGSAASTCILTI 443
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 75.8 bits (178), Expect = 1e-12
Identities = 95/370 (25%), Positives = 145/370 (39%), Gaps = 62/370 (16%)
Query: 1233 PLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT 1292
P ++ + E S G+ C A N AG+V+ + V P + ++
Sbjct: 1131 PSGSMKITETRTSDS--GMYLCVATNIAGNVTQAVKLNVHVP-------PKIQRGPKHLK 1181
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
V G+R+ + C G P P I W + + +S L I +A P AGI
Sbjct: 1182 VQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS---IDQATPSDAGI 1238
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y C A+N G TE L+++ P+V ED+ T+ E A
Sbjct: 1239 YTCVATNIAGTDETEITLHVQE---PPTV--EDLEPPYNTTFQERVA------------- 1280
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ I A G PKP ++WL G EL E I L++GT +L + V D GE
Sbjct: 1281 --NQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEEGT-LLVIASVTPYDNGEY 1336
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
+ A N GT E RK H+ + + +V + ++
Sbjct: 1337 ICVAVNE---------------AGTTE-RKYNLKVHVPPVIKDKEQVSNVSVLLNQLTNL 1380
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
E G P+P I+WYKDN ++ E I+ N + +AT + G
Sbjct: 1381 FCEVE----------GTPSPIIMWYKDN--VQVTESSTIQTVNNGKILKLFRATPEDAGR 1428
Query: 1593 YTCKAVSDIG 1602
Y+CKA++ G
Sbjct: 1429 YSCKAINIAG 1438
Score = 75.4 bits (177), Expect = 2e-12
Identities = 80/276 (28%), Positives = 118/276 (42%), Gaps = 37/276 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSI-VEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G TC A N AG ++ + I G L TV++G ISL C+ G
Sbjct: 2170 GRYTCEATNVAGKTEKKNYNVNIWVPPNIGGSDELT-----QLTVIEGNLISLLCESSGI 2224
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P + W + T + R SG ++ I A A +Y C ASN G E
Sbjct: 2225 PPPNLIWKKKGSPVLTDSMGRV-RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKE- 2282
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
N++ Y P+++ + PT + T GK I LE + GIP
Sbjct: 2283 -YNLQVY-IRPTITNSG-------------------SHPTEIIVTRGKSISLECEVQGIP 2321
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P V W++ G L+++ +E LD+G IL + ++ DTG V A N G+T
Sbjct: 2322 PPTVTWMKDGHPLIKAK--GVEILDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYD 2378
Query: 1489 LSVE---SIVGTQEYRKPEWVTHMEELQAALKATQS 1521
LSV SI+G +R PE ++ +E+ +L S
Sbjct: 2379 LSVHAPPSIIG--NHRSPENISVVEKNSVSLTCEAS 2412
Score = 65.3 bits (152), Expect = 2e-09
Identities = 98/369 (26%), Positives = 134/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 3019 RTLQIIRAKVSDG--GEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 3072
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL C+ P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 3073 REGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 3129
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 3130 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 3165
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 3166 ISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 3224
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 3225 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 3264
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 3265 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3318
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 3319 TCVATNPAG 3327
Score = 64.1 bits (149), Expect = 5e-09
Identities = 92/353 (26%), Positives = 137/353 (38%), Gaps = 65/353 (18%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG V E ++ DA +L N TV+ + L CK G P
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLE-DAGKML----NETVLVSNPVQLECKAAGNP 1948
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W+ + L+ + +T + I I+ A AGIYKC A N G +TE
Sbjct: 1949 VPVITWYKDNCLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAG--ATELF 2003
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
+++ + PS+S + +V +RLE +A GIP
Sbjct: 2004 YSLQVH-VAPSISGSN----------------------NMVAVVVNNPVRLECEARGIPA 2040
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + WL+ G+ + S ++ L G IL + DTG A N AA
Sbjct: 2041 PSLTWLKDGSP-VSSFSNGLQVLSGG-RILALTSTQISDTGRYTCVAVN--------AAG 2090
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+ + + Y P + EE ++ +Q+V E + +AI
Sbjct: 2091 EKQRDIDLRVYVPPNIMG--EEQNVSVLISQAV--------------ELLCQSDAI---- 2130
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
P P + W KD + I ENR+ I+ A G YTC+A + G
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 62.9 bits (146), Expect = 1e-08
Identities = 87/365 (23%), Positives = 142/365 (38%), Gaps = 64/365 (17%)
Query: 1250 GVVTCRAENFAG-SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
G +C+A N AG S ++ T I + P + +V+ ++L C++ G
Sbjct: 1427 GRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFP------KEVSVVLNRDVALECQVKGT 1480
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+P I WF + K + D + G +H+K A G Y+CT SN GK + +
Sbjct: 1481 PFPDIHWFKDGKPLFLG-DPNVELLDRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 1369 ILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
L I Y+ PS+ +V +D ++ LI+LE K G+
Sbjct: 1539 KLTI----YIPPSIKGGNVTTD--------------------ISVLINSLIKLECKTRGL 1574
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P + W + G ++ S+ Q +D G L +P D+ N G
Sbjct: 1575 PMPAITWYKDGQPIMSSS--QALYIDKG-QYLHIPRAQVSDSATYTCHVANVAG------ 1625
Query: 1488 ALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYS 1547
+ E Y P ++ + P + +I H +T E +
Sbjct: 1626 --TAEKSFHVDVYVPP-----------MIEGNLATPLNKQVVI---AHS---LTLECNAA 1666
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
GNP+P + W KD ++ ++ F IE + I A + G Y C A S G K
Sbjct: 1667 GNPSPILTWLKDGVPVKANDNFRIEAGGKK--LEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 1608 AKLQV 1612
++ V
Sbjct: 1725 YEVDV 1729
Score = 62.5 bits (145), Expect = 1e-08
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S +L V A + VS+ G S + P V +N + G +S+
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P PKI W N+ I + ++ + + IK A P+ AGIY C ASN G
Sbjct: 633 CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT----LFIKNAAPKDAGIYGCLASNSAG 688
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPTVVTTTEGKLIRLE 1421
+D++ S + AP+++ + + + G + +E
Sbjct: 689 -------------------------TDKQNSTLRYIEAPKLM-VVQSELLVALGDITVME 722
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
K GIP PQV+W + EL ST I+ L +L + E D G+ A N G
Sbjct: 723 CKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGLLKIQETQDLDAGDYTCVAINEAG 779
Query: 1482 VTATIAALSVES 1493
L V S
Sbjct: 780 RATGKITLDVGS 791
Score = 62.5 bits (145), Expect = 1e-08
Identities = 72/249 (28%), Positives = 103/249 (41%), Gaps = 39/249 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-ENTTV 1293
+ L +L I+ IG C AEN AGS + V P V+ P EN TV
Sbjct: 2927 RILQILNTQITD--IGRYVCVAENTAGSAKKYFNLNVHVP-------PSVIGPKSENLTV 2977
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+ ISL C++ G P P + W N + I+ + I G + I A G Y
Sbjct: 2978 VVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLI---VPGGRTLQIIRAKVSDGGEY 3034
Query: 1354 KCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
C A N G+ + L + YV PS+ + D E S VV
Sbjct: 3035 TCIAINXAGESKKKFSLTV----YVPPSIKDHD---SESLS---------------VVNV 3072
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + LE ++ +P P + W + G + +ST +E L DG +L + + DTG+
Sbjct: 3073 REGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADG-QMLHIKKAEVSDTGQY 3129
Query: 1473 VFEAYNHLG 1481
V A N G
Sbjct: 3130 VCRAINVAG 3138
Score = 61.7 bits (143), Expect = 2e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 737 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 789
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 790 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 848
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 885
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 943
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 944 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 989
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 990 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 1033
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 1034 G--SLYVVSPEGEESGEYVCTATNTAGYAKRKVQLTVYVR 1071
Score = 60.9 bits (141), Expect = 4e-08
Identities = 63/240 (26%), Positives = 96/240 (40%), Gaps = 39/240 (16%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
E +SK+ G C AEN G V +G V+E GD P N G L
Sbjct: 4317 ERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPVFKGDYP------SNWIEPLGGNAIL 4370
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
NC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 4371 NCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEA 4426
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G L ++ +P I+ P G I L
Sbjct: 4427 GVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIILN 4461
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +G
Sbjct: 4462 CQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLMG 4517
Score = 60.1 bits (139), Expect = 8e-08
Identities = 89/367 (24%), Positives = 143/367 (38%), Gaps = 63/367 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD---GERISLNCKIL 1306
G+ TC A N AG+ T + V+E ++ L P NTT + +RI C
Sbjct: 1237 GIYTCVATNIAGTDETEITLHVQEPPTVED-----LEPPYNTTFQERVANQRIEFPCPAK 1291
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
G P P I W HN + + T R+ IS + G + I P G Y C A N+ G +T
Sbjct: 1292 GTPKPTIKWLHNGREL-TGREPGISILEEGTLLV-IASVTPYDNGEYICVAVNEAG--TT 1347
Query: 1367 ECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
E N++ + VP V ++ E+ S+V +L L + G
Sbjct: 1348 ERKYNLKVH--VPPVIKDK----EQVSNVSVLL---------------NQLTNLFCEVEG 1386
Query: 1427 IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATI 1486
P P + W + ++ +S+ I+ +++G IL + +D G +A N
Sbjct: 1387 TPSPIIMWYKDNVQVTESST--IQTVNNG-KILKLFRATPEDAGRYSCKAIN-------- 1435
Query: 1487 AALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIY 1546
I GT + + + T F KE+ V V E
Sbjct: 1436 -------IAGTSQ--------KYFNIDVLVPPTIIGTNFPKEV---SVVLNRDVALECQV 1477
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
G P P+I W+KD K + + +E + +K A ++ +G Y C + G
Sbjct: 1478 KGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAK 1536
Query: 1607 KAKLQVF 1613
KL ++
Sbjct: 1537 DIKLTIY 1543
Score = 59.3 bits (137), Expect = 1e-07
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 3127 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 3179
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 3180 PPPTIAWLKNYKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3238
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 3239 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 3275
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 3276 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 3334
Query: 1489 LSV 1491
L+V
Sbjct: 3335 LNV 3337
Score = 53.2 bits (122), Expect = 9e-06
Identities = 62/252 (24%), Positives = 101/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 4228 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 4280
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 4281 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 4335
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G + + Y V E V + S+ + G I L
Sbjct: 4336 G------FVKATGFVY---VKEPPVFKGDYPSN--------------WIEPLGGNAI-LN 4371
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 4372 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 4427
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 4428 VVERSMSLTLQS 4439
Score = 49.2 bits (112), Expect = 1e-04
Identities = 84/363 (23%), Positives = 137/363 (37%), Gaps = 60/363 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 956 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 1008
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 1009 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPEGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + V + LS +K P ++ G+ + L + +P
Sbjct: 1066 LTVYVRPRV--FGDLRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 1108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G +L V IA
Sbjct: 1109 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGM-------YLCVATNIAG- 1157
Query: 1490 SVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGN 1549
+V V + P+ Q P +K + +RV + A G
Sbjct: 1158 NVTQAVKLNVHVPPK--------------IQRGPKHLKVQVGQRVD----IPCNA--QGT 1197
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
P P I W K + D + N + T +I +AT G YTC A + G T+
Sbjct: 1198 PLPVITWSKGGSTMLVDGEHHVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEIT 1255
Query: 1610 LQV 1612
L V
Sbjct: 1256 LHV 1258
Score = 48.4 bits (110), Expect = 2e-04
Identities = 54/219 (24%), Positives = 84/219 (38%), Gaps = 31/219 (14%)
Query: 1240 LEENISKDL-IGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGE 1297
L+E+ S L I VT E F ++ S + QT D + P V+ N TV GE
Sbjct: 476 LKESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
R L C I+ + W N++ + A I R + L + +K AG Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI-RTLANL-SLELKSVKFNDAGEYHCMV 593
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
S++ G + L ++ P V +P + T G
Sbjct: 594 SSEGGSSAASVFLTVQ-------------------------EPPKVTVMPKNQSFTGGSE 628
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
+ + A G PKP++ W ++ S Y++ DGT
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM--TSDGT 665
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 3391 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 3443
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 3444 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 3500
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 3501 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 3546
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 3547 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 3594
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 3595 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 3650
Score = 47.6 bits (108), Expect = 4e-04
Identities = 57/230 (24%), Positives = 89/230 (38%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 3194 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3251
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 3252 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 3304
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 3305 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 3349
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T V T+ I +E + G P PQ+ WL+ G L S+ ++
Sbjct: 3350 ---AEKLMTYVDTS----INIECRXTGTPPPQINWLKNGLPLPLSSHIRL 3392
Score = 47.2 bits (107), Expect = 6e-04
Identities = 75/320 (23%), Positives = 116/320 (36%), Gaps = 57/320 (17%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
VM + L+C + G P P I W + +LI+ I L I +A G+
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLV---IAQAQVSNTGL 1802
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y+C A+N G E E +VP + LS+ +VK P
Sbjct: 1803 YRCMAANTAGDHKKE----FEVTVHVPPTIKSSGLSERV----------VVKYKP----- 1843
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+ L+ A GIP P + WL+ + +T ++ +L + + +D G
Sbjct: 1844 -----VALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A N G TQ++ + H+ E + A + ++ E
Sbjct: 1897 TCVATNAAGE--------------TQQHIQ----LHVHEPPSLEDAGK--------MLNE 1930
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
V V E +GNP P I WYKDN ++ N+ I+ A G
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQ--IIDIESAQISDAGI 1988
Query: 1593 YTCKAVSDIGLAVTKAKLQV 1612
Y C A++ G LQV
Sbjct: 1989 YKCVAINSAGATELFYSLQV 2008
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 3813 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3872
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 3873 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 3916
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 3917 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 3953
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 3954 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 4001
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 4002 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 4053
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 4054 AGTYMCVAQNPAGTALGKIKLNV 4076
Score = 45.6 bits (103), Expect = 0.002
Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 28/230 (12%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+ +T+G E + + + + L V+ + ++L C G P P I W +++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ TA+ + Q SG + I + E AG Y C A+N G+ T+ + + +E PS+
Sbjct: 1867 VNTAQG-NLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGE--TQQHIQLHVHE-PPSL 1921
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
+ + +E TV+ + ++LE KA G P P + W + L
Sbjct: 1922 EDAGKMLNE-----------------TVLVSNP---VQLECKAAGNPVPVITWYKDNCLL 1961
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
ST L+ G I+ + D G A N G T +L V
Sbjct: 1962 SGSTSMTF--LNRG-QIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 45.2 bits (102), Expect = 0.002
Identities = 61/237 (25%), Positives = 96/237 (40%), Gaps = 41/237 (17%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 4145 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 4197
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 4198 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 4254
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 4255 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 4289
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG-VTAT 1485
P++ W + + +G S L + V ++D+G V A N +G V AT
Sbjct: 4290 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAT 4341
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 3692 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 3744
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 3745 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 3791
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 3792 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 3836
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 3837 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 3894
Query: 1492 E 1492
+
Sbjct: 3895 Q 3895
Score = 43.6 bits (98), Expect = 0.007
Identities = 51/226 (22%), Positives = 82/226 (36%), Gaps = 28/226 (12%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
++ D+ + P + V+ + + L ++ IP P + WL+ G LL+ I
Sbjct: 2093 QRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSI 2152
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
E S+L + + DTG EA N G T + Y WV
Sbjct: 2153 SE---NRSVLKIEDAQVQDTGRYTCEATNVAGKTE------------KKNYNVNIWVP-- 2195
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF 1569
+ + + TQ V E +++ SG P P ++W K + TD
Sbjct: 2196 PNIGGSDELTQLT-----------VIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMG 2244
Query: 1570 IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ I A K Y+C A + G A + LQV+ R
Sbjct: 2245 RVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIR 2290
Score = 43.2 bits (97), Expect = 0.009
Identities = 69/315 (21%), Positives = 115/315 (36%), Gaps = 48/315 (15%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
LE+ V + + ++L C++ G P P+I W + + ++ I SG + I
Sbjct: 2487 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQV 2543
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
G Y C AS+ G S LN+ + V SD DV
Sbjct: 2544 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVG-----SDGNPEDV------------ 2586
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
TV+ + L+ +A P + W + GT L + +I L G + L + +D
Sbjct: 2587 TVILNSPTSLV---CEAYSYPPATITWFKDGTPLESNRNIRI--LPGGRT-LQILNAQED 2640
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVK 1527
+ G A N G I V+ + + W + + +K +
Sbjct: 2641 NAGRYSCVATNEAG--EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNT------ 2692
Query: 1528 EIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATK 1587
+T E P+ + WYKD + +++D+ + N T IK+A
Sbjct: 2693 ------------LTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANGHTLQIKEAQI 2738
Query: 1588 DLEGTYTCKAVSDIG 1602
G YTC A + G
Sbjct: 2739 SDTGRYTCVASNIAG 2753
Score = 43.2 bits (97), Expect = 0.009
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 1533 RVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGT 1592
+V E++ VT +GNP PEI W+KD + ++ DE I + I G
Sbjct: 2491 KVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGR 2548
Query: 1593 YTCKAVSDIGLAVTKAKLQVF 1613
YTC A S G L VF
Sbjct: 2549 YTCLASSPAGHKSRSFSLNVF 2569
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 3503 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 3557
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 3558 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 3613
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 3614 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 3650
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 3651 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 3707
Query: 1489 LSV 1491
L+V
Sbjct: 3708 LTV 3710
Score = 42.7 bits (96), Expect = 0.012
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 3964 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 4016
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 4017 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 4073
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 4074 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 4108
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ L + V D G A N G ++T L
Sbjct: 4109 PDITWHKDGRAIVESIRQRV--LSSGS--LQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4164
Query: 1490 SV 1491
+V
Sbjct: 4165 TV 4166
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 4392 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 4444
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 4445 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 4499
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 4500 AQKEDTSEFECVARNLMG 4517
Score = 40.3 bits (90), Expect = 0.066
Identities = 66/269 (24%), Positives = 97/269 (36%), Gaps = 36/269 (13%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
+NI G C A N AG V I G+ +P EN +V++ +SL
Sbjct: 2352 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHR---SP-ENISVVEKNSVSL 2407
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C+ G P P WF + + + + I SG + + + E AG Y C N
Sbjct: 2408 TCEASGIPLPSTTWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMEDAGQYTCVVRNAA 2464
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G+ I + P + E+ L D K VK +V T E
Sbjct: 2465 GE--ERKIFGLSVL-VPPHIVGENTLEDVK-----------VKEKQSVTLTCE------- 2503
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
G P P++ W + G L E + + G L + V TG A + G
Sbjct: 2504 --VTGNPVPEITWHKDGQPL---QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2558
Query: 1482 VTATIAALSV---ESIVGTQEYRKPEWVT 1507
+ +L+V +I G PE VT
Sbjct: 2559 HKSRSFSLNVFVSPTIAGVGSDGNPEDVT 2587
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 3633 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 3688
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 3689 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 3723
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 3724 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 3780
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 3781 RYLCMATNAAG 3791
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 4079 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 4135
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 4136 IAFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 4169
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 4170 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 4224
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 4225 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 4284
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 4285 T-GIPLPKLTWTFNNNIIP 4302
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 717 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 773
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 774 AINEAGRATGKITLDV 789
Score = 37.9 bits (84), Expect = 0.35
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 30/211 (14%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E V+ ISL C+ P P + W+ + + ++ + I G + I A E
Sbjct: 2786 EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKVE 2842
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ S L + VP + E SD LP
Sbjct: 2843 DAGRYTCVAVNEAGEDS----LQYDVRVLVPPIIEG------ANSD-----------LPE 2881
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
VT K +E + G P P+ W + G LL+ ++ L +G IL + D
Sbjct: 2882 EVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNG-RILQILNTQITD 2938
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVG 1496
G V A N G L+V S++G
Sbjct: 2939 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2969
Score = 37.5 bits (83), Expect = 0.47
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 1523 PTFVKEIIPERVHEE-EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
PT + ERV + + V + I +G P P I W KD++ + T + + R
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
K +D G YTC A + G +L V +
Sbjct: 1886 AKTLLED-AGRYTCVATNAAGETQQHIQLHVHE 1917
Score = 37.5 bits (83), Expect = 0.47
Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 24/255 (9%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDA-PLVLA 1286
RI+ + L +L N +D G +C A N AG + V I+ GD L+
Sbjct: 2624 RILPGGRTLQIL--NAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2681
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
P E + ++L C+ P + W+ + + +++ + I+ L IKEA
Sbjct: 2682 PKE-VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTL---QIKEAQ 2737
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
G Y C ASN G+ + +NI+ + E + D R +A
Sbjct: 2738 ISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLD---------TGRNGEAK 2788
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQ 1466
++ I L + P P + W + G L S + I G +L +P
Sbjct: 2789 DVIINNP----ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLIL---PGGRVLQIPRAKV 2841
Query: 1467 DDTGEIVFEAYNHLG 1481
+D G A N G
Sbjct: 2842 EDAGRYTCVAVNEAG 2856
Score = 34.7 bits (76), Expect = 3.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 4072 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4131
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 4132 GSLQIAFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 4166
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 2990 SGFPPPDLSWLKNXQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINXAGESKK 3047
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 3048 KFSLTVY 3054
>DQ464902-1|ABE97925.1| 675|Homo sapiens nexilin protein.
Length = 675
Score = 74.9 bits (176), Expect = 3e-12
Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 3/118 (2%)
Query: 1257 ENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF 1316
E GS+ ++ EEQT AP PL+NT+V+D E + K+ G P P+I W+
Sbjct: 559 EEEEGSIMNGSTAEDEEQT--RSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWW 616
Query: 1317 HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
++++ D + C +++ E FPE G Y C A N G ++ CIL IE+
Sbjct: 617 FEGEILQDGEDYQYIERGETYC-LYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 673
Score = 54.0 bits (124), Expect = 5e-06
Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 1383 EEDVLSDEKTSDVEEF----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
EE + + T++ EE AP K L + + + +R K G PKP++ W +G
Sbjct: 561 EEGSIMNGSTAEDEEQTRSGAPWFKKPLKNT-SVVDSEPVRFTVKVTGEPKPEITWWFEG 619
Query: 1439 TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L +YQ E + T L +PE + +D GE + +A N+ G A+ L++ES
Sbjct: 620 EILQDGEDYQYIERGE-TYCLYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 673
Score = 41.5 bits (93), Expect = 0.029
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF-IIENKENRTTCT 1581
P F K + V + E V F +G P PEI W+ + ++++ E + IE E T C
Sbjct: 582 PWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWWFEGEILQDGEDYQYIERGE--TYCL 639
Query: 1582 -IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + + G Y CKAV++ G A + L +
Sbjct: 640 YLPETFPEDGGEYMCKAVNNKGSAASTCILTI 671
>BC114445-1|AAI14446.1| 567|Homo sapiens NEXN protein protein.
Length = 567
Score = 74.9 bits (176), Expect = 3e-12
Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 3/118 (2%)
Query: 1257 ENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF 1316
E GS+ ++ EEQT AP PL+NT+V+D E + K+ G P P+I W+
Sbjct: 451 EEEEGSIMNGSTAEDEEQT--RSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWW 508
Query: 1317 HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
++++ D + C +++ E FPE G Y C A N G ++ CIL IE+
Sbjct: 509 FEGEILQDGEDYQYIERGETYC-LYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 565
Score = 54.0 bits (124), Expect = 5e-06
Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 1383 EEDVLSDEKTSDVEEF----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
EE + + T++ EE AP K L + + + +R K G PKP++ W +G
Sbjct: 453 EEGSIMNGSTAEDEEQTRSGAPWFKKPLKNT-SVVDSEPVRFTVKVTGEPKPEITWWFEG 511
Query: 1439 TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L +YQ E + T L +PE + +D GE + +A N+ G A+ L++ES
Sbjct: 512 EILQDGEDYQYIERGE-TYCLYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 565
Score = 41.5 bits (93), Expect = 0.029
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF-IIENKENRTTCT 1581
P F K + V + E V F +G P PEI W+ + ++++ E + IE E T C
Sbjct: 474 PWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWWFEGEILQDGEDYQYIERGE--TYCL 531
Query: 1582 -IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + + G Y CKAV++ G A + L +
Sbjct: 532 YLPETFPEDGGEYMCKAVNNKGSAASTCILTI 563
>BC114444-1|AAI14445.1| 567|Homo sapiens NEXN protein protein.
Length = 567
Score = 74.9 bits (176), Expect = 3e-12
Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 3/118 (2%)
Query: 1257 ENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF 1316
E GS+ ++ EEQT AP PL+NT+V+D E + K+ G P P+I W+
Sbjct: 451 EEEEGSIMNGSTAEDEEQT--RSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWW 508
Query: 1317 HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
++++ D + C +++ E FPE G Y C A N G ++ CIL IE+
Sbjct: 509 FEGEILQDGEDYQYIERGETYC-LYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 565
Score = 54.0 bits (124), Expect = 5e-06
Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 1383 EEDVLSDEKTSDVEEF----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
EE + + T++ EE AP K L + + + +R K G PKP++ W +G
Sbjct: 453 EEGSIMNGSTAEDEEQTRSGAPWFKKPLKNT-SVVDSEPVRFTVKVTGEPKPEITWWFEG 511
Query: 1439 TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L +YQ E + T L +PE + +D GE + +A N+ G A+ L++ES
Sbjct: 512 EILQDGEDYQYIERGE-TYCLYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 565
Score = 41.5 bits (93), Expect = 0.029
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF-IIENKENRTTCT 1581
P F K + V + E V F +G P PEI W+ + ++++ E + IE E T C
Sbjct: 474 PWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWWFEGEILQDGEDYQYIERGE--TYCL 531
Query: 1582 -IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + + G Y CKAV++ G A + L +
Sbjct: 532 YLPETFPEDGGEYMCKAVNNKGSAASTCILTI 563
>BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein.
Length = 637
Score = 74.9 bits (176), Expect = 3e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 66.9 bits (156), Expect = 7e-10
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G PTP + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
>BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein.
Length = 558
Score = 74.9 bits (176), Expect = 3e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 66.9 bits (156), Expect = 7e-10
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G PTP + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
>BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein.
Length = 305
Score = 74.9 bits (176), Expect = 3e-12
Identities = 67/270 (24%), Positives = 119/270 (44%), Gaps = 33/270 (12%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETAR--DITISRQKSGLC 1338
AP PL++ V++G + I G P P++ WF + ++I T+ + IS G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFS-DGRA 63
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I +G Y A+N G+ ++ L ++A E
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA---------------------ETA 102
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P V+ L ++ T +G +RL+ + GIP P V++ R G E+ S ++QI + D S+
Sbjct: 103 PPNFVQRLQSM-TVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSL 161
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + E Y +D+G A N +G + A L V+ G +E + T + + +
Sbjct: 162 L-IAEAYPEDSGTYSVNATNSVGRATSTAELLVQ---GEEEVPAKKTKT----IVSTAQI 213
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSG 1548
++S T +++ I I T E + G
Sbjct: 214 SESRQTRIEKKIEAHFDARSIATVEMVIDG 243
Score = 66.9 bits (156), Expect = 7e-10
Identities = 58/215 (26%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE-ELDDGTS 1457
AP + L +VV EG EA G P P+V W R G + ST ++ DG +
Sbjct: 5 APTFTQPLQSVVVL-EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
LT+P V + ++G +A N G + A L V K
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------------------------K 98
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
A + P FV+ + V + V + +G PTP + +Y+D I++ F I + +
Sbjct: 99 AETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDL 158
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I +A + GTY+ A + +G A + A+L V
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/151 (25%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
++K G + +A N +G +++ +V+ +T P + L++ TV G ++ L
Sbjct: 70 VTKANSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQGSQVRLQV 125
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
++ G P P + ++ + I+++ D IS Q+ L + I EA+PE +G Y A+N G+
Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQIS-QEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
++ L ++ E VP+ + ++S + S+
Sbjct: 185 ATSTAELLVQGEEEVPAKKTKTIVSTAQISE 215
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD--ERFIIENKEN 1576
T PTF + + V E TFEA SG P PE+ W++D +VI T I +
Sbjct: 2 TTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDG 61
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
R TI TK G Y+ KA + G A + A+L V
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
>BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein
protein.
Length = 1263
Score = 74.1 bits (174), Expect = 4e-12
Identities = 77/331 (23%), Positives = 131/331 (39%), Gaps = 47/331 (14%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + PL V + + ++ G P P + W+ N+ L+E I + R +C +
Sbjct: 842 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMER-VGNVCSLE 900
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
I G Y C A N G+ S + D++ E+ R
Sbjct: 901 ISNIQKGEGGEYMCHAVNIIGEAK--------------SFANVDIMPQEE---------R 937
Query: 1402 IVKALPTVVTTTEGKLIRLE-AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+V ALP VT LE + P PQ L ++ +E ++E + I+T
Sbjct: 938 VV-ALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLE-----VELSEKDVKEFEKQVKIVT 991
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+PE D H + ++ L + + R+ E +EL+ L+ +
Sbjct: 992 VPEFTPD-----------HKSMIVSLDVLPFNFVDPNMDSREGE----DKELKIDLEVFE 1036
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE-RFIIENKENRTT 1579
P F+ I ++ E F+ G PTPE+ WYK+ I D +++I ++ T
Sbjct: 1037 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYT 1096
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
I+ TY C+AV+ +G A+ + L
Sbjct: 1097 LKIRNVCLSDSATYRCRAVNCVGEAICRGFL 1127
Score = 60.1 bits (139), Expect = 8e-08
Identities = 51/226 (22%), Positives = 88/226 (38%), Gaps = 18/226 (7%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + P+ + + + C ++G P P++ W+ IE + ++ G +
Sbjct: 1039 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSYTLK 1098
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEY-----------VPSVSEEDVLSDE 1390
I+ + Y+C A N G+ L + E + S+ EE VL
Sbjct: 1099 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 1158
Query: 1391 KTSDVEEF-----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST 1445
T EF PR +K + G + G P+P V W + G +L+Q
Sbjct: 1159 YTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVRGSPRPTVYWYKDG-KLVQGR 1216
Query: 1446 EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ +EE G L + + + D GE A N G+ + AAL++
Sbjct: 1217 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 1262
Score = 54.0 bits (124), Expect = 5e-06
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKEN 1576
K + P+F++ + +V+E + F G P P + WY++ ++ DER +E N
Sbjct: 836 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 895
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I K G Y C AV+ IG A + A + +
Sbjct: 896 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 931
Score = 54.0 bits (124), Expect = 5e-06
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 18/257 (7%)
Query: 1370 LNIEAYEYV-PSVSEEDVLSDEKTSDVE--EFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
L++ + +V P++ + E D+E E PR + + + + IG
Sbjct: 1006 LDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAV-FKCSVIG 1064
Query: 1427 IPKPQVRWLRQGTELL-QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTAT 1485
IP P+V+W ++ + + +Y I E + G+ L + V D+ A N +G
Sbjct: 1065 IPTPEVKWYKEYMCIEPDNIKYVISE-EKGSYTLKIRNVCLSDSATYRCRAVNCVGEAIC 1123
Query: 1486 IAALSV---ESIVGTQEYRKPEWVTHMEELQAALKATQSV---------PTFVKEIIPER 1533
L++ E + K + MEEL T S P F+K I
Sbjct: 1124 RGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCY 1183
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
F+ + G+P P + WYKD K+++ + E+ I K EG Y
Sbjct: 1184 APIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEY 1243
Query: 1594 TCKAVSDIGLAVTKAKL 1610
C A + G+A + A L
Sbjct: 1244 RCVATNKSGMAESFAAL 1260
>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
preferentially expressed protein protein.
Length = 3094
Score = 74.1 bits (174), Expect = 4e-12
Identities = 68/268 (25%), Positives = 108/268 (40%), Gaps = 23/268 (8%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
+L ++ +D GV TC+ ++ S V APL LE+ V++G
Sbjct: 897 LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSL-----APLFTRLLEDVEVLEGRA 951
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
+CKI G P P + W H +E + ++ + RQ GL +HI E G+Y +A
Sbjct: 952 ARFDCKISGTPPPVVTWTHFGCPMEESENLRL-RQDGGLHSLHIAHVGSEDEGLYAVSAV 1010
Query: 1359 NQFGKCSTECILNIE-----------AYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
N G+ L +E E +PS+ EE + + + +F R ++ L
Sbjct: 1011 NTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFL-RPLQDLE 1069
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
+ K LE + G+P P + W G + S + ++ + D L P V
Sbjct: 1070 VGL----AKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD-VHRLVFPAVGPQ 1124
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIV 1495
G N LG A A L V +V
Sbjct: 1125 HAGVYKSVIANKLGKAACYAHLYVTDVV 1152
Score = 61.3 bits (142), Expect = 3e-08
Identities = 73/330 (22%), Positives = 128/330 (38%), Gaps = 30/330 (9%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC+A N G+ +E + + + VLAPL++ V GE C + G
Sbjct: 809 GFYTCKAVNEYGARQCEAR--LEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPT 866
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
++DW +L++ A C++ + + +G+Y C S + +
Sbjct: 867 DVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSAR 926
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + PS+ AP + L V EG+ R + K G P
Sbjct: 927 LTVR-----PSL-----------------APLFTRLLEDV-EVLEGRAARFDCKISGTPP 963
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P V W G + +S ++ + D G L + V +D G A N G A L
Sbjct: 964 PVVTWTHFGCPMEESENLRLRQ-DGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQL 1022
Query: 1490 SVES--IVGTQEYRKPEWVTHM-EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIY 1546
VE + K E + + EE + S+P F++ + V + E
Sbjct: 1023 YVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQV 1082
Query: 1547 SGNPTPEILWYKD-NKVIRTDERFIIENKE 1575
+G P P I W+ + +++ +D+R + + ++
Sbjct: 1083 TGLPYPTISWFHNGHRIQSSDDRRMTQYRD 1112
Score = 57.6 bits (133), Expect = 4e-07
Identities = 62/262 (23%), Positives = 103/262 (39%), Gaps = 29/262 (11%)
Query: 1379 PSVSEEDVLSDEKTSDVEEFAPRIVKALPTV-VTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
P+ E + D S EE V +P V G + L+ P PQV W +
Sbjct: 570 PTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKD 629
Query: 1438 GTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGT 1497
G+ L + + ++L + E D G + A N LG A+L+V T
Sbjct: 630 GSALRSEGRLLLRAEGERHTLL-LREARAADAGSYMATATNELGQATCAASLTVRPGGST 688
Query: 1498 QEYRKP-----EWVTHMEEL---------------------QAALKATQSVPTFVKEIIP 1531
+ P E+++ EE +++ +++ PTF ++
Sbjct: 689 SPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMD 748
Query: 1532 ERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE-NRTTCTIKKATKDLE 1590
+ V E + V G P P + W ++ + +R D+R E E I A +
Sbjct: 749 QSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDA 808
Query: 1591 GTYTCKAVSDIGLAVTKAKLQV 1612
G YTCKAV++ G +A+L+V
Sbjct: 809 GFYTCKAVNEYGARQCEARLEV 830
Score = 55.2 bits (127), Expect = 2e-06
Identities = 57/243 (23%), Positives = 91/243 (37%), Gaps = 30/243 (12%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP+ PL+N V G + L C I P P++ W H + + + R +
Sbjct: 591 EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSW-HKDGSALRSEGRLLLRAEGERHT 649
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYV-----PSVSEEDVLS------ 1388
+ ++EA AG Y TA+N+ G+ + L + P S+E+ LS
Sbjct: 650 LLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFP 709
Query: 1389 ------------------DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKP 1430
+ ++SD AP K + EG+ + + + G PKP
Sbjct: 710 EPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKP 769
Query: 1431 QVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALS 1490
V WLR + EE + G L + + D G +A N G A L
Sbjct: 770 VVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLE 829
Query: 1491 VES 1493
V +
Sbjct: 830 VRA 832
Score = 54.8 bits (126), Expect = 3e-06
Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L PL++ V + L C++ G P+P I WFHN I+++ D +++ + + +
Sbjct: 1059 PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD-VHRLV 1117
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVP 1379
P+ AG+YK +N+ GK + C ++ + VP
Sbjct: 1118 FPAVGPQHAGVYKSVIANKLGKAA--CYAHLYVTDVVP 1153
Score = 51.6 bits (118), Expect = 3e-05
Identities = 45/190 (23%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L + +V +G+ + ++ ++ G P P + W N + + + + GLC +
Sbjct: 740 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 799
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
I A AG Y C A N++G E L + A+ S++ L D
Sbjct: 800 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQD------------ 847
Query: 1402 IVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LT 1460
V G++ E G +V WL +G LLQ + + DG L
Sbjct: 848 --------VDVGAGEMALFECLVAGPTDVEVDWLCRG-RLLQPALLKCKMHFDGRKCKLL 898
Query: 1461 MPEVYQDDTG 1470
+ V++DD+G
Sbjct: 899 LTSVHEDDSG 908
Score = 49.6 bits (113), Expect = 1e-04
Identities = 24/91 (26%), Positives = 45/91 (49%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P+ L++ +++GE +L C P P I W ++K + + + I K G +
Sbjct: 2455 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2514
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I A AG+Y+C+A+N G ++ C + +
Sbjct: 2515 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2545
Score = 48.8 bits (111), Expect = 2e-04
Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 10/147 (6%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
+S+ +G +TC A N G T S+ E +AP + +E+ V GE
Sbjct: 1325 VSRRDMGALTCTARNRHG---TQTCSVTLELA----EAPRFESIMEDVEVGAGETARFAV 1377
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
+ G+P P I W+ +E L+ + ++ +++ C + + + G+Y CTA N G+
Sbjct: 1378 VVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE-CSLVVLSTGAQDGGVYTCTAQNLAGE 1436
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDE 1390
S C + + ++ E V DE
Sbjct: 1437 VS--CKAELAVHSAQTAMEVEGVGEDE 1461
Score = 45.6 bits (103), Expect = 0.002
Identities = 25/90 (27%), Positives = 36/90 (40%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F + V E F + G P P+I+WYKD ++ +EN + +
Sbjct: 1356 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVV 1415
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
G YTC A + G KA+L V
Sbjct: 1416 LSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1445
Score = 44.0 bits (99), Expect = 0.005
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN-KENRTTCT 1581
P F ++ + + E E T + + P P I W KD K +R++ II + K+ R +
Sbjct: 2455 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2514
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A K G Y C A + +G + + V
Sbjct: 2515 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2545
Score = 33.5 bits (73), Expect = 7.6
Identities = 26/117 (22%), Positives = 42/117 (35%), Gaps = 1/117 (0%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
S S ++ L + +F P L V EG+ L P P + W++
Sbjct: 2435 SASVQEELGHQYVRSESDFPPVFHIKLKDQVLL-EGEAATLLCLPAACPAPHISWMKDKK 2493
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
L I DG +L++P + G A N LG + ++V + G
Sbjct: 2494 SLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPG 2550
>AK057954-1|BAB71622.1| 505|Homo sapiens protein ( Homo sapiens cDNA
FLJ25225 fis, clone STM00940, highly similar to Rattus
norvegicus s-nexilin mRNA. ).
Length = 505
Score = 74.1 bits (174), Expect = 4e-12
Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 3/118 (2%)
Query: 1257 ENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF 1316
E GS+ ++ EEQT AP PL+NT+V+D E + K+ G P P+I W+
Sbjct: 389 EEEEGSIMNGSTAEDEEQT--RSGAPWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWW 446
Query: 1317 HNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
++++ D + C +++ E FPE G Y C A N G ++ CIL IE+
Sbjct: 447 FEGEILQDGEDYQYIERGETHC-LYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 503
Score = 54.4 bits (125), Expect = 4e-06
Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 6/115 (5%)
Query: 1383 EEDVLSDEKTSDVEEF----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
EE + + T++ EE AP K L + + + +R K G PKP++ W +G
Sbjct: 391 EEGSIMNGSTAEDEEQTRSGAPWFKKPLKNT-SVVDSEPVRFTVKVTGEPKPEITWWFEG 449
Query: 1439 TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L +YQ E + T L +PE + +D GE + +A N+ G A+ L++ES
Sbjct: 450 EILQDGEDYQYIERGE-THCLYLPETFPEDGGEYMCKAVNNKGSAASTCILTIES 503
Score = 41.9 bits (94), Expect = 0.022
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF-IIENKENRTTCT 1581
P F K + V + E V F +G P PEI W+ + ++++ E + IE E
Sbjct: 412 PWFKKPLKNTSVVDSEPVRFTVKVTGEPKPEITWWFEGEILQDGEDYQYIERGETHCLYL 471
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ +D G Y CKAV++ G A + L +
Sbjct: 472 PETFPED-GGEYMCKAVNNKGSAASTCILTI 501
>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
Length = 2242
Score = 74.1 bits (174), Expect = 4e-12
Identities = 68/268 (25%), Positives = 108/268 (40%), Gaps = 23/268 (8%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
+L ++ +D GV TC+ ++ S V APL LE+ V++G
Sbjct: 45 LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSL-----APLFTRLLEDVEVLEGRA 99
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
+CKI G P P + W H +E + ++ + RQ GL +HI E G+Y +A
Sbjct: 100 ARFDCKISGTPPPVVTWTHFGCPMEESENLRL-RQDGGLHSLHIAHVGSEDEGLYAVSAV 158
Query: 1359 NQFGKCSTECILNIE-----------AYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
N G+ L +E E +PS+ EE + + + +F R ++ L
Sbjct: 159 NTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFL-RPLQDLE 217
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
+ K LE + G+P P + W G + S + ++ + D L P V
Sbjct: 218 VGL----AKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD-VHRLVFPAVGPQ 272
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIV 1495
G N LG A A L V +V
Sbjct: 273 HAGVYKSVIANKLGKAACYAHLYVTDVV 300
Score = 54.8 bits (126), Expect = 3e-06
Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L PL++ V + L C++ G P+P I WFHN I+++ D +++ + + +
Sbjct: 207 PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD-VHRLV 265
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVP 1379
P+ AG+YK +N+ GK + C ++ + VP
Sbjct: 266 FPAVGPQHAGVYKSVIANKLGKAA--CYAHLYVTDVVP 301
Score = 49.6 bits (113), Expect = 1e-04
Identities = 24/91 (26%), Positives = 45/91 (49%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P+ L++ +++GE +L C P P I W ++K + + + I K G +
Sbjct: 1603 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 1662
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I A AG+Y+C+A+N G ++ C + +
Sbjct: 1663 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 1693
Score = 48.8 bits (111), Expect = 2e-04
Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 10/147 (6%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNC 1303
+S+ +G +TC A N G T S+ E +AP + +E+ V GE
Sbjct: 473 VSRRDMGALTCTARNRHG---TQTCSVTLELA----EAPRFESIMEDVEVGAGETARFAV 525
Query: 1304 KILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGK 1363
+ G+P P I W+ +E L+ + ++ +++ C + + + G+Y CTA N G+
Sbjct: 526 VVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE-CSLVVLSTGAQDGGVYTCTAQNLAGE 584
Query: 1364 CSTECILNIEAYEYVPSVSEEDVLSDE 1390
S C + + ++ E V DE
Sbjct: 585 VS--CKAELAVHSAQTAMEVEGVGEDE 609
Score = 48.4 bits (110), Expect = 2e-04
Identities = 45/200 (22%), Positives = 83/200 (41%), Gaps = 6/200 (3%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
S +++++ + + AP + L V EG+ R + K G P P V W G
Sbjct: 63 STAKDELTCSARLTVRPSLAPLFTRLLEDV-EVLEGRAARFDCKISGTPPPVVTWTHFGC 121
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES--IVGT 1497
+ +S ++ + D G L + V +D G A N G A L VE +
Sbjct: 122 PMEESENLRLRQ-DGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAAS 180
Query: 1498 QEYRKPEWVTHM-EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILW 1556
K E + + EE + S+P F++ + V + E +G P P I W
Sbjct: 181 GPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISW 240
Query: 1557 YKD-NKVIRTDERFIIENKE 1575
+ + +++ +D+R + + ++
Sbjct: 241 FHNGHRIQSSDDRRMTQYRD 260
Score = 45.6 bits (103), Expect = 0.002
Identities = 25/90 (27%), Positives = 36/90 (40%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F + V E F + G P P+I+WYKD ++ +EN + +
Sbjct: 504 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVV 563
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
G YTC A + G KA+L V
Sbjct: 564 LSTGAQDGGVYTCTAQNLAGEVSCKAELAV 593
Score = 44.0 bits (99), Expect = 0.005
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIEN-KENRTTCT 1581
P F ++ + + E E T + + P P I W KD K +R++ II + K+ R +
Sbjct: 1603 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 1662
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I +A K G Y C A + +G + + V
Sbjct: 1663 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 1693
Score = 33.5 bits (73), Expect = 7.6
Identities = 26/117 (22%), Positives = 42/117 (35%), Gaps = 1/117 (0%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
S S ++ L + +F P L V EG+ L P P + W++
Sbjct: 1583 SASVQEELGHQYVRSESDFPPVFHIKLKDQVLL-EGEAATLLCLPAACPAPHISWMKDKK 1641
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVG 1496
L I DG +L++P + G A N LG + ++V + G
Sbjct: 1642 SLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPG 1698
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 73.7 bits (173), Expect = 6e-12
Identities = 68/263 (25%), Positives = 119/263 (45%), Gaps = 31/263 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 142 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 194
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A PE G+YKC A N
Sbjct: 195 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKND 253
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 254 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 313
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ +S ++E ++G S
Sbjct: 314 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG-SK 372
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLG 1481
LT+ Q+ G N LG
Sbjct: 373 LTILAARQEHCGCYTLLVENKLG 395
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 887 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 946
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 947 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 977
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 859 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 913
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 914 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 973
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 974 ELIVETM 980
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 887 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 946
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 947 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 990
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/246 (20%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+EK S+ + AP + L V EGK + L+ + P + W G + L++T++
Sbjct: 165 NEKRSESQGTAPAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFI 222
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTH 1508
I + +++ + +D G A N G ++V+ ++ + PE +
Sbjct: 223 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 282
Query: 1509 ME----------ELQAALKATQSVPTFVKEIIPERV----HEEEIVTFEAI-----YSGN 1549
E A +K + T K +P ++ ++++ E++ +G
Sbjct: 283 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 342
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
W K K I+ E +EN EN + TI A ++ G YT + +G +
Sbjct: 343 QPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN 402
Query: 1610 LQVFQR 1615
L V +
Sbjct: 403 LTVVDK 408
>AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens cDNA
FLJ34965 fis, clone NTONG2004308. ).
Length = 885
Score = 72.9 bits (171), Expect = 1e-11
Identities = 76/331 (22%), Positives = 131/331 (39%), Gaps = 47/331 (14%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + PL V + + ++ G P P + W+ N+ L+E I + R +C +
Sbjct: 464 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMER-VGNVCSLE 522
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPR 1401
I G Y C A N G+ S + D++ E+ R
Sbjct: 523 ISNIQKGEGGEYMCHAVNIIGEAK--------------SFANVDIMPQEE---------R 559
Query: 1402 IVKALPTVVTTTEGKLIRLE-AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+V ALP VT LE + P PQ L ++ +E ++E + I+T
Sbjct: 560 VV-ALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLE-----VELSEKDVKEFEKQVKIVT 613
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+P+ D H + ++ L + + R+ E +EL+ L+ +
Sbjct: 614 VPDFTPD-----------HKSMIVSLDVLPFNFVDPNMDSREGE----DKELKIDLEVFE 658
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE-RFIIENKENRTT 1579
P F+ I ++ E F+ G PTPE+ WYK+ I D +++I ++ T
Sbjct: 659 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHT 718
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
I+ TY C+AV+ +G A+ + L
Sbjct: 719 LKIRNVCLSDSATYRCRAVNCVGEAICRGFL 749
Score = 59.7 bits (138), Expect = 1e-07
Identities = 51/226 (22%), Positives = 88/226 (38%), Gaps = 18/226 (7%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + P+ + + + C ++G P P++ W+ IE + ++ G +
Sbjct: 661 PRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLK 720
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEY-----------VPSVSEEDVLSDE 1390
I+ + Y+C A N G+ L + E + S+ EE VL
Sbjct: 721 IRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSN 780
Query: 1391 KTSDVEEF-----APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST 1445
T EF PR +K + G + G P+P V W + G +L+Q
Sbjct: 781 YTDSFFEFQVVEGPPRFIKGISDCYAPI-GTAAYFQCLVRGSPRPTVYWYKDG-KLVQGR 838
Query: 1446 EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+ +EE G L + + + D GE A N G+ + AAL++
Sbjct: 839 RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTL 884
Score = 54.4 bits (125), Expect = 4e-06
Identities = 60/257 (23%), Positives = 101/257 (39%), Gaps = 18/257 (7%)
Query: 1370 LNIEAYEYV-PSVSEEDVLSDEKTSDVE--EFAPRIVKALPTVVTTTEGKLIRLEAKAIG 1426
L++ + +V P++ + E D+E E PR + + + + IG
Sbjct: 628 LDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAV-FKCSVIG 686
Query: 1427 IPKPQVRWLRQGTELL-QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTAT 1485
IP P+V+W ++ + + +Y I E + G+ L + V D+ A N +G
Sbjct: 687 IPTPEVKWYKEYMCIEPDNIKYVISE-EKGSHTLKIRNVCLSDSATYRCRAVNCVGEAIC 745
Query: 1486 IAALSV---ESIVGTQEYRKPEWVTHMEELQAALKATQSV---------PTFVKEIIPER 1533
L++ E + K + MEEL T S P F+K I
Sbjct: 746 RGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCY 805
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
F+ + G+P P + WYKD K+++ + E+ I K EG Y
Sbjct: 806 APIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEY 865
Query: 1594 TCKAVSDIGLAVTKAKL 1610
C A + G+A + A L
Sbjct: 866 RCVATNKSGMAESFAAL 882
Score = 54.0 bits (124), Expect = 5e-06
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKEN 1576
K + P+F++ + +V+E + F G P P + WY++ ++ DER +E N
Sbjct: 458 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGN 517
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I K G Y C AV+ IG A + A + +
Sbjct: 518 VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 553
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 72.5 bits (170), Expect = 1e-11
Identities = 104/378 (27%), Positives = 148/378 (39%), Gaps = 64/378 (16%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDG 1296
N+L K G+ C A S+ SGS I+ + PL L+ E+ T G
Sbjct: 101 NILHSRHHKPDEGLYQCEA-----SLGDSGS-IISRTAKVAVAGPLRFLSQTESVTAFMG 154
Query: 1297 ERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
+ + L C+++G P P I W N++ L D + SG + I P GIY+C
Sbjct: 155 DTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSG--ALQISRLQPGDIGIYRC 212
Query: 1356 TASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEG 1415
+A N A + +E +LSD F R P+ V EG
Sbjct: 213 SARN-------------PASSRTGNEAEVRILSDPGLHRQLYFLQR-----PSNVVAIEG 254
Query: 1416 KLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV-F 1474
K LE G P P WLR G E++Q + L G S L + V DD+G
Sbjct: 255 KDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKYSLL--GGSNLLISNVTDDDSGMYTCV 311
Query: 1475 EAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERV 1534
Y + ++A+ A L+V +V P ++ H L A
Sbjct: 312 VTYKNENISAS-AELTV--LV------PPWFLNHPSNLYA-------------------- 342
Query: 1535 HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
+E + FE SG P P + W K+ V+ + F I N I K EG Y
Sbjct: 343 YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LRILGVVKSDEGFYQ 399
Query: 1595 CKAVSDIGLAVTKAKLQV 1612
C A ++ G A T A+L V
Sbjct: 400 CVAENEAGNAQTSAQLIV 417
Score = 36.7 bits (81), Expect = 0.81
Identities = 36/145 (24%), Positives = 55/145 (37%), Gaps = 12/145 (8%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGE 1297
N+L N++ D G+ TC ++S S E T + P L N +
Sbjct: 294 NLLISNVTDDDSGMYTCVVTYKNENISASA-----ELTVLV--PPWFLNHPSNLYAYESM 346
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
I C + G+P P ++W N ++ + I G + I G Y+C A
Sbjct: 347 DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQI----VGGSNLRILGVVKSDEGFYQCVA 402
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVS 1382
N+ G T L I +PS S
Sbjct: 403 ENEAGNAQTSAQL-IVPKPAIPSSS 426
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 72.5 bits (170), Expect = 1e-11
Identities = 104/378 (27%), Positives = 148/378 (39%), Gaps = 64/378 (16%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDG 1296
N+L K G+ C A S+ SGS I+ + PL L+ E+ T G
Sbjct: 101 NILHSRHHKPDEGLYQCEA-----SLGDSGS-IISRTAKVAVAGPLRFLSQTESVTAFMG 154
Query: 1297 ERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
+ + L C+++G P P I W N++ L D + SG + I P GIY+C
Sbjct: 155 DTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSG--ALQISRLQPGDIGIYRC 212
Query: 1356 TASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEG 1415
+A N A + +E +LSD F R P+ V EG
Sbjct: 213 SARN-------------PASSRTGNEAEVRILSDPGLHRQLYFLQR-----PSNVVAIEG 254
Query: 1416 KLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV-F 1474
K LE G P P WLR G E++Q + L G S L + V DD+G
Sbjct: 255 KDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKYSLL--GGSNLLISNVTDDDSGMYTCV 311
Query: 1475 EAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERV 1534
Y + ++A+ A L+V +V P ++ H L A
Sbjct: 312 VTYKNENISAS-AELTV--LV------PPWFLNHPSNLYA-------------------- 342
Query: 1535 HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
+E + FE SG P P + W K+ V+ + F I N I K EG Y
Sbjct: 343 YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LRILGVVKSDEGFYQ 399
Query: 1595 CKAVSDIGLAVTKAKLQV 1612
C A ++ G A T A+L V
Sbjct: 400 CVAENEAGNAQTSAQLIV 417
Score = 36.7 bits (81), Expect = 0.81
Identities = 36/145 (24%), Positives = 55/145 (37%), Gaps = 12/145 (8%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGE 1297
N+L N++ D G+ TC ++S S E T + P L N +
Sbjct: 294 NLLISNVTDDDSGMYTCVVTYKNENISASA-----ELTVLV--PPWFLNHPSNLYAYESM 346
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
I C + G+P P ++W N ++ + I G + I G Y+C A
Sbjct: 347 DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQI----VGGSNLRILGVVKSDEGFYQCVA 402
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVS 1382
N+ G T L I +PS S
Sbjct: 403 ENEAGNAQTSAQL-IVPKPAIPSSS 426
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 72.5 bits (170), Expect = 1e-11
Identities = 104/378 (27%), Positives = 148/378 (39%), Gaps = 64/378 (16%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDG 1296
N+L K G+ C A S+ SGS I+ + PL L+ E+ T G
Sbjct: 35 NILHSRHHKPDEGLYQCEA-----SLGDSGS-IISRTAKVAVAGPLRFLSQTESVTAFMG 88
Query: 1297 ERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
+ + L C+++G P P I W N++ L D + SG + I P GIY+C
Sbjct: 89 DTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSG--ALQISRLQPGDIGIYRC 146
Query: 1356 TASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEG 1415
+A N A + +E +LSD F R P+ V EG
Sbjct: 147 SARN-------------PASSRTGNEAEVRILSDPGLHRQLYFLQR-----PSNVVAIEG 188
Query: 1416 KLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV-F 1474
K LE G P P WLR G E++Q + L G S L + V DD+G
Sbjct: 189 KDAVLEGCVSGYPPPSFTWLR-GEEVIQLRSKKYSLL--GGSNLLISNVTDDDSGMYTCV 245
Query: 1475 EAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERV 1534
Y + ++A+ A L+V +V P ++ H L A
Sbjct: 246 VTYKNENISAS-AELTV--LV------PPWFLNHPSNLYA-------------------- 276
Query: 1535 HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
+E + FE SG P P + W K+ V+ + F I N I K EG Y
Sbjct: 277 YESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSN---LRILGVVKSDEGFYQ 333
Query: 1595 CKAVSDIGLAVTKAKLQV 1612
C A ++ G A T A+L V
Sbjct: 334 CVAENEAGNAQTSAQLIV 351
Score = 36.7 bits (81), Expect = 0.81
Identities = 36/145 (24%), Positives = 55/145 (37%), Gaps = 12/145 (8%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGE 1297
N+L N++ D G+ TC ++S S E T + P L N +
Sbjct: 228 NLLISNVTDDDSGMYTCVVTYKNENISASA-----ELTVLV--PPWFLNHPSNLYAYESM 280
Query: 1298 RISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
I C + G+P P ++W N ++ + I G + I G Y+C A
Sbjct: 281 DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQI----VGGSNLRILGVVKSDEGFYQCVA 336
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVS 1382
N+ G T L I +PS S
Sbjct: 337 ENEAGNAQTSAQL-IVPKPAIPSSS 360
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 72.1 bits (169), Expect = 2e-11
Identities = 70/273 (25%), Positives = 121/273 (44%), Gaps = 31/273 (11%)
Query: 1241 EENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERIS 1300
+E + KD+ V C+ + +G++ E+++ G AP L++ V +G+++
Sbjct: 142 KEELKKDVKNDVNCKRGH-------AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 194
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
L C++ P I W N K ++T + I +S Q+ LC + I++A PE G+YKC A N
Sbjct: 195 LQCQVSSDPPATIIWTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKND 253
Query: 1361 FGKCSTECILNIE---AYEYV---------PSVSEEDVLSDEKTSDVEEF-APRI-VKAL 1406
G+ C + ++ A E P S VL E + V++ AP+ KA
Sbjct: 254 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSPPPVLGTESDATVKKKPAPKTPPKAA 313
Query: 1407 --PTVVTTTE------GKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
P ++ E G+ + L K G W++ ++ +S ++E ++G S
Sbjct: 314 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG-SK 372
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
LT+ Q+ G N G LSV
Sbjct: 373 LTILAGRQEHCGCYTLLVENKSGSRQAQVNLSV 405
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 886 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 945
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 946 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 976
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 886 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 945
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 946 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 989
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 879 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 934
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 935 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 979
Score = 42.3 bits (95), Expect = 0.016
Identities = 22/92 (23%), Positives = 45/92 (48%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
+ P F +++ V E + + + S +P I+W + K ++T + I+ + + +
Sbjct: 174 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 233
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+I+KA + G Y C A +D G A ++ V
Sbjct: 234 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 265
>BC008648-1|AAH08648.1| 358|Homo sapiens Unknown (protein for
IMAGE:3866238) protein.
Length = 358
Score = 67.7 bits (158), Expect = 4e-10
Identities = 84/326 (25%), Positives = 135/326 (41%), Gaps = 30/326 (9%)
Query: 193 DTTSSKLETKSWRKPRLEESLEEVGPTKGVN--EPEVCHWRKPKTSEILKDKNEEEIRVQ 250
+ S E KS K + E P K + + E K K+ E K +EE +
Sbjct: 5 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEEAKSP 64
Query: 251 EMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKE-KIEDVALKPVRKDSLMD 309
E K KA E K K K P EA P K KSP+++E K + A PV++++
Sbjct: 65 EKAKSPVKA-EAKSPEKAKSPVKAEAKS--PEKA-KSPVKEEAKSPEKAKSPVKEEAKSP 120
Query: 310 EKSSEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQK 369
EK+ S ++ E + EK +S + + + EK E EE K + + +E+ K
Sbjct: 121 EKAK--SPVKEEAKTPEKAKSPVKEEAKAPEK----EIPKKEEVKSPVKEEEKPQEVKVK 174
Query: 370 EVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLR 429
E K P +K+SK+ E K+ KP + +E +
Sbjct: 175 EPPKKAEEEKAPAT----------PKTEEKKDSKKEE--APKKEAPKPKVEEKKEPAVEK 222
Query: 430 PTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNA 489
P K K +KE+ ED PT ++ ++ + A ++ K+E K E +
Sbjct: 223 P-KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 281
Query: 490 PEERKWPTGKRQPKEETPQEEVVLKP 515
P E+K + P+++ +EE KP
Sbjct: 282 PAEKK----EAAPEKKDTKEEKAKKP 303
Score = 53.2 bits (122), Expect = 9e-06
Identities = 88/364 (24%), Positives = 148/364 (40%), Gaps = 29/364 (7%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K ++ + + K+ +E K + + E +S + K E K
Sbjct: 3 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEEAK 62
Query: 203 SWRKPRLEESLEEVGPTKG-------VNEPEVCH---WRKPKTSEILKDKNEEEIRVQEM 252
S K + E P K PE + K+ E K +EE + E
Sbjct: 63 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 122
Query: 253 KKQSTKALEVKDESKQKIPWTQEA---IKLRPTKVE-KSPI-EKEKIEDVALKPVRKDSL 307
K K E K K K P +EA K P K E KSP+ E+EK ++V +K K +
Sbjct: 123 AKSPVKE-EAKTPEKAKSPVKEEAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA- 180
Query: 308 MDEKSSEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEIT 367
+E+ + + E++ ++K+E+ ++ +P + K + E+ KES + ++ E
Sbjct: 181 -EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK--KEPAVEKPKESKVEAKKEEAED 237
Query: 368 QKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIK 427
+K+V KP TE KE +D K+ KP+ + A +
Sbjct: 238 KKKVPTP----EKEAPAKVEVKEDAKPKEKTEVAKKEPDD-AKAKEPSKPA-EKKEAAPE 291
Query: 428 LRPTKMEKT--PIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVS 485
+ TK EK P EK K E + + S + A KS+ D +K+ P+K +
Sbjct: 292 KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD-QKDSKPPEKAT 350
Query: 486 ENNA 489
E+ A
Sbjct: 351 EDKA 354
Score = 37.5 bits (83), Expect = 0.47
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 15/159 (9%)
Query: 752 EERKWPSGKRRP-KEET--PQKEV-LLEHVXXXXXXXXXXXXXNVLKDVSETEKESKERG 807
EE K P + P KEE P+KE+ E V V + + E+E
Sbjct: 129 EEAKTPEKAKSPVKEEAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 188
Query: 808 DKIQTK-DTRKSSIPWTQEAIKLRPTKKRFYVRRKTRRSYTLRALVDKIHTEEQELKDKE 866
K + K D++K P +EA K + +K+ K + S K+ +++E +DK+
Sbjct: 189 PKTEEKKDSKKEEAP-KKEAPKPKVEEKKEPAVEKPKES--------KVEAKKEEAEDKK 239
Query: 867 RVQEIRDEQMKTDKPVEDAMPEERKWPTGKRRPKEATSQ 905
+V E + EDA P+E K K+ P +A ++
Sbjct: 240 KVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAK 277
>BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein.
Length = 179
Score = 67.3 bits (157), Expect = 5e-10
Identities = 52/204 (25%), Positives = 91/204 (44%), Gaps = 28/204 (13%)
Query: 1293 VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGI 1352
+ +G+ + C+I G P P+I+WF N I + +++ISR ++ + + I+ A +G
Sbjct: 2 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLEIRNASVSDSGK 60
Query: 1353 YKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
Y A N G+CS L V P+I +ALP+ ++
Sbjct: 61 YTIKAKNFRGQCSATASLM-----------------------VLRIPPKI-EALPSDISI 96
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTEL--LQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
EGK++ + G P P+V W G ++ + + IE DD T+++ M +V + D G
Sbjct: 97 DEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIM-DVQKQDGG 155
Query: 1471 EIVFEAYNHLGVTATIAALSVESI 1494
N G + + + SI
Sbjct: 156 LYTLSLGNEFGSDSATVNIHIRSI 179
Score = 45.6 bits (103), Expect = 0.002
Identities = 26/81 (32%), Positives = 37/81 (45%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
++E + V F SG P+PEI W+K+N I I N + I+ A+ G Y
Sbjct: 2 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 61
Query: 1594 TCKAVSDIGLAVTKAKLQVFQ 1614
T KA + G A L V +
Sbjct: 62 TIKAKNFRGQCSATASLMVLR 82
Score = 45.2 bits (102), Expect = 0.002
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE--RFIIENKENRTTCTIKKATKDLEG 1591
+ E +++T ++G PTPE+ W + I + E RF IEN ++ TT I K G
Sbjct: 96 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGG 155
Query: 1592 TYTCKAVSDIG 1602
YT ++ G
Sbjct: 156 LYTLSLGNEFG 166
Score = 37.5 bits (83), Expect = 0.47
Identities = 29/133 (21%), Positives = 57/133 (42%), Gaps = 7/133 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N S G T +A+NF G S + S +V P + A + ++ +G+ +++
Sbjct: 52 NASVSDSGKYTIKAKNFRGQCSATASLMVLRIP------PKIEALPSDISIDEGKVLTVA 105
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKS-GLCEIHIKEAFPEMAGIYKCTASNQF 1361
C G P P++ W + I + + + L + I + + G+Y + N+F
Sbjct: 106 CAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEF 165
Query: 1362 GKCSTECILNIEA 1374
G S ++I +
Sbjct: 166 GSDSATVNIHIRS 178
>BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 66.9 bits (156), Expect = 7e-10
Identities = 57/238 (23%), Positives = 101/238 (42%), Gaps = 27/238 (11%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
S S DV +D+ + + PR ++ +P ++ EG+ R++ K G+P P V W G
Sbjct: 231 STSRGDV-NDQDAIQEKFYPPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 288
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ +++ + G L V D G A N G A +V+ V +E
Sbjct: 289 TVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE----ATFTVQLDVLAKE 344
Query: 1500 YRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKD 1559
+++ P F+ + ++V E + V E S P P++ W ++
Sbjct: 345 HKR-------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRN 385
Query: 1560 NKVIR--TDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
N++++ TD + ++ R T IK K G YT AV++ G+ +L V R
Sbjct: 386 NEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443
Score = 57.6 bits (133), Expect = 4e-07
Identities = 49/205 (23%), Positives = 89/205 (43%), Gaps = 23/205 (11%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
EN ++ +G ++ K+ G P P + W+ N + +++ + + GL + +
Sbjct: 257 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 316
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ + L++ A E+ K + + + P+ K L
Sbjct: 317 DAGAYACVAKNRAGEATFTVQLDVLAKEH-------------KRAPMFIYKPQSKKVL-- 361
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM--PEVYQ 1466
EG ++LE + IP P++ W ++ E++Q +I D T +T+ +V +
Sbjct: 362 -----EGDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 415
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSV 1491
D G A N GVT L V
Sbjct: 416 KDAGWYTVSAVNEAGVTTCNTRLDV 440
Score = 50.8 bits (116), Expect = 5e-05
Identities = 36/154 (23%), Positives = 74/154 (48%), Gaps = 5/154 (3%)
Query: 1223 STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVS-TSGSSIVEEQTCIDGDA 1281
S +L I+ +++ E + G C A+N AG + T ++ ++ A
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---HKRA 348
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEI 1340
P+ + ++ V++G+ + L C+I P PK+ W N ++++ D I++ + +G +
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTL 408
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
IK+ + AG Y +A N+ G + L++ A
Sbjct: 409 LIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 442
>AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 66.9 bits (156), Expect = 7e-10
Identities = 57/238 (23%), Positives = 101/238 (42%), Gaps = 27/238 (11%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
S S DV +D+ + + PR ++ +P ++ EG+ R++ K G+P P V W G
Sbjct: 231 STSRGDV-NDQDAIQEKFYPPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 288
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ +++ + G L V D G A N G A +V+ V +E
Sbjct: 289 TVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE----ATFTVQLDVLAKE 344
Query: 1500 YRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKD 1559
+++ P F+ + ++V E + V E S P P++ W ++
Sbjct: 345 HKR-------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRN 385
Query: 1560 NKVIR--TDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
N++++ TD + ++ R T IK K G YT AV++ G+ +L V R
Sbjct: 386 NEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443
Score = 57.6 bits (133), Expect = 4e-07
Identities = 49/205 (23%), Positives = 89/205 (43%), Gaps = 23/205 (11%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
EN ++ +G ++ K+ G P P + W+ N + +++ + + GL + +
Sbjct: 257 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 316
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ + L++ A E+ K + + + P+ K L
Sbjct: 317 DAGAYACVAKNRAGEATFTVQLDVLAKEH-------------KRAPMFIYKPQSKKVL-- 361
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM--PEVYQ 1466
EG ++LE + IP P++ W ++ E++Q +I D T +T+ +V +
Sbjct: 362 -----EGDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 415
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSV 1491
D G A N GVT L V
Sbjct: 416 KDAGWYTVSAVNEAGVTTCNTRLDV 440
Score = 50.8 bits (116), Expect = 5e-05
Identities = 36/154 (23%), Positives = 74/154 (48%), Gaps = 5/154 (3%)
Query: 1223 STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVS-TSGSSIVEEQTCIDGDA 1281
S +L I+ +++ E + G C A+N AG + T ++ ++ A
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---HKRA 348
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEI 1340
P+ + ++ V++G+ + L C+I P PK+ W N ++++ D I++ + +G +
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTL 408
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
IK+ + AG Y +A N+ G + L++ A
Sbjct: 409 LIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 442
>AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein protein.
Length = 498
Score = 66.9 bits (156), Expect = 7e-10
Identities = 57/238 (23%), Positives = 101/238 (42%), Gaps = 27/238 (11%)
Query: 1380 SVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
S S DV +D+ + + PR ++ +P ++ EG+ R++ K G+P P V W G
Sbjct: 231 STSRGDV-NDQDAIQEKFYPPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 288
Query: 1440 ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ +++ + G L V D G A N G A +V+ V +E
Sbjct: 289 TVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE----ATFTVQLDVLAKE 344
Query: 1500 YRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKD 1559
+++ P F+ + ++V E + V E S P P++ W ++
Sbjct: 345 HKR-------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRN 385
Query: 1560 NKVIR--TDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
N++++ TD + ++ R T IK K G YT AV++ G+ +L V R
Sbjct: 386 NEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443
Score = 57.6 bits (133), Expect = 4e-07
Identities = 49/205 (23%), Positives = 89/205 (43%), Gaps = 23/205 (11%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
EN ++ +G ++ K+ G P P + W+ N + +++ + + GL + +
Sbjct: 257 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 316
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
AG Y C A N+ G+ + L++ A E+ K + + + P+ K L
Sbjct: 317 DAGAYACVAKNRAGEATFTVQLDVLAKEH-------------KRAPMFIYKPQSKKVL-- 361
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTM--PEVYQ 1466
EG ++LE + IP P++ W ++ E++Q +I D T +T+ +V +
Sbjct: 362 -----EGDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 415
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSV 1491
D G A N GVT L V
Sbjct: 416 KDAGWYTVSAVNEAGVTTCNTRLDV 440
Score = 50.8 bits (116), Expect = 5e-05
Identities = 36/154 (23%), Positives = 74/154 (48%), Gaps = 5/154 (3%)
Query: 1223 STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVS-TSGSSIVEEQTCIDGDA 1281
S +L I+ +++ E + G C A+N AG + T ++ ++ A
Sbjct: 292 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---HKRA 348
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEI 1340
P+ + ++ V++G+ + L C+I P PK+ W N ++++ D I++ + +G +
Sbjct: 349 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTL 408
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
IK+ + AG Y +A N+ G + L++ A
Sbjct: 409 LIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 442
>AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein
protein.
Length = 1232
Score = 66.5 bits (155), Expect = 9e-10
Identities = 110/486 (22%), Positives = 181/486 (37%), Gaps = 67/486 (13%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA--RDITISRQKSGLC 1338
A +L + TV +GE +C G P P + W +++ T+ +T ++ KS
Sbjct: 369 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTF- 427
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE-------AYEYVPSV--------SE 1383
EI +A E G Y N GK E L I+ A P V S
Sbjct: 428 EISSVQASDE--GNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSP 485
Query: 1384 EDVLSDEKTSDVEEFAPRIVKALPTVVTTTE-------------GKLIRLEA-KAIG--- 1426
E V S ++ E P+ V T T TE + ++ EA K I
Sbjct: 486 EAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLT 545
Query: 1427 -------IPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
+ +V W + G +L ++ +Q DGT L + + + D GE V E
Sbjct: 546 CVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGE 605
Query: 1480 LGVTAT------IAALSV-ESIVGTQEYRKPE------WVTHMEELQAALKATQSVPTFV 1526
G + T A S+ E + E +K + VT E +A + S P V
Sbjct: 606 GGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAP-EPISSKPVIV 664
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+ V + + F +G P P +W KD K I ++ + + I K
Sbjct: 665 TGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTD 724
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXXXXXXXXXXXXXXXXXXXXEEESVGVED 1646
G YTC + G + KL + ++++V E+
Sbjct: 725 TSDSGLYTCTVKNSAGSVSSSCKLTI----KAIKDTEAQKVSTQKTSEITPQKKAVVQEE 780
Query: 1647 TLDFATVSEVQALDKQHSTDK--VKKRKAKIVVSESEHIETEDIALQKKV--DEKTKGIP 1702
A SE + + S +K +K+ +K+++SE E ++ +L+K + +E TK
Sbjct: 781 ISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKKSAATSLEKSIVHEEITKTSQ 839
Query: 1703 VEEKAK 1708
E+ +
Sbjct: 840 ASEEVR 845
Score = 59.7 bits (138), Expect = 1e-07
Identities = 32/123 (26%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G++TC ++ G V + ++ DAP ++ + + +G+ + C+I G P
Sbjct: 914 GILTCISKTKEGIVKCQYDLTLSKEL---SDAPAFISQPRSQNINEGQNVLFTCEISGEP 970
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I+WF N I + +++ISR ++ + + I+ A +G Y A N G+CS
Sbjct: 971 SPEIEWFKNNLPISISSNVSISRSRN-VYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 1029
Query: 1370 LNI 1372
L +
Sbjct: 1030 LMV 1032
Score = 58.8 bits (136), Expect = 2e-07
Identities = 62/232 (26%), Positives = 96/232 (41%), Gaps = 29/232 (12%)
Query: 1381 VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V EE + + + +V A +KA T ++ EG+ + L+A G +W+ G E
Sbjct: 830 VHEEITKTSQASEEVRTHAE--IKAFSTQMSINEGQRLVLKANIAGAT--DAKWVLNGVE 885
Query: 1441 LLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEY 1500
L S EY+ + LT+ + D G + T + + E IV Q Y
Sbjct: 886 LTNSEEYRYG-VSGSDQTLTIKQASHRDEGIL------------TCISKTKEGIVKCQ-Y 931
Query: 1501 RKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
+T +EL A P F+ + + ++E + V F SG P+PEI W+K+N
Sbjct: 932 D----LTLSKELSDA-------PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNN 980
Query: 1561 KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I I N + I+ A+ G YT KA + G A L V
Sbjct: 981 LPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 1032
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 8/105 (7%)
Query: 1506 VTHMEELQAA----LKA-TQSVPTFVKEIIPE-RVHEEEIVTFEAIYSGNPTPEILWYKD 1559
+++M +L+++ LKA + +P ++ + + + E +++T ++G PTPE+ W
Sbjct: 1115 ISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG 1174
Query: 1560 NKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ I + E RF IEN ++ TT I K G YT ++ G
Sbjct: 1175 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 1219
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL--LQSTEYQIEELDDGTS 1457
P ++ALP+ ++ EGK++ + G P P+V W G ++ + + IE DD T+
Sbjct: 1137 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 1196
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
++ M +V + D G N G + + + SI
Sbjct: 1197 LIIM-DVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 1232
Score = 39.1 bits (87), Expect = 0.15
Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 16/195 (8%)
Query: 1366 TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL-------PTVVTTTEGKLI 1418
TE ++ +YE+ S + +EK+ + + +I L P +T EG+
Sbjct: 328 TETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESA 387
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
R G P P V WLR+G L S +Q+ S + V D G N
Sbjct: 388 RFSCDTDGEPVPTVTWLRKGQVLSTSARHQV-TTTKYKSTFEISSVQASDEGNYSVVVEN 446
Query: 1479 HLGVTATIAALSVESIVGTQE-YRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
G L+++ T++ P V E + +A +S P VK PE H +
Sbjct: 447 SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKS-PKRVKS--PEPSHPK 503
Query: 1538 EIVTFEAIYSGNPTP 1552
+ E PTP
Sbjct: 504 AVSPTET----KPTP 514
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/114 (18%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDIT 1329
++ +Q AP + + + V G+ + +P ++ W+HN ++ + I
Sbjct: 171 VLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH 230
Query: 1330 ISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE 1383
+ SG+ + I + + +G Y+ +N G+ S L++ +Y S+
Sbjct: 231 YTNT-SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQ 283
>X15306-1|CAA33366.1| 1020|Homo sapiens heavy neurofilament subunit
protein.
Length = 1020
Score = 66.1 bits (154), Expect = 1e-09
Identities = 85/373 (22%), Positives = 145/373 (38%), Gaps = 21/373 (5%)
Query: 149 VQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPR 208
V+E ++ K E K +V + E E +S + K E KS K +
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Query: 209 LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQ 268
E P K + + + K+ E K +EE + E K K E K K
Sbjct: 668 SPVKAEAKSPEKAKSPVKA----EAKSPEKAKSPVKEEAKSPEKAKSPVKE-EAKSPEKA 722
Query: 269 KIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER------ 322
K P +EA P K KSP+++E K K +D KS E E
Sbjct: 723 KSPVKEEA--KTPEKA-KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPAD 779
Query: 323 QITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXX 382
+ EK +S + +++ EK K ++ ++ K+ + + ++E + V+
Sbjct: 780 KFPEKAKSPVKEEVKSPEKAKSPLKADAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP 839
Query: 383 XXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEK 442
P +K+SK+ E K+ KP + +E +P K K +KE+
Sbjct: 840 KKAEEEKAPATPKTEEKKDSKKEE--APKKEAPKPKVEEKKEPAVEKP-KESKVEAKKEE 896
Query: 443 FEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQP 502
ED PT ++ ++ + A ++ K+E K E + P E+K + P
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK----EAAP 952
Query: 503 KEETPQEEVVLKP 515
+++ +EE KP
Sbjct: 953 EKKDTKEEKAKKP 965
Score = 49.6 bits (113), Expect = 1e-04
Identities = 98/477 (20%), Positives = 177/477 (37%), Gaps = 32/477 (6%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
+ H+KV+ + K+ K SEK+ ++ E+T + + E E +
Sbjct: 432 VSTHIKVKSEEKIKVVEK----SEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 203 SWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTKALE 261
+ E EE TK E K S + ++ K+ E + E K+++ E
Sbjct: 488 GGEEEEAEGGEEE---TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE-KEEAKSPAE 543
Query: 262 VKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALK-PVRKDSLMDEKSSEISELQN 320
VK K K P +EA K P KSP ++E +K P + S E++ +E ++
Sbjct: 544 VKSPEKAKSPAKEEA-KSPPE--AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600
Query: 321 ERQ----ITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRR----QREEITQKEVA 372
+ + E+ +S E + E+ K + S E +S K ++ + +KE A
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA 660
Query: 373 LKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTK 432
+ K + E +S E ++ + P + + + +
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 433 MEKTPIEKE-KFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPE 491
K+P+++E K + P ++++ E + K+ D++ E K E +P
Sbjct: 721 KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL--DVKSPEAKTPAKEEARSPA 778
Query: 492 ERKWPTGKRQP-KEETPQEEVVLKPTRXXXXXXXXXXXXXXWPSGKRRPKEETPQEEVVL 550
+ K+P + P KEE E P + + +EE PQE V
Sbjct: 779 D-KFPEKAKSPVKEEVKSPEKAKSPLKADAKAPEKEIPKKEEVKSPVK-EEEKPQEVKV- 835
Query: 551 XXXXXXXXXXXXXXXXXXXXXVKKEKQIEDATPEERKWP--SGKRRPKEETPQEEVV 605
KK+ + E+A +E P K+ P E P+E V
Sbjct: 836 --KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890
Score = 37.1 bits (82), Expect = 0.61
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 14/192 (7%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K QEV K+ PK E+K T E + K E + + +
Sbjct: 824 VKEEEKPQEV---KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880
Query: 203 SWRKPR---LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTK 258
+ KP+ +E EE K V PE P E+ +D K +E+ V + + K
Sbjct: 881 AVEKPKESKVEAKKEEAEDKKKVPTPEK---EAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISEL 318
A E +++K + A + + TK EK+ +EK + A +L E S +E
Sbjct: 938 AKEPSKPAEKK----EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Query: 319 QNERQITEKKES 330
+ T++K+S
Sbjct: 994 AEKSSSTDQKDS 1005
Score = 35.9 bits (79), Expect = 1.4
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 17/159 (10%)
Query: 750 TPEERKWP--SGKRRPKEETPQKEVLLEHVXXXXXXXXXXXXXNVLKDVSETEKESKERG 807
+PE+ K P + + P++E P+KE V V + + E+E
Sbjct: 795 SPEKAKSPLKADAKAPEKEIPKKE----EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 850
Query: 808 DKIQTK-DTRKSSIPWTQEAIKLRPTKKRFYVRRKTRRSYTLRALVDKIHTEEQELKDKE 866
K + K D++K P +EA K + +K+ K + S K+ +++E +DK+
Sbjct: 851 PKTEEKKDSKKEEAP-KKEAPKPKVEEKKEPAVEKPKES--------KVEAKKEEAEDKK 901
Query: 867 RVQEIRDEQMKTDKPVEDAMPEERKWPTGKRRPKEATSQ 905
+V E + EDA P+E K K+ P +A ++
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAK 939
>BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein.
Length = 1120
Score = 66.1 bits (154), Expect = 1e-09
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 4/116 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP+ PL NT + G +LNC + G P PKI W N+ +++ R S Q G+C
Sbjct: 1001 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ--GVC 1058
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA-YEYVPSVSEEDVLSDEKTS 1393
+ I++ P G Y C A N G EC L ++ Y+ V + + L ++ S
Sbjct: 1059 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQS 1114
Score = 53.2 bits (122), Expect = 9e-06
Identities = 28/90 (31%), Positives = 43/90 (47%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F + ++ T GNP P+I W K+ I D R+ + + + T I
Sbjct: 1003 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1062
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K + GTY CKAV+D+G + KL+V
Sbjct: 1063 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1092
Score = 39.9 bits (89), Expect = 0.087
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
+P +K+ RV E V + G P PE+ W KD I ++ I N E T
Sbjct: 797 IPRHLKQTYIRRVGEA--VNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIF 853
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
I+KA + G Y + D + +Q+ R
Sbjct: 854 IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 887
>X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein.
Length = 1123
Score = 65.3 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP+ PL NT + G +LNC + G P PKI W N+ +++ R S Q G+C
Sbjct: 1027 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ--GVC 1084
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ I++ P G Y C A N G EC L ++
Sbjct: 1085 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1119
Score = 53.2 bits (122), Expect = 9e-06
Identities = 28/90 (31%), Positives = 43/90 (47%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F + ++ T GNP P+I W K+ I D R+ + + + T I
Sbjct: 1029 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1088
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K + GTY CKAV+D+G + KL+V
Sbjct: 1089 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 39.9 bits (89), Expect = 0.087
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
+P +K+ RV E V + G P PE+ W KD I ++ I N E T
Sbjct: 823 IPRHLKQTYIRRVGEA--VNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIF 879
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
I+KA + G Y + D + +Q+ R
Sbjct: 880 IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 913
>BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein C,
slow type protein.
Length = 1123
Score = 65.3 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP+ PL NT + G +LNC + G P PKI W N+ +++ R S Q G+C
Sbjct: 1027 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ--GVC 1084
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ I++ P G Y C A N G EC L ++
Sbjct: 1085 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1119
Score = 53.2 bits (122), Expect = 9e-06
Identities = 28/90 (31%), Positives = 43/90 (47%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F + ++ T GNP P+I W K+ I D R+ + + + T I
Sbjct: 1029 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1088
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K + GTY CKAV+D+G + KL+V
Sbjct: 1089 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 39.9 bits (89), Expect = 0.087
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 1522 VPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCT 1581
+P +K+ RV E V + G P PE+ W KD I ++ I N E T
Sbjct: 823 IPRHLKQTYIRRVGEA--VNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIF 879
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
I+KA + G Y + D + +Q+ R
Sbjct: 880 IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 913
>AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein.
Length = 507
Score = 64.9 bits (151), Expect = 3e-09
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 13/157 (8%)
Query: 1256 AENFAGSVSTSGSS---IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
A AG +T GSS + E+ G P L + V +G R+ L+C ++G P P+
Sbjct: 242 ASEAAGGDTTPGSSPSSLYYEEPL--GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQ 299
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ W+ K +E + DI I Q L + I EAF E G Y C ASN +G ST
Sbjct: 300 VRWYCEGKELENSPDIHIV-QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDST------ 352
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEF-APRIVKALPT 1408
A Y+ VS D D ++ P V + PT
Sbjct: 353 SAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPT 389
Score = 58.4 bits (135), Expect = 2e-07
Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
EG ++L+ +GIP PQVRW +G EL S + I + + S LT+ E +++DTG
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHS-LTIAEAFEEDTGRYS 340
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ-SVPTFVKEIIPE 1532
A N G +T A + +E + + P + EE+ K + S P +IP
Sbjct: 341 CFASNIYGTDSTSAEIYIEGVSSSDSEGDP----NKEEMNRIQKPNEVSSPPTTSAVIPP 396
Query: 1533 RVHEEE 1538
V + +
Sbjct: 397 AVPQAQ 402
Score = 44.8 bits (101), Expect = 0.003
Identities = 17/54 (31%), Positives = 31/54 (57%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK 1334
AP+ L+N + +G+ + C++ G P PK++W+ LIE + D I ++K
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKK 487
Score = 43.2 bits (97), Expect = 0.009
Identities = 24/90 (26%), Positives = 41/90 (45%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F +++ V E V + I G P P++ WY + K + I N + TI
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+A ++ G Y+C A + G T A++ +
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 39.5 bits (88), Expect = 0.12
Identities = 18/51 (35%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
AP K L + + +EG+L+ E + G P P+V W R+GT + S +++I
Sbjct: 434 APVFTKMLQNL-SASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRI 483
Score = 37.5 bits (83), Expect = 0.47
Identities = 17/58 (29%), Positives = 29/58 (50%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
+ P F K + E ++V FE G P+P++ WY++ +I F I K+ R+
Sbjct: 433 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRS 490
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 64.5 bits (150), Expect = 4e-09
Identities = 65/256 (25%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 420 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 479
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 480 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 518
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 519 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 574
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE H E+L AA++ T+
Sbjct: 575 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQ------CHREQLVAAVEVTEQETKV 628
Query: 1526 VKEIIPERVHEEEIVT 1541
K+ + + EE I T
Sbjct: 629 PKKTV---IIEETITT 641
Score = 60.5 bits (140), Expect = 6e-08
Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 10/166 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 483 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 535
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 536 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 595
Query: 1369 ILNIEA--YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
L I++ + E +++ + ++ E P+ + +TT
Sbjct: 596 ELRIQSPMLQAQEQCHREQLVAAVEVTEQETKVPKKTVIIEETITT 641
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 505 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 564
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 565 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 599
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 392 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 451
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 452 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 504
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 64.1 bits (149), Expect = 5e-09
Identities = 60/204 (29%), Positives = 87/204 (42%), Gaps = 30/204 (14%)
Query: 1237 LNVLEENISKDLIGVVTCRAEN-FAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD 1295
L +L S D G+ C A N G+V + G+ V+ + P + P N +++
Sbjct: 84 LTILSVEDSDD--GIYCCTANNGVGGAVESCGALQVKMK-------PKITRPPINVKIIE 134
Query: 1296 GERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C +G P P + W + L E +R I+ +SG IH E AG Y+
Sbjct: 135 GLKAVLPCTTMGNPKPSVSWIKGDSPLRENSR---IAVLESGSLRIH--NVQKEDAGQYR 189
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C A N G AY V + E+ E D + FA RI++A P T
Sbjct: 190 CVAKNSLG----------TAYSKVVKLEVEE--ESEPEQDTKVFA-RILRA-PESHNVTF 235
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQG 1438
G + L A GIP P + W+ G
Sbjct: 236 GSFVTLHCTATGIPVPTITWIENG 259
Score = 57.2 bits (132), Expect = 5e-07
Identities = 82/329 (24%), Positives = 130/329 (39%), Gaps = 49/329 (14%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ PLE + E + C + P P+I W N+ LI+ R+ L I
Sbjct: 27 APVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTI 86
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
E + GIY CTA+N G C A + + P
Sbjct: 87 LSVEDSDD--GIYCCTANNGVGGAVESC----GALQV-------------------KMKP 121
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+I + P V EG L +G PKP V W++ + L +++ +I L+ G+ L
Sbjct: 122 KITRP-PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGS--LR 176
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQ 1520
+ V ++D G+ A N LG TA + +E +E +PE T + L+A +
Sbjct: 177 IHNVQKEDAGQYRCVAKNSLG-TAYSKVVKLE----VEEESEPEQDTKV--FARILRAPE 229
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTC 1580
S V VT +G P P I W ++ + + I E+ ++R
Sbjct: 230 S----------HNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGS--IQESVKDRVID 277
Query: 1581 TIKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
+ + G YTC A + G + AK
Sbjct: 278 SRLQLFITKPGLYTCIATNKHGEKFSTAK 306
Score = 41.5 bits (93), Expect = 0.029
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSI-VEEQTCIDGDAPL---VLAPLENTTVMDGER 1298
N+ K+ G C A+N G+ + + VEE++ + D + +L E+ V G
Sbjct: 179 NVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSF 238
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
++L+C G P P I W N + + I S K + + + + F G+Y C A+
Sbjct: 239 VTLHCTATGIPVPTITWIENGNAVSSG-SIQES-VKDRVIDSRL-QLFITKPGLYTCIAT 295
Query: 1359 NQFGK 1363
N+ G+
Sbjct: 296 NKHGE 300
>BC073969-1|AAH73969.1| 1026|Homo sapiens NEFH protein protein.
Length = 1026
Score = 64.1 bits (149), Expect = 5e-09
Identities = 86/380 (22%), Positives = 147/380 (38%), Gaps = 23/380 (6%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K ++ + + K+ +E K + + E +S + K E K
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEEAK 667
Query: 203 SWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEV 262
S K + E P K + + + K+ E K +EE + E K K E
Sbjct: 668 SPEKAKSPVKAEAKSPEKAKSPVKA----EAKSPEKAKSPVKEEAKSPEKAKSPVKE-EA 722
Query: 263 KDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
K K K P +EA P K KSP+++E K K +D KS E E
Sbjct: 723 KSPEKAKSPVKEEA--KTPEKA-KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 779
Query: 323 ------QITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALKT 375
+ EK +S + +++ EK K L+ KE K + + ++E +
Sbjct: 780 ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP-QE 838
Query: 376 VRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEK 435
V+ P +K+SK+ E K+ KP + +E +P K K
Sbjct: 839 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEE--APKKEAPKPKVEEKKEPAVEKP-KESK 895
Query: 436 TPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKW 495
+KE+ ED PT ++ ++ + A ++ K+E K E + P E+K
Sbjct: 896 VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK- 954
Query: 496 PTGKRQPKEETPQEEVVLKP 515
+ P+++ +EE KP
Sbjct: 955 ---EAAPEKKDTKEEKAKKP 971
Score = 53.2 bits (122), Expect = 9e-06
Identities = 90/381 (23%), Positives = 148/381 (38%), Gaps = 29/381 (7%)
Query: 173 VSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKGVNEPEVCHWRK 232
VSTH +KV++ E + V S K ET +EE EE T+ V E E ++
Sbjct: 432 VSTH-----IKVKSEEKIKVVEKSEK-ETVI-----VEEQTEETQVTEEVTEEEEKEAKE 480
Query: 233 PKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQ-KIPWTQEAIKLRPTKVEKSPIEK 291
+ E + EEE E + +S A E K+ K P +EA P + KSP EK
Sbjct: 481 EEGKEE-EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS--PAEA-KSP-EK 535
Query: 292 EKIEDVALKPVRKDSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNK--LLENIV 349
E+ + A V+ + E ++ E + EK+E+ +++ EK K E
Sbjct: 536 EEAKSPA--EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 350 SEESKESTGKRRQ--REEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETED 407
S +S K + +EE A V+ K T++E+K E
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS--PTKEEAKSPEK 651
Query: 408 RINTKDTRKPSIPWTQEAIKLR-PTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCA 466
+ + + P + K + P K E EK K + + + + EE +
Sbjct: 652 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK-SPVKAEAKSPEKAKSPVKEEAKS 710
Query: 467 LKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQP-KEETPQEEVVLKPTRXXXXXXXX 525
+ A +++E P+K +++ EE K P + P KEE E P +
Sbjct: 711 PEKAKSPVKEEAKSPEK-AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 769
Query: 526 XXXXXXWPSGKRRPKEETPQE 546
R P ++ P++
Sbjct: 770 PEAKTPAKEEARSPADKFPEK 790
Score = 50.4 bits (115), Expect = 6e-05
Identities = 109/480 (22%), Positives = 183/480 (38%), Gaps = 49/480 (10%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
+ H+KV+ + K+ K SEK+ ++ E+T + + E E +
Sbjct: 432 VSTHIKVKSEEKIKVVEK----SEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 203 SWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTKALE 261
+ E EE TK E K S + ++ K+ E + E K+++ E
Sbjct: 488 GGEEEEAEGGEEE---TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE-KEEAKSPAE 543
Query: 262 VKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNE 321
VK K K P +EA K P KSP EKE+ + A V+ + E ++ E
Sbjct: 544 VKSPEKAKSPAKEEA-KSPPE--AKSP-EKEEAKSPA--EVKSPEKAKSPAKEEAKSPAE 597
Query: 322 RQITEK-KESLQETQLQPTE-KNKLLENIVSEESKESTGKRRQ--REEITQKEVALKTVR 377
+ EK K ++E P E K+ + E S +S K + +EE E A +
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 378 XXXXXXXXXXXXXSLKPVLTTEKESKE---TEDRINTKDTRKPSIPWTQEAIKLRPTKME 434
K + E +S E + + K K P +EA + +
Sbjct: 658 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA---KSPEKA 714
Query: 435 KTPIEKE-KFEDITLKPTRKQSLVDE-----ITEEVCALKSALDDIEKEEHKPDKVSENN 488
K+P+++E K + P ++++ E + EE + + A EK + K E
Sbjct: 715 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP-EKAKTLDVKSPEAK 773
Query: 489 AP--EERKWPTGKRQPKEETPQEEVVLKPTRXXXXXXXXXXXXXXWPSGKRRPKEETPQE 546
P EE + P K K ++P +E V P + + P++E P++
Sbjct: 774 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL----------KEDAKAPEKEIPKK 823
Query: 547 EVVLXXXXXXXXXXXXXXXXXXXXXVKKEKQIEDATP--EERKWPSGKRRPKEETPQEEV 604
E V K E++ ATP EE+K + PK+E P+ +V
Sbjct: 824 EEV---KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 880
Score = 37.1 bits (82), Expect = 0.61
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 14/192 (7%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K QEV K+ PK E+K T E + K E + + +
Sbjct: 830 VKEEEKPQEV---KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 886
Query: 203 SWRKPR---LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTK 258
+ KP+ +E EE K V PE P E+ +D K +E+ V + + K
Sbjct: 887 AVEKPKESKVEAKKEEAEDKKKVPTPEK---EAPAKVEVKEDAKPKEKTEVAKKEPDDAK 943
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISEL 318
A E +++K + A + + TK EK+ +EK + A +L E S +E
Sbjct: 944 AKEPSKPAEKK----EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 999
Query: 319 QNERQITEKKES 330
+ T++K+S
Sbjct: 1000 AEKSSSTDQKDS 1011
Score = 35.5 bits (78), Expect = 1.9
Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 15/159 (9%)
Query: 752 EERKWPSGKRRPKEE---TPQKEV-LLEHVXXXXXXXXXXXXXNVLKDVSETEKESKERG 807
EE K P + P +E P+KE+ E V V + + E+E
Sbjct: 797 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 856
Query: 808 DKIQTK-DTRKSSIPWTQEAIKLRPTKKRFYVRRKTRRSYTLRALVDKIHTEEQELKDKE 866
K + K D++K P +EA K + +K+ K + S K+ +++E +DK+
Sbjct: 857 PKTEEKKDSKKEEAP-KKEAPKPKVEEKKEPAVEKPKES--------KVEAKKEEAEDKK 907
Query: 867 RVQEIRDEQMKTDKPVEDAMPEERKWPTGKRRPKEATSQ 905
+V E + EDA P+E K K+ P +A ++
Sbjct: 908 KVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAK 945
>AF203032-1|AAF13722.1| 1026|Homo sapiens neurofilament protein
protein.
Length = 1026
Score = 64.1 bits (149), Expect = 5e-09
Identities = 86/380 (22%), Positives = 147/380 (38%), Gaps = 23/380 (6%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K ++ + + K+ +E K + + E +S + K E K
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEEAK 667
Query: 203 SWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEV 262
S K + E P K + + + K+ E K +EE + E K K E
Sbjct: 668 SPEKAKSPVKAEAKSPEKAKSPVKA----EAKSPEKAKSPVKEEAKSPEKAKSPVKE-EA 722
Query: 263 KDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
K K K P +EA P K KSP+++E K K +D KS E E
Sbjct: 723 KSPEKAKSPVKEEA--KTPEKA-KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 779
Query: 323 ------QITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALKT 375
+ EK +S + +++ EK K L+ KE K + + ++E +
Sbjct: 780 ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP-QE 838
Query: 376 VRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEK 435
V+ P +K+SK+ E K+ KP + +E +P K K
Sbjct: 839 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEE--APKKEAPKPKVEEKKEPAVEKP-KESK 895
Query: 436 TPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKW 495
+KE+ ED PT ++ ++ + A ++ K+E K E + P E+K
Sbjct: 896 VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK- 954
Query: 496 PTGKRQPKEETPQEEVVLKP 515
+ P+++ +EE KP
Sbjct: 955 ---EAAPEKKDTKEEKAKKP 971
Score = 53.2 bits (122), Expect = 9e-06
Identities = 90/381 (23%), Positives = 148/381 (38%), Gaps = 29/381 (7%)
Query: 173 VSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKGVNEPEVCHWRK 232
VSTH +KV++ E + V S K ET +EE EE T+ V E E ++
Sbjct: 432 VSTH-----IKVKSEEKIKVVEKSEK-ETVI-----VEEQTEETQVTEEVTEEEEKEAKE 480
Query: 233 PKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQ-KIPWTQEAIKLRPTKVEKSPIEK 291
+ E + EEE E + +S A E K+ K P +EA P + KSP EK
Sbjct: 481 EEGKEE-EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS--PAEA-KSP-EK 535
Query: 292 EKIEDVALKPVRKDSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNK--LLENIV 349
E+ + A V+ + E ++ E + EK+E+ +++ EK K E
Sbjct: 536 EEAKSPA--EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 350 SEESKESTGKRRQ--REEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETED 407
S +S K + +EE A V+ K T++E+K E
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS--PTKEEAKSPEK 651
Query: 408 RINTKDTRKPSIPWTQEAIKLR-PTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCA 466
+ + + P + K + P K E EK K + + + + EE +
Sbjct: 652 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK-SPVKAEAKSPEKAKSPVKEEAKS 710
Query: 467 LKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQP-KEETPQEEVVLKPTRXXXXXXXX 525
+ A +++E P+K +++ EE K P + P KEE E P +
Sbjct: 711 PEKAKSPVKEEAKSPEK-AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 769
Query: 526 XXXXXXWPSGKRRPKEETPQE 546
R P ++ P++
Sbjct: 770 PEAKTPAKEEARSPADKFPEK 790
Score = 50.4 bits (115), Expect = 6e-05
Identities = 109/480 (22%), Positives = 183/480 (38%), Gaps = 49/480 (10%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
+ H+KV+ + K+ K SEK+ ++ E+T + + E E +
Sbjct: 432 VSTHIKVKSEEKIKVVEK----SEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 203 SWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTKALE 261
+ E EE TK E K S + ++ K+ E + E K+++ E
Sbjct: 488 GGEEEEAEGGEEE---TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE-KEEAKSPAE 543
Query: 262 VKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNE 321
VK K K P +EA K P KSP EKE+ + A V+ + E ++ E
Sbjct: 544 VKSPEKAKSPAKEEA-KSPPE--AKSP-EKEEAKSPA--EVKSPEKAKSPAKEEAKSPAE 597
Query: 322 RQITEK-KESLQETQLQPTE-KNKLLENIVSEESKESTGKRRQ--REEITQKEVALKTVR 377
+ EK K ++E P E K+ + E S +S K + +EE E A +
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 378 XXXXXXXXXXXXXSLKPVLTTEKESKE---TEDRINTKDTRKPSIPWTQEAIKLRPTKME 434
K + E +S E + + K K P +EA + +
Sbjct: 658 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA---KSPEKA 714
Query: 435 KTPIEKE-KFEDITLKPTRKQSLVDE-----ITEEVCALKSALDDIEKEEHKPDKVSENN 488
K+P+++E K + P ++++ E + EE + + A EK + K E
Sbjct: 715 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP-EKAKTLDVKSPEAK 773
Query: 489 AP--EERKWPTGKRQPKEETPQEEVVLKPTRXXXXXXXXXXXXXXWPSGKRRPKEETPQE 546
P EE + P K K ++P +E V P + + P++E P++
Sbjct: 774 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL----------KEDAKAPEKEIPKK 823
Query: 547 EVVLXXXXXXXXXXXXXXXXXXXXXVKKEKQIEDATP--EERKWPSGKRRPKEETPQEEV 604
E V K E++ ATP EE+K + PK+E P+ +V
Sbjct: 824 EEV---KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 880
Score = 37.1 bits (82), Expect = 0.61
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 14/192 (7%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K QEV K+ PK E+K T E + K E + + +
Sbjct: 830 VKEEEKPQEV---KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 886
Query: 203 SWRKPR---LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTK 258
+ KP+ +E EE K V PE P E+ +D K +E+ V + + K
Sbjct: 887 AVEKPKESKVEAKKEEAEDKKKVPTPEK---EAPAKVEVKEDAKPKEKTEVAKKEPDDAK 943
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISEL 318
A E +++K + A + + TK EK+ +EK + A +L E S +E
Sbjct: 944 AKEPSKPAEKK----EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 999
Query: 319 QNERQITEKKES 330
+ T++K+S
Sbjct: 1000 AEKSSSTDQKDS 1011
Score = 35.5 bits (78), Expect = 1.9
Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 15/159 (9%)
Query: 752 EERKWPSGKRRPKEE---TPQKEV-LLEHVXXXXXXXXXXXXXNVLKDVSETEKESKERG 807
EE K P + P +E P+KE+ E V V + + E+E
Sbjct: 797 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 856
Query: 808 DKIQTK-DTRKSSIPWTQEAIKLRPTKKRFYVRRKTRRSYTLRALVDKIHTEEQELKDKE 866
K + K D++K P +EA K + +K+ K + S K+ +++E +DK+
Sbjct: 857 PKTEEKKDSKKEEAP-KKEAPKPKVEEKKEPAVEKPKES--------KVEAKKEEAEDKK 907
Query: 867 RVQEIRDEQMKTDKPVEDAMPEERKWPTGKRRPKEATSQ 905
+V E + EDA P+E K K+ P +A ++
Sbjct: 908 KVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAK 945
>AB020652-1|BAA74868.2| 1034|Homo sapiens KIAA0845 protein protein.
Length = 1034
Score = 64.1 bits (149), Expect = 5e-09
Identities = 86/380 (22%), Positives = 147/380 (38%), Gaps = 23/380 (6%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K ++ + + K+ +E K + + E +S + K E K
Sbjct: 616 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKAKSPEKEEAK 675
Query: 203 SWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEV 262
S K + E P K + + + K+ E K +EE + E K K E
Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKA----EAKSPEKAKSPVKEEAKSPEKAKSPVKE-EA 730
Query: 263 KDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
K K K P +EA P K KSP+++E K K +D KS E E
Sbjct: 731 KSPEKAKSPVKEEA--KTPEKA-KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 787
Query: 323 ------QITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALKT 375
+ EK +S + +++ EK K L+ KE K + + ++E +
Sbjct: 788 ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP-QE 846
Query: 376 VRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEK 435
V+ P +K+SK+ E K+ KP + +E +P K K
Sbjct: 847 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEE--APKKEAPKPKVEEKKEPAVEKP-KESK 903
Query: 436 TPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKW 495
+KE+ ED PT ++ ++ + A ++ K+E K E + P E+K
Sbjct: 904 VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK- 962
Query: 496 PTGKRQPKEETPQEEVVLKP 515
+ P+++ +EE KP
Sbjct: 963 ---EAAPEKKDTKEEKAKKP 979
Score = 53.2 bits (122), Expect = 9e-06
Identities = 90/381 (23%), Positives = 148/381 (38%), Gaps = 29/381 (7%)
Query: 173 VSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKGVNEPEVCHWRK 232
VSTH +KV++ E + V S K ET +EE EE T+ V E E ++
Sbjct: 440 VSTH-----IKVKSEEKIKVVEKSEK-ETVI-----VEEQTEETQVTEEVTEEEEKEAKE 488
Query: 233 PKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQ-KIPWTQEAIKLRPTKVEKSPIEK 291
+ E + EEE E + +S A E K+ K P +EA P + KSP EK
Sbjct: 489 EEGKEE-EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS--PAEA-KSP-EK 543
Query: 292 EKIEDVALKPVRKDSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNK--LLENIV 349
E+ + A V+ + E ++ E + EK+E+ +++ EK K E
Sbjct: 544 EEAKSPA--EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 601
Query: 350 SEESKESTGKRRQ--REEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETED 407
S +S K + +EE A V+ K T++E+K E
Sbjct: 602 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS--PTKEEAKSPEK 659
Query: 408 RINTKDTRKPSIPWTQEAIKLR-PTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCA 466
+ + + P + K + P K E EK K + + + + EE +
Sbjct: 660 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK-SPVKAEAKSPEKAKSPVKEEAKS 718
Query: 467 LKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQP-KEETPQEEVVLKPTRXXXXXXXX 525
+ A +++E P+K +++ EE K P + P KEE E P +
Sbjct: 719 PEKAKSPVKEEAKSPEK-AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 777
Query: 526 XXXXXXWPSGKRRPKEETPQE 546
R P ++ P++
Sbjct: 778 PEAKTPAKEEARSPADKFPEK 798
Score = 50.4 bits (115), Expect = 6e-05
Identities = 109/480 (22%), Positives = 183/480 (38%), Gaps = 49/480 (10%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
+ H+KV+ + K+ K SEK+ ++ E+T + + E E +
Sbjct: 440 VSTHIKVKSEEKIKVVEK----SEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 495
Query: 203 SWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTKALE 261
+ E EE TK E K S + ++ K+ E + E K+++ E
Sbjct: 496 GGEEEEAEGGEEE---TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE-KEEAKSPAE 551
Query: 262 VKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNE 321
VK K K P +EA K P KSP EKE+ + A V+ + E ++ E
Sbjct: 552 VKSPEKAKSPAKEEA-KSPPE--AKSP-EKEEAKSPA--EVKSPEKAKSPAKEEAKSPAE 605
Query: 322 RQITEK-KESLQETQLQPTE-KNKLLENIVSEESKESTGKRRQ--REEITQKEVALKTVR 377
+ EK K ++E P E K+ + E S +S K + +EE E A +
Sbjct: 606 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 665
Query: 378 XXXXXXXXXXXXXSLKPVLTTEKESKE---TEDRINTKDTRKPSIPWTQEAIKLRPTKME 434
K + E +S E + + K K P +EA + +
Sbjct: 666 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA---KSPEKA 722
Query: 435 KTPIEKE-KFEDITLKPTRKQSLVDE-----ITEEVCALKSALDDIEKEEHKPDKVSENN 488
K+P+++E K + P ++++ E + EE + + A EK + K E
Sbjct: 723 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP-EKAKTLDVKSPEAK 781
Query: 489 AP--EERKWPTGKRQPKEETPQEEVVLKPTRXXXXXXXXXXXXXXWPSGKRRPKEETPQE 546
P EE + P K K ++P +E V P + + P++E P++
Sbjct: 782 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL----------KEDAKAPEKEIPKK 831
Query: 547 EVVLXXXXXXXXXXXXXXXXXXXXXVKKEKQIEDATP--EERKWPSGKRRPKEETPQEEV 604
E V K E++ ATP EE+K + PK+E P+ +V
Sbjct: 832 EEV---KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 888
Score = 37.1 bits (82), Expect = 0.61
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 14/192 (7%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETK 202
++E K QEV K+ PK E+K T E + K E + + +
Sbjct: 838 VKEEEKPQEV---KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 894
Query: 203 SWRKPR---LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKD-KNEEEIRVQEMKKQSTK 258
+ KP+ +E EE K V PE P E+ +D K +E+ V + + K
Sbjct: 895 AVEKPKESKVEAKKEEAEDKKKVPTPEK---EAPAKVEVKEDAKPKEKTEVAKKEPDDAK 951
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISEL 318
A E +++K + A + + TK EK+ +EK + A +L E S +E
Sbjct: 952 AKEPSKPAEKK----EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 1007
Query: 319 QNERQITEKKES 330
+ T++K+S
Sbjct: 1008 AEKSSSTDQKDS 1019
Score = 35.5 bits (78), Expect = 1.9
Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 15/159 (9%)
Query: 752 EERKWPSGKRRPKEE---TPQKEV-LLEHVXXXXXXXXXXXXXNVLKDVSETEKESKERG 807
EE K P + P +E P+KE+ E V V + + E+E
Sbjct: 805 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT 864
Query: 808 DKIQTK-DTRKSSIPWTQEAIKLRPTKKRFYVRRKTRRSYTLRALVDKIHTEEQELKDKE 866
K + K D++K P +EA K + +K+ K + S K+ +++E +DK+
Sbjct: 865 PKTEEKKDSKKEEAP-KKEAPKPKVEEKKEPAVEKPKES--------KVEAKKEEAEDKK 915
Query: 867 RVQEIRDEQMKTDKPVEDAMPEERKWPTGKRRPKEATSQ 905
+V E + EDA P+E K K+ P +A ++
Sbjct: 916 KVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAK 953
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 63.7 bits (148), Expect = 6e-09
Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 4/185 (2%)
Query: 1431 QVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALS 1490
QV W +L S +Y+I +DG +IL + ++ + D G + N G ++ A L
Sbjct: 2826 QVTWYFGVRQLENSEKYEIT-YEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELF 2884
Query: 1491 VESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNP 1550
V+ + +Y + ++ ++ + P F + + + E V F + +P
Sbjct: 2885 VKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 2944
Query: 1551 TPEILWYKDNKVIR---TDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
P + WYK + I+ D+++ E+ + TI T D + YT A + G K
Sbjct: 2945 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 3004
Query: 1608 AKLQV 1612
AKL V
Sbjct: 3005 AKLTV 3009
Score = 60.9 bits (141), Expect = 4e-08
Identities = 54/197 (27%), Positives = 88/197 (44%), Gaps = 27/197 (13%)
Query: 1391 KTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
KT AP I K + V TT G+ +L + +G P P ++W R G EL+QS +Y++
Sbjct: 1751 KTKLTSGEAPGIRKEMKDV-TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 1809
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME 1510
D T LT+ Q+D G A N +G T + L +++ T ++ P + E
Sbjct: 1810 S-DGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---TPQFH-PGYPL-KE 1863
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFI 1570
+ A+ +T R+H +Y G P P + W+ K+++ E
Sbjct: 1864 KYYGAVGSTL------------RLH--------VMYIGRPVPAMTWFHGQKLLQNSENIT 1903
Query: 1571 IENKENRTTCTIKKATK 1587
IEN E+ T +K +
Sbjct: 1904 IENTEHYTHLVMKNVQR 1920
Score = 60.1 bits (139), Expect = 8e-08
Identities = 63/232 (27%), Positives = 97/232 (41%), Gaps = 29/232 (12%)
Query: 1381 VSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTE 1440
V EE + + + +V A +KA T ++ EG+ + L+A G V+W+ G E
Sbjct: 4248 VHEEITKTSQASEEVRTHAE--IKAFSTQMSINEGQRLVLKANIAGAT--DVKWVLNGVE 4303
Query: 1441 LLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEY 1500
L S EY+ + LT+ + D G + T + + E IV Q Y
Sbjct: 4304 LTNSEEYRYG-VSGSDQTLTIKQASHRDEGIL------------TCISKTKEGIVKCQ-Y 4349
Query: 1501 RKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
+T +EL A P F+ + + ++E + V F SG P+PEI W+K+N
Sbjct: 4350 D----LTLSKELSDA-------PAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNN 4398
Query: 1561 KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I I N + I+ A+ G YT KA + G A L V
Sbjct: 4399 LPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 4450
Score = 58.8 bits (136), Expect = 2e-07
Identities = 70/326 (21%), Positives = 127/326 (38%), Gaps = 24/326 (7%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + L + KL + ++ + +V W + G +L ++ +Q DGT L
Sbjct: 3945 PKITQFLKAEASKEIAKLTCVVESSV-LRAKEVTWYKDGKKLKENGHFQFHYSADGTYEL 4003
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATI------AALSV-ESIVGTQEYRKPEW------V 1506
+ + + D GE V E G + T A S+ E + E +K + V
Sbjct: 4004 KINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTV 4063
Query: 1507 THMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD 1566
T E +A + S P V + V + + F +G P P +W KD K I
Sbjct: 4064 TRKTEPKAP-EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 4122
Query: 1567 ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQRXXXXXXXXXXX 1626
++ + + I K G YTC + G + KL +
Sbjct: 4123 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI----KAIKDTEAQK 4178
Query: 1627 XXXXXXXXXXXEEESVGVEDTLDFATVSEVQALDKQHSTDK--VKKRKAKIVVSESEHIE 1684
++++V E+ A SE + + S +K +K+ +K+++SE E +
Sbjct: 4179 VSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISE-EVKK 4237
Query: 1685 TEDIALQKKV--DEKTKGIPVEEKAK 1708
+ +L+K + +E TK E+ +
Sbjct: 4238 SAATSLEKSIVHEEITKTSQASEEVR 4263
Score = 55.6 bits (128), Expect = 2e-06
Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 27/239 (11%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDW 1315
AEN G +++ + G+AP + +++ T GE L+C+I+GRP P I W
Sbjct: 1734 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 1793
Query: 1316 FH-NEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
+ ++LI++ + S ++ + +E E G+Y C A+N+ G+ T L ++A
Sbjct: 1794 YRFGKELIQSRKYKMSSDGRTHTLTVMTEE--QEDEGVYTCIATNEVGEVETSSKLLLQA 1851
Query: 1375 YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRW 1434
P L ++ V G +RL IG P P + W
Sbjct: 1852 ---TPQFHPGYPLKEKYYGAV-------------------GSTLRLHVMYIGRPVPAMTW 1889
Query: 1435 LRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
G +LLQ++E IE + T ++ + G+ + N G I + ++
Sbjct: 1890 F-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 1947
Score = 55.6 bits (128), Expect = 2e-06
Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
GV TC A N G V TS +++ PL E G + L+ +GRP
Sbjct: 1828 GVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK----EKYYGAVGSTLRLHVMYIGRP 1883
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + WFH +KL++ + +ITI + + AG YK SN FG + + I
Sbjct: 1884 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAI 1941
Query: 1370 LNIE 1373
L++E
Sbjct: 1942 LDVE 1945
Score = 54.8 bits (126), Expect = 3e-06
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 4/123 (3%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G++TC ++ G V + ++ DAP ++ + + +G+ + +I G P
Sbjct: 4332 GILTCISKTKEGIVKCQYDLTLSKEL---SDAPAFISQPRSQNINEGQNVLFTREISGEP 4388
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P+I+WF N I + +++ISR ++ + + I+ A +G Y A N G+CS
Sbjct: 4389 SPEIEWFKNNLPISISSNVSISRSRN-VYSLEIRNASVSDSGKYTIKAKNFRGQCSATAS 4447
Query: 1370 LNI 1372
L +
Sbjct: 4448 LMV 4450
Score = 52.4 bits (120), Expect = 2e-05
Identities = 56/243 (23%), Positives = 96/243 (39%), Gaps = 24/243 (9%)
Query: 1255 RAENFAGSVSTSG-SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKI 1313
+ EN G S S + ++ + AP L N V +L CK+ G P P +
Sbjct: 2127 KCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIV 2186
Query: 1314 DWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
W+ K +I I K G ++ I + A +Y+ A+NQ G S L +
Sbjct: 2187 KWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
E VP+ + P+ ++ + V G+++ ++ G P P +
Sbjct: 2247 E----VPA---------------KIHLPKTLEGM-GAVHALRGEVVSIKIPFSGKPDPVI 2286
Query: 1433 RWLRQGTELLQST-EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W ++G +L+ + YQ+ TS++ V + D G V A N G+ L V
Sbjct: 2287 TW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 2345
Query: 1492 ESI 1494
+
Sbjct: 2346 ADV 2348
Score = 52.0 bits (119), Expect = 2e-05
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 7/115 (6%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG-LCEI 1340
P+++ L++TTV K G P P W + K I +S K G EI
Sbjct: 4079 PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI 4138
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
H + +G+Y CT N G S+ C L I+A + +E +S +KTS++
Sbjct: 4139 HKTDT--SDSGLYTCTVKNSAGSVSSSCKLTIKAIK----DTEAQKVSTQKTSEI 4187
Score = 50.8 bits (116), Expect = 5e-05
Identities = 65/278 (23%), Positives = 112/278 (40%), Gaps = 35/278 (12%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA---RDITISRQKSGLC 1338
P PL N T GE + I P P + W+ + + I+ + T K GL
Sbjct: 2917 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 2975
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
++ I + Y A N++G+ S + L + + P ++ +
Sbjct: 2976 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH---PPPTDSTLRP---------- 3022
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS- 1457
+ K L EG+ + E + GIP P ++W + G L S IE + +G
Sbjct: 3023 ---MFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPL--SLGPNIEIIHEGLDY 3077
Query: 1458 -ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI-VGTQEYR-KPEWVTHMEE--- 1511
L + + +DTG A N G T+ A L VE + QE++ K E H+++
Sbjct: 3078 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQID 3137
Query: 1512 ----LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAI 1545
+ L T+SVP + ++ E + E ++ A+
Sbjct: 3138 KTLRMAEILSGTESVP--LTQVAKEALREAAVLYKPAV 3173
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 8/105 (7%)
Query: 1506 VTHMEELQAA----LKA-TQSVPTFVKEIIPE-RVHEEEIVTFEAIYSGNPTPEILWYKD 1559
+++M +L+++ LKA + +P ++ + + + E +++T ++G PTPE+ W
Sbjct: 4533 ISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCG 4592
Query: 1560 NKVIRTDE--RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+ I + E RF IEN ++ TT I K G YT ++ G
Sbjct: 4593 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 4637
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL--LQSTEYQIEELDDGTS 1457
P ++ALP+ ++ EGK++ + G P P+V W G ++ + + IE DD T+
Sbjct: 4555 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 4614
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
++ M +V + D G N G + + + SI
Sbjct: 4615 LIIM-DVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 4650
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/63 (30%), Positives = 33/63 (52%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+I WY+ K + ++ + + T T+ ++ EG YTC A +++G T
Sbjct: 1785 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 1844
Query: 1608 AKL 1610
+KL
Sbjct: 1845 SKL 1847
Score = 41.1 bits (92), Expect = 0.038
Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
EY S++E + + + D+E + L VT G +RL G P P + W
Sbjct: 654 EYSESIAEIEPVERIEIPDLE-----LADDLKKTVTIRAGASLRLMVSVSGRPPPVITWS 708
Query: 1436 RQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIV 1495
+QG +L I + + S+L + +V + D G+ EA N G + + V
Sbjct: 709 KQGIDLASRA---IIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTP 765
Query: 1496 G 1496
G
Sbjct: 766 G 766
Score = 39.9 bits (89), Expect = 0.087
Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 2/120 (1%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
+++ D V RA N GSVS + S VE I P L + + GE +S+
Sbjct: 2218 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH--LPKTLEGMGAVHALRGEVVSIK 2275
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
G+P P I W + LI+ + +S + + AG Y A N+FG
Sbjct: 2276 IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 2335
Score = 39.1 bits (87), Expect = 0.15
Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 16/195 (8%)
Query: 1366 TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL-------PTVVTTTEGKLI 1418
TE ++ +YE+ S + +EK+ + + +I L P +T EG+
Sbjct: 3746 TETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESA 3805
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
R G P P V WLR+G L S +Q+ S + V D G N
Sbjct: 3806 RFSCDTDGEPVPTVTWLRKGRVLSTSARHQV-TTTKYKSTFEISSVQASDEGNYSVVVEN 3864
Query: 1479 HLGVTATIAALSVESIVGTQE-YRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
G L+++ T++ P V E + +A +S P VK PE H +
Sbjct: 3865 SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKS-PKRVKS--PEPSHPK 3921
Query: 1538 EIVTFEAIYSGNPTP 1552
+ E PTP
Sbjct: 3922 AVSPTET----KPTP 3932
Score = 39.1 bits (87), Expect = 0.15
Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA--RDITISRQKSGLC 1338
A +L + TV +GE +C G P P + W +++ T+ +T ++ KS
Sbjct: 3787 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTF- 3845
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
EI +A E G Y N GK E L I+
Sbjct: 3846 EISSVQASDE--GNYSVVVENSEGKQEAEFTLTIQ 3878
Score = 37.5 bits (83), Expect = 0.47
Identities = 21/114 (18%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDIT 1329
++ +Q AP + + + V G+ + +P ++ W+HN ++ + I
Sbjct: 3589 VLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH 3648
Query: 1330 ISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE 1383
+ SG+ + I + + +G Y+ +N G+ S L++ +Y S+
Sbjct: 3649 YTNT-SGVLTLEILDCHTDDSGTYRAVCTNYKGERSDYATLDVTGGDYTTYASQ 3701
Score = 35.9 bits (79), Expect = 1.4
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ +A G P P+I+W K +K + E+ ++ R T IK + G YT +
Sbjct: 292 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 351
Query: 1600 DIGLAVTKAKLQV 1612
G ++V
Sbjct: 352 ASGTKAVSVMVKV 364
Score = 35.5 bits (78), Expect = 1.9
Identities = 16/61 (26%), Positives = 26/61 (42%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V+E E F G P P + W + +V+ T R + + ++T I EG Y
Sbjct: 3799 VYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNY 3858
Query: 1594 T 1594
+
Sbjct: 3859 S 3859
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 63.7 bits (148), Expect = 6e-09
Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 4/185 (2%)
Query: 1431 QVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALS 1490
QV W +L S +Y+I +DG +IL + ++ + D G + N G ++ A L
Sbjct: 2826 QVTWYFGVRQLENSEKYEIT-YEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELF 2884
Query: 1491 VESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNP 1550
V+ + +Y + ++ ++ + P F + + + E V F + +P
Sbjct: 2885 VKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP 2944
Query: 1551 TPEILWYKDNKVIR---TDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
P + WYK + I+ D+++ E+ + TI T D + YT A + G K
Sbjct: 2945 EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 3004
Query: 1608 AKLQV 1612
AKL V
Sbjct: 3005 AKLTV 3009
Score = 60.9 bits (141), Expect = 4e-08
Identities = 54/197 (27%), Positives = 88/197 (44%), Gaps = 27/197 (13%)
Query: 1391 KTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
KT AP I K + V TT G+ +L + +G P P ++W R G EL+QS +Y++
Sbjct: 1751 KTKLTSGEAPGIRKEMKDV-TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS 1809
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME 1510
D T LT+ Q+D G A N +G T + L +++ T ++ P + E
Sbjct: 1810 S-DGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---TPQFH-PGYPL-KE 1863
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFI 1570
+ A+ +T R+H +Y G P P + W+ K+++ E
Sbjct: 1864 KYYGAVGSTL------------RLH--------VMYIGRPVPAMTWFHGQKLLQNSENIT 1903
Query: 1571 IENKENRTTCTIKKATK 1587
IEN E+ T +K +
Sbjct: 1904 IENTEHYTHLVMKNVQR 1920
Score = 55.6 bits (128), Expect = 2e-06
Identities = 56/239 (23%), Positives = 100/239 (41%), Gaps = 27/239 (11%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDW 1315
AEN G +++ + G+AP + +++ T GE L+C+I+GRP P I W
Sbjct: 1734 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 1793
Query: 1316 FH-NEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
+ ++LI++ + S ++ + +E E G+Y C A+N+ G+ T L ++A
Sbjct: 1794 YRFGKELIQSRKYKMSSDGRTHTLTVMTEE--QEDEGVYTCIATNEVGEVETSSKLLLQA 1851
Query: 1375 YEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRW 1434
P L ++ V G +RL IG P P + W
Sbjct: 1852 ---TPQFHPGYPLKEKYYGAV-------------------GSTLRLHVMYIGRPVPAMTW 1889
Query: 1435 LRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
G +LLQ++E IE + T ++ + G+ + N G I + ++
Sbjct: 1890 F-HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 1947
Score = 55.6 bits (128), Expect = 2e-06
Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 6/124 (4%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
GV TC A N G V TS +++ PL E G + L+ +GRP
Sbjct: 1828 GVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLK----EKYYGAVGSTLRLHVMYIGRP 1883
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + WFH +KL++ + +ITI + + AG YK SN FG + + I
Sbjct: 1884 VPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG--TVDAI 1941
Query: 1370 LNIE 1373
L++E
Sbjct: 1942 LDVE 1945
Score = 52.4 bits (120), Expect = 2e-05
Identities = 56/243 (23%), Positives = 96/243 (39%), Gaps = 24/243 (9%)
Query: 1255 RAENFAGSVSTSG-SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKI 1313
+ EN G S S + ++ + AP L N V +L CK+ G P P +
Sbjct: 2127 KCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIV 2186
Query: 1314 DWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
W+ K +I I K G ++ I + A +Y+ A+NQ G S L +
Sbjct: 2187 KWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
E VP+ + P+ ++ + V G+++ ++ G P P +
Sbjct: 2247 E----VPA---------------KIHLPKTLEGM-GAVHALRGEVVSIKIPFSGKPDPVI 2286
Query: 1433 RWLRQGTELLQST-EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W ++G +L+ + YQ+ TS++ V + D G V A N G+ L V
Sbjct: 2287 TW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 2345
Query: 1492 ESI 1494
+
Sbjct: 2346 ADV 2348
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/63 (30%), Positives = 33/63 (52%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+I WY+ K + ++ + + T T+ ++ EG YTC A +++G T
Sbjct: 1785 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 1844
Query: 1608 AKL 1610
+KL
Sbjct: 1845 SKL 1847
Score = 41.5 bits (93), Expect = 0.029
Identities = 19/78 (24%), Positives = 36/78 (46%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P+ L N +G+ + ++ G P P + W + + + +I I + +H
Sbjct: 3022 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 3081
Query: 1342 IKEAFPEMAGIYKCTASN 1359
I++ PE G Y+ TA+N
Sbjct: 3082 IRDTLPEDTGYYRVTATN 3099
Score = 41.1 bits (92), Expect = 0.038
Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
Query: 1376 EYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWL 1435
EY S++E + + + D+E + L VT G +RL G P P + W
Sbjct: 654 EYSESIAEIEPVERIEIPDLE-----LADDLKKTVTIRAGASLRLMVSVSGRPPPVITWS 708
Query: 1436 RQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIV 1495
+QG +L I + + S+L + +V + D G+ EA N G + + V
Sbjct: 709 KQGIDLASRA---IIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTP 765
Query: 1496 G 1496
G
Sbjct: 766 G 766
Score = 39.9 bits (89), Expect = 0.087
Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 2/120 (1%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
+++ D V RA N GSVS + S VE I P L + + GE +S+
Sbjct: 2218 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH--LPKTLEGMGAVHALRGEVVSIK 2275
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
G+P P I W + LI+ + +S + + AG Y A N+FG
Sbjct: 2276 IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 2335
Score = 35.9 bits (79), Expect = 1.4
Identities = 18/73 (24%), Positives = 31/73 (42%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ +A G P P+I+W K +K + E+ ++ R T IK + G YT +
Sbjct: 292 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 351
Query: 1600 DIGLAVTKAKLQV 1612
G ++V
Sbjct: 352 ASGTKAVSVMVKV 364
>BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein
protein.
Length = 143
Score = 63.7 bits (148), Expect = 6e-09
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
++E S+D G+ TC A N AG S S +V + P+ + L+NT V DG
Sbjct: 7 IIEPVTSRDA-GIYTCIATNRAGQNSFSLELVVAAKEA--HKPPVFIEKLQNTGVADGYP 63
Query: 1299 ISLNCKILGRPWPKIDW-FHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L C++LG P P+I W NE L + +++ + G + I+ A E AG Y +A
Sbjct: 64 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 123
Query: 1358 SNQFGKCSTECILNIEAY 1375
N+ G S C ++ Y
Sbjct: 124 KNEAGIVS--CTARLDVY 139
Score = 48.0 bits (109), Expect = 3e-04
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI--RTDER 1568
EL A K P F++++ V + V E G P P+I W K+N+ + TD
Sbjct: 35 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV 94
Query: 1569 FIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
+ ++ I+ ATK+ G YT A ++ G+ A+L V+
Sbjct: 95 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 139
Score = 44.4 bits (100), Expect = 0.004
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDTGEI 1472
+G +RLE + +G+P PQ+ W ++ L ST+ + + + G L + ++D G
Sbjct: 60 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 119
Query: 1473 VFEAYNHLGVTATIAALSV 1491
A N G+ + A L V
Sbjct: 120 TVSAKNEAGIVSCTARLDV 138
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 63.7 bits (148), Expect = 6e-09
Identities = 61/202 (30%), Positives = 88/202 (43%), Gaps = 30/202 (14%)
Query: 1282 PLVLAPL-ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P V+ P EN TV+ ISL C++ G P P + W NE+ I+ + I G +
Sbjct: 2 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRTL 58
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYV-PSVSEEDVLSDEKTSDVEEFA 1399
I A G Y C A NQ G+ + L + YV PS+ + D E S
Sbjct: 59 QIIRAKVSDGGEYTCIAINQAGESKKKFSLTV----YVPPSIKDHD---SESLS------ 105
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
VV EG + LE ++ +P P + W + G + +ST +E L DG +L
Sbjct: 106 ---------VVNVREGTSVSLEXESNAVPPPVITWYKNGRMITEST--HVEILADG-QML 153
Query: 1460 TMPEVYQDDTGEIVFEAYNHLG 1481
+ + DTG+ V A N G
Sbjct: 154 HIKKAEVSDTGQYVCRAINVAG 175
Score = 60.5 bits (140), Expect = 6e-08
Identities = 97/369 (26%), Positives = 133/369 (36%), Gaps = 61/369 (16%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI-DGDAPLVLAPLENTTV 1293
+ L ++ +S G TC A N AG S V I D D+ L V
Sbjct: 56 RTLQIIRAKVSDG--GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSE----SLSVVNV 109
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
+G +SL + P P I W+ N ++I + + I L HIK+A G Y
Sbjct: 110 REGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQML---HIKKAEVSDTGQY 166
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
C A N G+ LN+ YVP P I V+ T
Sbjct: 167 VCRAINVAGRDDKNFHLNV----YVP--------------------PSIEGPEREVIVET 202
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L A GIP P + WL+ + S ++ L G S L + D+G
Sbjct: 203 ISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKLQIARSQHSDSGNYT 261
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N G LS++ P V E +P+ V ++ E
Sbjct: 262 CIASNMEGKAQKYYFLSIQ---------VPPSVAGAE-----------IPSDVSVLLGEN 301
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
V E+V +G PTP I W KD K I + E I N +T I A G Y
Sbjct: 302 V---ELV---CNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 355
Query: 1594 TCKAVSDIG 1602
TC A + G
Sbjct: 356 TCVATNPAG 364
Score = 60.1 bits (139), Expect = 8e-08
Identities = 65/243 (26%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDG-DAPLVLAPLENTTVMDGERISLNCKILGR 1308
G CRA N AG + V I+G + +++ + N ++L C G
Sbjct: 164 GQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGI 216
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W N K IE + + + R SG ++ I + +G Y C ASN GK
Sbjct: 217 PPPTIAWLKNHKRIENSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 275
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
L+I+ PSV+ ++ SD V+ G+ + L A GIP
Sbjct: 276 FLSIQV---PPSVAGAEIPSD--------------------VSVLLGENVELVCNANGIP 312
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++WL+ G + +I +G S L + DTG+ A N G I
Sbjct: 313 TPLIQWLKDGKPIASGETERIRVSANG-STLNIYGALTSDTGKYTCVATNPAGEEDRIFN 371
Query: 1489 LSV 1491
L+V
Sbjct: 372 LNV 374
Score = 59.3 bits (137), Expect = 1e-07
Identities = 64/241 (26%), Positives = 97/241 (40%), Gaps = 41/241 (17%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPL-VLAPLENTTVMDGERIS 1300
E +SK+ G C AEN G V G V+E GD P + PL G
Sbjct: 1354 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWIEPL-------GGNAI 1406
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
LNC++ G P P I W N K ++ +I+ ++ G + I E AG Y C A+N+
Sbjct: 1407 LNCEVKGDPTPTIQW--NRKGVDI--EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNE 1462
Query: 1361 FGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRL 1420
G L ++ +P I+ P G I L
Sbjct: 1463 AGVVERSMSLTLQ-------------------------SPPIITLEPVETVINAGGKIIL 1497
Query: 1421 EAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHL 1480
+A G P+P + W RQG + S + ++ L + + L + + ++DT E A N +
Sbjct: 1498 NCQATGEPQPTITWSRQGHSI--SWDDRVNVLSNNS--LYIADAQKEDTSEFECVARNLM 1553
Query: 1481 G 1481
G
Sbjct: 1554 G 1554
Score = 52.4 bits (120), Expect = 2e-05
Identities = 63/252 (25%), Positives = 102/252 (40%), Gaps = 40/252 (15%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISL 1301
EN+ + G TC A N AG + + S V P + ++ GE++ L
Sbjct: 1265 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-------LPTFTELPGDVSLNKGEQLRL 1317
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+CK G P PK+ W N +I D +G E+ I+ E +G Y CTA N
Sbjct: 1318 SCKATGIPLPKLTWTFNNNIIPAHFD-----SVNGHSELVIERVSKEDSGTYVCTAENSV 1372
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
G ++A +V V E V + S + G I L
Sbjct: 1373 G--------FVKAIGFV-YVKEPPVFKGDYPSH--------------WIEPLGGNAI-LN 1408
Query: 1422 AKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
+ G P P ++W R+G ++ ++I +L +G+ L + +D G+ A N G
Sbjct: 1409 CEVKGDPTPTIQWNRKGVDI--EISHRIRQLGNGS--LAIYGTVNEDAGDYTCVATNEAG 1464
Query: 1482 VTATIAALSVES 1493
V +L+++S
Sbjct: 1465 VVERSMSLTLQS 1476
Score = 50.0 bits (114), Expect = 8e-05
Identities = 58/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG- 1279
++S L RI+ L + S G TC A N G ++ + G
Sbjct: 231 ENSDSLEVRILSGGSKLQIARSQHSDS--GNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 288
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+ P + +V+ GE + L C G P P I W + K I + I +G
Sbjct: 289 EIP------SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG-ST 341
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
++I A G Y C A+N G+ + I N+ Y P++ DE
Sbjct: 342 LNIYGALTSDTGKYTCVATNPAGE--EDRIFNLNVY-VTPTIRGN---KDE--------- 386
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
+ L T+V T+ I +E +A G P PQ+ WL+ G L S+ ++
Sbjct: 387 ---AEKLMTLVDTS----INIECRATGTPPPQINWLKNGLPLPLSSHIRL 429
Score = 48.0 bits (109), Expect = 3e-04
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 43/299 (14%)
Query: 1229 RIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL 1288
R++ + + ++ +S + V TC A N AG + + V +D
Sbjct: 428 RLLAAGQVIRIVRAQVSD--VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGT----- 480
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E TV+ G S+ C G P P + W + + + +T+S G+ + + +A E
Sbjct: 481 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTH--GMV-LQLLKAETE 537
Query: 1349 MAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPT 1408
+G Y C ASN+ G+ S IL + ++ E + +S ++ P
Sbjct: 538 DSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEIS-------------VIVNNP- 583
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+ L A GIP P++ W++ G L Q+ Q++ L G +L + +D
Sbjct: 584 ---------LELTCIASGIPAPKMTWMKDGRPLPQTD--QVQTLGGG-EVLRISTAQVED 631
Query: 1469 TGEIVFEAYNHLGVTATIAALSVE---SIVGTQEYRKPEWVTHMEELQAALKA-TQSVP 1523
TG A + G + V +I GT E P +T + Q L+ + +VP
Sbjct: 632 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDE---PRDITVLRNRQVTLECKSDAVP 687
Score = 46.4 bits (105), Expect = 0.001
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 59/323 (18%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N TV+ + +L C+ G P P I+W N L+ ++ R S + I + +
Sbjct: 850 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 909
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
A Y+CT +N G L ++ PS+ +DE T + + K P V
Sbjct: 910 A-TYECTVTNGAGDDKRTVDLTVQV---PPSI------ADEPTDFL------VTKHAPAV 953
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T T A G+P P + W + G LL DG IL+ +
Sbjct: 954 ITCT----------ASGVPFPSIHWTKNGIRLLPR--------GDGYRILSSGAI----- 990
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
EI+ NH G +A + S +R H+ E Q P+ + I
Sbjct: 991 -EILATQLNHAGRYTCVARNAAGS-----AHR--HVTLHVHE----PPVIQPQPSELHVI 1038
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+ + ++ EA +G P+P I W K+ + T R I +A ++
Sbjct: 1039 LNNPI----LLPCEA--TGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVRED 1090
Query: 1590 EGTYTCKAVSDIGLAVTKAKLQV 1612
GTY C A + G A+ K KL V
Sbjct: 1091 AGTYMCVAQNPAGTALGKIKLNV 1113
Score = 46.4 bits (105), Expect = 0.001
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 40/243 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS STS V P + + + TV + + L C G P
Sbjct: 1182 GHYTCMAANVAGSSSTSTKLTVHV-------PPRIRSTEGHYTVNENSQAILPCVADGIP 1234
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I+W + L+ + + G E+ ++ E +G Y C A+N G+ +
Sbjct: 1235 TPAINWKKDNVLLANLLG-KYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVS 1291
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + +P+ +E LP V+ +G+ +RL KA GIP
Sbjct: 1292 LTVHV---LPTFTE----------------------LPGDVSLNKGEQLRLSCKATGIPL 1326
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P++ W + + +G S L + V ++D+G V A N +G I +
Sbjct: 1327 PKLTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFV 1381
Query: 1490 SVE 1492
V+
Sbjct: 1382 YVK 1384
Score = 44.0 bits (99), Expect = 0.005
Identities = 56/241 (23%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 1253 TCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPK 1312
TC A N AG + V I G ++ L +TV++ C G P P+
Sbjct: 729 TCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE-------CIAEGVPTPR 781
Query: 1313 IDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I W + + S ++G +HI+ A G Y C A+N G
Sbjct: 782 ITW-RKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAG---------- 828
Query: 1373 EAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQV 1432
+D + D++ P + PT +T L +A GIPKP +
Sbjct: 829 ---------------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSI 873
Query: 1433 RWLRQGTEL-LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
W + G L + + L G+ ++ P V DDT N G L+V
Sbjct: 874 NWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV--DDTATYECTVTNGAGDDKRTVDLTV 931
Query: 1492 E 1492
+
Sbjct: 932 Q 932
Score = 43.6 bits (98), Expect = 0.007
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 39/242 (16%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AGS + V E I P E +++ I L C+ G P
Sbjct: 1001 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQ------PSELHVILNNP-ILLPCEATGTP 1053
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + T+ GL I A E AG Y C A N G +
Sbjct: 1054 SPFITWQKEGINVNTSGRNHAVLPSGGL---QISRAVREDAGTYMCVAQNPAGTALGKIK 1110
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
LN++ VP V +P + + + V K I L +A G+P
Sbjct: 1111 LNVQ----VPPV----------------ISPHLKEYVIAV-----DKPITLSCEADGLPP 1145
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W + G +++S ++ L G+ +T V D G A N G ++T L
Sbjct: 1146 PDITWHKDGRAIVESIRQRV--LSSGSLQITF--VQPGDAGHYTCMAANVAGSSSTSTKL 1201
Query: 1490 SV 1491
+V
Sbjct: 1202 TV 1203
Score = 43.2 bits (97), Expect = 0.009
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 36/243 (14%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG VS V E I+G E +V+ + L C G P
Sbjct: 540 GKYTCIASNEAGEVSKHFILKVLEPPHINGSEEH-----EEISVIVNNPLELTCIASGIP 594
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEI-HIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
PK+ W + + + + Q G E+ I A E G Y C AS+ G E
Sbjct: 595 APKMTWMKDGRPLPQTDQV----QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY 650
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
++ + P+++ D P +T + + LE K+ +P
Sbjct: 651 LVRVHV---PPNIAGTDE--------------------PRDITVLRNRQVTLECKSDAVP 687
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P + WLR G E LQ+T ++ L G L + DT A N G T
Sbjct: 688 PPVITWLRNG-ERLQATP-RVRILSGG-RYLQINNADLGDTANYTCVASNIAGKTTREFI 744
Query: 1489 LSV 1491
L+V
Sbjct: 745 LTV 747
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 1225 ELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLV 1284
E++ RI Q + +++D G TC A N AG V S S ++ I
Sbjct: 1429 EISHRIRQLGNGSLAIYGTVNEDA-GDYTCVATNEAGVVERSMSLTLQSPPII------T 1481
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKE 1344
L P+E T + G +I LNC+ G P P I W I + + S ++I +
Sbjct: 1482 LEPVE-TVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS----LYIAD 1536
Query: 1345 AFPEMAGIYKCTASNQFG 1362
A E ++C A N G
Sbjct: 1537 AQKEDTSEFECVARNLMG 1554
Score = 40.3 bits (90), Expect = 0.066
Identities = 51/191 (26%), Positives = 72/191 (37%), Gaps = 33/191 (17%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEAFPEMA 1350
TV+ +++L CK P P I W N E+L T R R SG + I A
Sbjct: 670 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR----VRILSGGRYLQINNADLGDT 725
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
Y C ASN GK + E IL + P +K P +
Sbjct: 726 ANYTCVASNIAGKTTREFILTVN-------------------------VPPNIKGGPQSL 760
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
K LE A G+P P++ W + G +L + L++G L + + DTG
Sbjct: 761 VILLNKSTVLECIAEGVPTPRITWRKDGA-VLAGNHARYSILENG--FLHIQSAHVTDTG 817
Query: 1471 EIVFEAYNHLG 1481
+ A N G
Sbjct: 818 RYLCMATNAAG 828
Score = 40.3 bits (90), Expect = 0.066
Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 44/259 (16%)
Query: 1282 PLVLAP-LENTTVMDGERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCE 1339
P V++P L+ + + I+L+C+ G P P I W + + ++E+ R +S SG +
Sbjct: 1116 PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLS---SGSLQ 1172
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I + P AG Y C A+N G ST L + +VP
Sbjct: 1173 ITFVQ--PGDAGHYTCMAANVAGSSSTSTKLTV----HVP-------------------- 1206
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST-EYQIEELDDGTSI 1458
PRI ++ T E L A GIP P + W + L +Y E +
Sbjct: 1207 PRI-RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE---- 1261
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
L + V +D+G A N G +L+V + E + E+L+ + KA
Sbjct: 1262 LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKA 1321
Query: 1519 TQSVP------TFVKEIIP 1531
T +P TF IIP
Sbjct: 1322 T-GIPLPKLTWTFNNNIIP 1339
Score = 34.7 bits (76), Expect = 3.3
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 1547 SGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVT 1606
SG P P++ W K+ + I+ + +I RT I+ D G YTC A++ G +
Sbjct: 27 SGFPPPDLSWLKNEQPIKLNTNTLIV-PGGRTLQIIRAKVSD-GGEYTCIAINQAGESKK 84
Query: 1607 KAKLQVF 1613
K L V+
Sbjct: 85 KFSLTVY 91
Score = 34.3 bits (75), Expect = 4.3
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 4/98 (4%)
Query: 1516 LKATQSVPTFVKEIIPERVHE-EEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENK 1574
+K VP + + E V ++ +T G P P+I W+KD + I R + +
Sbjct: 1109 IKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 1168
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ G YTC A + G + T KL V
Sbjct: 1169 GSLQITFVQPGD---AGHYTCMAANVAGSSSTSTKLTV 1203
Score = 33.9 bits (74), Expect = 5.7
Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+E+I E + +T +A +G P P I W K++K I + + + I ++
Sbjct: 196 REVIVETISNPVTLTCDA--TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 253
Query: 1587 KDLEGTYTCKAVSDIGLA 1604
G YTC A + G A
Sbjct: 254 HSDSGNYTCIASNMEGKA 271
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B protein.
Length = 1960
Score = 63.3 bits (147), Expect = 8e-09
Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 27/245 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 12 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 71
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 72 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 110
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 111 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 166
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE E + E +A Q V +
Sbjct: 167 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSV 226
Query: 1526 VKEII 1530
+K ++
Sbjct: 227 LKRLL 231
Score = 58.8 bits (136), Expect = 2e-07
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 8/126 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 75 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 127
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 128 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 187
Query: 1369 ILNIEA 1374
L I++
Sbjct: 188 ELRIQS 193
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 97 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 156
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 157 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 191
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKK--ATKDLEGTYTCKAVS 1599
FEAI G+P P + WYKD+ V D + + +E T + + A+KD G YTC A +
Sbjct: 368 FEAIIEGDPQPSVTWYKDS-VQLVDSTRLSQQQEGTTYSLVLRHVASKD-AGVYTCLAQN 425
Query: 1600 DIGLAVTKAKLQV 1612
G + KA+L V
Sbjct: 426 TGGQVLCKAELLV 438
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE- 1572
+ LK+ PTF++E+ E V + VT S P + W KD + + R +I
Sbjct: 1446 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISA 1505
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+N TI + G YTC + +G T L+ +R
Sbjct: 1506 TLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 1548
Score = 44.8 bits (101), Expect = 0.003
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTD-ERFIIENKENRTTCT 1581
P F +E+ E V +G P P I WYKD K ++ D +IE+ +
Sbjct: 6 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 65
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ T G Y C A S G T K+ V
Sbjct: 66 LDSLTGVDSGQYMCFAASAAGNCSTLGKILV 96
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 63.3 bits (147), Expect = 8e-09
Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 27/245 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 636 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 695
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 696 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 734
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 735 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 790
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE E + E +A Q V +
Sbjct: 791 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSV 850
Query: 1526 VKEII 1530
+K ++
Sbjct: 851 LKRLL 855
Score = 58.8 bits (136), Expect = 2e-07
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 8/126 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 699 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 751
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 752 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 811
Query: 1369 ILNIEA 1374
L I++
Sbjct: 812 ELRIQS 817
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 721 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 608 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 667
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 668 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKK--ATKDLEGTYTCKAVS 1599
FEAI G+P P + WYKD+ V D + + +E T + + A+KD G YTC A +
Sbjct: 992 FEAIIEGDPQPSVTWYKDS-VQLVDSTRLSQQQEGTTYSLVLRHVASKD-AGVYTCLAQN 1049
Query: 1600 DIGLAVTKAKLQV 1612
G + KA+L V
Sbjct: 1050 TGGQVLCKAELLV 1062
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE- 1572
+ LK+ PTF++E+ E V + VT S P + W KD + + R +I
Sbjct: 2070 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISA 2129
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+N TI + G YTC + +G T L+ +R
Sbjct: 2130 TLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 63.3 bits (147), Expect = 8e-09
Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 27/245 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 636 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 695
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 696 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 734
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 735 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 790
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE E + E +A Q V +
Sbjct: 791 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSV 850
Query: 1526 VKEII 1530
+K ++
Sbjct: 851 LKRLL 855
Score = 58.8 bits (136), Expect = 2e-07
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 8/126 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 699 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 751
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 752 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 811
Query: 1369 ILNIEA 1374
L I++
Sbjct: 812 ELRIQS 817
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 721 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 608 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 667
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 668 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKK--ATKDLEGTYTCKAVS 1599
FEAI G+P P + WYKD+ V D + + +E T + + A+KD G YTC A +
Sbjct: 992 FEAIIEGDPQPSVTWYKDS-VQLVDSTRLSQQQEGTTYSLVLRHVASKD-AGVYTCLAQN 1049
Query: 1600 DIGLAVTKAKLQV 1612
G + KA+L V
Sbjct: 1050 TGGQVLCKAELLV 1062
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE- 1572
+ LK+ PTF++E+ E V + VT S P + W KD + + R +I
Sbjct: 2070 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISA 2129
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+N TI + G YTC + +G T L+ +R
Sbjct: 2130 TLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 63.3 bits (147), Expect = 8e-09
Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 27/245 (11%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
L + T GE + L C++ G P P I W+ + K ++ + G C + +
Sbjct: 636 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 695
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
+G Y C A++ G CST + ++ VP F + V+A P
Sbjct: 696 VDSGQYMCFAASAAGNCSTLGKILVQ----VP----------------PRFVNK-VRASP 734
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ-IEELDDGTSILTMPEVYQ 1466
V EG+ + G P PQ+RW + G L ++Q + E G +L + +
Sbjct: 735 FV----EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 790
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVES-IVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+D G E N LG A L ++S ++ QE E + E +A Q V +
Sbjct: 791 EDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSV 850
Query: 1526 VKEII 1530
+K ++
Sbjct: 851 LKRLL 855
Score = 58.8 bits (136), Expect = 2e-07
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 8/126 (6%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A + AG+ ST G +V+ P + + + ++GE C I G P
Sbjct: 699 GQYMCFAASAAGNCSTLGKILVQVP-------PRFVNKVRASPFVEGEDAQFTCTIEGAP 751
Query: 1310 WPKIDWFHNEKLIETARDI-TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
+P+I W+ + L+ T T+S +SGL + I+ A E G+Y+C N+ G
Sbjct: 752 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 811
Query: 1369 ILNIEA 1374
L I++
Sbjct: 812 ELRIQS 817
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERF--IIENKENR 1577
Q P FV ++ E E F G P P+I WYKD ++ T +F + E +
Sbjct: 721 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I+ A+K+ G Y C+ V+ +G A A+L++
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 815
Score = 46.4 bits (105), Expect = 0.001
Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 1502 KPEWVTHMEELQAALKA-TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN 1560
K WV + +Q L P F +E+ E V +G P P I WYKD
Sbjct: 608 KSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDG 667
Query: 1561 KVIRTD-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K ++ D +IE+ + + T G Y C A S G T K+ V
Sbjct: 668 KAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 720
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKK--ATKDLEGTYTCKAVS 1599
FEAI G+P P + WYKD+ V D + + +E T + + A+KD G YTC A +
Sbjct: 992 FEAIIEGDPQPSVTWYKDS-VQLVDSTRLSQQQEGTTYSLVLRHVASKD-AGVYTCLAQN 1049
Query: 1600 DIGLAVTKAKLQV 1612
G + KA+L V
Sbjct: 1050 TGGQVLCKAELLV 1062
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 1514 AALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE- 1572
+ LK+ PTF++E+ E V + VT S P + W KD + + R +I
Sbjct: 2070 SGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISA 2129
Query: 1573 NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+N TI + G YTC + +G T L+ +R
Sbjct: 2130 TLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 62.9 bits (146), Expect = 1e-08
Identities = 90/379 (23%), Positives = 147/379 (38%), Gaps = 69/379 (18%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 318 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 368
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 369 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 426
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 427 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 463
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P ++W + L Y + E +GT L +P +D TG
Sbjct: 464 NRPALLDCAFFGSPLPTIQWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 519
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L E + P W+ E A+ S+ +F ++
Sbjct: 520 CVARNKLGMAKNEVHL---------EIKDPTWIVKQPEY--AVVQRGSMVSFECKV---- 564
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
H+ + + +LW KDN+ + +DERF ++ + + + D GTY
Sbjct: 565 KHDHTL-----------SLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSGTY 609
Query: 1594 TCKAVSDIGLAVTKAKLQV 1612
TC A + + A L V
Sbjct: 610 TCVANTTLDSVSASAVLSV 628
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/316 (23%), Positives = 126/316 (39%), Gaps = 40/316 (12%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK-SGLCEIHI-KEAFPEM-AGIY 1353
E I + C+ G+P P W N + +D ++ + +G I+I E E G+Y
Sbjct: 57 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 116
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ ++ P K +T
Sbjct: 117 QCTARNERGA----------------AVSNNIVVRPSRS-------PLWTKEKLEPITLQ 153
Query: 1414 EGKLIRLEAKA-IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 154 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 210
Query: 1472 -IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME-ELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ ++ E + E A + + PTF+
Sbjct: 211 YICYARFNHTQTIQQKQPISVK-VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 269
Query: 1530 IPERVHEE---EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
EE +++ E I G PTP I W K++ ++ R + +N E T I +
Sbjct: 270 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVS 326
Query: 1587 KDLEGTYTCKAVSDIG 1602
+ G Y C A + +G
Sbjct: 327 EADSGNYQCIAKNALG 342
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 274 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 329
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 330 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 368
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 62.5 bits (145), Expect = 1e-08
Identities = 90/379 (23%), Positives = 146/379 (38%), Gaps = 69/379 (18%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 317 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 367
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 368 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 425
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 426 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 462
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P + W + L Y + E +GT L +P +D TG
Sbjct: 463 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 518
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L E + P W+ E A+ S+ +F ++
Sbjct: 519 CVARNKLGMAKNEVHL---------EIKDPTWIVKQPEY--AVVQRGSMVSFECKV---- 563
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
H+ + + +LW KDN+ + +DERF ++ + + + D GTY
Sbjct: 564 KHDHTL-----------SLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSGTY 608
Query: 1594 TCKAVSDIGLAVTKAKLQV 1612
TC A + + A L V
Sbjct: 609 TCVANTTLDSVSASAVLSV 627
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/316 (23%), Positives = 126/316 (39%), Gaps = 40/316 (12%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK-SGLCEIHI-KEAFPEM-AGIY 1353
E I + C+ G+P P W N + +D ++ + +G I+I E E G+Y
Sbjct: 56 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 115
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ ++ P K +T
Sbjct: 116 QCTARNERGA----------------AVSNNIVVRPSRS-------PLWTKEKLEPITLQ 152
Query: 1414 EGKLIRLEAKA-IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 153 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 209
Query: 1472 -IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME-ELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ ++ E + E A + + PTF+
Sbjct: 210 YICYARFNHTQTIQQKQPISVK-VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 268
Query: 1530 IPERVHEE---EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
EE +++ E I G PTP I W K++ ++ R + +N E T I +
Sbjct: 269 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVS 325
Query: 1587 KDLEGTYTCKAVSDIG 1602
+ G Y C A + +G
Sbjct: 326 EADSGNYQCIAKNALG 341
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 273 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 328
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 329 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 367
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus protein.
Length = 1236
Score = 62.5 bits (145), Expect = 1e-08
Identities = 90/379 (23%), Positives = 146/379 (38%), Gaps = 69/379 (18%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 323 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 373
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 374 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 431
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 432 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 468
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P + W + L Y + E +GT L +P +D TG
Sbjct: 469 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 524
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L E + P W+ E A+ S+ +F ++
Sbjct: 525 CVARNKLGMAKNEVHL---------EIKDPTWIVKQPEY--AVVQRGSMVSFECKV---- 569
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
H+ + + +LW KDN+ + +DERF ++ + + + D GTY
Sbjct: 570 KHDHTL-----------SLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSGTY 614
Query: 1594 TCKAVSDIGLAVTKAKLQV 1612
TC A + + A L V
Sbjct: 615 TCVANTTLDSVSASAVLSV 633
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/316 (23%), Positives = 126/316 (39%), Gaps = 40/316 (12%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK-SGLCEIHI-KEAFPEM-AGIY 1353
E I + C+ G+P P W N + +D ++ + +G I+I E E G+Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ ++ P K +T
Sbjct: 122 QCTARNERGA----------------AVSNNIVVRPSRS-------PLWTKEKLEPITLQ 158
Query: 1414 EGKLIRLEAKA-IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 159 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 215
Query: 1472 -IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME-ELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ ++ E + E A + + PTF+
Sbjct: 216 YICYARFNHTQTIQQKQPISVK-VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 274
Query: 1530 IPERVHEE---EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
EE +++ E I G PTP I W K++ ++ R + +N E T I +
Sbjct: 275 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVS 331
Query: 1587 KDLEGTYTCKAVSDIG 1602
+ G Y C A + +G
Sbjct: 332 EADSGNYQCIAKNALG 347
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 279 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 334
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 335 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 373
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 62.5 bits (145), Expect = 1e-08
Identities = 90/379 (23%), Positives = 146/379 (38%), Gaps = 69/379 (18%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 323 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 373
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 374 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 431
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 432 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 468
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P + W + L Y + E +GT L +P +D TG
Sbjct: 469 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 524
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L E + P W+ E A+ S+ +F ++
Sbjct: 525 CVARNKLGMAKNEVHL---------EIKDPTWIVKQPEY--AVVQRGSMVSFECKV---- 569
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
H+ + + +LW KDN+ + +DERF ++ + + + D GTY
Sbjct: 570 KHDHTL-----------SLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSGTY 614
Query: 1594 TCKAVSDIGLAVTKAKLQV 1612
TC A + + A L V
Sbjct: 615 TCVANTTLDSVSASAVLSV 633
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/316 (23%), Positives = 126/316 (39%), Gaps = 40/316 (12%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK-SGLCEIHI-KEAFPEM-AGIY 1353
E I + C+ G+P P W N + +D ++ + +G I+I E E G+Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ ++ P K +T
Sbjct: 122 QCTARNERGA----------------AVSNNIVVRPSRS-------PLWTKEKLEPITLQ 158
Query: 1414 EGKLIRLEAKA-IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 159 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 215
Query: 1472 -IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME-ELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ ++ E + E A + + PTF+
Sbjct: 216 YICYARFNHTQTIQQKQPISVK-VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 274
Query: 1530 IPERVHEE---EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
EE +++ E I G PTP I W K++ ++ R + +N E T I +
Sbjct: 275 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVS 331
Query: 1587 KDLEGTYTCKAVSDIG 1602
+ G Y C A + +G
Sbjct: 332 EADSGNYQCIAKNALG 347
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 279 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 334
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 335 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 373
>X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein.
Length = 1142
Score = 62.1 bits (144), Expect = 2e-08
Identities = 29/90 (32%), Positives = 49/90 (54%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F+ +I V G+P P+++W K+ IR D +F+I N + T I
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1108
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
++ + GTYTC+AV+++G A+ + KL+V
Sbjct: 1109 RRPSPFDAGTYTCRAVNELGEALAECKLEV 1138
Score = 60.1 bits (139), Expect = 8e-08
Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP L PL + V+ G +LNC + G P PK+ W N+ I I+ + G+ +
Sbjct: 1048 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQ-GVLTL 1106
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+I+ P AG Y C A N+ G+ EC L +
Sbjct: 1107 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1138
Score = 40.7 bits (91), Expect = 0.050
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 1547 SGNPTPEILWYKDNKVIRTDE-RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAV 1605
+G P P W K ++V T E R IE + + ++ I+ A ++ EG YT K + +G V
Sbjct: 570 TGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 629
Query: 1606 TKAKLQV 1612
LQV
Sbjct: 630 ASIFLQV 636
Score = 35.9 bits (79), Expect = 1.4
Identities = 55/238 (23%), Positives = 91/238 (38%), Gaps = 25/238 (10%)
Query: 1263 VSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLI 1322
V T+G E + ++ VL + + TV E+ C++ W+ N +
Sbjct: 421 VITNGGQC-EAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEV 478
Query: 1323 ETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ-FGKCSTEC-ILNIEAYEYVPS 1380
++ ITIS ++ I + PE G Y G S + L I+ EYVP
Sbjct: 479 RPSKRITISHV-GRFHKLVIDDVRPEDEGDYTFVPDGYALGSLSAKLNFLEIKV-EYVPK 536
Query: 1381 VSEEDVLSD--EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
+ D KTS+ + G +RL+ G P P WL+ G
Sbjct: 537 QEPPKIHLDCSGKTSE-------------NAIVVVAGNKLRLDVSITGEPPPVATWLK-G 582
Query: 1439 TELLQSTE--YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E+ +TE +IE+ D +S + + ++D G + N +G L V +
Sbjct: 583 DEVFTTTEGRTRIEKRVDCSSFV-IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV 639
>BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein C,
fast type protein.
Length = 1141
Score = 62.1 bits (144), Expect = 2e-08
Identities = 29/90 (32%), Positives = 49/90 (54%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F+ +I V G+P P+++W K+ IR D +F+I N + T I
Sbjct: 1048 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNI 1107
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
++ + GTYTC+AV+++G A+ + KL+V
Sbjct: 1108 RRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
Score = 60.1 bits (139), Expect = 8e-08
Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP L PL + V+ G +LNC + G P PK+ W N+ I I+ + G+ +
Sbjct: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQ-GVLTL 1105
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+I+ P AG Y C A N+ G+ EC L +
Sbjct: 1106 NIRRPSPFDAGTYTCRAVNELGEALAECKLEV 1137
Score = 40.7 bits (91), Expect = 0.050
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 1547 SGNPTPEILWYKDNKVIRTDE-RFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAV 1605
+G P P W K ++V T E R IE + + ++ I+ A ++ EG YT K + +G V
Sbjct: 569 TGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDV 628
Query: 1606 TKAKLQV 1612
LQV
Sbjct: 629 ASIFLQV 635
Score = 35.5 bits (78), Expect = 1.9
Identities = 54/237 (22%), Positives = 90/237 (37%), Gaps = 24/237 (10%)
Query: 1263 VSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLI 1322
V T+G E + ++ VL + + TV E+ C++ W+ N +
Sbjct: 421 VITNGGQC-EAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTG-KWYKNGVEV 478
Query: 1323 ETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC-ILNIEAYEYVPSV 1381
++ ITIS ++ I + PE G Y S + L I+ EYVP
Sbjct: 479 RPSKRITISHV-GRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV-EYVPKQ 536
Query: 1382 SEEDVLSD--EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGT 1439
+ D KTS+ + G +RL+ G P P WL+ G
Sbjct: 537 EPPKIHLDCSGKTSE-------------NAIVVVAGNKLRLDVSITGEPPPVATWLK-GD 582
Query: 1440 ELLQSTE--YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
E+ +TE +IE+ D +S + + ++D G + N +G L V +
Sbjct: 583 EVFTTTEGRTRIEKRVDCSSFV-IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDV 638
>AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein.
Length = 1289
Score = 61.7 bits (143), Expect = 2e-08
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDW-FHNEKLIET---ARDITISRQKSG 1336
AP L PL + T + G+ + L CK+ GRP P I W ++ +++T + T+S SG
Sbjct: 773 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 832
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPS 1380
+ I P+ +GIY C A+N G ST + ++ P+
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPN 876
Score = 43.6 bits (98), Expect = 0.007
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 5/104 (4%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ----STEYQIE 1450
++E AP + L V T G + L+ K G PKP + W +L S Y +
Sbjct: 769 IQEVAPEFLVPLVDV-TCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVS 827
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
D G L + + D+G A N G T+T A + V+ +
Sbjct: 828 SCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGV 871
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat protein
LRIG1 protein.
Length = 1093
Score = 61.3 bits (142), Expect = 3e-08
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 10/120 (8%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
++ D GV +C A+N AGS+S + + V E P ++ PLE+ V GE ++L
Sbjct: 661 DVKIDDAGVYSCTAQNSAGSISANATLTVLE-------TPSLVVPLEDRVVSVGETVALQ 713
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CK G P P+I WF ++ + ++ L ++ E AG Y C SN G
Sbjct: 714 CKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLV---VQNVVAEDAGRYTCEMSNTLG 770
Score = 44.0 bits (99), Expect = 0.005
Identities = 49/206 (23%), Positives = 86/206 (41%), Gaps = 35/206 (16%)
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQ 1466
T+ TTT + RLE A G P PQ+ W + G T+ + E ++ + D + + +V
Sbjct: 609 TIRTTT---VARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDD-DVFFITDVKI 664
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFV 1526
DD G A N G +I+A + +++ T P+ V
Sbjct: 665 DDAGVYSCTAQNSAG---SISANATLTVLET-------------------------PSLV 696
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+ V E V + +GNP P I W+K ++ + ER + +N+ ++
Sbjct: 697 VPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHL-TPDNQ-LLVVQNVV 754
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ G YTC+ + +G ++L V
Sbjct: 755 AEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 40.3 bits (90), Expect = 0.066
Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 30/200 (15%)
Query: 1301 LNCKILGRPWPKIDWFHNEKL-IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASN 1359
L C G P P+I W + AR+ + I + + AG+Y CTA N
Sbjct: 618 LECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQN 676
Query: 1360 QFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIR 1419
G S L + E S V R+V G+ +
Sbjct: 677 SAGSISANATLTVL----------------ETPSLVVPLEDRVVSV---------GETVA 711
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L+ KA G P P++ W + G L TE L +L + V +D G E N
Sbjct: 712 LQCKATGNPPPRITWFK-GDRPLSLTER--HHLTPDNQLLVVQNVVAEDAGRYTCEMSNT 768
Query: 1480 LGVTATIAALSVESIVGTQE 1499
LG + LSV G ++
Sbjct: 769 LGTERAHSQLSVLPAAGCRK 788
>AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 61.3 bits (142), Expect = 3e-08
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 10/120 (8%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
++ D GV +C A+N AGS+S + + V E P ++ PLE+ V GE ++L
Sbjct: 51 DVKIDDAGVYSCTAQNSAGSISANATLTVLE-------TPSLVVPLEDRVVSVGETVALQ 103
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CK G P P+I WF ++ + ++ L ++ E AG Y C SN G
Sbjct: 104 CKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLV---VQNVVAEDAGRYTCEMSNTLG 160
Score = 41.9 bits (94), Expect = 0.022
Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 32/195 (16%)
Query: 1419 RLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
RLE A G P PQ+ W + G T+ + E ++ + D + + +V DD G A
Sbjct: 7 RLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDD-DVFFITDVKIDDAGVYSCTAQ 65
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
N G +I+A + +++ T P+ V + V
Sbjct: 66 NSAG---SISANATLTVLET-------------------------PSLVVPLEDRVVSVG 97
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E V + +GNP P I W+K ++ + ER + +N+ ++ + G YTC+
Sbjct: 98 ETVALQCKATGNPPPRITWFKGDRPLSLTERHHL-TPDNQ-LLVVQNVVAEDAGRYTCEM 155
Query: 1598 VSDIGLAVTKAKLQV 1612
+ +G ++L V
Sbjct: 156 SNTLGTERAHSQLSV 170
Score = 40.3 bits (90), Expect = 0.066
Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 30/200 (15%)
Query: 1301 LNCKILGRPWPKIDWFHNEKL-IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASN 1359
L C G P P+I W + AR+ + I + + AG+Y CTA N
Sbjct: 8 LECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQN 66
Query: 1360 QFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIR 1419
G S L + E S V R+V G+ +
Sbjct: 67 SAGSISANATLTVL----------------ETPSLVVPLEDRVVSV---------GETVA 101
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L+ KA G P P++ W + G L TE L +L + V +D G E N
Sbjct: 102 LQCKATGNPPPRITWFK-GDRPLSLTER--HHLTPDNQLLVVQNVVAEDAGRYTCEMSNT 158
Query: 1480 LGVTATIAALSVESIVGTQE 1499
LG + LSV G ++
Sbjct: 159 LGTERAHSQLSVLPAAGCRK 178
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens cDNA
FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 61.3 bits (142), Expect = 3e-08
Identities = 93/400 (23%), Positives = 149/400 (37%), Gaps = 70/400 (17%)
Query: 1221 KDSTELTPR---IIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
K EL P II PL L ++E D G TC A N AG + G ++
Sbjct: 78 KGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAINEAGRAT--GKITLDV---- 130
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISR-QKSG 1336
G P+ + + ++ G ++L C + G P P I W + + +R ++S +
Sbjct: 131 -GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLR 189
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
+ I + G Y C A NQFGK + E T V
Sbjct: 190 TGALFILNLWASDKGTYICEAENQFGK-----------------------IQSETTVTVT 226
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAI-GIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
++ P+V EG+ + L + G P P+ RW++ LLQ+ + DG
Sbjct: 227 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR--SDG 284
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + V D GE A N G ++ V ++ T + H +++
Sbjct: 285 S--LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-VLPT--------IQHGQQI--- 330
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L + +P VT SGNP P ++W K ++I T +
Sbjct: 331 LSTIEGIP----------------VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD 374
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ + + G Y C A + G A K +L V+ R
Sbjct: 375 G--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVR 412
Score = 46.0 bits (104), Expect = 0.001
Identities = 55/242 (22%), Positives = 96/242 (39%), Gaps = 30/242 (12%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TC A N AG+ + + S +V I ++ + ++G ++L CK G P
Sbjct: 297 GEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL-------STIEGIPVTLPCKASGNP 349
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P + W +LI T+ S G +++ E +G Y CTA+N G +
Sbjct: 350 KPSVIWSKKGELISTS-SAKFSAGADG--SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 406
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L + Y ++ LS +K P ++ G+ + L + +P
Sbjct: 407 LTV--YVRPRVFGDQRGLSQDK---------------PVEISVLAGEEVTLPCEVKSLPP 449
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAAL 1489
P + W ++ T+L+ + L G+ +T E D+G + A N G L
Sbjct: 450 PIITWAKE-TQLISPFSPRHTFLPSGSMKIT--ETRTSDSGMYLCVATNIAGNVTQAVKL 506
Query: 1490 SV 1491
+V
Sbjct: 507 NV 508
Score = 43.6 bits (98), Expect = 0.007
Identities = 57/271 (21%), Positives = 99/271 (36%), Gaps = 36/271 (13%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N AG+ + T +AP ++ V G+ + CK G P
Sbjct: 18 GIYGCLASNSAGTDK-------QNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIP 70
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P++ WF + + + + I GL + I+E AG Y C A N+ G+ + +
Sbjct: 71 PPQVKWFKGDLELRPSTFLIID-PLLGL--LKIQETQDLDAGDYTCVAINEAGRATGKIT 127
Query: 1370 LNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPK 1429
L++ +P + P V+ G + L G P+
Sbjct: 128 LDVG-------------------------SPPVFIQEPADVSMEIGSNVTLPCYVQGYPE 162
Query: 1430 PQVRWLRQGTELLQSTEYQIEELDD-GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P ++W R + S + + + T L + ++ D G + EA N G +
Sbjct: 163 PTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETT 222
Query: 1489 LSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
++V +V P +E Q L T
Sbjct: 223 VTVTGLVAPLIGISPSVANVIEGQQLTLPCT 253
Score = 40.3 bits (90), Expect = 0.066
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 30/155 (19%)
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF- 1398
+ IK A P+ AGIY C ASN G +D++ S +
Sbjct: 7 LFIKNAAPKDAGIYGCLASNSAG-------------------------TDKQNSTLRYIE 41
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
AP+++ + + + G + +E K GIP PQV+W + EL ST I+ L +
Sbjct: 42 APKLM-VVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPL---LGL 97
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVES 1493
L + E D G+ A N G L V S
Sbjct: 98 LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 132
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLE-GTYTCK 1596
+I E SG P P++ W+K + +R II+ + T+DL+ G YTC
Sbjct: 58 DITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI---QETQDLDAGDYTCV 114
Query: 1597 AVSDIGLAVTKAKLQV 1612
A+++ G A K L V
Sbjct: 115 AINEAGRATGKITLDV 130
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein LRIG1
protein.
Length = 1093
Score = 61.3 bits (142), Expect = 3e-08
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 10/120 (8%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
++ D GV +C A+N AGS+S + + V E P ++ PLE+ V GE ++L
Sbjct: 661 DVKIDDAGVYSCTAQNSAGSISANATLTVLE-------TPSLVVPLEDRVVSVGETVALQ 713
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CK G P P+I WF ++ + ++ L ++ E AG Y C SN G
Sbjct: 714 CKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLV---VQNVVAEDAGRYTCEMSNTLG 770
Score = 44.0 bits (99), Expect = 0.005
Identities = 49/206 (23%), Positives = 86/206 (41%), Gaps = 35/206 (16%)
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQ 1466
T+ TTT + RLE A G P PQ+ W + G T+ + E ++ + D + + +V
Sbjct: 609 TIRTTT---VARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDD-DVFFITDVKI 664
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFV 1526
DD G A N G +I+A + +++ T P+ V
Sbjct: 665 DDAGVYSCTAQNSAG---SISANATLTVLET-------------------------PSLV 696
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+ V E V + +GNP P I W+K ++ + ER + +N+ ++
Sbjct: 697 VPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHL-TPDNQ-LLVVQNVV 754
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ G YTC+ + +G ++L V
Sbjct: 755 AEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 40.3 bits (90), Expect = 0.066
Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 30/200 (15%)
Query: 1301 LNCKILGRPWPKIDWFHNEKL-IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASN 1359
L C G P P+I W + AR+ + I + + AG+Y CTA N
Sbjct: 618 LECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQN 676
Query: 1360 QFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIR 1419
G S L + E S V R+V G+ +
Sbjct: 677 SAGSISANATLTVL----------------ETPSLVVPLEDRVVSV---------GETVA 711
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L+ KA G P P++ W + G L TE L +L + V +D G E N
Sbjct: 712 LQCKATGNPPPRITWFK-GDRPLSLTER--HHLTPDNQLLVVQNVVAEDAGRYTCEMSNT 768
Query: 1480 LGVTATIAALSVESIVGTQE 1499
LG + LSV G ++
Sbjct: 769 LGTERAHSQLSVLPAAGCRK 788
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein LIG-1
protein.
Length = 1094
Score = 61.3 bits (142), Expect = 3e-08
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 10/120 (8%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
++ D GV +C A+N AGS+S + + V E P ++ PLE+ V GE ++L
Sbjct: 661 DVKIDDAGVYSCTAQNSAGSISANATLTVLE-------TPSLVVPLEDRVVSVGETVALQ 713
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CK G P P+I WF ++ + ++ L ++ E AG Y C SN G
Sbjct: 714 CKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLV---VQNVVAEDAGRYTCEMSNTLG 770
Score = 44.4 bits (100), Expect = 0.004
Identities = 49/206 (23%), Positives = 86/206 (41%), Gaps = 35/206 (16%)
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQ 1466
T+ TTT + RLE A G P PQ+ W + G T+ + E ++ + D + + +V
Sbjct: 609 TIRTTT---MARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDD-DVFFITDVKI 664
Query: 1467 DDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFV 1526
DD G A N G +I+A + +++ T P+ V
Sbjct: 665 DDAGVYSCTAQNSAG---SISANATLTVLET-------------------------PSLV 696
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+ V E V + +GNP P I W+K ++ + ER + +N+ ++
Sbjct: 697 VPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHL-TPDNQ-LLVVQNVV 754
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ G YTC+ + +G ++L V
Sbjct: 755 AEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 40.3 bits (90), Expect = 0.066
Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 30/200 (15%)
Query: 1301 LNCKILGRPWPKIDWFHNEKL-IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASN 1359
L C G P P+I W + AR+ + I + + AG+Y CTA N
Sbjct: 618 LECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV-FFITDVKIDDAGVYSCTAQN 676
Query: 1360 QFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIR 1419
G S L + E S V R+V G+ +
Sbjct: 677 SAGSISANATLTVL----------------ETPSLVVPLEDRVVSV---------GETVA 711
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L+ KA G P P++ W + G L TE L +L + V +D G E N
Sbjct: 712 LQCKATGNPPPRITWFK-GDRPLSLTER--HHLTPDNQLLVVQNVVAEDAGRYTCEMSNT 768
Query: 1480 LGVTATIAALSVESIVGTQE 1499
LG + LSV G ++
Sbjct: 769 LGTERAHSQLSVLPAAGCRK 788
>AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 60.9 bits (141), Expect = 4e-08
Identities = 66/318 (20%), Positives = 127/318 (39%), Gaps = 33/318 (10%)
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
+ L+C+ +G P P I W N + ++ + I + S + I G Y C A+
Sbjct: 699 VLLHCEAIGHPRPTISWARNGEEVQFSDRILLQPDDS----LQILAPVEADVGFYTCNAT 754
Query: 1359 NQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLI 1418
N G S + + V + S V++ EK P + + + + T +G +
Sbjct: 755 NALGYDSVSIAVTLAGKPLVKT-SRMTVINTEK--------PAVTVDIGSTIKTVQGVNV 805
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
+ + G+P+ +V W R ++L L +G+ +LT V D G A N
Sbjct: 806 TINCQVAGVPEAEVTWFRNKSKLGSP-----HHLHEGSLLLT--NVSSSDQGLYSCRAAN 858
Query: 1479 -HLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT-QSVPTFVKEIIPER--V 1534
H +T + L ++ P+ T +E+++A L AT ++P+ + + + +
Sbjct: 859 LHGELTESTQLLILD---------PPQVPTQLEDIRALLAATGPNLPSVLTSPLGTQLVL 909
Query: 1535 HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
G+P P I W+ + I T + + +G ++
Sbjct: 910 DPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQGEFS 969
Query: 1595 CKAVSDIGLAVTKAKLQV 1612
C A ++ G+ + KA L +
Sbjct: 970 CLAQNEAGVLMQKASLVI 987
Score = 58.0 bits (134), Expect = 3e-07
Identities = 61/272 (22%), Positives = 111/272 (40%), Gaps = 21/272 (7%)
Query: 1230 IIQPLKALNVLEENISKDLIGVVTCRAENFAG------SVSTSGSSIVE--EQTCIDGDA 1281
++QP +L +L + D +G TC A N G +V+ +G +V+ T I+ +
Sbjct: 729 LLQPDDSLQILAP-VEAD-VGFYTCNATNALGYDSVSIAVTLAGKPLVKTSRMTVINTEK 786
Query: 1282 PLVLAPLENTT-VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P V + +T + G +++NC++ G P ++ WF N+ + + + + L
Sbjct: 787 PAVTVDIGSTIKTVQGVNVTINCQVAGVPEAEVTWFRNKSKLGSPHHL----HEGSLLLT 842
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
++ + G+Y C A+N G+ + L I VP+ E+ + +
Sbjct: 843 NVSSS---DQGLYSCRAANLHGELTESTQLLILDPPQVPTQLED--IRALLAATGPNLPS 897
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+ L T + G L G P P + W G ++ +T L G IL
Sbjct: 898 VLTSPLGTQLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAG-QILQ 956
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
+ + GE A N GV A+L ++
Sbjct: 957 VANLSGGSQGEFSCLAQNEAGVLMQKASLVIQ 988
Score = 46.0 bits (104), Expect = 0.001
Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 17/154 (11%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIV----EEQTCIDG----------DAPL 1283
++L N+S G+ +CRA N G ++ S ++ + T ++ + P
Sbjct: 838 SLLLTNVSSSDQGLYSCRAANLHGELTESTQLLILDPPQVPTQLEDIRALLAATGPNLPS 897
Query: 1284 VL-APLENTTVMD-GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
VL +PL V+D G L C I G P P I WFH + I TA +T +G +
Sbjct: 898 VLTSPLGTQLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQI-LQ 956
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAY 1375
+ G + C A N+ G + L I+ Y
Sbjct: 957 VANLSGGSQGEFSCLAQNEAGVLMQKASLVIQDY 990
Score = 39.5 bits (88), Expect = 0.12
Identities = 45/202 (22%), Positives = 85/202 (42%), Gaps = 23/202 (11%)
Query: 1399 APRIVKALPTVVTTTEGKL-IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
A +V L V G L + L +AIG P+P + W R G E +Q ++ + + DD
Sbjct: 679 ASEVVTHLGQTVALASGTLSVLLHCEAIGHPRPTISWARNGEE-VQFSDRILLQPDDSLQ 737
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
IL E D G A N LG ++S+ + + K +T + + A+
Sbjct: 738 ILAPVEA---DVGFYTCNATNALGYD----SVSIAVTLAGKPLVKTSRMTVINTEKPAV- 789
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
T + + +K + + V+ VT +G P E+ W+++ + + +
Sbjct: 790 -TVDIGSTIKTV--QGVN----VTINCQVAGVPEAEVTWFRNKSKLGSPHHL------HE 836
Query: 1578 TTCTIKKATKDLEGTYTCKAVS 1599
+ + + +G Y+C+A +
Sbjct: 837 GSLLLTNVSSSDQGLYSCRAAN 858
>AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 60.9 bits (141), Expect = 4e-08
Identities = 66/318 (20%), Positives = 127/318 (39%), Gaps = 33/318 (10%)
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
+ L+C+ +G P P I W N + ++ + I + S + I G Y C A+
Sbjct: 699 VLLHCEAIGHPRPTISWARNGEEVQFSDRILLQPDDS----LQILAPVEADVGFYTCNAT 754
Query: 1359 NQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLI 1418
N G S + + V + S V++ EK P + + + + T +G +
Sbjct: 755 NALGYDSVSIAVTLAGKPLVKT-SRMTVINTEK--------PAVTVDIGSTIKTVQGVNV 805
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
+ + G+P+ +V W R ++L L +G+ +LT V D G A N
Sbjct: 806 TINCQVAGVPEAEVTWFRNKSKLGSP-----HHLHEGSLLLT--NVSSSDQGLYSCRAAN 858
Query: 1479 -HLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT-QSVPTFVKEIIPER--V 1534
H +T + L ++ P+ T +E+++A L AT ++P+ + + + +
Sbjct: 859 LHGELTESTQLLILD---------PPQVPTQLEDIRALLAATGPNLPSVLTSPLGTQLVL 909
Query: 1535 HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
G+P P I W+ + I T + + +G ++
Sbjct: 910 DPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQGEFS 969
Query: 1595 CKAVSDIGLAVTKAKLQV 1612
C A ++ G+ + KA L +
Sbjct: 970 CLAQNEAGVLMQKASLVI 987
Score = 58.0 bits (134), Expect = 3e-07
Identities = 61/272 (22%), Positives = 111/272 (40%), Gaps = 21/272 (7%)
Query: 1230 IIQPLKALNVLEENISKDLIGVVTCRAENFAG------SVSTSGSSIVE--EQTCIDGDA 1281
++QP +L +L + D +G TC A N G +V+ +G +V+ T I+ +
Sbjct: 729 LLQPDDSLQILAP-VEAD-VGFYTCNATNALGYDSVSIAVTLAGKPLVKTSRMTVINTEK 786
Query: 1282 PLVLAPLENTT-VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P V + +T + G +++NC++ G P ++ WF N+ + + + + L
Sbjct: 787 PAVTVDIGSTIKTVQGVNVTINCQVAGVPEAEVTWFRNKSKLGSPHHL----HEGSLLLT 842
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
++ + G+Y C A+N G+ + L I VP+ E+ + +
Sbjct: 843 NVSSS---DQGLYSCRAANLHGELTESTQLLILDPPQVPTQLED--IRALLAATGPNLPS 897
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+ L T + G L G P P + W G ++ +T L G IL
Sbjct: 898 VLTSPLGTQLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAG-QILQ 956
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
+ + GE A N GV A+L ++
Sbjct: 957 VANLSGGSQGEFSCLAQNEAGVLMQKASLVIQ 988
Score = 46.0 bits (104), Expect = 0.001
Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 17/154 (11%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIV----EEQTCIDG----------DAPL 1283
++L N+S G+ +CRA N G ++ S ++ + T ++ + P
Sbjct: 838 SLLLTNVSSSDQGLYSCRAANLHGELTESTQLLILDPPQVPTQLEDIRALLAATGPNLPS 897
Query: 1284 VL-APLENTTVMD-GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
VL +PL V+D G L C I G P P I WFH + I TA +T +G +
Sbjct: 898 VLTSPLGTQLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQI-LQ 956
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAY 1375
+ G + C A N+ G + L I+ Y
Sbjct: 957 VANLSGGSQGEFSCLAQNEAGVLMQKASLVIQDY 990
Score = 39.5 bits (88), Expect = 0.12
Identities = 45/202 (22%), Positives = 85/202 (42%), Gaps = 23/202 (11%)
Query: 1399 APRIVKALPTVVTTTEGKL-IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
A +V L V G L + L +AIG P+P + W R G E +Q ++ + + DD
Sbjct: 679 ASEVVTHLGQTVALASGTLSVLLHCEAIGHPRPTISWARNGEE-VQFSDRILLQPDDSLQ 737
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
IL E D G A N LG ++S+ + + K +T + + A+
Sbjct: 738 ILAPVEA---DVGFYTCNATNALGYD----SVSIAVTLAGKPLVKTSRMTVINTEKPAV- 789
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
T + + +K + + V+ VT +G P E+ W+++ + + +
Sbjct: 790 -TVDIGSTIKTV--QGVN----VTINCQVAGVPEAEVTWFRNKSKLGSPHHL------HE 836
Query: 1578 TTCTIKKATKDLEGTYTCKAVS 1599
+ + + +G Y+C+A +
Sbjct: 837 GSLLLTNVSSSDQGLYSCRAAN 858
>AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 60.9 bits (141), Expect = 4e-08
Identities = 66/318 (20%), Positives = 127/318 (39%), Gaps = 33/318 (10%)
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
+ L+C+ +G P P I W N + ++ + I + S + I G Y C A+
Sbjct: 699 VLLHCEAIGHPRPTISWARNGEEVQFSDRILLQPDDS----LQILAPVEADVGFYTCNAT 754
Query: 1359 NQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLI 1418
N G S + + V + S V++ EK P + + + + T +G +
Sbjct: 755 NALGYDSVSIAVTLAGKPLVKT-SRMTVINTEK--------PAVTVDIGSTIKTVQGVNV 805
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
+ + G+P+ +V W R ++L L +G+ +LT V D G A N
Sbjct: 806 TINCQVAGVPEAEVTWFRNKSKLGSP-----HHLHEGSLLLT--NVSSSDQGLYSCRAAN 858
Query: 1479 -HLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT-QSVPTFVKEIIPER--V 1534
H +T + L ++ P+ T +E+++A L AT ++P+ + + + +
Sbjct: 859 LHGELTESTQLLILD---------PPQVPTQLEDIRALLAATGPNLPSVLTSPLGTQLVL 909
Query: 1535 HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYT 1594
G+P P I W+ + I T + + +G ++
Sbjct: 910 DPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLSGGSQGEFS 969
Query: 1595 CKAVSDIGLAVTKAKLQV 1612
C A ++ G+ + KA L +
Sbjct: 970 CLAQNEAGVLMQKASLVI 987
Score = 58.0 bits (134), Expect = 3e-07
Identities = 61/272 (22%), Positives = 111/272 (40%), Gaps = 21/272 (7%)
Query: 1230 IIQPLKALNVLEENISKDLIGVVTCRAENFAG------SVSTSGSSIVE--EQTCIDGDA 1281
++QP +L +L + D +G TC A N G +V+ +G +V+ T I+ +
Sbjct: 729 LLQPDDSLQILAP-VEAD-VGFYTCNATNALGYDSVSIAVTLAGKPLVKTSRMTVINTEK 786
Query: 1282 PLVLAPLENTT-VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P V + +T + G +++NC++ G P ++ WF N+ + + + + L
Sbjct: 787 PAVTVDIGSTIKTVQGVNVTINCQVAGVPEAEVTWFRNKSKLGSPHHL----HEGSLLLT 842
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAP 1400
++ + G+Y C A+N G+ + L I VP+ E+ + +
Sbjct: 843 NVSSS---DQGLYSCRAANLHGELTESTQLLILDPPQVPTQLED--IRALLAATGPNLPS 897
Query: 1401 RIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILT 1460
+ L T + G L G P P + W G ++ +T L G IL
Sbjct: 898 VLTSPLGTQLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAG-QILQ 956
Query: 1461 MPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
+ + GE A N GV A+L ++
Sbjct: 957 VANLSGGSQGEFSCLAQNEAGVLMQKASLVIQ 988
Score = 46.0 bits (104), Expect = 0.001
Identities = 42/154 (27%), Positives = 66/154 (42%), Gaps = 17/154 (11%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIV----EEQTCIDG----------DAPL 1283
++L N+S G+ +CRA N G ++ S ++ + T ++ + P
Sbjct: 838 SLLLTNVSSSDQGLYSCRAANLHGELTESTQLLILDPPQVPTQLEDIRALLAATGPNLPS 897
Query: 1284 VL-APLENTTVMD-GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
VL +PL V+D G L C I G P P I WFH + I TA +T +G +
Sbjct: 898 VLTSPLGTQLVLDPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQI-LQ 956
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAY 1375
+ G + C A N+ G + L I+ Y
Sbjct: 957 VANLSGGSQGEFSCLAQNEAGVLMQKASLVIQDY 990
Score = 39.5 bits (88), Expect = 0.12
Identities = 45/202 (22%), Positives = 85/202 (42%), Gaps = 23/202 (11%)
Query: 1399 APRIVKALPTVVTTTEGKL-IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
A +V L V G L + L +AIG P+P + W R G E +Q ++ + + DD
Sbjct: 679 ASEVVTHLGQTVALASGTLSVLLHCEAIGHPRPTISWARNGEE-VQFSDRILLQPDDSLQ 737
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
IL E D G A N LG ++S+ + + K +T + + A+
Sbjct: 738 ILAPVEA---DVGFYTCNATNALGYD----SVSIAVTLAGKPLVKTSRMTVINTEKPAV- 789
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
T + + +K + + V+ VT +G P E+ W+++ + + +
Sbjct: 790 -TVDIGSTIKTV--QGVN----VTINCQVAGVPEAEVTWFRNKSKLGSPHHL------HE 836
Query: 1578 TTCTIKKATKDLEGTYTCKAVS 1599
+ + + +G Y+C+A +
Sbjct: 837 GSLLLTNVSSSDQGLYSCRAAN 858
>AJ489257-1|CAD33526.2| 461|Homo sapiens triadin protein.
Length = 461
Score = 60.5 bits (140), Expect = 6e-08
Identities = 74/279 (26%), Positives = 116/279 (41%), Gaps = 22/279 (7%)
Query: 234 KTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEK 293
+ EI KDK E++ + E K Q+ + K++ K+K+ + K EK KEK
Sbjct: 139 RKKEIHKDKTEKQEK-PERKIQTKVTHKEKEKGKEKVREKE--------KPEKKATHKEK 189
Query: 294 IEDVALKPVRKDSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSE-E 352
IE KP K ++K ++ +E E+ E K QE Q K K ++ S+ +
Sbjct: 190 IEKKE-KPETKTVAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPK 248
Query: 353 SKESTGKRR--QREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKET--EDR 408
KE K + E+ Q + ++ P L TE+ S+ T
Sbjct: 249 EKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPA 308
Query: 409 INTKD--TRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCA 466
+ K+ +K T E K + K EKE D+ K K S + T ++ A
Sbjct: 309 LEEKEGEKKKAEKKVTSETKKKAEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAA 368
Query: 467 LKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEE 505
+A D +KE+ K K P E + P GK+Q K+E
Sbjct: 369 QAAAKKDEKKEDSKKTK-----KPAEVEQPKGKKQEKKE 402
Score = 42.7 bits (96), Expect = 0.012
Identities = 65/304 (21%), Positives = 118/304 (38%), Gaps = 19/304 (6%)
Query: 198 KLETKSWRKPR---LEESLEEVGPTKGVNEPEVCHWR-KPKTSEILKDKNEEEIRVQEMK 253
K++TK K + E+ E+ P K E + KP+T + K+ +++ + E
Sbjct: 157 KIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTVAKE--QKKAKTAEKS 214
Query: 254 KQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVAL-KPVRKDSL-MDEK 311
++ TK EVK ++K+ T +K K P EKE E A+ K +KD
Sbjct: 215 EEKTKK-EVKGGKQEKVKQTAAKVK-EVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRY 272
Query: 312 SSEI---SELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESK------ESTGKRRQ 362
+I +L+ + E +PT + LE E+ K T K+ +
Sbjct: 273 MIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKAE 332
Query: 363 REEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWT 422
+E+I +K + + + +K+ E + ++K T+KP+
Sbjct: 333 KEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQ 392
Query: 423 QEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPD 482
+ K + P + K E + ++ + EE+ A+ S K+E K
Sbjct: 393 PKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSSKKAVPGKKEEKTT 452
Query: 483 KVSE 486
K E
Sbjct: 453 KTVE 456
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 60.1 bits (139), Expect = 8e-08
Identities = 90/381 (23%), Positives = 144/381 (37%), Gaps = 73/381 (19%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 304 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 354
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 355 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 412
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 413 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 449
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P + W + L Y + E +GT L +P +D TG
Sbjct: 450 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 505
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L ++ T ++PE+
Sbjct: 506 CVARNKLGMAKNEVHLEIKD--ATWIVKQPEYAV-------------------------- 537
Query: 1534 VHEEEIVTFEAIYSGNPTPE--ILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +V+FE + T +LW KDN+ + +DERF ++ + + + D G
Sbjct: 538 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSG 593
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
TYTC A + + A L V
Sbjct: 594 TYTCVANTTLDSVSASAVLSV 614
Score = 42.7 bits (96), Expect = 0.012
Identities = 74/313 (23%), Positives = 125/313 (39%), Gaps = 53/313 (16%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHI-KEAFPE-MAGIY 1353
E I + C+ G+P P W N + +D + + +G I+I E E G+Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ + +P K +T
Sbjct: 122 QCTARNERG----------------AAVSNNIVVRPSR-------SPLWTKEKLEPITLQ 158
Query: 1414 EGKLIRLEAK-AIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 159 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 215
Query: 1472 -IVFEAYNHLGVTATIAALSVESI-VGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ I + R P ++T E A+ K +E+
Sbjct: 216 YICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLT--PEGNASNK---------EEL 264
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+++ E I G PTP I W K++ ++ R + +N E T I ++
Sbjct: 265 ------RGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVSEAD 315
Query: 1590 EGTYTCKAVSDIG 1602
G Y C A + +G
Sbjct: 316 SGNYQCIAKNALG 328
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 315
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 316 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 354
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 60.1 bits (139), Expect = 8e-08
Identities = 90/381 (23%), Positives = 144/381 (37%), Gaps = 73/381 (19%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 304 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 354
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 355 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 412
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 413 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 449
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P + W + L Y + E +GT L +P +D TG
Sbjct: 450 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 505
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L ++ T ++PE+
Sbjct: 506 CVARNKLGMAKNEVHLEIKD--ATWIVKQPEYAV-------------------------- 537
Query: 1534 VHEEEIVTFEAIYSGNPTPE--ILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +V+FE + T +LW KDN+ + +DERF ++ + + + D G
Sbjct: 538 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSG 593
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
TYTC A + + A L V
Sbjct: 594 TYTCVANTTLDSVSASAVLSV 614
Score = 42.7 bits (96), Expect = 0.012
Identities = 74/313 (23%), Positives = 125/313 (39%), Gaps = 53/313 (16%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHI-KEAFPE-MAGIY 1353
E I + C+ G+P P W N + +D + + +G I+I E E G+Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ + +P K +T
Sbjct: 122 QCTARNERG----------------AAVSNNIVVRPSR-------SPLWTKEKLEPITLQ 158
Query: 1414 EGKLIRLEAK-AIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 159 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 215
Query: 1472 -IVFEAYNHLGVTATIAALSVESI-VGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ I + R P ++T E A+ K +E+
Sbjct: 216 YICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLT--PEGNASNK---------EEL 264
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+++ E I G PTP I W K++ ++ R + +N E T I ++
Sbjct: 265 ------RGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVSEAD 315
Query: 1590 EGTYTCKAVSDIG 1602
G Y C A + +G
Sbjct: 316 SGNYQCIAKNALG 328
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 315
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 316 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 354
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 60.1 bits (139), Expect = 8e-08
Identities = 90/381 (23%), Positives = 144/381 (37%), Gaps = 73/381 (19%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 317 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 367
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 368 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 425
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 426 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 462
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P + W + L Y + E +GT L +P +D TG
Sbjct: 463 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 518
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L ++ T ++PE+
Sbjct: 519 CVARNKLGMAKNEVHLEIKD--ATWIVKQPEYAV-------------------------- 550
Query: 1534 VHEEEIVTFEAIYSGNPTPE--ILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +V+FE + T +LW KDN+ + +DERF ++ + + + D G
Sbjct: 551 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSG 606
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
TYTC A + + A L V
Sbjct: 607 TYTCVANTTLDSVSASAVLSV 627
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/316 (23%), Positives = 126/316 (39%), Gaps = 40/316 (12%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK-SGLCEIHI-KEAFPEM-AGIY 1353
E I + C+ G+P P W N + +D ++ + +G I+I E E G+Y
Sbjct: 56 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 115
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ ++ P K +T
Sbjct: 116 QCTARNERGA----------------AVSNNIVVRPSRS-------PLWTKEKLEPITLQ 152
Query: 1414 EGKLIRLEAKA-IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 153 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 209
Query: 1472 -IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME-ELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ ++ E + E A + + PTF+
Sbjct: 210 YICYARFNHTQTIQQKQPISVK-VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 268
Query: 1530 IPERVHEE---EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
EE +++ E I G PTP I W K++ ++ R + +N E T I +
Sbjct: 269 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVS 325
Query: 1587 KDLEGTYTCKAVSDIG 1602
+ G Y C A + +G
Sbjct: 326 EADSGNYQCIAKNALG 341
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 273 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 328
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 329 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 367
>AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens cDNA
FLJ39139 fis, clone NTONG2009229. ).
Length = 410
Score = 60.1 bits (139), Expect = 8e-08
Identities = 33/103 (32%), Positives = 48/103 (46%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP + + V +G R+ L C++ G P P++ WF K + DI I + L +
Sbjct: 147 APRFIQKPRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 206
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSE 1383
I EAF + G Y C A+N G +T + IE S SE
Sbjct: 207 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 249
Score = 54.4 bits (125), Expect = 4e-06
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
APR ++ P EG + LE + G P P+VRW +G EL + + QI
Sbjct: 147 APRFIQK-PRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 205
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGT 1497
L + E ++DDTG A N G T A + +E T
Sbjct: 206 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASST 244
Score = 43.6 bits (98), Expect = 0.007
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTT 1579
+ P F+++ + V E V E +GNPTP + W+ + K + T + I + T
Sbjct: 146 AAPRFIQKPRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 205
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKL 1610
I +A +D G YTC A + G T A++
Sbjct: 206 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEV 236
Score = 37.5 bits (83), Expect = 0.47
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
F P K L EG+++ LE + G P Q +W RQG+E+ S +++I
Sbjct: 316 FPPVFTKELQNTAVA-EGQVVVLECRVRGAPPLQDQWFRQGSEIQDSPDFRI 366
Score = 36.7 bits (81), Expect = 0.81
Identities = 16/53 (30%), Positives = 28/53 (52%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK 1334
P+ L+NT V +G+ + L C++ G P + WF I+ + D I ++K
Sbjct: 318 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQDQWFRQGSEIQDSPDFRILQKK 370
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 60.1 bits (139), Expect = 8e-08
Identities = 90/381 (23%), Positives = 144/381 (37%), Gaps = 73/381 (19%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 311 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 361
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 362 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 419
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 420 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 456
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ L+ G P P + W + L Y + E +GT L +P +D TG
Sbjct: 457 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGT--LEIPVAQKDSTGTYT 512
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPER 1533
A N LG+ L ++ T ++PE+
Sbjct: 513 CVARNKLGMAKNEVHLEIKD--ATWIVKQPEYAV-------------------------- 544
Query: 1534 VHEEEIVTFEAIYSGNPTPE--ILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +V+FE + T +LW KDN+ + +DERF ++ + + + D G
Sbjct: 545 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSG 600
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
TYTC A + + A L V
Sbjct: 601 TYTCVANTTLDSVSASAVLSV 621
Score = 42.7 bits (96), Expect = 0.012
Identities = 74/313 (23%), Positives = 125/313 (39%), Gaps = 53/313 (16%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHI-KEAFPE-MAGIY 1353
E I + C+ G+P P W N + +D + + +G I+I E E G+Y
Sbjct: 69 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 128
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ + +P K +T
Sbjct: 129 QCTARNERG----------------AAVSNNIVVRPSR-------SPLWTKEKLEPITLQ 165
Query: 1414 EGKLIRLEAK-AIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 166 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 222
Query: 1472 -IVFEAYNHLGVTATIAALSVESI-VGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ I + R P ++T E A+ K +E+
Sbjct: 223 YICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLT--PEGNASNK---------EEL 271
Query: 1530 IPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDL 1589
+++ E I G PTP I W K++ ++ R + +N E T I ++
Sbjct: 272 ------RGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVSEAD 322
Query: 1590 EGTYTCKAVSDIG 1602
G Y C A + +G
Sbjct: 323 SGNYQCIAKNALG 335
Score = 37.5 bits (83), Expect = 0.47
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 267 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 322
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+G Y+C A N G + ++A Y + + VLS
Sbjct: 323 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLS 361
>Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C gene
protein.
Length = 1274
Score = 59.7 bits (138), Expect = 1e-07
Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP PL N +V+ G L C + G P PKI WF N L E AR S+Q G+
Sbjct: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ--GVL 1236
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ I++ P GIY C A+N G+ EC L +
Sbjct: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 41.9 bits (94), Expect = 0.022
Identities = 24/90 (26%), Positives = 42/90 (46%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F + ++ V G+P P+I W+K+ + D RF + +K+ T I
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K G Y C+A + G A + +L+V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
>X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding protein
C protein.
Length = 1274
Score = 59.7 bits (138), Expect = 1e-07
Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP PL N +V+ G L C + G P PKI WF N L E AR S+Q G+
Sbjct: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ--GVL 1236
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ I++ P GIY C A+N G+ EC L +
Sbjct: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 41.9 bits (94), Expect = 0.022
Identities = 24/90 (26%), Positives = 42/90 (46%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F + ++ V G+P P+I W+K+ + D RF + +K+ T I
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K G Y C+A + G A + +L+V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
>X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA for
receptor-related tyrosine kinase. ).
Length = 1338
Score = 59.7 bits (138), Expect = 1e-07
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 10/139 (7%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQ--TCIDGDAPLVLAPLENTTVM 1294
LN+ N+S G CRA N +G I++++ T D +AP +L L + TV
Sbjct: 619 LNLTIMNVSLQDSGTYACRARNVY-----TGEEILQKKEITIRDQEAPYLLRNLSDHTVA 673
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
+L+C G P P+I WF N I+ I + G + I+ E G+Y
Sbjct: 674 ISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILG---PGSSTLFIERVTEEDEGVYH 730
Query: 1355 CTASNQFGKCSTECILNIE 1373
C A+NQ G + L ++
Sbjct: 731 CKATNQKGSVESSAYLTVQ 749
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
Q P ++ + V T + +G P P+I W+K+N I+ + I+ +T
Sbjct: 658 QEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIIL--GPGSST 715
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++ T++ EG Y CKA + G + A L V
Sbjct: 716 LFIERVTEEDEGVYHCKATNQKGSVESSAYLTV 748
Score = 39.5 bits (88), Expect = 0.12
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%)
Query: 1384 EDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E++L ++ + ++ AP +++ L T L+ A G+P+PQ+ W + ++ Q
Sbjct: 645 EEILQKKEITIRDQEAPYLLRNLSDH-TVAISSSTTLDCHANGVPEPQITWFKNNHKIQQ 703
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
L G+S L + V ++D G +A N G + A L+V+ GT +
Sbjct: 704 EPGI---ILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQ---GTSDKSNL 757
Query: 1504 EWVT 1507
E +T
Sbjct: 758 ELIT 761
>U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding
protein-C protein.
Length = 1274
Score = 59.7 bits (138), Expect = 1e-07
Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP PL N +V+ G L C + G P PKI WF N L E AR S+Q G+
Sbjct: 1179 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ--GVL 1236
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ I++ P GIY C A+N G+ EC L +
Sbjct: 1237 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
Score = 41.9 bits (94), Expect = 0.022
Identities = 24/90 (26%), Positives = 42/90 (46%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F + ++ V G+P P+I W+K+ + D RF + +K+ T I
Sbjct: 1181 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1240
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K G Y C+A + G A + +L+V
Sbjct: 1241 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1270
>AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein C,
cardiac protein.
Length = 1273
Score = 59.7 bits (138), Expect = 1e-07
Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP PL N +V+ G L C + G P PKI WF N L E AR S+Q G+
Sbjct: 1178 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQ--GVL 1235
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
+ I++ P GIY C A+N G+ EC L +
Sbjct: 1236 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEV 1269
Score = 41.9 bits (94), Expect = 0.022
Identities = 24/90 (26%), Positives = 42/90 (46%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+F + ++ V G+P P+I W+K+ + D RF + +K+ T I
Sbjct: 1180 PSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEI 1239
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K G Y C+A + G A + +L+V
Sbjct: 1240 RKPCPFDGGIYVCRATNLQGEARCECRLEV 1269
>AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine kinase
1 (vascular endothelial growth factor/vascular perm
protein.
Length = 1338
Score = 59.7 bits (138), Expect = 1e-07
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 10/139 (7%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQ--TCIDGDAPLVLAPLENTTVM 1294
LN+ N+S G CRA N +G I++++ T D +AP +L L + TV
Sbjct: 619 LNLTIMNVSLQDSGTYACRARNVY-----TGEEILQKKEITIRDQEAPYLLRNLSDHTVA 673
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
+L+C G P P+I WF N I+ I + G + I+ E G+Y
Sbjct: 674 ISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILG---PGSSTLFIERVTEEDEGVYH 730
Query: 1355 CTASNQFGKCSTECILNIE 1373
C A+NQ G + L ++
Sbjct: 731 CKATNQKGSVESSAYLTVQ 749
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
Q P ++ + V T + +G P P+I W+K+N I+ + I+ +T
Sbjct: 658 QEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIIL--GPGSST 715
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++ T++ EG Y CKA + G + A L V
Sbjct: 716 LFIERVTEEDEGVYHCKATNQKGSVESSAYLTV 748
Score = 39.5 bits (88), Expect = 0.12
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%)
Query: 1384 EDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E++L ++ + ++ AP +++ L T L+ A G+P+PQ+ W + ++ Q
Sbjct: 645 EEILQKKEITIRDQEAPYLLRNLSDH-TVAISSSTTLDCHANGVPEPQITWFKNNHKIQQ 703
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
L G+S L + V ++D G +A N G + A L+V+ GT +
Sbjct: 704 EPGI---ILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQ---GTSDKSNL 757
Query: 1504 EWVT 1507
E +T
Sbjct: 758 ELIT 761
>AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine kinase
1 (vascular endothelial growth factor/vascular perm
protein.
Length = 1338
Score = 59.7 bits (138), Expect = 1e-07
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 10/139 (7%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQ--TCIDGDAPLVLAPLENTTVM 1294
LN+ N+S G CRA N +G I++++ T D +AP +L L + TV
Sbjct: 619 LNLTIMNVSLQDSGTYACRARNVY-----TGEEILQKKEITIRDQEAPYLLRNLSDHTVA 673
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
+L+C G P P+I WF N I+ I + G + I+ E G+Y
Sbjct: 674 ISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILG---PGSSTLFIERVTEEDEGVYH 730
Query: 1355 CTASNQFGKCSTECILNIE 1373
C A+NQ G + L ++
Sbjct: 731 CKATNQKGSVESSAYLTVQ 749
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
Q P ++ + V T + +G P P+I W+K+N I+ + I+ +T
Sbjct: 658 QEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIIL--GPGSST 715
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++ T++ EG Y CKA + G + A L V
Sbjct: 716 LFIERVTEEDEGVYHCKATNQKGSVESSAYLTV 748
Score = 39.5 bits (88), Expect = 0.12
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%)
Query: 1384 EDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E++L ++ + ++ AP +++ L T L+ A G+P+PQ+ W + ++ Q
Sbjct: 645 EEILQKKEITIRDQEAPYLLRNLSDH-TVAISSSTTLDCHANGVPEPQITWFKNNHKIQQ 703
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
L G+S L + V ++D G +A N G + A L+V+ GT +
Sbjct: 704 EPGI---ILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQ---GTSDKSNL 757
Query: 1504 EWVT 1507
E +T
Sbjct: 758 ELIT 761
>AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial growth
factor receptor protein.
Length = 1338
Score = 59.7 bits (138), Expect = 1e-07
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 10/139 (7%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQ--TCIDGDAPLVLAPLENTTVM 1294
LN+ N+S G CRA N +G I++++ T D +AP +L L + TV
Sbjct: 619 LNLTIMNVSLQDSGTYACRARNVY-----TGEEILQKKEITIRDQEAPYLLRNLSDHTVA 673
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
+L+C G P P+I WF N I+ I + G + I+ E G+Y
Sbjct: 674 ISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILG---PGSSTLFIERVTEEDEGVYH 730
Query: 1355 CTASNQFGKCSTECILNIE 1373
C A+NQ G + L ++
Sbjct: 731 CKATNQKGSVESSAYLTVQ 749
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
Q P ++ + V T + +G P P+I W+K+N I+ + I+ +T
Sbjct: 658 QEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIIL--GPGSST 715
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I++ T++ EG Y CKA + G + A L V
Sbjct: 716 LFIERVTEEDEGVYHCKATNQKGSVESSAYLTV 748
Score = 39.5 bits (88), Expect = 0.12
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%)
Query: 1384 EDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQ 1443
E++L ++ + ++ AP +++ L T L+ A G+P+PQ+ W + ++ Q
Sbjct: 645 EEILQKKEITIRDQEAPYLLRNLSDH-TVAISSSTTLDCHANGVPEPQITWFKNNHKIQQ 703
Query: 1444 STEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
L G+S L + V ++D G +A N G + A L+V+ GT +
Sbjct: 704 EPGI---ILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQ---GTSDKSNL 757
Query: 1504 EWVT 1507
E +T
Sbjct: 758 ELIT 761
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 59.7 bits (138), Expect = 1e-07
Identities = 54/216 (25%), Positives = 91/216 (42%), Gaps = 36/216 (16%)
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
E+ P+I P + +G ++LE A+G P PQ+ W R+ L S++ ++ + +
Sbjct: 116 EYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINW-RRSDGLPFSSKIKLRKF---S 171
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAAL 1516
+L +P Q+D G A N G L+ Y KP WV +++++ A+
Sbjct: 172 GVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTY--------YAKPHWVQLIKDVEIAV 223
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKEN 1576
E+ + +E SG P P W K+ + +ER IEN
Sbjct: 224 --------------------EDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIEN--- 260
Query: 1577 RTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
TI + G + C A + GL + A+L+V
Sbjct: 261 -GALTISNLSVTDSGMFQCIAENKHGLVYSSAELKV 295
Score = 38.3 bits (85), Expect = 0.27
Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 1289 ENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPE 1348
E G + L C LG P P+I+W ++ L +++ I + R+ SG+ E I E
Sbjct: 127 ETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSK-IKL-RKFSGVLE--IPNFQQE 182
Query: 1349 MAGIYKCTASNQFGK 1363
AG Y+C A N GK
Sbjct: 183 DAGSYECIAENSRGK 197
Score = 36.7 bits (81), Expect = 0.81
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 11/151 (7%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N++K G TC AEN G + + +V E T I LAP N V GE + L
Sbjct: 360 NVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRI------TLAP-SNMDVSVGESVILP 412
Query: 1303 CKILGRPWPKI--DWFHNEKLIETARDITISRQKSGLC--EIHIKEAFPEMAGIYKCTAS 1358
C++ P I W+ N L + +D + + G ++ I+ + +G Y C
Sbjct: 413 CQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQ 472
Query: 1359 NQFGKCSTECILNIEAYEYVPSVSEEDVLSD 1389
S+ L + P + D ++D
Sbjct: 473 TGVDSVSSAADLIVRGSPGPPENVKVDEITD 503
Score = 35.5 bits (78), Expect = 1.9
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 8/123 (6%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+S G+ C AEN G V +S V P+ + V G +SL+
Sbjct: 267 NLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMK----KLVQVQVGSLVSLD 322
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
CK P W + ++ I++ GL ++ +A AG Y C A NQFG
Sbjct: 323 CKPRASPRALSSWKKGDVSVQEHERISLLND-GGLKIANVTKAD---AGTYTCMAENQFG 378
Query: 1363 KCS 1365
K +
Sbjct: 379 KAN 381
>X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein.
Length = 1354
Score = 58.8 bits (136), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT + + E + SGNP P+I+W+KDN+ + D ++ K+ TI
Sbjct: 665 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL--KDGNRNLTI 722
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKA 1608
++ K+ EG YTC+A S +G A +A
Sbjct: 723 RRVRKEDEGLYTCQACSVLGCAKVEA 748
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDI 1328
+V + T ++ AP + LEN T GE I ++C G P P+I WF NE L+E + +
Sbjct: 653 VVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIV 712
Query: 1329 TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
K G + I+ E G+Y C A + G E IE
Sbjct: 713 L----KDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE 753
Score = 50.0 bits (114), Expect = 8e-05
Identities = 51/211 (24%), Positives = 91/211 (43%), Gaps = 23/211 (10%)
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+ ++V T G+ +R+ AK +G P P+++W + G L + + I+ +LT+ EV
Sbjct: 334 MESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPL--ESNHTIK----AGHVLTIMEVS 387
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+ DTG N + +S+ V Q K ++ ++ Q TQ++
Sbjct: 388 ERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEK-SLISPVDSYQYG--TTQTLTCT 444
Query: 1526 VKEI-IPERVH-----EEEIVT--FEAIYSGNPTPEILWYK------DNKVIRTDERFII 1571
V I P +H EEE +A+ NP P W NK+ +F +
Sbjct: 445 VYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFAL 504
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+N+T T+ ++ Y C+AV+ +G
Sbjct: 505 IEGKNKTVSTLVIQAANVSALYKCEAVNKVG 535
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
+E AP I L TT+ G+ I + A G P PQ+ W + L++ + L D
Sbjct: 660 LERVAPTITGNLENQ-TTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGI---VLKD 715
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
G LT+ V ++D G +A + LG A +E G QE
Sbjct: 716 GNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE---GAQE 757
Score = 34.3 bits (75), Expect = 4.3
Identities = 42/181 (23%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 1211 PIEKDSH--IIEKD-STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSG 1267
P K H ++ +D T+ + + L L + + +++ G+ TC A + + S
Sbjct: 261 PSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTI--DGVTRSDQGLYTCAASSGLMTKKNST 318
Query: 1268 SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD 1327
V E+ + + + L TV GER+ + K LG P P+I W+ N +E+
Sbjct: 319 FVRVHEKPFVAFGSGM--ESLVEATV--GERVRIPAKYLGYPPPEIKWYKNGIPLESNHT 374
Query: 1328 ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVL 1387
I K+G + I E G Y +N K ++++ Y P + E+ ++
Sbjct: 375 I-----KAGHV-LTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVY-VPPQIGEKSLI 427
Query: 1388 S 1388
S
Sbjct: 428 S 428
>L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase
protein.
Length = 1354
Score = 58.8 bits (136), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT + + E + SGNP P+I+W+KDN+ + D ++ K+ TI
Sbjct: 665 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL--KDGNRNLTI 722
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKA 1608
++ K+ EG YTC+A S +G A +A
Sbjct: 723 RRVRKEDEGLYTCQACSVLGCAKVEA 748
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDI 1328
+V + T ++ AP + LEN T GE I ++C G P P+I WF NE L+E + +
Sbjct: 653 VVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIV 712
Query: 1329 TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
K G + I+ E G+Y C A + G E IE
Sbjct: 713 L----KDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE 753
Score = 50.0 bits (114), Expect = 8e-05
Identities = 51/211 (24%), Positives = 91/211 (43%), Gaps = 23/211 (10%)
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+ ++V T G+ +R+ AK +G P P+++W + G L + + I+ +LT+ EV
Sbjct: 334 MESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPL--ESNHTIK----AGHVLTIMEVS 387
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+ DTG N + +S+ V Q K ++ ++ Q TQ++
Sbjct: 388 ERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEK-SLISPVDSYQYG--TTQTLTCT 444
Query: 1526 VKEI-IPERVH-----EEEIVT--FEAIYSGNPTPEILWYK------DNKVIRTDERFII 1571
V I P +H EEE +A+ NP P W NK+ +F +
Sbjct: 445 VYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFAL 504
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+N+T T+ ++ Y C+AV+ +G
Sbjct: 505 IEGKNKTVSTLVIQAANVSALYKCEAVNKVG 535
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
+E AP I L TT+ G+ I + A G P PQ+ W + L++ + L D
Sbjct: 660 LERVAPTITGNLENQ-TTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGI---VLKD 715
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
G LT+ V ++D G +A + LG A +E G QE
Sbjct: 716 GNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE---GAQE 757
Score = 34.3 bits (75), Expect = 4.3
Identities = 42/181 (23%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 1211 PIEKDSH--IIEKD-STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSG 1267
P K H ++ +D T+ + + L L + + +++ G+ TC A + + S
Sbjct: 261 PSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTI--DGVTRSDQGLYTCAASSGLMTKKNST 318
Query: 1268 SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD 1327
V E+ + + + L TV GER+ + K LG P P+I W+ N +E+
Sbjct: 319 FVRVHEKPFVAFGSGM--ESLVEATV--GERVRIPAKYLGYPPPEIKWYKNGIPLESNHT 374
Query: 1328 ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVL 1387
I K+G + I E G Y +N K ++++ Y P + E+ ++
Sbjct: 375 I-----KAGHV-LTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVY-VPPQIGEKSLI 427
Query: 1388 S 1388
S
Sbjct: 428 S 428
>BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) protein.
Length = 1356
Score = 58.8 bits (136), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT + + E + SGNP P+I+W+KDN+ + D ++ K+ TI
Sbjct: 667 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL--KDGNRNLTI 724
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKA 1608
++ K+ EG YTC+A S +G A +A
Sbjct: 725 RRVRKEDEGLYTCQACSVLGCAKVEA 750
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDI 1328
+V + T ++ AP + LEN T GE I ++C G P P+I WF NE L+E + +
Sbjct: 655 VVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIV 714
Query: 1329 TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
K G + I+ E G+Y C A + G E IE
Sbjct: 715 L----KDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE 755
Score = 49.2 bits (112), Expect = 1e-04
Identities = 51/211 (24%), Positives = 90/211 (42%), Gaps = 23/211 (10%)
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+ ++V T G+ +R+ AK +G P P+++W + G L + + I+ +LT+ EV
Sbjct: 336 MESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPL--ESNHTIK----AGHVLTIMEVS 389
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+ DTG N + +S+ V Q K ++ ++ Q TQ++
Sbjct: 390 ERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEK-SLISPVDSYQYG--TTQTLTCT 446
Query: 1526 VKEI-IPERVH-----EEEIVT--FEAIYSGNPTPEILWYK------DNKVIRTDERFII 1571
V I P +H EEE A+ NP P W NK+ +F +
Sbjct: 447 VYAIPPPHHIHWYWQLEEECANEPSHAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFAL 506
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+N+T T+ ++ Y C+AV+ +G
Sbjct: 507 IEGKNKTVSTLVIQAANVSALYKCEAVNKVG 537
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
+E AP I L TT+ G+ I + A G P PQ+ W + L++ + L D
Sbjct: 662 LERVAPTITGNLENQ-TTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGI---VLKD 717
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
G LT+ V ++D G +A + LG A +E G QE
Sbjct: 718 GNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE---GAQE 759
Score = 34.7 bits (76), Expect = 3.3
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 1211 PIEKDSH--IIEKD-STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSG 1267
P K H ++ +D T+ + + L L + + I++ G+ TC A + + S
Sbjct: 263 PSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTI--DGITRSDQGLYTCAASSGLMTKKNST 320
Query: 1268 SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD 1327
V E+ + + + L TV GER+ + K LG P P+I W+ N +E+
Sbjct: 321 FVRVHEKPFVAFGSGM--ESLVEATV--GERVRIPAKYLGYPPPEIKWYKNGIPLESNHT 376
Query: 1328 ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVL 1387
I K+G + I E G Y +N K ++++ Y P + E+ ++
Sbjct: 377 I-----KAGHV-LTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVY-VPPQIGEKSLI 429
Query: 1388 S 1388
S
Sbjct: 430 S 430
>AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial growth
factor receptor 2 protein.
Length = 1356
Score = 58.8 bits (136), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT + + E + SGNP P+I+W+KDN+ + D ++ K+ TI
Sbjct: 667 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL--KDGNRNLTI 724
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKA 1608
++ K+ EG YTC+A S +G A +A
Sbjct: 725 RRVRKEDEGLYTCQACSVLGCAKVEA 750
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDI 1328
+V + T ++ AP + LEN T GE I ++C G P P+I WF NE L+E + +
Sbjct: 655 VVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIV 714
Query: 1329 TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
K G + I+ E G+Y C A + G E IE
Sbjct: 715 L----KDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE 755
Score = 50.0 bits (114), Expect = 8e-05
Identities = 51/211 (24%), Positives = 91/211 (43%), Gaps = 23/211 (10%)
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+ ++V T G+ +R+ AK +G P P+++W + G L + + I+ +LT+ EV
Sbjct: 336 MESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPL--ESNHTIK----AGHVLTIMEVS 389
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+ DTG N + +S+ V Q K ++ ++ Q TQ++
Sbjct: 390 ERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEK-SLISPVDSYQYG--TTQTLTCT 446
Query: 1526 VKEI-IPERVH-----EEEIVT--FEAIYSGNPTPEILWYK------DNKVIRTDERFII 1571
V I P +H EEE +A+ NP P W NK+ +F +
Sbjct: 447 VYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFAL 506
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+N+T T+ ++ Y C+AV+ +G
Sbjct: 507 IEGKNKTVSTLVIQAANVSALYKCEAVNKVG 537
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
+E AP I L TT+ G+ I + A G P PQ+ W + L++ + L D
Sbjct: 662 LERVAPTITGNLENQ-TTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGI---VLKD 717
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
G LT+ V ++D G +A + LG A +E G QE
Sbjct: 718 GNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE---GAQE 759
Score = 34.3 bits (75), Expect = 4.3
Identities = 42/181 (23%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 1211 PIEKDSH--IIEKD-STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSG 1267
P K H ++ +D T+ + + L L + + +++ G+ TC A + + S
Sbjct: 263 PSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTI--DGVTRSDQGLYTCAASSGLMTKKNST 320
Query: 1268 SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD 1327
V E+ + + + L TV GER+ + K LG P P+I W+ N +E+
Sbjct: 321 FVRVHEKPFVAFGSGM--ESLVEATV--GERVRIPAKYLGYPPPEIKWYKNGIPLESNHT 376
Query: 1328 ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVL 1387
I K+G + I E G Y +N K ++++ Y P + E+ ++
Sbjct: 377 I-----KAGHV-LTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVY-VPPQIGEKSLI 429
Query: 1388 S 1388
S
Sbjct: 430 S 430
>AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein.
Length = 1356
Score = 58.8 bits (136), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT + + E + SGNP P+I+W+KDN+ + D ++ K+ TI
Sbjct: 667 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL--KDGNRNLTI 724
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKA 1608
++ K+ EG YTC+A S +G A +A
Sbjct: 725 RRVRKEDEGLYTCQACSVLGCAKVEA 750
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDI 1328
+V + T ++ AP + LEN T GE I ++C G P P+I WF NE L+E + +
Sbjct: 655 VVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIV 714
Query: 1329 TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
K G + I+ E G+Y C A + G E IE
Sbjct: 715 L----KDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE 755
Score = 50.0 bits (114), Expect = 8e-05
Identities = 51/211 (24%), Positives = 91/211 (43%), Gaps = 23/211 (10%)
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+ ++V T G+ +R+ AK +G P P+++W + G L + + I+ +LT+ EV
Sbjct: 336 MESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPL--ESNHTIK----AGHVLTIMEVS 389
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+ DTG N + +S+ V Q K ++ ++ Q TQ++
Sbjct: 390 ERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEK-SLISPVDSYQYG--TTQTLTCT 446
Query: 1526 VKEI-IPERVH-----EEEIVT--FEAIYSGNPTPEILWYK------DNKVIRTDERFII 1571
V I P +H EEE +A+ NP P W NK+ +F +
Sbjct: 447 VYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFAL 506
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+N+T T+ ++ Y C+AV+ +G
Sbjct: 507 IEGKNKTVSTLVIQAANVSALYKCEAVNKVG 537
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
+E AP I L TT+ G+ I + A G P PQ+ W + L++ + L D
Sbjct: 662 LERVAPTITGNLENQ-TTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGI---VLKD 717
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
G LT+ V ++D G +A + LG A +E G QE
Sbjct: 718 GNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE---GAQE 759
Score = 34.3 bits (75), Expect = 4.3
Identities = 42/181 (23%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 1211 PIEKDSH--IIEKD-STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSG 1267
P K H ++ +D T+ + + L L + + +++ G+ TC A + + S
Sbjct: 263 PSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTI--DGVTRSDQGLYTCAASSGLMTKKNST 320
Query: 1268 SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD 1327
V E+ + + + L TV GER+ + K LG P P+I W+ N +E+
Sbjct: 321 FVRVHEKPFVAFGSGM--ESLVEATV--GERVRIPAKYLGYPPPEIKWYKNGIPLESNHT 376
Query: 1328 ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVL 1387
I K+G + I E G Y +N K ++++ Y P + E+ ++
Sbjct: 377 I-----KAGHV-LTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVY-VPPQIGEKSLI 429
Query: 1388 S 1388
S
Sbjct: 430 S 430
>AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) variant
protein.
Length = 1451
Score = 58.8 bits (136), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PT + + E + SGNP P+I+W+KDN+ + D ++ K+ TI
Sbjct: 762 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVL--KDGNRNLTI 819
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKA 1608
++ K+ EG YTC+A S +G A +A
Sbjct: 820 RRVRKEDEGLYTCQACSVLGCAKVEA 845
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/105 (32%), Positives = 49/105 (46%), Gaps = 5/105 (4%)
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWF-HNEKLIETARDI 1328
+V + T ++ AP + LEN T GE I ++C G P P+I WF NE L+E + +
Sbjct: 750 VVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIV 809
Query: 1329 TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
K G + I+ E G+Y C A + G E IE
Sbjct: 810 L----KDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE 850
Score = 50.0 bits (114), Expect = 8e-05
Identities = 51/211 (24%), Positives = 91/211 (43%), Gaps = 23/211 (10%)
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+ ++V T G+ +R+ AK +G P P+++W + G L + + I+ +LT+ EV
Sbjct: 431 MESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPL--ESNHTIK----AGHVLTIMEVS 484
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTF 1525
+ DTG N + +S+ V Q K ++ ++ Q TQ++
Sbjct: 485 ERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEK-SLISPVDSYQYG--TTQTLTCT 541
Query: 1526 VKEI-IPERVH-----EEEIVT--FEAIYSGNPTPEILWYK------DNKVIRTDERFII 1571
V I P +H EEE +A+ NP P W NK+ +F +
Sbjct: 542 VYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFAL 601
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIG 1602
+N+T T+ ++ Y C+AV+ +G
Sbjct: 602 IEGKNKTVSTLVIQAANVSALYKCEAVNKVG 632
Score = 40.7 bits (91), Expect = 0.050
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
+E AP I L TT+ G+ I + A G P PQ+ W + L++ + L D
Sbjct: 757 LERVAPTITGNLENQ-TTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGI---VLKD 812
Query: 1455 GTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
G LT+ V ++D G +A + LG A +E G QE
Sbjct: 813 GNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIE---GAQE 854
Score = 34.7 bits (76), Expect = 3.3
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 1211 PIEKDSH--IIEKD-STELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSG 1267
P K H ++ +D T+ + + L L + + I++ G+ TC A + + S
Sbjct: 358 PSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTI--DGITRSDQGLYTCAASSGLMTKKNST 415
Query: 1268 SSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD 1327
V E+ + + + L TV GER+ + K LG P P+I W+ N +E+
Sbjct: 416 FVRVHEKPFVAFGSGM--ESLVEATV--GERVRIPAKYLGYPPPEIKWYKNGIPLESNHT 471
Query: 1328 ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVL 1387
I K+G + I E G Y +N K ++++ Y P + E+ ++
Sbjct: 472 I-----KAGHV-LTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVY-VPPQIGEKSLI 524
Query: 1388 S 1388
S
Sbjct: 525 S 525
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 58.0 bits (134), Expect = 3e-07
Identities = 81/321 (25%), Positives = 119/321 (37%), Gaps = 63/321 (19%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T G + + C LG P P I W I + +R + + I + AG
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSK-----ARLRKSQAVLEIPNVQLDDAG 365
Query: 1352 IYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVT 1411
IY+C A N GK S L + Y + EK +D +
Sbjct: 366 IYECRAENSRGKNSFRGQLQVYTYPHWV----------EKLNDTQ--------------- 400
Query: 1412 TTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE 1471
G +R E KA G P+P RWL+ G L S + ++E ++ +L + V Q D G
Sbjct: 401 LDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVEMVN---GVLMIHNVNQSDAGM 455
Query: 1472 IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP 1531
A N G A L + A T ++ K II
Sbjct: 456 YQCLAENKYGAIYASAELKI----------------------LASAPTFALNQLKKTII- 492
Query: 1532 ERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +++ V E G+P P I W K ++ +R ++R I + I A+K EG
Sbjct: 493 --VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD---GSLRILNASKSDEG 547
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
Y C+ + G A A L V
Sbjct: 548 KYVCRGENVFGSAEIIASLSV 568
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/259 (26%), Positives = 110/259 (42%), Gaps = 39/259 (15%)
Query: 1235 KALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
K+ VLE N+ D G+ CRAEN G S G V P + L +T +
Sbjct: 349 KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQL 401
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
G + CK G+P P W N + + +G+ IH AG+Y
Sbjct: 402 DSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV---EMVNGVLMIH--NVNQSDAGMY 456
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+C A N++G + + +E +L+ T FA +K T++ T
Sbjct: 457 QCLAENKYGA--------------IYASAELKILASAPT-----FALNQLK--KTIIVTK 495
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ +++ +E K G PKP + W ++G ++ + +I L DG+ L + + D G+ V
Sbjct: 496 DQEVV-IECKPQGSPKPTISW-KKGDRAVRENK-RIAILPDGS--LRILNASKSDEGKYV 550
Query: 1474 FEAYNHLGVTATIAALSVE 1492
N G IA+LSV+
Sbjct: 551 CRGENVFGSAEIIASLSVK 569
Score = 43.6 bits (98), Expect = 0.007
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 13/117 (11%)
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
E+ P+I P VT +G +++E A+G P P + W++ + L
Sbjct: 297 EYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-----RLRKSQ 351
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
++L +P V DD G A N G + L V Y P WV + + Q
Sbjct: 352 AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV--------YTYPHWVEKLNDTQ 400
Score = 43.2 bits (97), Expect = 0.009
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
Query: 1391 KTSDVEEFAPRIVKALPTVV--TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
K + ++ P V+ ++ T ++ K + L + G P P RWLR GTE+ ++Y+
Sbjct: 90 KQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYR 149
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
L DGT I++ P + D+G A N +G
Sbjct: 150 Y-SLIDGTFIISNPSEAK-DSGHYQCLATNTVG 180
Score = 39.9 bits (89), Expect = 0.087
Identities = 37/157 (23%), Positives = 64/157 (40%), Gaps = 12/157 (7%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGD 1280
K+ L+P+ + ++ N+++ G+ C AEN G++ S E +
Sbjct: 425 KNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASA-----ELKILASA 479
Query: 1281 APLVLAPLENTTVMDGER-ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
L L+ T ++ ++ + + CK G P P I W ++ + + I I S
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGS---- 535
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+ I A G Y C N FG S E I ++ E
Sbjct: 536 LRILNASKSDEGKYVCRGENVFG--SAEIIASLSVKE 570
Score = 36.7 bits (81), Expect = 0.81
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T D ++++LNC++ G P P W N I+ D S + EA + +G
Sbjct: 112 TDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEA--KDSG 169
Query: 1352 IYKCTASNQFG 1362
Y+C A+N G
Sbjct: 170 HYQCLATNTVG 180
Score = 35.9 bits (79), Expect = 1.4
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V E GNP P I W K N I + R ++++ I D G Y C+A +
Sbjct: 318 VKMECFALGNPVPTITWMKVNGYIPSKARL----RKSQAVLEIPNVQLDDAGIYECRAEN 373
Query: 1600 DIGLAVTKAKLQVF 1613
G + +LQV+
Sbjct: 374 SRGKNSFRGQLQVY 387
Score = 34.7 bits (76), Expect = 3.3
Identities = 29/76 (38%), Positives = 36/76 (47%), Gaps = 9/76 (11%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLEN 1290
I P +L +L N SK G CR EN GS S V+E T I+ L P +
Sbjct: 530 ILPDGSLRIL--NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE------LTP-KR 580
Query: 1291 TTVMDGERISLNCKIL 1306
T + GE I LNCK +
Sbjct: 581 TELTVGESIVLNCKAI 596
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 58.0 bits (134), Expect = 3e-07
Identities = 81/321 (25%), Positives = 119/321 (37%), Gaps = 63/321 (19%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T G + + C LG P P I W I + +R + + I + AG
Sbjct: 17 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSK-----ARLRKSQAVLEIPNVQLDDAG 71
Query: 1352 IYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVT 1411
IY+C A N GK S L + Y + EK +D +
Sbjct: 72 IYECRAENSRGKNSFRGQLQVYTYPHWV----------EKLNDTQ--------------- 106
Query: 1412 TTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE 1471
G +R E KA G P+P RWL+ G L S + ++E ++ +L + V Q D G
Sbjct: 107 LDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVEMVN---GVLMIHNVNQSDAGM 161
Query: 1472 IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP 1531
A N G A L + A T ++ K II
Sbjct: 162 YQCLAENKYGAIYASAELKI----------------------LASAPTFALNQLKKTII- 198
Query: 1532 ERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +++ V E G+P P I W K ++ +R ++R I + I A+K EG
Sbjct: 199 --VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD---GSLRILNASKSDEG 253
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
Y C+ + G A A L V
Sbjct: 254 KYVCRGENVFGSAEIIASLSV 274
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/259 (26%), Positives = 110/259 (42%), Gaps = 39/259 (15%)
Query: 1235 KALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
K+ VLE N+ D G+ CRAEN G S G V P + L +T +
Sbjct: 55 KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQL 107
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
G + CK G+P P W N + + +G+ IH AG+Y
Sbjct: 108 DSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV---EMVNGVLMIH--NVNQSDAGMY 162
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+C A N++G + + +E +L+ T FA +K T++ T
Sbjct: 163 QCLAENKYGA--------------IYASAELKILASAPT-----FALNQLK--KTIIVTK 201
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ +++ +E K G PKP + W ++G ++ + +I L DG+ L + + D G+ V
Sbjct: 202 DQEVV-IECKPQGSPKPTISW-KKGDRAVRENK-RIAILPDGS--LRILNASKSDEGKYV 256
Query: 1474 FEAYNHLGVTATIAALSVE 1492
N G IA+LSV+
Sbjct: 257 CRGENVFGSAEIIASLSVK 275
Score = 43.6 bits (98), Expect = 0.007
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 13/117 (11%)
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
E+ P+I P VT +G +++E A+G P P + W++ + L
Sbjct: 3 EYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-----RLRKSQ 57
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
++L +P V DD G A N G + L V Y P WV + + Q
Sbjct: 58 AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV--------YTYPHWVEKLNDTQ 106
Score = 39.9 bits (89), Expect = 0.087
Identities = 37/157 (23%), Positives = 64/157 (40%), Gaps = 12/157 (7%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGD 1280
K+ L+P+ + ++ N+++ G+ C AEN G++ S E +
Sbjct: 131 KNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASA-----ELKILASA 185
Query: 1281 APLVLAPLENTTVMDGER-ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
L L+ T ++ ++ + + CK G P P I W ++ + + I I S
Sbjct: 186 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGS---- 241
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+ I A G Y C N FG S E I ++ E
Sbjct: 242 LRILNASKSDEGKYVCRGENVFG--SAEIIASLSVKE 276
Score = 35.9 bits (79), Expect = 1.4
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V E GNP P I W K N I + R ++++ I D G Y C+A +
Sbjct: 24 VKMECFALGNPVPTITWMKVNGYIPSKARL----RKSQAVLEIPNVQLDDAGIYECRAEN 79
Query: 1600 DIGLAVTKAKLQVF 1613
G + +LQV+
Sbjct: 80 SRGKNSFRGQLQVY 93
Score = 34.7 bits (76), Expect = 3.3
Identities = 29/76 (38%), Positives = 36/76 (47%), Gaps = 9/76 (11%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLEN 1290
I P +L +L N SK G CR EN GS S V+E T I+ L P +
Sbjct: 236 ILPDGSLRIL--NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE------LTP-KR 286
Query: 1291 TTVMDGERISLNCKIL 1306
T + GE I LNCK +
Sbjct: 287 TELTVGESIVLNCKAI 302
>BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth factor
receptor-like 1 protein.
Length = 504
Score = 58.0 bits (134), Expect = 3e-07
Identities = 53/217 (24%), Positives = 96/217 (44%), Gaps = 14/217 (6%)
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
K +P V G+ +RL+ G P P W + G + S + L G L + +
Sbjct: 34 KVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQG---LKVKQ 88
Query: 1464 VYQDDTGEIVFEAYNHLG-VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSV 1522
V ++D G V +A N G ++ + ++ I +E P+ + +E A+ + +
Sbjct: 89 VEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWAR-- 146
Query: 1523 PTFVKEI-IPERVHEEEI---VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P F + + RV + V + + SG+P P+I W KD++ + E E ++ +
Sbjct: 147 PRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPE--AAEPRKKKW 204
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
T ++K + G YTC+ + G K+ V QR
Sbjct: 205 TLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQR 241
Score = 52.0 bits (119), Expect = 2e-05
Identities = 73/324 (22%), Positives = 125/324 (38%), Gaps = 19/324 (5%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G + L C + G P P W + + I + SR + + +K+ E AG+Y C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGW----SRFRVLPQGLKVKQVEREDAGVYVC 99
Query: 1356 TASNQFGKCSTECILNI--EAYEYVPSVSEEDVLSDEKTSDVEEFA-PRIV---KALPTV 1409
A+N FG S L + + S+ + ++ +++A PR K V
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRV 159
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G +RL+ A G P+P + W++ L T + E L++ + +D+
Sbjct: 160 IARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDS 216
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWV-THMEELQAALKATQSVPTFVKE 1528
G+ N G A A V+ I T+ KP TH T S V+
Sbjct: 217 GKYTCRVSNRAG--AINATYKVDVIQRTRS--KPVLTGTHPVNTTVDFGGTTSFQCKVRS 272
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ + + V + A N T ++ K V+ T + + + I +A +D
Sbjct: 273 DVKPVIQWLKRVEYGAEGRHNSTIDVGGQK-FVVLPTGDVWSRPDGSYLNKLLITRARQD 331
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
G Y C + +G + A L V
Sbjct: 332 DAGMYICLGANTMGYSFRSAFLTV 355
Score = 35.1 bits (77), Expect = 2.5
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 1221 KDSTELT-PRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID 1278
KD LT P +P K L +N+ + G TCR N AG+++ + V ++T
Sbjct: 186 KDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--- 242
Query: 1279 GDAPLVLAPLE-NTTVMDGERISLNCKILGRPWPKIDW 1315
P++ NTTV G S CK+ P I W
Sbjct: 243 RSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQW 280
>AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein.
Length = 504
Score = 58.0 bits (134), Expect = 3e-07
Identities = 53/217 (24%), Positives = 96/217 (44%), Gaps = 14/217 (6%)
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
K +P V G+ +RL+ G P P W + G + S + L G L + +
Sbjct: 34 KVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQG---LKVKQ 88
Query: 1464 VYQDDTGEIVFEAYNHLG-VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSV 1522
V ++D G V +A N G ++ + ++ I +E P+ + +E A+ + +
Sbjct: 89 VEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWAR-- 146
Query: 1523 PTFVKEI-IPERVHEEEI---VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P F + + RV + V + + SG+P P+I W KD++ + E E ++ +
Sbjct: 147 PRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPE--AAEPRKKKW 204
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
T ++K + G YTC+ + G K+ V QR
Sbjct: 205 TLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQR 241
Score = 52.0 bits (119), Expect = 2e-05
Identities = 73/324 (22%), Positives = 125/324 (38%), Gaps = 19/324 (5%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G + L C + G P P W + + I + SR + + +K+ E AG+Y C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGW----SRFRVLPQGLKVKQVEREDAGVYVC 99
Query: 1356 TASNQFGKCSTECILNI--EAYEYVPSVSEEDVLSDEKTSDVEEFA-PRIV---KALPTV 1409
A+N FG S L + + S+ + ++ +++A PR K V
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRV 159
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G +RL+ A G P+P + W++ L T + E L++ + +D+
Sbjct: 160 IARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDS 216
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWV-THMEELQAALKATQSVPTFVKE 1528
G+ N G A A V+ I T+ KP TH T S V+
Sbjct: 217 GKYTCRVSNRAG--AINATYKVDVIQRTRS--KPVLTGTHPVNTTVDFGGTTSFQCKVRS 272
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ + + V + A N T ++ K V+ T + + + I +A +D
Sbjct: 273 DVKPVIQWLKRVEYGAEGRHNSTIDVGGQK-FVVLPTGDVWSRPDGSYLNKLLITRARQD 331
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
G Y C + +G + A L V
Sbjct: 332 DAGMYICLGANTMGYSFRSAFLTV 355
Score = 35.1 bits (77), Expect = 2.5
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 1221 KDSTELT-PRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID 1278
KD LT P +P K L +N+ + G TCR N AG+++ + V ++T
Sbjct: 186 KDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--- 242
Query: 1279 GDAPLVLAPLE-NTTVMDGERISLNCKILGRPWPKIDW 1315
P++ NTTV G S CK+ P I W
Sbjct: 243 RSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQW 280
>AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens cDNA
FLJ23990 fis, clone HRC08053, highly similar to Homo
sapiens fibroblast growth factor receptor-like 1
(FGFRL1). ).
Length = 440
Score = 58.0 bits (134), Expect = 3e-07
Identities = 53/217 (24%), Positives = 96/217 (44%), Gaps = 14/217 (6%)
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
K +P V G+ +RL+ G P P W + G + S + L G L + +
Sbjct: 4 KVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQG---LKVKQ 58
Query: 1464 VYQDDTGEIVFEAYNHLG-VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSV 1522
V ++D G V +A N G ++ + ++ I +E P+ + +E A+ + +
Sbjct: 59 VEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWAR-- 116
Query: 1523 PTFVKEI-IPERVHEEEI---VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P F + + RV + V + + SG+P P+I W KD++ + E E ++ +
Sbjct: 117 PRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPE--AAEPRKKKW 174
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
T ++K + G YTC+ + G K+ V QR
Sbjct: 175 TLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQR 211
Score = 52.0 bits (119), Expect = 2e-05
Identities = 73/324 (22%), Positives = 125/324 (38%), Gaps = 19/324 (5%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G + L C + G P P W + + I + SR + + +K+ E AG+Y C
Sbjct: 14 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGW----SRFRVLPQGLKVKQVEREDAGVYVC 69
Query: 1356 TASNQFGKCSTECILNI--EAYEYVPSVSEEDVLSDEKTSDVEEFA-PRIV---KALPTV 1409
A+N FG S L + + S+ + ++ +++A PR K V
Sbjct: 70 KATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRV 129
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G +RL+ A G P+P + W++ L T + E L++ + +D+
Sbjct: 130 IARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDS 186
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWV-THMEELQAALKATQSVPTFVKE 1528
G+ N G A A V+ I T+ KP TH T S V+
Sbjct: 187 GKYTCRVSNRAG--AINATYKVDVIQRTRS--KPVLTGTHPVNTTVDFGGTTSFQCKVRS 242
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ + + V + A N T ++ K V+ T + + + I +A +D
Sbjct: 243 DVKPVIQWLKRVEYGAEGRHNSTIDVGGQK-FVVLPTGDVWSRPDGSYLNKLLITRARQD 301
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
G Y C + +G + A L V
Sbjct: 302 DAGMYICLGANTMGYSFRSAFLTV 325
Score = 35.1 bits (77), Expect = 2.5
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 1221 KDSTELT-PRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID 1278
KD LT P +P K L +N+ + G TCR N AG+++ + V ++T
Sbjct: 156 KDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--- 212
Query: 1279 GDAPLVLAPLE-NTTVMDGERISLNCKILGRPWPKIDW 1315
P++ NTTV G S CK+ P I W
Sbjct: 213 RSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQW 250
>AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein.
Length = 504
Score = 58.0 bits (134), Expect = 3e-07
Identities = 53/217 (24%), Positives = 96/217 (44%), Gaps = 14/217 (6%)
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
K +P V G+ +RL+ G P P W + G + S + L G L + +
Sbjct: 34 KVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQG---LKVKQ 88
Query: 1464 VYQDDTGEIVFEAYNHLG-VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSV 1522
V ++D G V +A N G ++ + ++ I +E P+ + +E A+ + +
Sbjct: 89 VEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWAR-- 146
Query: 1523 PTFVKEI-IPERVHEEEI---VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P F + + RV + V + + SG+P P+I W KD++ + E E ++ +
Sbjct: 147 PRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPE--AAEPRKKKW 204
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
T ++K + G YTC+ + G K+ V QR
Sbjct: 205 TLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQR 241
Score = 52.0 bits (119), Expect = 2e-05
Identities = 73/324 (22%), Positives = 125/324 (38%), Gaps = 19/324 (5%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G + L C + G P P W + + I + SR + + +K+ E AG+Y C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGW----SRFRVLPQGLKVKQVEREDAGVYVC 99
Query: 1356 TASNQFGKCSTECILNI--EAYEYVPSVSEEDVLSDEKTSDVEEFA-PRIV---KALPTV 1409
A+N FG S L + + S+ + ++ +++A PR K V
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRV 159
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G +RL+ A G P+P + W++ L T + E L++ + +D+
Sbjct: 160 IARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDS 216
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWV-THMEELQAALKATQSVPTFVKE 1528
G+ N G A A V+ I T+ KP TH T S V+
Sbjct: 217 GKYTCRVSNRAG--AINATYKVDVIQRTRS--KPVLTGTHPVNTTVDFGGTTSFQCKVRS 272
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ + + V + A N T ++ K V+ T + + + I +A +D
Sbjct: 273 DVKPVIQWLKRVEYGAEGRHNSTIDVGGQK-FVVLPTGDVWSRPDGSYLNKLLITRARQD 331
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
G Y C + +G + A L V
Sbjct: 332 DAGMYICLGANTMGYSFRSAFLTV 355
Score = 35.1 bits (77), Expect = 2.5
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 1221 KDSTELT-PRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID 1278
KD LT P +P K L +N+ + G TCR N AG+++ + V ++T
Sbjct: 186 KDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--- 242
Query: 1279 GDAPLVLAPLE-NTTVMDGERISLNCKILGRPWPKIDW 1315
P++ NTTV G S CK+ P I W
Sbjct: 243 RSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQW 280
>AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor
receptor protein.
Length = 497
Score = 58.0 bits (134), Expect = 3e-07
Identities = 53/217 (24%), Positives = 96/217 (44%), Gaps = 14/217 (6%)
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
K +P V G+ +RL+ G P P W + G + S + L G L + +
Sbjct: 34 KVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQG---LKVKQ 88
Query: 1464 VYQDDTGEIVFEAYNHLG-VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSV 1522
V ++D G V +A N G ++ + ++ I +E P+ + +E A+ + +
Sbjct: 89 VEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWAR-- 146
Query: 1523 PTFVKEI-IPERVHEEEI---VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P F + + RV + V + + SG+P P+I W KD++ + E E ++ +
Sbjct: 147 PRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPE--AAEPRKKKW 204
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
T ++K + G YTC+ + G K+ V QR
Sbjct: 205 TLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQR 241
Score = 52.0 bits (119), Expect = 2e-05
Identities = 73/324 (22%), Positives = 125/324 (38%), Gaps = 19/324 (5%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G + L C + G P P W + + I + SR + + +K+ E AG+Y C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGW----SRFRVLPQGLKVKQVEREDAGVYVC 99
Query: 1356 TASNQFGKCSTECILNI--EAYEYVPSVSEEDVLSDEKTSDVEEFA-PRIV---KALPTV 1409
A+N FG S L + + S+ + ++ +++A PR K V
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRV 159
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G +RL+ A G P+P + W++ L T + E L++ + +D+
Sbjct: 160 IARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDS 216
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWV-THMEELQAALKATQSVPTFVKE 1528
G+ N G A A V+ I T+ KP TH T S V+
Sbjct: 217 GKYTCRVSNRAG--AINATYKVDVIQRTRS--KPVLTGTHPVNTTVDFGGTTSFQCKVRS 272
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ + + V + A N T ++ K V+ T + + + I +A +D
Sbjct: 273 DVKPVIQWLKRVEYGAEGRHNSTIDVGGQK-FVVLPTGDVWSRPDGSYLNKLLITRARQD 331
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
G Y C + +G + A L V
Sbjct: 332 DAGMYICLGANTMGYSFRSAFLTV 355
Score = 35.1 bits (77), Expect = 2.5
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 1221 KDSTELT-PRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID 1278
KD LT P +P K L +N+ + G TCR N AG+++ + V ++T
Sbjct: 186 KDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--- 242
Query: 1279 GDAPLVLAPLE-NTTVMDGERISLNCKILGRPWPKIDW 1315
P++ NTTV G S CK+ P I W
Sbjct: 243 RSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQW 280
>AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth factor
receptor 5 protein.
Length = 504
Score = 58.0 bits (134), Expect = 3e-07
Identities = 53/217 (24%), Positives = 96/217 (44%), Gaps = 14/217 (6%)
Query: 1404 KALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
K +P V G+ +RL+ G P P W + G + S + L G L + +
Sbjct: 34 KVVPRQVARL-GRTVRLQCPVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQG---LKVKQ 88
Query: 1464 VYQDDTGEIVFEAYNHLG-VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSV 1522
V ++D G V +A N G ++ + ++ I +E P+ + +E A+ + +
Sbjct: 89 VEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWAR-- 146
Query: 1523 PTFVKEI-IPERVHEEEI---VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
P F + + RV + V + + SG+P P+I W KD++ + E E ++ +
Sbjct: 147 PRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPE--AAEPRKKKW 204
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
T ++K + G YTC+ + G K+ V QR
Sbjct: 205 TLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQR 241
Score = 52.0 bits (119), Expect = 2e-05
Identities = 73/324 (22%), Positives = 125/324 (38%), Gaps = 19/324 (5%)
Query: 1296 GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKC 1355
G + L C + G P P W + + I + SR + + +K+ E AG+Y C
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGW----SRFRVLPQGLKVKQVEREDAGVYVC 99
Query: 1356 TASNQFGKCSTECILNI--EAYEYVPSVSEEDVLSDEKTSDVEEFA-PRIV---KALPTV 1409
A+N FG S L + + S+ + ++ +++A PR K V
Sbjct: 100 KATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRV 159
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+ G +RL+ A G P+P + W++ L T + E L++ + +D+
Sbjct: 160 IARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDS 216
Query: 1470 GEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWV-THMEELQAALKATQSVPTFVKE 1528
G+ N G A A V+ I T+ KP TH T S V+
Sbjct: 217 GKYTCRVSNRAG--AINATYKVDVIQRTRS--KPVLTGTHPVNTTVDFGGTTSFQCKVRS 272
Query: 1529 IIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKD 1588
+ + + V + A N T ++ K V+ T + + + I +A +D
Sbjct: 273 DVKPVIQWLKRVEYGAEGRHNSTIDVGGQK-FVVLPTGDVWSRPDGSYLNKLLITRARQD 331
Query: 1589 LEGTYTCKAVSDIGLAVTKAKLQV 1612
G Y C + +G + A L V
Sbjct: 332 DAGMYICLGANTMGYSFRSAFLTV 355
Score = 35.1 bits (77), Expect = 2.5
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 1221 KDSTELT-PRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCID 1278
KD LT P +P K L +N+ + G TCR N AG+++ + V ++T
Sbjct: 186 KDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRT--- 242
Query: 1279 GDAPLVLAPLE-NTTVMDGERISLNCKILGRPWPKIDW 1315
P++ NTTV G S CK+ P I W
Sbjct: 243 RSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQW 280
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 58.0 bits (134), Expect = 3e-07
Identities = 81/321 (25%), Positives = 119/321 (37%), Gaps = 63/321 (19%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T G + + C LG P P I W I + +R + + I + AG
Sbjct: 237 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSK-----ARLRKSQAVLEIPNVQLDDAG 291
Query: 1352 IYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVT 1411
IY+C A N GK S L + Y + EK +D +
Sbjct: 292 IYECRAENSRGKNSFRGQLQVYTYPHWV----------EKLNDTQ--------------- 326
Query: 1412 TTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE 1471
G +R E KA G P+P RWL+ G L S + ++E ++ +L + V Q D G
Sbjct: 327 LDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVEMVN---GVLMIHNVNQSDAGM 381
Query: 1472 IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP 1531
A N G A L + A T ++ K II
Sbjct: 382 YQCLAENKYGAIYASAELKI----------------------LASAPTFALNQLKKTII- 418
Query: 1532 ERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +++ V E G+P P I W K ++ +R ++R I + I A+K EG
Sbjct: 419 --VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD---GSLRILNASKSDEG 473
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
Y C+ + G A A L V
Sbjct: 474 KYVCRGENVFGSAEIIASLSV 494
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/259 (26%), Positives = 110/259 (42%), Gaps = 39/259 (15%)
Query: 1235 KALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
K+ VLE N+ D G+ CRAEN G S G V P + L +T +
Sbjct: 275 KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQL 327
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
G + CK G+P P W N + + +G+ IH AG+Y
Sbjct: 328 DSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV---EMVNGVLMIH--NVNQSDAGMY 382
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+C A N++G + + +E +L+ T FA +K T++ T
Sbjct: 383 QCLAENKYGA--------------IYASAELKILASAPT-----FALNQLK--KTIIVTK 421
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ +++ +E K G PKP + W ++G ++ + +I L DG+ L + + D G+ V
Sbjct: 422 DQEVV-IECKPQGSPKPTISW-KKGDRAVRENK-RIAILPDGS--LRILNASKSDEGKYV 476
Query: 1474 FEAYNHLGVTATIAALSVE 1492
N G IA+LSV+
Sbjct: 477 CRGENVFGSAEIIASLSVK 495
Score = 43.6 bits (98), Expect = 0.007
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 13/117 (11%)
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
E+ P+I P VT +G +++E A+G P P + W++ + L
Sbjct: 223 EYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-----RLRKSQ 277
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
++L +P V DD G A N G + L V Y P WV + + Q
Sbjct: 278 AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV--------YTYPHWVEKLNDTQ 326
Score = 43.2 bits (97), Expect = 0.009
Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 1393 SDVEEFAPRIVKALPTVV--TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
S+ ++ P V+ ++ T ++ K + L + G P P RWLR GTE+ ++Y+
Sbjct: 18 SESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRY- 76
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
L DGT I++ P + D+G A N +G
Sbjct: 77 SLIDGTFIISNPSEAK-DSGHYQCLATNTVG 106
Score = 39.9 bits (89), Expect = 0.087
Identities = 37/157 (23%), Positives = 64/157 (40%), Gaps = 12/157 (7%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGD 1280
K+ L+P+ + ++ N+++ G+ C AEN G++ S E +
Sbjct: 351 KNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASA-----ELKILASA 405
Query: 1281 APLVLAPLENTTVMDGER-ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
L L+ T ++ ++ + + CK G P P I W ++ + + I I S
Sbjct: 406 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGS---- 461
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+ I A G Y C N FG S E I ++ E
Sbjct: 462 LRILNASKSDEGKYVCRGENVFG--SAEIIASLSVKE 496
Score = 36.7 bits (81), Expect = 0.81
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T D ++++LNC++ G P P W N I+ D S + EA + +G
Sbjct: 38 TDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEA--KDSG 95
Query: 1352 IYKCTASNQFG 1362
Y+C A+N G
Sbjct: 96 HYQCLATNTVG 106
Score = 35.9 bits (79), Expect = 1.4
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V E GNP P I W K N I + R ++++ I D G Y C+A +
Sbjct: 244 VKMECFALGNPVPTITWMKVNGYIPSKARL----RKSQAVLEIPNVQLDDAGIYECRAEN 299
Query: 1600 DIGLAVTKAKLQVF 1613
G + +LQV+
Sbjct: 300 SRGKNSFRGQLQVY 313
Score = 34.7 bits (76), Expect = 3.3
Identities = 29/76 (38%), Positives = 36/76 (47%), Gaps = 9/76 (11%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLEN 1290
I P +L +L N SK G CR EN GS S V+E T I+ L P +
Sbjct: 456 ILPDGSLRIL--NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE------LTP-KR 506
Query: 1291 TTVMDGERISLNCKIL 1306
T + GE I LNCK +
Sbjct: 507 TELTVGESIVLNCKAI 522
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 58.0 bits (134), Expect = 3e-07
Identities = 81/321 (25%), Positives = 119/321 (37%), Gaps = 63/321 (19%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T G + + C LG P P I W I + +R + + I + AG
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSK-----ARLRKSQAVLEIPNVQLDDAG 365
Query: 1352 IYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVT 1411
IY+C A N GK S L + Y + EK +D +
Sbjct: 366 IYECRAENSRGKNSFRGQLQVYTYPHWV----------EKLNDTQ--------------- 400
Query: 1412 TTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE 1471
G +R E KA G P+P RWL+ G L S + ++E ++ +L + V Q D G
Sbjct: 401 LDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVEMVN---GVLMIHNVNQSDAGM 455
Query: 1472 IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIP 1531
A N G A L + A T ++ K II
Sbjct: 456 YQCLAENKYGAIYASAELKI----------------------LASAPTFALNQLKKTII- 492
Query: 1532 ERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +++ V E G+P P I W K ++ +R ++R I + I A+K EG
Sbjct: 493 --VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPD---GSLRILNASKSDEG 547
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
Y C+ + G A A L V
Sbjct: 548 KYVCRGENVFGSAEIIASLSV 568
Score = 57.2 bits (132), Expect = 5e-07
Identities = 68/259 (26%), Positives = 110/259 (42%), Gaps = 39/259 (15%)
Query: 1235 KALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
K+ VLE N+ D G+ CRAEN G S G V P + L +T +
Sbjct: 349 KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY-------PHWVEKLNDTQL 401
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
G + CK G+P P W N + + +G+ IH AG+Y
Sbjct: 402 DSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV---EMVNGVLMIH--NVNQSDAGMY 456
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+C A N++G + + +E +L+ T FA +K T++ T
Sbjct: 457 QCLAENKYGA--------------IYASAELKILASAPT-----FALNQLK--KTIIVTK 495
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
+ +++ +E K G PKP + W ++G ++ + +I L DG+ L + + D G+ V
Sbjct: 496 DQEVV-IECKPQGSPKPTISW-KKGDRAVRENK-RIAILPDGS--LRILNASKSDEGKYV 550
Query: 1474 FEAYNHLGVTATIAALSVE 1492
N G IA+LSV+
Sbjct: 551 CRGENVFGSAEIIASLSVK 569
Score = 43.6 bits (98), Expect = 0.007
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 13/117 (11%)
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGT 1456
E+ P+I P VT +G +++E A+G P P + W++ + L
Sbjct: 297 EYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-----RLRKSQ 351
Query: 1457 SILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQ 1513
++L +P V DD G A N G + L V Y P WV + + Q
Sbjct: 352 AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV--------YTYPHWVEKLNDTQ 400
Score = 43.2 bits (97), Expect = 0.009
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
Query: 1391 KTSDVEEFAPRIVKALPTVV--TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
K + ++ P V+ ++ T ++ K + L + G P P RWLR GTE+ ++Y+
Sbjct: 90 KQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYR 149
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
L DGT I++ P + D+G A N +G
Sbjct: 150 Y-SLIDGTFIISNPSEAK-DSGHYQCLATNTVG 180
Score = 39.9 bits (89), Expect = 0.087
Identities = 37/157 (23%), Positives = 64/157 (40%), Gaps = 12/157 (7%)
Query: 1221 KDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGD 1280
K+ L+P+ + ++ N+++ G+ C AEN G++ S E +
Sbjct: 425 KNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASA-----ELKILASA 479
Query: 1281 APLVLAPLENTTVMDGER-ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
L L+ T ++ ++ + + CK G P P I W ++ + + I I S
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGS---- 535
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+ I A G Y C N FG S E I ++ E
Sbjct: 536 LRILNASKSDEGKYVCRGENVFG--SAEIIASLSVKE 570
Score = 36.7 bits (81), Expect = 0.81
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T D ++++LNC++ G P P W N I+ D S + EA + +G
Sbjct: 112 TDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEA--KDSG 169
Query: 1352 IYKCTASNQFG 1362
Y+C A+N G
Sbjct: 170 HYQCLATNTVG 180
Score = 35.9 bits (79), Expect = 1.4
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
V E GNP P I W K N I + R ++++ I D G Y C+A +
Sbjct: 318 VKMECFALGNPVPTITWMKVNGYIPSKARL----RKSQAVLEIPNVQLDDAGIYECRAEN 373
Query: 1600 DIGLAVTKAKLQVF 1613
G + +LQV+
Sbjct: 374 SRGKNSFRGQLQVY 387
Score = 34.7 bits (76), Expect = 3.3
Identities = 29/76 (38%), Positives = 36/76 (47%), Gaps = 9/76 (11%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLEN 1290
I P +L +L N SK G CR EN GS S V+E T I+ L P +
Sbjct: 530 ILPDGSLRIL--NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE------LTP-KR 580
Query: 1291 TTVMDGERISLNCKIL 1306
T + GE I LNCK +
Sbjct: 581 TELTVGESIVLNCKAI 596
>X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein.
Length = 1138
Score = 57.6 bits (133), Expect = 4e-07
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
+AP+ PL N G +LNC + G P PKI W N+ +++ R S G+C
Sbjct: 1042 EAPMFTQPLVNRLCHSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NLGVC 1099
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ I + P G Y C A N G EC L ++
Sbjct: 1100 TLEIGKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1134
Score = 56.0 bits (129), Expect = 1e-06
Identities = 29/90 (32%), Positives = 43/90 (47%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F + ++ H + T GNP P+I W K+ I D R+ + + T I
Sbjct: 1044 PMFTQPLVNRLCHSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNLGVCTLEI 1103
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
K + GTY CKAV+D+G + KL+V
Sbjct: 1104 GKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1133
Score = 37.9 bits (84), Expect = 0.35
Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 3/93 (3%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P +K+ RV + I+ + G P PE+ W KD I ++ I N E T I
Sbjct: 840 PKHLKQTYIRRVGDRVILVIP--FQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFI 896
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+KA + G Y + D + +++ R
Sbjct: 897 RKAERSHSGKYDLQVKVDKFVETASIDIRIIDR 929
Score = 34.3 bits (75), Expect = 4.3
Identities = 21/99 (21%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 1239 VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGER 1298
+ E+ + ++ + C+ + + T+G + + +V LE+TT GER
Sbjct: 298 IFEDTRCQSILNIDNCQMTDDSEYYVTAGDEKCSTELLVREPPIMVTKQLEDTTDYCGER 357
Query: 1299 ISLNCKILGRPWPKIDWFHNEK---LIETARDITISRQK 1334
+ L C++ ++ WF N + L++T I + +K
Sbjct: 358 VELECEV-SEDDAQVKWFKNGEEIILVQTRYRIRVEGKK 395
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 57.6 bits (133), Expect = 4e-07
Identities = 83/351 (23%), Positives = 135/351 (38%), Gaps = 66/351 (18%)
Query: 1262 SVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKL 1321
+VS +G+ + Q + D P L P N TV GE L+C++LG + W + ++
Sbjct: 461 AVSRAGTGRAKAQIVVT-DPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRV 519
Query: 1322 IETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSV 1381
+ + Q + L + I P G Y+C ASN G L + P V
Sbjct: 520 LPASTGRV--AQLADL-SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVRE---APQV 573
Query: 1382 SEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
S TS + F ++G +++ A G P P + W R+ L
Sbjct: 574 SIH-------TSS-QHF--------------SQGVEVKVSCSASGYPTPHISWSRESQAL 611
Query: 1442 LQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYR 1501
+ + + D L + V +D G +A N +G E++ T Y
Sbjct: 612 QEDSRIHV----DAQGTLIIQGVAPEDAGNYSCQATNEVGT-------DQETV--TLYYT 658
Query: 1502 KPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNK 1561
P V + V ++ V EE ++ EA SG P P ++WY+
Sbjct: 659 DPPSV-----------------SAVNAVVLVAVGEEAVLVCEA--SGVPPPRVIWYRGGL 699
Query: 1562 VIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
E + + I A + GTYTC+AV+++G A + +L V
Sbjct: 700 -----EMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745
Score = 38.7 bits (86), Expect = 0.20
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 6/123 (4%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
GV A N++ + + E T D P V A V GE L C+ G P
Sbjct: 629 GVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVP 688
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P++ W+ ++ ++ + S ++ I A AG Y C A N+ G S E
Sbjct: 689 PPRVIWYRG------GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQ 742
Query: 1370 LNI 1372
L +
Sbjct: 743 LAV 745
>U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H
protein.
Length = 477
Score = 56.8 bits (131), Expect = 7e-07
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIE-TARDITISRQKSGLC 1338
+AP PL + T G L C + P PKI W N+ I+ + +S Q G+C
Sbjct: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQ--GVC 437
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
+ I++ P +G+Y C A N G+ S +C L ++A
Sbjct: 438 TLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
Score = 42.7 bits (96), Expect = 0.012
Identities = 19/64 (29%), Positives = 37/64 (57%)
Query: 1549 NPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
+P P+I+W K+ I+ + ++ +++ T I+K + G YTCKA++ +G A
Sbjct: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDC 467
Query: 1609 KLQV 1612
+L+V
Sbjct: 468 RLEV 471
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 56.8 bits (131), Expect = 7e-07
Identities = 78/344 (22%), Positives = 124/344 (36%), Gaps = 60/344 (17%)
Query: 1272 EEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITIS 1331
EE C + P + + ++ V G + C+ G P P+I W N + D ++
Sbjct: 256 EELNC---ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLN 312
Query: 1332 RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
G I + + GIY+C A N G+ T+ + Y S + + +
Sbjct: 313 LLDDGTLMIQNTQETDQ--GIYQCMAKNVAGEVKTQEV----TLRYFGSPARPTFVIQPQ 366
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE 1451
++V G+ + LE A G P P++ W R G + ++
Sbjct: 367 NTEV-----------------LVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRVNI 408
Query: 1452 LDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEE 1511
G L + V Q D+GE A N+ ++S+ T
Sbjct: 409 TPSGG--LYIQNVVQGDSGEYACSATNN-----------IDSVHAT-------------- 441
Query: 1512 LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII 1571
A Q++P F V E + V F+ GNP P I W K + D R ++
Sbjct: 442 ---AFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLV 498
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ T I +G Y C+AV+ IG A L V R
Sbjct: 499 LSS---GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR 539
Score = 54.4 bits (125), Expect = 4e-06
Identities = 62/275 (22%), Positives = 113/275 (41%), Gaps = 38/275 (13%)
Query: 1221 KDSTELTPRIIQPLKALN---VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
+++ EL+ + L L+ ++ +N + G+ C A+N AG V T +
Sbjct: 298 RNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQ--EVTLRYFGS 355
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
V+ P +NT V+ GE ++L C G P P+I W ++ D ++ SG
Sbjct: 356 PARPTFVIQP-QNTEVLVGESVTLECSATGHPPPRISWTRGDR-TPLPVDPRVNITPSG- 412
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE 1397
++I+ +G Y C+A+N + ++A ++ V+ + +T D
Sbjct: 413 -GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVD--- 468
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
+ EAK G P P + W + G++L + + L GT
Sbjct: 469 --------------------FQCEAK--GNPPPVIAWTKGGSQLSVDRRHLV--LSSGT- 503
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
L + V D G+ +A N +G +A L+V+
Sbjct: 504 -LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 537
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 13/133 (9%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C+A N GS +V T P+ + +TTV G + L C G P
Sbjct: 515 GQYECQAVNIIGS-----QKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEP 569
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W N+ ++ G + I + P AG Y+C A N G S +
Sbjct: 570 EPAITW--NKDGVQVTESGKFHISPEGF--LTINDVGPADAGRYECVARNTIGSASVSMV 625
Query: 1370 LNIEAYEYVPSVS 1382
L++ VP VS
Sbjct: 626 LSVN----VPDVS 634
Score = 41.9 bits (94), Expect = 0.022
Identities = 60/266 (22%), Positives = 101/266 (37%), Gaps = 43/266 (16%)
Query: 1228 PRI-IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLA 1286
PR+ I P L + +N+ + G C A N SV + IV+ P
Sbjct: 404 PRVNITPSGGLYI--QNVVQGDSGEYACSATNNIDSVHATAFIIVQA-------LPQFTV 454
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEA 1345
++ V++G+ + C+ G P P I W +L R + +S SG + I
Sbjct: 455 TPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLS---SGT--LRISGV 509
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
G Y+C A N G L ++ P V+ + +
Sbjct: 510 ALHDQGQYECQAVNIIGSQKVVAHLTVQ-----PRVTP------------------VFAS 546
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+P+ T G ++L + G P+P + W + G ++ +S ++ I LT+ +V
Sbjct: 547 IPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISP----EGFLTINDVG 602
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSV 1491
D G A N +G + LSV
Sbjct: 603 PADAGRYECVARNTIGSASVSMVLSV 628
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 56.8 bits (131), Expect = 7e-07
Identities = 78/344 (22%), Positives = 124/344 (36%), Gaps = 60/344 (17%)
Query: 1272 EEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITIS 1331
EE C + P + + ++ V G + C+ G P P+I W N + D ++
Sbjct: 234 EELNC---ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLN 290
Query: 1332 RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
G I + + GIY+C A N G+ T+ + Y S + + +
Sbjct: 291 LLDDGTLMIQNTQETDQ--GIYQCMAKNVAGEVKTQEV----TLRYFGSPARPTFVIQPQ 344
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE 1451
++V G+ + LE A G P P++ W R G + ++
Sbjct: 345 NTEV-----------------LVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRVNI 386
Query: 1452 LDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEE 1511
G L + V Q D+GE A N+ ++S+ T
Sbjct: 387 TPSGG--LYIQNVVQGDSGEYACSATNN-----------IDSVHAT-------------- 419
Query: 1512 LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII 1571
A Q++P F V E + V F+ GNP P I W K + D R ++
Sbjct: 420 ---AFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLV 476
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ T I +G Y C+AV+ IG A L V R
Sbjct: 477 LSS---GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR 517
Score = 54.4 bits (125), Expect = 4e-06
Identities = 62/275 (22%), Positives = 113/275 (41%), Gaps = 38/275 (13%)
Query: 1221 KDSTELTPRIIQPLKALN---VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
+++ EL+ + L L+ ++ +N + G+ C A+N AG V T +
Sbjct: 276 RNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQ--EVTLRYFGS 333
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
V+ P +NT V+ GE ++L C G P P+I W ++ D ++ SG
Sbjct: 334 PARPTFVIQP-QNTEVLVGESVTLECSATGHPPPRISWTRGDR-TPLPVDPRVNITPSG- 390
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE 1397
++I+ +G Y C+A+N + ++A ++ V+ + +T D
Sbjct: 391 -GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVD--- 446
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
+ EAK G P P + W + G++L + + L GT
Sbjct: 447 --------------------FQCEAK--GNPPPVIAWTKGGSQLSVDRRHLV--LSSGT- 481
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
L + V D G+ +A N +G +A L+V+
Sbjct: 482 -LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 515
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 13/133 (9%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C+A N GS +V T P+ + +TTV G + L C G P
Sbjct: 493 GQYECQAVNIIGS-----QKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEP 547
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W N+ ++ G + I + P AG Y+C A N G S +
Sbjct: 548 EPAITW--NKDGVQVTESGKFHISPEGF--LTINDVGPADAGRYECVARNTIGSASVSMV 603
Query: 1370 LNIEAYEYVPSVS 1382
L++ VP VS
Sbjct: 604 LSVN----VPDVS 612
Score = 41.9 bits (94), Expect = 0.022
Identities = 60/266 (22%), Positives = 101/266 (37%), Gaps = 43/266 (16%)
Query: 1228 PRI-IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLA 1286
PR+ I P L + +N+ + G C A N SV + IV+ P
Sbjct: 382 PRVNITPSGGLYI--QNVVQGDSGEYACSATNNIDSVHATAFIIVQA-------LPQFTV 432
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEA 1345
++ V++G+ + C+ G P P I W +L R + +S SG + I
Sbjct: 433 TPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLS---SGT--LRISGV 487
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
G Y+C A N G L ++ P V+ + +
Sbjct: 488 ALHDQGQYECQAVNIIGSQKVVAHLTVQ-----PRVTP------------------VFAS 524
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+P+ T G ++L + G P+P + W + G ++ +S ++ I LT+ +V
Sbjct: 525 IPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISP----EGFLTINDVG 580
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSV 1491
D G A N +G + LSV
Sbjct: 581 PADAGRYECVARNTIGSASVSMVLSV 606
>BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein H
protein.
Length = 477
Score = 56.8 bits (131), Expect = 7e-07
Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIE-TARDITISRQKSGLC 1338
+AP PL + T G L C + P PKI W N+ I+ + +S Q G+C
Sbjct: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQ--GVC 437
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEA 1374
+ I++ P +G+Y C A N G+ S +C L ++A
Sbjct: 438 TLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
Score = 42.7 bits (96), Expect = 0.012
Identities = 19/64 (29%), Positives = 37/64 (57%)
Query: 1549 NPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
+P P+I+W K+ I+ + ++ +++ T I+K + G YTCKA++ +G A
Sbjct: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDC 467
Query: 1609 KLQV 1612
+L+V
Sbjct: 468 RLEV 471
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 56.8 bits (131), Expect = 7e-07
Identities = 84/324 (25%), Positives = 125/324 (38%), Gaps = 61/324 (18%)
Query: 1242 ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT-VMDGERIS 1300
E+++ + C A N G V E + + G AP +A T V++G+ +S
Sbjct: 113 ESVAPEDQAPYVCEARNVFGKVQA------EARLIVTGHAPPQIASSAPTVRVLEGQPVS 166
Query: 1301 LNCKIL-GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASN 1359
L C +L GRP P+ W + + + +I S +H+ A E AG Y C A+N
Sbjct: 167 LPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGS----LHLDRALQEHAGRYSCVATN 222
Query: 1360 QFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIR 1419
G + +E VP PRI T T EG
Sbjct: 223 TAGSQHRD----VELVVQVP--------------------PRI-HPTATHHITNEGVPAS 257
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L A G+P P + W ++ T L S +GT ++ P D G V A N
Sbjct: 258 LPCVASGVPAPTITWTKE-TNALTSRGPHYNVSKEGTLLIAQPSA--QDAGAYVCTATNT 314
Query: 1480 LGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEI 1539
+G ++ LSV + KP HM + A VP V + EE
Sbjct: 315 VGFSSQEMRLSVNT--------KPR--IHMNGSRNA-----DVPLQV----TAKAGEE-- 353
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVI 1563
VT + G+P P + W KD++ +
Sbjct: 354 VTLDCEAKGSPPPLVTWTKDSRPV 377
Score = 48.4 bits (110), Expect = 2e-04
Identities = 87/369 (23%), Positives = 128/369 (34%), Gaps = 72/369 (19%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G TCRA N G S E Q + G AP + + TV G L C+ GRP
Sbjct: 24 GTYTCRAVNELGDASA------EIQLAV-GHAPQLTELPRDVTVELGRSALLACRATGRP 76
Query: 1310 WPKIDWFHNE-----KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
P + W + + R + SG+ + + PE Y C A N FGK
Sbjct: 77 PPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGV--LFFESVAPEDQAPYVCEARNVFGKV 134
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKA 1424
E L + + P+I + PT V EG+ + L
Sbjct: 135 QAEARLIVTGHA----------------------PPQIASSAPT-VRVLEGQPVSLPCIV 171
Query: 1425 I-GIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVT 1483
+ G P P+ WL+ G L + + I DG+ L + Q+ G A N T
Sbjct: 172 LAGRPLPERHWLKDGRPLPPGSRHSIRA--DGS--LHLDRALQEHAGRYSCVATN----T 223
Query: 1484 ATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFE 1543
A VE +V P H+ + VP +
Sbjct: 224 AGSQHRDVELVVQVPPRIHPTATHHI--------TNEGVP----------------ASLP 259
Query: 1544 AIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGL 1603
+ SG P P I W K+ + + +KE T I + + G Y C A + +G
Sbjct: 260 CVASGVPAPTITWTKETNALTSRGPHYNVSKEG--TLLIAQPSAQDAGAYVCTATNTVGF 317
Query: 1604 AVTKAKLQV 1612
+ + +L V
Sbjct: 318 SSQEMRLSV 326
Score = 45.2 bits (102), Expect = 0.002
Identities = 75/305 (24%), Positives = 113/305 (37%), Gaps = 34/305 (11%)
Query: 1221 KDSTELTPRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG 1279
KD L P ++A L + ++ G +C A N AGS +V+ I
Sbjct: 184 KDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIH- 242
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
P + N +G SL C G P P I W + T+R + K G
Sbjct: 243 --PTATHHITN----EGVPASLPCVASGVPAPTITWTKETNAL-TSRGPHYNVSKEGT-- 293
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ I + + AG Y CTA+N G S E L++ P + ++ + +DV
Sbjct: 294 LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNT---KPRIH----MNGSRNADV---- 342
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P VT G+ + L+ +A G P P V W + + T + L G+ L
Sbjct: 343 -------PLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITN-RYGLLPSGS--L 392
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT 1519
+ +V D+G A N G + L V+ Q P V H + L
Sbjct: 393 RLAQVQVGDSGHYECTASNPAGSASHRYVLGVQGRTSWQPQSLP--VPHHPACLSGLSVP 450
Query: 1520 QSVPT 1524
PT
Sbjct: 451 LLQPT 455
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated antigen
MG50 protein.
Length = 1496
Score = 56.8 bits (131), Expect = 7e-07
Identities = 78/344 (22%), Positives = 124/344 (36%), Gaps = 60/344 (17%)
Query: 1272 EEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITIS 1331
EE C + P + + ++ V G + C+ G P P+I W N + D ++
Sbjct: 256 EELNC---ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLN 312
Query: 1332 RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK 1391
G I + + GIY+C A N G+ T+ + Y S + + +
Sbjct: 313 LLDDGTLMIQNTQETDQ--GIYQCMAKNVAGEVKTQEV----TLRYFGSPARPTFVIQPQ 366
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE 1451
++V G+ + LE A G P P++ W R G + ++
Sbjct: 367 NTEV-----------------LVGESVTLECSATGHPPPRISWTR-GDRTPLPVDPRVNI 408
Query: 1452 LDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEE 1511
G L + V Q D+GE A N+ ++S+ T
Sbjct: 409 TPSGG--LYIQNVVQGDSGEYACSATNN-----------IDSVHAT-------------- 441
Query: 1512 LQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFII 1571
A Q++P F V E + V F+ GNP P I W K + D R ++
Sbjct: 442 ---AFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLV 498
Query: 1572 ENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQR 1615
+ T I +G Y C+AV+ IG A L V R
Sbjct: 499 LSS---GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR 539
Score = 54.4 bits (125), Expect = 4e-06
Identities = 62/275 (22%), Positives = 113/275 (41%), Gaps = 38/275 (13%)
Query: 1221 KDSTELTPRIIQPLKALN---VLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCI 1277
+++ EL+ + L L+ ++ +N + G+ C A+N AG V T +
Sbjct: 298 RNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQ--EVTLRYFGS 355
Query: 1278 DGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
V+ P +NT V+ GE ++L C G P P+I W ++ D ++ SG
Sbjct: 356 PARPTFVIQP-QNTEVLVGESVTLECSATGHPPPRISWTRGDR-TPLPVDPRVNITPSG- 412
Query: 1338 CEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEE 1397
++I+ +G Y C+A+N + ++A ++ V+ + +T D
Sbjct: 413 -GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVD--- 468
Query: 1398 FAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTS 1457
+ EAK G P P + W + G++L + + L GT
Sbjct: 469 --------------------FQCEAK--GNPPPVIAWTKGGSQLSVDRRHLV--LSSGT- 503
Query: 1458 ILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVE 1492
L + V D G+ +A N +G +A L+V+
Sbjct: 504 -LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 537
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 13/133 (9%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C+A N GS +V T P+ + +TTV G + L C G P
Sbjct: 515 GQYECQAVNIIGS-----QKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEP 569
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W N+ ++ G + I + P AG Y+C A N G S +
Sbjct: 570 EPAITW--NKDGVQVTESGKFHISPEGF--LTINDVGPADAGRYECVARNTIGSASVSMV 625
Query: 1370 LNIEAYEYVPSVS 1382
L++ VP VS
Sbjct: 626 LSVN----VPDVS 634
Score = 41.9 bits (94), Expect = 0.022
Identities = 60/266 (22%), Positives = 101/266 (37%), Gaps = 43/266 (16%)
Query: 1228 PRI-IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLA 1286
PR+ I P L + +N+ + G C A N SV + IV+ P
Sbjct: 404 PRVNITPSGGLYI--QNVVQGDSGEYACSATNNIDSVHATAFIIVQA-------LPQFTV 454
Query: 1287 PLENTTVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITISRQKSGLCEIHIKEA 1345
++ V++G+ + C+ G P P I W +L R + +S SG + I
Sbjct: 455 TPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLS---SGT--LRISGV 509
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
G Y+C A N G L ++ P V+ + +
Sbjct: 510 ALHDQGQYECQAVNIIGSQKVVAHLTVQ-----PRVTP------------------VFAS 546
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
+P+ T G ++L + G P+P + W + G ++ +S ++ I LT+ +V
Sbjct: 547 IPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISP----EGFLTINDVG 602
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSV 1491
D G A N +G + LSV
Sbjct: 603 PADAGRYECVARNTIGSASVSMVLSV 628
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 353 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 412
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 413 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 443
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 353 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 412
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 413 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 456
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 346 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 401
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 402 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 446
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 56.4 bits (130), Expect = 9e-07
Identities = 92/399 (23%), Positives = 156/399 (39%), Gaps = 64/399 (16%)
Query: 1217 HIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTC 1276
+++ D +L P L NV+ +K G C A +V + G+ I
Sbjct: 94 NLVSDDRRQLLPD--GSLFISNVVHSKHNKPDEGYYQCVA-----TVESLGTIISRTAKL 146
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I P + E ++V G LNC++ P + W N + + D + + SG
Sbjct: 147 IVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPL--LLDDRVIKLPSG 204
Query: 1337 LCEIHIKEAFPEMAGIYKCTA-SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
+ + I A G+Y+C S K S E L + + + +V+SD
Sbjct: 205 M--LVISNATEGDGGLYRCVVESGGPPKYSDEVELKV--------LPDPEVISD------ 248
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
+ P+ + G+ + L A G+P P ++W++ L + ++ L G
Sbjct: 249 -----LVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG 303
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + +V +DD G IA E+I E QA
Sbjct: 304 S--LEISDVTEDDA-----------GTYFCIADNGNETI----------------EAQAE 334
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L Q+ P F+K+ HE + FE +G PTP + W K+ ++ + F I +
Sbjct: 335 L-TVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEH 393
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
N + K+ EG Y C A +D+G A A+L + +
Sbjct: 394 NLQVLGLVKSD---EGFYQCIAENDVGNAQAGAQLIILE 429
Score = 35.1 bits (77), Expect = 2.5
Identities = 35/160 (21%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
Query: 1224 TELTPRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAP 1282
TE + R++ L A LE ++++D G C A+N ++ V+ Q P
Sbjct: 291 TESSERLV--LLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ-------P 341
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L N + I C++ G+P P + W N ++ + I ++ + + +
Sbjct: 342 EFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN----LQV 397
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVS 1382
G Y+C A N G L I E+ P+ +
Sbjct: 398 LGLVKSDEGFYQCIAENDVGNAQAGAQLII--LEHAPATT 435
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chicken)
protein.
Length = 1461
Score = 56.4 bits (130), Expect = 9e-07
Identities = 92/399 (23%), Positives = 156/399 (39%), Gaps = 64/399 (16%)
Query: 1217 HIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTC 1276
+++ D +L P L NV+ +K G C A +V + G+ I
Sbjct: 94 NLVSDDRRQLLPD--GSLFISNVVHSKHNKPDEGYYQCVA-----TVESLGTIISRTAKL 146
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I P + E ++V G LNC++ P + W N + + D + + SG
Sbjct: 147 IVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPL--LLDDRVIKLPSG 204
Query: 1337 LCEIHIKEAFPEMAGIYKCTA-SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
+ + I A G+Y+C S K S E L + + + +V+SD
Sbjct: 205 M--LVISNATEGDGGLYRCVVESGGPPKYSDEVELKV--------LPDPEVISD------ 248
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
+ P+ + G+ + L A G+P P ++W++ L + ++ L G
Sbjct: 249 -----LVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG 303
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + +V +DD G IA E+I E QA
Sbjct: 304 S--LEISDVTEDDA-----------GTYFCIADNGNETI----------------EAQAE 334
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L Q+ P F+K+ HE + FE +G PTP + W K+ ++ + F I +
Sbjct: 335 L-TVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEH 393
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
N + K+ EG Y C A +D+G A A+L + +
Sbjct: 394 NLQVLGLVKSD---EGFYQCIAENDVGNAQAGAQLIILE 429
Score = 35.1 bits (77), Expect = 2.5
Identities = 35/160 (21%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
Query: 1224 TELTPRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAP 1282
TE + R++ L A LE ++++D G C A+N ++ V+ Q P
Sbjct: 291 TESSERLV--LLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ-------P 341
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L N + I C++ G+P P + W N ++ + I ++ + + +
Sbjct: 342 EFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN----LQV 397
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVS 1382
G Y+C A N G L I E+ P+ +
Sbjct: 398 LGLVKSDEGFYQCIAENDVGNAQAGAQLII--LEHAPATT 435
>BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein.
Length = 166
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 61 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 120
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 121 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 151
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 33 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 87
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 88 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 147
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 148 ELIVETM 154
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 61 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 120
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 121 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 164
>BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein.
Length = 167
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 62 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 121
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 122 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 152
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 34 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 88
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 89 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 148
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 149 ELIVETM 155
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 62 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 121
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 122 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 165
>BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein.
Length = 227
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 122 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 181
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 182 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 212
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 122 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 181
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 182 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 225
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 115 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 170
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 171 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 215
>BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 41 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
>BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 21 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 75
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 136 ELIVETM 142
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
>BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 21 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 75
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 136 ELIVETM 142
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
>BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 41 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
>BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein.
Length = 236
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 121 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 180
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 181 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 211
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 121 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 180
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 181 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 224
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 114 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 169
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 170 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 214
>BC014671-1|AAH14671.1| 331|Homo sapiens MYOM3 protein protein.
Length = 331
Score = 56.4 bits (130), Expect = 9e-07
Identities = 51/210 (24%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L PL+ +G RI K + K WFH +K +E+ I R + L EI +
Sbjct: 116 LSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRI---RTGTTLDEIWL 172
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRI 1402
P+ + K T GK + ++ + +++E L + + +E+ ++
Sbjct: 173 HILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRL--KTLAIIEKNRAKV 230
Query: 1403 VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTM 1461
V+ LP V T E K + L G P P++ WL+ + Y++E GT + +T+
Sbjct: 231 VRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEV--RGTEVTITI 288
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+V +D+G N G +SV
Sbjct: 289 EKVNSEDSGRYGVFVKNKYGSETGQVTISV 318
Score = 45.6 bits (103), Expect = 0.002
Identities = 22/81 (27%), Positives = 41/81 (50%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
+ E++ + I SG+PTPEI W K+++ + +R+ +E + T TI+K + G Y
Sbjct: 240 IMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRY 299
Query: 1594 TCKAVSDIGLAVTKAKLQVFQ 1614
+ G + + VF+
Sbjct: 300 GVFVKNKYGSETGQVTISVFK 320
>AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member 3
protein.
Length = 1437
Score = 56.4 bits (130), Expect = 9e-07
Identities = 51/210 (24%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L PL+ +G RI K + K WFH +K +E+ I R + L EI +
Sbjct: 1222 LSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRI---RTGTTLDEIWL 1278
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRI 1402
P+ + K T GK + ++ + +++E L + + +E+ ++
Sbjct: 1279 HILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRL--KTLAIIEKNRAKV 1336
Query: 1403 VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTM 1461
V+ LP V T E K + L G P P++ WL+ + Y++E GT + +T+
Sbjct: 1337 VRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEV--RGTEVTITI 1394
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+V +D+G N G +SV
Sbjct: 1395 EKVNSEDSGRYGVFVKNKYGSETGQVTISV 1424
Score = 45.6 bits (103), Expect = 0.002
Identities = 22/81 (27%), Positives = 41/81 (50%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
+ E++ + I SG+PTPEI W K+++ + +R+ +E + T TI+K + G Y
Sbjct: 1346 IMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRY 1405
Query: 1594 TCKAVSDIGLAVTKAKLQVFQ 1614
+ G + + VF+
Sbjct: 1406 GVFVKNKYGSETGQVTISVFK 1426
Score = 37.5 bits (83), Expect = 0.47
Identities = 40/196 (20%), Positives = 72/196 (36%), Gaps = 9/196 (4%)
Query: 1279 GDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIE----TARDITISRQK 1334
G P PL + V + + L C + P P++ W+ N+ I+ A I+
Sbjct: 151 GRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRIT-NN 209
Query: 1335 SGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
GL + I+ E + Y N G+ S+ + + Y + + ++
Sbjct: 210 YGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGP 269
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDD 1454
EF ++K P E + + ++W R G+ L S +I D
Sbjct: 270 SVEFT-SVLK--PVFAREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDR 326
Query: 1455 GTSILTMPEVYQDDTG 1470
S L + Y++D G
Sbjct: 327 QAS-LKVSCTYKEDEG 341
>AL591178-2|CAH72089.1| 330|Homo sapiens myomesin family, member 3
protein.
Length = 330
Score = 56.4 bits (130), Expect = 9e-07
Identities = 51/210 (24%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L PL+ +G RI K + K WFH +K +E+ I R + L EI +
Sbjct: 115 LSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRI---RTGTTLDEIWL 171
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRI 1402
P+ + K T GK + ++ + +++E L + + +E+ ++
Sbjct: 172 HILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRL--KTLAIIEKNRAKV 229
Query: 1403 VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTM 1461
V+ LP V T E K + L G P P++ WL+ + Y++E GT + +T+
Sbjct: 230 VRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEV--RGTEVTITI 287
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+V +D+G N G +SV
Sbjct: 288 EKVNSEDSGRYGVFVKNKYGSETGQVTISV 317
Score = 45.6 bits (103), Expect = 0.002
Identities = 22/81 (27%), Positives = 41/81 (50%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
+ E++ + I SG+PTPEI W K+++ + +R+ +E + T TI+K + G Y
Sbjct: 239 IMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRY 298
Query: 1594 TCKAVSDIGLAVTKAKLQVFQ 1614
+ G + + VF+
Sbjct: 299 GVFVKNKYGSETGQVTISVFK 319
>AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens cDNA
FLJ46367 fis, clone TESTI4051424, weakly similar to
M-protein, striated muscle. ).
Length = 1172
Score = 56.4 bits (130), Expect = 9e-07
Identities = 51/210 (24%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L PL+ +G RI K + K WFH +K +E+ I R + L EI +
Sbjct: 957 LSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRI---RTGTTLDEIWL 1013
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRI 1402
P+ + K T GK + ++ + +++E L + + +E+ ++
Sbjct: 1014 HILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRL--KTLAIIEKNRAKV 1071
Query: 1403 VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTM 1461
V+ LP V T E K + L G P P++ WL+ + Y++E GT + +T+
Sbjct: 1072 VRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEV--RGTEVTITI 1129
Query: 1462 PEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+V +D+G N G +SV
Sbjct: 1130 EKVNSEDSGRYGVFVKNKYGSETGQVTISV 1159
Score = 45.6 bits (103), Expect = 0.002
Identities = 22/81 (27%), Positives = 41/81 (50%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
+ E++ + I SG+PTPEI W K+++ + +R+ +E + T TI+K + G Y
Sbjct: 1081 IMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRY 1140
Query: 1594 TCKAVSDIGLAVTKAKLQVFQ 1614
+ G + + VF+
Sbjct: 1141 GVFVKNKYGSETGQVTISVFK 1161
>AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein
isoform 2 protein.
Length = 154
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 21 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 75
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 136 ELIVETM 142
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
>AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein
isoform 1 protein.
Length = 153
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 41 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
>AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein
protein.
Length = 154
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 21 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 75
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 76 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 136 ELIVETM 142
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 152
>AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein
protein.
Length = 153
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 151
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 41 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 96
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 97 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 141
>AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle
myosin light chain kinase protein.
Length = 300
Score = 56.4 bits (130), Expect = 9e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 195 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 254
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I D + YTCKAV+ +G A A+L V
Sbjct: 255 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 285
Score = 52.4 bits (120), Expect = 2e-05
Identities = 27/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 195 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 254
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 255 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 298
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 1390 EKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQI 1449
E+ V+ + + ++ L V EG R + K G P P+V W + + +S +QI
Sbjct: 188 EEKPHVKPYFSKTIRDLEVV----EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 243
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESI 1494
+ +DG L + +V DD + +A N LG A L VE++
Sbjct: 244 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 288
>AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens cDNA
FLJ27411 fis, clone WMC04903, highly similar to Myosin
light chain kinase, smooth muscle and non-muscle isozymes
).
Length = 572
Score = 56.0 bits (129), Expect = 1e-06
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 11/162 (6%)
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSV-ESIVG--TQEYRKPEWVTHMEELQAAL 1516
T+ ++Q TG V A L A I+ LS +S G T + + + QA L
Sbjct: 398 TLVSIFQK-TGNAV-RAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 455
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVT-----FEAIYSGNPTPEILWYKDNKVIRTDERFII 1571
+A VK + + + + E+V F+ G P PE++W KD++ IR F I
Sbjct: 456 EAVAEEKPHVKPYLSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWSKDDQSIRESRHFQI 515
Query: 1572 E-NKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ +++ + I D + YTCKAV+ +G A A+L V
Sbjct: 516 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 557
Score = 54.8 bits (126), Expect = 3e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 439 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYLSKTIRDLEVV----EGSAARFDCKIEGY 493
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 494 PDPEVVWSKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 553
Query: 1488 ALSVESI 1494
L VE++
Sbjct: 554 ELIVETM 560
Score = 50.0 bits (114), Expect = 8e-05
Identities = 26/104 (25%), Positives = 46/104 (44%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + + V++G +CKI G P P++ W +++ I +R I + G C +
Sbjct: 467 PYLSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWSKDDQSIRESRHFQIDYDEDGNCSLI 526
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + L +E E EE+
Sbjct: 527 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 570
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 56.0 bits (129), Expect = 1e-06
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 34/213 (15%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLC 1338
D +V AP ENTTV+ G+ + + C P P + W + K I T D+ + G
Sbjct: 243 DVVIVAAP-ENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPIST--DVIVL----GRT 295
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEF 1398
+ I A P +G+Y C A+ ++ + +E VL+
Sbjct: 296 NLLIANAQPWHSGVYVCRANKP------------RTRDFATAAAELRVLA---------- 333
Query: 1399 APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI 1458
AP I +A P ++ T R +A G P+P +RWL G L + +++ G
Sbjct: 334 APAITQA-PEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQ---GGGGS 389
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
L + ++ D G A N G+ A+L+V
Sbjct: 390 LVITQIGLQDAGYYQCVAENSAGMACAAASLAV 422
Score = 42.7 bits (96), Expect = 0.012
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 36/229 (15%)
Query: 1218 IIEKDSTELTPR----IIQPLKALNVLEENISKDLIGVV----TCRAENFAGSVSTSGSS 1269
++E D L P + QPL A N +E++ + +GV+ +C A G V S ++
Sbjct: 79 LLEHDHLHLLPNGSLWLSQPL-APNGSDESVP-EAVGVIEGNYSCLAHGPLG-VLASQTA 135
Query: 1270 IVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDI 1328
+V+ T D L P E+ TV + C I G P P I W ++ L E R I
Sbjct: 136 VVKLATLAD----FSLHP-ESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLI 190
Query: 1329 TISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLS 1388
+ + ++ +A P Y+C A+N + ++ E + SV+ L+
Sbjct: 191 VLPNGVLQILDVQESDAGP-----YRCVATNSARQHFSQ--------EALLSVAHRGSLA 237
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQ 1437
+ DV ++ A P T G+ + +E A P P V W+RQ
Sbjct: 238 STRGQDV------VIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQ 280
Score = 33.9 bits (74), Expect = 5.7
Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 3/78 (3%)
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C+ G P P + W HN + + + + G + I + + AG Y+C A N G
Sbjct: 356 CRASGEPRPALRWLHNGAPLRPNGRVKV---QGGGGSLVITQIGLQDAGYYQCVAENSAG 412
Query: 1363 KCSTECILNIEAYEYVPS 1380
L + E +PS
Sbjct: 413 MACAAASLAVVVREGLPS 430
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 55.6 bits (128), Expect = 2e-06
Identities = 92/399 (23%), Positives = 156/399 (39%), Gaps = 64/399 (16%)
Query: 1217 HIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTC 1276
+++ D +L P L NV+ +K G C A +V + G+ I
Sbjct: 94 NLVSDDRRQLLPD--GSLFISNVVHSKHNKPDEGYYQCVA-----TVESLGTIISRTAKL 146
Query: 1277 IDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSG 1336
I P + E ++V G LNC++ P + W N + + D + + SG
Sbjct: 147 IVAGLPRFTSQPEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPL--LLDDRVIKLPSG 204
Query: 1337 LCEIHIKEAFPEMAGIYKCTA-SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDV 1395
+ + I A G+Y+C S K S E L + + + +V+SD
Sbjct: 205 M--LVISNATEGDGGLYRCVVESGGPPKYSDEVELKV--------LPDPEVISD------ 248
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDG 1455
+ P+ + G+ + L A G+P P ++W++ L + ++ L G
Sbjct: 249 -----LVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG 303
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
+ L + +V +DD G IA E+I E QA
Sbjct: 304 S--LEISDVTEDDA-----------GTYFCIADNGNETI----------------EAQAE 334
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
L Q+ P F+K+ HE + FE +G PTP + W K+ ++ + F I +
Sbjct: 335 L-TVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEH 393
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
N + K+ EG Y C A +D+G A A+L + +
Sbjct: 394 NLQVLGLVKSD---EGFYQCIAENDVGNAQAGAQLIILE 429
Score = 35.1 bits (77), Expect = 2.5
Identities = 35/160 (21%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
Query: 1224 TELTPRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAP 1282
TE + R++ L A LE ++++D G C A+N ++ V+ Q P
Sbjct: 291 TESSERLV--LLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ-------P 341
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L N + I C++ G+P P + W N ++ + I ++ + + +
Sbjct: 342 EFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN----LQV 397
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVS 1382
G Y+C A N G L I E+ P+ +
Sbjct: 398 LGLVKSDEGFYQCIAENDVGNAQAGAQLII--LEHAPATT 435
>EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform A
protein.
Length = 1896
Score = 55.6 bits (128), Expect = 2e-06
Identities = 64/267 (23%), Positives = 96/267 (35%), Gaps = 33/267 (12%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGD----------------APLVLAPLENTTV 1293
GV CRA N AG + + V E D + AP+ L + V
Sbjct: 80 GVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWV 139
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE--------IHIKEA 1345
+ G + L C+ G P P + W + ++ D + + G E + I A
Sbjct: 140 LRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAA 199
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
+G+Y C A N G +L + P DE + V E P +K
Sbjct: 200 RLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP-----DEAPAPVVE--P--LKC 250
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
P EGK + +G P+P++ W +G LL + DG +L +
Sbjct: 251 APKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQ 310
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVE 1492
D G V A N G T + L V+
Sbjct: 311 AKDRGLYVCAARNSAGQTLSAVQLHVK 337
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/348 (21%), Positives = 130/348 (37%), Gaps = 34/348 (9%)
Query: 1279 GDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ--KSG 1336
G P L V+ G L C +LG P P + W + + + ++ + G
Sbjct: 9 GSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK---TS 1393
L + A P AG+Y C A N G+ + + P S+ ++ E+ +
Sbjct: 69 LL---LTAALPTDAGVYVCRARNAAGEAYAAAAVTV----LEPPASDPELQPAERPLPSP 121
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG---TELLQSTEYQIE 1450
E AP + P G + L +A G+P+P + W + G E+ S+ + ++
Sbjct: 122 GSGEGAPVFLTG-PRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQ 180
Query: 1451 --ELDDG---TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
+DG + L + D+G V A N G A L V ++ PE
Sbjct: 181 PGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--------HQPPE- 231
Query: 1506 VTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRT 1565
+ +A + + K V+E + F G P PEI W+ + + +
Sbjct: 232 SPPADPDEAPAPVVEPLKCAPKTF---WVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP 288
Query: 1566 D-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D R + +++ + G Y C A + G ++ +L V
Sbjct: 289 DRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 336
Score = 35.1 bits (77), Expect = 2.5
Identities = 38/173 (21%), Positives = 57/173 (32%), Gaps = 6/173 (3%)
Query: 1391 KTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
K S ++ +P P V G L+ +G P P V W + G +L S
Sbjct: 2 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSF- 60
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME 1510
D L + D G V A N G AA++V + +P E
Sbjct: 61 PADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQP-----AE 115
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI 1563
+ + + P F+ + V V G P P + W KD +
Sbjct: 116 RPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMAL 168
Score = 34.3 bits (75), Expect = 4.3
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER--FIIENKENRT 1578
S P F++ P RV + + G P P ++W K + + ER F + E+
Sbjct: 10 SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
T T G Y C+A + G A A + V +
Sbjct: 70 LLTAALPTD--AGVYVCRARNAAGEAYAAAAVTVLE 103
Score = 33.5 bits (73), Expect = 7.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 1431 QVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATI 1486
QVRW + G E+ S Q+ + T LT+P +D GE V E H +T +
Sbjct: 1111 QVRWYKDGLEVEASDALQLGA-EGPTRTLTLPHAQPEDAGEYVCET-RHEAITFNV 1164
>EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform C
protein.
Length = 1544
Score = 55.6 bits (128), Expect = 2e-06
Identities = 64/267 (23%), Positives = 96/267 (35%), Gaps = 33/267 (12%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGD----------------APLVLAPLENTTV 1293
GV CRA N AG + + V E D + AP+ L + V
Sbjct: 80 GVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWV 139
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE--------IHIKEA 1345
+ G + L C+ G P P + W + ++ D + + G E + I A
Sbjct: 140 LRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAA 199
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
+G+Y C A N G +L + P DE + V E P +K
Sbjct: 200 RLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP-----DEAPAPVVE--P--LKC 250
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
P EGK + +G P+P++ W +G LL + DG +L +
Sbjct: 251 APKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQ 310
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVE 1492
D G V A N G T + L V+
Sbjct: 311 AKDRGLYVCAARNSAGQTLSAVQLHVK 337
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/348 (21%), Positives = 130/348 (37%), Gaps = 34/348 (9%)
Query: 1279 GDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ--KSG 1336
G P L V+ G L C +LG P P + W + + + ++ + G
Sbjct: 9 GSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK---TS 1393
L + A P AG+Y C A N G+ + + P S+ ++ E+ +
Sbjct: 69 LL---LTAALPTDAGVYVCRARNAAGEAYAAAAVTV----LEPPASDPELQPAERPLPSP 121
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG---TELLQSTEYQIE 1450
E AP + P G + L +A G+P+P + W + G E+ S+ + ++
Sbjct: 122 GSGEGAPVFLTG-PRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQ 180
Query: 1451 --ELDDG---TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
+DG + L + D+G V A N G A L V ++ PE
Sbjct: 181 PGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--------HQPPE- 231
Query: 1506 VTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRT 1565
+ +A + + K V+E + F G P PEI W+ + + +
Sbjct: 232 SPPADPDEAPAPVVEPLKCAPKTF---WVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP 288
Query: 1566 D-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D R + +++ + G Y C A + G ++ +L V
Sbjct: 289 DRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 336
Score = 35.1 bits (77), Expect = 2.5
Identities = 38/173 (21%), Positives = 57/173 (32%), Gaps = 6/173 (3%)
Query: 1391 KTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
K S ++ +P P V G L+ +G P P V W + G +L S
Sbjct: 2 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSF- 60
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME 1510
D L + D G V A N G AA++V + +P E
Sbjct: 61 PADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQP-----AE 115
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI 1563
+ + + P F+ + V V G P P + W KD +
Sbjct: 116 RPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMAL 168
Score = 34.3 bits (75), Expect = 4.3
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDER--FIIENKENRT 1578
S P F++ P RV + + G P P ++W K + + ER F + E+
Sbjct: 10 SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGL 69
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
T T G Y C+A + G A A + V +
Sbjct: 70 LLTAALPTD--AGVYVCRARNAAGEAYAAAAVTVLE 103
Score = 33.5 bits (73), Expect = 7.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 1431 QVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATI 1486
QVRW + G E+ S Q+ + T LT+P +D GE V E H +T +
Sbjct: 1112 QVRWYKDGLEVEASDALQLGA-EGPTRTLTLPHAQPEDAGEYVCET-RHEAITFNV 1165
>BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein.
Length = 1044
Score = 55.6 bits (128), Expect = 2e-06
Identities = 64/267 (23%), Positives = 96/267 (35%), Gaps = 33/267 (12%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGD----------------APLVLAPLENTTV 1293
GV CRA N AG + + V E D + AP+ L + V
Sbjct: 99 GVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWV 158
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE--------IHIKEA 1345
+ G + L C+ G P P + W + ++ D + + G E + I A
Sbjct: 159 LRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAA 218
Query: 1346 FPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKA 1405
+G+Y C A N G +L + P DE + V E P +K
Sbjct: 219 RLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADP-----DEAPAPVVE--P--LKC 269
Query: 1406 LPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVY 1465
P EGK + +G P+P++ W +G LL + DG +L +
Sbjct: 270 APKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQ 329
Query: 1466 QDDTGEIVFEAYNHLGVTATIAALSVE 1492
D G V A N G T + L V+
Sbjct: 330 AKDRGLYVCAARNSAGQTLSAVQLHVK 356
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/348 (21%), Positives = 130/348 (37%), Gaps = 34/348 (9%)
Query: 1279 GDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ--KSG 1336
G P L V+ G L C +LG P P + W + + + ++ + G
Sbjct: 28 GSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 87
Query: 1337 LCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEK---TS 1393
L + A P AG+Y C A N G+ + + P S+ ++ E+ +
Sbjct: 88 LL---LTAALPTDAGVYVCRARNAAGEAYAAAAVTV----LEPPASDPELQPAERPLPSP 140
Query: 1394 DVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG---TELLQSTEYQIE 1450
E AP + P G + L +A G+P+P + W + G E+ S+ + ++
Sbjct: 141 GSGEGAPVFLTG-PRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQ 199
Query: 1451 --ELDDG---TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
+DG + L + D+G V A N G A L V ++ PE
Sbjct: 200 PGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV--------HQPPE- 250
Query: 1506 VTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRT 1565
+ +A + + K V+E + F G P PEI W+ + + +
Sbjct: 251 SPPADPDEAPAPVVEPLKCAPKTF---WVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP 307
Query: 1566 D-ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
D R + +++ + G Y C A + G ++ +L V
Sbjct: 308 DRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 355
Score = 36.7 bits (81), Expect = 0.81
Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 8/118 (6%)
Query: 1503 PEWVTHMEELQAALKATQ----SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYK 1558
P V AA+KA+ S P F++ P RV + + G P P ++W K
Sbjct: 7 PPTVRRCRRSAAAMKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEK 66
Query: 1559 DNKVIRTDER--FIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
+ + ER F + E+ T T G Y C+A + G A A + V +
Sbjct: 67 GGQQLAASERLSFPADGAEHGLLLTAALPTD--AGVYVCRARNAAGEAYAAAAVTVLE 122
Score = 35.1 bits (77), Expect = 2.5
Identities = 38/173 (21%), Positives = 57/173 (32%), Gaps = 6/173 (3%)
Query: 1391 KTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIE 1450
K S ++ +P P V G L+ +G P P V W + G +L S
Sbjct: 21 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSF- 79
Query: 1451 ELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME 1510
D L + D G V A N G AA++V + +P E
Sbjct: 80 PADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQP-----AE 134
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI 1563
+ + + P F+ + V V G P P + W KD +
Sbjct: 135 RPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMAL 187
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 55.2 bits (127), Expect = 2e-06
Identities = 74/322 (22%), Positives = 139/322 (43%), Gaps = 36/322 (11%)
Query: 191 NVDTTSSKLETKSWRKPRLEESLEEVGPTKGVNEPEVC-----HWRKPKTSEILKDKNEE 245
++DT + L+ K ++ L++V K ++ E C H ++ K + ++ E
Sbjct: 668 HLDTAQNALQDKQQELNKITTQLDQV-TAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTE 726
Query: 246 EIRVQEMKKQSTKALEVKDESKQKIPWTQEA------IKLRPTKVEKS-PIEKEKIEDVA 298
E+ Q +KK +LEVK +Q + Q+ ++LR T++ K +EKE +
Sbjct: 727 ELEGQ-IKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTR 785
Query: 299 LKPVRKDSLMDEKSSEISELQNERQITEKK-ESL-QETQLQPTEKNKLLENIVSEESKES 356
L +K ++ ++++ + E+QI ++ E+L QET++Q E N ++ V+E K
Sbjct: 786 LDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVK 845
Query: 357 TGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLK---PVLTTEKESKETEDRINTKD 413
K E++ + L V + K +L EK KE + ++
Sbjct: 846 MEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ--- 902
Query: 414 TRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDD 473
Q L+ K K +EKEK LK ++ + E++ ++ L
Sbjct: 903 --------VQMENTLKEQKELKKSLEKEKEASHQLKLE-----LNSMQEQLIQAQNTLKQ 949
Query: 474 IEKEEHK-PDKVSENNAPEERK 494
EKEE + ++E E+K
Sbjct: 950 NEKEEQQLQGNINELKQSSEQK 971
Score = 39.5 bits (88), Expect = 0.12
Identities = 74/362 (20%), Positives = 153/362 (42%), Gaps = 46/362 (12%)
Query: 144 EEHVKVQEVVETKLWR------KPKTISE--KKDLLQVSTHEDTNILKVENLESVNVDTT 195
+E ++E E K+ R K T+ + K +LLQ ED +LK E V V T
Sbjct: 180 DEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKE---LVQVQTL 236
Query: 196 SSKLETKSWRKP-RLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKK 254
+ + R+ +L++ +++ +E + R SE+ K E + VQE++K
Sbjct: 237 MDNMTLERERESEKLKDECKKLQSQYASSEATISQLR----SELAKGPQEVAVYVQELQK 292
Query: 255 QSTKALEVKDESKQKIPWTQEAIKLRP--TKVEKSPIEKEKIEDVALKPVRKDSLMDEKS 312
+ E+ +++ T+ +K TK+E EK E V+ K ++ + + +K
Sbjct: 293 LKSSVNELTQKNQ---TLTENLLKKEQDYTKLE----EKHNEESVSKKNIQ--ATLHQKD 343
Query: 313 SEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVA 372
+ +LQ+ +++ + SL ++ +EK + + + E S+ T + + E Q +
Sbjct: 344 LDCQQLQS--RLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQ 401
Query: 373 LKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTK 432
+ K +L TE++ E R+ K+ R+ S
Sbjct: 402 REEKEQHGLQLQSEINQLHSK-LLETERQLGEAHGRL--KEQRQLS-------------- 444
Query: 433 MEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEE 492
EK ++++ D+ LK +R + + E L+ LD +++ + + ++ +
Sbjct: 445 SEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKL 504
Query: 493 RK 494
R+
Sbjct: 505 RE 506
Score = 37.1 bits (82), Expect = 0.61
Identities = 43/197 (21%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 314 EISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVAL 373
E + E+Q+ E+ ++LQ+ Q + + K K L N S+ ++ K RQ +EIT+ L
Sbjct: 1088 EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL 1147
Query: 374 KTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKM 433
K+ + K +L +K E + + ++ Q+ +K K
Sbjct: 1148 KSHK--LESIKEITNLKDAKQLLIQQK--LELQGKADSLKAAVEQEKRNQQILK-DQVKK 1202
Query: 434 EKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEER 493
E+ ++KE E ++ L EI E+ +K ++ K + ++EN ++
Sbjct: 1203 EEEELKKEFIE-------KEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255
Query: 494 KWPTGKRQPKEETPQEE 510
+W + +R+ E Q +
Sbjct: 1256 EWQSSQRRVSELEKQTD 1272
>BC132902-1|AAI32903.1| 354|Homo sapiens myosin binding protein
H-like protein.
Length = 354
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP PL N T + G L C + P PKI W N+ I+ + G+C
Sbjct: 259 EAPKFTQPLANCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR-ALTHLGICS 317
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ I++ P GIY C A N G+ S +C ++++
Sbjct: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
Score = 34.3 bits (75), Expect = 4.3
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 1549 NPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
+P P+I+W K+ I+ + ++ + I+K G YTCKAV+ +G A
Sbjct: 287 SPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
Query: 1609 KLQV 1612
++ V
Sbjct: 347 RVDV 350
>BC132900-1|AAI32901.1| 354|Homo sapiens myosin binding protein
H-like protein.
Length = 354
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP PL N T + G L C + P PKI W N+ I+ + G+C
Sbjct: 259 EAPKFTQPLANCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR-ALTHLGICS 317
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ I++ P GIY C A N G+ S +C ++++
Sbjct: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
Score = 34.3 bits (75), Expect = 4.3
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 1549 NPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
+P P+I+W K+ I+ + ++ + I+K G YTCKAV+ +G A
Sbjct: 287 SPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
Query: 1609 KLQV 1612
++ V
Sbjct: 347 RVDV 350
>AY211921-1|AAO65174.1| 294|Homo sapiens sarcoma antigen NY-SAR-77
protein.
Length = 294
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 4/129 (3%)
Query: 1248 LIGVVTCRAENFAGSVSTSGSSIVEEQTCID-GDAPLVLAPLENTTVMDGERISLNCKIL 1306
LI + R E V SG + ++ G AP L++ + +G ++ C++
Sbjct: 97 LISEIEYRLER--SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVA 154
Query: 1307 GRPWPKIDWFHNEKLIETARD-ITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
G P PKI WF + K I D TI R G C +H + + G Y A+N G+ S
Sbjct: 155 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 214
Query: 1366 TECILNIEA 1374
L ++A
Sbjct: 215 CTGRLMVQA 223
Score = 44.4 bits (100), Expect = 0.004
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P F ++ ++ E VTF +GNP P+I W+KD K I ++ TC++
Sbjct: 130 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 189
Query: 1583 --KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+T D +G YT A + G +L V
Sbjct: 190 HTTASTLDDDGNYTIMAANPQGRISCTGRLMV 221
Score = 39.9 bits (89), Expect = 0.087
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELL-QSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
EG + + G PKP++ W + G ++ +S Y I+ DGT L DD G
Sbjct: 143 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 202
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKP 1503
A N G + L V+++ Q R P
Sbjct: 203 TIMAANPQGRISCTGRLMVQAV--NQRGRSP 231
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 54.8 bits (126), Expect = 3e-06
Identities = 74/322 (22%), Positives = 139/322 (43%), Gaps = 36/322 (11%)
Query: 191 NVDTTSSKLETKSWRKPRLEESLEEVGPTKGVNEPEVC-----HWRKPKTSEILKDKNEE 245
++DT + L+ K ++ L++V K ++ E C H ++ K + ++ E
Sbjct: 668 HLDTAQNALQDKHQELNKITTQLDQV-TAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTE 726
Query: 246 EIRVQEMKKQSTKALEVKDESKQKIPWTQEA------IKLRPTKVEKS-PIEKEKIEDVA 298
E+ Q +KK +LEVK +Q + Q+ ++LR T++ K +EKE +
Sbjct: 727 ELEGQ-IKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTR 785
Query: 299 LKPVRKDSLMDEKSSEISELQNERQITEKK-ESL-QETQLQPTEKNKLLENIVSEESKES 356
L +K ++ ++++ + E+QI ++ E+L QET++Q E N ++ V+E K
Sbjct: 786 LDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVK 845
Query: 357 TGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLK---PVLTTEKESKETEDRINTKD 413
K E++ + L V + K +L EK KE + ++
Sbjct: 846 MEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ--- 902
Query: 414 TRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDD 473
Q L+ K K +EKEK LK ++ + E++ ++ L
Sbjct: 903 --------VQMENTLKEQKELKKSLEKEKEASHQLKLE-----LNSMQEQLIQAQNTLKQ 949
Query: 474 IEKEEHK-PDKVSENNAPEERK 494
EKEE + ++E E+K
Sbjct: 950 NEKEEQQLQGNINELKQSSEQK 971
Score = 38.3 bits (85), Expect = 0.27
Identities = 74/362 (20%), Positives = 152/362 (41%), Gaps = 46/362 (12%)
Query: 144 EEHVKVQEVVETKLWR------KPKTISE--KKDLLQVSTHEDTNILKVENLESVNVDTT 195
+E ++E E K+ R K T+ + K +LLQ ED +LK E V V T
Sbjct: 180 DEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKE---LVQVQTL 236
Query: 196 SSKLETKSWRKP-RLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKK 254
+ + R+ +L++ ++ +E + R SE+ K E + VQE++K
Sbjct: 237 MDNMTLERERESEKLKDESKKFESQYASSEATISQLR----SELSKGPQEVRVYVQELQK 292
Query: 255 QSTKALEVKDESKQKIPWTQEAIKLRP--TKVEKSPIEKEKIEDVALKPVRKDSLMDEKS 312
+ E+ +++ T+ +K TK+E EK E V+ K ++ + + +K
Sbjct: 293 LKSSVNELTQKNQ---TLTENLLKKEQDYTKLE----EKHNEESVSKKNIQ--ATLHQKD 343
Query: 313 SEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVA 372
+ +LQ+ +++ + SL ++ +EK + + + E S+ T + + E Q +
Sbjct: 344 LDCQQLQS--RLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQ 401
Query: 373 LKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTK 432
+ K +L TE++ E R+ K+ R+ S
Sbjct: 402 REEKEQHGLQLQSEINQLHSK-LLETERQLGEAHGRL--KEQRQLS-------------- 444
Query: 433 MEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEE 492
EK ++++ D+ LK +R + + E L+ LD +++ + + ++ +
Sbjct: 445 SEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKL 504
Query: 493 RK 494
R+
Sbjct: 505 RE 506
Score = 37.1 bits (82), Expect = 0.61
Identities = 43/197 (21%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 314 EISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVAL 373
E + E+Q+ E+ ++LQ+ Q + + K K L N S+ ++ K RQ +EIT+ L
Sbjct: 1088 EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL 1147
Query: 374 KTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKM 433
K+ + K +L +K E + + ++ Q+ +K K
Sbjct: 1148 KSHK--LESIKEITNLKDAKQLLIQQK--LELQGKADSLKAAVEQEKRNQQILK-DQVKK 1202
Query: 434 EKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEER 493
E+ ++KE E ++ L EI E+ +K ++ K + ++EN ++
Sbjct: 1203 EEEELKKEFIE-------KEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255
Query: 494 KWPTGKRQPKEETPQEE 510
+W + +R+ E Q +
Sbjct: 1256 EWQSSQRRVSELEKQTD 1272
>BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein
protein.
Length = 370
Score = 54.8 bits (126), Expect = 3e-06
Identities = 56/253 (22%), Positives = 101/253 (39%), Gaps = 19/253 (7%)
Query: 1249 IGVVTCRAENFAG------SVSTSGSSIVE--EQTCIDGDAPLVLAPLENTT-VMDGERI 1299
+G TC A N G +V+ +G +V+ T I+ + P V + +T + G +
Sbjct: 6 VGFYTCNATNALGYDSVSIAVTLAGKPLVKTSRMTVINTEKPAVTVDIGSTIKTVQGVNV 65
Query: 1300 SLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASN 1359
++NC++ G P ++ WF N+ + + + + L ++ + G+Y C A+N
Sbjct: 66 TINCQVAGVPEAEVTWFRNKSKLGSPHHL----HEGSLLLTNVSSS---DQGLYSCRAAN 118
Query: 1360 QFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIR 1419
G+ + L I VP+ E+ + + + L T + G
Sbjct: 119 LHGELTESTQLLILDPPQVPTQLED--IRALLAATGPNLPSVLTSPLGTQLVLGPGNSAL 176
Query: 1420 LEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNH 1479
L G P P + W G ++ +T L G IL + + GE A N
Sbjct: 177 LGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAG-QILQVANLSGGSQGEFSCLAQNE 235
Query: 1480 LGVTATIAALSVE 1492
GV A+L ++
Sbjct: 236 AGVLMQKASLVIQ 248
Score = 47.2 bits (107), Expect = 6e-04
Identities = 55/266 (20%), Positives = 106/266 (39%), Gaps = 29/266 (10%)
Query: 1351 GIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVV 1410
G Y C A+N G S + + V + S V++ EK P + + + +
Sbjct: 7 GFYTCNATNALGYDSVSIAVTLAGKPLVKT-SRMTVINTEK--------PAVTVDIGSTI 57
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
T +G + + + G+P+ +V W R ++L L +G+ +LT V D G
Sbjct: 58 KTVQGVNVTINCQVAGVPEAEVTWFRNKSKLGSP-----HHLHEGSLLLT--NVSSSDQG 110
Query: 1471 EIVFEAYN-HLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKAT-QSVPTFVKE 1528
A N H +T + L ++ P+ T +E+++A L AT ++P+ +
Sbjct: 111 LYSCRAANLHGELTESTQLLILD---------PPQVPTQLEDIRALLAATGPNLPSVLTS 161
Query: 1529 IIPER--VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
+ + + G+P P I W+ + I T + +
Sbjct: 162 PLGTQLVLGPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQILQVANLS 221
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+G ++C A ++ G+ + KA L +
Sbjct: 222 GGSQGEFSCLAQNEAGVLMQKASLVI 247
Score = 43.2 bits (97), Expect = 0.009
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 17/154 (11%)
Query: 1238 NVLEENISKDLIGVVTCRAENFAGSVSTSGSSIV----EEQTCIDG----------DAPL 1283
++L N+S G+ +CRA N G ++ S ++ + T ++ + P
Sbjct: 98 SLLLTNVSSSDQGLYSCRAANLHGELTESTQLLILDPPQVPTQLEDIRALLAATGPNLPS 157
Query: 1284 VL-APLENTTVMD-GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
VL +PL V+ G L C I G P P I WFH + I TA +T +G +
Sbjct: 158 VLTSPLGTQLVLGPGNSALLGCPIKGHPVPNITWFHGGQPIVTATGLTHHILAAGQI-LQ 216
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAY 1375
+ G + C A N+ G + L I+ Y
Sbjct: 217 VANLSGGSQGEFSCLAQNEAGVLMQKASLVIQDY 250
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 54.8 bits (126), Expect = 3e-06
Identities = 71/274 (25%), Positives = 113/274 (41%), Gaps = 47/274 (17%)
Query: 1237 LNVLEENISKDLIGVVTCRAEN-FAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD 1295
L +L S D G+ C A N G+V + G+ V+ + P + P N +++
Sbjct: 84 LTILSVEDSDD--GIYCCTANNGVGGAVESCGALQVKMK-------PKITRPPINVKIIE 134
Query: 1296 GERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C +G P P + W + L E +R I+ +SG IH E AG Y+
Sbjct: 135 GLKAVLPCTTMGNPKPSVSWIKGDSPLRENSR---IAVLESGSLRIH--NVQKEDAGQYR 189
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C A N G AY V + +VE FA RI++A P T
Sbjct: 190 CVAKNSLG----------TAYSKVVKL------------EVEVFA-RILRA-PESHNVTF 225
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQ-STEYQIEE--LDDGTSI-LTMPEVYQDDTG 1470
G + L A GIP P + W+ G + S + +++ +D + +T P +Y
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 1471 EIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
E ++ ATI S+ ++ + KP+
Sbjct: 286 NKHGEKFSTAKAAATI---SIAEMLFISSFSKPQ 316
Score = 51.6 bits (118), Expect = 3e-05
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ PLE + E + C + P P+I W N+ LI+ D S +++G +
Sbjct: 27 APVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLF-DTRYSIRENGQL-L 84
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTEC-ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I GIY CTA+N G C L + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV------------------------KMK 120
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + P V EG L +G PKP V W++ + L +++ +I L+ G+ L
Sbjct: 121 PKITRP-PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGS--L 175
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
+ V ++D G+ A N LG TA + +E V + R PE
Sbjct: 176 RIHNVQKEDAGQYRCVAKNSLG-TAYSKVVKLEVEVFARILRAPE 219
Score = 39.5 bits (88), Expect = 0.12
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Query: 1537 EEIVTFEAIYSGNPTPEILWYKDNKVIRT-DERFIIENKENRTTCTIKKATKDLEGTYTC 1595
EE+ TF P PEI W ++ +I+ D R+ I +EN TI +G Y C
Sbjct: 42 EEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSI--RENGQLLTILSVEDSDDGIYCC 99
Query: 1596 KAVSDIGLAV 1605
A + +G AV
Sbjct: 100 TANNGVGGAV 109
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 1548 GNPTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLA-- 1604
GNP P + W K + +R + R ++E+ R I K+ G Y C A + +G A
Sbjct: 146 GNPKPSVSWIKGDSPLRENSRIAVLESGSLR----IHNVQKEDAGQYRCVAKNSLGTAYS 201
Query: 1605 -VTKAKLQVFQR 1615
V K +++VF R
Sbjct: 202 KVVKLEVEVFAR 213
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 54.8 bits (126), Expect = 3e-06
Identities = 71/274 (25%), Positives = 113/274 (41%), Gaps = 47/274 (17%)
Query: 1237 LNVLEENISKDLIGVVTCRAEN-FAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD 1295
L +L S D G+ C A N G+V + G+ V+ + P + P N +++
Sbjct: 84 LTILSVEDSDD--GIYCCTANNGVGGAVESCGALQVKMK-------PKITRPPINVKIIE 134
Query: 1296 GERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C +G P P + W + L E +R I+ +SG IH E AG Y+
Sbjct: 135 GLKAVLPCTTMGNPKPSVSWIKGDSPLRENSR---IAVLESGSLRIH--NVQKEDAGQYR 189
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C A N G AY V + +VE FA RI++A P T
Sbjct: 190 CVAKNSLG----------TAYSKVVKL------------EVEVFA-RILRA-PESHNVTF 225
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQ-STEYQIEE--LDDGTSI-LTMPEVYQDDTG 1470
G + L A GIP P + W+ G + S + +++ +D + +T P +Y
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 1471 EIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
E ++ ATI S+ ++ + KP+
Sbjct: 286 NKHGEKFSTAKAAATI---SIAEMLFISSFSKPQ 316
Score = 51.6 bits (118), Expect = 3e-05
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ PLE + E + C + P P+I W N+ LI+ D S +++G +
Sbjct: 27 APVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLF-DTRYSIRENGQL-L 84
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTEC-ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I GIY CTA+N G C L + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV------------------------KMK 120
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + P V EG L +G PKP V W++ + L +++ +I L+ G+ L
Sbjct: 121 PKITRP-PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGS--L 175
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
+ V ++D G+ A N LG TA + +E V + R PE
Sbjct: 176 RIHNVQKEDAGQYRCVAKNSLG-TAYSKVVKLEVEVFARILRAPE 219
Score = 39.5 bits (88), Expect = 0.12
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Query: 1537 EEIVTFEAIYSGNPTPEILWYKDNKVIRT-DERFIIENKENRTTCTIKKATKDLEGTYTC 1595
EE+ TF P PEI W ++ +I+ D R+ I +EN TI +G Y C
Sbjct: 42 EEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSI--RENGQLLTILSVEDSDDGIYCC 99
Query: 1596 KAVSDIGLAV 1605
A + +G AV
Sbjct: 100 TANNGVGGAV 109
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 1548 GNPTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLA-- 1604
GNP P + W K + +R + R ++E+ R I K+ G Y C A + +G A
Sbjct: 146 GNPKPSVSWIKGDSPLRENSRIAVLESGSLR----IHNVQKEDAGQYRCVAKNSLGTAYS 201
Query: 1605 -VTKAKLQVFQR 1615
V K +++VF R
Sbjct: 202 KVVKLEVEVFAR 213
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 54.8 bits (126), Expect = 3e-06
Identities = 71/274 (25%), Positives = 113/274 (41%), Gaps = 47/274 (17%)
Query: 1237 LNVLEENISKDLIGVVTCRAEN-FAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD 1295
L +L S D G+ C A N G+V + G+ V+ + P + P N +++
Sbjct: 84 LTILSVEDSDD--GIYCCTANNGVGGAVESCGALQVKMK-------PKITRPPINVKIIE 134
Query: 1296 GERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C +G P P + W + L E +R I+ +SG IH E AG Y+
Sbjct: 135 GLKAVLPCTTMGNPKPSVSWIKGDSPLRENSR---IAVLESGSLRIH--NVQKEDAGQYR 189
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C A N G AY V + +VE FA RI++A P T
Sbjct: 190 CVAKNSLG----------TAYSKVVKL------------EVEVFA-RILRA-PESHNVTF 225
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQ-STEYQIEE--LDDGTSI-LTMPEVYQDDTG 1470
G + L A GIP P + W+ G + S + +++ +D + +T P +Y
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 1471 EIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
E ++ ATI S+ ++ + KP+
Sbjct: 286 NKHGEKFSTAKAAATI---SIAEMLFISSFSKPQ 316
Score = 51.6 bits (118), Expect = 3e-05
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ PLE + E + C + P P+I W N+ LI+ D S +++G +
Sbjct: 27 APVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLF-DTRYSIRENGQL-L 84
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTEC-ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I GIY CTA+N G C L + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV------------------------KMK 120
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + P V EG L +G PKP V W++ + L +++ +I L+ G+ L
Sbjct: 121 PKITRP-PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGS--L 175
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
+ V ++D G+ A N LG TA + +E V + R PE
Sbjct: 176 RIHNVQKEDAGQYRCVAKNSLG-TAYSKVVKLEVEVFARILRAPE 219
Score = 39.5 bits (88), Expect = 0.12
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Query: 1537 EEIVTFEAIYSGNPTPEILWYKDNKVIRT-DERFIIENKENRTTCTIKKATKDLEGTYTC 1595
EE+ TF P PEI W ++ +I+ D R+ I +EN TI +G Y C
Sbjct: 42 EEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSI--RENGQLLTILSVEDSDDGIYCC 99
Query: 1596 KAVSDIGLAV 1605
A + +G AV
Sbjct: 100 TANNGVGGAV 109
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 1548 GNPTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLA-- 1604
GNP P + W K + +R + R ++E+ R I K+ G Y C A + +G A
Sbjct: 146 GNPKPSVSWIKGDSPLRENSRIAVLESGSLR----IHNVQKEDAGQYRCVAKNSLGTAYS 201
Query: 1605 -VTKAKLQVFQR 1615
V K +++VF R
Sbjct: 202 KVVKLEVEVFAR 213
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 54.8 bits (126), Expect = 3e-06
Identities = 71/274 (25%), Positives = 113/274 (41%), Gaps = 47/274 (17%)
Query: 1237 LNVLEENISKDLIGVVTCRAEN-FAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD 1295
L +L S D G+ C A N G+V + G+ V+ + P + P N +++
Sbjct: 84 LTILSVEDSDD--GIYCCTANNGVGGAVESCGALQVKMK-------PKITRPPINVKIIE 134
Query: 1296 GERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C +G P P + W + L E +R I+ +SG IH E AG Y+
Sbjct: 135 GLKAVLPCTTMGNPKPSVSWIKGDSPLRENSR---IAVLESGSLRIH--NVQKEDAGQYR 189
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C A N G AY V + +VE FA RI++A P T
Sbjct: 190 CVAKNSLG----------TAYSKVVKL------------EVEVFA-RILRA-PESHNVTF 225
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGTELLQ-STEYQIEE--LDDGTSI-LTMPEVYQDDTG 1470
G + L A GIP P + W+ G + S + +++ +D + +T P +Y
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIAT 285
Query: 1471 EIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
E ++ ATI S+ ++ + KP+
Sbjct: 286 NKHGEKFSTAKAAATI---SIAEMLFISSFSKPQ 316
Score = 51.6 bits (118), Expect = 3e-05
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ PLE + E + C + P P+I W N+ LI+ D S +++G +
Sbjct: 27 APVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLF-DTRYSIRENGQL-L 84
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTEC-ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I GIY CTA+N G C L + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV------------------------KMK 120
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + P V EG L +G PKP V W++ + L +++ +I L+ G+ L
Sbjct: 121 PKITRP-PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGS--L 175
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
+ V ++D G+ A N LG TA + +E V + R PE
Sbjct: 176 RIHNVQKEDAGQYRCVAKNSLG-TAYSKVVKLEVEVFARILRAPE 219
Score = 39.5 bits (88), Expect = 0.12
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Query: 1537 EEIVTFEAIYSGNPTPEILWYKDNKVIRT-DERFIIENKENRTTCTIKKATKDLEGTYTC 1595
EE+ TF P PEI W ++ +I+ D R+ I +EN TI +G Y C
Sbjct: 42 EEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSI--RENGQLLTILSVEDSDDGIYCC 99
Query: 1596 KAVSDIGLAV 1605
A + +G AV
Sbjct: 100 TANNGVGGAV 109
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 1548 GNPTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLA-- 1604
GNP P + W K + +R + R ++E+ R I K+ G Y C A + +G A
Sbjct: 146 GNPKPSVSWIKGDSPLRENSRIAVLESGSLR----IHNVQKEDAGQYRCVAKNSLGTAYS 201
Query: 1605 -VTKAKLQVFQR 1615
V K +++VF R
Sbjct: 202 KVVKLEVEVFAR 213
>AK093280-1|BAC04119.1| 330|Homo sapiens protein ( Homo sapiens cDNA
FLJ35961 fis, clone TESTI2012528, weakly similar to
M-PROTEIN, STRIATED MUSCLE. ).
Length = 330
Score = 54.8 bits (126), Expect = 3e-06
Identities = 49/206 (23%), Positives = 90/206 (43%), Gaps = 9/206 (4%)
Query: 1283 LVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHI 1342
L PL+ +G RI K + K WFH +K +E+ I R + L EI +
Sbjct: 115 LSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRI---RTGTTLDEIWL 171
Query: 1343 KEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRI 1402
P+ + K T GK + ++ + +++E L + + +E+ ++
Sbjct: 172 HILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRL--KTLAIIEKNRAKV 229
Query: 1403 VKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-LTM 1461
V+ LP V T E + + L G P P++ WL+ + Y++E GT + +T+
Sbjct: 230 VRGLPDVATIMEDRTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEV--RGTEVTITI 287
Query: 1462 PEVYQDDTGEI-VFEAYNHLGVTATI 1486
+V +D+G VF ++ T +
Sbjct: 288 EKVNSEDSGRYGVFVKNKYVSETGQV 313
Score = 43.2 bits (97), Expect = 0.009
Identities = 19/60 (31%), Positives = 33/60 (55%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTY 1593
+ E+ + I SG+PTPEI W K+++ + +R+ +E + T TI+K + G Y
Sbjct: 239 IMEDRTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRY 298
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 54.4 bits (125), Expect = 4e-06
Identities = 59/204 (28%), Positives = 85/204 (41%), Gaps = 40/204 (19%)
Query: 1237 LNVLEENISKDLIGVVTCRAEN-FAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD 1295
L +L S D G+ C A N G+V + G+ V+ + P + P N +++
Sbjct: 84 LTILSVEDSDD--GIYCCTANNGVGGAVESCGALQVKMK-------PKITRPPINVKIIE 134
Query: 1296 GERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C +G P P + W + L E +R I+ +SG IH E AG Y+
Sbjct: 135 GLKAVLPCTTMGNPKPSVSWIKGDSPLRENSR---IAVLESGSLRIH--NVQKEDAGQYR 189
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C A N G AY V + +VE FA RI++A P T
Sbjct: 190 CVAKNSLG----------TAYSKVVKL------------EVEVFA-RILRA-PESHNVTF 225
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQG 1438
G + L A GIP P + W+ G
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENG 249
Score = 51.6 bits (118), Expect = 3e-05
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ PLE + E + C + P P+I W N+ LI+ D S +++G +
Sbjct: 27 APVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLF-DTRYSIRENGQL-L 84
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTEC-ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I GIY CTA+N G C L + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV------------------------KMK 120
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + P V EG L +G PKP V W++ + L +++ +I L+ G+ L
Sbjct: 121 PKITRP-PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGS--L 175
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
+ V ++D G+ A N LG TA + +E V + R PE
Sbjct: 176 RIHNVQKEDAGQYRCVAKNSLG-TAYSKVVKLEVEVFARILRAPE 219
Score = 41.9 bits (94), Expect = 0.022
Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 9/121 (7%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ K+ G C A+N S+ T+ S +V+ + ++ A ++ AP E+ V G ++L+
Sbjct: 179 NVQKEDAGQYRCVAKN---SLGTAYSKVVKLE--VEVFARILRAP-ESHNVTFGSFVTLH 232
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P P I W N + + I S K + + + + F G+Y C A+N+ G
Sbjct: 233 CTATGIPVPTITWIENGNAVSSG-SIQES-VKDRVIDSRL-QLFITKPGLYTCIATNKHG 289
Query: 1363 K 1363
+
Sbjct: 290 E 290
Score = 39.5 bits (88), Expect = 0.12
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Query: 1537 EEIVTFEAIYSGNPTPEILWYKDNKVIRT-DERFIIENKENRTTCTIKKATKDLEGTYTC 1595
EE+ TF P PEI W ++ +I+ D R+ I +EN TI +G Y C
Sbjct: 42 EEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSI--RENGQLLTILSVEDSDDGIYCC 99
Query: 1596 KAVSDIGLAV 1605
A + +G AV
Sbjct: 100 TANNGVGGAV 109
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 1548 GNPTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLA-- 1604
GNP P + W K + +R + R ++E+ R I K+ G Y C A + +G A
Sbjct: 146 GNPKPSVSWIKGDSPLRENSRIAVLESGSLR----IHNVQKEDAGQYRCVAKNSLGTAYS 201
Query: 1605 -VTKAKLQVFQR 1615
V K +++VF R
Sbjct: 202 KVVKLEVEVFAR 213
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 54.4 bits (125), Expect = 4e-06
Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIE-NKENRTTCT 1581
P F K I V E F+ G P PE++W+KD++ IR F I+ +++ +
Sbjct: 455 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 514
Query: 1582 IKKATKDLEGTYTCKAVSDIGLAVTKAK 1609
I D + YTCKAV+ +G A A+
Sbjct: 515 ISDVCGDDDAKYTCKAVNSLGEATCTAE 542
Score = 52.4 bits (120), Expect = 2e-05
Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Query: 1370 LNIEAYEYVPSVSEE--DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGI 1427
LN E E VS+ + +++EK V+ + + ++ L V EG R + K G
Sbjct: 427 LNAEKLESEEDVSQAFLEAVAEEKPH-VKPYFSKTIRDLEVV----EGSAARFDCKIEGY 481
Query: 1428 PKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIA 1487
P P+V W + + +S +QI+ +DG L + +V DD + +A N LG A
Sbjct: 482 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 541
Query: 1488 ALSVESI 1494
VE++
Sbjct: 542 EHIVETM 548
Score = 49.6 bits (113), Expect = 1e-04
Identities = 26/104 (25%), Positives = 45/104 (43%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P + + V++G +CKI G P P++ WF +++ I +R I + G C +
Sbjct: 455 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 514
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEED 1385
I + + Y C A N G+ + +E E EE+
Sbjct: 515 ISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGEGEEE 558
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 54.4 bits (125), Expect = 4e-06
Identities = 59/204 (28%), Positives = 85/204 (41%), Gaps = 40/204 (19%)
Query: 1237 LNVLEENISKDLIGVVTCRAEN-FAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMD 1295
L +L S D G+ C A N G+V + G+ V+ + P + P N +++
Sbjct: 84 LTILSVEDSDD--GIYCCTANNGVGGAVESCGALQVKMK-------PKITRPPINVKIIE 134
Query: 1296 GERISLNCKILGRPWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
G + L C +G P P + W + L E +R I+ +SG IH E AG Y+
Sbjct: 135 GLKAVLPCTTMGNPKPSVSWIKGDSPLRENSR---IAVLESGSLRIH--NVQKEDAGQYR 189
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C A N G AY V + +VE FA RI++A P T
Sbjct: 190 CVAKNSLG----------TAYSKVVKL------------EVEVFA-RILRA-PESHNVTF 225
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQG 1438
G + L A GIP P + W+ G
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENG 249
Score = 51.6 bits (118), Expect = 3e-05
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 33/225 (14%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
AP++ PLE + E + C + P P+I W N+ LI+ D S +++G +
Sbjct: 27 APVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLF-DTRYSIRENGQL-L 84
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTEC-ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
I GIY CTA+N G C L + +
Sbjct: 85 TILSVEDSDDGIYCCTANNGVGGAVESCGALQV------------------------KMK 120
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P+I + P V EG L +G PKP V W++ + L +++ +I L+ G+ L
Sbjct: 121 PKITRP-PINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENS--RIAVLESGS--L 175
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
+ V ++D G+ A N LG TA + +E V + R PE
Sbjct: 176 RIHNVQKEDAGQYRCVAKNSLG-TAYSKVVKLEVEVFARILRAPE 219
Score = 41.9 bits (94), Expect = 0.022
Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 9/121 (7%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ K+ G C A+N S+ T+ S +V+ + ++ A ++ AP E+ V G ++L+
Sbjct: 179 NVQKEDAGQYRCVAKN---SLGTAYSKVVKLE--VEVFARILRAP-ESHNVTFGSFVTLH 232
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C G P P I W N + + I S K + + + + F G+Y C A+N+ G
Sbjct: 233 CTATGIPVPTITWIENGNAVSSG-SIQES-VKDRVIDSRL-QLFITKPGLYTCIATNKHG 289
Query: 1363 K 1363
+
Sbjct: 290 E 290
Score = 39.5 bits (88), Expect = 0.12
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Query: 1537 EEIVTFEAIYSGNPTPEILWYKDNKVIRT-DERFIIENKENRTTCTIKKATKDLEGTYTC 1595
EE+ TF P PEI W ++ +I+ D R+ I +EN TI +G Y C
Sbjct: 42 EEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSI--RENGQLLTILSVEDSDDGIYCC 99
Query: 1596 KAVSDIGLAV 1605
A + +G AV
Sbjct: 100 TANNGVGGAV 109
Score = 36.7 bits (81), Expect = 0.81
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%)
Query: 1548 GNPTPEILWYKDNKVIRTDERF-IIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLA-- 1604
GNP P + W K + +R + R ++E+ R I K+ G Y C A + +G A
Sbjct: 146 GNPKPSVSWIKGDSPLRENSRIAVLESGSLR----IHNVQKEDAGQYRCVAKNSLGTAYS 201
Query: 1605 -VTKAKLQVFQR 1615
V K +++VF R
Sbjct: 202 KVVKLEVEVFAR 213
>U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein.
Length = 338
Score = 54.0 bits (124), Expect = 5e-06
Identities = 59/221 (26%), Positives = 89/221 (40%), Gaps = 38/221 (17%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
+ TV +G ++L C GRP P I W H L T R+ + + I E
Sbjct: 140 DVTVNEGSNVTLVCMANGRPEPVITWRH---LTPTGREFEGEEEY-----LEILGITREQ 191
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
+G Y+C A+N+ VS DV + T + + P I ++
Sbjct: 192 SGKYECKAANE--------------------VSSADVKQVKVTVN---YPPTITESKSNE 228
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
TT G+ L+ +A +P P W R T + + +I+ +G S LT+ V ++
Sbjct: 229 ATT--GRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKS-TEGQSSLTVTNVTEEHY 285
Query: 1470 GEIVFEAYNHLGVTATIAAL----SVESIVGTQEYRKPEWV 1506
G A N LGVT L SV I G+ P W+
Sbjct: 286 GNYTCVAANKLGVTNASLVLFRPGSVRGINGSISLAVPLWL 326
Score = 47.2 bits (107), Expect = 6e-04
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
+K T + P + E + + S P P+ WY+D+ I + I++ E
Sbjct: 211 VKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTE 270
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
+++ T+ T++ G YTC A + +G VT A L +F+
Sbjct: 271 GQSSLTVTNVTEEHYGNYTCVAANKLG--VTNASLVLFR 307
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 1247 DLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKIL 1306
+++G+ ++ + + SS +Q + + P + ++ G + SL C+
Sbjct: 183 EILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEAS 242
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P P +W+ ++ I +A + I + G + + E G Y C A+N+ G +
Sbjct: 243 AVPAPDFEWYRDDTRINSANGLEI-KSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNA 301
Query: 1367 ECIL 1370
+L
Sbjct: 302 SLVL 305
>BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associated
membrane protein protein.
Length = 338
Score = 54.0 bits (124), Expect = 5e-06
Identities = 59/221 (26%), Positives = 89/221 (40%), Gaps = 38/221 (17%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
+ TV +G ++L C GRP P I W H L T R+ + + I E
Sbjct: 140 DVTVNEGSNVTLVCMANGRPEPVITWRH---LTPTGREFEGEEEY-----LEILGITREQ 191
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
+G Y+C A+N+ VS DV + T + + P I ++
Sbjct: 192 SGKYECKAANE--------------------VSSADVKQVKVTVN---YPPTITESKSNE 228
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
TT G+ L+ +A +P P W R T + + +I+ +G S LT+ V ++
Sbjct: 229 ATT--GRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKS-TEGQSSLTVTNVTEEHY 285
Query: 1470 GEIVFEAYNHLGVTATIAAL----SVESIVGTQEYRKPEWV 1506
G A N LGVT L SV I G+ P W+
Sbjct: 286 GNYTCVAANKLGVTNASLVLFRPGSVRGINGSISLAVPLWL 326
Score = 47.2 bits (107), Expect = 6e-04
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
+K T + P + E + + S P P+ WY+D+ I + I++ E
Sbjct: 211 VKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTE 270
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
+++ T+ T++ G YTC A + +G VT A L +F+
Sbjct: 271 GQSSLTVTNVTEEHYGNYTCVAANKLG--VTNASLVLFR 307
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 1/124 (0%)
Query: 1247 DLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKIL 1306
+++G+ ++ + + SS +Q + + P + ++ G + SL C+
Sbjct: 183 EILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEAS 242
Query: 1307 GRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P P +W+ ++ I +A + I + G + + E G Y C A+N+ G +
Sbjct: 243 AVPAPDFEWYRDDTRINSANGLEI-KSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNA 301
Query: 1367 ECIL 1370
+L
Sbjct: 302 SLVL 305
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 53.6 bits (123), Expect = 7e-06
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 12/131 (9%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ + +G+ +C A+N AG +S + S V E P + PLE+ TV GE L
Sbjct: 664 NVKIEDMGIYSCMAQNTAGGLSANASLTVLE-------TPSFIRPLEDKTVTRGETAVLQ 716
Query: 1303 CKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C G P P+++W ++ L+ T R + + + I +A E AG Y C SN
Sbjct: 717 CIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQL----LIIVDAGLEDAGKYTCIMSNTL 772
Query: 1362 GKCSTECILNI 1372
G LN+
Sbjct: 773 GTERGHIYLNV 783
Score = 40.3 bits (90), Expect = 0.066
Identities = 47/204 (23%), Positives = 80/204 (39%), Gaps = 33/204 (16%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSI 1458
P +K P +T G + RLE A G P PQ+ W + G T+ + E ++
Sbjct: 602 PSFLKT-PMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH-------- 652
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
MPE DD I +G+ + +A + + A+L
Sbjct: 653 -VMPE---DDVFFIANVKIEDMGIYSCMAQNTAGGL----------------SANASLTV 692
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
++ P+F++ + + V E + I G+P P + W KD+ + ER N+
Sbjct: 693 LET-PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFA-AANQL 750
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIG 1602
+ +D G YTC + +G
Sbjct: 751 LIIVDAGLED-AGKYTCIMSNTLG 773
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 53.6 bits (123), Expect = 7e-06
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 12/131 (9%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ + +G+ +C A+N AG +S + S V E P + PLE+ TV GE L
Sbjct: 664 NVKIEDMGIYSCMAQNTAGGLSANASLTVLE-------TPSFIRPLEDKTVTRGETAVLQ 716
Query: 1303 CKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C G P P+++W ++ L+ T R + + + I +A E AG Y C SN
Sbjct: 717 CIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQL----LIIVDAGLEDAGKYTCIMSNTL 772
Query: 1362 GKCSTECILNI 1372
G LN+
Sbjct: 773 GTERGHIYLNV 783
Score = 40.3 bits (90), Expect = 0.066
Identities = 47/204 (23%), Positives = 80/204 (39%), Gaps = 33/204 (16%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSI 1458
P +K P +T G + RLE A G P PQ+ W + G T+ + E ++
Sbjct: 602 PSFLKT-PMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH-------- 652
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
MPE DD I +G+ + +A + + A+L
Sbjct: 653 -VMPE---DDVFFIANVKIEDMGIYSCMAQNTAGGL----------------SANASLTV 692
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
++ P+F++ + + V E + I G+P P + W KD+ + ER N+
Sbjct: 693 LET-PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFA-AANQL 750
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIG 1602
+ +D G YTC + +G
Sbjct: 751 LIIVDAGLED-AGKYTCIMSNTLG 773
>AL603911-1|CAI14448.1| 721|Homo sapiens triadin protein.
Length = 721
Score = 53.6 bits (123), Expect = 7e-06
Identities = 73/284 (25%), Positives = 120/284 (42%), Gaps = 33/284 (11%)
Query: 234 KTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEK-E 292
+ EI KDK E++ + E K Q+ + K++ K+K+ +E K K IEK E
Sbjct: 139 RKKEIHKDKTEKQEK-PERKIQTKVTHKEKEKGKEKV---REKEKPEKKATHKEKIEKKE 194
Query: 293 KIEDVALKPVRKDSLMDEKSSEISELQNE-------RQITEKKESLQETQLQPTEKNKLL 345
K E L +K + EKS E ++ + + +Q K + +Q+T +P EK
Sbjct: 195 KPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEK---- 250
Query: 346 ENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKET 405
++ K + K Q++ Q + ++ P L TE+ S+ T
Sbjct: 251 ----EDKEKAAVSKHEQKD---QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPT 303
Query: 406 --EDRINTK--DTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEIT 461
+ K + +K T E K ++K EKE D+ K K S + T
Sbjct: 304 PASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKS-EKETAIDVEKKEPGKASETKQGT 362
Query: 462 EEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEE 505
++ A +A D +KE+ K K P E + P GK+Q K+E
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTK-----KPAEVEQPKGKKQEKKE 401
Score = 44.8 bits (101), Expect = 0.003
Identities = 99/381 (25%), Positives = 151/381 (39%), Gaps = 34/381 (8%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTN----------ILKVENLESVNVDTTSS 197
KV+EV +T KPK E K+ VS HE + I +L+
Sbjct: 236 KVKEVQKTP--SKPKE-KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292
Query: 198 KLETKSWRKPR-LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS 256
L T+ +P +LEE K E +V K K E +K K+E+E + KK+
Sbjct: 293 PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEP 352
Query: 257 TKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEIS 316
KA E K + KI Q A K + K E S K+ E +P K EK E +
Sbjct: 353 GKASETK-QGTVKIA-AQAAAK-KDEKKEDSKKTKKPAE--VEQPKGKKQEKKEKHVEPA 407
Query: 317 EL-QNERQITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALK 374
+ + E + K+ +T+ E + ++ V + +E T K ++E +KE + K
Sbjct: 408 KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQE--IRKEKSGK 465
Query: 375 TVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTR--KPSIPWTQEAIKLRP-- 430
T + P EKE + +D +K + KP P Q + +P
Sbjct: 466 TSSILKDKEPIKGKEEKV-PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP 524
Query: 431 -TKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSA-LDDIEK-EEHKPDKVSEN 487
K E P EK + + + V E LK IEK + KP K +E+
Sbjct: 525 QIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEH 584
Query: 488 NAPEERKWPTGKRQPKEETPQ 508
ER+ P+ K + TP+
Sbjct: 585 ---REREPPSIKTDKPKPTPK 602
Score = 41.5 bits (93), Expect = 0.029
Identities = 84/372 (22%), Positives = 145/372 (38%), Gaps = 39/372 (10%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
E K +E ++ K ++ EKK+ + S + + K+ + D K ++K
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTV-KIAAQAAAKKD--EKKEDSKK 382
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS-----TK 258
+KP E + G + E V + PK + + + + + K++ K
Sbjct: 383 TKKPAEVE--QPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKK 440
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKV-----EKSPIE-KEKIEDVALKPVRKDSLMDEKS 312
A+ K E K QE K + K +K PI+ KE+ +LK ++ DEK
Sbjct: 441 AVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKM 500
Query: 313 SEISELQNER--QITEKKESLQETQLQPTEKNKLLENIVSEESK----ESTGKRRQREEI 366
S+ + + Q+ KKE E Q++ K + E + + E T + EE
Sbjct: 501 SKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEK 560
Query: 367 TQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAI 426
K+V T+ KP T + E +E E D KP+ T E
Sbjct: 561 VLKQVKAVTIEKTA------------KPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVT 608
Query: 427 KLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIE--KEEHKPDKV 484
+ K E + EKE E +K R++ V E + +D+E K +
Sbjct: 609 ESGKKKTEIS--EKESKEKADMKHLREEK-VSTRKESLQLHNVTKEDVEDVPASKKAKEG 665
Query: 485 SENNAPEERKWP 496
+E+ +P ++K P
Sbjct: 666 TEDVSPTKQKSP 677
Score = 41.1 bits (92), Expect = 0.038
Identities = 76/344 (22%), Positives = 137/344 (39%), Gaps = 24/344 (6%)
Query: 43 STSTKKVEPTTGKASYSTTEETNMLKVENIQDTETKNITTVPWRKREQLDMHFKKEDTLE 102
S + ++ E KA T ET + E+I+ K T + K+E K+ T++
Sbjct: 306 SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKE-TAIDVEKKEPGKASETKQGTVK 364
Query: 103 IKHWRRSRPEQNKDTEHTSMIGXXXXXXXXXXXXVFERGVIE-EHVKVQEVVETKLWRKP 161
I ++ ++ K+ + E+ V + K + V + K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKA 424
Query: 162 KTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKG 221
KT K+++ VS + K E T + + E + + + L++ P KG
Sbjct: 425 KTERAKEEIGAVSIKKAVPGKKEEKT------TKTVEQEIRKEKSGKTSSILKDKEPIKG 478
Query: 222 VNE--PEVCHWRKPKTSEILK-DKNEEEIRVQ----EMKKQSTKALEVKDESKQKIPWTQ 274
E P ++P+T + K K +E++ + + KK+ ++K E+K I
Sbjct: 479 KEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKV 538
Query: 275 EAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSL------MDEKSSEISELQNERQITEKK 328
+ K K EK+ + K E+ LK V+ ++ K +E E + T+K
Sbjct: 539 QIHKQDIVKPEKT-VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKP 597
Query: 329 ESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREE--ITQKE 370
+ + + TE K I +ESKE + REE T+KE
Sbjct: 598 KPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
>AL603902-1|CAH70824.1| 721|Homo sapiens triadin protein.
Length = 721
Score = 53.6 bits (123), Expect = 7e-06
Identities = 73/284 (25%), Positives = 120/284 (42%), Gaps = 33/284 (11%)
Query: 234 KTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEK-E 292
+ EI KDK E++ + E K Q+ + K++ K+K+ +E K K IEK E
Sbjct: 139 RKKEIHKDKTEKQEK-PERKIQTKVTHKEKEKGKEKV---REKEKPEKKATHKEKIEKKE 194
Query: 293 KIEDVALKPVRKDSLMDEKSSEISELQNE-------RQITEKKESLQETQLQPTEKNKLL 345
K E L +K + EKS E ++ + + +Q K + +Q+T +P EK
Sbjct: 195 KPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEK---- 250
Query: 346 ENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKET 405
++ K + K Q++ Q + ++ P L TE+ S+ T
Sbjct: 251 ----EDKEKAAVSKHEQKD---QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPT 303
Query: 406 --EDRINTK--DTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEIT 461
+ K + +K T E K ++K EKE D+ K K S + T
Sbjct: 304 PASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKS-EKETAIDVEKKEPGKASETKQGT 362
Query: 462 EEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEE 505
++ A +A D +KE+ K K P E + P GK+Q K+E
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTK-----KPAEVEQPKGKKQEKKE 401
Score = 44.8 bits (101), Expect = 0.003
Identities = 99/381 (25%), Positives = 151/381 (39%), Gaps = 34/381 (8%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTN----------ILKVENLESVNVDTTSS 197
KV+EV +T KPK E K+ VS HE + I +L+
Sbjct: 236 KVKEVQKTP--SKPKE-KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292
Query: 198 KLETKSWRKPR-LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS 256
L T+ +P +LEE K E +V K K E +K K+E+E + KK+
Sbjct: 293 PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEP 352
Query: 257 TKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEIS 316
KA E K + KI Q A K + K E S K+ E +P K EK E +
Sbjct: 353 GKASETK-QGTVKIA-AQAAAK-KDEKKEDSKKTKKPAE--VEQPKGKKQEKKEKHVEPA 407
Query: 317 EL-QNERQITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALK 374
+ + E + K+ +T+ E + ++ V + +E T K ++E +KE + K
Sbjct: 408 KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQE--IRKEKSGK 465
Query: 375 TVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTR--KPSIPWTQEAIKLRP-- 430
T + P EKE + +D +K + KP P Q + +P
Sbjct: 466 TSSILKDKEPIKGKEEKV-PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP 524
Query: 431 -TKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSA-LDDIEK-EEHKPDKVSEN 487
K E P EK + + + V E LK IEK + KP K +E+
Sbjct: 525 QIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEH 584
Query: 488 NAPEERKWPTGKRQPKEETPQ 508
ER+ P+ K + TP+
Sbjct: 585 ---REREPPSIKTDKPKPTPK 602
Score = 41.5 bits (93), Expect = 0.029
Identities = 84/372 (22%), Positives = 145/372 (38%), Gaps = 39/372 (10%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
E K +E ++ K ++ EKK+ + S + + K+ + D K ++K
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTV-KIAAQAAAKKD--EKKEDSKK 382
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS-----TK 258
+KP E + G + E V + PK + + + + + K++ K
Sbjct: 383 TKKPAEVE--QPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKK 440
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKV-----EKSPIE-KEKIEDVALKPVRKDSLMDEKS 312
A+ K E K QE K + K +K PI+ KE+ +LK ++ DEK
Sbjct: 441 AVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKM 500
Query: 313 SEISELQNER--QITEKKESLQETQLQPTEKNKLLENIVSEESK----ESTGKRRQREEI 366
S+ + + Q+ KKE E Q++ K + E + + E T + EE
Sbjct: 501 SKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEK 560
Query: 367 TQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAI 426
K+V T+ KP T + E +E E D KP+ T E
Sbjct: 561 VLKQVKAVTIEKTA------------KPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVT 608
Query: 427 KLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIE--KEEHKPDKV 484
+ K E + EKE E +K R++ V E + +D+E K +
Sbjct: 609 ESGKKKTEIS--EKESKEKADMKHLREEK-VSTRKESLQLHNVTKEDVEDVPASKKAKEG 665
Query: 485 SENNAPEERKWP 496
+E+ +P ++K P
Sbjct: 666 TEDVSPTKQKSP 677
Score = 41.1 bits (92), Expect = 0.038
Identities = 76/344 (22%), Positives = 137/344 (39%), Gaps = 24/344 (6%)
Query: 43 STSTKKVEPTTGKASYSTTEETNMLKVENIQDTETKNITTVPWRKREQLDMHFKKEDTLE 102
S + ++ E KA T ET + E+I+ K T + K+E K+ T++
Sbjct: 306 SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKE-TAIDVEKKEPGKASETKQGTVK 364
Query: 103 IKHWRRSRPEQNKDTEHTSMIGXXXXXXXXXXXXVFERGVIE-EHVKVQEVVETKLWRKP 161
I ++ ++ K+ + E+ V + K + V + K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKA 424
Query: 162 KTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKG 221
KT K+++ VS + K E T + + E + + + L++ P KG
Sbjct: 425 KTERAKEEIGAVSIKKAVPGKKEEKT------TKTVEQEIRKEKSGKTSSILKDKEPIKG 478
Query: 222 VNE--PEVCHWRKPKTSEILK-DKNEEEIRVQ----EMKKQSTKALEVKDESKQKIPWTQ 274
E P ++P+T + K K +E++ + + KK+ ++K E+K I
Sbjct: 479 KEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKV 538
Query: 275 EAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSL------MDEKSSEISELQNERQITEKK 328
+ K K EK+ + K E+ LK V+ ++ K +E E + T+K
Sbjct: 539 QIHKQDIVKPEKT-VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKP 597
Query: 329 ESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREE--ITQKE 370
+ + + TE K I +ESKE + REE T+KE
Sbjct: 598 KPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
>AL445259-1|CAI41045.1| 721|Homo sapiens triadin protein.
Length = 721
Score = 53.6 bits (123), Expect = 7e-06
Identities = 73/284 (25%), Positives = 120/284 (42%), Gaps = 33/284 (11%)
Query: 234 KTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEK-E 292
+ EI KDK E++ + E K Q+ + K++ K+K+ +E K K IEK E
Sbjct: 139 RKKEIHKDKTEKQEK-PERKIQTKVTHKEKEKGKEKV---REKEKPEKKATHKEKIEKKE 194
Query: 293 KIEDVALKPVRKDSLMDEKSSEISELQNE-------RQITEKKESLQETQLQPTEKNKLL 345
K E L +K + EKS E ++ + + +Q K + +Q+T +P EK
Sbjct: 195 KPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEK---- 250
Query: 346 ENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKET 405
++ K + K Q++ Q + ++ P L TE+ S+ T
Sbjct: 251 ----EDKEKAAVSKHEQKD---QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPT 303
Query: 406 --EDRINTK--DTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEIT 461
+ K + +K T E K ++K EKE D+ K K S + T
Sbjct: 304 PASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKS-EKETAIDVEKKEPGKASETKQGT 362
Query: 462 EEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEE 505
++ A +A D +KE+ K K P E + P GK+Q K+E
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTK-----KPAEVEQPKGKKQEKKE 401
Score = 44.8 bits (101), Expect = 0.003
Identities = 99/381 (25%), Positives = 151/381 (39%), Gaps = 34/381 (8%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTN----------ILKVENLESVNVDTTSS 197
KV+EV +T KPK E K+ VS HE + I +L+
Sbjct: 236 KVKEVQKTP--SKPKE-KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292
Query: 198 KLETKSWRKPR-LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS 256
L T+ +P +LEE K E +V K K E +K K+E+E + KK+
Sbjct: 293 PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEP 352
Query: 257 TKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEIS 316
KA E K + KI Q A K + K E S K+ E +P K EK E +
Sbjct: 353 GKASETK-QGTVKIA-AQAAAK-KDEKKEDSKKTKKPAE--VEQPKGKKQEKKEKHVEPA 407
Query: 317 EL-QNERQITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALK 374
+ + E + K+ +T+ E + ++ V + +E T K ++E +KE + K
Sbjct: 408 KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQE--IRKEKSGK 465
Query: 375 TVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTR--KPSIPWTQEAIKLRP-- 430
T + P EKE + +D +K + KP P Q + +P
Sbjct: 466 TSSILKDKEPIKGKEEKV-PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP 524
Query: 431 -TKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSA-LDDIEK-EEHKPDKVSEN 487
K E P EK + + + V E LK IEK + KP K +E+
Sbjct: 525 QIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEH 584
Query: 488 NAPEERKWPTGKRQPKEETPQ 508
ER+ P+ K + TP+
Sbjct: 585 ---REREPPSIKTDKPKPTPK 602
Score = 41.5 bits (93), Expect = 0.029
Identities = 84/372 (22%), Positives = 145/372 (38%), Gaps = 39/372 (10%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
E K +E ++ K ++ EKK+ + S + + K+ + D K ++K
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTV-KIAAQAAAKKD--EKKEDSKK 382
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS-----TK 258
+KP E + G + E V + PK + + + + + K++ K
Sbjct: 383 TKKPAEVE--QPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKK 440
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKV-----EKSPIE-KEKIEDVALKPVRKDSLMDEKS 312
A+ K E K QE K + K +K PI+ KE+ +LK ++ DEK
Sbjct: 441 AVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKM 500
Query: 313 SEISELQNER--QITEKKESLQETQLQPTEKNKLLENIVSEESK----ESTGKRRQREEI 366
S+ + + Q+ KKE E Q++ K + E + + E T + EE
Sbjct: 501 SKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEK 560
Query: 367 TQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAI 426
K+V T+ KP T + E +E E D KP+ T E
Sbjct: 561 VLKQVKAVTIEKTA------------KPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVT 608
Query: 427 KLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIE--KEEHKPDKV 484
+ K E + EKE E +K R++ V E + +D+E K +
Sbjct: 609 ESGKKKTEIS--EKESKEKADMKHLREEK-VSTRKESLQLHNVTKEDVEDVPASKKAKEG 665
Query: 485 SENNAPEERKWP 496
+E+ +P ++K P
Sbjct: 666 TEDVSPTKQKSP 677
Score = 41.1 bits (92), Expect = 0.038
Identities = 76/344 (22%), Positives = 137/344 (39%), Gaps = 24/344 (6%)
Query: 43 STSTKKVEPTTGKASYSTTEETNMLKVENIQDTETKNITTVPWRKREQLDMHFKKEDTLE 102
S + ++ E KA T ET + E+I+ K T + K+E K+ T++
Sbjct: 306 SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKE-TAIDVEKKEPGKASETKQGTVK 364
Query: 103 IKHWRRSRPEQNKDTEHTSMIGXXXXXXXXXXXXVFERGVIE-EHVKVQEVVETKLWRKP 161
I ++ ++ K+ + E+ V + K + V + K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKA 424
Query: 162 KTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKG 221
KT K+++ VS + K E T + + E + + + L++ P KG
Sbjct: 425 KTERAKEEIGAVSIKKAVPGKKEEKT------TKTVEQEIRKEKSGKTSSILKDKEPIKG 478
Query: 222 VNE--PEVCHWRKPKTSEILK-DKNEEEIRVQ----EMKKQSTKALEVKDESKQKIPWTQ 274
E P ++P+T + K K +E++ + + KK+ ++K E+K I
Sbjct: 479 KEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKV 538
Query: 275 EAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSL------MDEKSSEISELQNERQITEKK 328
+ K K EK+ + K E+ LK V+ ++ K +E E + T+K
Sbjct: 539 QIHKQDIVKPEKT-VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKP 597
Query: 329 ESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREE--ITQKE 370
+ + + TE K I +ESKE + REE T+KE
Sbjct: 598 KPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
>AL357352-1|CAI16757.1| 721|Homo sapiens triadin protein.
Length = 721
Score = 53.6 bits (123), Expect = 7e-06
Identities = 73/284 (25%), Positives = 120/284 (42%), Gaps = 33/284 (11%)
Query: 234 KTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEK-E 292
+ EI KDK E++ + E K Q+ + K++ K+K+ +E K K IEK E
Sbjct: 139 RKKEIHKDKTEKQEK-PERKIQTKVTHKEKEKGKEKV---REKEKPEKKATHKEKIEKKE 194
Query: 293 KIEDVALKPVRKDSLMDEKSSEISELQNE-------RQITEKKESLQETQLQPTEKNKLL 345
K E L +K + EKS E ++ + + +Q K + +Q+T +P EK
Sbjct: 195 KPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEK---- 250
Query: 346 ENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKET 405
++ K + K Q++ Q + ++ P L TE+ S+ T
Sbjct: 251 ----EDKEKAAVSKHEQKD---QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPT 303
Query: 406 --EDRINTK--DTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEIT 461
+ K + +K T E K ++K EKE D+ K K S + T
Sbjct: 304 PASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKS-EKETAIDVEKKEPGKASETKQGT 362
Query: 462 EEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEE 505
++ A +A D +KE+ K K P E + P GK+Q K+E
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTK-----KPAEVEQPKGKKQEKKE 401
Score = 44.8 bits (101), Expect = 0.003
Identities = 99/381 (25%), Positives = 151/381 (39%), Gaps = 34/381 (8%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTN----------ILKVENLESVNVDTTSS 197
KV+EV +T KPK E K+ VS HE + I +L+
Sbjct: 236 KVKEVQKTP--SKPKE-KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292
Query: 198 KLETKSWRKPR-LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS 256
L T+ +P +LEE K E +V K K E +K K+E+E + KK+
Sbjct: 293 PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEP 352
Query: 257 TKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEIS 316
KA E K + KI Q A K + K E S K+ E +P K EK E +
Sbjct: 353 GKASETK-QGTVKIA-AQAAAK-KDEKKEDSKKTKKPAE--VEQPKGKKQEKKEKHVEPA 407
Query: 317 EL-QNERQITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALK 374
+ + E + K+ +T+ E + ++ V + +E T K ++E +KE + K
Sbjct: 408 KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQE--IRKEKSGK 465
Query: 375 TVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTR--KPSIPWTQEAIKLRP-- 430
T + P EKE + +D +K + KP P Q + +P
Sbjct: 466 TSSILKDKEPIKGKEEKV-PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP 524
Query: 431 -TKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSA-LDDIEK-EEHKPDKVSEN 487
K E P EK + + + V E LK IEK + KP K +E+
Sbjct: 525 QIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEH 584
Query: 488 NAPEERKWPTGKRQPKEETPQ 508
ER+ P+ K + TP+
Sbjct: 585 ---REREPPSIKTDKPKPTPK 602
Score = 41.5 bits (93), Expect = 0.029
Identities = 84/372 (22%), Positives = 145/372 (38%), Gaps = 39/372 (10%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
E K +E ++ K ++ EKK+ + S + + K+ + D K ++K
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTV-KIAAQAAAKKD--EKKEDSKK 382
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS-----TK 258
+KP E + G + E V + PK + + + + + K++ K
Sbjct: 383 TKKPAEVE--QPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKK 440
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKV-----EKSPIE-KEKIEDVALKPVRKDSLMDEKS 312
A+ K E K QE K + K +K PI+ KE+ +LK ++ DEK
Sbjct: 441 AVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKM 500
Query: 313 SEISELQNER--QITEKKESLQETQLQPTEKNKLLENIVSEESK----ESTGKRRQREEI 366
S+ + + Q+ KKE E Q++ K + E + + E T + EE
Sbjct: 501 SKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEK 560
Query: 367 TQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAI 426
K+V T+ KP T + E +E E D KP+ T E
Sbjct: 561 VLKQVKAVTIEKTA------------KPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVT 608
Query: 427 KLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIE--KEEHKPDKV 484
+ K E + EKE E +K R++ V E + +D+E K +
Sbjct: 609 ESGKKKTEIS--EKESKEKADMKHLREEK-VSTRKESLQLHNVTKEDVEDVPASKKAKEG 665
Query: 485 SENNAPEERKWP 496
+E+ +P ++K P
Sbjct: 666 TEDVSPTKQKSP 677
Score = 41.1 bits (92), Expect = 0.038
Identities = 76/344 (22%), Positives = 137/344 (39%), Gaps = 24/344 (6%)
Query: 43 STSTKKVEPTTGKASYSTTEETNMLKVENIQDTETKNITTVPWRKREQLDMHFKKEDTLE 102
S + ++ E KA T ET + E+I+ K T + K+E K+ T++
Sbjct: 306 SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKE-TAIDVEKKEPGKASETKQGTVK 364
Query: 103 IKHWRRSRPEQNKDTEHTSMIGXXXXXXXXXXXXVFERGVIE-EHVKVQEVVETKLWRKP 161
I ++ ++ K+ + E+ V + K + V + K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKA 424
Query: 162 KTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKG 221
KT K+++ VS + K E T + + E + + + L++ P KG
Sbjct: 425 KTERAKEEIGAVSIKKAVPGKKEEKT------TKTVEQEIRKEKSGKTSSILKDKEPIKG 478
Query: 222 VNE--PEVCHWRKPKTSEILK-DKNEEEIRVQ----EMKKQSTKALEVKDESKQKIPWTQ 274
E P ++P+T + K K +E++ + + KK+ ++K E+K I
Sbjct: 479 KEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKV 538
Query: 275 EAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSL------MDEKSSEISELQNERQITEKK 328
+ K K EK+ + K E+ LK V+ ++ K +E E + T+K
Sbjct: 539 QIHKQDIVKPEKT-VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKP 597
Query: 329 ESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREE--ITQKE 370
+ + + TE K I +ESKE + REE T+KE
Sbjct: 598 KPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 53.6 bits (123), Expect = 7e-06
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 12/131 (9%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ + +G+ +C A+N AG +S + S V E P + PLE+ TV GE L
Sbjct: 664 NVKIEDMGIYSCMAQNTAGGLSANASLTVLE-------TPSFIRPLEDKTVTRGETAVLQ 716
Query: 1303 CKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C G P P+++W ++ L+ T R + + + I +A E AG Y C SN
Sbjct: 717 CIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQL----LIIVDAGLEDAGKYTCIMSNTL 772
Query: 1362 GKCSTECILNI 1372
G LN+
Sbjct: 773 GTERGHIYLNV 783
Score = 40.3 bits (90), Expect = 0.066
Identities = 47/204 (23%), Positives = 80/204 (39%), Gaps = 33/204 (16%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSI 1458
P +K P +T G + RLE A G P PQ+ W + G T+ + E ++
Sbjct: 602 PSFLKT-PMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH-------- 652
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
MPE DD I +G+ + +A + + A+L
Sbjct: 653 -VMPE---DDVFFIANVKIEDMGIYSCMAQNTAGGL----------------SANASLTV 692
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
++ P+F++ + + V E + I G+P P + W KD+ + ER N+
Sbjct: 693 LET-PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFA-AANQL 750
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIG 1602
+ +D G YTC + +G
Sbjct: 751 LIIVDAGLED-AGKYTCIMSNTLG 773
>AL133257-1|CAI19636.1| 721|Homo sapiens triadin protein.
Length = 721
Score = 53.6 bits (123), Expect = 7e-06
Identities = 73/284 (25%), Positives = 120/284 (42%), Gaps = 33/284 (11%)
Query: 234 KTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEK-E 292
+ EI KDK E++ + E K Q+ + K++ K+K+ +E K K IEK E
Sbjct: 139 RKKEIHKDKTEKQEK-PERKIQTKVTHKEKEKGKEKV---REKEKPEKKATHKEKIEKKE 194
Query: 293 KIEDVALKPVRKDSLMDEKSSEISELQNE-------RQITEKKESLQETQLQPTEKNKLL 345
K E L +K + EKS E ++ + + +Q K + +Q+T +P EK
Sbjct: 195 KPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEK---- 250
Query: 346 ENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKET 405
++ K + K Q++ Q + ++ P L TE+ S+ T
Sbjct: 251 ----EDKEKAAVSKHEQKD---QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPT 303
Query: 406 --EDRINTK--DTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEIT 461
+ K + +K T E K ++K EKE D+ K K S + T
Sbjct: 304 PASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKS-EKETAIDVEKKEPGKASETKQGT 362
Query: 462 EEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEE 505
++ A +A D +KE+ K K P E + P GK+Q K+E
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTK-----KPAEVEQPKGKKQEKKE 401
Score = 44.8 bits (101), Expect = 0.003
Identities = 99/381 (25%), Positives = 151/381 (39%), Gaps = 34/381 (8%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTN----------ILKVENLESVNVDTTSS 197
KV+EV +T KPK E K+ VS HE + I +L+
Sbjct: 236 KVKEVQKTP--SKPKE-KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292
Query: 198 KLETKSWRKPR-LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS 256
L T+ +P +LEE K E +V K K E +K K+E+E + KK+
Sbjct: 293 PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEP 352
Query: 257 TKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEIS 316
KA E K + KI Q A K + K E S K+ E +P K EK E +
Sbjct: 353 GKASETK-QGTVKIA-AQAAAK-KDEKKEDSKKTKKPAE--VEQPKGKKQEKKEKHVEPA 407
Query: 317 EL-QNERQITEKKESLQETQLQPTEKNKL-LENIVSEESKESTGKRRQREEITQKEVALK 374
+ + E + K+ +T+ E + ++ V + +E T K ++E +KE + K
Sbjct: 408 KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQE--IRKEKSGK 465
Query: 375 TVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTR--KPSIPWTQEAIKLRP-- 430
T + P EKE + +D +K + KP P Q + +P
Sbjct: 466 TSSILKDKEPIKGKEEKV-PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP 524
Query: 431 -TKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSA-LDDIEK-EEHKPDKVSEN 487
K E P EK + + + V E LK IEK + KP K +E+
Sbjct: 525 QIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEH 584
Query: 488 NAPEERKWPTGKRQPKEETPQ 508
ER+ P+ K + TP+
Sbjct: 585 ---REREPPSIKTDKPKPTPK 602
Score = 41.5 bits (93), Expect = 0.029
Identities = 84/372 (22%), Positives = 145/372 (38%), Gaps = 39/372 (10%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
E K +E ++ K ++ EKK+ + S + + K+ + D K ++K
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTV-KIAAQAAAKKD--EKKEDSKK 382
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS-----TK 258
+KP E + G + E V + PK + + + + + K++ K
Sbjct: 383 TKKPAEVE--QPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKK 440
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKV-----EKSPIE-KEKIEDVALKPVRKDSLMDEKS 312
A+ K E K QE K + K +K PI+ KE+ +LK ++ DEK
Sbjct: 441 AVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKM 500
Query: 313 SEISELQNER--QITEKKESLQETQLQPTEKNKLLENIVSEESK----ESTGKRRQREEI 366
S+ + + Q+ KKE E Q++ K + E + + E T + EE
Sbjct: 501 SKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEK 560
Query: 367 TQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAI 426
K+V T+ KP T + E +E E D KP+ T E
Sbjct: 561 VLKQVKAVTIEKTA------------KPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVT 608
Query: 427 KLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIE--KEEHKPDKV 484
+ K E + EKE E +K R++ V E + +D+E K +
Sbjct: 609 ESGKKKTEIS--EKESKEKADMKHLREEK-VSTRKESLQLHNVTKEDVEDVPASKKAKEG 665
Query: 485 SENNAPEERKWP 496
+E+ +P ++K P
Sbjct: 666 TEDVSPTKQKSP 677
Score = 41.1 bits (92), Expect = 0.038
Identities = 76/344 (22%), Positives = 137/344 (39%), Gaps = 24/344 (6%)
Query: 43 STSTKKVEPTTGKASYSTTEETNMLKVENIQDTETKNITTVPWRKREQLDMHFKKEDTLE 102
S + ++ E KA T ET + E+I+ K T + K+E K+ T++
Sbjct: 306 SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKE-TAIDVEKKEPGKASETKQGTVK 364
Query: 103 IKHWRRSRPEQNKDTEHTSMIGXXXXXXXXXXXXVFERGVIE-EHVKVQEVVETKLWRKP 161
I ++ ++ K+ + E+ V + K + V + K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKA 424
Query: 162 KTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKG 221
KT K+++ VS + K E T + + E + + + L++ P KG
Sbjct: 425 KTERAKEEIGAVSIKKAVPGKKEEKT------TKTVEQEIRKEKSGKTSSILKDKEPIKG 478
Query: 222 VNE--PEVCHWRKPKTSEILK-DKNEEEIRVQ----EMKKQSTKALEVKDESKQKIPWTQ 274
E P ++P+T + K K +E++ + + KK+ ++K E+K I
Sbjct: 479 KEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKV 538
Query: 275 EAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSL------MDEKSSEISELQNERQITEKK 328
+ K K EK+ + K E+ LK V+ ++ K +E E + T+K
Sbjct: 539 QIHKQDIVKPEKT-VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKP 597
Query: 329 ESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREE--ITQKE 370
+ + + TE K I +ESKE + REE T+KE
Sbjct: 598 KPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
>AC115538-1|AAY40987.1| 103|Homo sapiens unknown protein.
Length = 103
Score = 53.6 bits (123), Expect = 7e-06
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDW-FHNEKLIETARDITISRQKSGLCEI 1340
P+ + L+NT V DG + L C++LG P P+I W NE L + +++ + G +
Sbjct: 7 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 66
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAY 1375
I+ A E AG Y +A N+ G S C ++ Y
Sbjct: 67 LIQGATKEDAGWYTVSAKNEAGIVS--CTARLDVY 99
Score = 44.4 bits (100), Expect = 0.004
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDTGEI 1472
+G +RLE + +G+P PQ+ W ++ L ST+ + + + G L + ++D G
Sbjct: 20 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 79
Query: 1473 VFEAYNHLGVTATIAALSV 1491
A N G+ + A L V
Sbjct: 80 TVSAKNEAGIVSCTARLDV 98
Score = 44.0 bits (99), Expect = 0.005
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 1517 KATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI--RTDERFIIENK 1574
K P F++++ V + V E G P P+I W K+N+ + TD + ++
Sbjct: 1 KEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDN 60
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVF 1613
I+ ATK+ G YT A ++ G+ A+L V+
Sbjct: 61 HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 99
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 53.6 bits (123), Expect = 7e-06
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 12/131 (9%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N+ + +G+ +C A+N AG +S + S V E P + PLE+ TV GE L
Sbjct: 672 NVKIEDMGIYSCMAQNTAGGLSANASLTVLE-------TPSFIRPLEDKTVTRGETAVLQ 724
Query: 1303 CKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C G P P+++W ++ L+ T R + + + I +A E AG Y C SN
Sbjct: 725 CIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQL----LIIVDAGLEDAGKYTCIMSNTL 780
Query: 1362 GKCSTECILNI 1372
G LN+
Sbjct: 781 GTERGHIYLNV 791
Score = 40.3 bits (90), Expect = 0.066
Identities = 47/204 (23%), Positives = 80/204 (39%), Gaps = 33/204 (16%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSI 1458
P +K P +T G + RLE A G P PQ+ W + G T+ + E ++
Sbjct: 610 PSFLKT-PMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH-------- 660
Query: 1459 LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKA 1518
MPE DD I +G+ + +A + + A+L
Sbjct: 661 -VMPE---DDVFFIANVKIEDMGIYSCMAQNTAGGL----------------SANASLTV 700
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRT 1578
++ P+F++ + + V E + I G+P P + W KD+ + ER N+
Sbjct: 701 LET-PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFA-AANQL 758
Query: 1579 TCTIKKATKDLEGTYTCKAVSDIG 1602
+ +D G YTC + +G
Sbjct: 759 LIIVDAGLED-AGKYTCIMSNTLG 781
>AL390252-10|CAI13179.1| 354|Homo sapiens myosin binding protein
H-like protein.
Length = 354
Score = 53.2 bits (122), Expect = 9e-06
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
+AP PL + T + G L C + P PKI W N+ I+ + G+C
Sbjct: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR-ALTHLGICS 317
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ I++ P GIY C A N G+ S +C ++++
Sbjct: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
Score = 34.3 bits (75), Expect = 4.3
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 1549 NPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKA 1608
+P P+I+W K+ I+ + ++ + I+K G YTCKAV+ +G A
Sbjct: 287 SPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
Query: 1609 KLQV 1612
++ V
Sbjct: 347 RVDV 350
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens
cDNA FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 53.2 bits (122), Expect = 9e-06
Identities = 79/373 (21%), Positives = 166/373 (44%), Gaps = 22/373 (5%)
Query: 143 IEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLE-SVNVDTTSSKLET 201
IEE K ++ + +L+R T E K+ E +++ E E +NV KLE
Sbjct: 189 IEELTKERDALSLELYRNTITDEELKEK-NAKLQEKLQLVESEKSEIQLNVKELKRKLER 247
Query: 202 KSWRKPR--LEESLEEVGPT-KGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTK 258
P+ L+ + +G + V+ + + L + EE++ QE K Q +
Sbjct: 248 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 307
Query: 259 ALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISEL 318
E E ++KI +E I+ + K+ + ++E + + K R++ +M EK ++ L
Sbjct: 308 --EKIQEQEEKIREQEEKIREQEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEKMRRL 362
Query: 319 QNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRX 378
E + EK+E ++E + + E+ K+ E EE ++ K R++E+ ++E K R
Sbjct: 363 --EEMMWEKEEKIRELEEKMHEQEKIRE---QEEKRQEEEKIREQEKRQEQEA--KMWRQ 415
Query: 379 XXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIP-WTQEAIKLRPTKMEKTP 437
+ + ++E +++I ++ R+ W QE K+R + E+
Sbjct: 416 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE-KIR--EQEEIW 472
Query: 438 IEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPT 497
+KEK + K +++ V E++ + + + E++ + ++ + R+
Sbjct: 473 RQKEKMHE-QEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 531
Query: 498 GKRQPKEETPQEE 510
R+ KE+ ++E
Sbjct: 532 KIREQKEKIREQE 544
Score = 50.0 bits (114), Expect = 8e-05
Identities = 53/233 (22%), Positives = 112/233 (48%), Gaps = 17/233 (7%)
Query: 139 ERGVIEEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHED-TNILKVENLESVNVDTTSS 197
E I E K QE E K+WR+ + I E+++ ++ + K+ E + +
Sbjct: 395 EEEKIREQEKRQEQ-EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 453
Query: 198 KLETKSWRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDK-NEEEIRVQEMKKQS 256
+ E + WR+ EE+ K + W++ + ++K +++E +++E +++
Sbjct: 454 EQE-EMWRQEEKIREQEEIWRQKEKMHEQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKM 512
Query: 257 TKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEIS 316
+ E E ++KI +E I+ + K+ + ++EKI + K ++ +M E+ ++
Sbjct: 513 WRQEEKIREQEEKIREQEEKIREQKEKIRE---QEEKIWEQEEKIREQEEMMQEQEEKMW 569
Query: 317 ELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQK 369
E E ++ E++E +QE + EK + E E+ E + RQ+EE Q+
Sbjct: 570 E--QEEKMCEQEEKMQEQE----EKMRRQE----EKMWEQEVRLRQQEEKMQE 612
Score = 47.6 bits (108), Expect = 4e-04
Identities = 64/248 (25%), Positives = 110/248 (44%), Gaps = 31/248 (12%)
Query: 153 VETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSWRKPRLEES 212
+E +W K + I E ++ + K + E + + E K WR+ EE
Sbjct: 362 LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ---EEK 418
Query: 213 LEEVGPTKGVNEPEVCHWRKP-KTSEILKDKNEEEIRVQE-MKKQSTKALEVKDESKQKI 270
+ E + + E E WR+ K E K + EE+ + QE M +Q K E ++ +QK
Sbjct: 419 IRE--QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 476
Query: 271 PW-TQEAIKLRPTKV----EKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQN----- 320
QE I + KV EK ++EKI + K R++ + E+ +I E +
Sbjct: 477 KMHEQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 536
Query: 321 -------ERQITEKKESL--QETQLQPTEKN--KLLENIVSEESK---ESTGKRRQREEI 366
E +I E++E + QE +Q E+ + E + +E K + RRQ E++
Sbjct: 537 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 596
Query: 367 TQKEVALK 374
++EV L+
Sbjct: 597 WEQEVRLR 604
>AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein.
Length = 285
Score = 53.2 bits (122), Expect = 9e-06
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 8/148 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
NI + G C+A AGS+ V + D P++L P T +DG + L
Sbjct: 58 NIQRSDAGYYICQALTVAGSILAKAQLEVTD-VLTDRPPPIILQGPANQTLAVDGTAL-L 115
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
CK G P P I W E RD + Q+ G + IK G Y C A++
Sbjct: 116 KCKATGDPLPVISWL-KEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSS 172
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSD 1389
G+ S +L++ E ++S+ LSD
Sbjct: 173 GEASWSAVLDVT--ESGATISKNYDLSD 198
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 52.8 bits (121), Expect = 1e-05
Identities = 37/144 (25%), Positives = 58/144 (40%), Gaps = 10/144 (6%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLE--NTTVMDGERIS 1300
NI+K G+ C G V G + I P + P + N T GE ++
Sbjct: 175 NINKSDEGIYRCE-----GRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMT 229
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
+C+ G P P I WF N KLIE + K E+ ++ G Y C A+N+
Sbjct: 230 FSCRASGSPEPAISWFRNGKLIEENEKYIL---KGSNTELTVRNIINSDGGPYVCRATNK 286
Query: 1361 FGKCSTECILNIEAYEYVPSVSEE 1384
G+ + L + ++ + E
Sbjct: 287 AGEDEKQAFLQVFVQPHIIQLKNE 310
Score = 51.6 bits (118), Expect = 3e-05
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E +TF SG+P P I W+++ K+I +E++I+ K + T T++ G Y C+A
Sbjct: 226 EEMTFSCRASGSPEPAISWFRNGKLIEENEKYIL--KGSNTELTVRNIINSDGGPYVCRA 283
Query: 1598 VSDIGLAVTKAKLQVF 1613
+ G +A LQVF
Sbjct: 284 TNKAGEDEKQAFLQVF 299
Score = 40.3 bits (90), Expect = 0.066
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFH--NEKLIETARDITISRQKSGL-CEI 1340
V L + GE C +G P IDW++ EK+I T R + QK G+ +
Sbjct: 23 VTISLSKVELSVGESKFFTCTAIGEP-RSIDWYNPQGEKIISTQRVVV---QKGGVRSRL 78
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
I A E AGIY+C A++ G+ + E + +E Y+
Sbjct: 79 TIYNANIEDAGIYRCQATDAKGQ-TQEATVVLEIYQ 113
Score = 35.9 bits (79), Expect = 1.4
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
T G+ + +A G P+P + W R G +L++ E I L + LT+ + D G
Sbjct: 221 TAERGEEMTFSCRASGSPEPAISWFRNG-KLIEENEKYI--LKGSNTELTVRNIINSDGG 277
Query: 1471 EIVFEAYNHLGVTATIAALSV 1491
V A N G A L V
Sbjct: 278 PYVCRATNKAGEDEKQAFLQV 298
Score = 35.1 bits (77), Expect = 2.5
Identities = 42/167 (25%), Positives = 67/167 (40%), Gaps = 27/167 (16%)
Query: 1213 EKDSHIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVE 1272
E + +I++ +TELT R NI G CRA N AG E
Sbjct: 253 ENEKYILKGSNTELTVR-------------NIINSDGGPYVCRATNKAGED--------E 291
Query: 1273 EQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITIS 1331
+Q + + L+N T + +++L C G P P+I W + T D +
Sbjct: 292 KQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPD 351
Query: 1332 -----RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ + G +HIK+ +G Y C A+++ G L+IE
Sbjct: 352 GRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIGGHQKSMYLDIE 398
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 52.8 bits (121), Expect = 1e-05
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 8/148 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
NI + G C+A AGS+ V + D P++L P T +DG + L
Sbjct: 380 NIQRSDAGYYICQALTVAGSILAKAQLEVTD-VLTDRPPPIILQGPANQTLAVDGTAL-L 437
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
CK G P P I W E RD + Q+ G + IK G Y C A++
Sbjct: 438 KCKATGDPLPVISWL-KEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSS 494
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSD 1389
G+ S +L++ E ++S+ LSD
Sbjct: 495 GETSWSAVLDVT--ESGATISKNYDLSD 520
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PTF++ I + V EEE V F G+P P + W KD+ + R+ I++ T I
Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD---YTLRI 280
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
KK EGTY C A + +G A L V
Sbjct: 281 KKTMSTDEGTYMCIAENRVGKMEASATLTV 310
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ---KSG-- 1336
P ++ + V GE +LNCK GRP P I+W+ + + +ET +D S + SG
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90
Query: 1337 --LCEIHIKEAFPEMAGIYKCTASNQFGK 1363
L +H + + P+ G Y C A N G+
Sbjct: 91 FFLRIVHGRRSKPD-EGSYVCVARNYLGE 118
Score = 43.2 bits (97), Expect = 0.009
Identities = 84/376 (22%), Positives = 128/376 (34%), Gaps = 68/376 (18%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N K G+ TC N G + + E T + P L N V++ E +
Sbjct: 192 NTRKSDAGMYTCVGTNMVGERDSDPA----ELTVFE--RPTFLRRPINQVVLEEEAVEFR 245
Query: 1303 CKILGRPWPKIDWFHNEKLIETAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C++ G P P + W ++ + R DI + IK+ G Y C A N+
Sbjct: 246 CQVQGDPQPTVRWKKDDADLPRGRYDIKDD------YTLRIKKTMSTDEGTYMCIAENRV 299
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
GK L + A P+ V P +G+ +
Sbjct: 300 GKMEASATLTVRA------------------------PPQFV-VRPRDQIVAQGRTVTFP 334
Query: 1422 AKAIGIPKPQVRWLRQGTELL----QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
+ G P+P V W ++G++ L Q + T LT+ + + D G + +A
Sbjct: 335 CETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 394
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
G A L V ++ R P + LQ T +V +
Sbjct: 395 TVAGSILAKAQLEVTDVLTD---RPPPII-----LQGPANQTLAV--------------D 432
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
+ +G+P P I W K+ D R I + + T IK GTYTC
Sbjct: 433 GTALLKCKATGDPLPVISWLKEGFTFPGRDPRATI---QEQGTLQIKNLRISDTGTYTCV 489
Query: 1597 AVSDIGLAVTKAKLQV 1612
A S G A L V
Sbjct: 490 ATSSSGETSWSAVLDV 505
Score = 36.7 bits (81), Expect = 0.81
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE------RFIIENKENRTTCTIK-KAT 1586
V + E T G PTP I WYKD + + TD+ R ++ + + + +
Sbjct: 42 VSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 101
Query: 1587 KDLEGTYTCKAVSDIGLAVTK-AKLQV 1612
K EG+Y C A + +G AV++ A L+V
Sbjct: 102 KPDEGSYVCVARNYLGEAVSRNASLEV 128
Score = 35.5 bits (78), Expect = 1.9
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
E+F PRIV+ P+ V ++G+ L KA G P P + W + G
Sbjct: 27 EDFPPRIVEH-PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDG 68
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 52.8 bits (121), Expect = 1e-05
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 8/148 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
NI + G C+A AGS+ V + D P++L P T +DG + L
Sbjct: 396 NIQRSDAGYYICQALTVAGSILAKAQLEVTD-VLTDRPPPIILQGPANQTLAVDGTAL-L 453
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
CK G P P I W E RD + Q+ G + IK G Y C A++
Sbjct: 454 KCKATGDPLPVISWL-KEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSS 510
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSD 1389
G+ S +L++ E ++S+ LSD
Sbjct: 511 GETSWSAVLDVT--ESGATISKNYDLSD 536
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PTF++ I + V EEE V F G+P P + W KD+ + R+ I++ T I
Sbjct: 241 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD---YTLRI 296
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
KK EGTY C A + +G A L V
Sbjct: 297 KKTMSTDEGTYMCIAENRVGKMEASATLTV 326
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ---KSG-- 1336
P ++ + V GE +LNCK GRP P I+W+ + + +ET +D S + SG
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106
Query: 1337 --LCEIHIKEAFPEMAGIYKCTASNQFGK 1363
L +H + + P+ G Y C A N G+
Sbjct: 107 FFLRIVHGRRSKPD-EGSYVCVARNYLGE 134
Score = 43.2 bits (97), Expect = 0.009
Identities = 84/376 (22%), Positives = 128/376 (34%), Gaps = 68/376 (18%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N K G+ TC N G + + E T + P L N V++ E +
Sbjct: 208 NTRKSDAGMYTCVGTNMVGERDSDPA----ELTVFE--RPTFLRRPINQVVLEEEAVEFR 261
Query: 1303 CKILGRPWPKIDWFHNEKLIETAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C++ G P P + W ++ + R DI + IK+ G Y C A N+
Sbjct: 262 CQVQGDPQPTVRWKKDDADLPRGRYDIKDD------YTLRIKKTMSTDEGTYMCIAENRV 315
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
GK L + A P+ V P +G+ +
Sbjct: 316 GKMEASATLTVRA------------------------PPQFV-VRPRDQIVAQGRTVTFP 350
Query: 1422 AKAIGIPKPQVRWLRQGTELL----QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
+ G P+P V W ++G++ L Q + T LT+ + + D G + +A
Sbjct: 351 CETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 410
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
G A L V ++ R P + LQ T +V +
Sbjct: 411 TVAGSILAKAQLEVTDVLTD---RPPPII-----LQGPANQTLAV--------------D 448
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
+ +G+P P I W K+ D R I + + T IK GTYTC
Sbjct: 449 GTALLKCKATGDPLPVISWLKEGFTFPGRDPRATI---QEQGTLQIKNLRISDTGTYTCV 505
Query: 1597 AVSDIGLAVTKAKLQV 1612
A S G A L V
Sbjct: 506 ATSSSGETSWSAVLDV 521
Score = 36.7 bits (81), Expect = 0.81
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE------RFIIENKENRTTCTIK-KAT 1586
V + E T G PTP I WYKD + + TD+ R ++ + + + +
Sbjct: 58 VSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 117
Query: 1587 KDLEGTYTCKAVSDIGLAVTK-AKLQV 1612
K EG+Y C A + +G AV++ A L+V
Sbjct: 118 KPDEGSYVCVARNYLGEAVSRNASLEV 144
Score = 35.5 bits (78), Expect = 1.9
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
E+F PRIV+ P+ V ++G+ L KA G P P + W + G
Sbjct: 43 EDFPPRIVEH-PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDG 84
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 52.8 bits (121), Expect = 1e-05
Identities = 37/144 (25%), Positives = 58/144 (40%), Gaps = 10/144 (6%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLE--NTTVMDGERIS 1300
NI+K G+ C G V G + I P + P + N T GE ++
Sbjct: 175 NINKSDEGIYRCE-----GRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMT 229
Query: 1301 LNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQ 1360
+C+ G P P I WF N KLIE + K E+ ++ G Y C A+N+
Sbjct: 230 FSCRASGSPEPAISWFRNGKLIEENEKYIL---KGSNTELTVRNIINSDGGPYVCRATNK 286
Query: 1361 FGKCSTECILNIEAYEYVPSVSEE 1384
G+ + L + ++ + E
Sbjct: 287 AGEDEKQAFLQVFVQPHIIQLKNE 310
Score = 51.6 bits (118), Expect = 3e-05
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
E +TF SG+P P I W+++ K+I +E++I+ K + T T++ G Y C+A
Sbjct: 226 EEMTFSCRASGSPEPAISWFRNGKLIEENEKYIL--KGSNTELTVRNIINSDGGPYVCRA 283
Query: 1598 VSDIGLAVTKAKLQVF 1613
+ G +A LQVF
Sbjct: 284 TNKAGEDEKQAFLQVF 299
Score = 40.7 bits (91), Expect = 0.050
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 8/96 (8%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFH--NEKLIETARDITISRQKSGL-CEI 1340
V L + GE C +G P IDW++ EK+I T R + QK G+ +
Sbjct: 23 VTISLSKVELSVGESKFFTCTAIGEP-ESIDWYNPQGEKIISTQRVVV---QKEGVRSRL 78
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
I A E AGIY+C A++ G+ + E + +E Y+
Sbjct: 79 TIYNANIEDAGIYRCQATDAKGQ-TQEATVVLEIYQ 113
Score = 37.1 bits (82), Expect = 0.61
Identities = 42/167 (25%), Positives = 68/167 (40%), Gaps = 27/167 (16%)
Query: 1213 EKDSHIIEKDSTELTPRIIQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVE 1272
E + +I++ +TELT R NI G CRA N AG E
Sbjct: 253 ENEKYILKGSNTELTVR-------------NIINSDGGPYVCRATNKAGED--------E 291
Query: 1273 EQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHN-EKLIETARDITIS 1331
+Q + + L+N T + +++L C G P P+I W + T D ++
Sbjct: 292 KQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLD 351
Query: 1332 -----RQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIE 1373
+ + G +HIK+ +G Y C A+++ G L+IE
Sbjct: 352 GRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIE 398
Score = 35.9 bits (79), Expect = 1.4
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 1411 TTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTG 1470
T G+ + +A G P+P + W R G +L++ E I L + LT+ + D G
Sbjct: 221 TAERGEEMTFSCRASGSPEPAISWFRNG-KLIEENEKYI--LKGSNTELTVRNIINSDGG 277
Query: 1471 EIVFEAYNHLGVTATIAALSV 1491
V A N G A L V
Sbjct: 278 PYVCRATNKAGEDEKQAFLQV 298
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens cDNA
FLJ90299 fis, clone NT2RP2000514, highly similar to Homo
sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 52.8 bits (121), Expect = 1e-05
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 8/148 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
NI + G C+A AGS+ V + D P++L P T +DG + L
Sbjct: 101 NIQRSDAGYYICQALTVAGSILAKAQLEVTD-VLTDRPPPIILQGPANQTLAVDGTAL-L 158
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
CK G P P I W E RD + Q+ G + IK G Y C A++
Sbjct: 159 KCKATGDPLPVISWL-KEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSS 215
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSD 1389
G+ S +L++ E ++S+ LSD
Sbjct: 216 GETSWSAVLDVT--ESGATISKNYDLSD 241
Score = 34.7 bits (76), Expect = 3.3
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKD--------NKVIRTDERFIIENK 1574
P FV + V + VTF GNP P + W K+ N+ + + R +
Sbjct: 35 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 94
Query: 1575 ENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ T I+++ G Y C+A++ G + KA+L+V
Sbjct: 95 GDLTITNIQRSD---AGYYICQALTVAGSILAKAQLEV 129
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 52.8 bits (121), Expect = 1e-05
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 8/148 (5%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
NI + G C+A AGS+ V + D P++L P T +DG + L
Sbjct: 382 NIQRSDAGYYICQALTVAGSILAKAQLEVTD-VLTDRPPPIILQGPANQTLAVDGTAL-L 439
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
CK G P P I W E RD + Q+ G + IK G Y C A++
Sbjct: 440 KCKATGDPLPVISWL-KEGFTFPGRDPRATIQEQG--TLQIKNLRISDTGTYTCVATSSS 496
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSD 1389
G+ S +L++ E ++S+ LSD
Sbjct: 497 GETSWSAVLDVT--ESGATISKNYDLSD 522
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
PTF++ I + V EEE V F G+P P + W KD+ + R+ I++ T I
Sbjct: 227 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIKDD---YTLRI 282
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
KK EGTY C A + +G A L V
Sbjct: 283 KKTMSTDEGTYMCIAENRVGKMEASATLTV 312
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ---KSG-- 1336
P ++ + V GE +LNCK GRP P I+W+ + + +ET +D S + SG
Sbjct: 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 92
Query: 1337 --LCEIHIKEAFPEMAGIYKCTASNQFGK 1363
L +H + + P+ G Y C A N G+
Sbjct: 93 FFLRIVHGRRSKPD-EGSYVCVARNYLGE 120
Score = 43.2 bits (97), Expect = 0.009
Identities = 84/376 (22%), Positives = 128/376 (34%), Gaps = 68/376 (18%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLN 1302
N K G+ TC N G + + E T + P L N V++ E +
Sbjct: 194 NTRKSDAGMYTCVGTNMVGERDSDPA----ELTVFE--RPTFLRRPINQVVLEEEAVEFR 247
Query: 1303 CKILGRPWPKIDWFHNEKLIETAR-DITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
C++ G P P + W ++ + R DI + IK+ G Y C A N+
Sbjct: 248 CQVQGDPQPTVRWKKDDADLPRGRYDIKDD------YTLRIKKTMSTDEGTYMCIAENRV 301
Query: 1362 GKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLE 1421
GK L + A P+ V P +G+ +
Sbjct: 302 GKMEASATLTVRA------------------------PPQFV-VRPRDQIVAQGRTVTFP 336
Query: 1422 AKAIGIPKPQVRWLRQGTELL----QSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
+ G P+P V W ++G++ L Q + T LT+ + + D G + +A
Sbjct: 337 CETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 396
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEE 1537
G A L V ++ R P + LQ T +V +
Sbjct: 397 TVAGSILAKAQLEVTDVLTD---RPPPII-----LQGPANQTLAV--------------D 434
Query: 1538 EIVTFEAIYSGNPTPEILWYKDNKVI-RTDERFIIENKENRTTCTIKKATKDLEGTYTCK 1596
+ +G+P P I W K+ D R I + + T IK GTYTC
Sbjct: 435 GTALLKCKATGDPLPVISWLKEGFTFPGRDPRATI---QEQGTLQIKNLRISDTGTYTCV 491
Query: 1597 AVSDIGLAVTKAKLQV 1612
A S G A L V
Sbjct: 492 ATSSSGETSWSAVLDV 507
Score = 36.7 bits (81), Expect = 0.81
Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 1534 VHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDE------RFIIENKENRTTCTIK-KAT 1586
V + E T G PTP I WYKD + + TD+ R ++ + + + +
Sbjct: 44 VSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRS 103
Query: 1587 KDLEGTYTCKAVSDIGLAVTK-AKLQV 1612
K EG+Y C A + +G AV++ A L+V
Sbjct: 104 KPDEGSYVCVARNYLGEAVSRNASLEV 130
Score = 35.5 bits (78), Expect = 1.9
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
E+F PRIV+ P+ V ++G+ L KA G P P + W + G
Sbjct: 29 EDFPPRIVEH-PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDG 70
>U18985-1|AAA75315.1| 729|Homo sapiens triadin protein.
Length = 729
Score = 52.4 bits (120), Expect = 2e-05
Identities = 72/284 (25%), Positives = 120/284 (42%), Gaps = 33/284 (11%)
Query: 234 KTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEK-E 292
+ EI KDK E++ + E K Q+ + K++ K+K+ +E K K IEK E
Sbjct: 139 RKKEIHKDKTEKQEK-PERKIQTKVTHKEKEKGKEKV---REKEKPEKKATHKEKIEKKE 194
Query: 293 KIEDVALKPVRKDSLMDEKSSEISELQNE-------RQITEKKESLQETQLQPTEKNKLL 345
K E + +K + EKS E ++ + + +Q K + +Q+T +P EK
Sbjct: 195 KPETKTVAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEK---- 250
Query: 346 ENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKET 405
++ K + K Q++ Q + ++ P L TE+ S+ T
Sbjct: 251 ----EDKEKAAVSKHEQKD---QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPT 303
Query: 406 --EDRINTK--DTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEIT 461
+ K + +K T E K ++K EKE D+ K K S + T
Sbjct: 304 PASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKS-EKETAIDVEKKEPGKASETKQGT 362
Query: 462 EEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEE 505
++ A +A D +KE+ K K P E + P GK+Q K+E
Sbjct: 363 VKIAAQAAAKKDEKKEDSKKTK-----KPAEVEQPKGKKQEKKE 401
Score = 45.2 bits (102), Expect = 0.002
Identities = 107/470 (22%), Positives = 175/470 (37%), Gaps = 48/470 (10%)
Query: 148 KVQEVVETKLWRKPKTISEKKDLLQVSTHEDTN----------ILKVENLESVNVDTTSS 197
KV+EV +T KPK E K+ VS HE + I +L+
Sbjct: 236 KVKEVQKTP--SKPKE-KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292
Query: 198 KLETKSWRKPR-LEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQS 256
L T+ +P +LEE K E +V K K E +K K+E+E + KK+
Sbjct: 293 PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEP 352
Query: 257 TKALEV--------------KDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPV 302
KA E KDE K+ T++ ++ K +K +KEK + A P
Sbjct: 353 GKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQE-KKEKHVEPAKSPK 411
Query: 303 RKDSLMDEK--SSEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKR 360
++ S+ +K ++ + E K+++ + + T K + + I E+S +++
Sbjct: 412 KEHSVPSDKQVKAKTERAKEEIGAVSSKKAVPGKKEEKTTKT-VEQEIRKEKSGKTSSIL 470
Query: 361 RQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIP 420
+ +E I KE + S KE K ++ K KP
Sbjct: 471 KDKEPIKGKEEKVPASLKEKEPETKKDEKMS-----KAGKEVKPKPPQLQGKKEEKPEPQ 525
Query: 421 WTQEAIKLRPTKMEKTPIEKEKFEDITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHK 480
+EA +P EK I K +DI +KP + S + E+V A+ + + K
Sbjct: 526 IKKEA---KPAISEKVQIHK---QDI-VKPEKTVS-HGKPEEKVLKQVKAVTIEKTAKPK 577
Query: 481 PDKVSENNAPEERKWPTGKRQPKEETPQEEVVLKPTRXXXXXXXXXXXXXXWPSGKRRPK 540
P K +E+ E T K +P + E V + + R K
Sbjct: 578 PTKKAEHREREPPSIKTDKPKPTPKGTSE--VTESGKKKTEISEKESKEKADMKHLREEK 635
Query: 541 EETPQEEVVLXXXXXXXXXXXXXXXXXXXXXVKKEKQ-IEDATPEERKWP 589
T +E + L KK K+ ED +P ++K P
Sbjct: 636 VSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQKSP 685
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 52.4 bits (120), Expect = 2e-05
Identities = 71/317 (22%), Positives = 123/317 (38%), Gaps = 44/317 (13%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITIS-RQKSGLCEIHIKEAF--PEMAGIY 1353
+ I + C+ G P P W N + A+D +S R++SG I + E G Y
Sbjct: 27 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 86
Query: 1354 KCTASNQFGKC-STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
+C A N+FG S L + P + + V+ V+E AP ++ P
Sbjct: 87 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV-------VQEGAPLTLQCNPPP--- 136
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
G+P P + W+ E + + + ++ + +G + + QD +
Sbjct: 137 -------------GLPSPVIFWMSSSMEPI-TQDKRVSQGHNG-DLYFSNVMLQDMQTDY 181
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A H T ++ Y H ++ +A + P+F + P+
Sbjct: 182 SCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNH-PDMYSARGVAERTPSF---MYPQ 237
Query: 1533 RVHEEEIV------TFEAIYSGNPTPEILWYKDNKVIRTDE-RFIIENKENRTTCTIKKA 1585
++V E I SG PTP+I WYK + +D+ +F NK R T
Sbjct: 238 GTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRIT----NV 293
Query: 1586 TKDLEGTYTCKAVSDIG 1602
+++ G Y C A + +G
Sbjct: 294 SEEDSGEYFCLASNKMG 310
Score = 43.6 bits (98), Expect = 0.007
Identities = 69/271 (25%), Positives = 109/271 (40%), Gaps = 41/271 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
KAL + N+S++ G C A N GS+ + S V+ AP L +N +
Sbjct: 286 KALRIT--NVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILA 336
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE L C+ G P P + W N + +++A +R+ +G I ++ +Y+
Sbjct: 337 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAG-DTIIFRDTQISSRAVYQ 394
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C SN+ G L A+ VS DV PR++ ++
Sbjct: 395 CNTSNEHG------YLLANAF-----VSVLDV------------PPRMLSPRNQLIRVIL 431
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
RL+ G P P +RW + G L Y + E +G+ L + + ++D G
Sbjct: 432 YNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE--NGS--LEIKMIRKEDQGIYT 487
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
A N LG L V+ T+ YR PE
Sbjct: 488 CVATNILGKAENQVRLEVKD--PTRIYRMPE 516
Score = 35.5 bits (78), Expect = 1.9
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 4/116 (3%)
Query: 1282 PLVLAPLENTT-VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P +L+P V+ R L+C G P P + WF N + ++G EI
Sbjct: 417 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG-NYHVYENGSLEI 475
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
K E GIY C A+N GK + L ++ + + E+ V T +E
Sbjct: 476 --KMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLE 529
Score = 34.7 bits (76), Expect = 3.3
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 1546 YSGNPTPEILWYKDNKVIRTD--ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGL 1603
+ G+P P + W+K+ + D + EN + IK K+ +G YTC A + +G
Sbjct: 441 FFGSPIPTLRWFKNGQGSNLDGGNYHVYENG----SLEIKMIRKEDQGIYTCVATNILGK 496
Query: 1604 AVTKAKLQV 1612
A + +L+V
Sbjct: 497 AENQVRLEV 505
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 52.4 bits (120), Expect = 2e-05
Identities = 71/317 (22%), Positives = 123/317 (38%), Gaps = 44/317 (13%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITIS-RQKSGLCEIHIKEAF--PEMAGIY 1353
+ I + C+ G P P W N + A+D +S R++SG I + E G Y
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 1354 KCTASNQFGKC-STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
+C A N+FG S L + P + + V+ V+E AP ++ P
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV-------VQEGAPLTLQCNPPP--- 160
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
G+P P + W+ E + + + ++ + +G + + QD +
Sbjct: 161 -------------GLPSPVIFWMSSSMEPI-TQDKRVSQGHNG-DLYFSNVMLQDMQTDY 205
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A H T ++ Y H ++ +A + P+F + P+
Sbjct: 206 SCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNH-PDMYSARGVAERTPSF---MYPQ 261
Query: 1533 RVHEEEIV------TFEAIYSGNPTPEILWYKDNKVIRTDE-RFIIENKENRTTCTIKKA 1585
++V E I SG PTP+I WYK + +D+ +F NK R T
Sbjct: 262 GTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRIT----NV 317
Query: 1586 TKDLEGTYTCKAVSDIG 1602
+++ G Y C A + +G
Sbjct: 318 SEEDSGEYFCLASNKMG 334
Score = 43.6 bits (98), Expect = 0.007
Identities = 69/271 (25%), Positives = 109/271 (40%), Gaps = 41/271 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
KAL + N+S++ G C A N GS+ + S V+ AP L +N +
Sbjct: 310 KALRIT--NVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILA 360
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE L C+ G P P + W N + +++A +R+ +G I ++ +Y+
Sbjct: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAG-DTIIFRDTQISSRAVYQ 418
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C SN+ G L A+ VS DV PR++ ++
Sbjct: 419 CNTSNEHG------YLLANAF-----VSVLDV------------PPRMLSPRNQLIRVIL 455
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
RL+ G P P +RW + G L Y + E +G+ L + + ++D G
Sbjct: 456 YNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE--NGS--LEIKMIRKEDQGIYT 511
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
A N LG L V+ T+ YR PE
Sbjct: 512 CVATNILGKAENQVRLEVKD--PTRIYRMPE 540
Score = 35.5 bits (78), Expect = 1.9
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 4/116 (3%)
Query: 1282 PLVLAPLENTT-VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P +L+P V+ R L+C G P P + WF N + ++G EI
Sbjct: 441 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG-NYHVYENGSLEI 499
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
K E GIY C A+N GK + L ++ + + E+ V T +E
Sbjct: 500 --KMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLE 553
Score = 34.7 bits (76), Expect = 3.3
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 1546 YSGNPTPEILWYKDNKVIRTD--ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGL 1603
+ G+P P + W+K+ + D + EN + IK K+ +G YTC A + +G
Sbjct: 465 FFGSPIPTLRWFKNGQGSNLDGGNYHVYENG----SLEIKMIRKEDQGIYTCVATNILGK 520
Query: 1604 AVTKAKLQV 1612
A + +L+V
Sbjct: 521 AENQVRLEV 529
>AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 variant
protein.
Length = 1130
Score = 52.4 bits (120), Expect = 2e-05
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 1511 ELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFI 1570
E QA L Q+ P F+K+ HE + FE +G PTP + W K+ ++ + F
Sbjct: 6 EAQAEL-TVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFK 64
Query: 1571 IENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
I + N + K+ EG Y C A +D+G A A+L + +
Sbjct: 65 IVKEHNLQVLGLVKSD---EGFYQCIAENDVGNAQAGAQLIILE 105
Score = 33.5 bits (73), Expect = 7.6
Identities = 30/154 (19%), Positives = 57/154 (37%), Gaps = 10/154 (6%)
Query: 1267 GSSIVEEQTCIDGDA-PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA 1325
G+ +E Q + A P L N + I C++ G+P P + W N ++ +
Sbjct: 1 GNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPS 60
Query: 1326 RDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEY-VPSVSEE 1384
I ++ + + + G Y+C A N G L I ++ +P++
Sbjct: 61 DYFKIVKEHN----LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPT 116
Query: 1385 DVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLI 1418
+ S + + AP LP+ L+
Sbjct: 117 SLTS----ATTDHLAPATTGPLPSAPRDVVASLV 146
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 52.4 bits (120), Expect = 2e-05
Identities = 71/317 (22%), Positives = 123/317 (38%), Gaps = 44/317 (13%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITIS-RQKSGLCEIHIKEAF--PEMAGIY 1353
+ I + C+ G P P W N + A+D +S R++SG I + E G Y
Sbjct: 104 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 163
Query: 1354 KCTASNQFGKC-STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTT 1412
+C A N+FG S L + P + + V+ V+E AP ++ P
Sbjct: 164 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV-------VQEGAPLTLQCNPPP--- 213
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
G+P P + W+ E + + + ++ + +G + + QD +
Sbjct: 214 -------------GLPSPVIFWMSSSMEPI-TQDKRVSQGHNG-DLYFSNVMLQDMQTDY 258
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE 1532
A H T ++ Y H ++ +A + P+F + P+
Sbjct: 259 SCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNH-PDMYSARGVAERTPSF---MYPQ 314
Query: 1533 RVHEEEIV------TFEAIYSGNPTPEILWYKDNKVIRTDE-RFIIENKENRTTCTIKKA 1585
++V E I SG PTP+I WYK + +D+ +F NK R T
Sbjct: 315 GTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRIT----NV 370
Query: 1586 TKDLEGTYTCKAVSDIG 1602
+++ G Y C A + +G
Sbjct: 371 SEEDSGEYFCLASNKMG 387
Score = 43.6 bits (98), Expect = 0.007
Identities = 69/271 (25%), Positives = 109/271 (40%), Gaps = 41/271 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
KAL + N+S++ G C A N GS+ + S V+ AP L +N +
Sbjct: 363 KALRIT--NVSEEDSGEYFCLASNKMGSIRHTISVRVKA-------APYWLDEPKNLILA 413
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE L C+ G P P + W N + +++A +R+ +G I ++ +Y+
Sbjct: 414 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAG-DTIIFRDTQISSRAVYQ 471
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C SN+ G L A+ VS DV PR++ ++
Sbjct: 472 CNTSNEHG------YLLANAF-----VSVLDV------------PPRMLSPRNQLIRVIL 508
Query: 1415 GKLIRLEAKAIGIPKPQVRWLRQGT-ELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
RL+ G P P +RW + G L Y + E +G+ L + + ++D G
Sbjct: 509 YNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE--NGS--LEIKMIRKEDQGIYT 564
Query: 1474 FEAYNHLGVTATIAALSVESIVGTQEYRKPE 1504
A N LG L V+ T+ YR PE
Sbjct: 565 CVATNILGKAENQVRLEVKD--PTRIYRMPE 593
Score = 35.5 bits (78), Expect = 1.9
Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 4/116 (3%)
Query: 1282 PLVLAPLENTT-VMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEI 1340
P +L+P V+ R L+C G P P + WF N + ++G EI
Sbjct: 494 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG-NYHVYENGSLEI 552
Query: 1341 HIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVE 1396
K E GIY C A+N GK + L ++ + + E+ V T +E
Sbjct: 553 --KMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLE 606
Score = 34.7 bits (76), Expect = 3.3
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 1546 YSGNPTPEILWYKDNKVIRTD--ERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGL 1603
+ G+P P + W+K+ + D + EN + IK K+ +G YTC A + +G
Sbjct: 518 FFGSPIPTLRWFKNGQGSNLDGGNYHVYENG----SLEIKMIRKEDQGIYTCVATNILGK 573
Query: 1604 AVTKAKLQV 1612
A + +L+V
Sbjct: 574 AENQVRLEV 582
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 52.0 bits (119), Expect = 2e-05
Identities = 74/316 (23%), Positives = 126/316 (39%), Gaps = 40/316 (12%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQK-SGLCEIHI-KEAFPEM-AGIY 1353
E I + C+ G+P P W N + +D ++ + +G I+I E E G+Y
Sbjct: 57 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 116
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+CTA N+ G +VS V+ ++ P K +T
Sbjct: 117 QCTARNERGA----------------AVSNNIVVRPSRS-------PLWTKEKLEPITLQ 153
Query: 1414 EGKLIRLEAKA-IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGE- 1471
G+ + L + IG+P P + W+ + L +E + L+ L V +DT E
Sbjct: 154 SGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD---LYFSNVLPEDTRED 210
Query: 1472 -IVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHME-ELQAALKATQSVPTFVKEI 1529
I + +NH +SV+ ++ E + E A + + PTF+
Sbjct: 211 YICYARFNHTQTIQQKQPISVK-VISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPE 269
Query: 1530 IPERVHEE---EIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
EE +++ E I G PTP I W K++ ++ R + +N E T I +
Sbjct: 270 GNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEK--TLQIIHVS 326
Query: 1587 KDLEGTYTCKAVSDIG 1602
+ G Y C A + +G
Sbjct: 327 EADSGNYQCIAKNALG 342
Score = 48.4 bits (110), Expect = 2e-04
Identities = 66/268 (24%), Positives = 104/268 (38%), Gaps = 41/268 (15%)
Query: 1235 KALNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVM 1294
K L ++ ++S+ G C A+N G++ + S V+ AP + +N +
Sbjct: 318 KTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKA-------APYWITAPQNLVLS 368
Query: 1295 DGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYK 1354
GE +L C+ G P P+I W N IE A D SR+ G I + +Y+
Sbjct: 369 PGEDGTLICRANGNPKPRISWLTNGVPIEIAPD-DPSRKIDG-DTIIFSNVQERSSAVYQ 426
Query: 1355 CTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTE 1414
C ASN++G +N+ A PRI+ T+
Sbjct: 427 CNASNEYGYLLANAFVNVLAE-----------------------PPRILTPANTLYQVIA 463
Query: 1415 GKLIRLEAKAIGIPKPQVRWLR--QGTELLQST----EYQIEELDDGTSIL-TMPEVYQD 1467
+ L+ G P P + W + +G+ L + E E+ D T I+ +P +D
Sbjct: 464 NRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIKDATWIVKEIPVAQKD 523
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVESIV 1495
TG A N LG+ L E V
Sbjct: 524 STGTYTCVARNKLGMAKNEVHLQPEYAV 551
Score = 38.7 bits (86), Expect = 0.20
Identities = 75/325 (23%), Positives = 123/325 (37%), Gaps = 55/325 (16%)
Query: 1290 NTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEM 1349
N + G +SL C G P P I W + ++ R + + +K+ L IH+ EA
Sbjct: 274 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT-LQIIHVSEA---D 329
Query: 1350 AGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV 1409
+G Y+C A N G + ++A Y + + VLS +
Sbjct: 330 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGE------------------ 371
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+G LI +A G PKP++ WL G + + + ++D T I + +
Sbjct: 372 ----DGTLI---CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAV 424
Query: 1470 GEI-VFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPT--FV 1526
+ Y +L A + L+ + T + + + L +PT +
Sbjct: 425 YQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWF 484
Query: 1527 KEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKAT 1586
K +HE+ V E N T EI D +I++ I A
Sbjct: 485 KGAKGSALHEDIYVLHE-----NGTLEI----------KDATWIVKE--------IPVAQ 521
Query: 1587 KDLEGTYTCKAVSDIGLAVTKAKLQ 1611
KD GTYTC A + +G+A + LQ
Sbjct: 522 KDSTGTYTCVARNKLGMAKNEVHLQ 546
Score = 37.9 bits (84), Expect = 0.35
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 1534 VHEEEIVTFEAIYSGNPTPE--ILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEG 1591
V +V+FE + T +LW KDN+ + +DERF ++ + + + D G
Sbjct: 552 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD----KDHLVVADVSDDDSG 607
Query: 1592 TYTCKAVSDIGLAVTKAKLQV 1612
TYTC A + + A L V
Sbjct: 608 TYTCVANTTLDSVSASAVLSV 628
>BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,
165kDa protein.
Length = 1465
Score = 52.0 bits (119), Expect = 2e-05
Identities = 62/239 (25%), Positives = 101/239 (42%), Gaps = 12/239 (5%)
Query: 1384 EDVLSDEKTSDVEEF--APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
ED L+ E+ + E AP I+ L + T E ++L G P P V+W + G+ +
Sbjct: 136 EDKLAWERHTFEERISRAPEILVRLRSH-TVWERMSVKLCFTVQGFPTPVVQWYKDGSLI 194
Query: 1442 LQSTE---YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQ 1498
Q+ E Y+IE + G L + DDT A N G +T AA+ V G +
Sbjct: 195 CQAAEPGKYRIES-NYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDE 253
Query: 1499 EYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPT-----PE 1553
E + + L + + T F+++ E E VT + P P
Sbjct: 254 EPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPR 313
Query: 1554 ILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
WY+D+ +++ + + E + + + KD EG YT + VS G++ A L V
Sbjct: 314 AEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFV 372
Score = 50.0 bits (114), Expect = 8e-05
Identities = 21/92 (22%), Positives = 50/92 (54%), Gaps = 1/92 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T+M+G+ ++L C + G P P++ WF N++ I+ + ++ +++ + IK E +G
Sbjct: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414
Query: 1352 IYKCTASNQFGKCSTECILNIEAY-EYVPSVS 1382
Y N++G + +++ + E +P ++
Sbjct: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMA 1446
Score = 47.2 bits (107), Expect = 6e-04
Identities = 36/170 (21%), Positives = 72/170 (42%), Gaps = 5/170 (2%)
Query: 1312 KIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILN 1371
K++W H + I ++ + I + + + I E + G Y + GK + + L+
Sbjct: 1261 KVNWCHKDAKISSSEHMRIGGSEE-MAWLQICEPTEKDKGKYTFEIFD--GKDNHQRSLD 1317
Query: 1372 IEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQ 1431
+ + + +E + + E+ R++ LP VVT EGK + L G P P+
Sbjct: 1318 LSGQAFDEAFAEFQQF--KAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPE 1375
Query: 1432 VRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
V W + ++ S + ++ +T+ V +D+G+ N G
Sbjct: 1376 VIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425
Score = 45.2 bits (102), Expect = 0.002
Identities = 61/308 (19%), Positives = 129/308 (41%), Gaps = 32/308 (10%)
Query: 1299 ISLNCKILGRPWPKI-DWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L CK+ + W ++ L ET T+ + G+CE+ I + + G YK T
Sbjct: 1146 VRLVCKVANTKKETVFKWLKDDALYETE---TLPNLERGICELLIPKLSKKDHGEYKATL 1202
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
+ G+ ++ E V ++ +L+ + + +P V+ T EG
Sbjct: 1203 KDDRGQ-------DVSILEIAGKVYDDMILAMSRVCG-KSASPL------KVLCTPEGIR 1248
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
++ K + +V W + ++ S +I ++ + L + E + D G+ FE +
Sbjct: 1249 LQCFMKYF-TDEMKVNWCHKDAKISSSEHMRIGGSEE-MAWLQICEPTEKDKGKYTFEIF 1306
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE--RVH 1535
+ LS ++ E ++ +AA A ++ + + P+ +
Sbjct: 1307 DGKDNHQRSLDLSGQAF--------DEAFAEFQQFKAAAFAEKNRGRLIGGL-PDVVTIM 1357
Query: 1536 EEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR-TTCTIKKATKDLEGTYT 1594
E + + GNP PE++W+K+++ I+ E F ++ ++ + + TIK T + G Y+
Sbjct: 1358 EGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYS 1417
Query: 1595 CKAVSDIG 1602
+ G
Sbjct: 1418 INIKNKYG 1425
Score = 42.7 bits (96), Expect = 0.012
Identities = 50/222 (22%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKS--GLC 1338
AP +L L + TV + + L + G P P + W+ + LI A + R +S G+
Sbjct: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAY----EYVPSVSEEDVLSDEKTSD 1394
+ I A + Y A+N G+ ST + + + E SV L
Sbjct: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP-----KPQVRWLRQGTELLQSTEYQI 1449
F + ++ V EG+ + L+ + P +P+ W R LL+ +++
Sbjct: 273 YTHFDVQFLEKF-GVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDV-LLKESKWTK 330
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+G + L+ +++DD G + GV+ A L V
Sbjct: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFV 372
>X69089-1|CAA48832.1| 1465|Homo sapiens 165kD protein protein.
Length = 1465
Score = 51.6 bits (118), Expect = 3e-05
Identities = 62/239 (25%), Positives = 100/239 (41%), Gaps = 12/239 (5%)
Query: 1384 EDVLSDEKTSDVEEF--APRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTEL 1441
ED L+ E+ + E AP I+ L + T E ++L G P P V+W + G+ +
Sbjct: 136 EDKLAWERHTFEERISRAPEILVRLRSH-TVWERMSVKLCFTVQGFPTPVVQWYKDGSLI 194
Query: 1442 LQSTE---YQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQ 1498
Q+ E Y+IE + G L + DDT A N G +T AA+ V G +
Sbjct: 195 CQAAEPGKYRIES-NYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDE 253
Query: 1499 EYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPT-----PE 1553
E + + L + + T F+++ E E VT + P P
Sbjct: 254 EPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPR 313
Query: 1554 ILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
WY+D+ +++ + + E + + + KD EG YT + VS G+ A L V
Sbjct: 314 AEWYRDDLLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVTDHSAFLFV 372
Score = 50.0 bits (114), Expect = 8e-05
Identities = 21/92 (22%), Positives = 50/92 (54%), Gaps = 1/92 (1%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T+M+G+ ++L C + G P P++ WF N++ I+ + ++ +++ + IK E +G
Sbjct: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414
Query: 1352 IYKCTASNQFGKCSTECILNIEAY-EYVPSVS 1382
Y N++G + +++ + E +P ++
Sbjct: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEKIPDMA 1446
Score = 47.2 bits (107), Expect = 6e-04
Identities = 36/170 (21%), Positives = 72/170 (42%), Gaps = 5/170 (2%)
Query: 1312 KIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILN 1371
K++W H + I ++ + I + + + I E + G Y + GK + + L+
Sbjct: 1261 KVNWCHKDAKISSSEHMRIGGSEE-MAWLQICEPTEKDKGKYTFEIFD--GKDNHQRSLD 1317
Query: 1372 IEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQ 1431
+ + + +E + + E+ R++ LP VVT EGK + L G P P+
Sbjct: 1318 LSGQAFDEAFAEFQQF--KAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPE 1375
Query: 1432 VRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
V W + ++ S + ++ +T+ V +D+G+ N G
Sbjct: 1376 VIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYG 1425
Score = 45.2 bits (102), Expect = 0.002
Identities = 61/308 (19%), Positives = 129/308 (41%), Gaps = 32/308 (10%)
Query: 1299 ISLNCKILGRPWPKI-DWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTA 1357
+ L CK+ + W ++ L ET T+ + G+CE+ I + + G YK T
Sbjct: 1146 VRLVCKVANTKKETVFKWLKDDALYETE---TLPNLERGICELLIPKLSKKDHGEYKATL 1202
Query: 1358 SNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKL 1417
+ G+ ++ E V ++ +L+ + + +P V+ T EG
Sbjct: 1203 KDDRGQ-------DVSILEIAGKVYDDMILAMSRVCG-KSASPL------KVLCTPEGIR 1248
Query: 1418 IRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAY 1477
++ K + +V W + ++ S +I ++ + L + E + D G+ FE +
Sbjct: 1249 LQCFMKYF-TDEMKVNWCHKDAKISSSEHMRIGGSEE-MAWLQICEPTEKDKGKYTFEIF 1306
Query: 1478 NHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPE--RVH 1535
+ LS ++ E ++ +AA A ++ + + P+ +
Sbjct: 1307 DGKDNHQRSLDLSGQAF--------DEAFAEFQQFKAAAFAEKNRGRLIGGL-PDVVTIM 1357
Query: 1536 EEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR-TTCTIKKATKDLEGTYT 1594
E + + GNP PE++W+K+++ I+ E F ++ ++ + + TIK T + G Y+
Sbjct: 1358 EGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYS 1417
Query: 1595 CKAVSDIG 1602
+ G
Sbjct: 1418 INIKNKYG 1425
Score = 44.0 bits (99), Expect = 0.005
Identities = 51/222 (22%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKS--GLC 1338
AP +L L + TV + + L + G P P + W+ + LI A + R +S G+
Sbjct: 153 APEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVH 212
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAY----EYVPSVSEEDVLSDEKTSD 1394
+ I A + Y A+N G+ ST + + + E SV L
Sbjct: 213 TLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIP 272
Query: 1395 VEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP-----KPQVRWLRQGTELLQSTEYQI 1449
F + ++ V EG+ + L+ + P +P+ W R LL+ +++
Sbjct: 273 YTHFDVQFLEKF-GVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDL-LLKESKWTK 330
Query: 1450 EELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
+G + L+ +++DD G + GVT A L V
Sbjct: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVTDHSAFLFV 372
>U57099-1|AAC50599.1| 113|Homo sapiens APEG-1 protein protein.
Length = 113
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE-NR 1577
+++ PTF ++ + V E + V G P P + W ++ + +R D+R E E
Sbjct: 16 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGL 75
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A + G YTCKAV++ G +A+L+V
Sbjct: 76 CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L + +V +G+ + ++ ++ G P P + W N + + + + GLC +
Sbjct: 20 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 79
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I A AG Y C A N++G E L +
Sbjct: 80 ILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 37.5 bits (83), Expect = 0.47
Identities = 27/103 (26%), Positives = 40/103 (38%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+ ++SD AP K + EG+ + + + G PKP V WLR +
Sbjct: 8 NRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRF 67
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
EE + G L + + D G +A N G A L V
Sbjct: 68 AEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
>L06237-1|AAA18904.1| 2468|Homo sapiens microtubule-associated
protein 1B protein.
Length = 2468
Score = 51.6 bits (118), Expect = 3e-05
Identities = 65/273 (23%), Positives = 112/273 (41%), Gaps = 13/273 (4%)
Query: 235 TSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSP-IE-KE 292
T + + K ++ +E K + K L K K+ T E K+ VEK P +E KE
Sbjct: 527 TPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVN--HVEKPPKVESKE 584
Query: 293 KIEDVALKPVRKDSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEE 352
K+ KPV+ ++ E+ + + + Q T ++P E V +E
Sbjct: 585 KVMVKKDKPVKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAK---EKTVKKE 641
Query: 353 SKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTK 412
+K +++ +E +KEVA K + K V +KE K+ E + K
Sbjct: 642 TKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEV---KKEIKKEEKKEPKK 698
Query: 413 DTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDITLKP--TRKQSLVDEITEEVCALKSA 470
+ +K + P + + K E EKE ++I P +K S ++ ALK
Sbjct: 699 EVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPK 758
Query: 471 LDDIEKEEHKPDKVSENNAPEERKWPTGKRQPK 503
+ ++E K D V+ E+ K K++ K
Sbjct: 759 VPK-KEESVKKDSVAAGKPKEKGKIKVIKKEGK 790
Score = 43.2 bits (97), Expect = 0.009
Identities = 57/229 (24%), Positives = 92/229 (40%), Gaps = 16/229 (6%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
E + EV + KP + K+ +V +D + K E SV SK E
Sbjct: 560 ESKEETPEVTKVNHVEKPPKVESKE---KVMVKKDKPV-KTETKPSVTEKEVPSKEEPSP 615
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVK 263
+ E+ +V P K E V K +T +DK EE+ + ++ + +K
Sbjct: 616 VKAEVAEKQATDVKP-KAAKEKTV----KKETKVKPEDKKEEKEKPKKEVAKKEDKTPIK 670
Query: 264 DESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEK---SSEISELQN 320
E K K ++ +K K EK +KE ++ K V+K+ +EK E E +
Sbjct: 671 KEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKK 730
Query: 321 ERQITEKKESLQETQLQPTEKNKLLENIV--SEES--KESTGKRRQREE 365
E + K T L +K L+ V EES K+S + +E+
Sbjct: 731 EIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEK 779
Score = 39.9 bits (89), Expect = 0.087
Identities = 51/246 (20%), Positives = 99/246 (40%), Gaps = 22/246 (8%)
Query: 279 LRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISEL------------QNERQITE 326
++ TK+++ +E ++ A KP+ S+ E E E+ +++ ++
Sbjct: 530 VKQTKLKQRADSRESLKPAA-KPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMV 588
Query: 327 KKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXX 386
KK+ +T+ +P+ K + + ++ +Q ++ K KTV+
Sbjct: 589 KKDKPVKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPED 648
Query: 387 XXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEKFEDI 446
KP +KE + ED+ K KP ++ +K K EK +KE ++
Sbjct: 649 KKEEKEKP----KKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704
Query: 447 TLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAP-EERKWPTGKRQPKEE 505
K +K+ +E E K +I+K P +++ P E K P + PK
Sbjct: 705 PPKEVKKEVKKEEKKEVKKEEKEPKKEIKK---LPKDAKKSSTPLSEAKKPAALK-PKVP 760
Query: 506 TPQEEV 511
+E V
Sbjct: 761 KKEESV 766
Score = 37.9 bits (84), Expect = 0.35
Identities = 54/235 (22%), Positives = 96/235 (40%), Gaps = 18/235 (7%)
Query: 199 LETKSWRKPRLEESLE-------EVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQE 251
L +KS RK EE+ E E P E + KP +E E+E+ +E
Sbjct: 552 LPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPVKTETKPSVTEKEVPSKE 611
Query: 252 MKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEK---IEDVALK----PVRK 304
+ K + K +E + TKV+ ++EK ++VA K P++K
Sbjct: 612 EPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKK 671
Query: 305 DSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQRE 364
+ +K E++ E + EKKE +E + + T ++ + + EE KE K+ ++E
Sbjct: 672 EE-KPKKEEVKKEVKKEIKKEEKKEPKKEVK-KETPPKEVKKEVKKEEKKEV--KKEEKE 727
Query: 365 EITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSI 419
+ + K + +LKP + ++ES + + K K I
Sbjct: 728 PKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKI 782
Score = 35.5 bits (78), Expect = 1.9
Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Query: 392 LKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKL----RPTKME---KTPIEKEKFE 444
LK + + K + +K RK S T E K+ +P K+E K ++K+K
Sbjct: 535 LKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPV 594
Query: 445 DITLKPTRKQSLVDEITEEVCALKSALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKE 504
KP+ + V EE +K+ + + + + KP E +E K ++ ++
Sbjct: 595 KTETKPSVTEKEVPS-KEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEK 653
Query: 505 ETPQEEVVLK 514
E P++EV K
Sbjct: 654 EKPKKEVAKK 663
Score = 33.9 bits (74), Expect = 5.7
Identities = 62/312 (19%), Positives = 126/312 (40%), Gaps = 14/312 (4%)
Query: 145 EHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKSW 204
E +K +EV TK + + E ++ L+ + + +++ E + + + T +
Sbjct: 841 EELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTE 900
Query: 205 RKPRLEESLEEVGPTK--GVNEPEVCHWRKPKTSEILKDKN-EEEIRVQEMKKQSTKALE 261
+ E++ EE+ P + GV++ E E + + EE+ +E ++ E
Sbjct: 901 GEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEEDGEE 960
Query: 262 VKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDE--KSSEISELQ 319
S K T++ K E +EK E VA R + MDE + E + +
Sbjct: 961 HVCVSASKHSPTEDE---ESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSE 1017
Query: 320 NERQITEKKESLQETQLQPTEKNKLLENI--VSEESKESTGKRRQREEITQKEVALKTVR 377
E +K E +E + +P EK + + + V +++ E+ G Q +T L +
Sbjct: 1018 EEADEEDKAEDAREEEYEP-EKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQL-GAQ 1075
Query: 378 XXXXXXXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKL--RPTKMEK 435
+L +E + + E+R + + + +TQ I++ PT M++
Sbjct: 1076 SPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDE 1135
Query: 436 TPIEKEKFEDIT 447
++ D T
Sbjct: 1136 MSTPRDVMSDET 1147
>CR542201-1|CAG46998.1| 113|Homo sapiens APEG1 protein.
Length = 113
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE-NR 1577
+++ PTF ++ + V E + V G P P + W ++ + +R D+R E E
Sbjct: 16 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGL 75
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A + G YTCKAV++ G +A+L+V
Sbjct: 76 CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L + +V +G+ + ++ ++ G P P + W N + + + + GLC +
Sbjct: 20 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 79
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I A AG Y C A N++G E L +
Sbjct: 80 ILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 37.5 bits (83), Expect = 0.47
Identities = 27/103 (26%), Positives = 40/103 (38%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+ ++SD AP K + EG+ + + + G PKP V WLR +
Sbjct: 8 NRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRF 67
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
EE + G L + + D G +A N G A L V
Sbjct: 68 AEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 51.6 bits (118), Expect = 3e-05
Identities = 61/251 (24%), Positives = 98/251 (39%), Gaps = 38/251 (15%)
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV------VTTTEGKLIRLEA 1422
IL + E+ + V+S+ S A V LP+ +T G + RLE
Sbjct: 565 ILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLEC 624
Query: 1423 KAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
A+G P PQ+ W + G T+ + E ++ MPE DD IV +G
Sbjct: 625 AAVGHPAPQIAWQKDGGTDFPAARERRMH---------VMPE---DDVFFIVDVKIEDIG 672
Query: 1482 VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVT 1541
V + A S SI A L ++ P+F++ ++ V + E
Sbjct: 673 VYSCTAQNSAGSI----------------SANATLTVLET-PSFLRPLLDRTVTKGETAV 715
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
+ I G+P P++ W KD+ + ER N+ + D G YTC+ + +
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFA-AGNQLLIIVDSDVSD-AGKYTCEMSNTL 773
Query: 1602 GLAVTKAKLQV 1612
G +L V
Sbjct: 774 GTERGNVRLSV 784
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
IGV +C A+N AGS+S + + V E P L PL + TV GE L C G
Sbjct: 671 IGVYSCTAQNSAGSISANATLTVLE-------TPSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 1309 PWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
P PK++W ++ L+ T R +G + I ++ AG Y C SN G
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFF----AAGNQLLIIVDSDVSDAGKYTCEMSNTLG 774
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 51.6 bits (118), Expect = 3e-05
Identities = 61/251 (24%), Positives = 98/251 (39%), Gaps = 38/251 (15%)
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV------VTTTEGKLIRLEA 1422
IL + E+ + V+S+ S A V LP+ +T G + RLE
Sbjct: 565 ILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLEC 624
Query: 1423 KAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
A+G P PQ+ W + G T+ + E ++ MPE DD IV +G
Sbjct: 625 AAVGHPAPQIAWQKDGGTDFPAARERRMH---------VMPE---DDVFFIVDVKIEDIG 672
Query: 1482 VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVT 1541
V + A S SI A L ++ P+F++ ++ V + E
Sbjct: 673 VYSCTAQNSAGSI----------------SANATLTVLET-PSFLRPLLDRTVTKGETAV 715
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
+ I G+P P++ W KD+ + ER N+ + D G YTC+ + +
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFA-AGNQLLIIVDSDVSD-AGKYTCEMSNTL 773
Query: 1602 GLAVTKAKLQV 1612
G +L V
Sbjct: 774 GTERGNVRLSV 784
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
IGV +C A+N AGS+S + + V E P L PL + TV GE L C G
Sbjct: 671 IGVYSCTAQNSAGSISANATLTVLE-------TPSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 1309 PWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
P PK++W ++ L+ T R +G + I ++ AG Y C SN G
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFF----AAGNQLLIIVDSDVSDAGKYTCEMSNTLG 774
>BC006346-1|AAH06346.1| 113|Homo sapiens SPEG protein protein.
Length = 113
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE-NR 1577
+++ PTF ++ + V E + V G P P + W ++ + +R D+R E E
Sbjct: 16 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGL 75
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A + G YTCKAV++ G +A+L+V
Sbjct: 76 CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L + +V +G+ + ++ ++ G P P + W N + + + + GLC +
Sbjct: 20 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 79
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I A AG Y C A N++G E L +
Sbjct: 80 ILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 37.5 bits (83), Expect = 0.47
Identities = 27/103 (26%), Positives = 40/103 (38%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+ ++SD AP K + EG+ + + + G PKP V WLR +
Sbjct: 8 NRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRF 67
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
EE + G L + + D G +A N G A L V
Sbjct: 68 AEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 51.6 bits (118), Expect = 3e-05
Identities = 61/251 (24%), Positives = 98/251 (39%), Gaps = 38/251 (15%)
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV------VTTTEGKLIRLEA 1422
IL + E+ + V+S+ S A V LP+ +T G + RLE
Sbjct: 565 ILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLEC 624
Query: 1423 KAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
A+G P PQ+ W + G T+ + E ++ MPE DD IV +G
Sbjct: 625 AAVGHPAPQIAWQKDGGTDFPAARERRMH---------VMPE---DDVFFIVDVKIEDIG 672
Query: 1482 VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVT 1541
V + A S SI A L ++ P+F++ ++ V + E
Sbjct: 673 VYSCTAQNSAGSI----------------SANATLTVLET-PSFLRPLLDRTVTKGETAV 715
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
+ I G+P P++ W KD+ + ER N+ + D G YTC+ + +
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFA-AGNQLLIIVDSDVSD-AGKYTCEMSNTL 773
Query: 1602 GLAVTKAKLQV 1612
G +L V
Sbjct: 774 GTERGNVRLSV 784
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
IGV +C A+N AGS+S + + V E P L PL + TV GE L C G
Sbjct: 671 IGVYSCTAQNSAGSISANATLTVLE-------TPSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 1309 PWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
P PK++W ++ L+ T R +G + I ++ AG Y C SN G
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFF----AAGNQLLIIVDSDVSDAGKYTCEMSNTLG 774
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 51.6 bits (118), Expect = 3e-05
Identities = 61/251 (24%), Positives = 98/251 (39%), Gaps = 38/251 (15%)
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV------VTTTEGKLIRLEA 1422
IL + E+ + V+S+ S A V LP+ +T G + RLE
Sbjct: 505 ILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLEC 564
Query: 1423 KAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
A+G P PQ+ W + G T+ + E ++ MPE DD IV +G
Sbjct: 565 AAVGHPAPQIAWQKDGGTDFPAARERRMH---------VMPE---DDVFFIVDVKIEDIG 612
Query: 1482 VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVT 1541
V + A S SI A L ++ P+F++ ++ V + E
Sbjct: 613 VYSCTAQNSAGSI----------------SANATLTVLET-PSFLRPLLDRTVTKGETAV 655
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
+ I G+P P++ W KD+ + ER N+ + D G YTC+ + +
Sbjct: 656 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFA-AGNQLLIIVDSDVSD-AGKYTCEMSNTL 713
Query: 1602 GLAVTKAKLQV 1612
G +L V
Sbjct: 714 GTERGNVRLSV 724
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
IGV +C A+N AGS+S + + V E P L PL + TV GE L C G
Sbjct: 611 IGVYSCTAQNSAGSISANATLTVLE-------TPSFLRPLLDRTVTKGETAVLQCIAGGS 663
Query: 1309 PWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
P PK++W ++ L+ T R +G + I ++ AG Y C SN G
Sbjct: 664 PPPKLNWTKDDSPLVVTERHFF----AAGNQLLIIVDSDVSDAGKYTCEMSNTLG 714
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 51.6 bits (118), Expect = 3e-05
Identities = 61/251 (24%), Positives = 98/251 (39%), Gaps = 38/251 (15%)
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV------VTTTEGKLIRLEA 1422
IL + E+ + V+S+ S A V LP+ +T G + RLE
Sbjct: 565 ILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLEC 624
Query: 1423 KAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
A+G P PQ+ W + G T+ + E ++ MPE DD IV +G
Sbjct: 625 AAVGHPAPQIAWQKDGGTDFPAARERRMH---------VMPE---DDVFFIVDVKIEDIG 672
Query: 1482 VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVT 1541
V + A S SI A L ++ P+F++ ++ V + E
Sbjct: 673 VYSCTAQNSAGSI----------------SANATLTVLET-PSFLRPLLDRTVTKGETAV 715
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
+ I G+P P++ W KD+ + ER N+ + D G YTC+ + +
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFA-AGNQLLIIVDSDVSD-AGKYTCEMSNTL 773
Query: 1602 GLAVTKAKLQV 1612
G +L V
Sbjct: 774 GTERGNVRLSV 784
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
IGV +C A+N AGS+S + + V E P L PL + TV GE L C G
Sbjct: 671 IGVYSCTAQNSAGSISANATLTVLE-------TPSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 1309 PWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
P PK++W ++ L+ T R +G + I ++ AG Y C SN G
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFF----AAGNQLLIIVDSDVSDAGKYTCEMSNTLG 774
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 51.6 bits (118), Expect = 3e-05
Identities = 53/217 (24%), Positives = 82/217 (37%), Gaps = 38/217 (17%)
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLR-QGTELLQSTEYQIEELDDG 1455
E+ P+I P V T +G ++LE A+G P P + W R G + +
Sbjct: 222 EYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRH-----KS 276
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
IL +P Q+D G A N G L+ Y +P W+ + ++ A
Sbjct: 277 NGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTF--------YAQPNWIQKINDIHVA 328
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
+ EE V +E +G P P W K+ + + T +R IE
Sbjct: 329 M--------------------EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIE--- 365
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ T I G Y C A + G+ + A+L V
Sbjct: 366 -QGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSV 401
Score = 48.4 bits (110), Expect = 2e-04
Identities = 58/192 (30%), Positives = 76/192 (39%), Gaps = 33/192 (17%)
Query: 1421 EAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHL 1480
E KA G PKP +WL+ G LL QIE+ GT +T+ V D G A N
Sbjct: 336 ECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ---GTLNITI--VNLSDAGMYQCLAENKH 390
Query: 1481 GVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIV 1540
GV + A LSV + VG R T +K + +V E V
Sbjct: 391 GVIFSNAELSVIA-VGPDFSR----------------------TLLKRVTLVKVGGE--V 425
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
E +P P W K +++ +ER I N I TK G+YTC A +
Sbjct: 426 VIECKPKASPKPVYTWKKGRDILKENERITISEDGN---LRIINVTKSDAGSYTCIATNH 482
Query: 1601 IGLAVTKAKLQV 1612
G A + L V
Sbjct: 483 FGTASSTGNLVV 494
Score = 47.6 bits (108), Expect = 4e-04
Identities = 61/259 (23%), Positives = 103/259 (39%), Gaps = 39/259 (15%)
Query: 1235 KALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
K+ +LE N ++ G+ C AEN G G Q P + + + V
Sbjct: 275 KSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQ-------PNWIQKINDIHV 327
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
E + CK GRP P W N + + T I I + + +++ + AG+Y
Sbjct: 328 AMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSD-----AGMY 382
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+C A N+ G + L++ A +F+ ++K + V
Sbjct: 383 QCLAENKHGVIFSNAELSVIAVG-------------------PDFSRTLLKRVTLVKV-- 421
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
G + +E K PKP W ++G ++L+ E +I +DG L + V + D G
Sbjct: 422 -GGEVVIECKPKASPKPVYTW-KKGRDILKENE-RITISEDGN--LRIINVTKSDAGSYT 476
Query: 1474 FEAYNHLGVTATIAALSVE 1492
A NH G ++ L V+
Sbjct: 477 CIATNHFGTASSTGNLVVK 495
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
V+ PL++ + +++ LNC++ G P P I W N ++T D S + L +
Sbjct: 35 VMFPLDS----EEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPN 90
Query: 1344 EAFPEMAGIYKCTASNQFG 1362
+ + AG Y+CTA+N FG
Sbjct: 91 KT--QDAGTYQCTATNSFG 107
Score = 37.5 bits (83), Expect = 0.47
Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 5/93 (5%)
Query: 1523 PTFVKEIIPERV---HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
P F++E P EE+ V GNP P I W + + T F E
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLL 85
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTK-AKLQ 1611
T+D GTY C A + G V++ AKLQ
Sbjct: 86 INNPNKTQD-AGTYQCTATNSFGTIVSREAKLQ 117
Score = 34.7 bits (76), Expect = 3.3
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+E K ++L + G PKP +RW GT++ +++ + +G+ ++ P Q D G
Sbjct: 41 SEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVV-EGSLLINNPNKTQ-DAGTY 98
Query: 1473 VFEAYNHLG 1481
A N G
Sbjct: 99 QCTATNSFG 107
>AK128689-1|BAC87572.1| 175|Homo sapiens protein ( Homo sapiens cDNA
FLJ46856 fis, clone UTERU3010409, highly similar to
Aortic preferentially expressed protein 1. ).
Length = 175
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE-NR 1577
+++ PTF ++ + V E + V G P P + W ++ + +R D+R E E
Sbjct: 73 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGL 132
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A + G YTCKAV++ G +A+L+V
Sbjct: 133 CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 167
Score = 50.0 bits (114), Expect = 8e-05
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L + +V +G+ + ++ ++ G P P + W N + + + + GLC +
Sbjct: 77 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 136
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPS 1380
I A AG Y C A N++G E L + EY+ S
Sbjct: 137 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRG-EYLIS 174
Score = 37.5 bits (83), Expect = 0.47
Identities = 27/103 (26%), Positives = 40/103 (38%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+ ++SD AP K + EG+ + + + G PKP V WLR +
Sbjct: 65 NRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRF 124
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
EE + G L + + D G +A N G A L V
Sbjct: 125 AEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 167
>AK126500-1|BAC86568.1| 170|Homo sapiens protein ( Homo sapiens cDNA
FLJ44536 fis, clone UTERU3004992, highly similar to
Aortic preferentially expressed protein 1. ).
Length = 170
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE-NR 1577
+++ PTF ++ + V E + V G P P + W ++ + +R D+R E E
Sbjct: 73 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGL 132
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A + G YTCKAV++ G +A+L+V
Sbjct: 133 CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 167
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L + +V +G+ + ++ ++ G P P + W N + + + + GLC +
Sbjct: 77 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 136
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I A AG Y C A N++G E L +
Sbjct: 137 ILAAERGDAGFYTCKAVNEYGARQCEARLEV 167
Score = 37.5 bits (83), Expect = 0.47
Identities = 27/103 (26%), Positives = 40/103 (38%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+ ++SD AP K + EG+ + + + G PKP V WLR +
Sbjct: 65 NRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRF 124
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
EE + G L + + D G +A N G A L V
Sbjct: 125 AEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 167
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens cDNA
FLJ90440 fis, clone NT2RP3000921, weakly similar to TUMOR
SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 51.6 bits (118), Expect = 3e-05
Identities = 61/251 (24%), Positives = 98/251 (39%), Gaps = 38/251 (15%)
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTV------VTTTEGKLIRLEA 1422
IL + E+ + V+S+ S A V LP+ +T G + RLE
Sbjct: 143 ILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLEC 202
Query: 1423 KAIGIPKPQVRWLRQG-TELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLG 1481
A+G P PQ+ W + G T+ + E ++ MPE DD IV +G
Sbjct: 203 AAVGHPAPQIAWQKDGGTDFPAARERRMH---------VMPE---DDVFFIVDVKIEDIG 250
Query: 1482 VTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVT 1541
V + A S SI A L ++ P+F++ ++ V + E
Sbjct: 251 VYSCTAQNSAGSI----------------SANATLTVLET-PSFLRPLLDRTVTKGETAV 293
Query: 1542 FEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDI 1601
+ I G+P P++ W KD+ + ER N+ + D G YTC+ + +
Sbjct: 294 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFA-AGNQLLIIVDSDVSD-AGKYTCEMSNTL 351
Query: 1602 GLAVTKAKLQV 1612
G +L V
Sbjct: 352 GTERGNVRLSV 362
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
IGV +C A+N AGS+S + + V E P L PL + TV GE L C G
Sbjct: 249 IGVYSCTAQNSAGSISANATLTVLE-------TPSFLRPLLDRTVTKGETAVLQCIAGGS 301
Query: 1309 PWPKIDWFHNEK-LIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
P PK++W ++ L+ T R +G + I ++ AG Y C SN G
Sbjct: 302 PPPKLNWTKDDSPLVVTERHFF----AAGNQLLIIVDSDVSDAGKYTCEMSNTLG 352
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 51.6 bits (118), Expect = 3e-05
Identities = 53/217 (24%), Positives = 82/217 (37%), Gaps = 38/217 (17%)
Query: 1397 EFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLR-QGTELLQSTEYQIEELDDG 1455
E+ P+I P V T +G ++LE A+G P P + W R G + +
Sbjct: 222 EYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRH-----KS 276
Query: 1456 TSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAA 1515
IL +P Q+D G A N G L+ Y +P W+ + ++ A
Sbjct: 277 NGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTF--------YAQPNWIQKINDIHVA 328
Query: 1516 LKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE 1575
+ EE V +E +G P P W K+ + + T +R IE
Sbjct: 329 M--------------------EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIE--- 365
Query: 1576 NRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ T I G Y C A + G+ + A+L V
Sbjct: 366 -QGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSV 401
Score = 48.4 bits (110), Expect = 2e-04
Identities = 58/192 (30%), Positives = 76/192 (39%), Gaps = 33/192 (17%)
Query: 1421 EAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHL 1480
E KA G PKP +WL+ G LL QIE+ GT +T+ V D G A N
Sbjct: 336 ECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ---GTLNITI--VNLSDAGMYQCLAENKH 390
Query: 1481 GVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVPTFVKEIIPERVHEEEIV 1540
GV + A LSV + VG R T +K + +V E V
Sbjct: 391 GVIFSNAELSVIA-VGPDFSR----------------------TLLKRVTLVKVGGE--V 425
Query: 1541 TFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSD 1600
E +P P W K +++ +ER I N I TK G+YTC A +
Sbjct: 426 VIECKPKASPKPVYTWKKGRDILKENERITISEDGN---LRIINVTKSDAGSYTCIATNH 482
Query: 1601 IGLAVTKAKLQV 1612
G A + L V
Sbjct: 483 FGTASSTGNLVV 494
Score = 47.6 bits (108), Expect = 4e-04
Identities = 61/259 (23%), Positives = 103/259 (39%), Gaps = 39/259 (15%)
Query: 1235 KALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTV 1293
K+ +LE N ++ G+ C AEN G G Q P + + + V
Sbjct: 275 KSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQ-------PNWIQKINDIHV 327
Query: 1294 MDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIY 1353
E + CK GRP P W N + + T I I + + +++ + AG+Y
Sbjct: 328 AMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSD-----AGMY 382
Query: 1354 KCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTT 1413
+C A N+ G + L++ A +F+ ++K + V
Sbjct: 383 QCLAENKHGVIFSNAELSVIAVG-------------------PDFSRTLLKRVTLVKV-- 421
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIV 1473
G + +E K PKP W ++G ++L+ E +I +DG L + V + D G
Sbjct: 422 -GGEVVIECKPKASPKPVYTW-KKGRDILKENE-RITISEDGN--LRIINVTKSDAGSYT 476
Query: 1474 FEAYNHLGVTATIAALSVE 1492
A NH G ++ L V+
Sbjct: 477 CIATNHFGTASSTGNLVVK 495
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query: 1284 VLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIK 1343
V+ PL++ + +++ LNC++ G P P I W N ++T D S + L +
Sbjct: 35 VMFPLDS----EEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPN 90
Query: 1344 EAFPEMAGIYKCTASNQFG 1362
+ + AG Y+CTA+N FG
Sbjct: 91 KT--QDAGTYQCTATNSFG 107
Score = 37.5 bits (83), Expect = 0.47
Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 5/93 (5%)
Query: 1523 PTFVKEIIPERV---HEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
P F++E P EE+ V GNP P I W + + T F E
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLL 85
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTK-AKLQ 1611
T+D GTY C A + G V++ AKLQ
Sbjct: 86 INNPNKTQD-AGTYQCTATNSFGTIVSREAKLQ 117
Score = 34.7 bits (76), Expect = 3.3
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 1413 TEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEI 1472
+E K ++L + G PKP +RW GT++ +++ + +G+ ++ P Q D G
Sbjct: 41 SEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVV-EGSLLINNPNKTQ-DAGTY 98
Query: 1473 VFEAYNHLG 1481
A N G
Sbjct: 99 QCTATNSFG 107
>AC053503-3|AAY15052.1| 113|Homo sapiens unknown protein.
Length = 113
Score = 51.6 bits (118), Expect = 3e-05
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 1519 TQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKE-NR 1577
+++ PTF ++ + V E + V G P P + W ++ + +R D+R E E
Sbjct: 16 SKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGL 75
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
I A + G YTCKAV++ G +A+L+V
Sbjct: 76 CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/91 (25%), Positives = 41/91 (45%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIH 1341
P L + +V +G+ + ++ ++ G P P + W N + + + + GLC +
Sbjct: 20 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 79
Query: 1342 IKEAFPEMAGIYKCTASNQFGKCSTECILNI 1372
I A AG Y C A N++G E L +
Sbjct: 80 ILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
Score = 37.5 bits (83), Expect = 0.47
Identities = 27/103 (26%), Positives = 40/103 (38%)
Query: 1389 DEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQ 1448
+ ++SD AP K + EG+ + + + G PKP V WLR +
Sbjct: 8 NRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRF 67
Query: 1449 IEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
EE + G L + + D G +A N G A L V
Sbjct: 68 AEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 110
>AL133563-1|CAB63717.1| 1132|Homo sapiens hypothetical protein
protein.
Length = 1132
Score = 51.2 bits (117), Expect = 4e-05
Identities = 77/357 (21%), Positives = 149/357 (41%), Gaps = 29/357 (8%)
Query: 165 SEKKDLLQVSTHED-TNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKGVN 223
+EKK+ + E+ + K++ E + + +S RK E +V GV
Sbjct: 145 AEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVI 204
Query: 224 EPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTK 283
K +T +D NE + + ++ KK+ + E K++ K+K P ++ +K
Sbjct: 205 PASE---EKAETPTAAEDDNEGDKKKKDKKKKKGEK-EEKEKEKKKGP-SKATVKAMQEA 259
Query: 284 VEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNK 343
+ K E+E R+ +E+ + EL+ +R+ E+ E QE + + +K K
Sbjct: 260 LAKLKEEEE----------RQKREEEERIKRLEELEAKRKEEERLE--QEKRERKKQKEK 307
Query: 344 LLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESK 403
+ + +E K T + QRE + E LK ++ +P+ +K K
Sbjct: 308 ERKERLKKEGKLLT--KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 365
Query: 404 ETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKT-----PIEKEKFEDITLKPTRKQSLVD 458
+ + + + + E ++ + E+T P E+E ED L + D
Sbjct: 366 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA-SD 424
Query: 459 EITEEVCALK---SALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEETPQEEVV 512
E TE+V K ++ E+EE + ++ E+ EE + G+ + E ++E V
Sbjct: 425 EETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 481
>AB018284-1|BAA34461.2| 1222|Homo sapiens KIAA0741 protein protein.
Length = 1222
Score = 51.2 bits (117), Expect = 4e-05
Identities = 77/357 (21%), Positives = 149/357 (41%), Gaps = 29/357 (8%)
Query: 165 SEKKDLLQVSTHED-TNILKVENLESVNVDTTSSKLETKSWRKPRLEESLEEVGPTKGVN 223
+EKK+ + E+ + K++ E + + +S RK E +V GV
Sbjct: 235 AEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVI 294
Query: 224 EPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTK 283
K +T +D NE + + ++ KK+ + E K++ K+K P ++ +K
Sbjct: 295 PASE---EKAETPTAAEDDNEGDKKKKDKKKKKGEK-EEKEKEKKKGP-SKATVKAMQEA 349
Query: 284 VEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNERQITEKKESLQETQLQPTEKNK 343
+ K E+E R+ +E+ + EL+ +R+ E+ E QE + + +K K
Sbjct: 350 LAKLKEEEE----------RQKREEEERIKRLEELEAKRKEEERLE--QEKRERKKQKEK 397
Query: 344 LLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXXXXXXXXXXSLKPVLTTEKESK 403
+ + +E K T + QRE + E LK ++ +P+ +K K
Sbjct: 398 ERKERLKKEGKLLT--KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 455
Query: 404 ETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKT-----PIEKEKFEDITLKPTRKQSLVD 458
+ + + + + E ++ + E+T P E+E ED L + D
Sbjct: 456 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA-SD 514
Query: 459 EITEEVCALK---SALDDIEKEEHKPDKVSENNAPEERKWPTGKRQPKEETPQEEVV 512
E TE+V K ++ E+EE + ++ E+ EE + G+ + E ++E V
Sbjct: 515 EETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 571
>X69090-1|CAA48833.1| 1451|Homo sapiens 190kD protein protein.
Length = 1451
Score = 50.8 bits (116), Expect = 5e-05
Identities = 43/180 (23%), Positives = 74/180 (41%), Gaps = 5/180 (2%)
Query: 1312 KIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECILN 1371
K++W HN I + + + + I E P G Y + GK + ++
Sbjct: 1255 KVNWSHNGSAIRYSDRVKTGVTGEQIW-LQINEPTPNDKGKYVMELFD--GKTGHQKTVD 1311
Query: 1372 IEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQ 1431
+ Y + +E L ++ + E+ R++ LP VVT EGK + L G P P+
Sbjct: 1312 LSGQAYDEAYAEFQRL--KQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPE 1369
Query: 1432 VRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSV 1491
V WL+ L Q+ ++ T+ T+ V D+G+ N G + +SV
Sbjct: 1370 VSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1429
Score = 38.7 bits (86), Expect = 0.20
Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Query: 1281 APLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARD--ITISRQKSGLC 1338
AP + + TV + E + L+C I G P P++ W+ N+ I + I + G+
Sbjct: 140 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 199
Query: 1339 EIHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYE 1376
+ I E Y+ +A N G+ S + ++ Y+
Sbjct: 200 TLEINACDFEDTAQYRASAMNVKGELSAYASVVVKRYK 237
Score = 38.7 bits (86), Expect = 0.20
Identities = 16/81 (19%), Positives = 36/81 (44%)
Query: 1292 TVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAG 1351
T+ +G+ ++L C + G P P++ W NEK + + + I +G
Sbjct: 1349 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSG 1408
Query: 1352 IYKCTASNQFGKCSTECILNI 1372
Y N++G +++ +++
Sbjct: 1409 KYGLVVKNKYGSETSDFTVSV 1429
Score = 35.1 bits (77), Expect = 2.5
Identities = 18/55 (32%), Positives = 23/55 (41%)
Query: 1550 PTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLA 1604
P E W KD R +E+K N+T T K D G Y+C G+A
Sbjct: 931 PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIA 985
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 50.8 bits (116), Expect = 5e-05
Identities = 71/266 (26%), Positives = 105/266 (39%), Gaps = 48/266 (18%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSS---IVEEQTCIDGDAPLVLAP 1287
IQP L L +N+ G TC AEN G ++ T + GD L L
Sbjct: 984 IQPSGEL--LVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRL-- 1039
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFP 1347
G+R+ L C G P P+I W N++ + +S Q G +
Sbjct: 1040 --------GDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGG-STLQRAAVSR 1086
Query: 1348 EMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALP 1407
E +G Y C A N+ G+ +A +V V E VL E S + E P
Sbjct: 1087 EDSGTYVCWAENRVGR--------TQAVSFV-HVKEAPVLQGEAFSYLVE---------P 1128
Query: 1408 TVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQD 1467
G I+L+ G P P + W++ G L S + +L +G+ LT+ +D
Sbjct: 1129 V------GGSIQLDCVVRGDPVPDIHWIKDGLPLRGS--HLRHQLQNGS--LTIHRTERD 1178
Query: 1468 DTGEIVFEAYNHLGVTATIAALSVES 1493
D G A N +GV + L ++S
Sbjct: 1179 DAGRYQCLAENEMGVAKKVVILVLQS 1204
Score = 49.2 bits (112), Expect = 1e-04
Identities = 54/255 (21%), Positives = 96/255 (37%), Gaps = 35/255 (13%)
Query: 1237 LNVLEENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDG 1296
L + E +S G+ +C+ N AG + + V+ + E + + G
Sbjct: 1 LEIQEAQVSDK--GLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKT------ETVSQVAG 52
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCT 1356
+ L C + G P P + W + +E++ + + G + + P AG Y C
Sbjct: 53 SPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV-SRGG--RLQLSRLQPAQAGTYTCV 109
Query: 1357 ASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGK 1416
A N + + ++ A P + V + EG+
Sbjct: 110 AENTQAEARKDFVV---AVLVAPRIRSSGVAREHHV--------------------LEGQ 146
Query: 1417 LIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEA 1476
+RL+ +A G P P V WL+ G+ L Q + DG S L + ++ D G A
Sbjct: 147 EVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS-LVLKGLWASDAGAYTCVA 205
Query: 1477 YNHLGVTATIAALSV 1491
+N G A + ++V
Sbjct: 206 HNPAGEDARLHTVNV 220
Score = 49.2 bits (112), Expect = 1e-04
Identities = 63/252 (25%), Positives = 99/252 (39%), Gaps = 41/252 (16%)
Query: 1244 ISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDA-PLVLAPLENTTVMDGERISLN 1302
+S++ G C AEN G V+E + G+A ++ P+ G I L+
Sbjct: 1084 VSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPV-------GGSIQLD 1136
Query: 1303 CKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
C + G P P I W + + + + ++G IH E + AG Y+C A N+ G
Sbjct: 1137 CVVRGDPVPDIHWIKDGLPLRGSH--LRHQLQNGSLTIHRTER--DDAGRYQCLAENEMG 1192
Query: 1363 KCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEA 1422
IL +++ AP + + P +T G + L
Sbjct: 1193 VAKKVVILVLQS------------------------AP-VFQVEPQDMTVRSGDDVALRC 1227
Query: 1423 KAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGV 1482
+A G P P + WL+ G L S ++ L DG+ L + V D G A+N LG
Sbjct: 1228 QATGEPTPTIEWLQAGQPLRASR--RLRTLPDGS--LWLENVETGDAGTYDCVAHNLLGS 1283
Query: 1483 TATIAALSVESI 1494
A L V +
Sbjct: 1284 ATARAFLVVRGM 1295
Score = 43.6 bits (98), Expect = 0.007
Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 10/123 (8%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G C A+N AGS +V+ I+ P + + +G L CK G P
Sbjct: 910 GNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP-------DLSTTEGSHAFLPCKARGSP 962
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTECI 1369
P I W + + + A + Q SG E+ +K + AG Y CTA N G+
Sbjct: 963 EPNITWDKDGQPVSGAEG-KFTIQPSG--ELLVKNLEGQDAGTYTCTAENAVGRARRRVH 1019
Query: 1370 LNI 1372
L I
Sbjct: 1020 LTI 1022
Score = 42.3 bits (95), Expect = 0.016
Identities = 51/190 (26%), Positives = 72/190 (37%), Gaps = 38/190 (20%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTT-VMDGERISLNCKILGR 1308
G TC A N AG + + + A V+ PL + + E + L C+ G
Sbjct: 820 GRYTCSARNSAG--------VAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGI 871
Query: 1309 PWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P P I W ++ + A ++ G ++ I A PE AG Y C A N G
Sbjct: 872 PRPTITW--QKEGLNVATGVSTQVLPGG--QLRIAHASPEDAGNYLCIAKNSAGSAM--- 924
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
KT V + P I LP ++TTEG L KA G P
Sbjct: 925 ---------------------GKTRLVVQVPPVIENGLPD-LSTTEGSHAFLPCKARGSP 962
Query: 1429 KPQVRWLRQG 1438
+P + W + G
Sbjct: 963 EPNITWDKDG 972
Score = 41.1 bits (92), Expect = 0.038
Identities = 47/183 (25%), Positives = 69/183 (37%), Gaps = 32/183 (17%)
Query: 1299 ISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTAS 1358
+ L C G P P + W + AR SG EI +A P AG Y C+A
Sbjct: 771 VVLTCHSTGIPAPTVSWSKAGAQLG-ARGSGYRVSPSGALEIG--QALPIHAGRYTCSAR 827
Query: 1359 NQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLI 1418
N G L ++A +P +VK LP+VV + +
Sbjct: 828 NSAGVAHKHVFLTVQA------------------------SP-VVKPLPSVVRAVAEEEV 862
Query: 1419 RLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYN 1478
L +A GIP+P + W ++G + Q+ L G L + +D G + A N
Sbjct: 863 LLPCEASGIPRPTITWQKEGLNVATGVSTQV--LPGGQ--LRIAHASPEDAGNYLCIAKN 918
Query: 1479 HLG 1481
G
Sbjct: 919 SAG 921
Score = 40.7 bits (91), Expect = 0.050
Identities = 66/262 (25%), Positives = 102/262 (38%), Gaps = 38/262 (14%)
Query: 1221 KDSTELTPRIIQPLKALNVLE-ENISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDG 1279
KD LT R+ +A VL EN+ G+ TC AE+ AG++ S V+ I G
Sbjct: 442 KDGQALT-RLENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG 500
Query: 1280 DAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCE 1339
P + G+ + L C + P PKI W H + ++ D + G
Sbjct: 501 PR----GPRFVVGLAPGQLV-LECSVEAEPAPKITW-HRDGIV-LQEDAHTQFPERGRF- 552
Query: 1340 IHIKEAFPEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+ ++ +G Y CTA N G ST +E + VP+
Sbjct: 553 LQLQALSTADSGDYSCTARNAAG--STSVAFRVEIHT-VPT------------------- 590
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
+++ P V + + L +A G+P P V W R+ L + E L +G+ L
Sbjct: 591 ---IRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVPLDPRSPRFEILPEGS--L 644
Query: 1460 TMPEVYQDDTGEIVFEAYNHLG 1481
+ V D G + A N G
Sbjct: 645 RIQPVLAQDAGHYLCLASNSAG 666
Score = 37.1 bits (82), Expect = 0.61
Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ + + G+P P+I W KD +R + ++ + TI + +D G Y C A +
Sbjct: 1133 IQLDCVVRGDPVPDIHWIKDGLPLRGSH---LRHQLQNGSLTIHRTERDDAGRYQCLAEN 1189
Query: 1600 DIGLA 1604
++G+A
Sbjct: 1190 EMGVA 1194
Score = 33.5 bits (73), Expect = 7.6
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Query: 1520 QSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTT 1579
QS P F E V + V +G PTP I W + + +R R + + +
Sbjct: 1203 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRR--LRTLPDGSL 1260
Query: 1580 CTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
T D GTY C A + +G A +A L V
Sbjct: 1261 WLENVETGD-AGTYDCVAHNLLGSATARAFLVV 1292
>AL050093-1|CAB43265.1| 145|Homo sapiens hypothetical protein
protein.
Length = 145
Score = 50.8 bits (116), Expect = 5e-05
Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDW-FHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
L+NT V DG + L C++LG P P+I W NE L + +++ + G + I+ A
Sbjct: 2 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 61
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAY 1375
E AG Y +A N+ G S C ++ Y
Sbjct: 62 KEDAGWYTVSAKNEAGIVS--CTARLDVY 88
Score = 44.8 bits (101), Expect = 0.003
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Query: 1414 EGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTE-YQIEELDDGTSILTMPEVYQDDTGEI 1472
+G +RLE + +G+P PQ+ W ++ L ST+ + + + G L + ++D G
Sbjct: 9 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 68
Query: 1473 VFEAYNHLGVTATIAALSVESIVGTQ-EYRKPEWVTHMEELQAAL 1516
A N G+ + A L V + Q + KP+ V AAL
Sbjct: 69 TVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAAL 113
Score = 39.5 bits (88), Expect = 0.12
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIR--TDERFIIENKENRTTCTIKKATKDLEGTYTCKA 1597
V E G P P+I W K+N+ + TD + ++ I+ ATK+ G YT A
Sbjct: 13 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 72
Query: 1598 VSDIGLAVTKAKLQVF 1613
++ G+ A+L V+
Sbjct: 73 KNEAGIVSCTARLDVY 88
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 50.4 bits (115), Expect = 6e-05
Identities = 84/373 (22%), Positives = 141/373 (37%), Gaps = 64/373 (17%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-----ENTTVMDGERISLNCKI 1305
++T ++ AG G+++V E+ + ++ P N V + C+
Sbjct: 187 MITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEA 246
Query: 1306 LGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
G P P + W ++ + +R I + + I++ G Y C A N GK
Sbjct: 247 RGDPVPTVRWRKDDGELPKSR-YEIRDDHT----LKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 1366 TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAI 1425
L ++ P +VK VV G+ + + +A
Sbjct: 302 ASATLTVQVGSEPPHF--------------------VVKPRDQVVAL--GRTVTFQCEAT 339
Query: 1426 GIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-----LTMPEVYQDDTGEIVFEAYNHL 1480
G P+P + W R+G++ L + YQ + S+ LT+ V + D G + + N
Sbjct: 340 GNPQPAIFWRREGSQNLLFS-YQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVA 398
Query: 1481 GVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVP-TFVKEIIPERVHEEEI 1539
G T A L V ++ R P + Q + T +V TFV
Sbjct: 399 GSIITKAYLEVTDVIAD---RPPPVIR-----QGPVNQTVAVDGTFV------------- 437
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ +G+P P ILW KD ++ T + I+ EN I+ A G YTC A +
Sbjct: 438 --LSCVATGSPVPTILWRKDGVLVSTQDS-RIKQLEN-GVLQIRYAKLGDTGRYTCIAST 493
Query: 1600 DIGLAVTKAKLQV 1612
G A A ++V
Sbjct: 494 PSGEATWSAYIEV 506
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
N+ + +G C+ N AGS+ T V + D P++ P+ T +DG + L
Sbjct: 381 NVQRSDVGYYICQTLNVAGSIITKAYLEVTD-VIADRPPPVIRQGPVNQTVAVDGTFV-L 438
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+C G P P I W + L+ T +D I + ++G+ + I+ A G Y C AS
Sbjct: 439 SCVATGSPVPTILWRKDGVLVST-QDSRIKQLENGV--LQIRYAKLGDTGRYTCIASTPS 495
Query: 1362 GKCSTECILNIEAY 1375
G+ + + ++ +
Sbjct: 496 GEATWSAYIEVQEF 509
Score = 46.8 bits (106), Expect = 8e-04
Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ---KSG-- 1336
P ++ + V GE +LNCK GRP P I+W+ + +ET +D S + SG
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 1337 --LCEIHIKEAFPEMAGIYKCTASNQFGK 1363
L +H +++ P+ G+Y C A N G+
Sbjct: 89 FFLRIVHGRKSRPD-EGVYVCVARNYLGE 116
Score = 43.6 bits (98), Expect = 0.007
Identities = 54/248 (21%), Positives = 93/248 (37%), Gaps = 30/248 (12%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G TC AEN G S + V+ + + P + + V G ++ C+ G
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQ----VGSEPPHFVVKPRDQVVALGRTVTFQCEATGN 341
Query: 1309 PWPKIDWFH--NEKLIETARDITISRQ--KSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
P P I W ++ L+ + + S + S ++ I G Y C N G
Sbjct: 342 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 401
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKA 1424
T+ L + DV++D P +++ P T L A
Sbjct: 402 ITKAYLEV-----------TDVIADR--------PPPVIRQGPVNQTVAVDGTFVLSCVA 442
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
G P P + W + G L+ + + +I++L++G +L + DTG A G
Sbjct: 443 TGSPVPTILWRKDGV-LVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 1485 TIAALSVE 1492
A + V+
Sbjct: 500 WSAYIEVQ 507
Score = 33.5 bits (73), Expect = 7.6
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG 1438
E+F PRIV+ P+ + ++G+ L KA G P P + W + G
Sbjct: 25 EDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGG 66
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 50.4 bits (115), Expect = 6e-05
Identities = 84/373 (22%), Positives = 141/373 (37%), Gaps = 64/373 (17%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-----ENTTVMDGERISLNCKI 1305
++T ++ AG G+++V E+ + ++ P N V + C+
Sbjct: 187 MITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEA 246
Query: 1306 LGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
G P P + W ++ + +R I + + I++ G Y C A N GK
Sbjct: 247 RGDPVPTVRWRKDDGELPKSR-YEIRDDHT----LKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 1366 TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAI 1425
L ++ P +VK VV G+ + + +A
Sbjct: 302 ASATLTVQVGSEPPHF--------------------VVKPRDQVVAL--GRTVTFQCEAT 339
Query: 1426 GIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-----LTMPEVYQDDTGEIVFEAYNHL 1480
G P+P + W R+G++ L + YQ + S+ LT+ V + D G + + N
Sbjct: 340 GNPQPAIFWRREGSQNLLFS-YQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVA 398
Query: 1481 GVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVP-TFVKEIIPERVHEEEI 1539
G T A L V ++ R P + Q + T +V TFV
Sbjct: 399 GSIITKAYLEVTDVIAD---RPPPVIR-----QGPVNQTVAVDGTFV------------- 437
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ +G+P P ILW KD ++ T + I+ EN I+ A G YTC A +
Sbjct: 438 --LSCVATGSPVPTILWRKDGVLVSTQDS-RIKQLEN-GVLQIRYAKLGDTGRYTCIAST 493
Query: 1600 DIGLAVTKAKLQV 1612
G A A ++V
Sbjct: 494 PSGEATWSAYIEV 506
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
N+ + +G C+ N AGS+ T V + D P++ P+ T +DG + L
Sbjct: 381 NVQRSDVGYYICQTLNVAGSIITKAYLEVTD-VIADRPPPVIRQGPVNQTVAVDGTFV-L 438
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+C G P P I W + L+ T +D I + ++G+ + I+ A G Y C AS
Sbjct: 439 SCVATGSPVPTILWRKDGVLVST-QDSRIKQLENGV--LQIRYAKLGDTGRYTCIASTPS 495
Query: 1362 GKCSTECILNIEAY 1375
G+ + + ++ +
Sbjct: 496 GEATWSAYIEVQEF 509
Score = 46.8 bits (106), Expect = 8e-04
Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ---KSG-- 1336
P ++ + V GE +LNCK GRP P I+W+ + +ET +D S + SG
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 1337 --LCEIHIKEAFPEMAGIYKCTASNQFGK 1363
L +H +++ P+ G+Y C A N G+
Sbjct: 89 FFLRIVHGRKSRPD-EGVYVCVARNYLGE 116
Score = 43.6 bits (98), Expect = 0.007
Identities = 54/248 (21%), Positives = 93/248 (37%), Gaps = 30/248 (12%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G TC AEN G S + V+ + + P + + V G ++ C+ G
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQ----VGSEPPHFVVKPRDQVVALGRTVTFQCEATGN 341
Query: 1309 PWPKIDWFH--NEKLIETARDITISRQ--KSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
P P I W ++ L+ + + S + S ++ I G Y C N G
Sbjct: 342 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 401
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKA 1424
T+ L + DV++D P +++ P T L A
Sbjct: 402 ITKAYLEV-----------TDVIADR--------PPPVIRQGPVNQTVAVDGTFVLSCVA 442
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
G P P + W + G L+ + + +I++L++G +L + DTG A G
Sbjct: 443 TGSPVPTILWRKDGV-LVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 1485 TIAALSVE 1492
A + V+
Sbjct: 500 WSAYIEVQ 507
Score = 33.9 bits (74), Expect = 5.7
Identities = 59/228 (25%), Positives = 93/228 (40%), Gaps = 38/228 (16%)
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG--TELLQSTEYQIEELD 1453
E+F PRIV+ P+ + ++G+ L KA G P P + W + G E + L
Sbjct: 25 EDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLL 83
Query: 1454 DGTSILTMPEVY----QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
S+ + V+ + D G V A N+LG + A S+E + ++R+ +
Sbjct: 84 PSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNA-SLEVAILRDDFRQ-----NP 137
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDER 1568
++ A+ P V E P R G+P P I W KD + DER
Sbjct: 138 SDVMVAV----GEPA-VMECQPPR--------------GHPEPTISWKKDGSPLDDKDER 178
Query: 1569 FIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK-AKLQVFQR 1615
I + T T K G Y C + +G ++ A+L V +R
Sbjct: 179 ITIRGGKLMITYTRKSDA----GKYVCVGTNMVGERESEVAELTVLER 222
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 50.4 bits (115), Expect = 6e-05
Identities = 84/373 (22%), Positives = 141/373 (37%), Gaps = 64/373 (17%)
Query: 1251 VVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPL-----ENTTVMDGERISLNCKI 1305
++T ++ AG G+++V E+ + ++ P N V + C+
Sbjct: 187 MITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEA 246
Query: 1306 LGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCS 1365
G P P + W ++ + +R I + + I++ G Y C A N GK
Sbjct: 247 RGDPVPTVRWRKDDGELPKSR-YEIRDDHT----LKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 1366 TECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAI 1425
L ++ P +VK VV G+ + + +A
Sbjct: 302 ASATLTVQVGSEPPHF--------------------VVKPRDQVVAL--GRTVTFQCEAT 339
Query: 1426 GIPKPQVRWLRQGTELLQSTEYQIEELDDGTSI-----LTMPEVYQDDTGEIVFEAYNHL 1480
G P+P + W R+G++ L + YQ + S+ LT+ V + D G + + N
Sbjct: 340 GNPQPAIFWRREGSQNLLFS-YQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVA 398
Query: 1481 GVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALKATQSVP-TFVKEIIPERVHEEEI 1539
G T A L V ++ R P + Q + T +V TFV
Sbjct: 399 GSIITKAYLEVTDVIAD---RPPPVIR-----QGPVNQTVAVDGTFV------------- 437
Query: 1540 VTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVS 1599
+ +G+P P ILW KD ++ T + I+ EN I+ A G YTC A +
Sbjct: 438 --LSCVATGSPVPTILWRKDGVLVSTQDS-RIKQLEN-GVLQIRYAKLGDTGRYTCIAST 493
Query: 1600 DIGLAVTKAKLQV 1612
G A A ++V
Sbjct: 494 PSGEATWSAYIEV 506
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
N+ + +G C+ N AGS+ T V + D P++ P+ T +DG + L
Sbjct: 381 NVQRSDVGYYICQTLNVAGSIITKAYLEVTD-VIADRPPPVIRQGPVNQTVAVDGTFV-L 438
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+C G P P I W + L+ T +D I + ++G+ + I+ A G Y C AS
Sbjct: 439 SCVATGSPVPTILWRKDGVLVST-QDSRIKQLENGV--LQIRYAKLGDTGRYTCIASTPS 495
Query: 1362 GKCSTECILNIEAY 1375
G+ + + ++ +
Sbjct: 496 GEATWSAYIEVQEF 509
Score = 46.8 bits (106), Expect = 8e-04
Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
Query: 1282 PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQ---KSG-- 1336
P ++ + V GE +LNCK GRP P I+W+ + +ET +D S + SG
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 1337 --LCEIHIKEAFPEMAGIYKCTASNQFGK 1363
L +H +++ P+ G+Y C A N G+
Sbjct: 89 FFLRIVHGRKSRPD-EGVYVCVARNYLGE 116
Score = 43.6 bits (98), Expect = 0.007
Identities = 54/248 (21%), Positives = 93/248 (37%), Gaps = 30/248 (12%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G TC AEN G S + V+ + + P + + V G ++ C+ G
Sbjct: 286 MGSYTCVAENMVGKAEASATLTVQ----VGSEPPHFVVKPRDQVVALGRTVTFQCEATGN 341
Query: 1309 PWPKIDWFH--NEKLIETARDITISRQ--KSGLCEIHIKEAFPEMAGIYKCTASNQFGKC 1364
P P I W ++ L+ + + S + S ++ I G Y C N G
Sbjct: 342 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 401
Query: 1365 STECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKA 1424
T+ L + DV++D P +++ P T L A
Sbjct: 402 ITKAYLEV-----------TDVIADR--------PPPVIRQGPVNQTVAVDGTFVLSCVA 442
Query: 1425 IGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTA 1484
G P P + W + G L+ + + +I++L++G +L + DTG A G
Sbjct: 443 TGSPVPTILWRKDGV-LVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 1485 TIAALSVE 1492
A + V+
Sbjct: 500 WSAYIEVQ 507
Score = 33.9 bits (74), Expect = 5.7
Identities = 59/228 (25%), Positives = 93/228 (40%), Gaps = 38/228 (16%)
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG--TELLQSTEYQIEELD 1453
E+F PRIV+ P+ + ++G+ L KA G P P + W + G E + L
Sbjct: 25 EDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLL 83
Query: 1454 DGTSILTMPEVY----QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
S+ + V+ + D G V A N+LG + A S+E + ++R+ +
Sbjct: 84 PSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNA-SLEVAILRDDFRQ-----NP 137
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDER 1568
++ A+ P V E P R G+P P I W KD + DER
Sbjct: 138 SDVMVAV----GEPA-VMECQPPR--------------GHPEPTISWKKDGSPLDDKDER 178
Query: 1569 FIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK-AKLQVFQR 1615
I + T T K G Y C + +G ++ A+L V +R
Sbjct: 179 ITIRGGKLMITYTRKSDA----GKYVCVGTNMVGERESEVAELTVLER 222
>BC014276-1|AAH14276.2| 417|Homo sapiens LRIG1 protein protein.
Length = 417
Score = 50.4 bits (115), Expect = 6e-05
Identities = 29/97 (29%), Positives = 43/97 (44%), Gaps = 3/97 (3%)
Query: 1266 SGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETA 1325
S SI T + P ++ PLE+ V GE ++L CK G P P+I WF ++ +
Sbjct: 1 SAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLT 60
Query: 1326 RDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
++ L ++ E AG Y C SN G
Sbjct: 61 ERHHLTPDNQLLV---VQNVVAEDAGRYTCEMSNTLG 94
Score = 39.9 bits (89), Expect = 0.087
Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +V L V + G+ + L+ KA G P P++ W + G L TE L +L
Sbjct: 17 PSLVVPLEDRVVSV-GETVALQCKATGNPPPRITWFK-GDRPLSLTER--HHLTPDNQLL 72
Query: 1460 TMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQE 1499
+ V +D G E N LG + LSV G ++
Sbjct: 73 VVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAAGCRK 112
Score = 37.5 bits (83), Expect = 0.47
Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+ V + V E V + +GNP P I W+K ++ + ER + +N+ +
Sbjct: 17 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHL-TPDNQ-LLVV 74
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ + G YTC+ + +G ++L V
Sbjct: 75 QNVVAEDAGRYTCEMSNTLGTERAHSQLSV 104
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 50.4 bits (115), Expect = 6e-05
Identities = 54/209 (25%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 1297 ERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCT 1356
E + + C+ +G P P + W+ + I ++ SG + I++ PE +GI++C
Sbjct: 402 ETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASG--GLRIQKLRPEDSGIFQCF 459
Query: 1357 ASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGK 1416
ASN+ G+ T L DV AP + P T T+G
Sbjct: 460 ASNEGGEIQTHTYL-----------------------DVTNIAP-VFTQRPVDTTVTDGM 495
Query: 1417 LIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE---LDDGTSILTMPEVYQDDTGEIV 1473
L + G PKP + W R+ +L S +I L+ G L + V+ D G
Sbjct: 496 TAILRCEVSGAPKPAITWKRE-NHILASGSVRIPRFMLLESGG--LQIAPVFIQDAGNYT 552
Query: 1474 FEAYN---HLGVTATIAALSVESIVGTQE 1499
A N L +AT+ + SIV E
Sbjct: 553 CYAANTEGSLNASATLTVWNRTSIVHPPE 581
Score = 42.7 bits (96), Expect = 0.012
Identities = 36/126 (28%), Positives = 51/126 (40%), Gaps = 12/126 (9%)
Query: 1250 GVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
G+ C A N G + T + AP+ +TTV DG L C++ G P
Sbjct: 454 GIFQCFASNEGGEIQT------HTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAP 507
Query: 1310 WPKIDWFHNEKLIETARDITISR---QKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCST 1366
P I W E I + + I R +SG + I F + AG Y C A+N G +
Sbjct: 508 KPAITW-KRENHILASGSVRIPRFMLLESG--GLQIAPVFIQDAGNYTCYAANTEGSLNA 564
Query: 1367 ECILNI 1372
L +
Sbjct: 565 SATLTV 570
>Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 50.0 bits (114), Expect = 8e-05
Identities = 78/341 (22%), Positives = 138/341 (40%), Gaps = 44/341 (12%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
+E VK +E + RK +E+K+ Q D + + V KL
Sbjct: 173 KEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVK 263
+L + L E E R K + LK+K +E ++ ++Q K ++ K
Sbjct: 233 VEIEKLNKELASKN-----KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEK 287
Query: 264 D-ESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
D E QK P +A + K++K K+ +++ ++ MDE E+ ++ R
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKAR 347
Query: 323 QITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXX 382
Q E +E ++E L EN V + R +EE +++ L
Sbjct: 348 Q--EFEERMEEESQSQGRDLTLEENQVKK-------YHRLKEEASKRAATL--------- 389
Query: 383 XXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEK 442
+ + ++ K +DR++ ++ +K T+ IK + ++E+ EK
Sbjct: 390 ---------AQELEKFNRDQKADQDRLDLEERKKVE---TEAKIKQKLREIEENQKRIEK 437
Query: 443 FEDITLKPTRKQSLVD------EITEEVCALKSALDDIEKE 477
E+ T KQSL + E+TEEV K +D+I KE
Sbjct: 438 LEEYI--TTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
Score = 33.5 bits (73), Expect = 7.6
Identities = 27/134 (20%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 237 EILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIED 296
E +K +NE + E + Q T+ D K ++ Q+ + + V+K E EK++
Sbjct: 795 EKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKK 854
Query: 297 VALKPVRKDSLMDEKSSEISELQNER-----QITEKKESLQETQLQPTEKNKLLENIVSE 351
+ R ++DE +++ +L+N+ ++ +K ++E + + NK + ++ E
Sbjct: 855 ---EEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKE 911
Query: 352 ESKESTGKRRQREE 365
+ T ++R +
Sbjct: 912 VTAIETKLEQKRSD 925
>S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein.
Length = 1233
Score = 50.0 bits (114), Expect = 8e-05
Identities = 78/341 (22%), Positives = 138/341 (40%), Gaps = 44/341 (12%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
+E VK +E + RK +E+K+ Q D + + V KL
Sbjct: 173 KEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVK 263
+L + L E E R K + LK+K +E ++ ++Q K ++ K
Sbjct: 233 VEIEKLNKELASKN-----KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEK 287
Query: 264 D-ESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
D E QK P +A + K++K K+ +++ ++ MDE E+ ++ R
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKAR 347
Query: 323 QITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXX 382
Q E +E ++E L EN V + R +EE +++ L
Sbjct: 348 Q--EFEERMEEESQSQGRDLTLEENQVKK-------YHRLKEEASKRAATL--------- 389
Query: 383 XXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEK 442
+ + ++ K +DR++ ++ +K T+ IK + ++E+ EK
Sbjct: 390 ---------AQELEKFNRDQKADQDRLDLEERKKVE---TEAKIKQKLREIEENQKRIEK 437
Query: 443 FEDITLKPTRKQSLVD------EITEEVCALKSALDDIEKE 477
E+ T KQSL + E+TEEV K +D+I KE
Sbjct: 438 LEEYI--TTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
Score = 33.5 bits (73), Expect = 7.6
Identities = 27/134 (20%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 237 EILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIED 296
E +K +NE + E + Q T+ D K ++ Q+ + + V+K E EK++
Sbjct: 795 EKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKK 854
Query: 297 VALKPVRKDSLMDEKSSEISELQNER-----QITEKKESLQETQLQPTEKNKLLENIVSE 351
+ R ++DE +++ +L+N+ ++ +K ++E + + NK + ++ E
Sbjct: 855 ---EEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKE 911
Query: 352 ESKESTGKRRQREE 365
+ T ++R +
Sbjct: 912 VTAIETKLEQKRSD 925
>D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein.
Length = 1233
Score = 50.0 bits (114), Expect = 8e-05
Identities = 78/341 (22%), Positives = 138/341 (40%), Gaps = 44/341 (12%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
+E VK +E + RK +E+K+ Q D + + V KL
Sbjct: 173 KEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVK 263
+L + L E E R K + LK+K +E ++ ++Q K ++ K
Sbjct: 233 VEIEKLNKELASKN-----KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEK 287
Query: 264 D-ESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
D E QK P +A + K++K K+ +++ ++ MDE E+ ++ R
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKAR 347
Query: 323 QITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXX 382
Q E +E ++E L EN V + R +EE +++ L
Sbjct: 348 Q--EFEERMEEESQSQGRDLTLEENQVKK-------YHRLKEEASKRAATL--------- 389
Query: 383 XXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEK 442
+ + ++ K +DR++ ++ +K T+ IK + ++E+ EK
Sbjct: 390 ---------AQELEKFNRDQKADQDRLDLEERKKVE---TEAKIKQKLREIEENQKRIEK 437
Query: 443 FEDITLKPTRKQSLVD------EITEEVCALKSALDDIEKE 477
E+ T KQSL + E+TEEV K +D+I KE
Sbjct: 438 LEEYI--TTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
Score = 33.5 bits (73), Expect = 7.6
Identities = 27/134 (20%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 237 EILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIED 296
E +K +NE + E + Q T+ D K ++ Q+ + + V+K E EK++
Sbjct: 795 EKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKK 854
Query: 297 VALKPVRKDSLMDEKSSEISELQNER-----QITEKKESLQETQLQPTEKNKLLENIVSE 351
+ R ++DE +++ +L+N+ ++ +K ++E + + NK + ++ E
Sbjct: 855 ---EEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKE 911
Query: 352 ESKESTGKRRQREE 365
+ T ++R +
Sbjct: 912 VTAIETKLEQKRSD 925
>BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural
maintenance of chromosomes 1-like 1 protein.
Length = 1233
Score = 50.0 bits (114), Expect = 8e-05
Identities = 78/341 (22%), Positives = 138/341 (40%), Gaps = 44/341 (12%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
+E VK +E + RK +E+K+ Q D + + V KL
Sbjct: 173 KEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVK 263
+L + L E E R K + LK+K +E ++ ++Q K ++ K
Sbjct: 233 VEIEKLNKELASKN-----KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEK 287
Query: 264 D-ESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
D E QK P +A + K++K K+ +++ ++ MDE E+ ++ R
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKAR 347
Query: 323 QITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXX 382
Q E +E ++E L EN V + R +EE +++ L
Sbjct: 348 Q--EFEERMEEESQSQGRDLTLEENQVKK-------YHRLKEEASKRAATL--------- 389
Query: 383 XXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEK 442
+ + ++ K +DR++ ++ +K T+ IK + ++E+ EK
Sbjct: 390 ---------AQELEKFNRDQKADQDRLDLEERKKVE---TEAKIKQKLREIEENQKRIEK 437
Query: 443 FEDITLKPTRKQSLVD------EITEEVCALKSALDDIEKE 477
E+ T KQSL + E+TEEV K +D+I KE
Sbjct: 438 LEEYI--TTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
Score = 33.5 bits (73), Expect = 7.6
Identities = 27/134 (20%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 237 EILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIED 296
E +K +NE + E + Q T+ D K ++ Q+ + + V+K E EK++
Sbjct: 795 EKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKK 854
Query: 297 VALKPVRKDSLMDEKSSEISELQNER-----QITEKKESLQETQLQPTEKNKLLENIVSE 351
+ R ++DE +++ +L+N+ ++ +K ++E + + NK + ++ E
Sbjct: 855 ---EEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKE 911
Query: 352 ESKESTGKRRQREE 365
+ T ++R +
Sbjct: 912 VTAIETKLEQKRSD 925
>BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein.
Length = 847
Score = 50.0 bits (114), Expect = 8e-05
Identities = 78/341 (22%), Positives = 138/341 (40%), Gaps = 44/341 (12%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
+E VK +E + RK +E+K+ Q D + + V KL
Sbjct: 173 KEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVK 263
+L + L E E R K + LK+K +E ++ ++Q K ++ K
Sbjct: 233 VEIEKLNKELASKN-----KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEK 287
Query: 264 D-ESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
D E QK P +A + K++K K+ +++ ++ MDE E+ ++ R
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKAR 347
Query: 323 QITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXX 382
Q E +E ++E L EN V + R +EE +++ L
Sbjct: 348 Q--EFEERMEEESQSQGRDLTLEENQVKK-------YHRLKEEASKRAATL--------- 389
Query: 383 XXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEK 442
+ + ++ K +DR++ ++ +K T+ IK + ++E+ EK
Sbjct: 390 ---------AQELEKFNRDQKADQDRLDLEERKKVE---TEAKIKQKLREIEENQKRIEK 437
Query: 443 FEDITLKPTRKQSLVD------EITEEVCALKSALDDIEKE 477
E+ T KQSL + E+TEEV K +D+I KE
Sbjct: 438 LEEYI--TTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
>AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 50.0 bits (114), Expect = 8e-05
Identities = 78/341 (22%), Positives = 138/341 (40%), Gaps = 44/341 (12%)
Query: 144 EEHVKVQEVVETKLWRKPKTISEKKDLLQVSTHEDTNILKVENLESVNVDTTSSKLETKS 203
+E VK +E + RK +E+K+ Q D + + V KL
Sbjct: 173 KEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 204 WRKPRLEESLEEVGPTKGVNEPEVCHWRKPKTSEILKDKNEEEIRVQEMKKQSTKALEVK 263
+L + L E E R K + LK+K +E ++ ++Q K ++ K
Sbjct: 233 VEIEKLNKELASKN-----KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEK 287
Query: 264 D-ESKQKIPWTQEAIKLRPTKVEKSPIEKEKIEDVALKPVRKDSLMDEKSSEISELQNER 322
D E QK P +A + K++K K+ +++ ++ MDE E+ ++ R
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKAR 347
Query: 323 QITEKKESLQETQLQPTEKNKLLENIVSEESKESTGKRRQREEITQKEVALKTVRXXXXX 382
Q E +E ++E L EN V + R +EE +++ L
Sbjct: 348 Q--EFEERMEEESQSQGRDLTLEENQVKK-------YHRLKEEASKRAATL--------- 389
Query: 383 XXXXXXXXSLKPVLTTEKESKETEDRINTKDTRKPSIPWTQEAIKLRPTKMEKTPIEKEK 442
+ + ++ K +DR++ ++ +K T+ IK + ++E+ EK
Sbjct: 390 ---------AQELEKFNRDQKADQDRLDLEERKKVE---TEAKIKQKLREIEENQKRIEK 437
Query: 443 FEDITLKPTRKQSLVD------EITEEVCALKSALDDIEKE 477
E+ T KQSL + E+TEEV K +D+I KE
Sbjct: 438 LEEYI--TTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE 476
Score = 33.5 bits (73), Expect = 7.6
Identities = 27/134 (20%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 237 EILKDKNEEEIRVQEMKKQSTKALEVKDESKQKIPWTQEAIKLRPTKVEKSPIEKEKIED 296
E +K +NE + E + Q T+ D K ++ Q+ + + V+K E EK++
Sbjct: 795 EKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKK 854
Query: 297 VALKPVRKDSLMDEKSSEISELQNER-----QITEKKESLQETQLQPTEKNKLLENIVSE 351
+ R ++DE +++ +L+N+ ++ +K ++E + + NK + ++ E
Sbjct: 855 ---EEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKE 911
Query: 352 ESKESTGKRRQREE 365
+ T ++R +
Sbjct: 912 VTAIETKLEQKRSD 925
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 50.0 bits (114), Expect = 8e-05
Identities = 61/227 (26%), Positives = 95/227 (41%), Gaps = 34/227 (14%)
Query: 1392 TSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEE 1451
T V+E +VK VV G+ + + +A G P+P + W R+G++ L + YQ +
Sbjct: 344 TLTVQEPPHFVVKPRDQVVAL--GRTVTFQCEATGNPQPAIFWRREGSQNLLFS-YQPPQ 400
Query: 1452 LDDGTSI-----LTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWV 1506
S+ LT+ V + D G + + N G T A L V ++ R P +
Sbjct: 401 SSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD---RPPPVI 457
Query: 1507 THMEELQAALKATQSVP-TFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRT 1565
Q + T +V TFV + +G+P P ILW KD ++ T
Sbjct: 458 R-----QGPVNQTVAVDGTFV---------------LSCVATGSPVPTILWRKDGVLVST 497
Query: 1566 DERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ I+ EN I+ A G YTC A + G A A ++V
Sbjct: 498 QDS-RIKQLEN-GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEV 542
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 6/134 (4%)
Query: 1243 NISKDLIGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVL-APLENTTVMDGERISL 1301
N+ + +G C+ N AGS+ T V + D P++ P+ T +DG + L
Sbjct: 417 NVQRSDVGYYICQTLNVAGSIITKAYLEVTD-VIADRPPPVIRQGPVNQTVAVDGTFV-L 474
Query: 1302 NCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQF 1361
+C G P P I W + L+ T +D I + ++G+ + I+ A G Y C AS
Sbjct: 475 SCVATGSPVPTILWRKDGVLVST-QDSRIKQLENGV--LQIRYAKLGDTGRYTCIASTPS 531
Query: 1362 GKCSTECILNIEAY 1375
G+ + + ++ +
Sbjct: 532 GEATWSAYIEVQEF 545
Score = 47.2 bits (107), Expect = 6e-04
Identities = 34/115 (29%), Positives = 57/115 (49%), Gaps = 13/115 (11%)
Query: 1256 AENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRPWPKIDW 1315
++N S+ +GS + +E P ++ + V GE +LNCK GRP P I+W
Sbjct: 47 SDNDDNSLGYTGSRLRQEDF-----PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEW 101
Query: 1316 FHNEKLIETARDITISRQ---KSG----LCEIHIKEAFPEMAGIYKCTASNQFGK 1363
+ + +ET +D S + SG L +H +++ P+ G+Y C A N G+
Sbjct: 102 YKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD-EGVYVCVARNYLGE 155
Score = 40.7 bits (91), Expect = 0.050
Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 1523 PTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENRTTCTI 1582
P+FVK V ++ F+ G+P P + W KD+ + R+ I + T I
Sbjct: 262 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIRDDH---TLKI 317
Query: 1583 KKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+K T G+YTC A + +G A A L V
Sbjct: 318 RKVTAGDMGSYTCVAENMVGKAEASATLTV 347
Score = 38.3 bits (85), Expect = 0.27
Identities = 61/235 (25%), Positives = 96/235 (40%), Gaps = 49/235 (20%)
Query: 1390 EKTSDVEEFA----PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQST 1445
E+ S+V E P VK P+ + T + +A G P P VRW + EL +S
Sbjct: 248 ERESEVAELTVLERPSFVKR-PSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS- 305
Query: 1446 EYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEW 1505
Y+I DD T L + +V D G A E++VG E
Sbjct: 306 RYEIR--DDHT--LKIRKVTAGDMGSYTCVA---------------ENMVGKAE------ 340
Query: 1506 VTHMEELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDN----- 1560
+A Q P FV + + V VTF+ +GNP P I W ++
Sbjct: 341 -------ASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 393
Query: 1561 ---KVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTKAKLQV 1612
+ ++ RF + + T ++++ D+ G Y C+ ++ G +TKA L+V
Sbjct: 394 FSYQPPQSSSRFSVSQTGDLTITNVQRS--DV-GYYICQTLNVAGSIITKAYLEV 445
Score = 33.9 bits (74), Expect = 5.7
Identities = 59/228 (25%), Positives = 93/228 (40%), Gaps = 38/228 (16%)
Query: 1396 EEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQG--TELLQSTEYQIEELD 1453
E+F PRIV+ P+ + ++G+ L KA G P P + W + G E + L
Sbjct: 64 EDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLL 122
Query: 1454 DGTSILTMPEVY----QDDTGEIVFEAYNHLGVTATIAALSVESIVGTQEYRKPEWVTHM 1509
S+ + V+ + D G V A N+LG + A S+E + ++R+ +
Sbjct: 123 PSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNA-SLEVAILRDDFRQ-----NP 176
Query: 1510 EELQAALKATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVI-RTDER 1568
++ A+ P V E P R G+P P I W KD + DER
Sbjct: 177 SDVMVAV----GEPA-VMECQPPR--------------GHPEPTISWKKDGSPLDDKDER 217
Query: 1569 FIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK-AKLQVFQR 1615
I + T T K G Y C + +G ++ A+L V +R
Sbjct: 218 ITIRGGKLMITYTRKSDA----GKYVCVGTNMVGERESEVAELTVLER 261
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16 to
1881) protein.
Length = 1897
Score = 49.6 bits (113), Expect = 1e-04
Identities = 59/246 (23%), Positives = 101/246 (41%), Gaps = 33/246 (13%)
Query: 1251 VVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
+ C A N G ++TS S++EE+ G + + P + V ++ C G P
Sbjct: 94 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGP-QLKVVEKARTATMLCAAGGNP 152
Query: 1310 WPKIDWFHNEKLIETA-RDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+I WF + ++ A + I + +SG +I E + G Y+C A+N G
Sbjct: 153 DPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQ--GKYECVATNSAG-----T 205
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
+ A YV V APR P+ G + L A+G P
Sbjct: 206 RYSAPANLYV---------------RVRRVAPRF-SIPPSSQEVMPGGSVNLTCVAVGAP 249
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P V+W+ EL + +E+ G ++L + V + V A + LG+ A
Sbjct: 250 MPYVKWMMGAEELTKE-----DEMPVGRNVLELSNVVRSANYTCV--AISSLGMIEATAQ 302
Query: 1489 LSVESI 1494
++V+++
Sbjct: 303 VTVKAL 308
Score = 46.8 bits (106), Expect = 8e-04
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 25/205 (12%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +K +P T G + +A G PKP++ W+++G + + S +++ E DDG +
Sbjct: 23 PVFIK-VPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGAGSV 80
Query: 1460 TMPEVYQDDTGEIVFE--AYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
+ + E ++E A N LG T A LSV +E + P + ++ LK
Sbjct: 81 LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV-----LEEEQLPPGFPSI-DMGPQLK 134
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
+ T T GNP PEI W+KD + +
Sbjct: 135 VVEKART---------------ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 179
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIG 1602
I+ + + +G Y C A + G
Sbjct: 180 GALQIESSEESDQGKYECVATNSAG 204
Score = 44.4 bits (100), Expect = 0.004
Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 1279 GDA-PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
GD+ P+ + E+ T + G S C+ G P P+I W K + + R I
Sbjct: 19 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAG 78
Query: 1338 CEIHIKEAFPEM-AGIYKCTASNQFGKCSTECILNIEAYEYVP 1379
+ I+ + IY+CTA+N G+ +T L++ E +P
Sbjct: 79 SVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLP 121
Score = 36.3 bits (80), Expect = 1.1
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR-TT 1579
S P F+K + + +F +G P P I W K K + + +IE + +
Sbjct: 21 SKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV 80
Query: 1580 CTIK--KATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
I+ + +D E Y C A + +G T AKL V +
Sbjct: 81 LRIQPLRVQRD-EAIYECTATNSLGEINTSAKLSVLE 116
>X64698-1|CAA45939.1| 1100|Homo sapiens titin protein.
Length = 1100
Score = 49.6 bits (113), Expect = 1e-04
Identities = 43/113 (38%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 1255 RAENFAGSVSTSGSSIVEEQTCIDG-DAP-LVLAPL--ENTTVMDGERISLNC-KILGRP 1309
RA+N AG++S S E C D +AP +VL P + T+ G+ I LN ILG+P
Sbjct: 256 RAKNTAGAISAPSES-TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKP 314
Query: 1310 WPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFG 1362
PK W K I + DIT + IK A + AG Y TA+N FG
Sbjct: 315 LPKSSWSKAGKDIRPS-DITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 366
Score = 44.0 bits (99), Expect = 0.005
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 1409 VVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDD 1468
+V G I++E +G PKP V W ++G ++L+ T+ E ++IL + E + D
Sbjct: 981 LVIAKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSD 1039
Query: 1469 TGEIVFEAYNHLGVTATIAALSVESIVG 1496
+G A N +G + + V I G
Sbjct: 1040 SGPYPLTARNIVGEVGDVITIQVHDIPG 1067
Score = 41.1 bits (92), Expect = 0.038
Identities = 40/173 (23%), Positives = 75/173 (43%), Gaps = 11/173 (6%)
Query: 1231 IQPLKALNVLEENISKDLIGVVTCRAENFAGSVSTSGSS--IVEEQTCIDGDAPLVLAPL 1288
I +K L + N+++ A N AG + S IV+EQT + L L +
Sbjct: 921 ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP---ELDLRGI 977
Query: 1289 ENTTVMD--GERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGLCEIHIKEAF 1346
V+ G+ I + +LGRP P + W +++++ + + + ++I E
Sbjct: 978 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTI-LNINECV 1036
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFA 1399
+G Y TA N G+ ++ I+ ++ +P + DE +SD F+
Sbjct: 1037 RSDSGPYPLTARNIVGEVGD--VITIQVHD-IPGPPTGPIKFDEVSSDFVTFS 1086
Score = 37.5 bits (83), Expect = 0.47
Identities = 22/65 (33%), Positives = 29/65 (44%)
Query: 1548 GNPTPEILWYKDNKVIRTDERFIIENKENRTTCTIKKATKDLEGTYTCKAVSDIGLAVTK 1607
G P P+ W K K IR + I + + TIK AT+ G YT A + G V
Sbjct: 312 GKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 371
Query: 1608 AKLQV 1612
K+ V
Sbjct: 372 VKVTV 376
>M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor
protein.
Length = 943
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIK 1343
L P+ N T++ G+ L+CK+ G P P + W N+ +++ R I I + + G + I+
Sbjct: 65 LEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYG-SRLRIQ 123
Query: 1344 EAFPEMAGIYKCTASN 1359
+ G Y+C A+N
Sbjct: 124 DLDTTDTGYYQCVATN 139
Score = 35.1 bits (77), Expect = 2.5
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T +G+ L K G P P VRWL+ ++Q I + S L + ++ DT
Sbjct: 71 ITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDT 130
Query: 1470 GEIVFEAYNHL-GVTAT 1485
G A N + +TAT
Sbjct: 131 GYYQCVATNGMKTITAT 147
>BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIK 1343
L P+ N T++ G+ L+CK+ G P P + W N+ +++ R I I + + G + I+
Sbjct: 65 LEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYG-SRLRIQ 123
Query: 1344 EAFPEMAGIYKCTASN 1359
+ G Y+C A+N
Sbjct: 124 DLDTTDTGYYQCVATN 139
Score = 35.1 bits (77), Expect = 2.5
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T +G+ L K G P P VRWL+ ++Q I + S L + ++ DT
Sbjct: 71 ITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDT 130
Query: 1470 GEIVFEAYNHL-GVTAT 1485
G A N + +TAT
Sbjct: 131 GYYQCVATNGMKTITAT 147
>BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1264
Score = 49.6 bits (113), Expect = 1e-04
Identities = 42/168 (25%), Positives = 73/168 (43%), Gaps = 26/168 (15%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G+ C A+N G + ++G +E G P+++ + V DG+ ++L+C G
Sbjct: 375 VGMYQCVADNGIGFMHSTGRLEIEND---GGFKPVIITAPVSAKVADGDFVTLSCNASGL 431
Query: 1309 PWPKIDWFHNEKLIET---------ARDITISR-------------QKSGLCEIHIKEAF 1346
P P I W+ + LI + +R +SR ++G +HI+
Sbjct: 432 PVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVT 491
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
E AG Y C A+N+ G E L + +E + +E L D +D
Sbjct: 492 QEHAGKYICEAANEHGTTQAEASLMVVPFE-TNTKAETVTLPDAAQND 538
Score = 46.4 bits (105), Expect = 0.001
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 29/177 (16%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIE-TARDITISRQKSGLCEIHIKEAF 1346
L++ V G + C + G P P WFHN + I +AR +T +GL I
Sbjct: 318 LQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAG---NGL---KISGVT 371
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
E G+Y+C A N G ++ S ++ +D F P I+ A
Sbjct: 372 VEDVGMYQCVADNGIG--------------FMHSTGRLEIEND------GGFKPVIITA- 410
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
P +G + L A G+P P +RW L+ S Q+ S L+ PE
Sbjct: 411 PVSAKVADGDFVTLSCNASGLPVPVIRWY-DSHGLITSHPSQVLRSKSRKSQLSRPE 466
>BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1287
Score = 49.6 bits (113), Expect = 1e-04
Identities = 42/168 (25%), Positives = 73/168 (43%), Gaps = 26/168 (15%)
Query: 1249 IGVVTCRAENFAGSVSTSGSSIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGR 1308
+G+ C A+N G + ++G +E G P+++ + V DG+ ++L+C G
Sbjct: 375 VGMYQCVADNGIGFMHSTGRLEIEND---GGFKPVIITAPVSAKVADGDFVTLSCNASGL 431
Query: 1309 PWPKIDWFHNEKLIET---------ARDITISR-------------QKSGLCEIHIKEAF 1346
P P I W+ + LI + +R +SR ++G +HI+
Sbjct: 432 PVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVT 491
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSD 1394
E AG Y C A+N+ G E L + +E + +E L D +D
Sbjct: 492 QEHAGKYICEAANEHGTTQAEASLMVVPFE-TNTKAETVTLPDAAQND 538
Score = 46.4 bits (105), Expect = 0.001
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 29/177 (16%)
Query: 1288 LENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIE-TARDITISRQKSGLCEIHIKEAF 1346
L++ V G + C + G P P WFHN + I +AR +T +GL I
Sbjct: 318 LQDQIVSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAG---NGL---KISGVT 371
Query: 1347 PEMAGIYKCTASNQFGKCSTECILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKAL 1406
E G+Y+C A N G ++ S ++ +D F P I+ A
Sbjct: 372 VEDVGMYQCVADNGIG--------------FMHSTGRLEIEND------GGFKPVIITA- 410
Query: 1407 PTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPE 1463
P +G + L A G+P P +RW L+ S Q+ S L+ PE
Sbjct: 411 PVSAKVADGDFVTLSCNASGLPVPVIRWY-DSHGLITSHPSQVLRSKSRKSQLSRPE 466
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 49.6 bits (113), Expect = 1e-04
Identities = 59/246 (23%), Positives = 101/246 (41%), Gaps = 33/246 (13%)
Query: 1251 VVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
+ C A N G ++TS S++EE+ G + + P + V ++ C G P
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGP-QLKVVEKARTATMLCAAGGNP 162
Query: 1310 WPKIDWFHNEKLIETA-RDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+I WF + ++ A + I + +SG +I E + G Y+C A+N G
Sbjct: 163 DPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQ--GKYECVATNSAG-----T 215
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
+ A YV V APR P+ G + L A+G P
Sbjct: 216 RYSAPANLYV---------------RVRRVAPRF-SIPPSSQEVMPGGSVNLTCVAVGAP 259
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P V+W+ EL + +E+ G ++L + V + V A + LG+ A
Sbjct: 260 MPYVKWMMGAEELTKE-----DEMPVGRNVLELSNVVRSANYTCV--AISSLGMIEATAQ 312
Query: 1489 LSVESI 1494
++V+++
Sbjct: 313 VTVKAL 318
Score = 46.8 bits (106), Expect = 8e-04
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 25/205 (12%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +K +P T G + +A G PKP++ W+++G + + S +++ E DDG +
Sbjct: 33 PVFIK-VPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGAGSV 90
Query: 1460 TMPEVYQDDTGEIVFE--AYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
+ + E ++E A N LG T A LSV +E + P + ++ LK
Sbjct: 91 LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV-----LEEEQLPPGFPSI-DMGPQLK 144
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
+ T T GNP PEI W+KD + +
Sbjct: 145 VVEKART---------------ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 189
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIG 1602
I+ + + +G Y C A + G
Sbjct: 190 GALQIESSEESDQGKYECVATNSAG 214
Score = 44.4 bits (100), Expect = 0.004
Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 1279 GDA-PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
GD+ P+ + E+ T + G S C+ G P P+I W K + + R I
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAG 88
Query: 1338 CEIHIKEAFPEM-AGIYKCTASNQFGKCSTECILNIEAYEYVP 1379
+ I+ + IY+CTA+N G+ +T L++ E +P
Sbjct: 89 SVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLP 131
Score = 36.3 bits (80), Expect = 1.1
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR-TT 1579
S P F+K + + +F +G P P I W K K + + +IE + +
Sbjct: 31 SKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV 90
Query: 1580 CTIK--KATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
I+ + +D E Y C A + +G T AKL V +
Sbjct: 91 LRIQPLRVQRD-EAIYECTATNSLGEINTSAKLSVLE 126
>AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIK 1343
L P+ N T++ G+ L+CK+ G P P + W N+ +++ R I I + + G + I+
Sbjct: 65 LEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYG-SRLRIQ 123
Query: 1344 EAFPEMAGIYKCTASN 1359
+ G Y+C A+N
Sbjct: 124 DLDTTDTGYYQCVATN 139
Score = 35.1 bits (77), Expect = 2.5
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T +G+ L K G P P VRWL+ ++Q I + S L + ++ DT
Sbjct: 71 ITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDT 130
Query: 1470 GEIVFEAYNHL-GVTAT 1485
G A N + +TAT
Sbjct: 131 GYYQCVATNGMKTITAT 147
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 49.6 bits (113), Expect = 1e-04
Identities = 59/246 (23%), Positives = 101/246 (41%), Gaps = 33/246 (13%)
Query: 1251 VVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
+ C A N G ++TS S++EE+ G + + P + V ++ C G P
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGP-QLKVVEKARTATMLCAAGGNP 162
Query: 1310 WPKIDWFHNEKLIETA-RDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+I WF + ++ A + I + +SG +I E + G Y+C A+N G
Sbjct: 163 DPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQ--GKYECVATNSAG-----T 215
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
+ A YV V APR P+ G + L A+G P
Sbjct: 216 RYSAPANLYV---------------RVRRVAPRF-SIPPSSQEVMPGGSVNLTCVAVGAP 259
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P V+W+ EL + +E+ G ++L + V + V A + LG+ A
Sbjct: 260 MPYVKWMMGAEELTKE-----DEMPVGRNVLELSNVVRSANYTCV--AISSLGMIEATAQ 312
Query: 1489 LSVESI 1494
++V+++
Sbjct: 313 VTVKAL 318
Score = 46.8 bits (106), Expect = 8e-04
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 25/205 (12%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +K +P T G + +A G PKP++ W+++G + + S +++ E DDG +
Sbjct: 33 PVFIK-VPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGAGSV 90
Query: 1460 TMPEVYQDDTGEIVFE--AYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
+ + E ++E A N LG T A LSV +E + P + ++ LK
Sbjct: 91 LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV-----LEEEQLPPGFPSI-DMGPQLK 144
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
+ T T GNP PEI W+KD + +
Sbjct: 145 VVEKART---------------ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 189
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIG 1602
I+ + + +G Y C A + G
Sbjct: 190 GALQIESSEESDQGKYECVATNSAG 214
Score = 44.4 bits (100), Expect = 0.004
Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 1279 GDA-PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
GD+ P+ + E+ T + G S C+ G P P+I W K + + R I
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAG 88
Query: 1338 CEIHIKEAFPEM-AGIYKCTASNQFGKCSTECILNIEAYEYVP 1379
+ I+ + IY+CTA+N G+ +T L++ E +P
Sbjct: 89 SVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLP 131
Score = 36.3 bits (80), Expect = 1.1
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR-TT 1579
S P F+K + + +F +G P P I W K K + + +IE + +
Sbjct: 31 SKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV 90
Query: 1580 CTIK--KATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
I+ + +D E Y C A + +G T AKL V +
Sbjct: 91 LRIQPLRVQRD-EAIYECTATNSLGEINTSAKLSVLE 126
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 49.6 bits (113), Expect = 1e-04
Identities = 59/246 (23%), Positives = 101/246 (41%), Gaps = 33/246 (13%)
Query: 1251 VVTCRAENFAGSVSTSGS-SIVEEQTCIDGDAPLVLAPLENTTVMDGERISLNCKILGRP 1309
+ C A N G ++TS S++EE+ G + + P + V ++ C G P
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGP-QLKVVEKARTATMLCAAGGNP 162
Query: 1310 WPKIDWFHNEKLIETA-RDITISRQKSGLCEIHIKEAFPEMAGIYKCTASNQFGKCSTEC 1368
P+I WF + ++ A + I + +SG +I E + G Y+C A+N G
Sbjct: 163 DPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQ--GKYECVATNSAG-----T 215
Query: 1369 ILNIEAYEYVPSVSEEDVLSDEKTSDVEEFAPRIVKALPTVVTTTEGKLIRLEAKAIGIP 1428
+ A YV V APR P+ G + L A+G P
Sbjct: 216 RYSAPANLYV---------------RVRRVAPRF-SIPPSSQEVMPGGSVNLTCVAVGAP 259
Query: 1429 KPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDTGEIVFEAYNHLGVTATIAA 1488
P V+W+ EL + +E+ G ++L + V + V A + LG+ A
Sbjct: 260 MPYVKWMMGAEELTKE-----DEMPVGRNVLELSNVVRSANYTCV--AISSLGMIEATAQ 312
Query: 1489 LSVESI 1494
++V+++
Sbjct: 313 VTVKAL 318
Score = 46.8 bits (106), Expect = 8e-04
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 25/205 (12%)
Query: 1400 PRIVKALPTVVTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSIL 1459
P +K +P T G + +A G PKP++ W+++G + + S +++ E DDG +
Sbjct: 33 PVFIK-VPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKK-VSSQRFEVIEFDDGAGSV 90
Query: 1460 TMPEVYQDDTGEIVFE--AYNHLGVTATIAALSVESIVGTQEYRKPEWVTHMEELQAALK 1517
+ + E ++E A N LG T A LSV +E + P + ++ LK
Sbjct: 91 LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV-----LEEEQLPPGFPSI-DMGPQLK 144
Query: 1518 ATQSVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR 1577
+ T T GNP PEI W+KD + +
Sbjct: 145 VVEKART---------------ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRS 189
Query: 1578 TTCTIKKATKDLEGTYTCKAVSDIG 1602
I+ + + +G Y C A + G
Sbjct: 190 GALQIESSEESDQGKYECVATNSAG 214
Score = 44.4 bits (100), Expect = 0.004
Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 1279 GDA-PLVLAPLENTTVMDGERISLNCKILGRPWPKIDWFHNEKLIETARDITISRQKSGL 1337
GD+ P+ + E+ T + G S C+ G P P+I W K + + R I
Sbjct: 29 GDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAG 88
Query: 1338 CEIHIKEAFPEM-AGIYKCTASNQFGKCSTECILNIEAYEYVP 1379
+ I+ + IY+CTA+N G+ +T L++ E +P
Sbjct: 89 SVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLP 131
Score = 36.3 bits (80), Expect = 1.1
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 1521 SVPTFVKEIIPERVHEEEIVTFEAIYSGNPTPEILWYKDNKVIRTDERFIIENKENR-TT 1579
S P F+K + + +F +G P P I W K K + + +IE + +
Sbjct: 31 SKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV 90
Query: 1580 CTIK--KATKDLEGTYTCKAVSDIGLAVTKAKLQVFQ 1614
I+ + +D E Y C A + +G T AKL V +
Sbjct: 91 LRIQPLRVQRD-EAIYECTATNSLGEINTSAKLSVLE 126
>AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 1285 LAPLENTTVMDGERISLNCKILGRPWPKIDWFHNE-KLIETARDITISRQKSGLCEIHIK 1343
L P+ N T++ G+ L+CK+ G P P + W N+ +++ R I I + + G + I+
Sbjct: 65 LEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYG-SRLRIQ 123
Query: 1344 EAFPEMAGIYKCTASN 1359
+ G Y+C A+N
Sbjct: 124 DLDTTDTGYYQCVATN 139
Score = 35.1 bits (77), Expect = 2.5
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 1410 VTTTEGKLIRLEAKAIGIPKPQVRWLRQGTELLQSTEYQIEELDDGTSILTMPEVYQDDT 1469
+T +G+ L K G P P VRWL+ ++Q I + S L + ++ DT
Sbjct: 71 ITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDT 130
Query: 1470 GEIVFEAYNHL-GVTAT 1485
G A N + +TAT
Sbjct: 131 GYYQCVATNGMKTITAT 147
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.308 0.126 0.352
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 227,010,030
Number of Sequences: 224733
Number of extensions: 8648061
Number of successful extensions: 46532
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 350
Number of HSP's successfully gapped in prelim test: 1483
Number of HSP's that attempted gapping in prelim test: 32634
Number of HSP's gapped (non-prelim): 13294
length of query: 1910
length of database: 73,234,838
effective HSP length: 101
effective length of query: 1809
effective length of database: 50,536,805
effective search space: 91421080245
effective search space used: 91421080245
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.6 bits)
S2: 73 (33.5 bits)
- SilkBase 1999-2023 -